286 results match your criteria Recent Patents on Biotechnology [Journal]


Potential Angiotensin Converting Enzyme Inhibitors from Moringa oleifera.

Recent Pat Biotechnol 2019 Feb 10. Epub 2019 Feb 10.

Faculty of applied sciences and biotechnology, Shoolini university of biotechnology and management sciences, Solan-173229, Himachal Pradesh. India.

Background: Hypertension is the chronic medical condition and it affect billions of people worldwide. Natural medicines are the main alternatives of treatment for a large majority of people suffering from hypertension. Niazicin-A, Niazimin-A, and Niaziminin-B compounds were reported from Moringa oleifera ethanolic leave extract having potential antihypertensive activity. Read More

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http://dx.doi.org/10.2174/1872208313666190211114229DOI Listing
February 2019
1 Read

Nucleic acid therapeutics in Huntington's disease.

Recent Pat Biotechnol 2019 Feb 8. Epub 2019 Feb 8.

Department of Biotechnology, National Institute of Pharmaceutical Education and Research (NIPER), Sector 67, S.A.S. Nagar, Punjab 160062. India.

Background: Protein misfolding is a critical factor in the progression of a large number of neurodegenerative diseases. The incorrectly folded protein is prone to aggregation, leading in aberrant interaction with other cellular proteins, elevated oxidative stress, impaired cellular machinery, finally resulting in cell death. Due to its monogenic origin, Huntington's disease (HD) is a poster child of protein misfolding neurodegenerative disorders. Read More

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http://dx.doi.org/10.2174/1872208313666190208163714DOI Listing
February 2019
9 Reads

Exploring the patent landscape of RNAi-based innovation for plant breeding.

Recent Pat Biotechnol 2019 Feb 4. Epub 2019 Feb 4.

Department of Environmental Science and Policy, Università degli Studi di Milano, Milano. Italy.

Background: RNA interference (RNAi) is an innovative technique for plant improvement based on naturally occurring mechanisms that shows great potential because of its high specificity and possibility to be applied through innovative methods of topical application in plants. This specific innovation sector is worth analysing from the economic perspective given the great potentiality of RNAi-based plants and product to support modern agriculture in reaching the goals for the improvement of agri-food chains global sustainability. This paper aims to evaluate the global landscape of RNAi innovation by analysing patent data as indicators of innovation output. Read More

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http://dx.doi.org/10.2174/1872208313666190204121109DOI Listing
February 2019

Ammonia sensing and cytotoxicity of biosynthesized silver nanoparticle by Arabic Gum (AG).

Recent Pat Biotechnol 2019 Jan 18. Epub 2019 Jan 18.

Nuclear Medicine Research Center, Mashhad University of Medical Sciences, Mashhad. Iran.

Background: The green synthesizing procedure of Silver nanoparticles (AgNPs) has been performed through the usage of a natural polysaccharide; Arabic gum (AG) as a stabilizing/capping agent. For characterization of AgNPs, TEM, particle size analyzer and UV-Vis were used.

Methods: The aim of our project was to identify biosynthesized AgNPs for sensing ammonia and to explore its toxicity on Neuro-2A cells. Read More

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http://www.eurekaselect.com/169123/article
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http://dx.doi.org/10.2174/1872208313666190118123141DOI Listing
January 2019
7 Reads

Patent Selections.

Authors:

Recent Pat Biotechnol 2018 ;12(4):299-301

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http://dx.doi.org/10.2174/187220831204181221102714DOI Listing
January 2018
1 Read

Use of Enzymes as Tools in Industrial Processes.

Authors:
D V Gokhale

Recent Pat Biotechnol 2018 ;12(4):297-298

NCIM Resource Center, CSIR-National Chemical Laboratory, Pune, Maharashtra, India.

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http://dx.doi.org/10.2174/187220831204181221102552DOI Listing
January 2019
1 Read

Recent Patents applications in red biotechnology: A mini-review.

Recent Pat Biotechnol 2019 Jan 14. Epub 2019 Jan 14.

Microbial Biotechnology Laboratory, University Federal of Sao Joao del Rei, São João del Rei - MG, Divinópolis, MG, 35501-296. Brazil.

The different fields of biotechnology can be classified by colors, as a "rainbow" methodology; In this sense, the red biotechnology, is focused on the preservation of health, has been outstanding in helping to solve this challenge through the provision of technologies, including diagnostic kits, molecular diagnostics, vaccines, innovations in cancer research, therapeutic antibodies and stem cells. In this work, we revised some patents regarding to red biotechnology as examples to covers this subject. Read More

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http://dx.doi.org/10.2174/1872208313666190114150511DOI Listing
January 2019
7 Reads

In silico analysis of different signal peptides for secretory production of arginine deiminase in Escherichia coli.

