1,736 results match your criteria Reactive Arthritis Imaging

The first non-radiographic axial spondyloarthrits with COVID-19.

Immun Inflamm Dis 2021 May 12. Epub 2021 May 12.

The Rheumatology Group, South Charleston, West Virginia, USA.

Background: Case report of a 21-year-old female developing non-radiographic axialspondyloarthritis in the setting of a preceding severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. We felt this was a unique case as some cases of psoriatic arthropathy and reactive arthropathy but none, to our knowledge of non-radiographic axial spondyloarthritis.

Case Presentation: Twenty one-year-old female presented in June 2020 with inflammatory symptoms with general work-up per primary care provider being negative. Read More

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Rheumatoid meningitis: a systematic review and meta-analysis.

Eur J Neurol 2021 May 9. Epub 2021 May 9.

Department of neurology and neurosurgery, Faculty of Medicine, Hospital Clínico Universidad de Chile, Santiago, Chile.

Background: Rheumatoid meningitis (RM) is a neurological complication of rheumatoid arthritis (RA). Current evidence is based on case reports and partial reviews.

Methods: Systematic review and meta-analysis following PRISMA statement. Read More

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Pediatric Acetabular Osteomyelitis Treated With Hip Arthroscopy.

J Am Acad Orthop Surg Glob Res Rev 2021 May 4;5(5):e21.00011. Epub 2021 May 4.

From the Division of Orthopaedic Surgery, Western University, London, Ontario, Canada (Dr. Lovse); the Division of Orthopaedic Surgery, University of Ottawa, Ottawa, Ontario, Canada (Dr. Coupal); the Division of Orthopaedic Surgery, CHEO, Ottawa, Ontario, Canada (Dr. Tice, Dr. Carsen); and the Division of Infectious Diseases, CHEO, Ottawa, Ontario, Canada (Dr. Le Saux).

Osteomyelitis of the acetabulum is a rare condition accounting for only 12% of pelvic osteomyelitis cases. This report describes a previously healthy 10-year-old girl with subacute acetabular osteomyelitis and subsequent development of secondary septic arthritis of the hip. The patient presented with 3 weeks of groin pain, elevated erythrocyte sedimentation rate and C-reactive protein, synovial thickening of the hip on ultrasonography and diffuse signal uptake in the acetabulum on magnetic resonance imaging. Read More

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[Diagnostic approach and differential diagnosis of mon- and oligoarthritis].

Dtsch Med Wochenschr 2021 Apr 30;146(9):591-597. Epub 2021 Apr 30.

Reasons of mon- and oligoarthritis are heterogeneous. The diagnostic approach includes a detailed medical anamnesis, physical examination and imaging (conventional X-ray, sonography, MRI and, CT). Analysis of the synovial fluid is required in suspected septic arthritis and frequently helps in diagnosis and differential diagnosis of crystal arthropathies. Read More

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Concerted Actions by PIICP, CTXII, and TNF-α in Patients with Juvenile Idiopathic Arthritis.

Biomolecules 2021 Apr 28;11(5). Epub 2021 Apr 28.

Department of Clinical Chemistry and Laboratory Diagnostics, Faculty of Pharmaceutical Sciences in Sosnowiec, Medical University of Silesia, ul. Jedności 8, 41-200 Sosnowiec, Poland.

Joint destruction in juvenile idiopathic arthritis (JIA), initiated in the early, preclinical stage of the disease, is diagnosed on the basis of clinical evaluation and radiographic imaging. The determination of circulating cartilage-matrix turnover markers can facilitate the diagnosis and application of better and earlier treatment strategies for JIA. We have shown that 96 JIA patients have elevated levels of procollagen II C-terminal propeptide (PIICP), reflecting the extent of joint cartilage biosynthesis, and C-telopeptide of type II collagen (CTXII), a biomarker of the resorption of this tissue. Read More

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Axial and peripheral spondyloarthritis triggered by sars-cov-2 infection: a report of two cases.

Reumatismo 2021 Apr 19;73(1):59-63. Epub 2021 Apr 19.

Division of Rheumatology, Department of Internal Medicine, American University of Beirut Medical Center, Beirut.

