Search Our Scientific Publications & Authors

J Stroke Cerebrovasc Dis 2019 Feb 27. Epub 2019 Feb 27.

Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing, P.R. China. Electronic address:

Background: Reflex sympathetic dystrophy (RSD) is the common complication among stroke and cerebral injury patients, which is lack of safe and effective treatment. Electroacupuncture (EA) may potentially be a reliably therapy, but the evidence is insufficiency.

Methods: Cochrane Library, MEDLINE, Embase, Chinese National Knowledge Infrastructure, Wan Fang Data, the Chinese Biology Medicine disc, etc. Read More

Front Neurosci 2019 5;13:19. Epub 2019 Feb 5.

Ashirvad Institute for Pain Management and Research, Mumbai, India.

Reg Anesth Pain Med 2019 Mar;44(3):376-387

Department of Pain Management, Cleveland Clinic, Cleveland, OH 44024, USA

This account of the condition now termed complex regional pain syndrome (CRPS) spans approximately 462 years since a description embodying similar clinical features was described by Ambroise Paré in 1557. While reviewing its historical origins, the text describes why it became necessary to change the taxonomies of two clinical syndromes with similar pathophysiologies to one which acknowledges this aspect but does not introduce any mechanistic overtones. Discussed at length is the role of the sympathetic component of the autonomic nervous system (ANS) and why its dysfunction has both directly and indirectly influenced our understanding of the inflammatory aspects of CRPS. Read More

Br J Pain 2019 Feb 13;13(1):35-42. Epub 2018 Jun 13.

SI 'Institute of Traumatology and Orthopedics of the Academy of Medical Sciences of Ukraine', Kyiv, Ukraine.

Introduction: Mirror therapy requires a minimum of equipment, is relatively simple to perform and effective for various pathological conditions. The effect of mirror therapy on body schema disturbances registered in complex regional pain syndrome type I (CRPS I) patients has not yet been determined.

Methods: The study is based on the analysis of the treatment results of 30 patients with CRPS I, developed as a result of the distal radius fractures, with help of mirror therapy together with exercise therapy and medications. Read More

Autoimmun Rev 2019 Mar 11;18(3):270-278. Epub 2019 Jan 11.

Division of Rheumatology, Allergy and Clinical Immunology, University of California at Davis School of Medicine, United States. Electronic address:

Complex regional pain syndrome (CRPS) has been considered to be an autoimmune disease and there have been clinical trials with intravenous immunoglobulin. Often the etiology of the so-called CRPS diagnosis cannot be discerned and there are no validated instruments that provide functional metrics. The term complex regional pain syndrome (CRPS), coined in 1994 to describe patients in whom the pain is out of proportion to the injury, was actually a diagnosis proposed during the American Civil War, but was originally known as causalgia. Read More

Disabil Rehabil 2019 Jan 7:1-10. Epub 2019 Jan 7.

a Department of Rehabilitation Sciences , The Hong Kong Polytechnic University , Hung Hom , Hong Kong.

Purpose: To identify the existing evidence evaluating the cost-effectiveness of physiotherapy treatments for people with neurological disorders.

Methods: Multiple databases were searched from database inception until July 2018. Studies estimating the cost-effectiveness as incremental cost-effectiveness ratios, cost per quality-adjusted life year, cost per disability-adjusted life year and cost per other measurable results were included. Read More

Medicine (Baltimore) 2018 Dec;97(50):e13272

Division of Pain Medicine, Department of Anesthesiology, Hospital for Special Surgery, Weill Cornell Medicine, New York, New York.

Rationale: Continuous epidural infusion of local anesthetic may be an alternative to sympathetic blocks in refractory cases of complex regional pain syndrome (CRPS). Spinal epidural abscess (SEA) is a well-known complication associated with this technique, especially in patients with immune deficiencies. We herewith report a cervical SEA associated with an epidural catheter in a woman with CRPS and selective IgG3 subclass deficiency. Read More

Neurotherapeutics 2019 Jan;16(1):9-25

Division of Plastic and Reconstructive Surgery, Washington University in St. Louis, St. Louis, MO, USA.

