40,383 results match your criteria Refractive Eyecare [Journal]


Effects of posterior scleral reinforcement in pathological myopia: a 3-year follow-up study.

Graefes Arch Clin Exp Ophthalmol 2018 Dec 15. Epub 2018 Dec 15.

Department of Ophthalmology, the Fourth Affiliated Hospital of China Medical University, Eye Hospital of China Medical University, Key Laboratory of Lens Research of Liaoning Province, Shenyang, China.

Purpose: To assess the effects of posterior sclera reinforcement (PSR) in refractive outcomes, choroidal thickness (CT), and retinal thickness (RT) during a 3-year follow-up in eyes with pathological myopia.

Methods: Thirty-eight eyes of 26 adults with pathological myopia who underwent PSR (the PSR group) and 30 eyes of 18 adults with matched age and myopia who did not receive PSR treatment (the control group) were followed up with measurements of axial length (AL), spherical equivalent (SE), best corrected visual acuity (BCVA), CT, and RT at baseline, 1 and 3 months, and 1, 2, and 3 years postoperatively. Data were analyzed by repeated measures analysis of variance and independent-samples t test. Read More

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December 2018

Color-sensitive and spectrometer-free plasmonic sensor for biosensing applications.

Biosens Bioelectron 2018 Dec 7;126:743-750. Epub 2018 Dec 7.

Department of Information and Communication Engineering, Daegu Gyeongbuk Institute of Science & Technology (DGIST), Daegu 42988, Republic of Korea. Electronic address:

A color-sensitive and spectrometer-free sensing method using plasmonic nanohole arrays and the color components, L* , a* , and b* , of the CIELAB defined by the international commission on illumination (CIE) is introduced for the analysis of optically transparent materials in the visible range. Spectral analysis based on plasmonic nanoparticles or nanostructures can be applied to real-time bio-detection, but complex optical instrumentations and low spatial resolution have limited the sensing ability. Therefore, we take an advantage of color image processing instead of spectral analysis which induces the distinctive color information of plasmonic nanohole arrays with different transparent materials. Read More

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December 2018
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Predictive factors for efficacy and safety in refractive surgery for myopia.

PLoS One 2018 14;13(12):e0208608. Epub 2018 Dec 14.

Department of Ophthalmology, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.

Purpose: To evaluate the predictive factors for safety and efficacy in laser refractive surgery for myopia.

Setting: A singular refractive surgery center, at a University-affiliated tertiary medical center.

Design: Retrospective cohort study. Read More

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December 2018
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Fourier Analysis of Corneal Irregular Astigmatism Due to the Anterior Corneal Surface in Dry Eye.

Eye Contact Lens 2018 Dec 11. Epub 2018 Dec 11.

Departments of Innovative Visual Science (S.K., K.M.), and Ophthalmology (S.K., N.M., M.O., S.A., Y.T., K.M., K.N.), Osaka University Graduate School of Medicine, Osaka, Japan; Research and Development Division (Y.T.), Rohto, Kyoto, Japan; and Department of Ophthalmology, Icahn School of Medicine at Mount Sinai (S.D.K.), New York, NY.

Objectives: To evaluate corneal irregular astigmatism due to the anterior corneal surface using Fourier harmonic analysis with a Placido ring-based corneal topographer (Placido-based topographer) and three-dimensional anterior segment optical coherence tomography (OCT) in dry eyes.

Methods: Forty-four eyes of 44 subjects with dry eye and 20 eyes of 20 normal control subjects were enrolled. Corneal topographic data were obtained using a Placido-based topographer and OCT. Read More

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December 2018

Comparison of Intraocular Lens Power Calculation Methods Following Myopic Laser Refractive Surgery: New Options Using a Rotating Scheimpflug Camera.

Korean J Ophthalmol 2018 Dec;32(6):497-505

Department of Ophthalmology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

Purpose: To evaluate and compare published methods of calculating intraocular lens (IOL) power following myopic laser refractive surgery.

Methods: We performed a retrospective review of the medical records of 69 patients (69 eyes) who had undergone myopic laser refractive surgery previously and subsequently underwent cataract surgery at Samsung Medical Center in Seoul, South Korea from January 2010 to June 2016. None of the patients had pre-refractive surgery biometric data available. Read More

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December 2018
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Anti-vascular Endothelial Growth Factor Treatment of Retinopathy of Prematurity: Efficacy, Safety, and Anatomical Outcomes.

Korean J Ophthalmol 2018 Dec;32(6):451-458

Department of Ophthalmology, Institute of Vision Research, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.

