1,342,726 results match your criteria Radiology and Imaging Letter[Journal]


[Inflammatory pseudotumor in nasopharynx and retrostyloid space: a case report].

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2019 Feb;54(2):142-144

Department of Otorhinolaryngology, First Affiliated Hospital of China Medical University, Shenyang 110001, China.

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http://dx.doi.org/10.3760/cma.j.issn.1673-0860.2019.02.010DOI Listing
February 2019

[One case of diffuse large B cell lymphoma primarily presenting in sphenoid sinus].

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2019 Feb;54(2):139-140

Department of Radiology, Henan university huaihe hospital, Kaifeng 475000, China.

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http://dx.doi.org/10.3760/cma.j.issn.1673-0860.2019.02.008DOI Listing
February 2019

A retrospective analysis of radiation oncology related scientific articles in the journal Veterinary Radiology and Ultrasound: Trends over 40 years (1976-2015).

Authors:
Koichi Nagata

Vet Radiol Ultrasound 2019 Feb 18. Epub 2019 Feb 18.

College of Veterinary Medicine, Department of Veterinary Biosciences & Diagnostic Imaging, The University of Georgia, Athens, GA 30602.

The journal Veterinary Radiology & Ultrasound is a veterinary specialty journal devoted to the fields of veterinary diagnostic imaging and radiation oncology. The purpose of this retrospective, observational study is to evaluate progressive trends in radiation oncology articles published in Veterinary Radiology & Ultrasound during the 40-year period (1976-2015) and describe a shift of trends through several viewpoints. This 40-year period was divided into four subperiods: Period 1 (1976-1985), Period 2 (1986-1995), Period 3 (1996-2005), and Period 4 (2006-2015). Read More

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http://dx.doi.org/10.1111/vru.12716DOI Listing
February 2019

Dopamine effects on frontal cortical blood flow and motor inhibition in Parkinson's disease.

Cortex 2019 Jan 29;115:99-111. Epub 2019 Jan 29.

Neurology, Vanderbilt University Medical Center, Nashville, TN, USA. Electronic address:

Parkinson's disease (PD) is characterized by dysfunction in frontal cortical and striatal networks that regulate action control. We investigated the pharmacological effect of dopamine agonist replacement therapy on frontal cortical activity and motor inhibition. Using Arterial Spin Labeling MRI, we examined 26 PD patients in the off- and on-dopamine agonist medication states to assess the effect of dopamine agonists on frontal cortical regional cerebral blood flow. Read More

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http://dx.doi.org/10.1016/j.cortex.2019.01.016DOI Listing
January 2019

Cerebrovascular disease burden in late-onset non-lesional focal epilepsy.

Seizure 2019 Feb 8;66:31-35. Epub 2019 Feb 8.

Epilepsy Unit, Neurology Department, Vall d'Hebron University Hospital, Autonomous University of Barcelona, Barcelona, Spain. Electronic address:

Purpose: Late-onset non-lesional focal epilepsy, defined as new-onset seizures in patients older than 60 years, is diagnosed increasingly more often in relation to aging of the population. It has been attributed mainly to occult cerebral small vessel disease (SVD), although high levels of evidence to support this notion are lacking. This study aimed to evaluate the burden of leukoaraiosis, a marker of cerebral SVD, and hippocampal atrophy in patients with late-onset epilepsy (LOE). Read More

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http://dx.doi.org/10.1016/j.seizure.2019.02.004DOI Listing
February 2019

Activation of ATP-sensitive K-channel promotes the anticonvulsant properties of cannabinoid receptor agonist through mitochondrial ATP level reduction.

Epilepsy Behav 2019 Feb 15;93:1-6. Epub 2019 Feb 15.

Brain and Spinal Cord Injury Research Center, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran; Experimental Medicine Research Center, Tehran University of Medical Sciences, Tehran, Iran. Electronic address:

Cannabinoid receptor (CBR) agonist could act as a protective agent against seizure susceptibility in animal models of epilepsy. Studies have shown that potassium channels could play a key role in ameliorating neuronal excitability. In this study, we attempted to evaluate how CBRs and Adenosine Tri-Phosphate (ATP)-sensitive potassium channels collaborate to affect seizure susceptibility by changing the clonic seizure threshold (CST). Read More

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http://dx.doi.org/10.1016/j.yebeh.2019.01.025DOI Listing
February 2019

Grading of hepatocellular carcinoma using 3D SE-DenseNet in dynamic enhanced MR images.

Comput Biol Med 2019 Feb 4;107:47-57. Epub 2019 Feb 4.

Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou, 215163, China. Electronic address:

Background: Clinical histological grading of hepatocellular carcinoma (HCC) differentiation is of great significance in clinical diagnoses, treatments, and prognoses. However, it is challenging for radiologists to evaluate HCC gradings from medical images.

