582 results match your criteria Reflux Laryngitis


The Effect of Upper Airway Ailments on Teachers' Experience of Vocal Fatigue.

J Voice 2020 Jul 2. Epub 2020 Jul 2.

Michigan State University, East Lansing, Michigan.

Background: Teachers have been found to have a higher than normal risk to develop voice disorders. One common symptom of voice problems among teachers is the report and occurrence of vocal fatigue, often associated with different individual, physical, environmental, and professional factors.

Aim: The aim of this study was to provide insight into the potential effect of sinus infections, laryngitis, colds, seasonal allergies, and reflux on reported vocal fatigue, as quantified by the Vocal Fatigue Index (VFI). Read More

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http://dx.doi.org/10.1016/j.jvoice.2020.05.024DOI Listing

Saliva Pepsin Concentration of Laryngopharyngeal Reflux Patients Is Influenced by Meals Consumed Before the Samples.

Laryngoscope 2020 Jun 8. Epub 2020 Jun 8.

Laryngopharyngeal Reflux Study Group of Young Otolaryngologists of the, International Federation of Oto-Rhino-Laryngological Societies, Paris, France.

Objectives/hypothesis: To assess the impact of diet on the saliva pepsin concentration of patients with laryngopharyngeal reflux (LPR).

Study Design: Non-controlled Prospective Study.

Methods: Patients with positive LPR regarding hypopharyngeal-esophageal impedance-pH monitoring (HEMII-pH) were enrolled from three European Hospitals. Read More

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http://dx.doi.org/10.1002/lary.28756DOI Listing

Reflux Sign Assessment; Statistical Issue on Reliability to Avoid Misinterpretation.

Authors:
Siamak Sabour

Ann Otol Rhinol Laryngol 2020 Jun 6:3489420931892. Epub 2020 Jun 6.

Department of Clinical Epidemiology, School of Health and Safety, Shahid Beheshti University of Medical Sciences, Tehran, I.R. Iran.

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http://dx.doi.org/10.1177/0003489420931892DOI Listing

Usefulness of Pep-Test for Laryngo-Pharyngeal Reflux: A Pilot Study in Primary Care.

Korean J Fam Med 2020 May 28. Epub 2020 May 28.

GIGA-CP (Italian Group for Primary Care Gastroenterology), Milan, Italy.

Background: Gastroesophageal reflux disease is a digestive disorder characterized by nausea, regurgitation, and heartburn. Gastroesophageal reflux is the primary cause of laryngeal symptoms, especially chronic posterior laryngitis. The best diagnostic test for this disease is esophageal impedance-pH monitoring; however, it is poorly employed owing to its high cost and invasiveness. Read More

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http://dx.doi.org/10.4082/kjfm.18.0207DOI Listing

Hypopharyngeal-Esophageal Impedance-pH Monitoring Profiles of Laryngopharyngeal Reflux Patients.

Laryngoscope 2020 May 21. Epub 2020 May 21.

Laryngopharyngeal Reflux Study Group of Young Otolaryngologists of the International Federation of Otorhinolaryngological Societies, Paris, France.

Objectives/hypothesis: To investigate the profile of patients with laryngopharyngeal reflux (LPR) at hypopharyngeal-esophageal multichannel intraluminal impedance-pH (HEMII-pH) monitoring and the relationship between hypopharyngeal-proximal reflux episodes (HREs) and saliva pepsin concentration.

Study Design: Prospective non-controlled.

Methods: Patients were recruited from three European hospitals from January 2018 to October 2019. Read More

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http://dx.doi.org/10.1002/lary.28736DOI Listing
May 2020
2.032 Impact Factor

Validation of the Brazilian Portuguese Version of the Reflux Finding Score.

J Voice 2020 Feb 10. Epub 2020 Feb 10.

Attending Physician Otolaryngology Division, Fleury Medicina e Saúde Diagnostic Laboratories, São Paulo, SP, Brazil.

Introduction: Laryngopharyngeal reflux (LPR) poses a diagnostic challenge. Clinical diagnosis, based on suggestive symptoms and laryngoscopic signs of inflammation, should be acceptable, as long as diligent differential diagnosis is sought. In order to minimize subjectivity, a number of diagnostic instruments have been proposed, being the most common the Reflux Symptom Index and the Reflux Finding Score (RFS). Read More

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http://dx.doi.org/10.1016/j.jvoice.2020.01.012DOI Listing
February 2020

Assessing the utility of non-surgical treatments in the management of vocal process granulomas.

J Laryngol Otol 2020 Jan 10;134(1):68-73. Epub 2020 Jan 10.

Department of Otolaryngology, University of Miami Miller School of Medicine, Florida, USA.

Objective: To determine whether patients would have equivalent or improved outcomes when receiving non-surgical management versus surgical removal for vocal process granulomas.

Methods: A chart review was performed for 53 adults with vocal process granulomas. All patients received baseline anti-reflux treatment consisting of twice-daily proton pump inhibitors and vocal hygiene education. Read More

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http://dx.doi.org/10.1017/S0022215119002524DOI Listing
January 2020

Leukoplakia or LPR: The Misdiagnosis of Laryngeal Tuberculosis.