Purpose: To investigate the efficacy, safety, and anatomical outcomes associated with intravitreal anti-vascular endothelial growth factor (VEGF) treatment of retinopathy of prematurity (ROP).

Methods: We performed a retrospective review of intravitreal anti-VEGF (bevacizumab or ranibizumab) treatment of 153 eyes (83 infants) diagnosed with ROP at two tertiary hospitals from June 2011 to January 2017. The primary outcome was the rate of recurrence requiring additional treatment; secondary outcomes included incidence of major complications and final refractive error. Read More

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December 2018

Inscribing diffraction gratings in bulk silicon with nanosecond laser pulses.

Opt Lett 2018 Dec;43(24):6069-6072

Diffraction gratings are transversally inscribed in the bulk of monolithic crystalline silicon with infrared nanosecond laser pulses. Nanoscale material analyses of the modifications composing the gratings show that they rely on laser-induced stress associated with a positive refractive index change as confirmed with phase-shift interferometry. Characterizations of the optical properties of the gratings, including the diffraction angles and the efficiency of the different orders, are carried out. Read More

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December 2018

Fiber optic refractive index sensors through spectral detection of Rayleigh backscattering in a chemically etched MgO-based nanoparticle-doped fiber.

Opt Lett 2018 Dec;43(24):5945-5948

We demonstrate and experimentally validate a fiber optic refractive index (RI) sensor obtained by simply etching a high-scattering MgO-based nanoparticle-doped single-mode fiber in hydrofluoric acid (HF). The fiber has 32.3 dB stronger Rayleigh scattering than a standard fiber, allowing a detection of scattering spectral signatures with an optical backscatter reflectometer, even when the core is exposed to the outer RI. Read More

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December 2018

70  μm diameter optical probe for common-path optical coherence tomography in air and liquids.

Opt Lett 2018 Dec;43(24):5929-5932

We investigate and validate a novel method to fabricate ultrathin optical probes for common-path optical coherence tomography (CP-OCT). The probes are obtained using a 65 μm barium titanate microsphere inserted into an inward concave cone chemically etched at the end of a single-mode fiber. We demonstrate that the high refractive index (n=1. Read More

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December 2018

Punctate Inner Choroidopathy and Choroidal Neovascularization in Korean Patients.

Ocul Immunol Inflamm 2018 Dec 14:1-6. Epub 2018 Dec 14.

a Department of Ophthalmology, The Institute of Vision Research , Yonsei University College of Medicine , Seoul , South Korea.

Purpose: To describe the clinical features and outcomes of punctate inner choroidopathy (PIC) in Korean patients Methods: We retrospectively reviewed the medical records of patients with PIC between 2004 and 2015. The main outcome measures included best-corrected visual acuity (BCVA), presence of choroidal neovascularization (CNV), and optical coherence tomography findings. Patients with and without CNV were compared. Read More

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December 2018

Inverse Doppler Effects in Pipe Instruments.

Sci Rep 2018 Dec 13;8(1):17833. Epub 2018 Dec 13.

Smart Materials Laboratory, Department of Applied Physics, Northwestern Polytechnical University, Xi'an, 710129, P. R. China.

Music is older than language, and for most of human history music holds our culture together. The pipe instrument is one of the most popular musical instruments of all time. Built on the foundation of previous flute and flute-like acoustic metamaterial models, we herein report the experimental results of the inverse Doppler effects discovered in two common pipe instruments - recorder and clarinet. Read More

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December 2018

Facile Fabrication of Amorphous Photonic Structures with Non-Iridescent and Highly-Stable Structural Color on Textile Substrates.

Materials (Basel) 2018 Dec 8;11(12). Epub 2018 Dec 8.

Engineering Research Center for Eco-Dyeing and Finishing of Textiles, Ministry of Education, Zhejiang Sci-Tech University, Hangzhou 310018, China.

Amorphous photonic structures with non-iridescent and highly-stable structural color were fabricated via a simple one-step spray-coating technique. With this strategy, the obtained films on textile substrates presented short-ordered and amorphous photonic structures (APSs) similar to the amorphous nanostructures of avian feathers. The structural color presented the same hue when viewed at different angles and could be well controlled by varying the diameters of the SiO₂ nanospheres. Read More

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December 2018

Modulation of the Antibiotic Activity by the (Buriti) Fixed Oil against Methicillin-Resistant Staphylococcus Aureus (MRSA) and Other Multidrug-Resistant (MDR) Bacterial Strains.

