553 results match your criteria Reflux Laryngitis


Validity and reliability of the reflux symptom score.

Laryngoscope 2019 Apr 14. Epub 2019 Apr 14.

Research Committee of the Young Otolaryngologists of the International Federation of Oto-Rhino-Laryngological Societies (YO-IFOS), Marseille, France.

Objectives/hypothesis: To develop and validate the Reflux Symptom Score (RSS), a self-administered patient-reported outcome questionnaire for patients with laryngopharyngeal reflux (LPR).

Study Design: Prospective controlled study.

Methods: A total of 113 patients with LPR were enrolled and treated with diet and 3 months of pantoprazole, alginate, and/or magaldrate depending on the LPR characteristics (acid, nonacid, or mixed). Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1002/lary.28017
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http://dx.doi.org/10.1002/lary.28017DOI Listing
April 2019
3 Reads

Perceptual, Aerodynamic, and Acoustic Characteristics of Voice Changes in Patients with Laryngopharyngeal Reflux Disease.

Ear Nose Throat J 2019 Apr 8:145561319840830. Epub 2019 Apr 8.

1 Laboratory of Anatomy and Cell Biology, Faculty of Medicine, UMONS Research Institute for Health Sciences and Technology, University of Mons (UMons), Mons, Belgium.

Laryngopharyngeal reflux (LPR) is an inflammatory condition suspected to be associated with dysphonia. In this study, we investigated multidimensional perceptual, aerodynamic, and acoustic voice changes in patients with clinically diagnosed LPR compared to healthy participants. We prospectively included 80 outpatients with Reflux Finding Score (RFS) >7 and Reflux Symptom Index (RSI) >13 from September 2013 to April 2016 and we compared clinical and voice quality assessments of these patients with 80 healthy participants. Read More

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http://dx.doi.org/10.1177/0145561319840830DOI Listing

[Acute and chronic laryngitis in the subjects engaged in the voice and speech professions].

Vestn Otorinolaringol 2019 ;84(1):68-71

Saint-Petersburg Research Institute of Ear, Throat, Nose and Speech, Ministry of Health of the Russian Federation, Saint-Petersburg, Russia, 190013.

Laryngitis is one of the commonest causes of dysphonia in the subjects engaged in the voice and speech professions. This condition can be either associated with the professional activities or related to voice fatigue. It is a common practice to distinguish between acute and chronic forms of occupational laryngitis. Read More

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http://dx.doi.org/10.17116/otorino20198401168DOI Listing
January 2019
8 Reads

Risk factors associated with oral manifestations and oral health impact of gastro-oesophageal reflux disease: a multicentre, cross-sectional study in Pakistan.

BMJ Open 2019 Mar 30;9(3):e021458. Epub 2019 Mar 30.

Department of Prosthodontics and Implantology, King Faisal University, Al-Hasa, Saudi Arabia.

Objective: Gastro-oesophageal reflux disease (GORD) is a relatively common disorder and manifests with extraoesophageal symptoms, such as dental erosions (DE), cough, laryngitis, asthma, and oral soft- and hard-tissue pathologies. This study aimed (1) to identify oral soft and hard-tissue changes in patients with GORD and (2) to evaluate these oral changes as indices for assessing GORD and its severity.

Setting: This cross-sectional study was conducted at four major tertiary care government hospitals, in two metropolitan cities of Pakistan. Read More

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http://bmjopen.bmj.com/lookup/doi/10.1136/bmjopen-2017-02145
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http://dx.doi.org/10.1136/bmjopen-2017-021458DOI Listing
March 2019
6 Reads
2.063 Impact Factor

Evaluation and Management of Laryngopharyngeal Reflux Disease: State of the Art Review.

Otolaryngol Head Neck Surg 2019 Feb 12:194599819827488. Epub 2019 Feb 12.

14 Division of Gastroenterology, Hepatology, Nutrition, Vanderbilt University Medical Center, Nashville, Tennessee, USA.

Objective: To review the current literature about the epidemiology, clinical presentation, diagnosis, and treatment of laryngopharyngeal reflux (LPR).

Data Sources: PubMed, Cochrane Library, and Scopus.

Methods: A comprehensive review of the literature on LPR epidemiology, clinical presentation, diagnosis, and treatment was conducted. Read More

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http://dx.doi.org/10.1177/0194599819827488DOI Listing
February 2019
8 Reads

[Application of reflux symptom index in diagnosis of allergic patients with laryngopharyngeal reflux].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Nov;32(22):1711-1713

Department of Otolaryngology, the Affiliated Hospital of Chengde Medical University, Chengde, 067000, China.

To explore the diagnostic value and optimal diagnostic threshold of reflux symptom index(RSI) in allergic patients with laryngopharyngeal reflux. All the adult allergic patients with respiratory tract symptoms completed the RSI with the consent of the patients. A total of 150 patients with RSI>13 were screened out. Read More

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http://www.cnki.net/kcms/doi/10.13201/j.issn.1001-1781.2018.
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http://dx.doi.org/10.13201/j.issn.1001-1781.2018.22.007DOI Listing
November 2018
10 Reads

Clinical outcomes of laryngopharyngeal reflux treatment: A systematic review and meta-analysis.

Laryngoscope 2019 May 30;129(5):1174-1187. Epub 2018 Dec 30.

Division of Gastroenterology, Hepatology, Nutrition, Vanderbilt University Medical Center, Nashville, Tennessee, U.S.A.

