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Z Geburtshilfe Neonatol 2018 Dec 10;222(6):262-265. Epub 2018 Dec 10.

Obstetrics and Gynecology, Necmettin Erbakan Universitesi Meram Tip Fakultesi, Konya, Turkey.

A foetal sublingual cystic lesion was diagnosed by routine prenatal ultrasonography at 27 weeks of gestation. Foetal growth and amniotic fluid volume were normal. An ex utero intrapartum treatment (EXIT) procedure was performed, and the cyst was aspirated to allow breathing during planned Caesarean section. Read More

J Cancer Res Ther 2018 Oct-Dec;14(6):1418-1421

Department of Oral Medicine and Radiology, Kamineni Institute of Dental Sciences, Hyderabad, Telangana, India.

Malignant tumors of the salivary gland are rare, clinically diverse group of neoplasms, among which mucoepidermoid carcinomas (MECs) are reported to be most frequently occurring epithelial carcinomas. MEC at times misleads the clinician because of its atypical location and innocent appearance. Here, we report a case of low-grade MEC in a 70-year-old female patient in the floor of the mouth mimicking as ranula clinically. Read More

Oral Radiol 2018 Sep 4;34(3):224-228. Epub 2017 Sep 4.

Department of Radiology, The Nippon Dental University Niigata Hospital, 1-8 Hamaura-cho, Chuo-ku, Niigata, Niigata, 951-8580, Japan.

Objectives: The aim of this study was to investigate the usefulness of diffusion-weighted magnetic resonance imaging (DWI) in oral and maxillofacial lesions, especially the utility of apparent diffusion coefficient (ADC) maps for differential diagnosis of these lesions.

Methods: Fifty-seven patients who underwent magnetic resonance imaging for diagnosis of oral and maxillofacial lesions were included in this prospective study. DWI was performed on a 1. Read More

Oral Surg Oral Med Oral Pathol Oral Radiol 2018 Sep 9. Epub 2018 Sep 9.

Division of Oral and Maxillofacial Radiology, Kyushu Dental University, Kitakyushu, Japan. Electronic address:

Objective: The aim of this study was to evaluate the characteristics of diffusion-weighted imaging (DWI) and apparent diffusion coefficient (ADC) values of ranulas. In addition, to elucidate DWI findings and ADC values of other representative masses in and around the floor of the mouth.

Study Design: DWI findings and ADC values in 35 patients with ranulas and 33 patients with other masses were retrospectively reviewed with a central focus on cystic masses or lesions that may have cyst-like components in and around the floor of the mouth based on the diagnosis of each respective disease. Read More

J Family Community Med 2018 Sep-Dec;25(3):217-219

Department ENT, Imam Abdulrahman Bin Faisal Univeristy, College of Medicine, Dammam, Saudi Arabia.

Plunging ranula (PR) is a cystic mass presenting on the lateral side of the neck with or without a history of the usual presentation of an intraoral lesion. "PR" is recognized as an uncommon lesion that has been found predominantly in the third decade of life mostly in males. However, the exact prevalence of "PR" is not yet known. Read More

J Clin Pediatr Dent 2018 7;42(6):454-457. Epub 2018 Aug 7.

Ranula consists of a pathological process induced by ductal disruption of the minor salivary glands followed by extravasation of mucous material surrounding adjacent structures. A swelling causing breathing and feeding problems associated with tongue displacement is frequently observed. It is a disease that generally involves the younger age group. Read More

Am J Otolaryngol 2018 Sep - Oct;39(5):497-500. Epub 2018 May 26.

Department of Otolaryngology, Massachusetts Eye and Ear, Boston, MA 02114, United States; Division of Head and Neck Surgery, Massachusetts Eye and Ear, Boston, MA, 02114, United States. Electronic address:

Objective: A plunging ranula is a pseudocystic collection of mucin extravasated from the sublingual gland into the floor of mouth and through the mylohyoid muscle into the neck. While the lining of a ranula is non-secreting and resection of the sublingual gland is adequate for simple sublingual mucoceles, many surgeons attempt to address plunging ranulas with extensive transoral and transcervical dissections. We review our experience managing plunging ranulas with intraoral sublingual gland excision and ranula drainage alone. Read More

J Oral Maxillofac Surg 2018 Jun 2. Epub 2018 Jun 2.