Ear Nose Throat J 2019 Nov 29:145561319891264. Epub 2019 Nov 29.

Department of Otolaryngology, Jining No. 1 People's Hospital, Jining, Shandong, China.

Objective: The objective is to reduce the rates of misdiagnosis and inappropriate treatment of laryngeal tuberculosis (LTB).

Study Design: Retrospective case series.

Materials And Methods: Medical records of 3 histopathology-confirmed cases at a tertiary medical center from 2000 to 2018. Read More

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http://dx.doi.org/10.1177/0145561319891264DOI Listing
November 2019

Lung function parameters in patients with gastroesophageal reflux without respiratory symptoms: a case-control study.

Gastroenterol Hepatol Bed Bench 2019 ;12(4):287-291

Tuberculosis and Lung Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.

Aim: This research aimed to evaluate the effect of gastroesophageal reflux disease (GERD) on pulmonary volumes, airflows, and airway resistance in the patients without respiratory symptoms and compare them with the healthy subjects.

Background: GERD is the return of gastric content into the esophagus and beyond. GERD may play an essential role in the extraesophageal diseases, including chest pain, asthma, laryngitis, chronic cough, and sinusitis. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6820839PMC
January 2019

Validity and Reliability of the Reflux Sign Assessment.

Ann Otol Rhinol Laryngol 2020 Apr 15;129(4):313-325. Epub 2019 Nov 15.

Research Committee of the Young-Otolaryngologists of the International Federations of Oto-rhino-laryngological Societies (YO-IFOS).

Objective: To develop and validate the Reflux Sign Assessment (RSA), a clinical instrument evaluating the physical findings of laryngopharyngeal reflux (LPR).

Methods: A total of 106 patients completed a 3-month treatment based on the association of diet, pantoprazole, alginate, or magaldrate with the LPR characteristics (acid, nonacid, mixed). Forty-two asymptomatic individuals completed the study (control group). Read More

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http://dx.doi.org/10.1177/0003489419888947DOI Listing

Food Sensitivity and Laryngopharyngeal Reflux: Preliminary Observations.

J Voice 2019 Nov 1. Epub 2019 Nov 1.

Department of Otolaryngology - Head and Neck Surgery, Clinical Academic Specialties, Drexel University College of Medicine; Otolaryngology and Communication Science Research, Lankenau Institute for Medical Research, Philadelphia, Pennsylvania. Electronic address:

Reflux is an expensive, high prevalence disease that affects at least half of patients with laryngeal and voice disorders. Approaches to treatment of laryngopharyngeal reflux include medical, lifestyle, dietary, and surgical treatment options. We review four patients who had persistent reflux signs and symptoms on appropriate lifestyle including elevating head of bed and dietary modifications, as well as antacid, H2 receptor blockers, and proton pump inhibitor therapy, who improved substantially on specific food avoidance diets. Read More

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http://dx.doi.org/10.1016/j.jvoice.2019.09.005DOI Listing
November 2019

Patients with acid, high-fat and low-protein diet have higher laryngopharyngeal reflux episodes at the impedance-pH monitoring.

Eur Arch Otorhinolaryngol 2020 Feb 2;277(2):511-520. Epub 2019 Nov 2.

Laryngopharyngeal Reflux Study Group of Young-Otolaryngologists of the International Federations of Oto-Rhino-Laryngological Societies (YO-IFOS), Paris, France.

Objective: To assess the impact of diet on the occurrence of proximal reflux episodes at the multichannel intraluminal impedance-pH monitoring (MII-pH) in patients with laryngopharyngeal reflux (LPR).

Methods: Patients with LPR symptoms and findings were recruited from three European hospitals. The LPR diagnostic was confirmed through MII-pH and patients were benefited from gastrointestinal (GI) endoscopy. Read More

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http://dx.doi.org/10.1007/s00405-019-05711-2DOI Listing
February 2020

Vocal Characteristics of Patients With Morbid Obesity.

J Voice 2019 Oct 21. Epub 2019 Oct 21.

Department of Surgery, São Paulo State University (Unesp), Botucatu, Sao Paulo, Brazil.

Introduction: Obesity modifies vocal characteristics, causing abnormal fat deposition in the abdominal region and upper airways. For some authors the voice of the obese is not different from nonobese and the vocal symptoms are scarce; for others dysphonia in obese is reported by 70% of them and the voice becomes hoarse, breathy, and unstable.

Objective: To characterize the voice of patients with morbid obesity. Read More

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http://dx.doi.org/10.1016/j.jvoice.2019.09.012DOI Listing
October 2019
1 Read

Treatment of laryngopharyngeal reflux disease: A systematic review.

World J Clin Cases 2019 Oct;7(19):2995-3011

Laboratory of Anatomy and Cell Biology, Faculty of Medicine, UMONS Research Institute for Health Sciences and Technology, University of Mons, Mons 7000, Belgium.

Backgroung: For a long time, laryngopharyngeal reflux disease (LPRD) has been treated by proton pump inhibitors (PPIs) with an uncertain success rate.