Objectives: To investigate the therapeutic benefit of proton pump inhibitors (PPIs) over placebo in patients with laryngopharyngeal reflux (LPR) and to analyze the epidemiological factors of heterogeneity in the literature.

Methods: An electronic literature search was conducted to identify articles published between 1990 and 2018 about clinical trials describing the efficiency of medical treatment(s) on LPR. First, a meta-analysis of placebo randomized controlled trials (RCTs) comparing PPIs versus placebo was conducted according to diet. Read More

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http://dx.doi.org/10.1002/lary.27591DOI Listing
May 2019
1 Read

Establishment of a novel and effective reflux laryngitis model in rabbits: a preliminary study.

Eur Arch Otorhinolaryngol 2019 Jan 10;276(1):175-183. Epub 2018 Dec 10.

The Department of Otolaryngology-Head and Neck Surgery, Eye, Ear, Nose, and Throat Hospital of Fudan University, 83 Fenyang Road, Shanghai, 200030, China.

Purpose: To establish a novel and effective reflux model with a modified nasogastric aspiration tube and to investigate the association between different types of nasogastric aspiration tubes and reflux laryngitis, we conducted this study.

Methods: Thirty-eight healthy New Zealand albino rabbits (2.5-3. Read More

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http://link.springer.com/10.1007/s00405-018-5234-7
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http://dx.doi.org/10.1007/s00405-018-5234-7DOI Listing
January 2019
18 Reads

Laryngopharyngeal reflux and benign lesions of the vocal folds.

Eur Arch Otorhinolaryngol 2019 Jan 21;276(1):277-278. Epub 2018 Nov 21.

Department of Anatomy and Experimental Oncology, Mons School of Medicine, UMONS Research Institute for Health Sciences and Technology, University of Mons (UMons), Mons, Belgium.

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http://dx.doi.org/10.1007/s00405-018-5217-8DOI Listing
January 2019
23 Reads

[Vocal Changes and Laryngeal Modifications in the Elderly (Presbyphonia and Presbylarynx)].

Laryngorhinootologie 2018 Nov 7;97(11):772-776. Epub 2018 Nov 7.

In about 20 % of the population older than 60 years of age, voice problems (presbyphonia) are manifest, often combined with hearing deficits (presbyacusis), swallowing disorders (presbyphagia), dizziness (presbyvertigo) and/or impaired vision (presbyopia).The singing voice is afflicted more often, earlier and more severely than the speaking voice. But it is not just the vocal quality and capacity that are affected. Read More

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http://dx.doi.org/10.1055/a-0652-6758DOI Listing
November 2018
12 Reads

ARE THE PERSISTENT SYMPTOMS TO PROTON PUMP INHIBITOR THERAPY DUE TO REFRACTORY GASTROESOPHAGEAL REFLUX DISEASE OR TO OTHER DISORDERS?

Arq Gastroenterol 2018 Nov 4;55Suppl 1(Suppl 1):85-91. Epub 2018 Oct 4.

Universidade de São Paulo, Faculdade de Medicina, Hospital das Clínicas, Departamento de Gastroenterologia, São Paulo, SP, Brasil.

Background: Gastroesophageal reflux disease (GERD) is a clinical condition that develops when the reflux of stomach contents causes troublesome symptoms and/or complications. Transient lower esophageal sphincter relaxation is the main pathophysiological mechanism of GERD. Symptoms and complications can be related to the reflux of gastric contents into the esophagus, oral cavity, larynx and/or the lung. Read More

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http://dx.doi.org/10.1590/S0004-2803.201800000-48DOI Listing
November 2018
4 Reads

Voice Quality as Therapeutic Outcome in Laryngopharyngeal Reflux Disease: A Prospective Cohort Study.

J Voice 2018 Sep 13. Epub 2018 Sep 13.

Laboratory of Anatomy and Cell Biology, Faculty of Medicine, UMONS Research Institute for Health Sciences and Technology, University of Mons (UMons), Mons, Belgium; Department of Otorhinolaryngology and Head and Neck Surgery, RHMS Baudour, EpiCURA Hospital, Baudour, Belgium; Department of Otorhinolaryngology and Head and Neck Surgery, Faculté de medicine, CHU Saint-Pierre, Université Libre de Bruxelles, Bruxelles, Belgium.

Purpose: To study the usefulness of voice quality as therapeutic outcome in laryngopharyngeal reflux disease.

Material And Methods: A total of 80 patients with reflux finding score (RFS) > 7 and reflux symptom index (RSI) > 13 were treated with pantoprazole, diet, and lifestyle recommendations for 3 months. The therapeutic effectiveness was assessed with RSI; RFS; Voice Handicap Index; blinded Grade, Roughness, Breathiness, Asthenia, Strain, and Instability (GRBASI); aerodynamic and a panel of acoustic measurements before and after treatment. Read More

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http://dx.doi.org/10.1016/j.jvoice.2018.08.018DOI Listing
September 2018
7 Reads

The development of new clinical instruments in laryngopharyngeal reflux disease: The international project of young otolaryngologists of the International Federation of Oto-rhino-laryngological Societies.

Eur Ann Otorhinolaryngol Head Neck Dis 2018 Sep 28;135(5S):S85-S91. Epub 2018 Aug 28.