Pain is a frequent cause of physician visits. Many physicians find these patients challenging because they often have complicated histories, emotional comorbidities, confusing examinations, difficult problems to fix, and the possibility of factitious complaints for attention or narcotic pain medications. As a result, many patients are lumped into the category of chronic, centralized pain and relegated to pain management. Read More

Pain Med 2019 Mar;20(3):429-433

Department of Psychiatry, Oregon Health & Science University, Portland, Oregon.

J Hand Surg Asian Pac Vol 2018 Dec;23(4):554-561

* Department of Occupational Therapy, The University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.

Background: To investigate the role of psychological factors (anxiety and depression) and pain measured on a visual analogue scale (VAS) in the development of complex regional pain syndrome type I (CRPS I) following the distal radius fracture (DRF).

Methods: A consecutive sample of patients (N=60) with a distal radius fracture was measured for signs of CRPS by Budapest criteria weekly till 8 weeks and then another follow-up one year after injury to determine the incidence and predictors of developing CRPS I in a prospective cohort study and also to discover whether there is difference between pain, depression, and anxiety level in the patients with and without CRPS I. The most of the patients were treated by Pin stabilization. Read More

J Neurol Neurosurg Psychiatry 2018 Oct 24. Epub 2018 Oct 24.

Centre for Clinical Brain Sciences, Western General Hospital, NHS Lothian and University of Edinburgh, Edinburgh, UK

There have been many articles highlighting differences and similarities between complex regional pain syndrome (CRPS) and functional neurological disorders (FND) but until now the discussions have often been adversarial with an erroneous focus on malingering and a view of FND as 'all in the mind'. However, understanding of the nature, frequency and treatment of FND has changed dramatically in the last 10-15 years. FND is no longer assumed to be only the result of 'conversion' of psychological conflict but is understood as a complex interplay between physiological stimulus, expectation, learning and attention mediated through a Bayesian framework, with biopsychosocial predisposing, triggering and perpetuating inputs. Read More

J Physiol 2018 Nov 20;596(21):5199-5216. Epub 2018 Sep 20.

Department of Molecular Microbiology and Immunology, University of Missouri, Columbia, MO, USA.

Key Points: We developed a novel method to study sympatholysis in dogs. We showed abolishment of sarcolemmal nNOS, and reduction of total nNOS and total eNOS in the canine Duchenne muscular dystrophy (DMD) model. We showed sympatholysis in dogs involving both nNOS-derived NO-dependent and NO-independent mechanisms. Read More

Med Hypotheses 2018 Oct 29;119:41-53. Epub 2018 Jul 29.

Hunter Pain Clinic, 91 Chatham Street, Broadmeadow, NSW 2292, Australia.

Complex Regional Pain Syndrome (CRPS) has defied a clear unified pathological explanation to date. Not surprisingly, treatments for the condition are limited in number, efficacy and their ability to enact a cure. Whilst many observations have been made of physiological abnormalities, how these explain the condition and who does and doesn't develop CRPS remains unclear. Read More

World Neurosurg 2018 Nov 23;119:e235-e243. Epub 2018 Jul 23.

Department of Neurology, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seoul, Korea.

Objective: The aim of this study is to determine the risk factors affecting intraoperative neurophysiologic monitoring (IONM) changes, when such changes take place, and clinical outcomes associated with IONM change during cervical open door laminoplasty (COL) for cervical compressive myelopathy.

Methods: Between 2010 and 2015, 79 patients who underwent COL with IONM recording were studied. Changes in motor evoked potentials or somatosensory evoked potentials over an alarm criterion were defined as IONM change. Read More

Medicine (Baltimore) 2018 Jun;97(26):e11301

Department of Psychiatry, Hofstra Northwell Health-Staten Island University Hospital, Staten Island, New York.

