1,555 results match your criteria Pyogenic Hepatic Abscesses


Corneal Endotheliitis Associated with a Methicillin Resistant Pyogenic Liver Abscess.

J Clin Exp Immunol 2020 13;5(3):120-122. Epub 2020 May 13.

Department of Ophthalmology and Visual Sciences, University of Maryland School of Medicine, Baltimore, MD.

Endotheliitis is the inflammation of the corneal endothelium resulting in edema and subsequent loss of vision. Bacterial causes of corneal inflammation primarily of the epithelium with subsequent, secondary involvement of the endothelium have previously been described. Notably, however, there are no reports of isolated endotheliitis related to a bacterial pathogen. Read More

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http://dx.doi.org/10.33140/jcei.05.03.03DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7319184PMC

Liver Abscess due to : A Clinical Rarity.

Case Rep Infect Dis 2020 2;2020:1572023. Epub 2020 Jun 2.

Department of Gastroenterology, All India Institute of Medical Sciences, Bhubaneswar-751019, Odisha, India.

We report a case of pyogenic liver abscess caused by a rare causative agent, . A 45-year-old man with underlying uncontrolled diabetes mellitus who had stopped taking his daily dose of insulin since the last 4 days, presented with pain in the abdominal area of one-day duration. Upon his admission to achieve diabetic control, a routine ultrasound examination of abdomen revealed incidentally, a large abscess in the left lobe of the liver with impending rupture. Read More

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http://dx.doi.org/10.1155/2020/1572023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288222PMC

Pyogenic Liver Abscesses Caused by Acute Appendicitis: Frequency and Diagnostic and Therapeutic Recommendations.

Surg Infect (Larchmt) 2020 Jun 17. Epub 2020 Jun 17.

Department of Anaesthesiology and Intensive Care Medicine, University Hospital of Tuebingen, Tuebingen, Germany.

Pyogenic liver abscesses (PLA) are caused by biliary diseases or hematogenous spreading of mostly intra-abdominal infections. Liver abscesses resulted in hematogenous spreading of infections via the portal vein, such as abscesses caused by acute appendicitis. Pyogenic liver abscesses associated with appendicitis have rarely been described in the literature, especially in adults. Read More

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http://dx.doi.org/10.1089/sur.2019.366DOI Listing

Clinical and computed tomography features of extended-spectrum β-lactamase-producing Klebsiella pneumoniae liver abscess.

BMC Infect Dis 2020 Jun 15;20(1):416. Epub 2020 Jun 15.

Department of Radiology, Shengjing Hospital of China Medical University, NO. 36, Sanhao Street, Heping District, Shenyang, 110004, China.

Background: Klebsiella pneumoniae (KP) is the primary pathogen associated with pyogenic liver abscesses (PLAs). Moreover, there has been an increase in the proportion of extended-spectrum beta-lactamase (ESBL)-producing KP. However, the clinical and computed tomography (CT) features of liver abscesses caused by ESBL-producing KP have not been separately described. Read More

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http://dx.doi.org/10.1186/s12879-020-05142-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7296744PMC

Delayed bleeding complication due to internal mammary artery injury after ultrasound-guided percutaneous catheter drainage for liver cyst infection.

Acute Med Surg 2020 Jan-Dec;7(1):e512. Epub 2020 Jun 9.

Department of Cardiology Tokyo Metropolitan Hiroo Hospital Tokyo Japan.

Background: Ultrasound-guided percutaneous catheter drainage (PCD) is widely accepted as a primary treatment for pyogenic liver abscess. Severe PCD-related complications have been reported; however, delayed bleeding complications due to internal mammary artery injury are unknown.

Case Presentation: An 84-year-old man undergoing hemodialysis owing to chronic kidney disease due to focal segmental glomerulosclerosis was admitted to our hospital for liver cyst infection. Read More

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http://dx.doi.org/10.1002/ams2.512DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7283991PMC

Acute Presentation of Simultaneous Liver Abscesses Caused by Streptococcus constellatus.

Cureus 2020 Jun 7;12(6):e8497. Epub 2020 Jun 7.

Internal Medicine, Columbia University College of Physicians and Surgeons at Harlem Hospital Center, New York, USA.

Simultaneous liver abscesses are rarely seen and reported. We are reporting a case of two simultaneous, complex liver abscesses in a patient who had no evidence of liver abscess on cross-sectional imaging close to three months prior to this presentation. These abscesses were 7-8 cm in size, large, and septated. Read More

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http://dx.doi.org/10.7759/cureus.8497DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7282354PMC

Pyogenic liver abscess in liver transplant recipient: A warning signal for the risk of recurrence and retransplantation.

