20,097 results match your criteria REM Sleep Behavior Disorder


Protective effects of REM sleep without atonia against obstructive sleep apnea in patients with idiopathic REM sleep behavior disorder.

Sleep Med 2018 Nov 19;54:116-120. Epub 2018 Nov 19.

Department of Neurology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea. Electronic address:

Background: This study investigated the protective effect of rapid eye movement (REM) sleep without atonia against obstructive sleep apnea (OSA) in patients with idiopathic REM sleep behavior disorder (RBD).

Methods: In this case-control study, patients with idiopathic RBD and OSA (RBD-OSA) were consecutively enrolled and OSA controls without RBD were matched for age, sex, and apnea-hypopnea index (AHI). Clinical and polysomnographic characteristics were compared between RBD-OSA patients and OSA controls. Read More

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November 2018

Higher sleep spindle activity is associated with fewer false memories in adolescent girls.

Neurobiol Learn Mem 2018 Dec 12. Epub 2018 Dec 12.

Department of Psychology and Logopedics, Faculty of Medicine, University of Helsinki, Helsinki, Finland.

Background: Sleep facilitates the extraction of semantic regularities amongst newly encoded memories, which may also lead to increased false memories. We investigated sleep stage proportions and sleep spindles in the recollection of adolescents' false memories, and their potential sex-specific differences.

Methods: 196 adolescents (mean age 16. Read More

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December 2018

Association between α-adducin rs4961 polymorphism and hypertension: A meta-analysis based on 40 432 subjects.

J Cell Biochem 2018 Dec 14. Epub 2018 Dec 14.

Department of Cardiology, Hanyang hospital of Wuhan University of Science and Technology, Hanyang, Wuhan, China.

Background: Recently, the role of α-adducin rs4961 polymorphism in hypertension (HTN) was intensively analyzed, but the results of these studies were inconsistent. Therefore, we performed this study to better assess the relationship between α-adducin rs4961 polymorphism and the likelihood of HTN.

Methods: Eligible studies were searched in PubMed, Medline, Embase, and Web of Science. Read More

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December 2018

Abolishment of fear memory-disruptive effects REM sleep deprivation by harmane.

Biomed Pharmacother 2019 Jan 14;109:1563-1568. Epub 2018 Nov 14.

Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran; Iranian National Center for Addiction Studies, Tehran University of Medical Sciences, Tehran, Iran; Institute for Cognitive Science Studies (ICSS), Tehran, Iran. Electronic address:

Harmane, as a neuromodulator, implicates in the learning and memory processes. However, rapid eye movement (REM) sleep deprivation negatively affects these processes. Here, we investigated the effects of harmane (2. Read More

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January 2019

Nocturnal ventricular repolarization lability predicts cardiovascular mortality in the Sleep Heart Health Study.

Am J Physiol Heart Circ Physiol 2018 Dec 14. Epub 2018 Dec 14.

Institut für Biomedizinische Technik, TU Dresden.

Background-The objective of this study was to quantify repolarization lability and its association with sex, sleep stage and cardiovascular mortality. Methods-We analyzed polysomnographic recordings of 2,263 participants enrolled in the Sleep heart health study (SHHS-2). Beat-to-beat QT interval variability (QTV) was quantified for consecutive epochs of 5 minutes according to the dominant sleep stage (AWAKE, NREM2, NREM3, REM). Read More

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December 2018

[Effects of sleep body posture on subjective sleepiness in patients with OSAHS].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Sep;32(18):1418-1421

Department of Otorhinolaryngology,the Affiliated Huaian No.1 People's Hospital of Nanjing Medical University,Huaian, 223300, China.

To observe the effects of sleep body posture on subjective sleepiness in patients with OSAHS. We assessed the sleeping body position, the sleep structure, position specific AHI and the Epworth Sleepiness Scale (ESS) in a total of 90 patients with OSAHS. The patients were grouped according to AHI: mild OSAHS (5≤AHI<15), moderate (15≤AHI<30) and severe (AHI≥30). Read More

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September 2018

Simultaneous Adsorption and Electrochemical Reduction of N-Nitrosodimethylamine using Carbon-TiO Composite Reactive Electrochemical Membranes.