Pathogens 2018 Dec 10;7(4). Epub 2018 Dec 10.

Technology Center, Laboratory Analysis Physical Chemistry of Food, Faculty of Technology Cariri, Juazeiro do Norte 63041-190, Brazil.

(buriti) is a typical Brazilian palm tree found in swampy regions with many plant forms. The fruit has various purposes with the pulps to the seeds being used for ice creams, sweets, creams, jellies, liqueurs, and vitamin production. A physicochemical characterization of the fixed pulp oil and its antibacterial and aminoglycoside antibiotic modifying activity against Gram-positive and Gram-negative multiresistant bacterial strains were performed using broth microdilution assays. Read More

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December 2018

Optical Fiber Magnetic Field Sensors Based on Magnetic Fluid: A Review.

Sensors (Basel) 2018 Dec 7;18(12). Epub 2018 Dec 7.

Instituto de Telecomunicações, Campus Universitário de Santiago, 3810-193 Aveiro, Portugal.

Magnetic field sensing is an important issue for many application areas, such as in the military, industry and navigation. The current sensors used to monitor this parameter can be susceptible to electromagnetic interferences, however due to their advantages over the traditional sensors, the optical fiber devices could be an excellent alternative. Furthermore, magnetic fluid (MF) is a new type of functional material which possesses outstanding properties, including Faraday effect, birefringence, tunable refractive index and field dependent transmission. Read More

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December 2018

Retrospective observational study of micro-monovision small incision lenticule extraction (SMILE) for the correction of presbyopia and myopia.

Medicine (Baltimore) 2018 Dec;97(49):e13586

Department of Ophthalmology and Visual Science, Daejeon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.

This study was aimed to evaluate refractive and visual outcomes after micro-monovision small incision lenticule extraction (SMILE) in patients with presbyopia and myopia. In total, 72 patients (144 eyes) with a mean age of 46.0 ± 4. Read More

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December 2018

Outcomes of a 320-degree intrastromal corneal ring segment implantation for keratoconus: Results of a 6-month follow-up.

Eur J Ophthalmol 2018 Dec 12:1120672118818018. Epub 2018 Dec 12.

4 Escola Paulista de Medicina (EPM), Federal University of São Paulo (UNIFESP), São Paulo, Brazil.

Importance:: This study shows that a newer long-arc length intrastromal corneal ring segment is efficient and safe for keratoconus treatment.

Background:: To evaluate visual, tomographic results and complications of a 320-degree intrastromal corneal ring segment implantation with the femtosecond laser for keratoconus treatment.

Design:: A prospective, nonrandomized, and interventional study. Read More

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December 2018

Change of tear osmolarity after refractive surgery.

Cesk Slov Oftalmol 2018 ;74(1):18-22

  Purpose: To compare the influence of the LASIK and ReLEx SMILE refractive method on tear osmolarity Methods: Prospective non-randomized comparative study. We evaluated the results in two groups of patients who underwent binocular refractive surgery to remove myopia and possibly astigmatism in the eye clinic of Horní Počernice. In each group were 15 patients (30 eyes), patients of one group undergoing FS-LASIK refractive surgery, in the second group a ReLEx SMILE procedure. Read More

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January 2018

Comparative Analysis of the Safety and Functional Outcomes of Anterior versus Retropupillary Iris-Claw IOL Fixation.

J Ophthalmol 2018 4;2018:8463569. Epub 2018 Nov 4.

Ophthalmology Unit, University Hospital of Parma, Parma, Italy.

Purpose: To compare the functional and clinical outcomes of the iris-claw intraocular lens (IOL) placed on the anterior versus posterior surface of the iris.

Patients And Methods: A multicenter, retrospective study. Data on eyes that underwent anterior or retropupillary iris-claw IOL implantation because of inadequate capsular support secondary to complicated cataract surgery, trauma, and dislocated/opacified IOLs since January 2015 were analyzed. Read More

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November 2018

Prevalence of Myopia among Children Attending Pediatrics Ophthalmology Clinic at Ohud Hospital, Medina, Saudi Arabia.

J Ophthalmol 2018 7;2018:3708409. Epub 2018 Nov 7.

MD, FRCSEdn, Consultant Pediatric Ophthalmologist, RTPD Ophthalmology Program, Ohud Hospital, Madina, Saudi Arabia.