Aim: To shed light the current therapeutic strategies used for LPRD in order to analysis the rationale in the LPRD treatment.

Methods: Three authors conducted a PubMed search to identify papers published between January 1990 and February 2019 about the treatment of LPRD. Read More

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http://dx.doi.org/10.12998/wjcc.v7.i19.2995DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6795731PMC
October 2019

Sensitivity, Specificity, and Reproducibility of the Brazilian Portuguese Version of the Reflux Symptom Index.

J Voice 2019 Oct 2. Epub 2019 Oct 2.

Otolaryngology Division, Fleury Medicina e Saúde, São Paulo, Brazil.

Introduction: The diagnosis of laryngopharyngeal reflux is controversial. There is currently no gold standard, so it relies mainly on suspicious clinical symptoms and videolaryngoscopic findings. Unfortunately these signs and symptoms are common to other causes of chronic laryngitis. Read More

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http://dx.doi.org/10.1016/j.jvoice.2019.08.012DOI Listing
October 2019
1 Read

Development of scores assessing the refluxogenic potential of diet of patients with laryngopharyngeal reflux.

Eur Arch Otorhinolaryngol 2019 Dec 12;276(12):3389-3404. Epub 2019 Sep 12.

Laryngopharyngeal Reflux Study Group of Young-Otolaryngologists of the International Federations of Oto-Rhino-Laryngological Societies (YO-IFOS), Paris, France.

Objective: To develop clinical tools assessing the refluxogenic potential of foods and beverages (F&B) consumed by patients with laryngopharyngeal reflux (LPR).

Methods: European experts of the LPR Study group of the Young-Otolaryngologists of the International Federation of Oto-rhino-laryngological societies were invited to identify the components of Western European F&B that would be associated with the development of LPR. Based on the list generated by experts, four authors conducted a systematic review to identify the F&B involved in the development of esophageal sphincter and motility dysfunctions, both mechanisms involved in the development of gastroesophageal reflux disease and LPR. Read More

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http://dx.doi.org/10.1007/s00405-019-05631-1DOI Listing
December 2019
1 Read

Saliva pepsin level of laryngopharyngeal reflux patients is not correlated with reflux episodes.

Laryngoscope 2020 May 28;130(5):1278-1281. Epub 2019 Aug 28.

Research Committee of the Young-Otolaryngologists of the International Federation of Oto-rhino-laryngological Societies (YO-IFOS), Poitiers, France.

Objective: To investigate the relationship between the laryngopharyngeal reflux (LPR) episodes at the multichannel intraluminal impedance-pH monitoring (MII-pH) and the concentration of pepsin in the saliva of LPR patients.

Methods: Patients with LPR were enrolled from the polyclinic of Poitiers, France. Patients benefited from 24-hour MII-pH that allowed a correlation study between reflux episodes and symptoms. Read More

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http://dx.doi.org/10.1002/lary.28260DOI Listing
May 2020
3 Reads

Can the Reflux Finding Score and Reflux Symptom Index Be Used to Evaluate the Severity of Esophagitis in Children?

J Voice 2019 Aug 23. Epub 2019 Aug 23.

Yeditepe University Medical Faculty, Pathology Department, Istanbul, Turkey.

Objectives: Laryngopharyngeal reflux (LPR), a growing issue in ear, nose, and throat (ENT) and pediatric medicine, is the backflow of stomach contents into the laryngopharynx. Patients present with frequent upper and/or lower respiratory tract infections and coughs, associated with acid- and pepsin-mediated injury to the mucosae of the larynx and pharynx. LPR is associated with rhinosinusitis, laryngitis, pneumonia, and asthma. Read More

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http://dx.doi.org/10.1016/j.jvoice.2019.07.023DOI Listing
August 2019
6 Reads

Laryngopharyngeal reflux and autonomic nerve dysfunction: what about stress?

Eur Arch Otorhinolaryngol 2019 Jul 19. Epub 2019 Jul 19.

Laryngopharyngeal Reflux Study Group of Young Otolaryngologists of International Federation of Otorhinolaryngological Societies (YO-IFOS), Paris, France.

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http://dx.doi.org/10.1007/s00405-019-05567-6DOI Listing
July 2019
6 Reads

Updates in the field of non-esophageal gastroesophageal reflux disorder.

Expert Rev Gastroenterol Hepatol 2019 Sep 22;13(9):827-838. Epub 2019 Jul 22.

Gastrointestinal Unit, Department of Surgery, Oncology and Gastroenterology, University of Padua , Padua , Italy.

: Gastroesophageal reflux disease (GERD) is one of the most prevalent conditions in Western Countries, normally presenting with heartburn and regurgitation. Extra-esophageal (EE) GERD manifestations, such as asthma, laryngitis, chronic cough and dental erosion, represent the most challenging aspects from diagnostic and therapeutic points of view because of their multifactorial pathogenesis and low response to proton pump inhibitors (PPIs). In fact, in the case of EE, other causes must by preventively excluded, but instrumental methods, such as upper gastrointestinal endoscopy and laryngoscopy, have low specificity and sensitivity as diagnostic tools. Read More

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http://dx.doi.org/10.1080/17474124.2019.1645593DOI Listing
September 2019
8 Reads

Awareness of European Otolaryngologists and General Practitioners Toward Laryngopharyngeal Reflux.