Environ Sci Technol 2018 Dec 14. Epub 2018 Dec 14.

This study focused on synthesis and characterization of Ti4O7 reactive electrochemical membranes (REMs) amended with powder activated carbon (PAC) or multi-walled carbon nanotubes (MWCNTs). These composite REMs were evaluated for simultaneous adsorption and electrochemical reduction of N-Nitrosodimethylamine (NDMA). The carbon-Ti4O7 composite REMs had high electrical conductivities (1832 to 2991 S m-1), where carbon and Ti4O7 were in direct electrical contact. Read More

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December 2018

Automatic sleep stages classification using respiratory, heart rate and movement signals.

Physiol Meas 2018 Dec 4. Epub 2018 Dec 4.

Hochschule Konstanz Technik Wirtschaft und Gestaltung, Konstanz, Baden-Württemberg, GERMANY.

Objective: This paper presents an algorithm for non-invasive sleep stage identification using respiratory, heart rate and movement signals. The algorithm is part of a system suitable for long-term monitoring in a home environment, which should support experts analysing sleep.

Approach: As there is a strong correlation between bio-vital signals and sleep stages, multinomial logistic regression was chosen for categorical distribution of sleep stages. Read More

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December 2018

Deep learning in the cross-time-frequency domain for sleep staging from a single lead electrocardiogram.

Physiol Meas 2018 Nov 23. Epub 2018 Nov 23.

Department of Biomedical Informatics, Emory University, 36 Eagle Row, #571, MS 2045-001-1AC, Atlanta, GA 30322, Atlanta, Georgia, UNITED STATES.

Objective: This study classifies sleep stages from a single lead electrocardiogram (ECG) using beat detection, cardiorespiratory coupling in the time-frequency domain and a deep convolutional neural network (CNN). Approach: An ECG-derived respiration (EDR) signal and synchronous beat-to-beat heart rate variability (HRV) time series were derived from the ECG using previously described robust algorithms. A measure of cardiorespiratory coupling (CRC) was extracted by calculating the coherence and cross-spectrogram of the EDR and HRV signal in five-minute windows. Read More

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November 2018

Response to "prospective memory impairment in idiopathic REM sleep behavior disorder".

Authors:
Xudong Li

Sleep Med 2018 Oct 9. Epub 2018 Oct 9.

Department of Neurology, China-Japan Friendship Hospital, Yinghua East Road, Chaoyang District, Beijing, 100029, China. Electronic address:

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October 2018

Altered sleep architecture, rapid eye movement (REM) sleep, and neural oscillation in a mouse model of human chromosome 16p11.2 microdeletion.

Sleep 2018 Dec 12. Epub 2018 Dec 12.

Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, University of Southern California, Los Angeles, CA.

Sleep abnormalities are common among children with neurodevelopmental disorders. The human chr16p11.2 microdeletion is associated with a range of neurological and neurobehavioral abnormalities. Read More

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December 2018
3 Reads

High-Order Visual Processing, Visual Symptoms, and Visual Hallucinations: A Possible Symptomatic Progression of Parkinson's Disease.

Front Neurol 2018 27;9:999. Epub 2018 Nov 27.

Department of Neurology, Mayo Clinic, Rochester, MN, United States.

To determine whether Parkinson disease (PD) patients with (VH) have different clinical characteristics and gray-matter volume than those with visual misperceptions (VM) or other visual symptoms (OvS). The spectrum of visual complaints in PD is broad and complex. We conducted a retrospective chart review of 525 PD patients to identify the frequency of visual symptoms and the association with clinical and radiological features. Read More

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November 2018

Spectral Properties of Brain Activity Under Two Anesthetics and Their Potential for Inducing Natural Sleep in Birds.

Front Neurosci 2018 27;12:881. Epub 2018 Nov 27.

School of Life Sciences, La Trobe University, Melbourne, VIC, Australia.

Both mammals and birds exhibit two sleep states, slow wave sleep (SWS) and rapid eye movement (REM) sleep. Studying certain aspects of sleep-related electrophysiology in freely behaving animals can present numerous methodological constraints, particularly when even fine body movements interfere with electrophysiological signals. Interestingly, under light general anesthesia, mammals and birds also exhibit slow waves similar to those observed during natural SWS. Read More

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November 2018

BLINK: A package for the next level of genome-wide association studies with both individuals and markers in the millions.