Introduction: Around half of the visually impaired population has uncorrected refractive errors (URE), and myopia constitutes a high proportion of them. URE should be screened and treated early to prevent long-term complications. The aim of this study was to determine the prevalence of myopia among all patients attending a pediatric outpatient clinic at Ohud Hospital in Medina, Saudi Arabia (KSA). Read More

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November 2018

Intraocular Pressure After Corneal Refractive Surgery.

Med Arch 2018 Nov;72(5):341-343

Clinic Gjermane e Syrit, Prishtina, Republic of Kosovo.

Introduction: Laser in situ keratomileusis (LASIK), a refractive surgery procedure is being performed in a large number among people with refractive errors. In all the people undergoing the procedure, there is a potential risk to misdiagnose the glaucoma disease due to changes in central corneal thickness (CCT). In subjects who have undergone laser refractive interventions, intraocular tension may be lower and underestimated, and this can lead to later detection of glaucoma. Read More

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November 2018

Enhanced light extraction from organic light-emitting diodes using a quasi-periodic nano-structure.

Nanotechnology 2018 Nov 30. Epub 2018 Nov 30.

Department of Electrical Engineering, Korea University, #204, 5-1 Anam-Dong, Seongbuk-Gu, Seoul 136-713, KOREA, Seoul, KOREA, REPUBLIC OF.

Organic light-emitting diodes (OLEDs) with a quasi-periodic nano-structure (QPS) were fabricated via a combination of laser interference lithography (LIL) and reactive ion etching (RIE). The LIL process was used to generate a periodic pattern, whereas the RIE process was used as a supplement to add randomness to the periodic pattern. The period of the fabricated periodic pattern was determined by finite difference time domain (FDTD) solutions. Read More

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November 2018

Approximate and explicit expression of optical forces and pull-in instability of a silicon nano-optomechanical device.

Nanotechnology 2018 Dec 3. Epub 2018 Dec 3.

Harbin Institute of Technology, Harbin, 150001, CHINA.

Nano-optomechanical systems actuated by optical forces enable many interesting scientific and technological applications. They are vulnerable to the effects of surface stress and Casimir forces. Therefore, calculation of optical forces is essential for the reliability applications of these advanced devices. Read More

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December 2018

Longitudinal Chromatic Aberration and Polychromatic Image Quality Metrics of Intraocular Lenses.

J Refract Surg 2018 Dec;34(12):832-838

Purpose: To measure longitudinal chromatic aberration (LCA) of various intraocular lenses (IOLs) and to assess LCA effects on polychromatic image quality with a focus on multifocal IOL designs.

Methods: The LCA values of four multifocal IOL models (three diffractive models: AT LARA 829MP and AT LISA 809M [both from Carl Zeiss Meditec AG, Jena, Germany] and Restor SN6AD1 [Alcon Laboratories, Inc., Fort Worth, TX] and one refractive model [Mini Well Ready; SIFI Medtech, Sant'Antonio, Italy]) were compared with that of their monofocal counterparts. Read More

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December 2018

Clinical Outcomes Using a Novel Image-Guided Planning System in Patients With Cataract and IOL Implantation.

J Refract Surg 2018 Dec;34(12):824-831

Purpose: To determine the proportion of eyes with preexisting astigmatism achieving 0.50 diopters (D) or less of residual refractive cylinder 3 months after either implantation of toric intraocular lenses (IOLs) or corneal incisions using the VERION system (Alcon Laboratories, Inc., Fort Worth, TX) measurement module and digital markers for microscope (M) and laser (L). Read More

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December 2018
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A Novel Near-infrared Hyperspectral Absorption/Scattering Imaging Method using Multiple Ground Plates for Evaluating Polymer Composites.

Anal Chem 2018 Dec 12. Epub 2018 Dec 12.

This paper proposes a nondestructive method of evaluating polymer composites using near-infrared (NIR) diffuse reflection spectroscopy with multiple ground plates. Wavelength-dependent absorption and reduced scattering coefficients were acquired to evaluate the chemical structure and the concentration of the substances from absorption and to determine the size and the dispersity of filler in the polymer domain from scattering. NIR spectra of the sample were measured on multiple ground plates, namely, "ground-plate-dependent" diffuse reflection spectra. Read More

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December 2018

Comparison between Transepithelial Photorefractive Keratectomy versus Alcohol-Assisted Photorefractive Keratectomy in Correction of Myopia and Myopic Astigmatism.

J Ophthalmol 2018 12;2018:5376235. Epub 2018 Nov 12.

Ophthalmology Department, Security Forces Hospital, Riyadh, Saudi Arabia.