Purpose: In this study, a novel deep neural network was developed by combining the squeeze-and-excitation networks (SENets) in a three-dimensional (3D) densely connected convolutional network (DenseNet), which is referred to as a 3D SE-DenseNet, for the classification of HCC grading using enhanced clinical magnetic resonance (MR) images obtained from two different clinical centers. Read More

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http://dx.doi.org/10.1016/j.compbiomed.2019.01.026DOI Listing
February 2019

The influence of tau, amyloid, alpha-synuclein, TDP-43, and vascular pathology in clinically normal elderly individuals.

Neurobiol Aging 2019 Jan 21;77:26-36. Epub 2019 Jan 21.

Department of Neurology, Mayo Clinic, Rochester, MN, USA. Electronic address:

Many individuals live to older ages without clinical impairment. It is unknown whether brain pathologies in these individuals are associated with subtle clinical deficits. We analyzed the brains of 161 clinically normal (Clinical Dementia Rating score = 0) older individuals enrolled in the Mayo Clinic Patient Registry or Study of Aging. Read More

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http://dx.doi.org/10.1016/j.neurobiolaging.2019.01.008DOI Listing
January 2019

Inclusion complex of saikosaponin-d with hydroxypropyl-β-cyclodextrin: Improved physicochemical properties and anti-skin cancer activity.

Phytomedicine 2018 Nov 8;57:174-182. Epub 2018 Nov 8.

Department of Fragrance and Cosmetic Science, College of Pharmacy, Kaohsiung Medical University, Kaohsiung, Taiwan; Institute of Biomedical Sciences, National Sun Yat-Sen University, Kaohsiung, Taiwan. Electronic address:

Background: Saikosaponin-d (SSD) is a triterpene saponin isolated from Bupleurum plants. It has been shown to exhibit antioxidant, anti-inflammatory, and anticancer activities. However, its biomedical applications are limited by its poor water solubility. Read More

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http://dx.doi.org/10.1016/j.phymed.2018.11.012DOI Listing
November 2018

Indocyanine Green and Contrast-enhanced Ultrasound videoangiography: a synergistic approach for real time verification of distal revascularization and aneurysm occlusion in a complex distal middle cerebral artery aneurysm.

World Neurosurg 2019 Feb 15. Epub 2019 Feb 15.

Oncological Neurosurgery Unit, Department of Neurosurgery, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy; Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy.

Background: Distal outflow occlusion and extracranial-intracranial bypass represent a possible option for the surgical management of complex middle cerebral artery (MCA) aneurysm. A limitation of distal clipping strategy combined to bypass relies on the difficulties in predicting intraoperatively the good blood flow supply to the brain territory distal to the aneurysm and the extent and speed of aneurysmal thrombosis.

Methods: The authors presented an innovative approach in which Contrast-enhanced US (CEUS) and indocyanine green video-angiography (ICG-VA) have been synergistically used to study the effect of distal clipping on the aneurysm flow and the parenchymal blood flow after the bypass. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.01.241DOI Listing
February 2019

Refractory diet-dependent changes in neural microstructure: Implications for microstructural endophenotypes of neurologic and psychiatric disease.

Magn Reson Imaging 2019 Feb 15. Epub 2019 Feb 15.

Department of Biomedical Engineering, College of Engineering, University of Wisconsin-Madison, Madison, WI 53706, USA; Department of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53705, USA; Neuroscience Training Program, Wisconsin Institutes for Medical Research, University of Wisconsin-Madison, Madison, WI 53705, USA; Department of Psychiatry, University of Wisconsin School of Medicine and Public Health, Madison, WI 53705, USA. Electronic address:

Alterations in gut microbiome populations via dietary manipulation have been shown to induce diet-dependent changes in white matter microstructure. The purpose of this study is to examine the durability of these diet-induced microstructural alterations. We implemented a crossover experimental design where post-weaned male rats were assigned to one of four experimental diets. Read More

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http://dx.doi.org/10.1016/j.mri.2019.02.006DOI Listing
February 2019

Pravastatin Reverses Established Radiation-Induced Cutaneous and Subcutaneous Fibrosis in Patients with Head and Neck Cancer: Results of the Biology-Driven Phase Ii Clinical Trial Pravacur.

Int J Radiat Oncol Biol Phys 2019 Feb 15. Epub 2019 Feb 15.

Radiation Oncology Department, CHUV Lausanne, Switzerland.

Purpose: The "xxx" phase II trial (NCTxxx) assessed the efficacy of pravastatin as anti-fibrotic agent in patients with established cutaneous and subcutaneous radiation-induced fibrosis (RIF) after head and neck squamous cell carcinoma (HNSCC) radiotherapy and/or radio-chemotherapy.

Methods And Materials: The main inclusion criteria were: patients with HNSCC in remission, with grade ≥2 cutaneous and subcutaneous neck RIF (NCI-CTCAE v4.0); no current treatment with statins or fibrates. Read More

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http://dx.doi.org/10.1016/j.ijrobp.2019.02.024DOI Listing
February 2019

Prospective Multicentered Safety and Feasibility Pilot for Endobronchial Intratumoral Chemotherapy.