Gigascience 2018 Dec 11. Epub 2018 Dec 11.

Department of Crop and Soil Sciences, Washington State University, 1170 NE stadium Way Pullman, Washington State 99164-6420, United States of America.

Big datasets, accumulated from biomedical and agronomic studies, provide the potential to identify genes controlling complex human diseases and agriculturally important traits through genome-wide association studies (GWAS). However, big datasets also lead to extreme computational challenges, especially when sophisticated statistical models are employed to simultaneously reduce false positives and false negatives. The newly developed Fixed and random model Circulating Probability Unification (FarmCPU) method uses a bin method under the assumption that Quantitative Trait Nucleotides (QTNs) are evenly distributed throughout the genome. Read More

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December 2018

Direct Activation of G-protein-gated Inward Rectifying K+ Channels (GIRK) Promotes Non-Rapid Eye Movement Sleep.

Sleep 2018 Dec 11. Epub 2018 Dec 11.

AfaSci Research Laboratories, Redwood City, California, USA.

Study Objectives: A major challenge in treating insomnia is to find effective medicines with fewer side effects. Activation of G-protein-gated inward rectifying K+ channels (GIRKs) by GABAB agonists baclofen or γ-hydroxybutyric acid (GHB) promotes non-rapid eye movement (NREM) sleep and consolidates sleep. However, baclofen has poor brain penetration, GHB possesses abuse liability, and in rodents both drugs cause spike-wave discharges (SWDs), an absence seizure activity. Read More

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December 2018

A phenotype of increased sleepiness in a mouse model of pulmonary hypertension and right ventricular hypertrophy.

PLoS One 2018 7;13(12):e0208540. Epub 2018 Dec 7.

Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States of America.

The relationship between cardiovascular disease and abnormalities in sleep architecture is complex and bi-directional. Sleep disordered breathing (SDB) often confounds human studies examining sleep in the setting of heart failure, and the independent impact of isolated right or left heart failure on sleep is difficult to assess. We utilized an animal model of right heart failure using pulmonary artery banding (PAB) in mice to examine the causal effect of right heart failure on sleep architecture. Read More

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December 2018

Obstructive events in children with Prader-Willi syndrome occur predominantly during rapid eye movement sleep.

Sleep Med 2018 Oct 28;54:43-47. Epub 2018 Oct 28.

Division of Pediatric Pulmonology and Sleep Disorders Laboratory, First Department of Pediatrics, National and Kapodistrian University of Athens School of Medicine and Aghia Sophia Children's Hospital, Athens, Greece. Electronic address:

Objective: Children with Prader-Willi syndrome (PWS) have a high prevalence of obstructive sleep apnea syndrome (OSAS). In most typically developing children with OSAS, more obstructive apneas and hypopneas occur during rapid eye movement (REM) than during non-REM (NREM) sleep. It was hypothesized that patients with PWS are even more prone to obstructive events in REM sleep than otherwise healthy subjects with OSAS. Read More

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October 2018

[Evolution of surgical indications in upper limb functional surgery for tetraplegic patients: Retrospective study of 428 procedures].

Ann Chir Plast Esthet 2018 Dec 7. Epub 2018 Dec 7.

Service de chirurgie plastique reconstructrice et esthétique, hôpital Saint-Louis, 1, avenue Claude-Vellefaux, 75010 Paris, France.

Introduction: Regarding surgical strategy for upper limb functional rehabilitation in patients with traumatic tetraplegia, there are few publications and the case series are quite small.

Patients And Method: We reviewed all traumatic quadriplegic patients, operated one by one surgeon, professor Marc Revol, for functional surgery of the upper limb in the same department from 1989 to 2018. For each patient, we recorded their gender, their group according to the international classification, their age at the time of the first surgical procedure, the length of time between the accident and the first surgery and between two procedures, the average duration of the whole surgical program, and the surgical technique used for the elbow, the wrist, the long fingers and the thumb. Read More

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December 2018

Prediction error connectivity: A new method for EEG state analysis.