Purpose: The aim of the study was to compare visual acuity, refractive results, safety, and efficacy of TPRK with AAPRK as primary outcomes and surgical time, pain scores, haze levels, and healing time as secondary outcomes in TPRK and AAPRK groups.

Setting: Security Forces Hospital, Ophthalmology Department, Riyadh, Kingdom of Saudi Arabia.

Design: Prospective, nonrandomized case-control comparative study. Read More

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November 2018

Evaluation estrogen, progesteron and androgen receptor expressions in corneal epithelium in keratoconus.

Cont Lens Anterior Eye 2018 Dec 8. Epub 2018 Dec 8.

Hacettepe University, Bioengineering, Ankara, Turkey.

Purpose: To evaluate the role of sex steroid hormone receptors in corneal epithelium in etiopathogenesis of keratoconus (KC).

Methods: Thirty patients with KC who were planned for corneal collagen-crosslinking and 20 patients who were planned for excimer laser for refractive errors included in this study. Corneal epitheliums were curated mechanically during surgeries. Read More

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December 2018
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A New Method to Analyze the Relative Corneal Refractive Power and Its Association to Myopic Progression Control With Orthokeratology.

Transl Vis Sci Technol 2018 Nov 30;7(6):17. Epub 2018 Nov 30.

School of Optometry and Ophthalmology, Tianjin Medical University Eye Hospital, Tianjin, China.

Purpose: We present a new method for analyzing relative corneal refractive power (RCRP) in children undergoing orthokeratology and explore its potential association to effective myopic control.

Methods: A total of 55 children aged 8 to 12 years participated in the study. Axial growth was calculated as the difference in axial length before and 1 year after orthokeratology. Read More

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November 2018

Pentacam HR Indices Variation in Normal Corneas with Different Corneal Thickness.

J Ophthalmol 2018 8;2018:9328120. Epub 2018 Nov 8.

Ophthalmology Department, Cairo University, Al Watany Eye Hospital and Watany Research and Development Center (WRDC), Cairo, Egypt.

Purpose: To evaluate the effect of variable corneal thickness on Pentacam HR diagnostic indices in normal corneas.

Methods: Retrospective study was conducted at Al Watany Eye Hospital, Cairo, Egypt. Consecutive 160 eyes of young myopic subjects without KC were evaluated using Pentacam HR (WaveLight Allegro Oculyzer II, Erlangen, Germany). Read More

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November 2018
2 Reads

Femtosecond Laser-Assisted Deep Lamellar Descemet Membrane Endothelial Keratoplasty for the Treatment of Endothelial Dysfunction Associated With Posterior Stromal Scarring.

Cornea 2018 Dec 7. Epub 2018 Dec 7.

Cornea, Cataract and Refractive Surgery Unit, Vissum Corporación, Alicante, Spain.

Purpose: To describe an alternative surgical approach, femtosecond laser-assisted deep lamellar Descemet membrane endothelial keratoplasty (Femto-DL-DMEK), for the treatment of corneal endothelial diseases associated with posterior stromal scarring.

Methods: Case report of a 52-year-old man with pseudophakic bullous keratopathy and posterior corneal scarring secondary to viral endotheliitis who underwent Femto-DL-DMEK. The surgical technique was as follows: First, a manual lamellar dissection plane was created at approximately 75% to 85% depth through a 5. Read More

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December 2018

Estimation of refractive index for biological tissue using micro-optical coherence tomography.

IEEE Trans Biomed Eng 2018 Dec 10. Epub 2018 Dec 10.

The refractive index of biological tissue is required for investigating the tissue's optical properties. Efforts have been made to characterize refractive indices of biological tissues at a single wavelength, but it is more convenient to know the Cauchy's coefficients, which provide refractive index over a wide range of wavelengths. We demonstrate a method to noninvasively provide the Cauchy's dispersion coefficients of biological tissues using micro-optical coherence tomography. Read More

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December 2018

Changes in aqueous oxidative stress, prostaglandins, and cytokines: Comparisons of low-energy femtosecond laser-assisted cataract surgery versus conventional phacoemulsification.

J Cataract Refract Surg 2018 Dec 5. Epub 2018 Dec 5.

From the Cornea and Refractive Surgery Group (Liu, Setiawan, Ang, Yam, Mehta), Eye Research Institute, the Singapore National Eye Centre (Liu, Ang, Mehta), and the Duke-NUS Medical School (Liu, Yam, Mehta), Singapore. Electronic address:

Purpose: To compare the aqueous oxidative stress, prostaglandin E (PGE), and cytokine levels after low-energy femtosecond laser-assisted cataract surgery versus conventional phacoemulsification, and to evaluate the effect of a nonsteroidal antiinflammatory drug (NSAID) on the aqueous profiles.