Chest 2019 Feb 15. Epub 2019 Feb 15.

Section of Interventional Pulmonology, Division of Pulmonary, Allergy and Critical Care Medicine, Duke University, Durham, NC.

Background: Malignant airway obstruction (MAO) occurs in 30% of patients with advanced stage lung cancer leading to debilitating dyspnea, cough and hemoptysis. Other than recanalization of the airways, these patients lack long-lasting palliative therapy. The goal of this study was to determine the safety and feasibility of local injection of paclitaxel into the airway wall with a novel microinjection catheter. Read More

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http://dx.doi.org/10.1016/j.chest.2019.02.006DOI Listing
February 2019

Diagnosis of hepatic nodules in patients at risk for hepatocellular carcinoma: LIRADS probability vs certainty.

Gastroenterology 2019 Feb 15. Epub 2019 Feb 15.

BCLC group. Radiology Department. Hospital Clínic. IDIBAPS. CIBEREHD. University of Barcelona.

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http://dx.doi.org/10.1053/j.gastro.2019.02.008DOI Listing
February 2019

Is It Appropriate to Place Subcutaneous Chest Ports in Patients with Neutropenia?

Authors:
Evan J Johnson

Radiology 2019 Feb 12:190095. Epub 2019 Feb 12.

From the Department of Radiology, Mayo Clinic, 200 First St SW, Rochester, MN 55905.

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http://dx.doi.org/10.1148/radiol.2019190095DOI Listing
February 2019

MRI for First-Line Evaluation of Children Suspected of Having Acute Appendicitis.

Radiology 2019 Feb 12:190056. Epub 2019 Feb 12.

From the Department of Radiology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Ave, Cincinnati, OH 45229; and Department of Radiology, University of Cincinnati College of Medicine, Cincinnati, Ohio.

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http://dx.doi.org/10.1148/radiol.2019190056DOI Listing
February 2019

Correlation between EGFR mutation status and F -fluorodeoxyglucose positron emission tomography-computed tomography image features in lung adenocarcinoma.

Thorac Cancer 2019 Feb 18. Epub 2019 Feb 18.

Department of Molecular Imaging and Nuclear Medicine, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China.

Background: The purpose of this study was to investigate an association between EGFR mutation status and F-fluorodeoxyglucose positron emission tomography-computed tomography ( F-FDG PET-CT) image features in lung adenocarcinoma.

Methods: Retrospective analysis of the data of 139 patients with lung adenocarcinoma confirmed by surgical pathology who underwent preoperative F-FDG PET-CT was conducted. Correlations between EGFR mutation status, clinical characteristics, and PET-CT parameters, including the maximum standardized uptake value (SUVmax), the mean of the SUV (SUVmean), the peak of the SUV (SUVpeak) of the primary tumor, and the ratio of SUVmax between the primary tumor and the mediastinal blood pool (SUVratio), were statistically analyzed. Read More

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http://dx.doi.org/10.1111/1759-7714.12981DOI Listing
February 2019

Safety and effectiveness of alectinib in a real-world surveillance study in patients with ALK-positive NSCLC in Japan.

Cancer Sci 2019 Feb 18. Epub 2019 Feb 18.

Third Department of Internal Medicine, Division of Pulmonary Medicine & Medical Oncology, Wakayama Medical University, Wakayama, Japan.

We conducted a large-scale surveillance study as a post-marketing commitment to investigate safety and effectiveness of alectinib in patients with ALK-positive non-small-cell lung cancer (NSCLC) in Japan. Patients receiving 300mg twice-daily alectinib (September 2014 to June 2015) were monitored until termination of alectinib or completion of 18 months of treatment at 519 Japanese study sites. The primary endpoint was the incidence of adverse drug reactions (ADRs), which are important identified risks for alectinib in Japanese patients. Read More

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http://dx.doi.org/10.1111/cas.13977DOI Listing
February 2019

Novel, anatomically appropriate balloon dilation technique of the glottis to treat posterior glottic stenosis in a 3D-printed model.

Laryngoscope 2019 Feb 18. Epub 2019 Feb 18.

Department of Otolaryngology, University of Pittsburgh, Pittsburgh, Pennsylvania, U.S.A.

Objective: Posterior glottic stenosis (PGS) often requires a destructive surgical treatment. Early PGS treatment involves glottic dilation to reduce airway constriction associated with chronic PGS. Round laryngeal dilation may not optimize posterior glottic dilation due to the teardrop shape of the glottis and may injure vocal fold tissue. Read More

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http://dx.doi.org/10.1002/lary.27524DOI Listing
February 2019

Deep White Matter Lesions Are Associated with Early Recognition of Dementia in Alzheimer's Disease.

J Alzheimers Dis 2019 Feb 11. Epub 2019 Feb 11.

Department of Neurology, Gunma University Graduate School of Medicine, Maebashi, Japan.