Laryngopharyngeal Reflux Study Group of Young Otolaryngologists of International Federation of Oto-rhino-laryngological Societies, Belgium; Department of Anatomy and Experimental Oncology, Mons School of Medicine, UMONS Research Institute for Health Sciences and Technology, University of Mons (UMons), Mons, Belgium; Department of Otorhinolaryngology and Head and Neck Surgery, CHU Saint-Pierre, Université Libre de Bruxelles, School of Medicine, Brussels, Belgium.

Introduction: To analyze the epidemiological characteristics of placebo controlled randomized trials (RCTs) that evaluated the effectiveness of medical treatments over placebo in laryngopharyngeal reflux (LPR).

Material And Methods: PubMed, Cochrane database, and Scopus were assessed for subject headings using the PRISMA recommendations. Placebo RCTs published between 1990 and 2018 describing clinical evolution throughout LPR treatment were extracted and analyzed for evidence-based level, number of patients, inclusion and exclusion criteria, gender, age, symptoms and signs used as therapeutic outcomes, and treatment schemes. Read More

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http://dx.doi.org/10.1016/j.anorl.2018.05.013DOI Listing
September 2018
7 Reads

Characteristics and Voice Outcomes of Ulcerative Laryngitis.

J Voice 2018 Aug 28. Epub 2018 Aug 28.

University of California-San Francisco, Department of Otolaryngology-Head and Neck Surgery, San Francisco, California.

Objectives: Ulcerative laryngitis (UL) is challenging in terms of treatment and patient counseling, with few reports in the literature. This study describes UL patients and their clinical course including detailed voice and stroboscopic outcomes after treatment which have not been described in previous literature.

Methods: Single-institution, retrospective review of 23 UL patients. Read More

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http://dx.doi.org/10.1016/j.jvoice.2018.07.021DOI Listing
August 2018
23 Reads

Laryngopharyngeal reflux disease in singers: Pathophysiology, clinical findings and perspectives of a new patient-reported outcome instrument.

Eur Ann Otorhinolaryngol Head Neck Dis 2018 Aug 27. Epub 2018 Aug 27.

Laboratory of Phonetics, Faculty of Psychology, Research Institute for Language Sciences and Technology, University of Mons (UMons), Mons, Belgium; Laryngopharyngeal Reflux Study Group of Young Otolaryngologists of International Federation of Oto-rhino-laryngological Societies, Paris, France; Department of Otorhinolaryngology and Head and Neck Surgery, CHU de Liège, Faculty of Medicine, University of Liège, Liège, Belgium.

Purpose Of Review: Laryngopharyngeal reflux (LPR) is an inflammatory disease associated with the development of voice disorder and vocal fold lesions. The occurrence of LPR in professional voice users as singers can have a dramatic impact of daily life. The aims of this paper is to review the current literature about the pathophysiological mechanisms underlying the development of voice disorder, especially in singers, and to propose a new patient-reported outcome instrument to assess complaints of these patients. Read More

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http://dx.doi.org/10.1016/j.anorl.2018.08.008DOI Listing
August 2018
7 Reads

Safety and utility of direct laryngoscopy and bronchoscopy in patients hospitalized with croup.

Ear Nose Throat J 2018 Aug;97(8):E25-E30

Texas ENT Specialists, 23920 Katy Fwy., Suite 430, Katy, TX 77494, USA.

Acute croup is a common admitting diagnosis for pediatric patients. If a patient is not responding to medical management for presumed croup, the otolaryngology team is occasionally consulted for direct laryngoscopy and bronchoscopy (DLB) to rule out tracheitis or another airway pathology. We conducted a study to determine if inpatient DLB in acute croup is safe and efficacious and to correlate preoperative vital signs with intraoperative findings. Read More

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http://dx.doi.org/10.1177/014556131809700805DOI Listing
August 2018
1 Read

Gaviscon® Advance alone versus co-prescription of Gaviscon® Advance and proton pump inhibitors in the treatment of laryngopharyngeal reflux.

Eur Arch Otorhinolaryngol 2018 Oct 30;275(10):2515-2521. Epub 2018 Jul 30.

Department of Otorhinolaryngology - Head and Neck Surgery, Warrington and Halton Hospitals NHS Foundation Trust, Lovely Lane, Warrington, WA5 1QG, UK.

Objectives: Management of laryngopharyngeal reflux (LPR) typically comprises alginates and proton pump inhibitors (PPIs) alone or in combination, yet evidence to support any particular treatment regimen is lacking. We sought to evaluate the efficacy of Gaviscon® Advance alone versus co-prescription with a PPI in treating LPR.

Methods: One hundred consecutive LPR patients with a reflux symptom index (RSI) score > 10 attending our joint voice clinic (JVC) were studied prospectively. Read More

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http://dx.doi.org/10.1007/s00405-018-5079-0DOI Listing
October 2018
25 Reads

Impact of Laryngopharyngeal Reflux on Subjective, Aerodynamic, and Acoustic Voice Assessments of Responder and Nonresponder Patients.

J Voice 2018 Jul 26. Epub 2018 Jul 26.

Laboratory of Anatomy and Cell Biology, Faculty of Medicine, UMONS Research Institute for Health Sciences and Technology, University of Mons (UMons), Mons, Belgium; Department of Otorhinolaryngology and Head and Neck Surgery, RHMS Baudour, EpiCURA Hospital, Baudour, Belgium.

Objective: To investigate the usefulness of voice quality assessment as a treatment outcome in responder and nonresponder patients with laryngopharyngeal reflux (LPR).