Transpl Infect Dis 2020 Jun 9:e13360. Epub 2020 Jun 9.

Service de Médecine Interne, Hôpital Beaujon, Assistance Publique - Hôpitaux de Paris, Clichy, France.

Background: Pyogenic liver abscesses in liver transplant recipients (PLA-LTR) are a rare disease whose specificities compared with PLA in non-transplanted patients (PLA-C) are unknown.

Methods: A retrospective case-control study was conducted in a French academic hospital from January 1, 2010, to December 31, 2014.

Results: Among 176 patients diagnosed with PLA, 14 were LTR; each case was matched with 3 PLA-C controls by date of PLA diagnosis and pathophysiological mechanism of PLA. Read More

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http://dx.doi.org/10.1111/tid.13360DOI Listing

A case of hepatic hydatid cyst together with pyogenic liver abscess in a Nepali patient.

J Parasit Dis 2020 Jun 18;44(2):472-475. Epub 2020 Mar 18.

Área de Parasitología, Departamento de Agroquímica y Medio Ambiente, Universidad Miguel Hernández de Elche, Campus de Sant Joan, 03550 Sant Joan, Alicante Spain.

Hydatidic disease (echinococcosis) is a significant health problem in Nepal. In humans, mainly involves liver and commonly remains silent without symptoms or causing only mild pressure symptomatology. However, inadequate invasive medical procedures may cause the rupture of the cyst with serious complications, anaphylactic shock and death. Read More

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http://dx.doi.org/10.1007/s12639-020-01213-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244686PMC

[Clinical characteristics of patients with pyogenic liver abscess].

Zhonghua Nei Ke Za Zhi 2020 Jun;59(6):439-444

Department of Infectious Diseases, Huashan Hospital Affiliated to Fudan University, Shanghai 200040, China.

To summarize the clinical features of patients with pyogenic liver abscess(KP-PLA). Clinical data of 133 patients with pyogenic liver abscess(PLA) and positive results of blood or pus culture were retrospectively analyzed in Huashan Hospital Affiliated to Fudan University from 2009 to 2018. According to the culture results, patients were divided into KP-PLA group (=92) and non-KP-PLA group (=41). Read More

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http://dx.doi.org/10.3760/cma.j.cn112138-20190610-00403DOI Listing

Bacterial Superinfection of Amoebic Liver Abscess.

J Investig Med High Impact Case Rep 2020 Jan-Dec;8:2324709620926900

Icahn School of Medicine at Mount Sinai, Elmhurst Hospital Center, Elmhurst, NY, USA.

A 78-year-old male, originally from China, was brought to the hospital for weakness, urinary incontinence, confusion, and poor oral intake. He was started on empiric antibiotics, which were narrowed when blood cultures produced gram-negative bacteremia speciating to , sensitive to ceftriaxone. Computed tomography scan of the abdomen and pelvis demonstrated a large cystic region with air-fluid level in the left lobe of the liver. Read More

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http://dx.doi.org/10.1177/2324709620926900DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263103PMC

Detection of multiple hypervirulent Klebsiella pneumoniae strains in a New York City hospital through screening of virulence genes.

Clin Microbiol Infect 2020 May 24. Epub 2020 May 24.

Department of Pathology & Cell Biology, Columbia University Irving Medical Center, New York, NY, USA.

Objectives: The 'hypervirulent' variant of Klebsiella pneumoniae (hvKp) is a predominant cause of community-acquired pyogenic liver abscess in Asia, and is an emerging pathogen in Western countries. hvKp infections have demonstrated 'metastatic' dissemination in immunocompetent hosts, an unusual mode of infection associated with severe complications. Two cases alerted us to the possible presence of hvKp at our hospital, both involving elderly Hispanic males who presented with recurrent fever, bacteraemia, epigastric pain and liver abscesses/phlegmon, thus prompting an assessment of hvKp prevalence. Read More

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http://dx.doi.org/10.1016/j.cmi.2020.05.012DOI Listing

Applying Data Mining to Investigate Cancer Risk in Patients with Pyogenic Liver Abscess.

Healthcare (Basel) 2020 May 22;8(2). Epub 2020 May 22.

Department of Industrial Engineering & Enterprise Information, Tunghai University, Taichung 407, Taiwan.