Neuroimages of cerebral amyloid-β (Aβ) accumulation and small vessel disease (SVD) were examined in patients with various types of cognitive disorders using 11C-labeled Pittsburgh Compound B-positron emission tomography (PiB-PET) and magnetic resonance imaging (MRI). The mean cortical standardized uptake value ratio (mcSUVR) was applied for a quantitative analysis of PiB-PET data. The severity of white matter lesions (WML) and enlarged perivascular spaces (EPVS) on MRI were assessed to evaluate complicating cerebral SVD using semiquantitative scales. Read More

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http://dx.doi.org/10.3233/JAD-180939DOI Listing
February 2019

The Clinical Phenotype of Vascular Cognitive Impairment in Patients with Type 2 Diabetes Mellitus.

J Alzheimers Dis 2019 Feb 8. Epub 2019 Feb 8.

Department of Neurology, Brain Center Rudolph Magnus, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.

Background: Type 2 diabetes mellitus (T2DM) increases the risk of vascular cognitive impairment (VCI). It is unknown which type of vascular lesions and co-morbid etiologies, in particular Alzheimer's disease pathology, are associated with T2DM in patients with VCI, and how this relates to cognition and prognosis.

Objective: To compare brain MRI and cerebrospinal fluid (CSF) markers, cognition, and prognosis in patients with possible VCI with and without T2DM. Read More

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http://dx.doi.org/10.3233/JAD-180914DOI Listing
February 2019

Distinctive Neurochemistry in Alzheimer's Disease via 7 T In Vivo Magnetic Resonance Spectroscopy.

J Alzheimers Dis 2019 Feb 11. Epub 2019 Feb 11.

Center for Magnetic Resonance Research and Department of Radiology, University of Minnesota, Minneapolis, MN, USA.

This study's objective was to increase understanding of biological mechanisms underlying clinical Alzheimer's disease (AD) by noninvasively measuring an expanded neurochemical profile and exploring how well this advanced technology distinguishes AD from cognitively normal controls. We measured concentrations of 14 neurochemicals using ultra-high field (7 T) ultra-short echo time (8 ms) magnetic resonance spectroscopy (MRS) in 16 participants with mild to moderate clinical AD and 33 age- and gender-matched control participants. MRS was localized to the posterior cingulate cortex (PCC), a region known to be impacted by AD, and the occipital cortex (OCC), a control region. Read More

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http://dx.doi.org/10.3233/JAD-180861DOI Listing
February 2019

Cognitive Reserve in Midlife is not Associated with Amyloid-β Deposition in Late-Life.

J Alzheimers Dis 2019 Feb 11. Epub 2019 Feb 11.

Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

We examined associations between cognitive reserve and late-life amyloid-β deposition using florbetapir positron emission tomography (PET). We used data from the Atherosclerosis Risk in Communities (ARIC) and ARIC-PET Study. 330 dementia-free participants underwent PET scans. Read More

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http://dx.doi.org/10.3233/JAD-180785DOI Listing
February 2019

The Potential of Photoacoustic Techniques for Molecular Imaging.

Authors:
Reuben S Mezrich

Radiology 2019 Feb 12:190125. Epub 2019 Feb 12.

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http://dx.doi.org/10.1148/radiol.2019190125DOI Listing
February 2019

In vivo comparison of shape memory polymer foam-coated and bare metal coils for aneurysm occlusion in the rabbit elastase model.

J Biomed Mater Res B Appl Biomater 2019 Feb 18. Epub 2019 Feb 18.

Department of Biomedical Engineering, Texas A&M University, College Station, Texas.

Shape memory polymer (SMP) foam-coated coils (FCCs) are new embolic coils coated with porous SMP designed to expand for increased volume filling and enhanced healing after implantation. The purpose of this study was to compare chronic aneurysm healing after treatment with SMP FCCs to bare platinum coil (BPC) controls in the rabbit elastase aneurysm model. BPCs or SMP FCCs were implanted in rabbit elastase-induced aneurysms for follow-up at 30 days (n = 10), 90 days (n = 5), and 180 days (n = 12 for BPCs; n = 14 for SMP FCCs). Read More

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http://dx.doi.org/10.1002/jbm.b.34337DOI Listing
February 2019

Unusual radiographic images of radiopaque contrast media incidentally observed in intracranial region: two case reports.

Eur Oral Res 2018 Sep 1;52(3):167-169. Epub 2018 Sep 1.

Department of Dentomaxillofacial Radiology, Gazi University, Faculty of Dentistry, Ankara, Turkey.

The oil-based contrast medium has extremely slow clearance rate from cerebrospinal fluid. The medium known as myodil or pantopaque or iopenydylate was firstly introduced in 1944 to be used in myelography, cisternography and ventriculography. It was commonly used until 1980s but was later replaced by water-soluble mediums in 1990s because of its complication and sequelae. Read More

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http://dx.doi.org/10.26650/eor.2018.532DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365132PMC
September 2018

Evaluation of salivary tumour necrosis factor-alpha in patients with recurrent aphthous stomatitis.