Material And Methods: Eighty clinically diagnosed LPR patients with reflux finding score (RFS) > 7 and reflux symptom index (RSI) > 13 were treated with pantoprazole, lifestyle changes, and diet recommendations for three months. RSI; RFS; Voice Handicap Index; blinded Grade, Roughness, Breathiness, Asthenia, Strain, and Instability; aerodynamic and acoustic measurements were assessed at baseline and after treatment. Read More

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http://dx.doi.org/10.1016/j.jvoice.2018.05.014DOI Listing
July 2018
9 Reads

Evaluation of gastroesophageal reflux disease.

Updates Surg 2018 Sep 23;70(3):309-313. Epub 2018 Jul 23.

Department of Medicine and Surgery, University of North Carolina School of Medicine, Chapel Hill, NC, USA.

Patients with gastroesophageal reflux disease (GERD) may present with a variety of symptoms, including heartburn, regurgitation, dysphagia, chronic cough, laryngitis, or even asthma. Therefore, the clinical presentation of GERD varies among individuals and conversely symptoms not always correspond to the presence of actual reflux. For that reason, the diagnosis poses certain challenges to the physician. Read More

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http://dx.doi.org/10.1007/s13304-018-0563-zDOI Listing
September 2018
13 Reads

Eosinophilic granulomatosis with polyangiitis and laryngeal involvement: review of the literature and a cross-sectional prospective experience.

J Laryngol Otol 2018 Jul 11;132(7):619-623. Epub 2018 Jun 11.

Rheumatology Unit,University of Pisa,Italy.

Background: Eosinophilic granulomatosis with polyangiitis and granulomatosis with polyangiitis show variable otorhinolaryngological involvement. Up to 14 per cent of granulomatosis with polyangiitis patients have subglottis involvement; little is known about the laryngeal involvement in eosinophilic granulomatosis with polyangiitis.

Method: A literature review was conducted, together with a prospective cross-sectional analysis of 43 eosinophilic granulomatosis with polyangiitis patients. Read More

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http://dx.doi.org/10.1017/S0022215118000737DOI Listing
July 2018
2 Reads

Medical Therapy of Gastroesophageal Reflux Disease Beyond Proton Pump Inhibitors: Where Are We Heading?

Authors:
Herbert Koop

Visc Med 2018 Apr 29;34(2):110-115. Epub 2018 Mar 29.

formerly Department of General Internal Medicine and Gastroenterology, Helios Klinikum Berlin-Buch, Berlin, Germany.

Proton pump inhibitors (PPI) have greatly improved the treatment of gastroesophageal reflux disease. However, recent investigations have revealed that reflux symptoms persist in a substantial number of patients. Therefore, treatment strategies beyond PPI are urgently required. Read More

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http://dx.doi.org/10.1159/000486692DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5981673PMC
April 2018
3 Reads

Change of signs, symptoms and voice quality evaluations throughout a 3- to 6-month empirical treatment for laryngopharyngeal reflux disease.

Clin Otolaryngol 2018 10 5;43(5):1273-1282. Epub 2018 Jun 5.

Faculty of Medicine, Laboratory of Anatomy and Cell Biology, UMONS Research Institute for Health Sciences and Technology, University of Mons (UMons), Mons, Belgium.

Objective: To assess the usefulness of voice quality measurements as a treatment outcome in patients with laryngopharyngeal reflux (LPR)-related symptoms.

Design: Prospective uncontrolled multi-centre study.

Material And Methods: A total of 80 clinically diagnosed LPR patients with a reflux finding score (RFS)>7 and a reflux symptom index (RSI)>13 were treated with pantoprazole and diet recommendations during 3 or 6 months, according to their evolution. Read More

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http://dx.doi.org/10.1111/coa.13140DOI Listing
October 2018

Correlation between Allergic Rhinitis and Laryngopharyngeal Reflux.

Biomed Res Int 2018 22;2018:2951928. Epub 2018 Mar 22.

Department of Otolaryngology, Head & Neck Surgery, Prince Sultan Medical Military City, Riyadh, Saudi Arabia.

Background And Objectives: Laryngopharyngeal reflux (LPR) exhibits nonspecific clinical presentations, and these symptoms may be associated with other conditions such as allergies, including allergic rhinitis and laryngitis. However, there is a gap in the literature regarding the correlation of laryngopharyngeal reflux with allergic rhinitis/laryngitis. Hence, the aim of this study is to explore the correlation between these two conditions. Read More

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http://dx.doi.org/10.1155/2018/2951928DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5885348PMC
October 2018
1 Read

The Effects of Reflux on the Elderly: The Problems with Medications and Interventions.

Otolaryngol Clin North Am 2018 Aug 24;51(4):779-787. Epub 2018 Apr 24.

Department of Head and Neck Surgery, UCLA Voice Center for Medicine and the Arts, 200 Medical Plaza, Suite 550, Los Angeles, CA 90095, USA. Electronic address:

Reflux-related complaints are a frequent cause for otolaryngology consultation, and with the aging population the concerns specific to the elderly reflux patient are critical. The elderly patient is less likely to present with typical laryngopharyngeal reflux (LPR) or gastroesophageal reflux disease (GERD) symptoms. Importantly, elderly patients typically have objective findings more severe than the level of the symptoms. Read More

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http://dx.doi.org/10.1016/j.otc.2018.03.007DOI Listing
August 2018
5 Reads

[Laryngopharyngeal Reflux].