Professor and Chief, Department of Oral and Maxillofacial Surgery, Guanghua School of Stomatology, Guangdong Provincial Key Laboratory of Stomatology, Sun Yat-sen University, Guangzhou, China. Electronic address:

Purpose: Keratoconjunctivitis sicca (KCS) is a relatively common disease that results in discomfort, tear film instability, visual impairment, and ocular surface damage. Artificial tear substitutes may be suitable for the treatment of mild KCS, but no effective treatment currently exists for severe KCS. Therefore, this study evaluated the effectiveness of autologous microvascular submandibular gland transplantation in the treatment of severe KCS. Read More

Case Rep Dent 2018 24;2018:3048429. Epub 2018 Apr 24.

Unit of Orthodontics and Paediatric Dentistry, Section of Dentistry, Department of Clinical, Surgical, Diagnostic and Paediatric Sciences, University of Pavia, Pavia, Italy.

Mucocele (also known as ranula or salivary gland mucous cyst) of the newborn is a lesion present on the intraoral cavity, with the potential to interfere with respiration and feeding. In the present report, a case of mucocele in a 4-month female patient has been described. As conventional surgery can be followed by several complications such as intraoperative bleeding, difficulties in wound healing, and maintenance of sterility during surgery, in the present case, the use of diode laser has been planned. Read More

Int J Pediatr Otorhinolaryngol 2018 10 9;113:303-304. Epub 2018 May 9.

Knox College, Galesburg, IL, USA.

World J Surg 2018 May 10. Epub 2018 May 10.

Department of Surgery, University of Auckland, Auckland, New Zealand.

J Clin Exp Dent 2018 Jan 1;10(1):e92-e95. Epub 2018 Jan 1.

Professor, Department of Oral Pathology and Microbiology, Tamilnadu government Dental College and Hospital, Chennai, India.

The term Ranula is a Latin word meaning frog. It refers to a bluish translucent cystic lesion in the floor of the mouth resembling the underbelly of a frog. Ranulas can be true cysts occurring due to ductal obstruction of the sublingual gland or a minor salivary gland or a pseudocyst as a result of ductal injury leading to extravasation and accumulation of saliva in the surrounding tissues. Read More

Neuroimaging Clin N Am 2018 May 7;28(2):209-226. Epub 2018 Mar 7.

Department of Medical Imaging, University of Arizona College of Medicine, 1501 North Campbell Avenue, Tucson, AZ 85724, USA.

Salivary gland diseases in children are uncommon, and the relative incidence of pathologies is different than in adults. This article presents a comprehensive review of congenital and acquired disorders that affect the major salivary glands in the pediatric population, highlighting the imaging findings that are important in defining the appropriate diagnosis or narrowing of the differential diagnosis. Read More

Neuroimaging Clin N Am 2018 May;28(2):159-169

Department of Radiology, University of Chicago, Pritzker School of Medicine, 5841 South Maryland Avenue, Chicago, IL 60637, USA. Electronic address:

This article reviews the multimodality diagnostic imaging features of benign neoplastic and nonneoplastic tumors associated with the major salivary glands. Examples of neoplastic conditions that are depicted and discussed include pleomorphic adenoma, Warthin tumor, oncocytoma, peripheral nerve sheath tumors, lipoma, and hemangiomas or hemangioendotheliomas. Examples of nonneoplastic conditions that are depicted and discussed include ranulas, benign lymphoepithelial lesions, Kimura disease, and vascular malformations. Read More

J Stomatol Oral Maxillofac Surg 2018 Jun 1;119(3):172-176. Epub 2018 Mar 1.