Pyogenic liver abscess is usually a complication of biliary tract disease. Taiwan features among the countries with the highest incidence of colorectal cancer (CRC) and hepatocellular carcinoma (HCC). Few studies have investigated whether patients with pyogenic liver abscess (PLA) have higher incidence rates of CRC and HCC. Read More

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http://dx.doi.org/10.3390/healthcare8020141DOI Listing

Management of pyogenic liver abscess: a South Australian experience.

ANZ J Surg 2020 May 26. Epub 2020 May 26.

Microbiology and Infectious Diseases, Flinders Medical Centre, Adelaide, South Australia, Australia.

Background: There have been declining mortality rates associated with pyogenic liver abscess (PLA) in recent decades due to improvements in percutaneous drainage techniques, access to imaging and improvements in supportive care. The aim of this study was to analyse the aetiology, management and outcome of PLA at a tertiary hospital in Adelaide.

Methods: Data was collected retrospectively from 80 patients who were admitted with a PLA between 2011 and 2018. Read More

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http://dx.doi.org/10.1111/ans.15963DOI Listing

Gastrointestinal Origins of Pyogenic Liver Abscess.

Authors:
Oscar M P Jolobe

Am J Med 2020 05;133(5):e210

Manchester Medical Society, Manchester, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.amjmed.2019.10.011DOI Listing

Pyogenic Liver Abscess or Liver Cyst Infection after Colonoscopic Polypectomy.

Korean J Gastroenterol 2020 May;75(5):300-304

Department of Internal Medicine, Inje University Haeundae Paik Hospital, Inje University College of Medicine, Busan, Korea.

A pyogenic liver abscess (PLA) mostly occurs in association with biliary tract disease, but some PLAs have no apparent underlying cause, i.e., they are cryptogenic. Read More

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http://dx.doi.org/10.4166/kjg.2020.75.5.300DOI Listing

Pyogenic Liver Abscess Secondary to Sigmoid Diverticulitis: An Unusual Presentation.

Case Rep Gastroenterol 2020 Jan-Apr;14(1):165-171. Epub 2020 Apr 17.

Southmead Hospital, North Bristol Trust, Bristol, United Kingdom.

Pyogenic liver abscesses, despite being a rare complication of diverticulitis and inflammatory bowel disease, are potentially serious life-threatening pathologies. Diverticular diseases can lead to disruption of the colonic mucosal barrier and can serve as a route for bacterial infection via the portal venous system. This patient had such a delayed presentation due to his atypical symptoms; he developed large abscess formation, detected by computed tomography, eventually requiring an ultrasound-guided drain followed by a colonoscopy. Read More

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http://dx.doi.org/10.1159/000506932DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7204770PMC

Pyogenic and Amebic Infections of the Liver.

Gastroenterol Clin North Am 2020 Jun;49(2):361-377

Division of Gastroenterology, Hepatology Program, Washington University School of Medicine, 660 S. Euclid Avenue, St. Louis, MO 63110, USA. Electronic address:

Pyogenic liver abscesses are classified by the bacteria that have caused the abscess because this guides treatment and can point to the underlying cause. The most common cause is biliary disease. The diagnosis is made by imaging. Read More

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http://dx.doi.org/10.1016/j.gtc.2020.01.013DOI Listing

A unusual case of multifocal pyogenic abscess formation following ERCP procedure.

BMC Surg 2020 May 6;20(1):92. Epub 2020 May 6.

Department of Surgery A, Galilee Medical Center, Nahariya, Israel.

Background: Endoscopic retrograde cholangiopancreatography (ERCP) is essential for managing biliary and pancreatic disorders. Infection is the most morbid complication of ERCP and among the most common causes of ERCP-related death.

Case Presentation: A 69-year-old man presented with right upper quadrant abdominal pain, obstructive jaundice and abnormal liver function tests. Read More

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http://dx.doi.org/10.1186/s12893-020-00759-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7203808PMC

Intracavitary contrast-enhanced ultrasound in ultrasound-guided percutaneous management of abdominal fluid collections/abscesses by a single clinician: an example of point-of-care ultrasound.

J Ultrasound 2020 Jun 2;23(2):175-181. Epub 2020 May 2.

Interventional Ultrasound Unit, Pineta Grande Hospital, SS Domitiana, KM 30,00, 81030, Castel Volturno, CE, Italy.