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection can show musculoskeletal symptoms such as peripheral arthritis. In rare cases, peripheral arthritis can develop after the resolution of SARS-CoV-2. We present two cases of spondyloarthritis induced by SARS-CoV-2; one case with axial and peripheral spondyloarthritis and the other with peripheral spondyloarthritis. Read More

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Rapidly destructive coxopathy due to dialysis amyloidosis: a case report.

Mod Rheumatol Case Rep 2021 Apr 15:1-5. Epub 2021 Apr 15.

Department of Orthopaedic Surgery and Rheumatology, Toho University Sakura Medical Center, Chiba, Japan.

Rapidly destructive coxopathy (RDC) is a disease that is sometimes seen in geriatric patients. A total hip arthroplasty (THA) is mostly chosen to treat the RDC, but few cases are known that received THAs due to RDC associated with dialysis amyloidosis. We report a case of RDC due to dialysis amyloidosis with special references to its pathophysiology. Read More

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Severe erosive lesion of the glenoid in gouty shoulder arthritis: a case report and review of the literature.

BMC Musculoskelet Disord 2021 Apr 12;22(1):343. Epub 2021 Apr 12.

Department of Orthopedics, Inner Mongolia People's Hospital, No. 20 Zhao Wu Da Street, Inner Mongolia Autonomous Region, 010017, Hohhot, China.

Background: Gout is a metabolic disease characterized by recurrent episodes of acute arthritis. Gout has been reported in many locations but is rarely localized in the shoulder joint. We describe a rare case of gouty arthritis involving bilateral shoulder joints and leading to severe destructive changes in the right shoulder glenoid. Read More

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Children with Primary Septic Arthritis Have a Markedly Lower Risk of Adverse Outcomes Than Those with Contiguous Osteomyelitis.

J Bone Joint Surg Am 2021 Apr 12. Epub 2021 Apr 12.

Children's Health System of Texas, Dallas, Texas.

Background: It is widely believed that septic arthritis poses a risk of joint destruction and long-term adverse outcomes for children if not treated emergently. In the present study, children who had primary confirmed septic arthritis were compared with those who had septic arthritis and adjacent osteomyelitis to evaluate differences that affect the relative risk of adverse outcomes.

Methods: Children who underwent multidisciplinary treatment for septic arthritis with or without contiguous osteomyelitis between 2009 and 2019 were retrospectively studied. Read More

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Wegener's granulomatosis with orbital involvement: case report and literature review.

Rom J Ophthalmol 2021 Jan-Mar;65(1):93-97

Emergency Eye Hospital, Bucharest, Romania.

To describe the chronology and the extent of orbital involvement in a case of granulomatosis with polyangiitis. Descriptive case report and literature review. A 45-year-old patient, formerly diagnosed with granulomatosis with polyangiitis due to otorhinolaryngologic manifestations, pulmonary lesions, renal impairment, left knee arthritis and high blood levels of antineutrophil cytoplasmic antibodies, addressed the Ophthalmology Department in November 2020, having the following complaints: left eye mild retro-orbital discomfort, proptosis and epiphora. Read More

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[Pericarditis in contemporary therapeutic clinic: nosological spectrum, approaches to diagnosis and treatment].

Ter Arkh 2020 Dec 15;92(12):10-18. Epub 2020 Dec 15.

Sechenov First Moscow State Medical University (Sechenov University).

Aim: To analyze the register of pericarditis in a therapeutic clinic, to evaluate their nosological spectrum, to optimize approaches to diagnosis and treatment.

Materials And Methods: For the period 20072018, the register includes 76 patients with the diagnosis of pericarditis (average age 53.115. Read More

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December 2020

Alterations of Extracellular Matrix Components in the Course of Juvenile Idiopathic Arthritis.

Metabolites 2021 Feb 25;11(3). Epub 2021 Feb 25.

Department of Clinical Chemistry and Laboratory Diagnostics, Faculty of Pharmaceutical Sciences in Sosnowiec, Medical University of Silesia, ul. Jedności 8, 41-200 Sosnowiec, Poland.

Juvenile idiopathic arthritis (JIA) is the most common group of chronic connective tissue diseases in children that is accompanied by joint structure and function disorders. Inflammation underlying the pathogenic changes in JIA, caused by hypersecretion of proinflammatory cytokines, leads to the destruction of articular cartilage. The degradation which progresses with the duration of JIA is not compensated by the extent of repair processes. Read More

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February 2021

Reactive arthritis after COVID-19.