Eur Oral Res 2018 Sep 1;52(3):157-161. Epub 2018 Sep 1.

Department of Oral Medicine and Radiology, A B Shetty Memorial Institute of Dental Sciences, Nitte University, Mangalore, India.

Purpose: Present study was undertaken to evaluate and compare the salivary levels of tumour necrosis factor alpha (TNF-α) in subjects with RAS, traumatic ulcers (TUs) in the oral mucosa and in healthy controls.

Materials And Methods: Present study involved 90 participants of which 30 subjects were diagnosed with RAS, 30 subjects with TUs and 30 healthy controls grouped as group 1, group 2 and group 3 respectively. Unstimulated saliva was collected from the subjects through 'Spit Technique' and the estimation of TNF-α was done by enzyme linked immunosorbent assay. Read More

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http://dx.doi.org/10.26650/eor.2018.543DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365135PMC
September 2018

analysis of maxillary first molars morphology using three dimensional Micro-CT imaging: considerations for restorative dentistry.

Eur Oral Res 2018 May 1;52(2):75-81. Epub 2018 May 1.

Department of Dentomaxillofacial Radiology, Ankara University Faculty of Dentistry, Ankara, Turkey.

Purpose: The aim of this study was to determine the differences between the positional relationship of the crown contour and the pulp chamber of left and right maxillary first molars, as well as their morphological characteristics by using micro-CT system with reconstruction from a volumetric rendering software.

Materials And Methods: In total, 21 extracted maxillary first molars, including 11 left and 10 right teeth, were used. The positional relationship between the crown contour, pulp chamber and morphology of the teeth were investigated three-dimensionally by means of micro-CT imaging. Read More

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http://dx.doi.org/10.26650/eor.2018.448DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365124PMC

Transoral flexible laryngoscope biopsy: Safety and accuracy.

World J Otorhinolaryngol Head Neck Surg 2019 Mar 17;5(1):30-33. Epub 2018 Nov 17.

Department of ENT Head & Neck Surgery, Shaheed Mohtarma Benazir Bhutto Medical College & Lyari General Hospital, Karachi, Pakistan.

Objective: To determine the accuracy of transoral flexible laryngoscope (TFL) biopsy and also to identify the safety as office based procedure in terms of complications.

Methods: This is a diagnostic study; the type of intervention is outpatient department based biopsy of laryngeal lesions. All patients seen in ENT outpatient department of Lyari General Hospital with suspicious lesions of Larynx were referred for Transoral Flexible Laryngoscopy Biopsy under local anesthesia. Read More

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http://dx.doi.org/10.1016/j.wjorl.2018.09.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364665PMC

A 3D-Printed Patient-Specific Phantom for External Beam Radiation Therapy of Prostate Cancer.

J Eng Sci Med Diagn Ther 2018 Nov 6;1(4). Epub 2018 Aug 6.

Department of Radiology, Boston Medical Center & Boston University School of Medicine, 820 Harrison Ave., Boston, MA 02118.

This paper presents the design evolution, fabrication, and testing of a novel patient and organ-specific, 3D printed phantom for external beam radiation therapy of prostate cancer. In contrast to those found in current practice, this phantom can be used to plan and validate treatment tailored to an individual patient. It contains a model of the prostate gland with a dominant intraprostatic lesion, seminal vesicles, urethra, ejaculatory duct, neurovascular bundles, rectal wall, and penile bulb generated from a series of combined T2-weighted/dynamic contrast-enhanced magnetic resonance images. Read More

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http://dx.doi.org/10.1115/1.4040817DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376205PMC
November 2018

Positron Emission Tomography Imaging of the Gastrin-Releasing Peptide Receptor with a Novel Bombesin Analogue.

ACS Omega 2019 Jan 16;4(1):1470-1478. Epub 2019 Jan 16.

Department of Molecular Oncology, BC Cancer Research Centre, 675 West 10th Avenue, V5Z 1L3 Vancouver, British Columbia, Canada.

The gastrin-releasing peptide receptor (GRPR), a G protein-coupled receptor, is overexpressed in solid malignancies and particularly in prostate cancer. We synthesized a novel bombesin derivative, [Ga]Ga-ProBOMB1, evaluated its pharmacokinetics and potential to image GRPR expression with positron emission tomography (PET), and compared it with [Ga]Ga-NeoBOMB1. ProBOMB1 (DOTA-pABzA-DIG-d-Phe-Gln-Trp-Ala-Val-Gly-His-Leu-ψ(CHN)-Pro-NH) was synthesized by solid-phase peptide synthesis. Read More

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http://dx.doi.org/10.1021/acsomega.8b03293DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372246PMC
January 2019

Left Ventricular Structure in Patients With Mild-to-Moderate CKD-a Magnetic Resonance Imaging Study.