Purpose: To assess the role of intracavitary contrast-enhanced ultrasound (IC-CEUS) as a focused ultrasound (US) examination aimed at supporting a single physician in the management of interventional procedures for abdominal fluid collections/abscesses.

Methods: In 43 patients (27 M/16 F, median age 68 years, range 35-91), a single physician performed catheter drainage (42) or needle aspiration (3) for the following: 14 infected abdominal fluid collections, 11 non-infected abdominal fluid collections, 9 pyogenic liver abscesses, 8 gallbladder empyema, and 3 infected pancreatic fluid collections. IC-CEUS (0. Read More

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http://dx.doi.org/10.1007/s40477-020-00467-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242574PMC

Unusual Liver Mass in an Immunocompetent Adult: A Case Report and Literature Review.

Cureus 2020 Mar 22;12(3):e7361. Epub 2020 Mar 22.

Nephrology, Marshall University, Joan C Edwards School of Medicine, Huntington, USA.

A hepatic abscess is a rare disease, especially in developed countries, and usually results from microbial contamination of liver parenchyma via an arterial or portal system or from a direct spread by contiguity. Pyogenic liver abscesses (PLA) are polymicrobial with Staphylococcus aureus accounting for less than 10% of the cases and methicillin-resistant Staphylococcus aureus (MRSA) accounting for even fewer. Colonic and hepatobiliary pathologies are often associated with reported MRSA abscesses. Read More

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http://dx.doi.org/10.7759/cureus.7361DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7174860PMC

A febrile old man with xanthochromic hypoglycorrhachia.

Germs 2020 Mar 2;10(1):55-57. Epub 2020 Mar 2.

MD, Department of Medicine, Mackay Medical College, New Taipei City 252, Taiwan.

Introduction: Meningitis is a commonly seen disease in the daily practice of emergency departments. Cerebrospinal fluid (CSF) examination including Gram stain and culture are crucial for identifying between bacterial and viral meningitis and should be completed prior to antibiotic administration. Hypoglycorrhachia is one of the certain independent predictors of bacterial meningitis. Read More

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http://dx.doi.org/10.18683/germs.2020.1186DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7117881PMC

Gastric cancer and adenomatous colorectal polyp concomitant with pyogenic liver abscess and bacteremia.

Yeungnam Univ J Med 2020 Apr 10. Epub 2020 Apr 10.

Department of Internal Medicine, Yeungnam University College of Medicine, Daegu, Korea.

Synchronous gastric cancer and adenomatous colorectal polyp in patients with Klebsiella pneumoniae-induced pyogenic liver abscess (KP-PLA) and bacteremia is a rare presentation. A 58-year-old man with a 6-month history of diabetes mellitus (DM) presented with febrile sensation and dull abdominal pain in the right upper quadrant of the abdomen. Subsequent to laboratory test results and abdominal computed tomography findings, KP-PLA with bacteremia was diagnosed. Read More

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http://dx.doi.org/10.12701/yujm.2020.00094DOI Listing

Pediatric Liver Abscess: Trends in the Incidence, Etiology, and Outcomes Based on 20-Years of Experience at a Tertiary Center.

Front Pediatr 2020 24;8:111. Epub 2020 Mar 24.

Division of Pediatric Gastroenterology, Department of Pediatrics, Chang Gung Children's Medical Center, Chang Gung Memorial Hospital, Taoyuan City, Taiwan.

Liver abscess is an important but relatively rare disease in children. This study investigated the clinical characteristics of eligible patients at a referral tertiary center over the past two decades. A 20-year retrospective study (January 2000-December 2019) enrolled 38 children diagnosed with liver abscess. Read More

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http://dx.doi.org/10.3389/fped.2020.00111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7105830PMC

Screening of BHK-21 cellular proteins that interact with outer membrane protein 43K OMP of Fusobacterium necrophorum.

Anaerobe 2020 Jun 4;63:102184. Epub 2020 Mar 4.

Heilongjiang Provincial Key Laboratory of Prevention and Control of Bovine Diseases, College of Animal Science and Veterinary Medicine, Heilongjiang Bayi Agricultural University, Daqing, 163319, China. Electronic address:

Fusobacterium necrophorum is a Gram negative, spore-free, anaerobic bacterium that can cause pyogenic and necrotic infections in animals and humans. It is a major bovine pathogen and causes hepatic abscesses, foot rot, and necrotic laryngitis. The 43K OMP of F. Read More

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http://dx.doi.org/10.1016/j.anaerobe.2020.102184DOI Listing

'Giant' pyogenic liver abscess and .