BMJ Case Rep 2021 Mar 2;14(3). Epub 2021 Mar 2.

Intensive Care, Aarhus Universitetshospital, Aarhus, Denmark.

A previously healthy 53-year-old man was hospitalised for 12 days due to COVID-19 with shortness of breath. A few days after discharge from hospital, the patient developed fever and severe pain in several joints in the lower extremities. The pain was so severe that the patient was unable to stand on his feet. Read More

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Isolated brachial artery aneurysm: a rare presentation of paediatric Behçet's disease.

Ann R Coll Surg Engl 2021 Mar;103(3):e94-e97

Department of General Surgery, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

Behçet's disease is a rare disease characterised by recurrent oral ulcers, with systemic manifestations including genital ulcers, ocular disease, skin lesions, gastrointestinal disease, neurologic disease, vascular disease and arthritis. Most clinical manifestations of Behçet's disease are believed to be due to vasculitis. The heterogeneous clinical spectrum is influenced by sex, ethnicity and country of residence. Read More

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Semi-quantitative analysis of F fluorodeoxyglucose uptake in the assessment of disease activity and therapeutic response in rheumatoid arthritis: An institutional experience.

World J Nucl Med 2020 Oct-Dec;19(4):347-352. Epub 2020 Jun 27.

Department of Internal Medicine, Diana Princess of Wales Hospital, Grimsby, United Kingdom.

F fluorodeoxyglucose (F-FDG) positron emission tomography (PET) can be used to image synovial inflammation in patients with rheumatoid arthritis (RA). Recently, clinical application of novel therapies for RA, such as tumor necrosis factor-α (TNF-α) inhibitor and anti-interleukin-6 receptor antibody, has been introduced. The radiological assessment of disease activity changes of patients who underwent these therapies will help the clinicians to obtain more information about the patients and to decide drug withdrawal or change of medication. Read More

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Tumours and tumour-like lesions of joints: Differential diagnoses in a paediatric population compared to adults.

Br J Radiol 2021 Apr 22;94(1120):20201389. Epub 2021 Feb 22.

Department of Radiology, Royal National Orthopaedic Hospital, Stanmore, UK.

Objective: To determine the differential diagnosis of intra-articular tumours and tumour-like lesions in a paediatric population compared to adults.

Methods: Retrospective review of children up to the age of 18 years with suspected intra-articular tumours and tumour-like lesions referred to a specialist musculoskeletal oncology service from January 2019 to August 2020. Data recorded included patient age and gender, lesion location and morphology (based on the classification system of Adams et al. Read More

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Pain for Greater Than 4 Days Is Highly Predictive of Concomitant Osteomyelitis in Children With Septic Arthritis.

J Pediatr Orthop 2021 Apr;41(4):255-259

Children's Orthopedic Center, Children's Hospital Los Angeles.

Background: There is no evidence-based consensus on the risk factors for concomitant osteomyelitis and septic arthritis. The purpose of this study was to investigate clinical parameters predictive of concomitant osteomyelitis in children with septic arthritis.

Methods: A retrospective review was conducted on patients with septic arthritis with magnetic resonance imaging (MRI) between January 2004 and October 2016 at a tertiary care pediatric hospital. Read More

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Capsaicin-Sensitive Peptidergic Sensory Nerves Are Anti-Inflammatory Gatekeepers in the Hyperacute Phase of a Mouse Rheumatoid Arthritis Model.

Int J Mol Sci 2021 Feb 8;22(4). Epub 2021 Feb 8.

János Szentágothai Research Centre, Molecular Pharmacology Research Team, University of Pécs, H-7624 Pécs, Hungary.

Capsaicin-sensitive peptidergic sensory nerves play complex, mainly protective regulatory roles in the inflammatory cascade of the joints via neuropeptide mediators, but the mechanisms of the hyperacute arthritis phase has not been investigated. Therefore, we studied the involvement of these afferents in the early, "black box" period of a rheumatoid arthritis (RA) mouse model. Capsaicin-sensitive fibres were defunctionalized by pretreatment with the ultrapotent capsaicin analog resiniferatoxin and arthritis was induced by K/BxN arthritogenic serum. Read More

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February 2021

Tenosynovitis has a high sensitivity for early ACPA-positive and ACPA-negative RA: a large cross-sectional MRI study.