Kidney Int Rep 2019 Feb 11;4(2):267-274. Epub 2018 Oct 11.

Department of Nephrology and Hypertension, Friedrich-Alexander Universität Erlangen-Nürnberg, Erlangen, Germany.

Introduction: The high burden of left ventricular (LV) abnormalities in patients with advanced chronic kidney disease (CKD) is well established. However, less is known about the prevalence, patterns, and determinants of LV abnormalities in patients with early CKD.

Methods: We examined LV structure in 290 patients with a median estimated glomerular filtration rate (eGFR) of 51 ml/min per 1. Read More

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http://dx.doi.org/10.1016/j.ekir.2018.10.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365352PMC
February 2019

Intima media thickness as an early predictor of atherosclerosis in Egyptian children with familial Mediterranean fever.

Arch Med Sci Atheroscler Dis 2018 7;3:e106-e111. Epub 2018 Aug 7.

Department of Pediatrics, National Research Centre, Dokki, Egypt.

Introduction: Familial Mediterranean fever (FMF) is an autosomal recessive disease. It is characterized by recurrent crises of fever and serosal inflammation. Although FMF patients are symptom free in between attacks, subclinical inflammation continues during the attack-free period. Read More

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http://dx.doi.org/10.5114/amsad.2018.77545DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374578PMC

An quality assurance study of contouring target volumes in thoracic tumors within a cooperative group setting.

Clin Transl Radiat Oncol 2019 Feb 6;15:83-92. Epub 2019 Jan 6.

Department of Radiation Oncology, University of Texas M.D. Anderson Cancer Center, TX 77030, USA.

Introduction: Target delineation variability is a significant technical impediment in multi-institutional trials which employ intensity modulated radiotherapy (IMRT), as there is a real potential for clinically meaningful variances that can impact the outcomes in clinical trials. The goal of this study is to determine the variability of target delineation among participants from different institutions as part of Southwest Oncology Group (SWOG) Radiotherapy Committee's multi-institutional quality assurance study in patients with Pancoast tumors as a "dry run" for trial implementation.

Methods: CT simulation scans were acquired from four patients with Pancoast tumor. Read More

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http://dx.doi.org/10.1016/j.ctro.2019.01.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365802PMC
February 2019

Human consciousness is supported by dynamic complex patterns of brain signal coordination.

Sci Adv 2019 Feb 6;5(2):eaat7603. Epub 2019 Feb 6.

INSERM, U 1127, F-75013 Paris, France.

Adopting the framework of brain dynamics as a cornerstone of human consciousness, we determined whether dynamic signal coordination provides specific and generalizable patterns pertaining to conscious and unconscious states after brain damage. A dynamic pattern of coordinated and anticoordinated functional magnetic resonance imaging signals characterized healthy individuals and minimally conscious patients. The brains of unresponsive patients showed primarily a pattern of low interareal phase coherence mainly mediated by structural connectivity, and had smaller chances to transition between patterns. Read More

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http://dx.doi.org/10.1126/sciadv.aat7603DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365115PMC
February 2019

Cardiovascular magnetic resonance T2* mapping for structural alterations in hypertrophic cardiomyopathy.

Eur J Radiol Open 2019 4;6:78-84. Epub 2019 Feb 4.

Department of Cardiology, University Heart Center, University Hospital Zurich, Raemistrasse 100, 8091, Zurich, Switzerland.

Purpose: Hypertrophic cardiomyopathy (HCM) is characterized by a heterogeneous morphology and variable prognosis. A mismatch between left ventricular mass (LVM) and microvascular circulation with corresponding relative ischemia has been implicated to cause myocardial replacement fibrosis that deteriorates prognosis. Besides parametric T1 mapping, Cardiovascular Magnetic Resonance (CMR) T2* mapping is able to identify ischemia as well as fibrosis in cardiac and extracardiac diseases. Read More

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http://dx.doi.org/10.1016/j.ejro.2019.01.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365365PMC
February 2019

Clinical Characteristics and Radiologic Features of Immunocompromised Patients With Pauci-Bacillary Pulmonary Tuberculosis Receiving Delayed Diagnosis and Treatment.

Open Forum Infect Dis 2019 Feb 17;6(2):ofz002. Epub 2019 Jan 17.

Departments of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.

Background: Pauci-bacillary pulmonary tuberculosis (TB) can be delayed to diagnose and start anti-TB therapy, especially in immunocompromised patients. We therefore evaluated the clinical and radiologic features of these delayed cases.

Methods: Immunocompromised adult patients with pauci-bacillary pulmonary TB were retrospectively enrolled in a tertiary hospital in an intermediate-TB burden country over a 5-year period. Read More

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http://dx.doi.org/10.1093/ofid/ofz002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366656PMC
February 2019

Pulmonary veno-occlusive disease is highly prevalent in scleroderma patients undergoing lung transplantation.

ERJ Open Res 2019 Feb 11;5(1). Epub 2019 Feb 11.