Recent Pat Biotechnol 2018 Dec 31. Epub 2018 Dec 31.

Department of Pharmaceutical Biotechnology, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz. Iran.

Background: Secretory production of recombinant protein in bacterial hosts fulfill several advantages. Selecting an appropriate secretory signal peptide is a critical step in secretory production of different protein. Several patents report the usage of signal peptides for secretory production of recombinant proteins in E. Read More

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http://www.eurekaselect.com/168683/article
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http://dx.doi.org/10.2174/1872208313666190101114602DOI Listing
December 2018
2 Reads

Arginine Deiminase: Current Understanding and Applications.

Recent Pat Biotechnol 2018 Dec 20. Epub 2018 Dec 20.

Department of Pharmaceutical Biotechnology, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz. Iran.

Background: Arginine deiminase (ADI), an arginine catabolizing enzyme, is considered as an anti-tumor agent for the treatment of arginine auxotrophic cancers. However, some obstacles limit its clinical applications.

Objective: This review will summarize the clinical applications of ADI, from a brief history to its limitations, and will discuss the different ways to deal with the clinical limitations. Read More

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http://dx.doi.org/10.2174/1872208313666181220121400DOI Listing
December 2018
1 Read

Patents on quantitative susceptibility mapping (QSM) of tissue magnetism.

Recent Pat Biotechnol 2018 Dec 16. Epub 2018 Dec 16.

Department of Radiology, Weill Medical College of Cornell University, New York. United States.

Background: Quantitative susceptibility mapping (QSM) depicts biodistributions of tissue magnetic susceptibility sources, including endogenous iron and calcifications, as well as exogenous paramagnetic contrast agents and probes. When comparing QSM with simple susceptibility weighted MRI, QSM eliminates blooming artifacts and shows reproducible tissue susceptibility maps independent of field strength and scanner manufacturer over a broad range of image acquisition parameters. For patient care, QSM promises to inform diagnosis, guide surgery, gauge medication, and monitor drug delivery. Read More

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http://dx.doi.org/10.2174/1872208313666181217112745DOI Listing
December 2018
1 Read

Development insights of surface modified lipid nanoemulsions of dihydroartemisinin for malaria chemotherapy: characterization, and in vivo antimalarial evaluation.

Recent Pat Biotechnol 2018 Dec 3. Epub 2018 Dec 3.

Drug Delivery and Nanomedicines Research Group, Department of Pharmaceutics, Faculty of Pharmaceutical Sciences, University of Nigeria, Nsukka 410001, Enugu State. Nigeria.

Background: The use of dihydroartemisinin (DHA) for effective malaria treatment is challenged by its poor aqueous solubility and inadequate bioavailability leading to treatment failures and emergence of resistant strains. A review of some novel drug delivery systems developed to address these challenges and their patents revealed that no study has reported the application of surface modified lipid nanoemulsions for improved antimalarial activity of DHA.

Objective: The main thrust of this study is to develop oral dihydroartemisinin formulations solubilized in surface modified lipid nanoemulsions, characterize, and evaluate their activity against murine malaria Methods: Lipid nanoemulsions containing dihydroartemisinin were formulated by high pressure homogenization using soybean oil, and polyethylene glycol 4000 was employed for surface modification. Read More

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http://dx.doi.org/10.2174/1872208313666181204095314DOI Listing
December 2018
2 Reads

Cryopreservation Of Orchids - A Review.

Authors:
Saranjeet Kaur

Recent Pat Biotechnol 2018 Nov 27. Epub 2018 Nov 27.

Department of Applied Sciences, Chandigarh University, Gharuan, Distt.- Mohali, Punjab. India.

Background: The orchids are one of the beautiful creations of nature which stand apart from any other assemblage of flowering plants. They are highly evolutionary and ecologically significant group of plants that have effectively occupied almost every habitat on the earth. Indiscriminate collections and extermination of their natural habitats have threatened many species of orchids with extinction, resulting into severe reduction of their genetic resources in nature. Read More

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http://dx.doi.org/10.2174/1872208313666181127143058DOI Listing
November 2018
2 Reads

Lipases: Sources, Production, Purification, and Applications.

Recent Pat Biotechnol 2018 Oct 28. Epub 2018 Oct 28.

Department of Civil Engineering, NIT Agartala, Agartala-799046. India.