Laryngorhinootologie 2018 04 10;97(4):238-245. Epub 2018 Apr 10.

Technische Universität München Hals-Nasen-Ohrenklinik.

The prevalence of laryngopharyngeal reflux (LPR) is around 31 % in the general population. Patients with a dysphonia or other laryngeal diseases are accompanied up to 50 % by an LPR. Typical reflux associated diseases of the larynx are a chronical laryngitis and a contact granuloma. Read More

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http://dx.doi.org/10.1055/s-0044-100794DOI Listing
April 2018
3 Reads

Gender differences in the presentation of dysphonia related to laryngopharyngeal reflux disease: a case-control study.

Eur Arch Otorhinolaryngol 2018 Jun 26;275(6):1513-1524. Epub 2018 Mar 26.

Laboratory of Anatomy and Cell Biology, Faculty of Medicine, UMONS Research Institute for Health Sciences and Technology, University of Mons (UMons), Avenue du Champ de mars, 6, 7000, Mons, Belgium.

Objective: To investigate the voice quality impairments in patients with laryngopharyngeal reflux (LPR) according to the gender.

Design: Controlled multi-center study.

Materials And Methods: 80 LPR patients (40 males and 40 females) with reflux finding score (RFS) > 7 and reflux symptom index (RSI) > 13 were included and clinically compared according to gender. Read More

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http://dx.doi.org/10.1007/s00405-018-4951-2DOI Listing
June 2018
6 Reads

SWALLOWING IN PATIENTS WITH LARYNGITIS.

Arq Gastroenterol 2018 Jan-Mar;55(1):50-54

Departamento de Oftalmologia, Otorrinolaringologia, Cirurgia de Cabeça e Pescoço e Departamento de Clínica Médica, Faculdade de Medicina de Ribeirão Preto - Universidade de São Paulo, Ribeirão Preto, SP, Brasil.

Background: Dysphagia is described as a complaint in 32% of patients with laryngitis.

Objective: The objective of this investigation was to evaluate oral and pharyngeal transit of patients with laryngitis, with the hypothesis that alteration in oral-pharyngeal bolus transit may be involved with dysphagia.

Methods: Videofluoroscopic evaluation of the swallowing of liquid, paste and solid boluses was performed in 21 patients with laryngitis, 10 of them with dysphagia, and 21 normal volunteers of the same age and sex. Read More

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http://dx.doi.org/10.1590/S0004-2803.201800000-10DOI Listing
April 2018
5 Reads

Clinical Practice Guideline: Hoarseness (Dysphonia) (Update).

Otolaryngol Head Neck Surg 2018 Mar;158(1_suppl):S1-S42

15 Department of Research and Quality, American Academy of Otolaryngology-Head and Neck Surgery Foundation, Alexandria, Virginia, USA.

Objective This guideline provides evidence-based recommendations on treating patients who present with dysphonia, which is characterized by altered vocal quality, pitch, loudness, or vocal effort that impairs communication and/or quality of life. Dysphonia affects nearly one-third of the population at some point in its life. This guideline applies to all age groups evaluated in a setting where dysphonia would be identified or managed. Read More

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http://dx.doi.org/10.1177/0194599817751030DOI Listing
March 2018
13 Reads

Clinical Practice Guideline: Hoarseness (Dysphonia) (Update) Executive Summary.

Otolaryngol Head Neck Surg 2018 Mar;158(3):409-426

15 Department of Research and Quality, American Academy of Otolaryngology-Head and Neck Surgery Foundation, Alexandria, Virginia, USA.

Objective This guideline provides evidence-based recommendations on treating patients presenting with dysphonia, which is characterized by altered vocal quality, pitch, loudness, or vocal effort that impairs communication and/or quality of life. Dysphonia affects nearly one-third of the population at some point in its life. This guideline applies to all age groups evaluated in a setting where dysphonia would be identified or managed. Read More

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http://dx.doi.org/10.1177/0194599817751031DOI Listing
March 2018
23 Reads

Extraesophageal Symptoms and Diseases Attributed to GERD: Where is the Pendulum Swinging Now?

Clin Gastroenterol Hepatol 2018 Jul 7;16(7):1018-1029. Epub 2018 Feb 7.

CHU Bordeaux, Department of Gastroenterology, Hepatology and Digestive Oncology, University of Bordeaux, Bordeaux, France.

The purpose of this review is to outline the recent developments in the field of extraesophageal reflux disease and provide clinically relevant recommendations. The recommendations outlined in this review are based on expert opinion and on relevant publications from PubMed and EMbase. The Clinical Practice Updates Committee of the American Gastroenterological Association proposes the following recommendations: Best Practice Advice 1: The role of a gastroenterologist in patients referred for evaluation of suspected extra esophageal symptom is to assess for gastroesophageal etiologies that could contribute to the presenting symptoms. Read More

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http://dx.doi.org/10.1016/j.cgh.2018.02.001DOI Listing
July 2018
4 Reads

Characteristics of a Treatment-seeking Population in a Private Practice Community Voice Clinic: An Epidemiologic Study.

J Voice 2018 Jan 5. Epub 2018 Jan 5.

a tempo Voice Center, Fort Worth, Texas.

Objective: The purpose of this study was to evaluate epidemiologic characteristics of a treatment-seeking population referred to a private practice community voice clinic.

Study Design: This is a retrospective cohort study.