Department of Oral and Maxillofacial Surgery, Lille Teaching Hospital, Roger Salengro Hospital, Lille Teaching Hospital, 59000 Lille, France; Inserm U 1008, Controlled Drug Delivery Systems and Biomaterials, Roger Salengro Hospital, Lille Teaching Hospital, 59000 Lille, France. Electronic address:

Introduction: The aim of this study was to analyze the clinical features and treatment outcomes in order to determine the optimal management of ranulas in our Oral and Maxillofacial Surgery department with long-term results.

Patients And Methods: A retrospective study was performed to evaluate patients with a final diagnosis of a simple or plunging ranula at Lille Teaching Hospital from May 2000 to January 2017. Clinical data on ranulas that were reviewed included gender, age, symptoms, location of the lesion, surgical procedures, complications, recurrence and follow-up. Read More

Saudi J Anaesth 2018 Jan-Mar;12(1):163-165

Department of Anaesthesia and Critical Care, Lady Hardinge Medical College, New Delhi, India.

Clin Case Rep 2018 01 29;6(1):109-114. Epub 2017 Nov 29.

Oral and Maxillofacial Surgery Unit General Hospital Lagos Island Lagos Nigeria.

Plunging ranulas are rare; report of this condition is particularly limited in our environment. We present case series in children; with all cases having both oral and cervical components. It is important to note this type of presentation of plunging ranula and their appropriate management. Read More

Br J Oral Maxillofac Surg 2018 02 12;56(2):129-133. Epub 2018 Jan 12.

Department of Oral Surgery, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Key Laboratory of Stomatology, National Clinical Research Center of Stomatology, Shanghai 200011, China. Electronic address:

The two-incision fistula technique for the treatment of oral ranulas has recently been introduced to clinical practice. We reviewed 52 patients who had recurrences after this treatment, and explored the possible causes and underlying mechanisms. A total of 13/53 ranulas had recurred, so we repeated the operation, and one patient had the ranula and the sublingual gland resected. Read More

World J Surg 2018 04;42(4):1210-1211

Department of General Surgery, College of Medicine, University of Jos & Jos University Teaching Hospital, Jos, Plateau State, Nigeria.

ANZ J Surg 2018 Oct 21;88(10):1043-1046. Epub 2017 Dec 21.

Department of Otolaryngology and Head and Neck Surgery, Logan Hospital, Logan City, Queensland, Australia.

Background: Plunging ranulas are rare mucous extravasation pseudocysts that arise in the floor of the mouth and pass into the submandibular space of the neck. The aim of this study was to investigate the diagnosis, surgical management and outcomes of patients with a plunging ranula at our institution in South East Queensland over a 10-year period.

Methods: A retrospective analysis of adult patients diagnosed with and treated for plunging ranula between 2006 and 2016 at Logan Hospital was conducted. Read More

Dentomaxillofac Radiol 2018 May 10;47(4):20170331. Epub 2018 Jan 10.

1 Department of Oral Pathology, Radiology and Medicine,College of Dentistry, The University of Iowa , Iowa City, IA , USA.

Mucoepidermoid carcinoma (MEC) is the most common salivary gland malignancy. The submandibular gland is rarely involved, about less than 10% of all other major salivary glands. We report a case of a 49-year-old female who presented with a mass on the left side of the floor of the mouth. Read More

J Clin Diagn Res 2017 Sep 1;11(9):ZE06-ZE09. Epub 2017 Sep 1.

Senior Lecturer, Department of Oral and Maxillofacial Surgery, Saveetha Dental College, Chennai, Tamil Nadu, India.

Introduction: Ranula is mucous extravasation cyst that occurs in the floor of the mouth. There are various methods of management of paediatric oral ranula each of which has their own advantage and disadvantage.

Aim: The aim of this paper was to systematically review the available literature on the management of paediatric oral ranula. Read More

ORL J Otorhinolaryngol Relat Spec 2017 29;79(6):306-313. Epub 2017 Nov 29.

Department of Otorhinolaryngology - Head and Neck Surgery, University of Pennsylvania, Philadelphia, PA, USA.