Background and sources: Lipase enzyme is a naturally occurring enzyme found in the stomach and pancreatic juice. They function is to digests fats and lipids, helping to maintain correct gallbladder function. Lipase is the one such widely used and versatile enzyme. Read More

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http://dx.doi.org/10.2174/1872208312666181029093333DOI Listing
October 2018
28 Reads

Isolation, purification, characterisation and application of L-ASNase (L-ASNase): A review.

Recent Pat Biotechnol 2018 Oct 12. Epub 2018 Oct 12.

Department of Chemical Engineering, National Institute of Technology Agartala. India.

Background: L-ASNase (L-asparagine aminohydrolase EC 3.5.1. Read More

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http://dx.doi.org/10.2174/1872208312666181012150407DOI Listing
October 2018
2 Reads

Computational Fluid Dynamics (CFD) Simulation of Cross-flow mode operation of Membrane for downstream processing.

Recent Pat Biotechnol 2018 Sep 24. Epub 2018 Sep 24.

Department of Civil Engineering, NIT Agartala, Jirania, Tripura (W) 799046. India.

Background: Membrane filtration process produced good quality of permeate flux due to which it is used in different industries like dairy, pharmaceutical, sugar, starch and sweetener industry, bio separation, purification of biomedical materials, and downstream polishing etc. The cross flow mode of operation has also been used to improve the quality of the Rubber Industrial effluent of Tripura, India.

Methods: The Computational Fluid Dynamics (CFD) simulation of the cross flow membrane is done by using ANSYS Fluent 6. Read More

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http://dx.doi.org/10.2174/1872208312666180924160017DOI Listing
September 2018
1 Read

Biotechnological Applications of Serine Proteases: A Patent Review.

Recent Pat Biotechnol 2018 ;12(4):280-287

UMR 1319 Micalis, INRA, AgroParisTech, Universite Paris-Saclay, Microbiota Interaction with Human and Animal Team, 78350, Jouy-en-Josas, France.

Background: Serine proteases have long been recognized to play key roles in various physiological processes. However, their disequilibrium can be linked to several diseases. Taking into account their wide diversity and specificity, they have been actively investigated by many industrial, academic and pharmaceutical industries. Read More

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http://www.eurekaselect.com/165586/article
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http://dx.doi.org/10.2174/1872208312666180924112007DOI Listing
January 2019
3 Reads

Optimization of process parameters for production of pectinase using Bacillus Subtilis MF447840.1.

Recent Pat Biotechnol 2018 Sep 16. Epub 2018 Sep 16.

Division of Biological Sciences and Engineering, Netaji Subhas Institute of Technology, New Delhi-110078. India.

Background: Pectinase enzyme has immense industrial prospects in food and beverage industries. We mentioned the patents relating to pectinase used in various industries.

Objective: In this study, the optimization of the process parameters for the pectinase production was carried out from Bacillus Subtilis MF447840. Read More

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http://dx.doi.org/10.2174/1872208312666180917094428DOI Listing
September 2018
18 Reads

Propolis and its Dental Applications: A Technological Prospection.

Recent Pat Biotechnol 2018 ;12(4):288-296

Departament of Pharmacy, College of Pharmacy, Odontology and Nursing, Federal University of Ceara, Fortaleza/ CE, Brazil.

Background: Propolis is a resinous complex produced by Apis mellifera L. bees whose variety of pharmacological properties results from the complexity of its composition. In dentistry, propolis is used on the prevention of oral diseases such as dental caries and gingivitis. Read More

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http://dx.doi.org/10.2174/2211550107666180815114855DOI Listing
January 2019
1 Read

Mode of Action, Properties, Production, and Application of Laccase: A Review.

Recent Pat Biotechnol 2018 Aug 21. Epub 2018 Aug 21.

Department of Civil Engineering, NIT Agartala, Agartala-799046. India.

Background and Source: Laccase belongs to the blue multi-copper oxidases, which are widely distributed in fungi and higher plants. It is present in Ascomycetes, Deuteromycetes, and Basidiomycetes and found abundantly in white-rot fungi.

Applications: Laccase enzyme because of their potential have acquired more importance and application in the area of textile, pulp and paper, and food industry. Read More

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http://dx.doi.org/10.2174/1872208312666180821161015DOI Listing
August 2018
37 Reads

CFD and Optimization Study of Frictional Pressure drop through Bends.

Recent Pat Biotechnol 2018 Aug 20. Epub 2018 Aug 20.

Department of Mathematics, NIT, Agartala, Tripura (W), Jirania, Pin-799046. India.