Methods: Patient files representing evaluation referrals over a 28-month period were reviewed. Read More

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http://dx.doi.org/10.1016/j.jvoice.2017.11.019DOI Listing
January 2018
3 Reads

There is no correlation between signs of reflux laryngitis and reflux oesophagitis in patients with gastro-oesophageal reflux disease symptoms.

Acta Otorhinolaryngol Ital 2017 Oct;37(5):401-405

Department of Otolaryngology, University Hospital Ostrava, Ostrava, Czech Republic.

The objective of the present study was to determine if there is correlation between signs of reflux laryngitis (RL) and reflux oesophagitis (RE) in patients with gastro-oesophageal reflux disease (GORD) symptoms. Laryngeal photography obtained from patients during oesophagogastroduodenoscopy were examined by two otolaryngologists experienced in the field of extra-oesophageal reflux regarding the presence and severity of RL. The presence of RE was evaluated by gastroenterologist. Read More

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http://dx.doi.org/10.14639/0392-100X-1237DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5720868PMC
October 2017
2 Reads

MRSA chronic bacterial laryngitis: A growing problem.

Laryngoscope 2018 04 31;128(4):921-925. Epub 2017 Oct 31.

Department of Surgery Division of Otolaryngology-Head and Neck Surgery, University of Utah Health System, Salt Lake City, Utah, U.S.A.

Objectives: Chronic bacterial infection of the larynx is characterized by long-standing hoarseness and exudative laryngitis. Prolonged antibiotic therapy is required to clear the infection, and methicillin-resistant staphylococcus aureus (MRSA) may be the responsible pathogen. The objective of this study was to describe the presentation, comorbidities, treatment response, and underlying etiology- including the incidence of MRSA-in our patient population with chronic bacterial laryngitis. Read More

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http://dx.doi.org/10.1002/lary.26955DOI Listing
April 2018
2 Reads

[The prevalence of the fungal flora in association with chronic inflammatory pathology of the larynx].

Vestn Otorinolaringol 2017;82(4):29-31

L.I. Sverzhevskiy Research Institute of Clinical Otorhinolaryngology, Moscow Health Department, Moscow, Russia, 117152.

The present article was designed to analyze the prevalence and clinical features of laryngomycosis associated with chronic inflammatory diseases of the larynx. We examined 430 patients suffering from chronic pharyngitis and found the fungal flora in 100 (23.2%) of them. Read More

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http://dx.doi.org/10.17116/otorino201782429-31DOI Listing
November 2017
4 Reads

Respiratory manifestations of gastro-oesophageal reflux in children.

Arch Dis Child 2018 03 7;103(3):292-296. Epub 2017 Sep 7.

Department of Paediatric Respiratory Medicine, Royal Brompton Hospital, London, UK.

Gastro-oesophageal reflux disease (GORD) is a complex problem in children. Suspected respiratory manifestations of GORD, such as asthma, chronic cough and laryngitis, are commonly encountered in the paediatric practice, but continue to be entities with more questions than answers. The accuracy of diagnostic tests (ie, pH or pH-impedance monitoring, laryngoscopy, endoscopy) for patients with suspected extraoesophageal manifestations of GORD is suboptimal and therefore whether there is a causal relationship between these conditions remains largely undetermined. Read More

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http://dx.doi.org/10.1136/archdischild-2017-312890DOI Listing
March 2018
10 Reads

Facts and Fantasies on Extraesophageal Reflux: A Gastroenterologist Perspective.

J Clin Gastroenterol 2017 Oct;51(9):769-776

Univ. Bordeaux, CHU Bordeaux, Gastroenterology, Hepatology and Digestive Oncology Department, Magellan Medical and Surgical Center, Haut Lévêque Hospital, Bordeaux, France.

Gastroesophageal reflux disease encompasses a wide spectrum of disorders related to the reflux of gastric contents into the esophagus. Extraesophageal reflux (EER) may be suspected in patients with unexplained chronic cough, pharyngolaryngeal symptoms, and asthma. For physicians, suspected EER is challenging as there is currently no tool that can reliably make a definitive diagnosis. Read More

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http://dx.doi.org/10.1097/MCG.0000000000000918DOI Listing
October 2017
3 Reads

Randomized double blind trial of amitriptyline versus placebo in treatment of chronic laryngopharyngeal neuropathy.

Am J Otolaryngol 2017 Nov - Dec;38(6):683-687. Epub 2017 Jul 12.

Department of Otolaryngology, Boston Medical Center, Boston University, Boston, MA 02118, United States. Electronic address:

Objective: A neuropathic etiology has been suggested for patients with chronic laryngopharyngitis symptoms without visible structural pathology. Prior studies have shown that treatment with neuro-modulating medications is beneficial, but it is unknown if this was due to placebo effect. Our objective was to compare the efficacy of amitriptyline versus placebo in treating chronic laryngopharyngeal neuropathy. Read More

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http://dx.doi.org/10.1016/j.amjoto.2017.07.006DOI Listing
July 2018
34 Reads

An innovative mindfulness and educational care approach in an adult patient affected by gastroesophageal reflux: the IARA model.

J Complement Integr Med 2017 May 16;14(4). Epub 2017 May 16.