BMJ Case Rep 2020 Mar 30;13(3). Epub 2020 Mar 30.

Department of Medicine, Laniado Hospital, Sanz Medical Centre, Netanya, Israel.

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http://dx.doi.org/10.1136/bcr-2019-234159DOI Listing

Hiccups : an uncommon presentation of pyogenic liver abscess.

Acta Gastroenterol Belg 2020 Jan-Mar;83(1):92-93

Department of Anesthesiology, Tri-Service General Hospital and National Defense Medical Center, Taipei, Taiwan, R.O.C.

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Multiple Pyogenic Liver Abscesses Mimicking Metastatic Disease on Computed Tomography.

Authors:
Esra Özgül

Cureus 2020 Feb 19;12(2):e7050. Epub 2020 Feb 19.

Radiology, Afyonkarahisar Health Science University, Afyonkarahisar, TUR.

Liver abscesses are divided into two main subgroups: pyogenic and nonpyogenic abscesses. Early diagnosis is important for appropriate treatment and to reduce the morbidity and mortality rates in liver abscesses. We report a case of multiple pyogenic liver abscesses mimicking liver metastases on multidetector computed tomography (MDCT). Read More

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http://dx.doi.org/10.7759/cureus.7050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086114PMC
February 2020

Outcomes of Gas-Forming Pyogenic Liver Abscess Are Comparable to Non-Gas-Forming Pyogenic Liver Abscess in the Era of Multi-Modal Care: A Propensity Score Matched Study.

Surg Infect (Larchmt) 2020 Mar 27. Epub 2020 Mar 27.

Department of General Surgery, Tan Tock Seng Hospital, Singapore.

Gas-forming pyogenic liver abscess (GFPLA) occurs in 7%-24% of all PLAs and has been associated traditionally with high mortality rates. Studies have suggested that the use of a proactive approach of prompt resuscitation, parenteral antibiotic agents, percutaneous drainage, and a dedicated multi-disciplinary team may improve clinical outcomes. Hence, we aim to investigate whether the clinical outcomes of PLA are determined by gas formation. Read More

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http://dx.doi.org/10.1089/sur.2019.278DOI Listing
March 2020
1.721 Impact Factor

pyogenic liver abscess presenting as chronic cough.

IDCases 2020 28;20:e00736. Epub 2020 Feb 28.

Department of Surgery, Saint Agnes Hospital, 900 S Caton Ave, Baltimore, MD 21229, United States.

is a Gram-negative rod belonging to the family and closely related to spp. It is commonly present in aquatic environments. Human infections caused by are being increasingly recognized. Read More

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http://dx.doi.org/10.1016/j.idcr.2020.e00736DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7082512PMC
February 2020

Incidence Trends, Comorbidities, and Outcomes of Pyogenic Liver Abscess Among Children: A Nationwide Population-based Analysis.

J Pediatr Gastroenterol Nutr 2020 Jul;71(1):106-111

Department of Pediatric Gastroenterology, Cleveland Clinic Children's hospital, Cleveland, OH.

Objectives: Population-based analysis of incidence, comorbid conditions, microbiological characteristics, and outcomes of pyogenic liver abscess (PLA) in children.

Methodology: Retrospective analysis of National Inpatient Sample (NIS) and Kids Inpatient database (KID) database from 2003 to 2014 and included patients between 1 and 20 years of age. Using ICD-9 codes, we identified all hospitalizations with PLA and compared them with 1 : 10 age- and gender-matched controls. Read More

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http://dx.doi.org/10.1097/MPG.0000000000002700DOI Listing

The aura of malignant tumor: Clinical analysis of malignant tumor-related pyogenic liver abscess.

Medicine (Baltimore) 2020 Feb;99(9):e19282

The Second Affiliated Hospital of Guangxi Medical University, PR China.

The global incidence of pyogenic liver abscess (PLA) is increasing, but related reports of malignant tumor-related PLA are infrequent. Potential malignant tumors of PLA have been reported, but there is no relevant predictive model for this subsection of patients.To explore the risk factors of malignant tumor-related PLA. Read More

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http://dx.doi.org/10.1097/MD.0000000000019282DOI Listing
February 2020

Tubercular granuloma mimicking pyogenic liver abscess.

J Family Med Prim Care 2020 Jan 28;9(1):424-427. Epub 2020 Jan 28.