Background: The non-Newtonian pseudoplastic liquid flow through different types of the bend is more complicated compared to the simple straight pipe as the bends are associated with various curve geometry. Bends have wide application in bioengineering, biotechnology and biomedical such as study biofluids, blood rheology study, the design of medical equipment like equipment measuring the cholesterol etc. Methods:The papers deal with the estimation of loss coefficient and frictional pressure drop of Newtonian and non-Newtonian pseudoplastic fluid flow through the different bend of 0. Read More

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http://dx.doi.org/10.2174/1872208312666180820153706DOI Listing
August 2018
2 Reads

Carcinoembryonic Antigen (CEA) and Hepatic Metastasis in Colorectal Cancer: Update on Biomarker for Clinical and Biotechnological Approaches.

Recent Pat Biotechnol 2018 ;12(4):269-279

Department of Genetics and Morphology, Institute of Biology, University of Brasilia, Brasilia -DF, Brazil.

Background: Carcinoembryonic Antigen (CEA) is a recommended prognostic marker in Colorectal Cancer (CRC) for tumor diagnosis and monitoring response to therapy. High CEA levels are specifically associated with CRC progression and increased levels of the marker are expected to fall following surgical treatment. Due to its role in CRC, CEA has also been explored as a target for cancer therapy and diagnosis approaches. Read More

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http://dx.doi.org/10.2174/1872208312666180731104244DOI Listing
January 2019
1 Read

Patent Landscape on Structured Lipids Produced by Enzyme Technology.

Recent Pat Biotechnol 2018 ;12(4):252-268

Laboratory of Food Science and Nutritional Biochemistry, Institute of Chemistry, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.

Background: Lipid modification results in several benefits for the food industry, biotechnology advances and human health. Customizing bioactive lipids is very appealing because it improves the product's nutritional quality. Lipases are sustainable biocatalysts that can be reused, show selectivity towards substrates and reactions occur in mild conditions. Read More

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http://dx.doi.org/10.2174/1872208312666180604095717DOI Listing
January 2019
1 Read

Geochemical Cycle of Radon and its Bioremediation Opportunity from Water Environment: A Review.

Recent Pat Biotechnol 2018 ;12(4):239-251

CSIR-Institute of Minerals and Materials Technology, Bhubanrswar-751013, India.

Background: The waterborne or airborne radon causes carcinogenesis in the human bodies due to the continuous decay of α- and β- particles. The health risks related to radioactive radon instigate to develop an advanced technology for its removal from the environment. There are two standard techniques, such as aeration and activated carbon filtration, available for its removal. Read More

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http://www.eurekaselect.com/161742/article
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http://dx.doi.org/10.2174/2211550107666180501123246DOI Listing
January 2019
3 Reads

Lateral Flow Assay for Interleukin 6: A Technological and Scientific Prospection of a 10-Year Survey.

Recent Pat Biotechnol 2018 ;12(3):221-228

Universidade Federal do Piaui, Teresina-PI, Brazil.

Background: Interleukin-6 (IL-6) is a multifunctional cytokine that plays a crucial role not only in the immune system but also in numerous biological processes. Elevated IL-6 levels have been observed in many types of cancer and inflammatory diseases. Among the techniques that have been used to quantify IL-6, a Lateral Flow Assay (LFA) is one of the most promising. Read More

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http://dx.doi.org/10.2174/1872208312666180321113248DOI Listing
November 2018
7 Reads

Novel Genetic Tool to Study the Stability of Genomic Islands.

Recent Pat Biotechnol 2018 ;12(3):200-207

Translational Health Science and Technology Institute, NCR Biotech Science Cluster, Faridabad, India.

Background: Genomic islands (GIs) are discrete segments of mobile DNA with defined boundaries according to recent patents, acquired in the bacterial genome from another organism by horizontal gene transfer during the course of evolution. GIs contribute significantly to virulence, disease development, antimicrobial resistance and metabolic process.

Objective: The present study focuses on the development of a vector based genetic tool carrying selectable and counter-selectable markers, in order to flag the GIs in the bacterial chromosome and monitor their stability under in vitro and in vivo conditions. Read More

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http://dx.doi.org/10.2174/1872208312666180223113618DOI Listing
November 2018
3 Reads

Exploration of Global Trend on Biomedical Application of Polyhydroxyalkanoate (PHA): A Patent Survey.

Recent Pat Biotechnol 2018 ;12(3):186-199

Department of Biomedical Sciences, Faculty of Medicine, MAHSA University, (Saujana Putra Campus), Selangor- 41200, Darul Ehsan, Malaysia.