Neuroimage 2018 Nov 30. Epub 2018 Nov 30.

Epilepsy Unit - Neurology Dept. Hospital del Mar - Parc de Salut Mar, Barcelona, Spain; IMIM - Hospital del Mar Medical Research Institute, Barcelona, Spain.

Several models have been proposed to explain brain regional and interregional communication, the majority of them using methods that tap the frequency domain, like spectral coherence. Considering brain interareal communication as binary interactions, we describe a novel method devised to predict dynamics and thus highlight abrupt changes marked by unpredictability. Based on a variable-order Markov model algorithm developed in-house for data compression, the prediction error connectivity (PEC) estimates network transitions by calculating error matrices (EMs). Read More

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November 2018
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Bottom-up gamma and bipolar disorder, clinical and neuroepigenetic implications.

Bipolar Disord 2018 Dec 1. Epub 2018 Dec 1.

Center for Translational Neuroscience, University of Arkansas for Medical Sciences, Little Rock, AR, USA.

Objectives: This limited review examines the role of the reticular activating system (RAS), especially the pedunculopontine nucleus (PPN), one site of origin of bottom-up gamma, in the symptoms of bipolar disorder (BD).

Methods: The expression of neuronal calcium sensor protein 1 (NCS-1) in the brains of BD patients is increased. It has recently been found that all PPN neurons manifest intrinsic membrane beta/gamma frequency oscillations mediated by high threshold calcium channels, suggesting that it is one source of bottom-up gamma. Read More

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December 2018
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To eat or to sleep: That is a lateral hypothalamic question.

Neuropharmacology 2018 Nov 29. Epub 2018 Nov 29.

Department of Neurology, Beth Israel Deaconess Medical Center, Division of Sleep Medicine, Harvard Medical School, Boston, MA, 02215, USA.

The lateral hypothalamus (LH) is a functionally and anatomically complex brain region that is involved in the regulation of many behavioral and physiological processes including feeding, arousal, energy balance, stress, reward and motivated behaviors, pain perception, body temperature regulation, digestive functions and blood pressure. Despite noteworthy experimental efforts over the past decades, the circuit, cellular and synaptic bases by which these different processes are regulated by the LH remains incompletely understood. This knowledge gap links in large part to the high cellular heterogeneity of the LH. Read More

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November 2018
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The risk of neurodegeneration in REM sleep behavior disorder: A systematic review and meta-analysis of longitudinal studies.

Sleep Med Rev 2018 Nov 8;43:37-46. Epub 2018 Nov 8.

"Vita-Salute" San Raffaele University, Milan, Italy; IRCCS San Raffaele Scientific Institute, Department of Clinical Neurosciences, Neurology - Sleep Disorders Centre, Milan, Italy. Electronic address:

Several studies report an association between REM Sleep Behavior Disorder (RBD) and neurodegenerative diseases, in particular synucleinopathies. Interestingly, the onset of RBD precedes the development of neurodegeneration by several years. This review and meta-analysis aims to establish the rate of conversion of RBD into neurodegenerative diseases. Read More

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November 2018
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Corollary discharge in precerebellar nuclei of sleeping infant rats.

Elife 2018 12 5;7. Epub 2018 Dec 5.

Department of Psychological and Brain Sciences, University of Iowa, Iowa, United States.

In week-old rats, somatosensory input arises predominantly from external stimuli or from sensory feedback (reafference) associated with myoclonic twitches during active sleep. A previous study suggested that the brainstem motor structures that produce twitches also send motor copies (or corollary discharge, CD) to the cerebellum. We tested this possibility by recording from two precerebellar nuclei-the inferior olive (IO) and lateral reticular nucleus (LRN). Read More

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December 2018
2 Reads

Phenoconversion from Idiopathic Rapid Eye Movement Sleep Behavior Disorder to Lewy Body Disease.

Mov Disord Clin Pract 2018 Sep-Oct;5(5):506-511. Epub 2018 Oct 3.

Center of Sleep Medicine Dokkyo Medical University Hospital Tochigi Japan.

Background: The conversion rate and estimated risk of neurodegenerative diseases vary with idiopathic rapid eye movement sleep behavior disorder (IRBD).