Setting: Singapore National Eye Center, Singapore.

Design: Randomized controlled trial. Read More

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December 2018

Development and application of the multi-wavelength cavity ring-down aerosol extinction spectrometer.

J Environ Sci (China) 2019 Feb 7;76:227-237. Epub 2018 May 7.

State Key Laboratory for Structural Chemistry of Unstable and Stable Species, CAS Research/Education Center for Excellence in Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China; University of Chinese Academy of Sciences, Beijing 100049, China.

To better characterize the optical properties of atmospheric aerosols, the multi-wavelength cavity ring-down aerosol extinction spectrometer (MCRD-AES) is developed and applied in this study. By using tunable light source and four parallel cavities, the MCRD-AES covers a wide and atmospherically relevant wavelength range from 360 to 663 nm. Four wavelengths (375 nm, 440 nm, 532 nm, and 620 nm) are particularly tested with ammonium sulfate and nigrosine. Read More

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February 2019
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Improving toric intraocular lens calculations using total surgically induced astigmatism for a 2.5 mm temporal incision.

J Cataract Refract Surg 2018 Dec 6. Epub 2018 Dec 6.

From the Department of Ophthalmology (Holladay), Baylor College of Medicine, Houston, and Alcon Research Laboratories (Pettit), Dallas, Texas, USA.

Purpose: To determine in cataract surgery the total surgically induced astigmatism (SIA) that accounts for all factors that contribute to the difference between preoperative keratometric and postoperative refractive astigmatism other than any toricity of an intraocular lens (IOL).

Setting: Twenty surgical sites in the United States.

Design: Retrospective case series. Read More

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December 2018

Process evaluation of a National Primary Eye Care Programme in Rwanda.

BMC Health Serv Res 2018 Dec 7;18(1):950. Epub 2018 Dec 7.

Africa Vision Research Institute, Durban, South Africa, University of Calabar, Calabar, Nigeria.

Background: Visual impairment is a global public health problem, with an estimated 285 million affected globally, of which 43% are due to refractive error. A lack of specialist eye care in low and middle-income countries indicates a new model of care would support a task-shifting model and address this urgent need. We describe the features and results of the process evaluation of a national primary eye care (PEC) programme in Rwanda. Read More

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December 2018
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Anisotropic Quantum Well Electro-Optics in Few-Layer Black Phosphorus.

Nano Lett 2018 Dec 7. Epub 2018 Dec 7.

The incorporation of electrically tunable materials into photonic structures such as waveguides and metasurfaces enables dynamic, electrical control of light propagation at the nanoscale. Few-layer black phosphorus is a promising material for these applications due to its in-plane anisotropic, quantum well band structure, with a direct band gap that can be tuned from 0.3 eV to 2 eV with number of layers and subbands that manifest as additional optical transitions across a wide range of energies. Read More

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December 2018
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Second harmonic spectroscopy of surface lattice resonances.

Nano Lett 2018 Dec 7. Epub 2018 Dec 7.

Because of their large figures of merit, surface lattice resonances (SLRs) in metal nanoparticle arrays are very promising for chemical and biomolecular sensing, in both liquid and gas media. SLRs are sensitive to refractive index changes both near the surface of the nanoparticles (surface sensitivity) and in the volume between them (bulk sensitivity). Due to its intrinsic surface-sensitivity and a power-law dependence on electric fields, second harmonic generation (SHG) spectroscopy can improve upon both the surface and volume sensitivities of SLRs. Read More

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December 2018

Opposing Effects of PPARα Agonism and Antagonism on Refractive Development and Form Deprivation Myopia in Guinea Pigs.

Invest Ophthalmol Vis Sci 2018 Dec;59(15):5803-5815

School of Ophthalmology and Optometry and Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China.

Purpose: To determine if drug-induced peroxisome proliferator-activated receptor α (PPARα) signal pathway modulation affects refractive development and myopia in guinea pigs.

Methods: Pigmented guinea pigs were randomly divided into normal vision (unoccluded) and form deprivation myopia (FDM) groups. Each group received daily peribulbar injections of either a vehicle or (1) PPARα agonist, GW7647, clofibrate, or bezafibrate or (2) PPARα antagonist, GW6471, for 4 weeks. Read More

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December 2018
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Tailoring Fano lineshapes using plasmonic nanobars for highly sensitive sensing and directional emission.