Background: Polyhydroxyalkanoates are bio-based, biodegradable naturally occurring polymers produced by a wide range of organisms, from bacteria to higher mammals. The properties and biocompatibility of PHA make it possible for a wide spectrum of applications. In this context, we analyze the potential applications of PHA in biomedical science by exploring the global trend through the patent survey. Read More

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http://dx.doi.org/10.2174/1872208312666180131114125DOI Listing
November 2018
3 Reads

Distribution and Characterization of the Vitis vinifera L. subsp sylvestris in Southern Tuscany.

Recent Pat Biotechnol 2018 ;12(3):208-220

Department of Life Sciences, University of Siena, Siena, Italy.

Background: The Eurasian grapevine is the most widespread fruit crop in the world. Numerous studies have focused on clarifying the events of domestication and the geographical areas in which they occurred.

Objectives: In order to add upon information on the process of grapevine domestication, the distribution and genetic diversity of a small, wild population localized in Poggio Ghiaccio Forte, an archaeological site in Maremma (Southern Tuscany), were assessed. Read More

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http://dx.doi.org/10.2174/1872208312666180125102138DOI Listing
November 2018
22 Reads

Evaluation of Fibroblasts Cells Viability and Adhesion on Six Different Titanium Surfaces: An in vitro Experimental Study.

Recent Pat Biotechnol 2018 ;12(2):145-153

Biotecnos Research Center, Montevideo, Uruguay, University Catholica San Antonio de Murcia (UCAM), Murcia, Spain.

Background: The topographical surficial characteristics and properties of materials can induce different cell reactions regarding the viability and adhesion according to the recent patents. The aim of this in vitro experimental study was to evaluate the viability and adhesion of fibroblastic cells seeded on titanium disks with different surface topography. In addition, we revised all patents related to surface treatment of dental implants. Read More

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http://dx.doi.org/10.2174/1872208312666180101165807DOI Listing
October 2018
11 Reads

Nerolidol and its Pharmacological Application in Treating Neurodegenerative Diseases: A Review.

Recent Pat Biotechnol 2018 ;12(3):158-168

Federal University of Piaui, CEP 64049-550, Teresina, Piaui, Brazil.

Background: Research on natural bioactive compounds has increased exponentially over the last decades. The discovery of new phytochemicals that possess pharmaceutical properties is useful in the development of therapeutic alternatives. The nerolidol (3,7,11-trimetil-1,6,10-dodecatrien-3-ol or 3,7,11-trimetildodeca-1,6,10-trien-3-ol) has been extensively studied for its therapeutic potential because of its pharmacological activities in the treatment of neurodegenerative diseases. Read More

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http://dx.doi.org/10.2174/1872208312666171206123805DOI Listing
November 2018
5 Reads

Impact of Electron-Beam Irradiation on Functional Attributes of Seeds of Two Coastal Wild Legume Landraces of Canavalia.

Recent Pat Biotechnol 2018 ;12(3):177-185

Department of Biosciences, Mangalore University, Mangalagangotri, Mangalore 574199, Karnataka, India.

Background: Vegetable proteins have widespread application in the food industry as functional ingredients in food formulations according to the recent patents. Requirement to develop less expensive protein-rich supplementary foods has resulted in shift of emphasis towards lesser known wild than popular legumes.

Objective: The aim of this study is to expose seeds of two coastal sand dune wild legumes of the Southwest India (Canavalia cathartica and C. Read More

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http://dx.doi.org/10.2174/1872208311666171129162108DOI Listing
November 2018
6 Reads

The Ecstacy of Gold: Patent Expirations for Trastuzumab, Bevacizumab, Rituximab, and Cetuximab.

Recent Pat Biotechnol 2018 ;12(2):101-112

Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of California, Irvine-Medical Center, Orange, CA, United States.

Objective: Fully humanized monoclonal antibodies have revolutionized the treatment of many solid tumors, including ovarian, lung, colorectal, and breast cancer. Among the most widely used monoclonal antibodies in clinical oncology are cetuximab, trastuzumab, rituximab, and bevacizumab.

Methods: This is a review article focusing on the drug patents for cetuximab, trastuzumab, rituximab, and bevacizumab. Read More

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http://dx.doi.org/10.2174/1872208311666171122152131DOI Listing
October 2018
9 Reads

Relevant Patented Biotechnological Applications of Ecotin: An Update.

Recent Pat Biotechnol 2018 ;12(4):233-238

UMR 1319 Micalis, INRA, AgroParisTech, Universite Paris-Saclay, Microbiota Interaction with Human and Animal Team, 78350, Jouy-en-Josas, France.

Background: Ecotins are serine protease inhibitors which are generally found in the periplasmic compartment. These inhibitors act on a wide range of serine proteases with different efficiencies. Actually, only few Ecotins were studied, and the main characterized proteins were derived from Escherichia coli. Read More

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http://dx.doi.org/10.2174/1872208311666171122153908DOI Listing
January 2019
12 Reads

Computational Determination of the Effects of Bacteriophage Bacteriophage Interactions in Human Body.