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Patients affected by gastroesophageal reflux disease (GERD) have a poor quality of life caused by several manifestations such as cough, asthma, laryngitis and dental erosion. The clinical conditions are highly disabling for patients and symptoms are difficult to manage. These conditions lead to many discomforts which contribute to an increase of the disease perception. Read More

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http://dx.doi.org/10.1515/jcim-2016-0154DOI Listing
May 2017
7 Reads

Impact of age on laryngopharyngeal reflux disease presentation: a multi-center prospective study.

Eur Arch Otorhinolaryngol 2017 Oct 17;274(10):3687-3696. Epub 2017 Jul 17.

Laboratory of Anatomy and Cell Biology, Faculty of Medicine, UMONS Research Institute for Health Sciences and Technology, University of Mons (UMons), Avenue du Champ de mars, 6, B7000, Mons, Belgium.

The objective is to assess the differences in the severity of symptoms, signs, voice quality, and quality of life before and after treatment according to age in suspected laryngopharyngeal reflux (LPR) patients. The design used in this paper is prospective multi-center study. Eighty clinically diagnosed LPR patients with a reflux finding score (RFS) >7 and a reflux symptom index (RSI) >13 were treated with pantoprazole and diet recommendations for 3 months. Read More

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http://dx.doi.org/10.1007/s00405-017-4671-zDOI Listing
October 2017
11 Reads

Substernal goiter and laryngopharyngeal reflux.

Arch Endocrinol Metab 2017 Jul-Aug;61(4):348-353. Epub 2017 Jun 26.

Disciplina de Cirurgia de Cabeça e Pescoço do Hospital das Clínicas da FMUSP, São Paulo, SP, Brasil.

Objective: This study aims to compare the prevalence of laryngopharyngeal reflux signs between two groups of patients undergoing thyroidectomy for voluminous goiter: substernal goiters and voluminous cervical goiter without thoracic extension.

Subjects And Methods: A retrospective case-control study was performed with data retrieved of the charts of the patients submitted to thyroidectomies occurred at a tertiary care center (Head and Neck Surgery Department, University of São Paulo Medical School) between 2010 and 2014. The selected thyroidectomies were allocated in two groups for study: patients with substernal goiters and patients with voluminous cervical goiter without thoracic extension. Read More

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http://dx.doi.org/10.1590/2359-3997000000266DOI Listing
October 2017
22 Reads

Salivary epidermal growth factor concentrations in patients with Sjögren syndrome and laryngopharyngeal reflux.

Ear Nose Throat J 2017 Jun;96(6):E6-E11

Department of Otolaryngology, Santa Casa School of Medicine and Hospitals, Av. Vereador José Diniz 3457, cj 501, São Paulo, Brazil.

Sjögren syndrome was chosen as a clinical model to study acinar salivary deficiencies in the development of laryngopharyngeal reflux (LPR). The objective of this prospective cohort study was to compare salivary epidermal growth factor (EGF) concentrations of patients with Sjögren syndrome with and without LPR and gastroesophageal reflux disease (GERD) with normal controls. LPR was diagnosed with positive scores on the Reflux Symptom Index and Reflux and Reflux Finding Score, corroborated by esophagogastroduodenoscopy and/or 24-hour pH-metry. Read More

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http://dx.doi.org/10.1177/014556131709600602DOI Listing
June 2017
7 Reads

Laryngopharyngeal Reflux and Voice Disorders: A Multifactorial Model of Etiology and Pathophysiology.

J Voice 2017 Nov 21;31(6):733-752. Epub 2017 Apr 21.

Department of Surgery, Harvard Medical School, Center for Laryngeal Surgery and Voice Rehabilitation, Massachusetts General Hospital, Boston, Massachusetts.

Objective: The aim of this paper is to shed light on the pathogenesis and pathophysiological mechanisms underlying the development of hoarseness related to laryngopharyngeal reflux disease (LPRD).

Material And Methods: PubMed, Embase, and The Cochrane Library were searched for the terms reflux, laryngopharyngeal, laryngitis, voice, and hoarseness. Experimental and clinical studies providing substantial information about the occurrence of voice disorders, laryngeal histologic changes, or any pathophysiological processes related to LPRD were included by two independent investigators. Read More

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http://dx.doi.org/10.1016/j.jvoice.2017.03.015DOI Listing
November 2017
11 Reads

Relationship between functional endoscopy and impedance-pH measurement.

HNO 2017 Aug;65(Suppl 2):116-121

Refluxcenter Darmstadt, Darmstadt, Germany.

Classic gastroenterological diagnostic tools have proven to be insufficient in identifying the causal relationship between extra-esophageal symptoms and presumed pathological reflux activity. Some new methodological approaches, such as functional endoscopy (video panendoscopy, VPE), are considered to be helpful. However, there are currently no data objectively verifying the success of this method. Read More

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http://dx.doi.org/10.1007/s00106-016-0317-5DOI Listing
August 2017
2 Reads

Allergic laryngitis: unraveling the myths.

Curr Opin Otolaryngol Head Neck Surg 2017 Jun;25(3):242-246

aDownriver ENT PC bDepartment of Otolaryngology, Wayne State University, Detroit Medical Center, Detroit, MI.

Purpose Of Review: This article provides a thorough review of the literature highlighting the articles that have advanced our knowledge about the sensitivity of the larynx to allergens in the air or ones consumed. This area of inquiry requires continued interest and investigation. As the field of clinical laryngology changes, and more information is discovered about the possible causal association between allergy and vocal pathologies, practicing otolaryngologists, allergists, and other medical professionals may discover more comprehensive methods to evaluate and treat their allergic patients, particularly those who present with complaints of dysphonia, dysphagia, laryngopharyngeal reflux (LPR), and/or dyspnea. Read More

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http://dx.doi.org/10.1097/MOO.0000000000000354DOI Listing
June 2017
9 Reads

Extra-esophageal presentation of gastroesophageal reflux disease: new understanding in a new era.