Ann Rheum Dis 2021 Feb 5. Epub 2021 Feb 5.

Rheumatology, Leiden University Medical Center, Leiden, Zuid-Holland, The Netherlands.

Objectives: Clinically evident tenosynovitis can be seen in established rheumatoid arthritis (RA). Imaging research has recently shown that tenosynovitis at small joints occurs in early RA, contributes to typical RA symptoms (including joint swelling) and is infrequent in healthy controls. Imaging-detectable tenosynovitis is often not recognisable at joint examination, hence its prevalence can therefore be underestimated. Read More

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February 2021

Modern Day Scurvy in Pediatric Orthopaedics: A Forgotten Illness.

J Pediatr Orthop 2021 Mar;41(3):e279-e284

Penn State College of Medicine.

Introduction: Scurvy, or vitamin C deficiency, is rare. The goal of this study is to highlight the common risk factors and identify the orthopaedic presentation of scurvy in children.

Methods: A retrospective chart and radiograph review was performed of all patients consulted to the pediatric orthopaedic service from 2010 to 2019 who ultimately had the diagnosis of scurvy confirmed by an abnormally low serum vitamin C level. Read More

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Filgotinib versus placebo or adalimumab in patients with rheumatoid arthritis and inadequate response to methotrexate: a phase III randomised clinical trial.

Ann Rheum Dis 2021 Jan 27. Epub 2021 Jan 27.

Griffith University, Brisbane, Queensland, Australia.

Objective: To evaluate the efficacy and safety of the Janus kinase-1-preferential inhibitor filgotinib versus placebo or tumour necrosis factor-α inhibitor therapy in patients with active rheumatoid arthritis (RA) despite ongoing treatment with methotrexate (MTX).

Methods: This 52-week, multicentre, double-blind, placebo-controlled and active-controlled phase III trial evaluated once-daily oral filgotinib in patients with RA randomised 3:3:2:3 to filgotinib 200 mg (FIL200) or filgotinib 100 mg (FIL100), subcutaneous adalimumab 40 mg biweekly, or placebo (through week 24), all with stable weekly background MTX. The primary endpoint was the proportion of patients achieving 20% improvement in American College of Rheumatology criteria (ACR20) at week 12. Read More

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January 2021

[Predictive value of anti-mutated citrullinated vimentin antibody on one-year radiographic progression in patients with rheumatoid arthritis].

Zhonghua Nei Ke Za Zhi 2021 Feb;60(2):128-133

Department of Rheumatology and Immunology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510120, China.

To investigate the value of baseline anti-mutated citrullinated vimentin (MCV) antibody for predicting one-year radiographic progression in patients with rheumatoid arthritis (RA). Consecutive RA patients were recruited from November 2014 to July 2018 at Department of Rheumatology, Sun Yat-sen Memorial Hospital, Clinical data were collected including disease activity score in 28 joints with four variables including C-reactive protein (CRP).Serum anti-MCV antibody at baseline was detected by enzyme-linked immunosorbent assay. Read More

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February 2021

HSP60 Regulates Monosodium Urate Crystal-Induced Inflammation by Activating the TLR4-NF-B-MyD88 Signaling Pathway and Disrupting Mitochondrial Function.

Oxid Med Cell Longev 2020 31;2020:8706898. Epub 2020 Dec 31.

Institute of Rheumatology and Immunology, The Affiliated Hospital of North Sichuan Medical College, 63# Wenhua Road, Nanchong, 637000 Sichuan, Nanchong, China.

Acute gout is an inflammatory response induced by monosodium urate (MSU) crystals. HSP60 is a highly conserved stress protein that acts as a cellular "danger" signal for immune reactions. In this study, we aimed to investigate the role and molecular mechanism of HSP60 in gout. Read More

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December 2020

The Relationship Between Serum Angiogenic Factor Levels and Disease Activity in Rheumatoid Arthritis.

Arch Rheumatol 2020 Sep 8;35(3):416-425. Epub 2020 Jan 8.

Department of Biochemistry, Manisa Celal Bayar University Faculty of Medicine, Manisa, Turkey.

Objectives: This study aims to evaluate the relationship between serum angiogenic factor levels and disease activity in patients with rheumatoid arthritis (RA) using both clinical and dynamic wrist magnetic resonance imaging (MRI) data.