Methods: This retrospective cohort study examined 273 patients (213 men, 60 women) with polysomnographic-confirmed IRBD (192 and 81 patients in the Sleep Center [SC] cohort and Neurological Center [NC] cohort, respectively) who were followed longitudinally. The date of diagnosis was determined as the onset of an overt neurological syndrome. Read More

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October 2018
5 Reads

Sleep Quality and Levodopa Intestinal Gel Infusion in Parkinson's Disease: A Pilot Study.

Parkinsons Dis 2018 1;2018:8691495. Epub 2018 Nov 1.

Movement Disorders Unit, Department of Neurology, Hospital Universitari Vall D'Hebron, Neurodegenerative Diseases Research Group-Vall D'Hebron Research Institute, Universitat Autònoma de Barcelona, Barcelona, Spain.

Background: Sleep problems in patients with advanced Parkinson's disease (PD) have a deleterious impact on quality of life.

Objective: To assess the effect of levodopa-carbidopa intestinal gel (LCIG) infusion on sleep quality in advanced PD patients.

Methods: Seven patients participated in a prospective pilot study. Read More

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November 2018
4 Reads

Heart rate variability changes in major depressive disorder during sleep: Fractal index correlates with BDI score during REM sleep.

Psychiatry Res 2018 Nov 12;271:291-298. Epub 2018 Nov 12.

Department of Biomedical Engineering, College of Medicine, Seoul National University, Seoul 03080, Republic of Korea; Institute of Medical and Biological Engineering, Medical Research Center, Seoul National University, Seoul 03080, Republic of Korea. Electronic address:

We investigated the relationship between autonomic nervous system activity during each sleep stage and the severity of depressive symptoms in patients with major depressive disorder (MDD) and healthy control subjects. Thirty patients with MDD and thirty healthy control subjects matched for sex, age, and body mass index completed standard overnight polysomnography. Depression severity was assessed using the Beck Depression Inventory (BDI). Read More

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November 2018
6 Reads

A preliminary investigation into hearing aid fitting based on automated real-ear measurements integrated in the fitting software: test-retest reliability, matching accuracy and perceptual outcomes.

Int J Audiol 2018 Dec 4:1-9. Epub 2018 Dec 4.

a KU Leuven , Department of Neurosciences , Leuven , Belgium.

The recent integration of automated real-ear measurements (REM) in the fitting software facilitates the hearing aid fitting process. Such a fitting strategy, TargetMatch (TM), was evaluated. Test-retest reliability and matching accuracy were quantified, and compared to a REM-based fitting with manual adjustment. Read More

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December 2018

Validity and interpretability of the QuickDASH in the assessment of hand disability in rheumatoid arthritis.

Rheumatol Int 2018 Dec 3. Epub 2018 Dec 3.

Rheumatological Clinic, Ospedale "Carlo Urbani", Università Politecnica delle Marche, Via Aldo Moro, 25, Jesi, 60035, Ancona, Italy.

Objective of this study is to evaluate the construct validity and the interpretability of the shortened Disability of Arm, Shoulder and Hand Questionnaire (QuickDASH) in the assessment of rheumatoid arthritis (RA) hand disability. Consecutive RA patients were assessed through the QuickDASH and other function and disease activity indices, respectively, the Health Assessment Questionnaire-Disability Index (HAQ-DI) and the Recent-Onset Arthritis Disability questionnaire (ROAD). For each patient were evaluated the tender and swollen 28-joints counts. Read More

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December 2018

[Long-term outcome prediction in patients with stroke].

Zh Nevrol Psikhiatr Im S S Korsakova 2018 ;118(9. Vyp. 2):37-41

Research Institute of Cerebrovascular Pathology and Stroke of Pirogov Russian National Research Medical University, Moscow, Russia.

Aim: To create a model to predict long-term stroke outcome using polysomnographic parameters.

Material And Methods: Authors prospectively enrolled 56 acute stroke patients. All subjects underwent clinical evaluation and polysomnographic study. Read More

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January 2018
3 Reads

The first night effect in multiple sclerosis patients undergoing home-based polysomnography.

Nat Sci Sleep 2018 26;10:337-344. Epub 2018 Oct 26.