Division of Pulmonary Medicine, Dept of Medicine, National Jewish Health, Denver, CO, USA.

http://ow.ly/vPvc30neJZV. Read More

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http://dx.doi.org/10.1183/23120541.00168-2018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368993PMC
February 2019

Central Venous Sinus Thrombosis in a Boy With Acute Severe Ulcerative Colitis.

Front Pediatr 2019 1;7:19. Epub 2019 Feb 1.

Pediatric Gastroenterology and Nutrition Unit, Hospital Regional Universitario de Malaga, Málaga, Spain.

Cerebral venous sinus thrombosis (CVST) in childhood is uncommon. Certain diseases predispose patients to CVST, such as inflammatory bowel disease (IBD), which is considered a risk factor for developing thrombosis, which in turn is considered an extraintestinal manifestation of IBD. The use of prophylaxis in certain patients is a controversial topic. Read More

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http://dx.doi.org/10.3389/fped.2019.00019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367252PMC
February 2019

An unusual variant of scimitar syndrome predisposing to recurrent pneumonia.

Respir Med Case Rep 2019 23;26:240-243. Epub 2019 Jan 23.

Division of Pulmonary Medicine, Mayo Clinic, Phoenix, AZ, USA.

Scimitar syndrome is a rare constellation of congenital conditions pertaining to partial anomalous pulmonary venous return. Radiographically, these anomalous pulmonary veins can resemble a scimitar, and have heterogeneous clinical presentations. We present an unusual case of scimitar syndrome with associated recurrent pneumonia. Read More

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http://dx.doi.org/10.1016/j.rmcr.2019.01.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366150PMC
January 2019

Regularized reconstruction based on joint L and total variation for sparse-view cone-beam X-ray luminescence computed tomography.

Biomed Opt Express 2019 Jan 3;10(1):1-17. Epub 2018 Dec 3.

Department of Biomedical Engineering, Fourth Military Medical University, Xi'an, Shaanxi 710032, China.

As an emerging hybrid imaging modality, cone-beam X-ray luminescence computed tomography (CB-XLCT) has been proposed based on the development of X-ray excitable nanoparticles. Owing to the high degree of absorption and scattering of light through tissues, the CB-XLCT inverse problem is inherently ill-conditioned. Appropriate priors or regularizations are needed to facilitate reconstruction and to restrict the search space to a specific solution set. Read More

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http://dx.doi.org/10.1364/BOE.10.000001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363206PMC
January 2019

Compression of the middle cerebellar tract by posterior fossa tumors before and after Gamma Knife radiosurgery studied with diffusion tensor imaging.

J Radiosurg SBRT 2019 ;6(1):11-17

Centro Gamma Knife Dominicano, CEDIMAT, Plaza de la Salud, Santo Domingo, Dominican Republic.

Purpose: To investigate if clinically asymptomatic compression of the middle cerebellar tract by extracerebral posterior fossa tumors can produce changes in diffusion tensor imaging (DTI) parameters and if these changes return to normal after Gamma Knife radiosurgery (GKRS).

Material And Methods: In 22 patients (12 female, mean age 53.8 years) with posterior fossa tumors (14 schwannomas and 8 meningiomas), the middle cerebellar tract was tracked using DTI data. Read More

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January 2019

Caecal Epiploic Appendagitis Masquerading Clinically as an Acute Appendicitis: A Case Report and Brief Literature Review.

Case Rep Surg 2019 15;2019:6508642. Epub 2019 Jan 15.

Department of Radiology, Midland Regional Hospital Mullingar, Longford Road, Mullingar, Co-Westmeath, Ireland.

A 46-year-old female presented to our emergency department (ED) with a 2-day history of right lower abdominal pain which was associated with nausea and anorexia. Abdominal examination revealed tenderness in the right iliac fossa (RIF) with rebound tenderness and a localized guarding. Urine dipstick was normal, and the pregnancy test was negative. Read More

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http://dx.doi.org/10.1155/2019/6508642DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350580PMC
January 2019

Gross handling of pulmonary resection specimen: maintaining the 3-dimensional orientation.

J Thorac Dis 2019 Jan;11(Suppl 1):S37-S44

Department of Pathology Amsterdam University Medical Centers, VU University Medical Center, De Boelelaan 1117, Amsterdam, The Netherlands.

There is limited literature on the gross handling of lung resection specimens. Microscopic examination of the specimen, TNM staging and predictive biomarker testing are fully dependent on an adequate gross handling. In this paper, we present a 3-dimensional (3D) grossing method of oncological lung resection specimens, which ensures proper fixation of the tumor tissue, but also enables accurate correlation with the pre-surgical imaging. Read More

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http://dx.doi.org/10.21037/jtd.2018.12.36DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353737PMC
January 2019

The impact of ionizing irradiation on liver detoxifying enzymes. A re-investigation.

Cell Death Discov 2019 8;5:66. Epub 2019 Feb 8.