Recent Pat Biotechnol 2018 ;12(3):169-176

Department of Computer Science, Faculty of Computers and Information, Cairo University, Cairo, Egypt.

Background: Chronic diseases are becoming more serious and widely spreading and this carries a heavy burden on doctors to deal with such patients. Although many of these diseases can be treated by bacteriophages, the situation is significantly dangerous in patients having concomitant more than one chronic disease, where conflicts between phages used in treating these diseases are very closer to happen.

Method: This research paper presents a method to detecting the Bacteriophage-Bacteriophage Interaction. Read More

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http://dx.doi.org/10.2174/1872208311666171019155230DOI Listing
November 2018
3 Reads

Editorial: Patents on Decontamination of Heavy Metals from Environment.

Recent Pat Biotechnol 2017 ;11(3):154

Post doc, Wangs Lab, Department of Nano-Engineering University of California, San Diego (UCSD) SME Building, Lab- 209 9500 Gilman Drive, La Jolla, CA 92093-0448, USA

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http://dx.doi.org/10.2174/187220831103170914162347DOI Listing
January 2017
8 Reads

Biofactories for the Production of Recombinant Phytases and their Application in the Animal Feed Industry.

Recent Pat Biotechnol 2018 ;12(2):113-125

Microbial Biotechnology Laboratory, Universidade Federal de Sao Joao Del-Rei, Divinópolis, MG, Brazil.

Background: Phytases are enzymes capable of degrading phytic acid and are used in animal feed supplementation in order to improve digestibility through the release of minerals such as phosphorus. Recent inventions show interest in production and optimization of recombinant phytases with biochemical and physicochemical characteristics promising for animal feed industry.

Methods: This review article is focused on relevant patents of promising phytases, together with the commonly used expression systems for their production and tools currently employed to generate new phytases. Read More

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http://dx.doi.org/10.2174/1872208311666170915161848DOI Listing
October 2018
18 Reads

Toward Enhancing the Enzymatic Activity of a Novel Fungal Polygalacturonase for Food Industry: Optimization and Biochemical Analysis.

Recent Pat Biotechnol 2018 ;12(2):134-144

Department of Industrial Biotechnology, Genetic Engineering and Biotechnology Research Institute, University of Sadat City (USC), Sadat City, Egypt.

Background: The review of literature and patents shows that enhancing the polygalacturonase (PG) production and activity are still required to fulfill the increasing demands.

Methods: A dual optimization process, which involved Plackett-Burman design (PBD), with seven factors, and response surface methodology, was applied to optimize the production of extracellular PG enzyme produced by a novel strain of Aspergillus flavus isolated from rotten orange fruit. The fungal PG was purified and biochemically characterized. Read More

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http://www.eurekaselect.com/154900/article
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http://dx.doi.org/10.2174/1872208311666170811124417DOI Listing
October 2018
26 Reads

High-Performance Enzyme-Free Glucose Sensor with Co-Cu Nanorod Arrays on Si Substrates.

Recent Pat Biotechnol 2018 ;12(2):126-133

Bioengineering Research Group, Nanotechnology and Advanced Materials Department, Materials and Energy Research Centre (MERC), Tehran, Iran.

Background: Glucose sensors have been extensively researched in patent studies and manufactured a tool for clinical diabetes diagnosis. Although some kinds of electrochemical enzymatic glucose sensors have been commercially successful, there is still room for improvement, in selectivity and reliability of these sensors. Because of the intrinsic disadvantages of enzymes, such as high fabrication cost and poor stability, non-enzymatic glucose sensors have recently been promoted as next generation diagnostic tool due to their relatively low cost, high stability, prompt response, and accuracy. Read More

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http://dx.doi.org/10.2174/1872208311666170713150220DOI Listing
October 2018
19 Reads

Microbial Lipase Mediated by Health Beneficial Modification of Cholesterol and Flavors in Food Products: A Review.

Recent Pat Biotechnol 2018 ;12(2):81-91

Department of Basic Sciences, Microbiology Laboratory, Dr. Yashwant Singh Parmar University of Horticulture and Forestry, Nauni, Solan, H.P., 173230, India.