Ann Otol Rhinol Laryngol 2019 Nov 1;128(11):1030-1040. Epub 2019 Jul 1.

Laryngopharyngeal Reflux Study Group of Young-Otolaryngologists of the International Federations of Oto-rhino-laryngological Societies (YO-IFOS).

Objectives: To investigate the current trends in management of laryngopharyngeal reflux (LPR) among young European otolaryngologists and general practitioners (GP).

Methods: An international survey was sent to European general practitioners and all otolaryngologists under 45 years old from the 2017 IFOS meeting. This survey was conducted by the LPR Study Group of YO-IFOS (Young Otolaryngologists of the International Federation of Otolaryngological Societies). Read More

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http://journals.sagepub.com/doi/10.1177/0003489419858090
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http://dx.doi.org/10.1177/0003489419858090DOI Listing
November 2019
7 Reads

Changing Trends of Color of Different Laryngeal Regions in Laryngopharyngeal Reflux Disease.

Ear Nose Throat J 2019 Jun 2:145561319854745. Epub 2019 Jun 2.

2 Division of Otolaryngology-Head and Neck Surgery, Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.

Introduction: In our previous study, we demonstrated that there might be correlations between laryngopharyngeal reflux disorder and the hue value of laryngoscopic images. And we found that different regions of larynx have different hue values. It was hypothesized that the degree of inflammation varies between different laryngeal regions, due to an acid reflux pattern. Read More

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http://dx.doi.org/10.1177/0145561319854745DOI Listing
June 2019
22 Reads
0.881 Impact Factor

Clinical and Acoustical Voice Quality Evolutions Throughout Empirical Treatment for Laryngopharyngeal Reflux Disease According to Gender: A Preliminary Study.

Folia Phoniatr Logop 2019 May 27:1-10. Epub 2019 May 27.

Laboratory of Anatomy and Cell Biology, Faculty of Medicine, UMONS Research Institute for Health Sciences and Technology, University of Mons, Mons, Belgium.

Objective: To compare symptoms, signs, and acoustical voice quality changes throughout the 6-month course of empirical treatment between laryngopharyngeal reflux (LPR) males and females.

Materials And Methods: Forty clinically diagnosed LPR females and 40 males with a reflux finding score (RFS) >7 and a reflux symptom index (RSI) >13 were treated with pantoprazole and diet recommendations during 3 or 6 months according to their evolution. RSI, RFS, and acoustic parameters were assessed at baseline and 3 and 6 months posttreatment. Read More

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http://dx.doi.org/10.1159/000500085DOI Listing
May 2019
4 Reads

Validity and reliability of the reflux symptom score.

Laryngoscope 2020 Mar 14;130(3):E98-E107. Epub 2019 Apr 14.

Research Committee of the Young Otolaryngologists of the International Federation of Oto-Rhino-Laryngological Societies (YO-IFOS), Marseille, France.

Objectives/hypothesis: To develop and validate the Reflux Symptom Score (RSS), a self-administered patient-reported outcome questionnaire for patients with laryngopharyngeal reflux (LPR).

Study Design: Prospective controlled study.

Methods: A total of 113 patients with LPR were enrolled and treated with diet and 3 months of pantoprazole, alginate, and/or magaldrate depending on the LPR characteristics (acid, nonacid, or mixed). Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1002/lary.28017
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http://dx.doi.org/10.1002/lary.28017DOI Listing
March 2020
22 Reads

Perceptual, Aerodynamic, and Acoustic Characteristics of Voice Changes in Patients with Laryngopharyngeal Reflux Disease.

Ear Nose Throat J 2019 Jul 8;98(6):E44-E50. Epub 2019 Apr 8.

1 Laboratory of Anatomy and Cell Biology, Faculty of Medicine, UMONS Research Institute for Health Sciences and Technology, University of Mons (UMons), Mons, Belgium.

Laryngopharyngeal reflux (LPR) is an inflammatory condition suspected to be associated with dysphonia. In this study, we investigated multidimensional perceptual, aerodynamic, and acoustic voice changes in patients with clinically diagnosed LPR compared to healthy participants. We prospectively included 80 outpatients with Reflux Finding Score (RFS) >7 and Reflux Symptom Index (RSI) >13 from September 2013 to April 2016 and we compared clinical and voice quality assessments of these patients with 80 healthy participants. Read More

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http://dx.doi.org/10.1177/0145561319840830DOI Listing
July 2019
6 Reads

[Acute and chronic laryngitis in the subjects engaged in the voice and speech professions].

Vestn Otorinolaringol 2019 ;84(1):68-71

Saint-Petersburg Research Institute of Ear, Throat, Nose and Speech, Ministry of Health of the Russian Federation, Saint-Petersburg, Russia, 190013.