Phys Chem Chem Phys 2018 Dec 6. Epub 2018 Dec 6.

Guangdong Provincial Key Laboratory of Nanophotonic Functional Materials and Devices, School of Information and Optoelectronic Science and Engineering, South China Normal University, Guangzhou 510006, China.

Plasmonic oligomers are one class of the most promising nanoclusters for generating Fano resonances. This study reveals that a nanobar-based heptamer concurrently sustains triple polarization-dependent Fano resonances, in sharp contrast to traditional nanodisk or nanosphere-based counterparts. Benefiting from the enhanced near field and reduced spectral linewidth, the gold heptamer exhibits a high refractive index sensitivity (940 nm per RIU) together with a figure of merit (FoM) value as large as 20. Read More

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December 2018
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Chloroquine Protects Human Corneal Epithelial Cells from Desiccation Stress Induced Inflammation without Altering the Autophagy Flux.

Biomed Res Int 2018 1;2018:7627329. Epub 2018 Nov 1.

GROW Research Laboratory, Narayana Nethralaya Foundation, Bangalore, Karnataka, India.

Dry eye disease (DED) is a multifactorial ocular surface disorder affecting millions of individuals worldwide. Inflammation has been associated with dry eye and anti-inflammatory drugs are now being targeted as the alternate therapeutic approach for dry eye condition. In this study, we have explored the anti-inflammatory and autophagy modulating effect of chloroquine (CQ) in human corneal epithelial and human corneal fibroblasts cells exposed to desiccation stress, (an model for DED). Read More

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November 2018
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Off-Label Use of Phakic Intraocular Lens with a "Piggyback" Technique.

Case Rep Ophthalmol 2018 Sep-Dec;9(3):465-472. Epub 2018 Nov 21.

University of Washington Department of Ophthalmology, Seattle, Washington, USA.

Purpose: We report a case of a highly myopic pseudophakic patient who received off-label placement of a phakic intraocular lens (pIOL) via a "piggyback" technique, allowing the placement of an intraocular lens (IOL) in his fellow eye, resulting in improved visual acuity and emmetropia.

Case Report: A 66-year-old, highly myopic, pseudophakic male with an IOL implant in his left eye was referred for second opinion for surgical options for his phakic right eye. Given the severe myopic status of both eyes, he received off-label placement of a posterior chamber pIOL with a piggyback technique for the pseudophakic left eye followed by standard cataract surgery and intraocular lens implantation in the right eye. Read More

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November 2018
9 Reads

Comparing spectacle and toric contact lens prescribing trends for astigmatism.

Clin Optom (Auckl) 2018 8;10:119-127. Epub 2018 Nov 8.

DAVICH Optical Chain, Daechi-dong, Gangnam-gu, Seoul, South Korea.

Background: The purpose of this study is to investigate and compare spectacle and contact lens (CL) prescription trends, with an emphasis on astigmatic refractive error prescribing differences for patients who purchase spectacles or CLs in South Korea.

Methods: A retrospective study of patient records of a major optical chain in South Korea was conducted. De-identified data of age, gender, power of prescribed spectacles and/or CLs were extracted from the practice database. Read More

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November 2018
1 Read

Patient-reported outcomes of multifocal and accommodating intraocular lenses: analysis of 117 patients 2-10 years after surgery.

Clin Ophthalmol 2018 12;12:2297-2304. Epub 2018 Nov 12.

Harvard Eye Associates, Laguna Hills, CA, USA,

Purpose: The purpose of this study was to determine the satisfaction levels of patients at least 2 years after cataract surgery implantation with bilateral accommodating or bilateral multifocal intraocular lenses (IOLs) and to determine the relative rate of spectacle independence and adverse symptoms in that same time frame.

Design: Patient questionnaire administered in a single-center private practice at least 2 years after cataract surgery with presbyopia-correcting IOL implantation.

Methods: Patients who had undergone uncomplicated cataract surgery with an accommodating or multifocal IOL implant were eligible for inclusion. Read More

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November 2018

Association of Pallidal Neurostimulation and Outcome Predictors With X-linked Dystonia Parkinsonism.

JAMA Neurol 2018 Dec 3. Epub 2018 Dec 3.

Institute of Neurogenetics, University of Lübeck, Lübeck, Germany.