Background/aims: Plunging ranulas are oral mucoceles that often cannot be visualized directly and thus can be challenging to diagnose and differentiate from other neck lesions. Surgery is the preferred treatment option, but the optimal approach requires careful consideration.

Methods: We report the case of a plunging ranula presenting as an isolated neck mass in a 33-year-old patient. Read More

J Paediatr Child Health 2017 Nov;53(11):1086-1090

Paediatric Surgery, Royal Children's Hospital Melbourne, Melbourne, Victoria, Australia.

Midline cervical swellings are a heterogeneous group of conditions in children. Careful clinical examination will allow a diagnosis to be made in many instances and appropriate investigations to be performed before referral to surgical services. The approach to clinical examination, investigation and management of the most common conditions is described. Read More

J Maxillofac Oral Surg 2017 Dec 16;16(4):491-496. Epub 2017 Mar 16.

Department of Oral and Maxillofacial Surgery, AJ Institute of Dental Science and Hospital, Mangalore, Karnataka 575004 India.

Background: This study was undertaken to compare micromarsupialization and modified micromarsupialization for the management of mucoceles.

Materials And Methods: A prospective randomized clinical study was done on thirty patients having mucocele on lower lip. In Group A ( = 15), micromarsupialization and in Group B ( = 15), modified micromarsupialization technique was used. Read More

J Craniofac Surg 2018 Mar;29(2):469-470

Unit of Otorhinolaryngology, Department of Biotechnology and Life Sciences (DBSV), University of Insubria, Azienda Ospedaliero-Universitaria Ospedale di Circolo e Fondazione Macchi, Varese, Italy.

Cystic lesions involving the tongue base are rare, generally presenting in pediatric patients, and they may encompass different pathologies such as ranula, lingual ectopic thyroid, thyroglossal duct cyst (TDC), dysontogenetic cysts, benign, and malignant tumors.This paper describes the case of a 19-year-old girl with phonation impairment and mild dysphagia due to limited tongue protrusion and movements. Radiologic examinations revealed a bulky cystic lesion at the base of tongue with displacement of extrinsic lingual muscles. Read More

J Indian Assoc Pediatr Surg 2017 Oct-Dec;22(4):251-253

Department of Paediatric Surgery, King Georges Medical University, Lucknow, Uttar Pradesh, India.

Congenital ranula is rare. We report a large, symptomatic, congenital plunging ranula associated with a salivary gland cyst in the neck. To the best of our knowledge, this is the first such reported case. Read More

Int J Pediatr Otorhinolaryngol 2017 Oct 19;101:11-19. Epub 2017 Jul 19.

Department of Otolaryngology/Head and Neck Surgery, Oregon Health and Science University, 3181 SW Sam Jackson Park Road, PV01, Portland, OR 97239, United States. Electronic address:

Context: Primary Sjögren syndrome is uncommon in children, and the standard clinical criteria used in diagnosis of adult Sjögren syndrome will miss many children with the disease. Floor of mouth ranulas have not been described in Sjögren syndrome.

Objective: This study aims to describe a novel presentation of juvenile primary Sjögren syndrome, and to present a comprehensive systematic review of the literature regarding the presentation and diagnosis of Sjögren syndrome in children. Read More

J Clin Pediatr Dent 2017;41(5):381-383

A ranula is a lesion that arises from mucin spillage from the sublingual or submandibular gland ducts, beneath the mucosa of the oral floor. A plunging or cervical ranula dissects the mylohyoid muscle and appears as a submandibular swelling. Rarely, a plunging ranula is encountered without its oral counterpart. Read More

Histopathology 2018 Jan 3;72(2):330-338. Epub 2017 Nov 3.

Oral Diagnosis Department, Semiology and Oral Pathology Areas, Piracicaba Dental School, University of Campinas (UNICAMP), São Paulo, Brazil.

Aim: The aim of this study was to analyse allelic loss of the phosphatase and tensin homologue deleted on chromosome 10 (PTEN) gene and its protein immuno-expression in dysplastic oral lesions and oral squamous cell carcinomas (OSCCs).

