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J Indian Soc Periodontol 2021 May-Jun;25(3):258-261. Epub 2021 May 3.

Department of Periodontology and Oral Implantology, Surendera Dental College and Research Institute, Sri Ganganagar, Rajasthan, India.

Inflammatory fibrous hyperplasia, pyogenic granuloma, peripheral ossifying fibroma, irritational fibroma (IF), peripheral giant cell granuloma, etc., are the different types of reactive gingival lesions that may occur in response to mild chronic irritation associated with subgingival factors, root remnant, iatrogenic factors, and trauma. Gingival IF is one of the most common reactive lesions and is usually sessile in nature, and its size is usually not more than 1. Read More

J Indian Soc Periodontol 2021 May-Jun;25(3):254-257. Epub 2021 May 3.

Department of Oral Medicine and Radiology, Nair Hospital Dental College, Dr. A. L Nair Road, Mumbai Central, Mumbai, Maharashtra, India.

Capillary hemangiomas and pyogenic granuloma (PG) are well-recognized benign entities of the oral cavity which are vascular in origin. PG is said to have a predilection for gingival area, whereas capillary hemangioma involves the lips, cheek, and tongue. They may mimic more serious conditions such as malignancies making the clinical diagnosis quite challenging. Read More

Indian J Otolaryngol Head Neck Surg 2021 Jun 15;73(2):167-173. Epub 2020 Jul 15.

Department of Oral Medicine and Radiology, Government Dental College and Hospital, Ahmedabad, Gujarat India.

Sclerotherapy is a targeted elimination of small vessels, varicose veins, and vascular anomalies by the injection of a sclerosant. Sclerotherapy aims to damage the vessel wall and transform it into fibrous tissue. The present study was conducted to evaluate the efficacy of a sclerosing agent 3% polidocanol in the treatment of vascular lesions and pyogenic granuloma. Read More

Cureus 2021 May 17;13(5):e15076. Epub 2021 May 17.

Dermatology, Mahoney Dermatology, Pinellas Park, USA.

Pyogenic granulomas represent benign vascular tumors that can present on the skin and mucous membranes. Multiple etiologic agents have been implicated in the pathogenesis including several systemic medications. Two notable oncologic therapies, epidermal growth factor receptor inhibitors and vascular endothelial growth factor receptor inhibitors, have each been associated with drug-induced pyogenic granulomas. Read More

Am J Case Rep 2021 Jun 19;22:e929690. Epub 2021 Jun 19.

Department of Clinical and Experimental Medicine, University of Foggia, Foggia, Italy.

BACKGROUND A pyogenic granuloma is an inflammatory exophytic lesion that can occur in the oral cavity. Numerous factors are involved in the etiology of the lesion and can lead to the tissue proliferation underlying the lesion's characteristic appearance. The main treatment is surgical excision with careful curettage of the surrounding tissues. Read More

Case Rep Dent 2021 21;2021:5575896. Epub 2021 May 21.

Department of Oral and Maxillofacial Surgery, Saitama Medical Center, Saitama Medical University, Saitama, Japan.

Pyogenic granuloma (PG) refers to a common, acquired, benign, and vascular tumor that arises in tissues such as the skin and mucous membranes. However, it is extremely rare for PG to arise from an empty socket after tooth extraction. Herein, we describe a rare case of PG that arose from the empty extraction socket of the second molar adjacent to a dentigerous cyst of the left mandibular wisdom tooth in a 57-year-old man. Read More

Dermatol Ther 2021 Jun 5:e15024. Epub 2021 Jun 5.

Department of Dermatology, Dr Ram Manohar Lohia Hospital and ABVIMS, New Delhi, India.

Dermatol Ther 2021 Jun 2:e15016. Epub 2021 Jun 2.

Section of Dermatology, Department of Biomedical Science and Human Oncology, University of Bari, Bari, Italy.

An increasing use of beta-blockers in dermatology has been described over the last 10 years, despite the fact that their use in diseases other than infantile hemangiomas is off-label. This review discusses the emerging role of topical beta-blockers in the treatment of infantile hemangioma, but also pyogenic granuloma, Kaposi sarcoma, wounds and nail paronychia. Data in literature demonstrate that topical beta-blockers are a safe and valid therapeutic option in numerous cutaneous diseases. Read More

Trop Doct 2021 May 27:494755211017422. Epub 2021 May 27.

Department of Cardiology, 29354SCTIMST, India.

Cardiac involvement in tuberculosis mainly affects the pericardium, with the myocardium being rarely involved. Coronary stent infection in patients with tuberculosis is rarely described. Myocardial involvement in tuberculosis can lead to complications such as ventricular granuloma, or dysrhythmias. Read More

Dermatol Ther 2021 May 24:e14998. Epub 2021 May 24.