Importance: Anecdotal evidence suggests that deep brain stimulation (DBS) of the internal globus pallidus (GPi) is effective in ameliorating dystonia in X-linked dystonia parkinsonism (XDP), a disease that is usually refractive to medical therapy.

Objective: To determine the efficacy of GPi-DBS in a cohort of patients with XDP in a prospective study and identify predictors of postoperative outcomes.

Design, Setting, And Participants: This observational prospective cohort study enrolled patients in February 2013 and was completed in December 2014. Read More

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December 2018
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Label-Free Identification of Lymphocyte Subtypes Using Three-Dimensional Quantitative Phase Imaging and Machine Learning.

J Vis Exp 2018 Nov 19(141). Epub 2018 Nov 19.

Department of Physics, Korea Advanced Institute of Science and Technology; KAIST Institute for Health Science and Technology, Korea Advanced Institute of Science and Technology; Tomocube, Inc.;

We describe here a protocol for the label-free identification of lymphocyte subtypes using quantitative phase imaging and machine learning. Identification of lymphocyte subtypes is important for the study of immunology as well as diagnosis and treatment of various diseases. Currently, standard methods for classifying lymphocyte types rely on labeling specific membrane proteins via antigen-antibody reactions. Read More

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November 2018
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Multifunctional Polystyrene Core/Silica Shell Microparticles with Antifouling Properties for Bead-based Multiplexed and Quantitative Analysis.

ACS Appl Mater Interfaces 2018 Dec 3. Epub 2018 Dec 3.

Commercial bead-based assays are commonly built upon polystyrene particles. The polymeric carrier can be encoded with organic dyes and has ideal material properties for cytometric applications such as low density and high refractive index. However, functional groups are conventionally integrated during polymerization and subsequent modification is limited to the reactivity of those groups that have been introduced during the bead preparation step. Read More

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December 2018
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Differences of body height, axial length, and refractive error at different ages in Kumejima study.

Graefes Arch Clin Exp Ophthalmol 2018 Nov 30. Epub 2018 Nov 30.

Department of Ophthalmology, Kanto Central Hospital, Tokyo, Japan.

Purpose: To determine the relationships between the axial length (AL), refractive error (RE), and body height (BH) at different ages of a genetically-stable population in Kumejima, Japan.

Methods: Cross-sectional, population-based study. Residents of Kumejima who were ≥ 40-years old were studied. Read More

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November 2018
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Combined flanged intrascleral intraocular lens fixation with corneal transplant.

Am J Ophthalmol Case Rep 2019 Mar 10;13:1-5. Epub 2018 Nov 10.

Medical University of South Carolina, USA.

Purpose: To report clinical outcomes and surgical technique of flanged intrascleral intraocular lens fixation with double-needle combined with either penetrating keratoplasty (PKP) or ultrathin Descemet-stripping automated endothelial keratoplasty (UT-DSAEK).

Observations: Five patients underwent combined flanged intrascleral intraocular lens fixation with double-needle technique and keratoplasty. Three patients underwent triple procedure (open sky intrascleral intraocular lens fixation with double-needle and PKP) secondary to ocular trauma or a failed corneal transplant. Read More

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March 2019
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An assessment of variation in macular volume and RNFL thickness in myopes using OCT and their significance for early diagnosis of primary open-angle glaucoma.

Oman J Ophthalmol 2018 Sep-Dec;11(3):241-247

Senior Resident, Department of Ophthalmology, AIIMS, Raipur (CG), Chhattisgarh, India.

Purpose: An assessment of variation in Macular Volume and RNFL Thickness in myopes using OCT, and their significance for early diagnosis of Primary Open Angle Glaucoma(POAG).

Materials And Method: Total of 122 eyes of 61 Indian Myopic subjects of both sex and various age groups underwent retinal nerve fiber layer thickness, macular volume in 6mm analysis by Rtvue Avanti SD-OCT, Optovue Technology V6.1. Read More

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December 2018
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Impact of venting incision on graft detachment in Descemet stripping automated endothelial keratoplasty.

Oman J Ophthalmol 2018 Sep-Dec;11(3):237-240

Department of Vitreo-Retina, Shri Ganapati Netralaya, Jalna, Maharashtra, India.

Purpose: To evaluate the impact of venting incision on graft detachment in Descemet stripping automated endothelial keratoplasty (DSAEK).

Materials And Methods: Retrospective comparative study on DSAEK procedure performed with ( = 13) and without ( = 39) venting incision. Patients were treated with DSAEK for various causes of endothelial decompensation between February 2014 and April 2016. Read More

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December 2018