Department of Medicine, AIIMS Rishikesh, Uttarakhand, India.

Hepatic Tuberculosis (TB) is extremely rare without miliary involvement in immunocompetent patients. Even in countries like India where TB is a major public health problem only few cases have been diagnosed and treated. We report a case of an immunocompetent patient who presented with undiagnosed pyrexia of 11 days, was initially diagnosed as pyogenic liver abscess, he did not responded to treatment and on liver biopsy was diagnosed as hepatic tuberculoma. Read More

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http://dx.doi.org/10.4103/jfmpc.jfmpc_630_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7014858PMC
January 2020

The Epidemiology of Hip Fracture among Subjects with Pyogenic Liver Abscess (PLA): A Nationwide Population-Based Study.

Biomed Res Int 2020 12;2020:5901962. Epub 2020 Feb 12.

School of Medicine, China Medical University, Taichung, Taiwan.

Pyogenic liver abscess (PLA) is a potentially fatal disease that can stimulate prominent systemic inflammation. Osteoporotic hip fracture is a major complication of systemic inflammation. This study tried to determine the epidemiology of hip fractures among PLA patients. Read More

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http://dx.doi.org/10.1155/2020/5901962DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037889PMC
February 2020

Effect of diabetes mellitus on short-term prognosis of 227 pyogenic liver abscess patients after hospitalization.

BMC Infect Dis 2020 Feb 17;20(1):145. Epub 2020 Feb 17.

National-Local Joint Engineering Research Center for Precision Surgery & Regenerative Medicine, Shaanxi Provincial Center for Regenerative Medicine and Surgical Engineering, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, Shaanxi Province, China.

Background: Pyogenic liver abscess (PLA) is an inflammatory disease with increasing incidence. When it occurs with diabetes mellitus (DM), the risk of recurrence and mortality may increase. However, the effect of DM on the short-term prognosis of PLA patients after hospitalization remained unknown. Read More

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http://dx.doi.org/10.1186/s12879-020-4855-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7027105PMC
February 2020

The increased recurrence rate of liver abscess caused by extended-spectrum β-lactamase-producing Klebsiella pneumoniae.

Eur J Clin Microbiol Infect Dis 2020 Jul 15;39(7):1315-1320. Epub 2020 Feb 15.

Department of Radiology, Shengjing Hospital of China Medical University, NO. 36, Sanhao Street, Heping District, Shenyang, 110004, China.

The pathogenic bacterium Klebsiella pneumoniae (KP) is the major causative agent of pyogenic liver abscess (PLA). But reports about the prognosis of KP-caused PLA (KPLA) are rare. This study aimed to ascertain the recurrence rate of KPLA after initial treatment and its contributing factors. Read More

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http://dx.doi.org/10.1007/s10096-020-03848-1DOI Listing

Beyond pyogenic liver abscess: a comprehensive review of liver infections in emergency settings.

Emerg Radiol 2020 Jun 12;27(3):307-320. Epub 2020 Feb 12.

Ohio State University Wexner Medical Center, Columbus, OH, USA.

Hepatobiliary infections are commonly encountered in emergency settings ranging from common pathology such as pyogenic abscess to relatively uncommon and rare etiologies. Since extensive literature is already available on imaging of more common bacterial infections, for the sake of focused discussion, this review will discuss radiological appearance of less commonly encountered hepatic infections of fungal, parasitic, viral, and tubercular etiologies. Epidemiological and clinical information remain extremely important for obtaining more accurate presumptive diagnosis. Read More

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http://dx.doi.org/10.1007/s10140-020-01757-6DOI Listing

Contrast-Enhanced Ultrasound Appearance of Hypervirulent Klebsiella pneumoniae Liver Abscesses.

J Ultrasound Med 2020 Jul 5;39(7):1447-1452. Epub 2020 Feb 5.

Department of Radiology, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.

There has been a paradigm shift with Klebsiella pneumoniae (KP) emerging as the most frequently isolated bacterium in pyogenic liver abscesses in immunocompetent patients. Colonization of this hypervirulent KP strain has led to community-acquired liver abscesses. Septic seeding to distant sites of the body has been recognized and is strongly associated with diabetes. Read More

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http://dx.doi.org/10.1002/jum.15235DOI Listing

Foodborne Klebsiella pneumoniae: Virulence Potential, Antibiotic Resistance, and Risks to Food Safety.

J Food Prot 2020 Jul;83(7):1096-1103

Environmental Health Institute, National Environment Agency, 11 Biopolis Way, #04-03/04, Helios Block, Singapore 138667, Singapore.