Methods And Results: Samples were collected from 153 patients [20 ranulas used as a control (C); 30 leucoplakias with mild dysplasia (MD); 30 leucoplakias with moderate to severe dysplasia (MSD); 73 oral squamous cell carcinoma (OSCC)]. PTEN protein expression was investigated using immunohistochemistry, and PTEN allelic loss was analysed by fluorescence in-situ hybridisation (FISH). Read More

Acta Otolaryngol 2017 Dec 28;137(12):1271-1274. Epub 2017 Jul 28.

a Department of Otorhinolaryngology - Head and Neck Surgery , Helsinki University Hospital and University of Helsinki , Helsinki , Finland.

Objectives: To review our clinical experience and characteristics of Finnish patients with plunging ranula and compare our results with reports from other populations.

Design: A retrospective study from the electronic hospital records between 2005 and 2016.

Setting: The Department of Otorhinolaryngology and Head and Neck Surgery of Helsinki University Hospital, Finland. Read More

World J Surg 2018 04;42(4):1208-1209

Division of Mucosal and Salivary Biology, King's College London Dental Institute at Guy's, King's College and St Thomas' Hospitals, London, England.

Ann Maxillofac Surg 2017 Jan-Jun;7(1):155-158

Department of Oral and Maxillofacial Surgery, Institute of Dental Sciences, Siksha 'O' Anusandhan University, Bhubaneswar, Odisha, India.

An elderly female patient presented to surgical outpatient clinic with complaint of gradual onset of painless submental and sublingual midline swellings for 6 months of duration. The swellings were noncompressible, nontranslucent, nonpulsatile, and nontender on palpation. Clinical diagnosis was plunging ranula or dermoid cysts. Read More

J Appl Oral Sci 2017 May-Jun;25(3):341-345

Universidade Federal do Rio Grande do Sul, Faculdade de Odontologia; Hospital de Clínicas de Porto Alegre, Unidade de Cirurgia Buco-maxilo-facial, Porto Alegre, RS, Brasil.

Lesions in the floor of the mouth can be a challenging diagnosis due to the variety of pathological conditions that might be found in this area. Within a broad range of lesions, attention has to be addressed to those that require specific management, such as a dermoid cyst (DC) and a ranula. Especially in pediatric patients, in whom the failure of diagnosis can postpone the correct treatment and cause sequelae later in life. Read More

AJNR Am J Neuroradiol 2017 Sep 29;38(9):1794-1798. Epub 2017 Jun 29.

From the Department of Radiology and Research Institute of Radiology (K.H.R., J.H.L., J.Y.L., S.R.C., M.S.C., H.W.K., Y.J.C., J.H.B.), University of Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea.

Background And Purpose: Surgical excision of an affected sublingual gland for treatment of a ranula can carry a potential of a nerve damage or postoperative complications. However, there have been little studies about effective minimally invasive therapeutic method, yet. Our aim was to evaluate the efficacy and safety of ethanol ablation of ranulas and the clinicoradiologic factors that can predict outcome. Read More

J Clin Pediatr Dent 2017;41(4):305-307

Ranulas pose a challenging situation, both clinically and surgically, because of their location on the floor of the mouth, an area that exhibits tightly-netted vital structures. Several treatments have been proposed, including excision with or without removal of the sublingual gland, marsupialization with or without cauterization of the roof of the lesion, drainage of the lesion, and micro-marsupialization. It has been suggested that a modified micro-marsupialization technique can establish drainage of saliva and formation of new permanent epithelized tracts along the path of sutures, thereby reducing the recurrence. Read More

J Vet Dent 2017 Sep 21;34(3):148-154. Epub 2017 Jun 21.

1 Metropolitan Veterinary Associates, Valley Forge, PA, USA.

The present study compares a knotless, barbed, absorbable suture material against a conventional monofilament absorbable suture material in oral mucosal wound closure. The parameters measured include time of closure and differences in healing at 2 and 4 weeks postoperatively. A prospective study comparing a knotless, barbed suture system with conventional absorbable sutures was undertaken in 19 cats. Read More

Am J Otolaryngol 2017 Nov - Dec;38(6):724-725. Epub 2016 Nov 23.