Background: The tremendous need of lipase for varied applications in biotechnology increases its economical value in food and allied industries. Patents suggest that lipase has an impressive number of applications viz. enhancements of flavor in food products (Cheese, butter, alcoholic beverages, milk chocolate and diet control food stuffs), detergent industry in removing oil, grease stain, organic chemical processing, textile industry, oleochemical industry, cosmetic industry and also as therapeutic agents in pharmaceutical industries. Read More

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http://dx.doi.org/10.2174/1872208311666170615094552DOI Listing
October 2018
5 Reads

Converting Enzymes into Tools of Industrial Importance.

Recent Pat Biotechnol 2018 ;12(1):33-56

Department of Biotechnology, National Institute of Pharmaceutical Education and Research, Sector 67, S.A.S. Nagar, Punjab 160062. India.

Background: Enzymes have applications in numerous biotechnological products and processes that are commonly used in the production of food and beverages, cleaning supplies, clothing, paper products, transportation fuels, pharmaceuticals, and monitoring devices. Enzymes, however, are optimized to function under physiological conditions. Any change in reaction conditions results in their activity as well as stability being compromised. Read More

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http://dx.doi.org/10.2174/1872208311666170612113303DOI Listing
July 2018
3 Reads

Recent Technology Development for the Biosynthesis of Human Milk Oligosaccharide.

Recent Pat Biotechnol 2018 ;12(2):92-100

School of Chemical and Biomolecular Engineering, Georgia Institute of Technology, Atlanta-30332, GA, United States.

Background: Human milk oligosaccharide (HMO) is a third most abundant component in breast milk. HMOs are molecules naturally tailored to the need of an infant. They protect infants from diseases, foster healthy gastrointestinal systems, reinforce fledgling immune function, and promote early brain development. Read More

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http://dx.doi.org/10.2174/1872208311666170531110721DOI Listing
October 2018
4 Reads

Recent Advances in Vaccines Against Leishmania Based on Patent Applications.

Recent Pat Biotechnol 2018 ;12(1):21-32

Department of Bioprocess Engineering and Biotechnology, Federal University of Parana, Curitiba. Brazil.

Background: Leishmaniasis is caused by parasites of the genus Leishmania, and represents a group of chronic diseases with an epidemiological and clinical diversity. The disease is endemic in tropical regions, being found in 98 countries, affecting around 12 million people, with an estimated increase of 1.5 million per year. Read More

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http://dx.doi.org/10.2174/1872208311666170510121126DOI Listing
July 2018
12 Reads

New Prospective for Enhancement in Bioenergy Resources Through Fungal Engineering.

Recent Pat Biotechnol 2018 ;12(1):65-76

Department of Agricultural Sciences, University of Haripur, Haripur. Pakistan.

Background: Lignin and cellulose, organic constituents of the plant or plant-based material not commonly used for feeding purpose are referred as Biomass. Patents suggest that this can be used as the best resource of renewable energy. Vesicular Arbuscular Mycorrhizae (VAM) fungi can play an effective role in biomass manufacturing through activated metabolism of the plant under dual symbiosis. Read More

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http://www.eurekaselect.com/152149/article
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http://dx.doi.org/10.2174/1872208311666170504110649DOI Listing
July 2018
4 Reads

Analysis of Recent Patenting Activities in the Field of Bioremediation of Petroleum Hydrocarbon Pollutants Present in the Environment.

Recent Pat Biotechnol 2018 ;12(1):3-20

Academy of Scientific and Innovative Research (AcSIR) and Biological Science and Technology Division, CSIR-NEIST, Jorhat-785006, Assam. India.

Background: In today's world one of the major environmental problems is the contamination of aquatic or terrestrial ecosystem due to spillage of hydrocarbon compounds produced due to various activities related to the petrochemical industry. In recent years, bioremediation has emerged as a promising technology for the restoration of these contaminated sites in an ecofriendly way.

Objective: The aim of present review literature is the compilation of patent documents on bioremediation of petroleum hydrocarbon pollutants to know technological advancements in this field. Read More

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http://dx.doi.org/10.2174/1872208311666170504111019DOI Listing
July 2018
17 Reads

Biotic Strategies for Toxic Heavy Metal Decontamination.

Recent Pat Biotechnol 2017 ;11(3):218-228

Department of Biosciences and Biotechnology, Banasthali University, Rajasthan, 304022. India.

Background: In the modern age of globalization and fast industrialization, the environmental matters are fetching more and more annoyance for human being. Patents reveal that heavy metals occur in immobilized form in sediments and as aggregates in nature. However due to the different human activities like ore mining and industrial processes, the natural biogeochemical cycles are disordered instigating amplified deposition of heavy metals in aquatic environments. Read More

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http://www.eurekaselect.com/151644/article
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http://dx.doi.org/10.2174/1872208311666170417101011DOI Listing
May 2018
11 Reads

Monoclonal Antibodies Production Against a 40KDa Band of Hydatid Cyst Fluid.