Abstract: Gastrointestinal carriage of Klebsiella pneumoniae is a predisposing factor for liver abscess in several Asian countries. To determine whether hypervirulent K. pneumoniae in the gut may be transmitted through food, we screened a range of raw and ready-to-eat retail food by culture and recovered K. Read More

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http://dx.doi.org/10.4315/JFP-19-520DOI Listing

A retrospective study of pyogenic liver abscess caused primarily by Klebsiella pneumoniae vs. non-Klebsiella pneumoniae: CT and clinical differentiation.

Abdom Radiol (NY) 2020 Jan 1. Epub 2020 Jan 1.

Department of Radiology, Gil Medical Center of Gachon University, Namdong-gu, Incheon, Republic of Korea.

Purpose: The incidence of Klebsiella pneumoniae pyogenic liver abscesses (KP-PLA) is increasing. However, its diagnosis and treatment are often delayed, leading to complications. In this study, we aimed to retrospectively compare computed tomographic (CT) features of KP-PLAs with those of abscesses caused by other bacterial pathogens (non-KP-PLAS) and to further identify prognostic factors for PLA. Read More

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http://dx.doi.org/10.1007/s00261-019-02389-2DOI Listing
January 2020

: a rare causative agent of pyogenic liver abscess.

BMJ Case Rep 2019 Dec 18;12(12). Epub 2019 Dec 18.

Division of Surgery, Christian Medical College and Hospital Vellore, Vellore, Tamil Nadu, India.

A 26-year-old man who was previously well presented to the emergency in septic shock. He had a preceding history of fever, right upper abdominal pain and jaundice. On examination, there was tenderness over the right hypochondrium and epigastrium, without features of generalised peritonitis. Read More

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http://dx.doi.org/10.1136/bcr-2019-229738DOI Listing
December 2019

Evaluation of clinical risk factors for developing pleural empyema secondary to liver abscess.

BMC Gastroenterol 2019 Dec 16;19(1):215. Epub 2019 Dec 16.

Department of Thoracic and Cardiovascular Surgery, Korea University College of Medicine, 73, Goryeodae-ro, Seongbuk-gu, Seoul, 02841, Republic of Korea.

Background: The aim of this study was to investigate the clinical manifestation and predictive risk factors of pleural empyema developing during treatment of the pyogenic liver abscess.

Methods: Medical records of patients with the liver abscess in our institution were reviewed retrospectively. Enrolled patients were classified into four groups; Group 1: patients without pleural effusion, Group 2: patients with pleural effusion and who were treated noninvasively, Group 3: patient with pleural effusion and who were treated with thoracentesis, and Group 4: patients with pleural effusion that developed into empyema. Read More

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http://dx.doi.org/10.1186/s12876-019-1128-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6915871PMC
December 2019

Liver abscess: diagnostic and management issues found in the low resource setting.

Br Med Bull 2019 12;132(1):45-52

Diagnostic Microbiology Development Program, 12152, Phnom-Penh, Cambodia.

Introduction: Liver abscesses are mainly caused by parasitic or bacterial infection and are an important cause of hospitalization in low-middle income countries (LMIC). The pathophysiology of abscesses is different depending on the etiology and requires different strategies for diagnosis and management. This paper discusses pathophysiology and epidemiology, the current diagnostic approach and its limitations and management of liver abscess in low resource settings. Read More

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http://dx.doi.org/10.1093/bmb/ldz032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6992887PMC
December 2019

Serum amyloid A levels in patients with liver diseases.

World J Gastroenterol 2019 Nov;25(43):6440-6450

Department of Gastroenterology and Hepatology, Zhongshan Hospital, Fudan University, Shanghai 200032, China.

Background: Serum amyloid A (SAA) is an acute phase protein mainly synthesized by the liver. SAA induces inflammatory phenotype and promotes cell proliferation in activated hepatic stellate cells, the major scar forming cells in the liver. However, few studies have reported on the serum levels of SAA in human liver disease and its clinical significance in various liver diseases. Read More

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http://dx.doi.org/10.3748/wjg.v25.i43.6440DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881510PMC
November 2019

Prognostic nomogram for the combination therapy of percutaneous catheter drainage and antibiotics in pyogenic liver abscess patients.

Abdom Radiol (NY) 2020 02;45(2):393-402

Department of Interventional Therapy, Inner Mongolia People's Hospital, 20 Zhaowuda Road, Huhhot, 010017, China.