Laryngitis is one of the commonest causes of dysphonia in the subjects engaged in the voice and speech professions. This condition can be either associated with the professional activities or related to voice fatigue. It is a common practice to distinguish between acute and chronic forms of occupational laryngitis. Read More

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http://dx.doi.org/10.17116/otorino20198401168DOI Listing
July 2019
14 Reads

Risk factors associated with oral manifestations and oral health impact of gastro-oesophageal reflux disease: a multicentre, cross-sectional study in Pakistan.

BMJ Open 2019 03 30;9(3):e021458. Epub 2019 Mar 30.

Department of Prosthodontics and Implantology, King Faisal University, Al-Hasa, Saudi Arabia.

Objective: Gastro-oesophageal reflux disease (GORD) is a relatively common disorder and manifests with extraoesophageal symptoms, such as dental erosions (DE), cough, laryngitis, asthma, and oral soft- and hard-tissue pathologies. This study aimed (1) to identify oral soft and hard-tissue changes in patients with GORD and (2) to evaluate these oral changes as indices for assessing GORD and its severity.

Setting: This cross-sectional study was conducted at four major tertiary care government hospitals, in two metropolitan cities of Pakistan. Read More

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http://bmjopen.bmj.com/lookup/doi/10.1136/bmjopen-2017-02145
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http://dx.doi.org/10.1136/bmjopen-2017-021458DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6475213PMC
March 2019
26 Reads
2.063 Impact Factor

Natural history, pathophysiology and evaluation of gastroesophageal reflux disease.

Dis Mon 2020 Jan 22;66(1):100848. Epub 2019 Feb 22.

Division of Gastroenterology & Hepatology, The University of Texas Medical Branch, Galveston, TX, United States.

Gastroesophageal reflux disease (GERD) is one of the most common diseases encountered by both internists and gastroenterologists. GERD can cause a wide variety of symptoms ranging from heartburn and regurgitation to more atypical symptoms such as cough, chest pain, and hoarseness. The diagnosis is often times made on the basis of history and clinical symptomatology. Read More

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http://dx.doi.org/10.1016/j.disamonth.2019.02.001DOI Listing
January 2020
5 Reads
0.535 Impact Factor

Evaluation and Management of Laryngopharyngeal Reflux Disease: State of the Art Review.

Otolaryngol Head Neck Surg 2019 05 12;160(5):762-782. Epub 2019 Feb 12.

14 Division of Gastroenterology, Hepatology, Nutrition, Vanderbilt University Medical Center, Nashville, Tennessee, USA.

Objective: To review the current literature about the epidemiology, clinical presentation, diagnosis, and treatment of laryngopharyngeal reflux (LPR).

Data Sources: PubMed, Cochrane Library, and Scopus.

Methods: A comprehensive review of the literature on LPR epidemiology, clinical presentation, diagnosis, and treatment was conducted. Read More

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http://dx.doi.org/10.1177/0194599819827488DOI Listing
May 2019
27 Reads

[Application of reflux symptom index in diagnosis of allergic patients with laryngopharyngeal reflux].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Nov;32(22):1711-1713

Department of Otolaryngology, the Affiliated Hospital of Chengde Medical University, Chengde, 067000, China.

To explore the diagnostic value and optimal diagnostic threshold of reflux symptom index(RSI) in allergic patients with laryngopharyngeal reflux. All the adult allergic patients with respiratory tract symptoms completed the RSI with the consent of the patients. A total of 150 patients with RSI>13 were screened out. Read More

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http://www.cnki.net/kcms/doi/10.13201/j.issn.1001-1781.2018.
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http://dx.doi.org/10.13201/j.issn.1001-1781.2018.22.007DOI Listing
November 2018
19 Reads

Clinical outcomes of laryngopharyngeal reflux treatment: A systematic review and meta-analysis.

Laryngoscope 2019 05 30;129(5):1174-1187. Epub 2018 Dec 30.

Division of Gastroenterology, Hepatology, Nutrition, Vanderbilt University Medical Center, Nashville, Tennessee, U.S.A.

Objectives: To investigate the therapeutic benefit of proton pump inhibitors (PPIs) over placebo in patients with laryngopharyngeal reflux (LPR) and to analyze the epidemiological factors of heterogeneity in the literature.

Methods: An electronic literature search was conducted to identify articles published between 1990 and 2018 about clinical trials describing the efficiency of medical treatment(s) on LPR. First, a meta-analysis of placebo randomized controlled trials (RCTs) comparing PPIs versus placebo was conducted according to diet. Read More

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http://dx.doi.org/10.1002/lary.27591DOI Listing
May 2019
7 Reads

Establishment of a novel and effective reflux laryngitis model in rabbits: a preliminary study.

Eur Arch Otorhinolaryngol 2019 Jan 10;276(1):175-183. Epub 2018 Dec 10.

The Department of Otolaryngology-Head and Neck Surgery, Eye, Ear, Nose, and Throat Hospital of Fudan University, 83 Fenyang Road, Shanghai, 200030, China.

Purpose: To establish a novel and effective reflux model with a modified nasogastric aspiration tube and to investigate the association between different types of nasogastric aspiration tubes and reflux laryngitis, we conducted this study.