Patients And Methods: Simultaneous serum angiogenesis markers [vascular endothelial growth factor (VEGF), angiopoietin-1 (ANG1), ANG2, and tyrosine-protein kinase receptor for angiopoietin (Tie-2)] were studied in 40 patients with RA (13 males, 27 females; mean age 51.1±10. Read More

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September 2020


Acta Clin Croat 2020 Jun;59(2):368-372

1University Hospital of Foča, Department of Radiology, University of East Sarajevo, Foča, Republika Srpska, Bosnia and Herzegovina; 2Srebrnjak Children's Hospital, Zagreb, Croatia; 3Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia.

Acute osteomyelitis is pyogenic infection of the bone and bone marrow. We report a case of successful diagnosis and treatment in a 12-year-old boy with right shoulder joint osteoarthritis. On admission, he was febrile (39. Read More

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Chlamydia-infected Macrophages mediate Interleukin-23 and Tumor Necrosis Factor-driven Reactive Arthritis in SKG Mice.

Arthritis Rheumatol 2021 Jan 16. Epub 2021 Jan 16.

Univ. Grenoble Alpes, GREPI TIMC-IMAG, UMR 5525, 38000, Grenoble, France.

Objective: ZAP-70 BALB/c (SKG) mice develop reactive arthritis (ReA) after Chlamydia muridarum (Cmu) infection. Since intracellular pathogens enhance their replicative fitness in stressed host cells, we examined how myeloid cells taking up Cmu drive arthritis.

Methods: Female SKG, Il17a-deficient SKG and BALB/c mice were genitally infected with Cmu or Cmu Luciferase. Read More

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January 2021

The Utility of 18F-FDG PET/CT in Patients With Clinical Suspicion of Polymyalgia Rheumatica and Giant Cell Arteritis: A Prospective, Observational, and Cross-sectional Study.

ACR Open Rheumatol 2020 Aug 22;2(8):478-490. Epub 2020 Jul 22.

University of Southern Denmark, Odense, Denmark.

Objective: To define the proportions of agreement between fluorine-18-fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT), clinical diagnosis, and temporal artery biopsy (TAB) in patients with polymyalgia rheumatica (PMR) and giant cell arteritis (GCA). Furthermore, the association of 18F-FDG PET/CT uptake patterns and clinical presentation of newly diagnosed PMR and GCA was investigated.

Methods: Eighty patients newly suspected of having PMR, GCA, or concomitant PMR and GCA were included and followed for 40 weeks. Read More

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Long-term application of hydroxychloroquine could not prevent the infection of COVID-19.

J Infect Dev Ctries 2020 12 31;14(12):1368-1373. Epub 2020 Dec 31.

Department of Infectious Diseases and Liver Diseases, Ningbo Medical Center Lihuili Hospital, Affiliated Hospital of Ningbo University, China.

Introduction: Current pandemic of the coronavirus induced disease 2019 (COVID-19) presents an urgent issue to the world due to lack of vaccine and medication. Hydroxychloroquine (HCQ) has generated a lot of controversies whether it is effective in prevention and treatment of COVID-19. Current report presents a 63-year-old woman who has taken HCQ for many years but still infected by COVID-19. Read More

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December 2020

Unilateral knee effusion in an elderly patient: an unusual presentation of rheumatoid arthritis.

J Prim Health Care 2020 12;12(4):391-394

University of Colorado School of Medicine, Department of Family Medicine & Orthopedics, Division of Sports Medicine, AF Williams Clinic, Denver, Colorado, USA.

Unilateral atraumatic knee effusion is a relatively common presenting complaint among geriatric patients in primary care and musculoskeletal speciality clinics. Gout, pseudogout, degenerative joint diseases and reactive arthritis are the most common causes of the atraumatic knee effusions. Rheumatoid arthritis very rarely presents as arthritis of one or two large joints. Read More

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December 2020

Treatment of Psoas abscess related coxarthrosıs due to salmonella infection in a patient wıth chronic renal failure. A case report.

Ann Ital Chir 2020 Dec 3;9. Epub 2020 Dec 3.

Introduction: The most common microorganisms isolated from septic arthritis are staphylococcus aureus and streptoccocci. Septic arthritis due to Salmonella spp. is extremely rare. Read More

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December 2020