Rationale: To present an unusual extrapyramidal motor response occurring after a sympathetic block in CRPS and its successful treatment with diphenhydramine.

Patient Concerns: Severe pain related to Complex Regional Pain Syndrome type 1 interfering with activities of daily living.

Diagnoses: Complex Regional Pain Syndrome type 1. Read More

BMC Musculoskelet Disord 2018 Jun 26;19(1):202. Epub 2018 Jun 26.

Department of Orthopaedic Surgery, Medical School, University of Minnesota, Minneapolis, MN, USA.

Background: Distal radius fractures (DRF) account for nearly one-fifth of all fractures in older adults, and women experience them 5× as often as men. Most DRF occur with low impact injuries to the wrist with an outstretched hand, and are often managed via closed treatment and cast immobilization. Women sustaining a DRF are at risk for upper limb immobility, sensorimotor changes, edema and type I complex regional pain syndrome (CRPS). Read More

Scand J Pain 2013 Oct 1;4(4):200-207. Epub 2013 Oct 1.

Pain Center, Department of Anesthesia and Intensive Care, Akademiska sjukhuset, Uppsala, Sweden.

Background and purpose This case of a 42 year old woman with lower extremity Complex Regional Pain Syndrome (CRPS) after a twisting injury of the ankle, effectively treated with the addition of mirror therapy to a rehabilitation programme, prompted a literature review of both CRPS and mirror therapy. Mirror therapy is a newer adjunct to other forms of pain control and functional restoration for treatment of CRPS as well as other difficult clinical problems. This was a required group project as part of a university based course in chronic pain for healthcare workers. Read More

Clin Neurol Neurosurg 2018 Aug 10;171:156-162. Epub 2018 Jun 10.

Department of Neurosurgery - Neurological and Neurosurgical Clinic of Joinville, Brazil. Electronic address:

Objective: Spinal cord stimulation has been proven highly effective in the treatment of Complex Regional Pain Syndrome (CRPS). The definitive implantation of a neurostimulator is usually preceded by a therapeutic test (trial), which has the purpose of identifying whether the patient would respond positively to neuromodulation or not. The present study aims to analyze the surgical results of spinal cord stimulation in type 1 CRPS patients who have not undergone trial. Read More

PLoS One 2018 13;13(6):e0198514. Epub 2018 Jun 13.

Departments of Pharmacology and Anesthesiology, New York Medical College, Valhalla, New York, United States of America.

The principal finding from this study was the recognition that the α-adrenergic antagonist, phenoxybenzamine, possesses histone deacetylase inhibitory activity. Phenoxybenzamine is approved by the United States Food and Drug Administration for the treatment of hypertensive crises associated with tumors of the adrenal medulla, pheochromocytomas. It has several "off label" indications relative to its capacity to relax vascular smooth muscle and smooth muscle of the urogenital tract. Read More

Med Sci Law 2018 Jul 4;58(3):147-155. Epub 2018 Jun 4.

2 The London School of Medicine and Dentistry, UK.

Objective The aim of this study was to review demographic and clinical characteristics of patients with complex regional pain syndrome type 1 (CRPS) seen in a UK medico-legal setting - particularly the relationship between CRPS and somatoform disorders. Methods Fifty consecutive cases of CRPS (interviewed 2005-2016) undergoing psychiatric assessment were reviewed. A systematic assessment of mental states was conducted via interview and examination of medical/psychiatric records. Read More

Bull Hosp Jt Dis (2013) 2018 Jun;76(2):123-132

Faced with a patient who presents with unexplained disproportionate pain, a surgeon may be tempted to diagnose a low pain threshold, malingering, poor coping, anxiety, or other emotional condition. However, a variety of conditions must be ruled out before the orthopedist can prescribe watchful waiting. Computed tomography and magnetic resonance imaging can detect occult fractures, acute spinal conditions or vascular occlusions, but early on are inadequate to diagnose a compartment syndrome, necrotizing fasciitis, or reflex sympathetic dystrophy (RSD). Read More

Drug Alcohol Depend 2018 07 7;188:119-125. Epub 2018 May 7.