Methods: Thirty-eight healthy New Zealand albino rabbits (2.5-3. Read More

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http://link.springer.com/10.1007/s00405-018-5234-7
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http://dx.doi.org/10.1007/s00405-018-5234-7DOI Listing
January 2019
38 Reads

Laryngopharyngeal reflux and benign lesions of the vocal folds.

Eur Arch Otorhinolaryngol 2019 Jan 21;276(1):277-278. Epub 2018 Nov 21.

Department of Anatomy and Experimental Oncology, Mons School of Medicine, UMONS Research Institute for Health Sciences and Technology, University of Mons (UMons), Mons, Belgium.

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http://dx.doi.org/10.1007/s00405-018-5217-8DOI Listing
January 2019
50 Reads

[Vocal Changes and Laryngeal Modifications in the Elderly (Presbyphonia and Presbylarynx)].

Laryngorhinootologie 2018 Nov 7;97(11):772-776. Epub 2018 Nov 7.

In about 20 % of the population older than 60 years of age, voice problems (presbyphonia) are manifest, often combined with hearing deficits (presbyacusis), swallowing disorders (presbyphagia), dizziness (presbyvertigo) and/or impaired vision (presbyopia).The singing voice is afflicted more often, earlier and more severely than the speaking voice. But it is not just the vocal quality and capacity that are affected. Read More

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http://dx.doi.org/10.1055/a-0652-6758DOI Listing
November 2018
17 Reads

ARE THE PERSISTENT SYMPTOMS TO PROTON PUMP INHIBITOR THERAPY DUE TO REFRACTORY GASTROESOPHAGEAL REFLUX DISEASE OR TO OTHER DISORDERS?

Arq Gastroenterol 2018 Nov 4;55Suppl 1(Suppl 1):85-91. Epub 2018 Oct 4.

Universidade de São Paulo, Faculdade de Medicina, Hospital das Clínicas, Departamento de Gastroenterologia, São Paulo, SP, Brasil.

Background: Gastroesophageal reflux disease (GERD) is a clinical condition that develops when the reflux of stomach contents causes troublesome symptoms and/or complications. Transient lower esophageal sphincter relaxation is the main pathophysiological mechanism of GERD. Symptoms and complications can be related to the reflux of gastric contents into the esophagus, oral cavity, larynx and/or the lung. Read More

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http://dx.doi.org/10.1590/S0004-2803.201800000-48DOI Listing
November 2018
11 Reads

Voice Quality as Therapeutic Outcome in Laryngopharyngeal Reflux Disease: A Prospective Cohort Study.

J Voice 2020 Jan 13;34(1):112-120. Epub 2018 Sep 13.

Laboratory of Anatomy and Cell Biology, Faculty of Medicine, UMONS Research Institute for Health Sciences and Technology, University of Mons (UMons), Mons, Belgium; Department of Otorhinolaryngology and Head and Neck Surgery, RHMS Baudour, EpiCURA Hospital, Baudour, Belgium; Department of Otorhinolaryngology and Head and Neck Surgery, Faculté de medicine, CHU Saint-Pierre, Université Libre de Bruxelles, Bruxelles, Belgium.

Purpose: To study the usefulness of voice quality as therapeutic outcome in laryngopharyngeal reflux disease.

Material And Methods: A total of 80 patients with reflux finding score (RFS) > 7 and reflux symptom index (RSI) > 13 were treated with pantoprazole, diet, and lifestyle recommendations for 3 months. The therapeutic effectiveness was assessed with RSI; RFS; Voice Handicap Index; blinded Grade, Roughness, Breathiness, Asthenia, Strain, and Instability (GRBASI); aerodynamic and a panel of acoustic measurements before and after treatment. Read More

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http://dx.doi.org/10.1016/j.jvoice.2018.08.018DOI Listing
January 2020
14 Reads

The development of new clinical instruments in laryngopharyngeal reflux disease: The international project of young otolaryngologists of the International Federation of Oto-rhino-laryngological Societies.

Eur Ann Otorhinolaryngol Head Neck Dis 2018 Sep 28;135(5S):S85-S91. Epub 2018 Aug 28.

Laryngopharyngeal Reflux Study Group of Young Otolaryngologists of International Federation of Oto-rhino-laryngological Societies, Belgium; Department of Anatomy and Experimental Oncology, Mons School of Medicine, UMONS Research Institute for Health Sciences and Technology, University of Mons (UMons), Mons, Belgium; Department of Otorhinolaryngology and Head and Neck Surgery, CHU Saint-Pierre, Université Libre de Bruxelles, School of Medicine, Brussels, Belgium.

Introduction: To analyze the epidemiological characteristics of placebo controlled randomized trials (RCTs) that evaluated the effectiveness of medical treatments over placebo in laryngopharyngeal reflux (LPR).

