607 results match your criteria Reflux Laryngitis


The role of imaging in the evaluation of hoarseness: A review.

Authors:
Vikas Jain

J Neuroimaging 2021 May 20. Epub 2021 May 20.

Radiology Department, MetroHealth Medical Center, Case Western Reserve University, Cleveland, Ohio, USA.

Hoarseness is a common symptom indicating an abnormal change in the quality of voice and has a lifetime prevalence of around 30%. There are multiple causes of hoarseness, ranging from acute laryngitis, chronic laryngitis, laryngopharyngeal reflux, functional dysphonia due to vocal overuse or abuse, vocal cord paralysis (VCP), to various pathologies and masses in the larynx. A detailed history and thorough physical examination, and in many cases, laryngoscopy by a clinician are the initial steps in its management. Read More

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Application of High Speed Digital Imaging (HSDI) technique in the diagnosis of dysphonia in patients with laryngopharyngeal reflux disease (LPR).

Otolaryngol Pol 2021 Feb;75(3):1-5

Department of Clinical Phonoaudiology and Speech Therapy, Medical University of Bialystok, Poland.

Introduction Gastroesophageal reflux disease (GERD) may cause extra-esophageal complications, including laryngopharyngeal reflux disease (LPR). It is caused by morphological changes in the laryngeal mucosa due to the regurgitation of gastric contents. Laryngopharyngeal reflux has a wide symptomatology. Read More

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February 2021

Involvement of Laryngopharyngeal Reflux in Ocular Diseases: A State-of-the-Art Review.

J Voice 2021 Apr 10. Epub 2021 Apr 10.

Anatomy and Cell Biology Department, Faculty of Medicine, Research Institute for Health Sciences and Technology, University of Mons (UMONS), 7000, Mons, Belgium; Pediatrics Department. Complexo Hospitalario Universitario A Coruña (CHUAC), 15006, A Coruña, Galicia, Spain.

Background: Laryngopharyngeal reflux-associated symptoms embrace a wide variety of head and neck manifestations. Its participation in eye disorders has recently been postulated, and there is currently no consensus in this regard. The aim of this manuscript is to review the role of reflux in the development of ocular signs and symptoms, and its physio-pathological mechanisms. Read More

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Dysphonia in Performers: Prevalence of Vocal Lesions and Voice Emergencies in a Private Otorhinolaryngology Practice.

J Voice 2021 Mar 27. Epub 2021 Mar 27.

Department of Otolaryngology-Head and Neck Surgery, State University of Rio de Janeiro Rio de Janeiro, Rio de Janeiro - RJ, Brazil.

Objective: To determine the prevalence of abnormal laryngeal findings during videostroboscopy in performers presenting to clinic or when having an acute vocal emergency.

Study Design: Retrospective study of professional singers and actors who presented for a vocal evaluation.

Subjects And Methods: A chart review of singers or professional actors who presented in a private otorhinolaryngology clinic between 2014 and 2016. Read More

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Impact of subspecialty training on management of laryngopharyngeal reflux: results of a worldwide survey.

Eur Arch Otorhinolaryngol 2021 Jun 27;278(6):1933-1943. Epub 2021 Feb 27.

Division of Laryngology and the Professional Voice Department of Otolaryngology, Communication Science Medical College of Wisconsin, Milwaukee, WI, USA.

Objective: To study the management of laryngopharyngeal reflux (LPR) among the subspecialties of practicing otolaryngology-head and neck surgeons and their trainees.

Methods: A survey was sent to over 8000 otolaryngologists (OTOHNS) over 65 countries, utilizing membership lists of participating otolaryngological societies. The outcomes were answers to questions regarding LPR knowledge and practice patterns, and included queries about its definition, prevalence, clinical presentation, diagnosis, and treatment. Read More

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Impedance-pH monitoring profile of patients with reflux and obstructive sleep apnea syndrome: A controlled study.

Clin Otolaryngol 2021 Jul 24;46(4):816-822. Epub 2021 May 24.

Laryngopharyngeal Reflux Study Group of Young-Otolaryngologists of the International Federations of Oto-rhino-laryngological Societies (YO-IFOS), Paris, France.