Department of Pathology, Louisiana State University Health Science Center, Shreveport, LA 71130, USA.

Oral foregut duplication cysts are extremely rare lesions with approximately 57 cases reported. They are congenital cysts, located in the anterior or ventral tongue, and occur predominantly in males. They are lined by one or more types of epithelia which is limited to gastric, intestinal or respiratory epithelium. Read More

Acta Otorhinolaryngol Ital 2017 Apr;37(2):160-167

Department of Otolaryngology and Head and Neck Surgery, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.

Recent technological improvements in head and neck field have changed diagnostic and therapeutic strategies for salivary disorders. Diagnosis is now based on colour Doppler ultrasonography (US), magnetic resonance (MR) sialography and cone beam 3D computed tomography (CT), and extra- and intracorporeal lithotripsy, interventional sialendscopy and sialendoscopy-assisted surgery are used as minimally invasive, conservative procedures for functional preservation of the affected gland. We evaluated the results of our long-term experience in the management of paediatric obstructive salivary disorders. Read More

Acta Otorhinolaryngol Ital 2017 Apr;37(2):142-147

Oral and Maxillofacial Surgery Department Barzilai Medical Center, Ashkelon, Israel. Affiliated to the Faculty of Medicine, Ben Gurion University of the Negev, Beer Sheva, Israel.

The morbidity following traditional surgery of the salivary glands is well documented and includes postsurgical complications such as the Frey's syndrome, complete or partial facial nerve damage, facial scarring, greater auricular nerve numbness, sialocoeles and salivary fistula. The avulsion of the salivary duct, secondary strictures, gland swelling, salivary fistulas and perforations (false rout), traumatic ranulas, and the lingual nerve paraesthesia are the main endoscopy-related complications. In general, the rate of postsurgical complications after modern advanced minimally invasive surgical interventions is significantly lower compared with traditional surgery of the salivary glands. Read More

Int J Pediatr Otorhinolaryngol 2017 Jun 5;97:154-156. Epub 2017 Apr 5.

University of Minnesota, Department of Otolaryngology, United States; Children's of Minnesota, Pediatric ENT and Facial Plastic Surgery, United States.

Objective: The aim of this case study is to demonstrate that post-operative complication rates of sublingual gland excision for treatment of ranulas are equal to or less than alternative methods with a lower recurrence rate than other surgical methods.

Methods: This was a retrospective review of pediatric patients from 2004 to 2015 at Children's Hospitals and Clinics of Minnesota. Sixteen ranulas and 6 plunging ranulas were treated via sublingual gland excision during this time frame. Read More

Surg Radiol Anat 2018 Feb 6;40(2):221-225. Epub 2017 May 6.

Department of Natural Sciences and Mathematics, West Liberty University, CSC 139, P.O. Box 295, West Liberty, WV, 26074, USA.

The mylohyoid (MH) musculature separates the sublingual and submandibular spaces and is, therefore, important with regard to the spread of infection and space occupying lesions. Moreover, the MH may be elevated and included in the myocutaneous submental island flap or sutured in conjunction with the platysmas and the anterior bellies of the digastric muscles (ABDMs) to add stability to submental muscular medialization procedures. Therefore, variation in the anatomy of the MH musculature must be considered in the management of the spread of infection and space occupying lesions as well as in surgical planning. Read More

J Surg Case Rep 2017 Apr 4;2017(4):rjx068. Epub 2017 Apr 4.

Histopatholgy Department, Wirral Teaching Hospitals NHS Trust, Arrowe Park Hospital, Wirral CH49 5PE, UK.

Ancient schwannomas are benign, slow-growing tumours derived from the neural sheath. They are characterized by degenerative changes which are not seen in the common schwannoma. An unusual case of ancient schwannoma of the sublingual space is reported to highlight the diagnostic challenge that this tumour presents. Read More

J Maxillofac Oral Surg 2017 Jun 22;16(2):192-196. Epub 2016 Sep 22.