Department of Psychology, University of Manitoba, 190 Dysart Rd, Winnipeg, MB, R3T 2N2, Canada; Department of Anesthesia and Perioperative Medicine, University of Manitoba, 2nd Floor, Harry Medovy House, 671 William Ave, Winnipeg, MB, R3E 0Z2, Canada; Department of Clinical Health Psychology, University of Manitoba, PZ350-771 Bannatyne Ave, Winnipeg, MB, R3E 3N4, Canada. Electronic address:

Background: Chronic pain conditions and posttraumatic stress disorder (PTSD) commonly co-occur and are associated with opioid use disorder (OUD). The aims of this paper were to identify prevalence estimates of OUD among individuals with and without PTSD and assess independent and combined contributions of PTSD and chronic pain conditions on OUD in a nationally representative sample.

Methods: Data were extracted from 36,309 individuals from the 2012-2013 National Epidemiologic Survey on Alcohol and Related Conditions. Read More

Prim Care 2018 Jun;45(2):289-303

Rheumatology Fellowship, San Antonio Uniformed Services Health Education Consortium (SAUSHEC), Uniformed Services University of the Health Sciences, San Antonio Military Medical Center, 3551 Roger Brooke Drive, San Antonio, TX 78234, USA.

Soft tissue musculoskeletal pain disorders are common in the primary care setting. Early recognition and diagnosis of these syndromes minimizes patient pain and disability. This article gives a brief overview of the most common soft tissue musculoskeletal pain syndromes. Read More

J Drugs Dermatol 2018 May;17(5):532-536

Reflex sympathetic dystrophy is a subtype of complex regional pain syndrome, a condition characterized by persistent post-injury extremity pain. Temperature and sweating changes, edema, mobility changes, and a variety of hair, nail, and skin sequelae have been described. Only 23 articles published since 1990 describe dermatologic changes in CRPS. Read More

J Cutan Pathol 2018 Aug 29;45(8):633-635. Epub 2018 May 29.

Department of Dermatology, Boston University School of Medicine, Boston, Massachusetts.

Creat Nurs 2018 Apr;24(1):199-201

A health educator who has reflex sympathetic dystrophy, an autoimmune condition involving chronic pain, shares her knowledge about living life to the fullest while dealing with a chronic health condition. Her advice encompasses dealing with the health care system, managing information, and obtaining physical and emotional self-care. Read More

Eur J Pain 2018 08 25;22(7):1343-1350. Epub 2018 Apr 25.

Department of Neurology, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.

Background: Complex regional pain syndrome (CRPS) is associated with deficits in limb recognition. The purpose of our study was to determine whether mental load during this task affected performance, sympathetic nervous system activity or pain in CRPS patients.

Methods: We investigated twenty CRPS-I patients with pain in the upper extremity and twenty age- and sex-matched healthy controls. Read More

A A Pract 2018 Sep;11(6):158-159

From the Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey.

Fluoroquinolones are a class of popular outpatient antimicrobial agents with a wide spectrum of therapeutic indications for respiratory and genitourinary infections. Though the most common side effects are gastrointestinal, fluoroquinolones have been increasingly associated with neurotoxicity including peripheral neuropathy and seizures. We present here a case of a 43-year-old woman with previously resolved type I complex regional pain syndrome (CRPS) who presented with symptoms of CRPS and neurotoxicity in the setting of levofloxacin administration. Read More

Pain Med 2018 Mar 9. Epub 2018 Mar 9.

Departments of **Physical Medicine and Rehabilitation.

Objective: To find and reach a consensus on the usage of ketamine in the treatment of complex regional pain syndrome and to determine a reference protocol for future studies.