NeuroCure Clinical Research Center, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.

Background: The first night effect (FNE) is a polysomnography (PSG) habituation effect in the first of several consecutive in-laboratory PSGs (I-PSGs). The FNE is caused by the discomfort provoked by electrodes and cables and the exposure to an unfamiliar environment. A reverse FNE (RFNE) with an improved sleep in the first night is characteristic of insomnia, presumably because the video PSG in the sleep laboratory leads to a decrease in the negatively toned cognitive activity. Read More

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October 2018
1 Read

Heart Rate Variability During Nocturnal Sleep and Daytime Naps in Patients With Narcolepsy Type 1 and Type 2.

J Clin Neurophysiol 2018 Nov 27. Epub 2018 Nov 27.

Departments of Neurology and.

Purpose: Heart rate variability is a noninvasive measure of autonomic function. The aim of this study was to determine the risk of cardiovascular autonomic dysfunction during sleep in patients with narcolepsy. The effect of daytime napping was also examined in patients with narcolepsy type 1 and type 2. Read More

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November 2018
1 Read

Examining therapist effects in relation to clients' race-ethnicity and gender: An intersectionality approach.

J Couns Psychol 2018 Nov 29. Epub 2018 Nov 29.

University Counseling Services.

Women and Men of Color experience racism in unique and complex ways, just as White Women and Women of Color experience unique forms of sexism (i.e., gendered racism). Read More

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November 2018

Dosimetry, biodistribution, and safety of flurpiridaz F 18 in healthy subjects undergoing rest and exercise or pharmacological stress PET myocardial perfusion imaging.

J Nucl Cardiol 2018 Nov 28. Epub 2018 Nov 28.

Lantheus Medical Imaging, Billerica, MA, USA.

The objectives of this study were to evaluate radiation dosimetry, biodistribution, human safety, and tolerability of F-labeled flurpiridaz (Flurpiridaz) in normal subjects undergoing rest and separate-day exercise or adenosine pharmacological stress PET imaging.

Methods: 12 normal subjects were injected with 58.5 to 121 MBq (1. Read More

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November 2018
2 Reads

Silencing of Hypoglossal Motoneurons Leads to Sleep Disordered Breathing in Lean Mice.

Front Neurol 2018 14;9:962. Epub 2018 Nov 14.

Division of Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, United States.

Obstructive Sleep Apnea (OSA) is a prevalent condition and a major cause of morbidity and mortality in Western Society. The loss of motor input to the tongue and specifically to the genioglossus muscle during sleep is associated with pharyngeal collapsibility and the development of OSA. We applied a novel chemogenetic method to develop a mouse model of sleep disordered breathing Our goal was to reversibly silence neuromotor input to the genioglossal muscle using an adeno-associated viral vector carrying inhibitory designer receptors exclusively activated by designer drugs AAV5-hM4Di-mCherry (DREADD), which was delivered bilaterally to the hypoglossal nucleus in fifteen C57BL/6J mice. Read More

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November 2018
2 Reads

Excessive Daytime Sleepiness and REM Sleep Behavior Disorders in Parkinson's Disease: A Narrative Review on Early Intervention With Implications to Neuroprotection.

Front Neurol 2018 14;9:961. Epub 2018 Nov 14.

The Norwegian Centre for Movement Disorders, Stavanger University Hospital, Stavanger, Norway.

Sleep contributes to the consolidation of our memory and facilitates learning. Short term sleep deprivation temporarily reduces mnestic capacity, whereas long lasting sleep deprivation is associated with structural changes in the hippocampus and cortical areas. However, it is unknown whether early intervention and treatment of sleep disorders could have a neuroprotective effect. Read More

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November 2018
1 Read

Insight and Dissociation in Lucid Dreaming and Psychosis.

Front Psychol 2018 12;9:2164. Epub 2018 Nov 12.

Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States.

Dreams and psychosis share several important features regarding symptoms and underlying neurobiology, which is helpful in constructing a testable model of, for example, schizophrenia and delirium. The purpose of the present communication is to discuss two major concepts in dreaming and psychosis that have received much attention in the recent literature: insight and dissociation. Both phenomena are considered functions of higher order consciousness because they involve metacognition in the form of reflective thought and attempted control of negative emotional impact. Read More

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November 2018
1 Read

Clinical benefit of using a multifractional Er:YAG laser combined with a spatially modulated ablative (SMA) module for the treatment of striae distensae: A prospective pilot study in 20 patients.

