Int J Mol Sci 2021 May 28;22(11). Epub 2021 May 28.
Health Science Center at San Antonio, Programs in Integrated Biomedical Sciences, Department of Oral & Maxillofacial Surgery, School of Dentistry, Translational Sciences, Biomedical Engineering and Radiological Sciences, University of Texas, San Antonio, TX 78229, USA.
The oral cavity is a portal into the digestive system, which exhibits unique sensory properties. Like facial skin, the oral mucosa needs to be exquisitely sensitive and selective, in order to detect harmful toxins versus edible food. Chemosensation and somatosensation by multiple receptors, including transient receptor potential channels, are well-developed to meet these needs. Read More