Design: Three hundred fifty-one medical professionals participated in our survey on practice procedures, with 104 respondents providing information on their usage of ketamine for treating the pain associated with complex regional pain syndrome. Respondents answered questions about inpatient treatment, outpatient treatment, children vs adults, safety, and basic demographic information. Read More

Neurol Sci 2018 08 9;39(8):1487-1488. Epub 2018 Mar 9.

Department of Pharmacology, Kyungpook National University School of Medicine, Daegu, South Korea.

J Hand Surg Asian Pac Vol 2018 Mar;23(1):1-10

* Department of Orthopedic Surgery, Eulji University College of Medicine, Daejeon, Korea.

Diagnosis of Complex regional pain syndrome (CRPS) is made primarily on a clinical basis, and no specific test is known to confirm or exclude CRPS diagnosis. That is, there aren't specific diagnostic tools and instrumental tests are made only for identifying an etiology at the basis of the CRPS. Numerous therapeutic methods have been introduced, but none have shown definitive results. Read More

Curr Pain Headache Rep 2018 Feb 5;22(2):12. Epub 2018 Feb 5.

Jefferson Pain Center, Department of Anesthesiology, Thomas Jefferson University, Philadelphia, USA.

Purpose Of Review: Complex regional pain syndrome (CRPS) is a painful debilitating neurological condition that accounts for approximately 1.2% of adult chronic pain population. Ketamine, an NMDA receptor antagonist, is an anesthetic agent that has been used by some pain specialists for CRPS. Read More

Curr Pain Headache Rep 2018 Feb 1;22(1). Epub 2018 Feb 1.

Department of Anesthesiology, Duke University Medical Center, Durham, NC, 27710, USA.

Purpose Of Review: To describe the current understanding of the role of three-phase bone scintigraphy (TPBS) in the diagnosis and management of complex regional pain syndrome (CRPS), discuss its advantages and limitations, and present three examples of TPBS patterns typically seen in CRPS patients.

Recent Findings: CRPS is a debilitating disorder frequently presenting with pain to ordinarily non-painful stimuli, redness, swelling, following fractures, stroke, myocardial infarction, surgery, or even minor trauma, and its diagnosis, based on clinical criteria and supportive imaging findings, is difficult. Of the available adjunctive diagnostic imaging modalities, radionuclide bone scintigraphy using a TPBS protocol is the most sensitive and specific for detecting abnormalities commonly seen with this condition-classically, increased periarticular uptake on delayed phase of TPBS, with variable increased uptake on perfusion phases, depending on chronicity. Read More

J Okla State Med Assoc 2017 04;110(4):202-4

A 33 year-old female at 38 weeks gestation with a history of Complex Regional Pain Syndrome (CRPS) Type 1 of the upper extremities, diagnosed 13 years prior to this admission, was scheduled for an elective cesarean section (C-Section). She refused neuraxial anesthesia and requested general anesthesia. This abstract discusses the general anesthesia steps taken to pre-empt recurrence of CRPS symptoms. Read More

Medicine (Baltimore) 2017 Dec;96(49):e9027

Department of Orthopedic Surgery, The Third Hospital of Hebei Medical University, Shijiazhuang, China.

Background: The relative efficacy of operative and nonoperative treatments for the displaced intra-articular calcaneal fractures (DIACF) remains uncertain.

Object: We conducted a meta-analysis to compare the effectiveness of operative and nonoperative treatments in treating patients with DIACF.

Methods: Databases including Cochrane Library, Medline, Embase, CBM, CNKI, and Google Scholar were searched. Read More

Zhongguo Zhen Jiu 2017 Feb;37(2):121-124

Rehabilitation Department, Tianshan TCM Hospital of Changning District, Shanghai 200051.

Objective: To compare the effects between penetration acupuncture at Baxie (EX-UE 9) combined with rehabilitation and simple rehabilitation for swelling hand in post-stroke shoulder-hand syndrome.