1Department of Chemical Sciences and Technologies, University of Rome "Tor Vergata", Rome, Italy.

By looking at many studies describing the impact of ionizing irradiations in living mice on a few key detoxifying enzymes like catalase, superoxide dismutase, glutathione peroxidase, glutathione reductase and glutathione transferase, we noted conflicting evidences: almost all papers finalized to demonstrate the protective effects of natural or synthetic drugs against the damage by irradiations, described also a relevant inactivation of these enzymes in the absence of these compounds. Conversely, no inactivation and even enhanced activity has been noted under similar irradiation modality in all studies supporting the "adaptive response". Motivated by these curious discrepancies, we performed irradiation experiments on living mice, explanted mouse livers and liver homogenates observing that, in all conditions the activity of all these enzymes remained almost unchanged except for a slight increase found in explanted livers. Read More

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http://dx.doi.org/10.1038/s41420-019-0148-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368569PMC
February 2019

Clinical outcome of closed reduction of cervical spine injuries in a cohort of Nigerians.

Spinal Cord Ser Cases 2019 12;5:17. Epub 2019 Feb 12.

1Department of Surgery, College of Medicine, University of Ibadan, Ibadan, Nigeria.

Study Design: A prospective observational study.

Objectives: To evaluate the effectiveness of closed reduction of cervical spine injuries (CSIs) using cervical traction and identify probable complications.

Setting: Department of Neurological Surgery, University College Hospital, Ibadan, Nigeria. Read More

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http://dx.doi.org/10.1038/s41394-019-0158-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372639PMC
February 2019

Idiopathic pulmonary fibrosis: prognostic impact of histologic honeycombing in transbronchial lung cryobiopsy.

Multidiscip Respir Med 2019 8;14. Epub 2019 Feb 8.

1Department of Thoracic Diseases, G.B. Morgagni - L. Pierantoni Hospital, Via C. Forlanini 34, 47121 Forlì, FC Italy.

Background: Prognostic evaluation in idiopathic pulmonary fibrosis (IPF) may be important as it can guide management decisions, but the potential role of honeycomb changes in providing information about outcome and survival of patients with IPF, particularly if diagnosed using cryobiopsy, has not been evaluated. Aim of this study was to determinate whether a relationship exists between honeycombing on cryobiopsy and clinical/radiological picture and outcome in patients with IPF and to assess whether the same pathologic criteria that have been used to define the UIP pattern (usual interstitial pneumonia) for surgical biopsy can also be applied to cryobiopsy.

Methods: Sixty-three subjects with a multidisciplinary diagnosis of IPF and a UIP pattern on cryobiopsy were evaluated. Read More

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http://dx.doi.org/10.1186/s40248-019-0170-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367843PMC
February 2019

Fully Convolutional DenseNet with Multiscale Context for Automated Breast Tumor Segmentation.

J Healthc Eng 2019 14;2019:8415485. Epub 2019 Jan 14.

National Digital Switching System Engineering and Technological Research Center, Zhengzhou, Henan Province, China.

Breast tumor segmentation plays a crucial role in subsequent disease diagnosis, and most algorithms need interactive prior to firstly locate tumors and perform segmentation based on tumor-centric candidates. In this paper, we propose a fully convolutional network to achieve automatic segmentation of breast tumor in an end-to-end manner. Considering the diversity of shape and size for malignant tumors in the digital mammograms, we introduce multiscale image information into the fully convolutional dense network architecture to improve the segmentation precision. Read More

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http://dx.doi.org/10.1155/2019/8415485DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350548PMC
January 2019

Effects of Folate Supplementation on Carotid Intima-Media Thickness, Biomarkers of Inflammation, and Oxidative Stress in Carbamazepine-Treated Epileptic Children.

Int J Prev Med 2019 15;10. Epub 2019 Jan 15.

Research Center for Biochemistry and Nutrition in Metabolic Diseases, Kashan University of Medical Sciences, Kashan, I.R. Iran.

Background: This study was conducted to assess the effects of folate supplementation on carotid intima-media thickness (CIMT), biomarkers of inflammation, and oxidative stress in carbamazepine-treated epileptic children.

Methods: This randomized, double-blind, placebo-controlled trial was carried out in 54 epileptic children aged 2-12 years old receiving carbamazepine monotherapy. Participants were randomly allocated into two groups to receive either 5 mg folate supplements or placebo ( = 27 in each group) for 12 weeks. Read More

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http://dx.doi.org/10.4103/ijpvm.IJPVM_152_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360991PMC
January 2019

Correction to: Efficacy of radiographic density values of the first and second cervical vertebrae recorded by CBCT technique to identify patients with osteoporosis and osteopenia.

J Dent Res Dent Clin Dent Prospects 2018 19;12(4):304. Epub 2018 Dec 19.

Dental and Periodontal Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.

[This corrects the article DOI: 10.15171/joddd.2017. Read More

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http://dx.doi.org/10.15171/joddd.2018.048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368949PMC
December 2018
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