Objective: To study the profile of patients with obstructive sleep apnoea syndrome (OSAS) and laryngopharyngeal reflux (LPR) at the hypopharyngeal-oesophageal multichannel intraluminal impedance-pH monitoring (HEMII-pH) and to compare their reflux findings with LPR patients without OSAS.

Design: Prospective controlled study.

Methods: Patients with LPR and OSAS were prospectively recruited from August 2019 to June 2020. Read More

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Reflux clinic: proof-of-concept of a Multidisciplinary European Clinic.

Eur Arch Otorhinolaryngol 2021 05 23;278(5):1713-1716. Epub 2021 Feb 23.

Laryngopharyngeal Reflux Study Group of Young-Otolaryngologists of the International Federations of Oto-Rhino-Laryngological Societies (YO-IFOS), Paris, France.

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Otolaryngeal and Oropharyngeal Conditions: Dysphonia.

Authors:
Robert L Gauer

FP Essent 2021 Feb;501:11-16

Uniformed Services University F Edward Hébert School of Medicine Department of Family Medicine, 4301 Jones Bridge Road A1038, Bethesda, MD 20814-4799.

Dysphonia is any alteration of voice quality or vocal effort that impairs communication and affects quality of life. In patients with dysphonia, voice qualities often are described as tremulous, hoarse, strained, or raspy, with altered pitch, breathiness, or vocal fatigue. Dysphonia is a sign of an underlying disease process. Read More

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February 2021

Fifteen-minute consultation: Guide to paediatric voice disorders.

Arch Dis Child Educ Pract Ed 2021 Feb 12. Epub 2021 Feb 12.

Department of Paediatric ENT, Noah's Ark Children's Hospital for Wales, Cardiff, UK.

Paediatric voice disorders in the normal paediatric population ranges from 6% to 20%. We outline the important features in the initial evaluation of a persistent altered cry or voice in children and highlight the subsequent management currently used by ear, nose and throat (ENT) surgeons and speech and language therapists (SLTs). It is important to appreciate that there are stark differences between a child and adult larynx due to anatomical and physiological changes during development. Read More

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February 2021

The efficacy of a personalised treatment depending on the characteristics of reflux at multichannel intraluminal impedance-pH monitoring in patients with acid, non-acid and mixed laryngopharyngeal reflux.

Clin Otolaryngol 2021 May 10;46(3):602-613. Epub 2021 Feb 10.

Laryngopharyngeal Reflux Study Group of Young-Otolaryngologists of the International Federations of Oto-rhino-laryngological Societies (YO-IFOS), Paris, France.

Objective: To assess the evolution of symptoms and findings of laryngopharyngeal reflux (LPR) patients according to the type of reflux (acid, non-acid, mixed and gastro-oesophageal (GERD)).

Design: Prospective uncontrolled multicentre study.

Methods: One hundred and six patients with LPR have been recruited from 3 European Hospitals. Read More

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Does Pepsin Saliva Concentration (Peptest™) Predict the Therapeutic Response of Laryngopharyngeal Reflux Patients?

Ann Otol Rhinol Laryngol 2021 Jan 19:3489420986347. Epub 2021 Jan 19.

Laryngopharyngeal Reflux Study Group of Young-Otolaryngologists of the International Federations of Oto-rhino-laryngological Societies (YO-IFOS), Paris, France.

Objective: To study the profile and the therapeutic response of patients with laryngopharyngeal reflux (LPR) at the hypopharyngeal-esophageal multichannel intraluminal impedance-pH monitoring (HEMII-pH) according to the initial pepsin saliva concentration.

Methods: From January 2018 to January 2020, patients with positive LPR diagnosis at the HEMII-pH were consecutively recruited from 3 European Hospitals. Saliva pepsin concentration (Peptest™) was measured during the HEMII-pH testing period and patients were classified into 2 groups: negative versus positive Peptest. Read More

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January 2021

Management of laryngopharyngeal reflux in Brazil: a national survey.

Braz J Otorhinolaryngol 2020 Dec 29. Epub 2020 Dec 29.