Material And Methods: PubMed, Cochrane database, and Scopus were assessed for subject headings using the PRISMA recommendations. Placebo RCTs published between 1990 and 2018 describing clinical evolution throughout LPR treatment were extracted and analyzed for evidence-based level, number of patients, inclusion and exclusion criteria, gender, age, symptoms and signs used as therapeutic outcomes, and treatment schemes. Read More

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http://dx.doi.org/10.1016/j.anorl.2018.05.013DOI Listing
September 2018
9 Reads

Characteristics and Voice Outcomes of Ulcerative Laryngitis.

J Voice 2020 Jan 29;34(1):105-111. Epub 2018 Aug 29.

University of California-San Francisco, Department of Otolaryngology-Head and Neck Surgery, San Francisco, California.

Objectives: Ulcerative laryngitis (UL) is challenging in terms of treatment and patient counseling, with few reports in the literature. This study describes UL patients and their clinical course including detailed voice and stroboscopic outcomes after treatment which have not been described in previous literature.

Methods: Single-institution, retrospective review of 23 UL patients. Read More

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http://dx.doi.org/10.1016/j.jvoice.2018.07.021DOI Listing
January 2020
29 Reads

Laryngopharyngeal reflux disease in singers: Pathophysiology, clinical findings and perspectives of a new patient-reported outcome instrument.

Eur Ann Otorhinolaryngol Head Neck Dis 2019 Jun 27;136(3S):S39-S43. Epub 2018 Aug 27.

Laboratory of Phonetics, Faculty of Psychology, Research Institute for Language Sciences and Technology, University of Mons (UMons), Mons, Belgium; Laryngopharyngeal Reflux Study Group of Young Otolaryngologists of International Federation of Oto-rhino-laryngological Societies, Paris, France; Department of Otorhinolaryngology and Head and Neck Surgery, CHU de Liège, Faculty of Medicine, University of Liège, Liège, Belgium.

Purpose Of Review: Laryngopharyngeal reflux (LPR) is an inflammatory disease associated with the development of voice disorder and vocal fold lesions. The occurrence of LPR in professional voice users as singers can have a dramatic impact of daily life. The aims of this paper is to review the current literature about the pathophysiological mechanisms underlying the development of voice disorder, especially in singers, and to propose a new patient-reported outcome instrument to assess complaints of these patients. Read More

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http://dx.doi.org/10.1016/j.anorl.2018.08.008DOI Listing
June 2019
10 Reads

Safety and utility of direct laryngoscopy and bronchoscopy in patients hospitalized with croup.

Ear Nose Throat J 2018 Aug;97(8):E25-E30

Texas ENT Specialists, 23920 Katy Fwy., Suite 430, Katy, TX 77494, USA.

Acute croup is a common admitting diagnosis for pediatric patients. If a patient is not responding to medical management for presumed croup, the otolaryngology team is occasionally consulted for direct laryngoscopy and bronchoscopy (DLB) to rule out tracheitis or another airway pathology. We conducted a study to determine if inpatient DLB in acute croup is safe and efficacious and to correlate preoperative vital signs with intraoperative findings. Read More

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http://dx.doi.org/10.1177/014556131809700805DOI Listing
August 2018
9 Reads

Gaviscon® Advance alone versus co-prescription of Gaviscon® Advance and proton pump inhibitors in the treatment of laryngopharyngeal reflux.

Eur Arch Otorhinolaryngol 2018 Oct 30;275(10):2515-2521. Epub 2018 Jul 30.

Department of Otorhinolaryngology - Head and Neck Surgery, Warrington and Halton Hospitals NHS Foundation Trust, Lovely Lane, Warrington, WA5 1QG, UK.

Objectives: Management of laryngopharyngeal reflux (LPR) typically comprises alginates and proton pump inhibitors (PPIs) alone or in combination, yet evidence to support any particular treatment regimen is lacking. We sought to evaluate the efficacy of Gaviscon® Advance alone versus co-prescription with a PPI in treating LPR.

Methods: One hundred consecutive LPR patients with a reflux symptom index (RSI) score > 10 attending our joint voice clinic (JVC) were studied prospectively. Read More

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http://dx.doi.org/10.1007/s00405-018-5079-0DOI Listing
October 2018
54 Reads

Impact of Laryngopharyngeal Reflux on Subjective, Aerodynamic, and Acoustic Voice Assessments of Responder and Nonresponder Patients.

J Voice 2019 Nov 27;33(6):929-939. Epub 2018 Jul 27.

Laboratory of Anatomy and Cell Biology, Faculty of Medicine, UMONS Research Institute for Health Sciences and Technology, University of Mons (UMons), Mons, Belgium; Department of Otorhinolaryngology and Head and Neck Surgery, RHMS Baudour, EpiCURA Hospital, Baudour, Belgium.

Objective: To investigate the usefulness of voice quality assessment as a treatment outcome in responder and nonresponder patients with laryngopharyngeal reflux (LPR).

Material And Methods: Eighty clinically diagnosed LPR patients with reflux finding score (RFS) > 7 and reflux symptom index (RSI) > 13 were treated with pantoprazole, lifestyle changes, and diet recommendations for three months. RSI; RFS; Voice Handicap Index; blinded Grade, Roughness, Breathiness, Asthenia, Strain, and Instability; aerodynamic and acoustic measurements were assessed at baseline and after treatment. Read More

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http://dx.doi.org/10.1016/j.jvoice.2018.05.014DOI Listing
November 2019
33 Reads

Evaluation of gastroesophageal reflux disease.