Methods: Sixty patients were randomly assigned into an observation group and a control group,30 cases in each one. Penetration acupuncture at Baxie (EX-UE 9) combined with rehabilitation were used in the observation group,and the acupoints were the affected Baxie (EX-UE 9) and Wailaogong (EX-UE 8). Read More

Nefrologia 2018 Jan - Feb;38(1):99-101. Epub 2017 Dec 6.

Unidad de Trasplante Renal, Hospital Clínic, Barcelona, España.

Workplace Health Saf 2018 Apr 9;66(4):169-172. Epub 2017 Nov 9.

1 California State University, Monterey Bay.

A 36-year-old woman sustained a Grade 2 ankle sprain at work. Two days after the injury, the ankle and foot became red and she complained of "intense burning pain." First diagnosed with complex reflex sympathetic dystrophy, the employee was prescribed medications that provided some pain relief; a subsequent temporary nerve block provided additional relief. Read More

Acta Ortop Bras 2017 Sep-Oct;25(5):194-196

. Department of Research, Unidad Médica de Alta Especialidad "Dr. Victorio de la Fuentes Narváez", Instituto Mexicano del Seguro Social, Mexico City, Mexico.

Objective: The aim of this study was to identify factors associated with developing complex regional pain syndrome (CRPS) after surgical treatment for distal radius fracture (DRF).

Methods: This case-control study analyzed patients seen from January 2014 to January 2016. Results: In our sample of 249 patients, 4% developed CRPS. Read More

Hand (N Y) 2017 Oct 1:1558944717735949. Epub 2017 Oct 1.

1 University of Virginia Health System, Charlottesville, USA.

Background: Complex regional pain syndrome (CRPS) can be a devastating complication following extremity injury, but risk factors are not well understood. The purpose of this study was to investigate the association between fibromyalgia and the development of CRPS after distal radius fracture.

Methods: The PearlDiver Medicare database was queried using International Classification of Diseases, 9th Revision (ICD-9) and Current Procedural Terminology (CPT) codes for diagnoses and treatments of distal radius fractures. Read More

Pain Physician 2017 09;20(6):E807-E822

Laboratory of Preclinical and Surgical Studies, Rizzoli Orthopedic Institute, Bologna, Italy.

Background: Complex regional pain syndrome type I (CRPS-I), also called algodystrophy, is a complex syndrome characterized by limb pain, edema, allodynia, hyperalgesia and functional impairment of bone with a similar clinical picture of osteoporosis, including an increased release of various pro-inflammatory neuropeptides and cytokines. Several treatments have been proposed for CRPS-I, but due to the poor outcome of conventional drugs and the invasiveness of some techniques, expectations are now directed towards new resources that could be more effective and less invasive.

Objective: In the light of preclinical evidence, which underlined pulsed electromagnetic fields' (PEMFs) properties on osteoblasts (OBs), osteoclasts (OCs), and pathologies with an inflammatory profile, the present review aims to investigate whether there is a rationale for the use of PEMFs, as a combined approach, in CRPS-I. Read More

Presse Med 2017 Nov 14;46(11):1107-1110. Epub 2017 Sep 14.

CHU Hassan II de Fès, service de traumato-orthopédie A, 30000 Fès, Maroc.

Toxins (Basel) 2017 09 15;9(9). Epub 2017 Sep 15.

Department of Anesthesiology and Pain Medicine, College of Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul 06591, Korea.

Neuropathic pain in a chronic post-ischaemic pain (CPIP) model mimics the symptoms of complex regional pain syndrome type I (CRPS I). The administration of bee venom (BV) has been utilized in Eastern medicine to treat chronic inflammatory diseases accompanying pain. However, the analgesic effect of BV in a CPIP model remains unknown. Read More

Clin Rehabil 2018 Apr 13;32(4):429-439. Epub 2017 Sep 13.