Universidade de São Paulo, Faculdade de Medicina, Hospital das Clínicas, Departamento de Otorrinolaringologia, São Paulo, SP, Brazil. Electronic address:

Introduction: Studies assessing the management of laryngopharyngeal reflux by otolaryngologists have reported an important heterogeneity regarding the definition, diagnosis, and treatment, which leads to discrepancies in the management of the patient. Information about the current knowledge and practices of Brazilian otolaryngologists in laryngopharyngeal reflux is lacking.

Objective: To investigate the trends in management of laryngopharyngeal reflux disease among Brazilian otolaryngologists. Read More

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December 2020

Allergic Rhinitis and Laryngeal Pathology: Real-World Evidence.

Healthcare (Basel) 2021 Jan 3;9(1). Epub 2021 Jan 3.

College of Medicine, Chang Gung University, Taoyuan 333, Taiwan.

Allergic rhinitis (AR) is correlated with diseases including allergic laryngitis, chronic obstructive pulmonary disease (COPD), asthma, and chronic rhinosinusitis (CRS). The unified airway model suggests that inflammation can spread in both lower and upper respiratory tracts. Moreover, some voice problems-laryngeal edema, dysphonia, and vocal nodules-have been associated with AR. Read More

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January 2021

Histopathology of laryngomalacia.

Acta Otolaryngol 2021 Jan 14;141(1):85-88. Epub 2020 Oct 14.

Ear, Nose and Throat Department, Leeds Teaching Hospitals NHS Trust, Leeds, UK.

Background: Laryngomalacia is the commonest laryngeal anomaly and cause of stridor in children. Although most cases are self-limiting, failure to thrive, hypoxaemia or significant apnoeic episodes may warrant surgical intervention in the form of aryepiglottoplasty. Opinion is divided as to the pathophysiological mechanisms involved in the disease process. Read More

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January 2021

Pump Proton and Laryngeal H/K ATPases.

Int J Gen Med 2020 14;13:1509-1514. Epub 2020 Dec 14.

Department of Otolaryngology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang 310003, People's Republic of China.

Purpose: The presence of extra-gastric H/K ATPases may explain the clinically significant effect of proton pump inhibitor (PPI) pharmacotherapy in patients with chronic laryngitis related to laryngopharyngeal reflux disease (LPRD) but without gastroesophageal reflux disease (GERD) symptoms. Given the need for a better understanding of GERD and LPRD, we review the various proton pumps with respect to their classification, function, and distribution. We then consider the potential role of the laryngeal H/K ATPase pump in LPRD. Read More

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December 2020

Review of management of laryngopharyngeal reflux disease.

Eur Ann Otorhinolaryngol Head Neck Dis 2020 Nov 27. Epub 2020 Nov 27.

Laryngopharyngeal Reflux Study Group of Young-Otolaryngologists of the International Federations of Oto-rhino-laryngological Societies (YO-IFOS), Paris, France; Department of Anatomy and Experimental Oncology, Mons School of Medicine, UMONS Research Institute for Health Sciences and Technology, University of Mons (UMons), Mons, Belgium.

This review was conducted according to the Patient/problem Intervention Comparison Outcome (PICO) Statements. Some studies reported that 10-30% of patients consulting in ENT come with presenting symptoms of laryngopharyngeal reflux (LPR), but the exact prevalence of LPR is still unknown. Management has not changed in 20 years despite a significant increase in the number of publications on epidemiology, clinical presentation, diagnosis and treatment. Read More

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November 2020

Management of Laryngopharyngeal Reflux Around the World: An International Study.

Laryngoscope 2021 05 17;131(5):E1589-E1597. Epub 2020 Nov 17.

Laryngopharyngeal Reflux Study Group of Young-Otolaryngologists of the International Federations of Oto-rhino-laryngological Societies (YO-IFOS), Paris, France.

Objective: To investigate worldwide practices of otolaryngologists in the management of laryngopharyngeal reflux (LPR).

Methods: An online survey was sent on the management of LPR to members of many otolaryngological societies. The following aspects were evaluated: LPR definition, prevalence, clinical presentation, diagnosis, and treatment. Read More

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Extra-Esophageal Presentation of Gastroesophageal Reflux Disease: 2020 Update.