Lasers Surg Med 2018 Nov 27. Epub 2018 Nov 27.

Department of Plastic, Reconstructive and Maxillo facial Surgery, Hopital Henri Mondor, Creteil, 94010, France.

Background And Objective: Striae distensae (SD) are cutaneous lesions that often occur on the breasts, abdomen, hips, and thighs. The aim of this study is to evaluate the effectiveness of a new technique using a non-invasive Er:YAG laser combined with Spatially Modulated Ablation (SMA) module for the treatment of SD.

Study Design/materials And Methods: This prospective pilot clinical study included 20 patients with skin phototypes I to IV who are affected by SD. Read More

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November 2018
5 Reads

Effects of Natural Between-Days Variation in Sleep on Elite Athletes' Psychomotor Vigilance and Sport-Specific Measures of Performance.

J Sports Sci Med 2018 Dec 20;17(4):515-524. Epub 2018 Nov 20.

Behavioural Science Institute, Radboud University, Nijmegen, The Netherlands.

Performance capacity in athletes depends on the ability to recover from past exercise. While evidence suggests that athletic performance decreases following (partial) sleep deprivation and increases following sleep extension, it is unclear to which extent natural variation in sleep impacts performance. Sleep quantity and, for the first time, sleep stages were assessed among 98 elite athletes on three non-consecutive nights within a 7-day monitoring period, along with performance tests that were taken on standardized times each following morning. Read More

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December 2018
3 Reads

Towards a Complete Taxonomy of Resting State Networks Across Wakefulness and Sleep: An Assessment of Spatially Distinct Resting State Networks Using Independent Component Analysis.

Sleep 2018 Nov 26. Epub 2018 Nov 26.

Brain & Mind Institute, Western University, London, Canada (institution where the research was performed).

Resting state network (RSN) functional connectivity (FC) has been investigated under a wealth of different healthy and compromised conditions. However such investigations are often dependent on the defined spatial boundaries and nodes of so-called canonical RSNs, themselves the product of extensive deliberations over distinctions between functional magnetic resonance imaging (fMRI) noise and neural signal, specifically in the context of the healthy waking state. However, a similar unbiased cataloguing of noise and networks remains to be done in other states, particularly sleep, a healthy alternate mode of the brain that supports distinct operations from wakefulness, such as dreaming and memory consolidation. Read More

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November 2018
1 Read

Validation of an automated sleep spindle detection method for mouse EEG.

Sleep 2018 Nov 17. Epub 2018 Nov 17.

VA Boston Healthcare System and Harvard Medical School Department of Psychiatry, West Roxbury, MA, USA.

Study Objectives: Sleep spindles are abnormal in several neuropsychiatric conditions and have been implicated in associated cognitive symptoms. Accordingly, there is growing interest in elucidating the pathophysiology behind spindle abnormalities using rodent models of such disorders. However, whether sleep spindles can reliably be detected in mouse electroencephalography (EEG) is controversial necessitating careful validation of spindle detection and analysis techniques. Read More

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November 2018
5 Reads

Heart Rate Variability Rebound Following Exposure to Persistent and Repetitive Sleep Restriction.

Sleep 2018 Nov 17. Epub 2018 Nov 17.

Department of Neurology, Beth Israel Deaconess Medical Center/Harvard Medical School.

While it is well established that slow wave sleep electroencephalography (EEG) rebounds following sleep deprivation, very little research has investigated autonomic nervous system recovery. We examined heart rate variability (HRV) and cardiovagal baroreflex sensitivity (BRS) during 4 blocks of repetitive sleep restriction and sequential nights of recovery sleep. Twenty-one healthy participants completed the 22-day in-hospital protocol. Read More

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November 2018
2 Reads

Sleep-related Eating Disorder in a Patient with Parkinson's Disease.

Cureus 2018 Sep 22;10(9):e3345. Epub 2018 Sep 22.

Neurology, University of Missouri, Columbia, USA.