Updates Surg 2018 Sep 23;70(3):309-313. Epub 2018 Jul 23.

Department of Medicine and Surgery, University of North Carolina School of Medicine, Chapel Hill, NC, USA.

Patients with gastroesophageal reflux disease (GERD) may present with a variety of symptoms, including heartburn, regurgitation, dysphagia, chronic cough, laryngitis, or even asthma. Therefore, the clinical presentation of GERD varies among individuals and conversely symptoms not always correspond to the presence of actual reflux. For that reason, the diagnosis poses certain challenges to the physician. Read More

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http://dx.doi.org/10.1007/s13304-018-0563-zDOI Listing
September 2018
18 Reads

Eosinophilic granulomatosis with polyangiitis and laryngeal involvement: review of the literature and a cross-sectional prospective experience.

J Laryngol Otol 2018 Jul 11;132(7):619-623. Epub 2018 Jun 11.

Rheumatology Unit,University of Pisa,Italy.

Background: Eosinophilic granulomatosis with polyangiitis and granulomatosis with polyangiitis show variable otorhinolaryngological involvement. Up to 14 per cent of granulomatosis with polyangiitis patients have subglottis involvement; little is known about the laryngeal involvement in eosinophilic granulomatosis with polyangiitis.

Method: A literature review was conducted, together with a prospective cross-sectional analysis of 43 eosinophilic granulomatosis with polyangiitis patients. Read More

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http://dx.doi.org/10.1017/S0022215118000737DOI Listing
July 2018
10 Reads

Medical Therapy of Gastroesophageal Reflux Disease Beyond Proton Pump Inhibitors: Where Are We Heading?

Authors:
Herbert Koop

Visc Med 2018 Apr 29;34(2):110-115. Epub 2018 Mar 29.

formerly Department of General Internal Medicine and Gastroenterology, Helios Klinikum Berlin-Buch, Berlin, Germany.

Proton pump inhibitors (PPI) have greatly improved the treatment of gastroesophageal reflux disease. However, recent investigations have revealed that reflux symptoms persist in a substantial number of patients. Therefore, treatment strategies beyond PPI are urgently required. Read More

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http://dx.doi.org/10.1159/000486692DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5981673PMC
April 2018
7 Reads

Change of signs, symptoms and voice quality evaluations throughout a 3- to 6-month empirical treatment for laryngopharyngeal reflux disease.

Clin Otolaryngol 2018 10 5;43(5):1273-1282. Epub 2018 Jun 5.

Faculty of Medicine, Laboratory of Anatomy and Cell Biology, UMONS Research Institute for Health Sciences and Technology, University of Mons (UMons), Mons, Belgium.

Objective: To assess the usefulness of voice quality measurements as a treatment outcome in patients with laryngopharyngeal reflux (LPR)-related symptoms.

Design: Prospective uncontrolled multi-centre study.

Material And Methods: A total of 80 clinically diagnosed LPR patients with a reflux finding score (RFS)>7 and a reflux symptom index (RSI)>13 were treated with pantoprazole and diet recommendations during 3 or 6 months, according to their evolution. Read More

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http://dx.doi.org/10.1111/coa.13140DOI Listing
October 2018
4 Reads

Correlation between Allergic Rhinitis and Laryngopharyngeal Reflux.

Biomed Res Int 2018 22;2018:2951928. Epub 2018 Mar 22.

Department of Otolaryngology, Head & Neck Surgery, Prince Sultan Medical Military City, Riyadh, Saudi Arabia.

Background And Objectives: Laryngopharyngeal reflux (LPR) exhibits nonspecific clinical presentations, and these symptoms may be associated with other conditions such as allergies, including allergic rhinitis and laryngitis. However, there is a gap in the literature regarding the correlation of laryngopharyngeal reflux with allergic rhinitis/laryngitis. Hence, the aim of this study is to explore the correlation between these two conditions. Read More

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http://dx.doi.org/10.1155/2018/2951928DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5885348PMC
October 2018
6 Reads

The Effects of Reflux on the Elderly: The Problems with Medications and Interventions.

Otolaryngol Clin North Am 2018 Aug 24;51(4):779-787. Epub 2018 Apr 24.

Department of Head and Neck Surgery, UCLA Voice Center for Medicine and the Arts, 200 Medical Plaza, Suite 550, Los Angeles, CA 90095, USA. Electronic address:

Reflux-related complaints are a frequent cause for otolaryngology consultation, and with the aging population the concerns specific to the elderly reflux patient are critical. The elderly patient is less likely to present with typical laryngopharyngeal reflux (LPR) or gastroesophageal reflux disease (GERD) symptoms. Importantly, elderly patients typically have objective findings more severe than the level of the symptoms. Read More

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http://dx.doi.org/10.1016/j.otc.2018.03.007DOI Listing
August 2018
8 Reads