Recent Pat Biotechnol 2018 ;12(1):57-64

Cancer Prevention Research Centre, Isfahan University of Medical Sciences, Isfahan. Iran.

Background And Objectives: Hydatid cyst is the larval stage of the tapeworm Echinococcus granulosus. Hydatid cyst fluid, cyst membrane and Protoscolices, contain a complex mixture of antigens that can induce immune responses in the host. Anti-cancer properties of Protoscolices and hydatid cyst fluid has been shown. Read More

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http://dx.doi.org/10.2174/1872208311666170317151346DOI Listing
July 2018
2 Reads

Virus-Based RNA Silencing Agents and Virus-Derived Expression Vectors as Gene Therapy Vehicles.

Recent Pat Biotechnol 2017 ;11(2):141-151

Cell and Systems Biology, University of Toronto, Toronto, ON M5G 3B2. Canada.

Background: In consideration of recent developments in understanding the genomics and proteomics of viruses, the use of viral DNA / RNA sequences as well as their gene expression schemes, have found new in-roads towards the prognosis and therapy of diseases. Correspondingly, the sphere of the patenting scenario has expanded significantly.

Objectives: The current review addresses patented inventions concerning the use of virus sequences as gene silencing machineries and inventions concerning the generation and application of viral sequences as expression vectors. Read More

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http://www.eurekaselect.com/150556/article
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http://dx.doi.org/10.2174/1872208311666170301103722DOI Listing
April 2018
8 Reads

The Metabolic Syndrome and the Relevance of Nutrients for its Onset.

Recent Pat Biotechnol 2017 ;11(2):101-119

Department of Physiology and Biophysics, School of Medicine, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, OH-44106-4970. United States.

Background: Metabolic Syndrome is a pathological condition characterized by the copresence of various dysmetabolic and pathological processes including hypertension, dyslipidemia, type 2 diabetes mellitus, obesity, and cardiovascular complications. Because these conditions manifest themselves differently in a given patient, the ensuing pathophysiological state varies from patient to patient. Consequently, the order in which signs and symptoms manifest themselves can vary, making difficult to establish cause-effect relationship, and efficacious treatment and prevention options. Read More

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http://dx.doi.org/10.2174/1872208311666170227112013DOI Listing
April 2018
2 Reads

Biomolecules for Removal of Heavy Metal.

Recent Pat Biotechnol 2017 ;11(3):197-203

School of Bioscience, Institute of Management Studies, UC Campus, Ghaziabad, UP- 201015. India.

Background: Patents reveal that heavy metals are natural constituents of the earth's crust, but some heavy metals like cadmium, lead, mercury, arsenic etc. are injurious to living organisms at higher concentration. Nowadays, anthropogenic activities have altered geochemical cycles and biochemical balance of heavy metals. Read More

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http://www.eurekaselect.com/150390/article
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http://dx.doi.org/10.2174/1872208311666170223155019DOI Listing
May 2018
22 Reads

Heavy Metal Concentrations in Some Edible Vegetables: A Case Study in Uyo and Ibesikpo Asutan Local Government Areas of Akwa-Ibom State.

Recent Pat Biotechnol 2016 ;10(3):295-303

Department of Botany and Ecological Studies, University of Uyo, P.M.B. 1017, Uyo, Akwa Ibom State, Nigeria.

Background: This study assessed the level of heavy metals (Zn, Cu, Mn, Hg and Fe) accumulation in the leaves of five vegetables viz: Telfairia occidentalis, Heinsia crinata, Gnetum africanum, Talinum triangulare and Vernonia amygdalina planted in different gardens in Ibesikpo Asutan and Uyo L.G.As in Akwa Ibom State, Nigeria using standard scientific methods and reviewing latest patents. Read More

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March 2017
51 Reads

Bioconcentration of Lead in the Catfish, Heterobranchus longifilis, Valenciennes (1840) (Siluriformes: Clariidae).

Recent Pat Biotechnol 2016 ;10(3):287-294

Department of Fisheries and Aquatic Environmental Management, Faculty of Agriculture, University of Uyo, P. M. B. 1017, Uyo, Akwa Ibom State, Nigeria.

Background: Although many studies have been conducted on heavy metals in fish, there is no available information on the bioconcentration of lead in the African, air-breathing catfish, Heterobranchus longifilis (Valenciennes, 1840). Relevant patents relating to bioconcentration of lead in fish species were reviewed. Fish are useful in the evaluation of bioconcentration of lead and other metal pollutants in water. Read More

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March 2017
4 Reads