Minerva Gastroenterol Dietol 2017 Sep 3;63(3):221-234. Epub 2017 Mar 3.

Division of Pharmacology, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.

Associations of gastroesophageal reflux disease (GERD) with extraesophageal manifestations, such as chronic cough, asthma, and laryngitis, are reported frequently, and there is a strong evidence of biological plausibility in support of this relationship. On the other hand, extraesophageal reflux disease (EERD) is usually multifactorial in nature with reflux being just one of the several potential contributing cofactors. Moreover, the accuracy of currently available diagnostic tests for EERD is suboptimal, and therefore the causal relationship between GERD and EERD remains far from being conclusively proven. Read More

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http://www.minervamedica.it/index2.php?show=R08Y2017N03A0221
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http://dx.doi.org/10.23736/S1121-421X.17.02393-5DOI Listing
September 2017
18 Reads

Evaluation of Gastroesophageal Reflux Disease.

World J Surg 2017 07;41(7):1672-1677

Department of Surgery, St. Elizabeth Medical Center, Brighton, MA, USA.

Introduction: Gastroesophageal reflux disease (GERD) may present with heartburn, regurgitation, dysphagia, chronic cough, laryngitis, or even asthma. The clinical presentation of GERD is therefore varied and poses certain challenges to the physician, especially given the limitations of the diagnostic testing.

Discussion: The evaluation of patients with suspected GERD might be challenging. Read More

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http://dx.doi.org/10.1007/s00268-017-3953-3DOI Listing
July 2017
2 Reads

[Relationship between functional endoscopy and impedance-pH measurement. German version].

HNO 2017 Aug;65(8):657-662

Refluxzentrum Darmstadt, Darmstadt, Deutschland.

Classic gastroenterological diagnostic tools are proving increasingly insufficient for analyzing the complex causal relationship between extra-esophageal symptoms and presumed pathological reflux activity. Some new methodological approaches, such as functional endoscopy (videopanendoscopy, VPE), are considered to be helpful. However, there are currently no data objectively verifying the usefulness of this method. Read More

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http://link.springer.com/10.1007/s00106-016-0313-9
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http://dx.doi.org/10.1007/s00106-016-0313-9DOI Listing
August 2017
2 Reads

Impact of laryngopharyngeal reflux on subjective and objective voice assessments: a prospective study.

J Otolaryngol Head Neck Surg 2016 Nov 8;45(1):59. Epub 2016 Nov 8.

Laboratory of Anatomy and Cell Biology, Faculty of Medicine, UMONS Research Institute for Health Sciences and Technology, University of Mons (UMons), Avenue du Champ de mars, 6, B7000, Mons, Belgium.

Background: Laryngopharyngeal reflux is a prevalent, not well-understood disease affecting a high proportion of patients who seek laryngology consultation. The objective of this prospective case series is to explore the subjective and objective voice modifications in Laryngopharyngeal reflux (LPR), especially the usefulness of acoustic parameters as treatment outcomes, and to better understand the pathophysiological mechanisms underlying the development of voice disorder.

Methods: Forty-one patients with a reflux finding score (RFS) > 7 and a reflux symptom index (RSI) > 13 were enrolled and treated with pantoprazole 20 mg twice daily for three months. Read More

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http://dx.doi.org/10.1186/s40463-016-0171-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5101798PMC
November 2016
12 Reads

The Role of Helicobacter pylori in Laryngopharyngeal Reflux.

Otolaryngol Head Neck Surg 2017 02 1;156(2):255-262. Epub 2016 Nov 1.

1 Department of Otolaryngology-Head and Neck Surgery, University of Ottawa, Ottawa, Canada.

Objective The primary objective was to determine the prevalence of Helicobacter pylori among patients with laryngopharyngeal reflux. The secondary objective was determining if H pylori eradication leads to greater symptom improvement in patients with laryngopharyngeal reflux as compared with standard proton pump inhibitor therapy alone. Data Sources EMBASE, Cumulative Index to Nursing and Allied Health Literature, MEDLINE, World Health Organization International Clinical Trials Registry Platform, European Union Clinical Trials Register, Cochrane Library databases of clinical trials, and ClinicalTrials. Read More

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http://dx.doi.org/10.1177/0194599816676052DOI Listing
February 2017
25 Reads

Anticholinergic medication use is associated with globus pharyngeus.

J Laryngol Otol 2016 Dec 27;130(12):1125-1129. Epub 2016 Oct 27.

Department of Otorhinolaryngology: Head and Neck Surgery,University of Pennsylvania,Philadelphia,USA.

Background: Globus pharyngeus has been linked to salivary hypofunction. We hypothesise that a considerable portion of the globus experienced by patients is due to a drying effect secondary to anticholinergic medication use; this study aimed to determine their association.

Methods: A cross-sectional study was conducted of 270 patients who presented to a laryngology practice over 6 months. Read More

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http://www.journals.cambridge.org/abstract_S002221511600918X
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http://dx.doi.org/10.1017/S002221511600918XDOI Listing
December 2016
5 Reads