Sleep disorders constitute a major aspect of the non-motor symptoms of Parkinson's disease (PD). Rapid eye movement (REM) behavior disorders are the most frequently experienced parasomnias in patients with PD. Non-REM sleep disorders like confusional arousals, sleep terrors, sleepwalking, and sleep-related eating disorder (SRED) are also associated with PD. Read More

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September 2018
3 Reads

Validation of a new data-driven automated algorithm for muscular activity detection in REM sleep behavior disorder.

J Neurosci Methods 2018 Nov 20;312:53-64. Epub 2018 Nov 20.

Department of Electrical Engineering, Technical University of Denmark, Kgs. Lyngby, Denmark.

Background: Documentation of REM sleep without atonia is fundamental for REM sleep behavior disorder (RBD) diagnosis. The automated REM atonia index (RAI), Frandsen index (FRI) and Kempfner index (KEI) were proposed for this, but achieved moderate performances.

New Method: Using sleep data from 27 healthy controls (C), 29 RBD patients and 36 patients with periodic limb movement disorder (PLMD), we developed and validated a new automated data-driven method for identifying movements in chin and tibialis electromyographic (EMG) signals. Read More

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November 2018
1 Read

Obstructive sleep apnea during REM sleep and daytime cerebral functioning: A regional cerebral blood flow study using high-resolution SPECT.

J Cereb Blood Flow Metab 2018 Nov 22:271678X18814106. Epub 2018 Nov 22.

1 Center for Advanced Research in Sleep Medicine, Hôpital du Sacré-Coeur, Montreal, Canada.

Obstructive sleep apnea (OSA) predominantly during rapid eye movement (REM) sleep may have impacts on brain health, even in milder OSA cases. Here, we evaluated whether REM sleep OSA is associated with abnormal daytime cerebral functioning using high-resolution single-photon emission computed tomography (SPECT). We tested 96 subjects (25 F, age: 65. Read More

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November 2018
7 Reads

Training on an Appetitive (Delay)-Conditioning Task Enhances Oscillatory Waves During Sleep in the Cortical and Amygdalar Network.

Front Behav Neurosci 2018 7;12:260. Epub 2018 Nov 7.

School of Life Sciences, Jawaharlal Nehru University, New Delhi, India.

Oscillating waves during sleep play an essential role in memory consolidation. The cortical slow wave activity (SWA) and sigma waves during NREM sleep and theta waves during REM sleep increase after a variety of memory tasks including declarative, procedural and associative learning tasks. These oscillatory waves during sleep help to promote neural dialog between circuitries, which possibly plays a causal role in memory consolidation. Read More

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November 2018
2 Reads

Nasal high flow, but not supplemental O, reduces peripheral vascular sympathetic activity during sleep in COPD patients.

Int J Chron Obstruct Pulmon Dis 2018 2;13:3635-3643. Epub 2018 Nov 2.

Department of Medicine, Division of Pulmonary and Critical Care Medicine, Johns Hopkins School of Medicine, Baltimore, MD, USA,

Introduction: Patients with COPD have increased respiratory loads and altered blood gases, both of which affect vascular function and sympathetic activity. Sleep, particularly rapid eye movement (REM) sleep, is known to exacerbate hypoxia and respiratory loads. Therefore, we hypothesize that nasal high flow (NHF), which lowers ventilatory loads, reduces sympathetic activity during sleep and that this effect depends on COPD severity. Read More

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November 2018
4 Reads

Pharmacological analysis of dexmedetomidine hydrochloride in pediatric anesthesia during magnetic resonance imaging.

Pak J Pharm Sci 2018 Sep;31(5(Special)):2209-2214

Department of Anesthesiology, Qilu Hospital of Shandong University, Jinan, China.

Dexmendetomidine hydrochloride (DEX) is a new common adrenergic receptor agonist, which not only keeps children calm but also has analgesic effect. Dexmedetomidine hydrochloride will enable children to maintain the natural non-REM sleep, which can be stimulated sedation or language arousal. The aim of this study is to observe the sedative effect and adverse drug reactions of dexmedetomidine hydrochloride injection and propofol injection in MRI examination. Read More

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September 2018
1 Read