Faculty of Dental Surgery, Lagos State University, Lagos, Nigeria.

Background: A ranula is a cystic lesion in the floor of the mouth, formed either as a retention cyst or pseudocyst as a result of extravasation of mucus in the surrounding tissue. It may be treated by micro-marsupialization, marsupialization or excision of lesion with or without the associated salivary gland. Marsupialization is usually achieved by cutting a slit and thereafter stitching the edges such that the epithelium of the exterior becomes continuous with that of the interior of a cyst. Read More

Laryngoscope 2017 10 13;127(10):2239-2241. Epub 2017 Apr 13.

Department of Otolaryngology, Stanford University School of Medicine, Stanford, California, U.S.A.

Evidence supporting any one treatment for plunging ranula is limited. Standard treatment-complete excision of the sublingual gland and ranula-is invasive and morbid given the close operative proximity to the submandibular duct and lingual nerve. OK-432 (Picibanil; Chugai Pharmaceutical Co. Read More

Head Neck Pathol 2017 Mar 28;11(1):48-54. Epub 2017 Feb 28.

Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA.

The World Health Organization (WHO) 2017 Classification of Head and Neck Tumors ("Blue Book") will now include a new chapter on tumors and tumor-like lesions of the neck and lymph nodes, which was not included in the previous edition. Tumors and tumor-like lesions, including a variety of cysts and metastases, can arise in any component in the neck, including soft tissue, lymph nodes, and developmental remnants. The pathology and clinical features of metastatic carcinoma of unknown primary in the head and neck has changed dramatically in the last several years. Read More

World J Surg 2017 06;41(6):1476-1481

Department of General Surgery, College of Medicine, University of Jos & Jos University Teaching Hospital, Jos, Nigeria.

Background: There is no consensus opinion on a definitive surgical management option for ranulas to curtail recurrence, largely from the existing gap in knowledge on the pathophysiologic basis.

Aim: To highlight the current scientific basis of ranula development that informed the preferred surgical approach.

Design: Retrospective cohort study. Read More

Pediatr Rep 2016 Nov 23;8(4):6576. Epub 2016 Dec 23.

Pediatric Surgery Unit, Department of Maternal and Children's Health, Fondazione IRCCS Policlinico S.Matteo and Department of Clinical, Surgical, Diagnostic and Pediatric Sciences, University of Pavia , Pavia , and Ospedale dei Bambini "G. Di Cristina", A.R.N.A.S. Palermo, Italy.

Few cases of plunging ranulas (PRs) occur during childhood and the lesions are frequently misdiagnosed. Here, a PR in a child is reported along with a literature review. A seven-year-old female complaining of swelling in the midline neck, left-submandibular region, was evaluated. Read More

Oral Surg Oral Med Oral Pathol Oral Radiol 2017 May 22;123(5):e160-e163. Epub 2016 Nov 22.

Division of Oral and Maxillofacial Pathology, Columbia University College of Dental Medicine, New York, NY, USA. Electronic address:

Chronic lymphocytic leukemia (CLL), an indolent neoplasm of B lymphocytes, is the most common adult leukemia in the Western Hemisphere. Despite this, however, the intraoral presentation of CLL is quite rare. We report the case of an 83-year-old woman with CLL incidentally involving minor salivary glands in association with a ranula (floor-of-mouth mucocele). Read More

Ann Otol Rhinol Laryngol 2017 Mar 5;126(3):216-218. Epub 2017 Jan 5.

1 Department of Otolaryngology, Head & Neck Surgery, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, USA.

Objectives: To present a unique series of sublingual gland sialolithiasis treated with sialendoscopy.

Methods: A retrospective chart review of patients at a single tertiary care academic center undergoing sialendoscopy.

Results: We present a series of 4 patients who presented with 1 episode each of sialadenitis without preceding postprandial symptoms. Read More