1 Center for Evidence-Based Medicine and Clinical Research, Taihe Hospital, Hubei University of Medicine, Shiyan, Hubei Province, China.

Objective: To investigate the effectiveness of traditional manual acupuncture combined with rehabilitation therapy versus rehabilitation therapy alone for shoulder hand syndrome after stroke.

Data Sources: PubMed, EMBASE, the Cochrane Library, Chinese Biomedicine Database, China National Knowledge Infrastructure, VIP Information Database, Wan Fang Database and reference lists of the eligible studies were searched up to July 2017 for relevant studies.

Methods: Randomized controlled trials that compared the combined effects of traditional manual acupuncture and rehabilitation therapy to rehabilitation therapy alone for shoulder hand syndrome after stroke were included. Read More

Scand J Pain 2016 Oct 16;13:156-163. Epub 2016 Jun 16.

Pain Innovations Inc., London, Ontario, Canada.

Background: Treatment of neuropathic pain in children is challenging, and requires a multimodal approach of pharmacologic, physical, and psychological therapies; however there is little evidence to guide practice. Amitriptyline and gabapentin are first-line drugs for treating neuropathic pain in adults, yet no studies have examined their efficacy, or compared them directly, to determine which might be better for pain relief and sleep disturbance in children.

Methods: After informed consent was obtained, 34 patients aged 7-18 years diagnosed with complex regional pain syndrome type I (CRPS I) or a neuropathic pain condition were randomly allocated to receive either amitriptyline or gabapentin. Read More

Scand J Pain 2017 01 22;14:84-88. Epub 2016 Nov 22.

Department of Orthopaedic Surgery, Wake Forest School of Medicine, Medial Center Boulevard, Winston-Salem, NC 27157, United States. Electronic address:

Background And Purpose: Complex regional pain syndrome (CRPS) is a challenging complication after surgery or trauma. This study sought to determine the incidence of CRPS after a second inciting event in a previously unaffected extremity in patients with a history of an ongoing CRPS diagnosis in another extremity.

Methods: A retrospective review identified patients with CRPS seen in clinic over a 20-month period. Read More

Scand J Pain 2017 04 30;15:113-114. Epub 2017 Mar 30.

Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany. Electronic address:

Clin Nucl Med 2017 Oct;42(10):784-786

From the *Department of Radiology, Saitama Municipal Hospital, Saitama; and †Department of Radiology, Keio University School of Medicine, Tokyo, Japan.

A 64-year-old man with lung cancer with a history of revascularization of the occluded right femoral artery underwent bone scintigraphy, which showed intense uptake in the distal side of the right leg. The additional SPECT/CT clarified that the uptake was predominantly increased in the epiphyses of the right ankle and foot with possible osteopenia. One month later, follow-up SPECT/CT showed the manifestation of periosteal resorption in the hypermetabolic sites with slight decrease in bone metabolism. Read More

Indian J Orthop 2017 Jul-Aug;51(4):455-460

Department of Orthopaedics, Indraprastha Apollo Hospitals, New Delhi, India.

Background: Transient osteoporosis of the hip (TOH) is a poorly understood and forgotten clinical entity. The diagnosis is often delayed, and inappropriate treatment is provided, due to the lack of its awareness among the clinicians.

Materials And Methods: Twelve patients (11 male and one female) within the age group of 35-50 years, were identified retrospectively from the hospital records between July 2011 and June 2015 who had evidence of TOH on clinical and radiological parameters. Read More

Hand (N Y) 2017 11 1;12(6):535-540. Epub 2017 Feb 1.

2 William Beaumont Army Medical Center, Fort Bliss, TX, USA.

Background: Posterior interosseous nerve neurectomies (PINN) are an option in the treatment of chronic dorsal wrist pain. However, the literature describing PINN consists primarily of small case series, and the procedure is typically done as an adjunct treatment; therefore, the outcomes of the PINN itself are not well known. We performed a systematic review of the literature to provide characteristics of patients following a PINN. Read More