J Clin Med 2020 Aug 7;9(8). Epub 2020 Aug 7.

Unit of Gastroenterology, Città della Salute e della Scienza Hospital, C.so Bramante 88, 10126 Turin, Italy.

Gastroesophageal reflux disease (GERD) is defined by the presence of symptoms induced by the reflux of the stomach contents into the esophagus. Although clinical manifestations of GERD typically involve the esophagus, extra-esophageal manifestations are widespread and less known. In this review, we discuss extra-esophageal manifestations of GERD, focusing on clinical presentations, diagnosis, and treatment. Read More

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Changes of Laryngeal and Extralaryngeal Symptoms and Findings in Laryngopharyngeal Reflux Patients.

Laryngoscope 2021 06 5;131(6):1332-1342. Epub 2020 Aug 5.

Laryngopharyngeal Reflux Study Group of Young-Otolaryngologists of the International Federations of Oto-rhino-laryngological Societies (YO-IFOS), Paris, France.

Objectives/hypothesis: To assess the evolution of laryngeal and extralaryngeal symptoms and findings of laryngopharyngeal reflux (LPR) throughout a 3-month to 9-month treatment.

Study Design: Prospective Controlled Study.

Methods: One hundred twenty-seven LPR patients and 123 healthy individuals were enrolled from four European hospitals. Read More

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Specifics and diagnostic procedure in reflux-related dysphonia.

Wiad Lek 2020 ;73(4):814-817

Department of Clinical Phonoaudiology and Speech Therapy, Medical University Of Bialystok, Bialystok, Poland.

Voice is a work tool for many professional groups. Currently, cases of dysphonia of multiple origin consist a growing issue. Voice disorders may result from disturbed voice production process, congenital defects, post-traumatic conditions, chronic diseases or hormonal disorders. Read More

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Development and Validation of the Short Version of the Reflux Symptom Score: Reflux Symptom Score-12.

Otolaryngol Head Neck Surg 2021 01 21;164(1):166-174. Epub 2020 Jul 21.

Research Committee of the Young Otolaryngologists, International Federations of ORL Societies, Paris, France.

Objective: To develop and validate a short version of the Reflux Symptom Score-the 12-question Reflux Symptom Score-12 (RSS-12)-for patients with laryngopharyngeal reflux disease (LPR).

Study Design: Prospective study.

Setting: Multicenter academic hospitals. Read More

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January 2021

The Effect of Upper Airway Ailments on Teachers' Experience of Vocal Fatigue.

J Voice 2020 Jul 2. Epub 2020 Jul 2.

Michigan State University, East Lansing, Michigan.

Background: Teachers have been found to have a higher than normal risk to develop voice disorders. One common symptom of voice problems among teachers is the report and occurrence of vocal fatigue, often associated with different individual, physical, environmental, and professional factors.

Aim: The aim of this study was to provide insight into the potential effect of sinus infections, laryngitis, colds, seasonal allergies, and reflux on reported vocal fatigue, as quantified by the Vocal Fatigue Index (VFI). Read More

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Involvement of Laryngopharyngeal Reflux in Select Nonfunctional Laryngeal Diseases: A Systematic Review.

Otolaryngol Head Neck Surg 2021 01 23;164(1):37-48. Epub 2020 Jun 23.

Department of Otolaryngology-Head and Neck Surgery, Harvard Medical School, Boston, Massachusetts, USA.

Objectives: To investigate the existing published evidence supporting the role of laryngopharyngeal reflux (LPR) in the development of the select nonfunctional laryngeal diseases of laryngotracheal stenosis, granuloma, leukoplakia, and laryngeal infections.

Data Sources: PubMed, Cochrane Library, and Scopus.

Review Methods: A systematic review was performed by 3 independent investigators for studies providing information about the prevalence and role of LPR in the development of laryngotracheal stenosis, granuloma, leukoplakia, and laryngeal infections. Read More

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January 2021

Saliva Pepsin Concentration of Laryngopharyngeal Reflux Patients Is Influenced by Meals Consumed Before the Samples.