Purpose: To identify the predictors for recovery of pyogenic liver abscess (PLA) patients treated with percutaneous catheter drainage (PCD) and antibiotics, and then develop an effective nomogram to predict the recovery time.

Materials And Methods: The retrospective study included consecutive PLA patients treated with PCD and antibiotics. We defined the overall recovery time (ORT) as the time from the PCD procedure to the time of clinical success or failure. Read More

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http://dx.doi.org/10.1007/s00261-019-02359-8DOI Listing
February 2020

​Treating pyogenic liver abscesses secondary to diverticulitis in a patient using immunosuppressants for Crohn's disease by performing a sigmoid colectomy.

BMJ Case Rep 2019 Dec 2;12(12). Epub 2019 Dec 2.

Department of Surgery, Alrijne Hospital Leiderdorp, Leiderdorp, The Netherlands.

Pyogenic liver abscess (PLA) formation is a rare complication of Crohn's disease (CD). As symptoms often mimic a CD exacerbation, diagnosis can be delayed leading to severe disease. The current case report describes a case of a patient with a history of CD that was admitted with multiple PLAs, which persisted despite percutaneous drainage combined with antibiotics. Read More

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http://dx.doi.org/10.1136/bcr-2019-231031DOI Listing
December 2019

Endoscopic Ultrasound-Guided Hepaticogastrostomy With Lumen-Apposing Metal Stent for Management of Pyogenic Liver Abscess.

ACG Case Rep J 2019 Sep 11;6(9):e00160. Epub 2019 Sep 11.

Montefiore Medical Center, Bronx, NY.

A 45-year-old man presented with abdominal pain, fever with chills, nonproductive cough, mild pleurisy, and anorexia. Computed tomography scan showed a heterogeneously enhancing mass in the left hepatic lobe with leukocytosis and elevated C-reactive protein. Interval growth of the lesion was noted on magnetic resonance imaging obtained several days after admission. Read More

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http://dx.doi.org/10.14309/crj.0000000000000160DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6831152PMC
September 2019

A prospective validation of Sepsis-3 guidelines in acute hepatobiliary sepsis: qSOFA lacks sensitivity and SIRS criteria lacks specificity (Cohort Study).

Int J Surg 2019 Dec 31;72:71-77. Epub 2019 Oct 31.

Department of General Surgery, Tan Tock Seng Hospital, Singapore, Singapore.

Background: Since its introduction in 2016, the Sepsis-3 guidelines, with emphasis on the quick Sequential Organ Failure Assessment (qSOFA) score, have generated much debate and controversy. It is recognised that the new definitions require validation in specific clinical settings and have yet to be universally adopted. We aim to validate new Sepsis-3 guidelines in acute hepatobiliary infection. Read More

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http://dx.doi.org/10.1016/j.ijsu.2019.10.022DOI Listing
December 2019

Hypervirulent Klebsiella pneumoniae - clinical and molecular perspectives.

J Intern Med 2020 Mar 21;287(3):283-300. Epub 2019 Nov 21.

Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA, USA.

Hypervirulent Klebsiella pneumoniae (hvKp) has emerged as a concerning global pathogen. hvKp is more virulent than classical K. pneumoniae (cKp) and capable of causing community-acquired infections, often in healthy individuals. Read More

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http://dx.doi.org/10.1111/joim.13007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057273PMC

Clinical, microbiological, and molecular epidemiological characteristics of -induced pyogenic liver abscess in southeastern China.

Antimicrob Resist Infect Control 2019 29;8:166. Epub 2019 Oct 29.

1Department of Clinical Laboratory, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325000 China.

Background: -induced pyogenic liver abscess (KP-PLA) has emerged as a life-threatening disease worldwide. However, to date, a limited number of scholars have attempted to systematically elucidate the characteristics of KP-PLA. The aim of the present study was to analyze clinical, microbiological, and molecular epidemiological characteristics of KP-PLA patients in Southeastern China. Read More

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http://dx.doi.org/10.1186/s13756-019-0615-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6819602PMC
October 2019

Clostridium perfringens Septicemia with Massive Intravascular Hemolysis.

Intern Med 2020 02 31;59(4):591. Epub 2019 Oct 31.

Department of Internal Medicine, Suwa Central Hospital, Japan.

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http://dx.doi.org/10.2169/internalmedicine.3793-19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7056373PMC
February 2020