Laryngoscope 2021 02 8;131(2):350-359. Epub 2020 Jun 8.

Laryngopharyngeal Reflux Study Group of Young Otolaryngologists of the, International Federation of Oto-Rhino-Laryngological Societies, Paris, France.

Objectives/hypothesis: To assess the impact of diet on the saliva pepsin concentration of patients with laryngopharyngeal reflux (LPR).

Study Design: Non-controlled Prospective Study.

Methods: Patients with positive LPR regarding hypopharyngeal-esophageal impedance-pH monitoring (HEMII-pH) were enrolled from three European Hospitals. Read More

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February 2021

Reflux Sign Assessment; Statistical Issue on Reliability to Avoid Misinterpretation.

Authors:
Siamak Sabour

Ann Otol Rhinol Laryngol 2020 Nov 6;129(11):1144-1145. Epub 2020 Jun 6.

Department of Clinical Epidemiology, School of Health and Safety, Shahid Beheshti University of Medical Sciences, Tehran, I.R. Iran.

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November 2020

Usefulness of Pep-Test for Laryngo-Pharyngeal Reflux: A Pilot Study in Primary Care.

Korean J Fam Med 2020 Jul 28;41(4):250-255. Epub 2020 May 28.

GIGA-CP (Italian Group for Primary Care Gastroenterology), Milan, Italy.

Background: Gastroesophageal reflux disease is a digestive disorder characterized by nausea, regurgitation, and heartburn. Gastroesophageal reflux is the primary cause of laryngeal symptoms, especially chronic posterior laryngitis. The best diagnostic test for this disease is esophageal impedance-pH monitoring; however, it is poorly employed owing to its high cost and invasiveness. Read More

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Hypopharyngeal-Esophageal Impedance-pH Monitoring Profiles of Laryngopharyngeal Reflux Patients.

Laryngoscope 2021 02 21;131(2):268-276. Epub 2020 May 21.

Laryngopharyngeal Reflux Study Group of Young Otolaryngologists of the International Federation of Otorhinolaryngological Societies, Paris, France.

Objectives/hypothesis: To investigate the profile of patients with laryngopharyngeal reflux (LPR) at hypopharyngeal-esophageal multichannel intraluminal impedance-pH (HEMII-pH) monitoring and the relationship between hypopharyngeal-proximal reflux episodes (HREs) and saliva pepsin concentration.

Study Design: Prospective non-controlled.

Methods: Patients were recruited from three European hospitals from January 2018 to October 2019. Read More

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February 2021

Laryngeal Mucosa Alterations in Mice Model of Gastroesophageal Reflux: Effects of Topical Protection.

Laryngoscope 2020 12 11;130(12):E889-E895. Epub 2020 Mar 11.

Laboratory of Physiopharmacology Study of Gastrointestinal Tract, Federal University of Ceará, Fortaleza, Brazil.

Objectives/hypothesis: The objectives of this study were to evaluate laryngeal inflammation and mucosal integrity in a murine model of reflux disease and to assess the protective effects of topical agents including alginate, hyaluronic acid, and cashew gum.

Study Design: Animal study.

Methods: A surgical murine model of reflux disease was evaluated at 3 or 7 days postsurgery, and laryngeal samples were collected to measure inflammation (wet weight and myeloperoxidase [MPO]) and mucosal integrity (transepithelial resistance [TER] and mucosal permeability to fluorescein). Read More

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December 2020

Validation of the Brazilian Portuguese Version of the Reflux Finding Score.

J Voice 2020 Feb 10. Epub 2020 Feb 10.

Attending Physician Otolaryngology Division, Fleury Medicina e Saúde Diagnostic Laboratories, São Paulo, SP, Brazil.

Introduction: Laryngopharyngeal reflux (LPR) poses a diagnostic challenge. Clinical diagnosis, based on suggestive symptoms and laryngoscopic signs of inflammation, should be acceptable, as long as diligent differential diagnosis is sought. In order to minimize subjectivity, a number of diagnostic instruments have been proposed, being the most common the Reflux Symptom Index and the Reflux Finding Score (RFS). Read More

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February 2020