Section of Dermatology, Department of Clinical Medicine and Surgery, University of Naples Federico II, Naples, Italy.

BMC Oral Health 2021 05 17;21(1):265. Epub 2021 May 17.

Department of Oral Pathology, National Clinical Research Center for Oral Diseases, Peking University School and Hospital of Stomatology, Beijing, China.

Background: While inflammatory diseases such as gingivitis and periodontitis induced by dental plaque biofilms constitute the majority of gingival lesions, gingiva can also be affected by a variety of diseases with aetiologies different from bacterial biofilms. The aim of this study was to retrospectively analyze the frequency and distribution of non-dental plaque-induced gingival diseases (NDPIGDs) in the Chinese population in a single institute.

Methods: A total of 6859 samples of biopsied gingival diseases during the period 2000-2019 were obtained from the Department of Pathology, Peking University Hospital of Stomatology. Read More

Endoscopy 2021 May 12. Epub 2021 May 12.

Center for Gastrointestinal Endoscopy, Surgery and Anatomy Department, Faculty of Medicine of Ribeirão Preto, Ribeirão Preto, Brazil.

J Clin Ultrasound 2021 May 12. Epub 2021 May 12.

Department of Ultrasound Medicine, West China Hospital, Sichuan University, Chengdu, China.

Intravascular lobular capillary hemangioma (ILCH) is a rare variant of pyogenic granuloma, which develops within the lumen of a blood vessel. Here, we report the case of a 38-year-old male presenting with a mobile, incompressible, nonpulsatile nodule in the superficial fascia of the forearm. A first ultrasonographic examination diagnosed the mass as intravascular thrombosis with partial recanalization. Read More

Orbit 2020 Dec 1:1-6. Epub 2020 Dec 1.

Department of Ophthalmology and Visual Sciences, Illinois Eye and Ear Infirmary, University of Illinois at Chicago, Chicago, Illinois, USA.

: Lid-sharing approaches are often advocated for repair of large full thickness lower eyelid defects, however result in temporary visual obstruction and the need for a second-stage procedure. The authors describe and report outcomes using a one-stage technique utilizing a free tarsoconjunctival graft (TCG) and musculocutaneous transposition flap (MCT) to repair defects up to 90% of the lower eyelid.: A retrospective chart review on patients that had undergone full thickness lower eyelid reconstruction using a TCG and MCT between the dates of 1/1/2015 to 3/1/2020 was performed. Read More

Nihon Shokakibyo Gakkai Zasshi 2021 ;118(5):462-472

Department of Internal Medicine II, Shimane University.

A 57-year-old female with a history of Cowden's disease was referred to our hospital because of black stool, loss of consciousness, and severe anemia. Upper and lower gastrointestinal endoscopy findings could not confirm the source of hemorrhage. Capsule endoscopy (CE) of the small intestine showed an active exudative hemorrhagic site near the ileum, although a definitive diagnosis was difficult. Read More

EJVES Vasc Forum 2021 24;50:32-36. Epub 2020 Dec 24.

Department of Vascular Surgery and Kidney Transplantation, University of Strasbourg, France.

Introduction: Intravascular lobular capillary haemangioma is a rare benign intravascular tumour, especially in large vessels. This is the report of a case and associated literature review.

Report And Literature Review: This is the report of the first case of an intravenous lobular capillary haemangioma (ILCH) of the superior vena cava (SVC). Read More

Indian J Ophthalmol 2021 05;69(5):1155-1160

Department of Orbit and Oculoplasty, Sadguru Netra Chikitsalya and Postgraduate Institute of Ophthalmology, Jankikund, Chitrakoot, Madhya Pradesh, India.

Purpose: To study topical timolol (0.5%) as a first-line treatment in ophthalmic pyogenic granuloma (PG) in terms of safety and efficacy.

Methods: This was a prospective, interventional, single-arm study conducted at a tertiary eye care hospital in central India. Read More

Pan Afr Med J 2021 9;38:145. Epub 2021 Feb 9.

Private Dental Practice, Cagliari, Italy.

BMC Oral Health 2021 04 23;21(1):204. Epub 2021 Apr 23.

Department of Odontoestomatology, Faculty of Medicine and Health Sciences (Dentistry), Bellvitge Campus, University of Barcelona, Barcelona, Spain.

Background: The aim of the present investigation was to evaluate the literature recurrence of peripheral giant cell granuloma and pyogenic granuloma associated with dental implants. It's important to know the characteristics present in these lesions and possible effects on the prognosis of dental implants.

Methods: An electronic search without time restrictions was done in the databases: PubMed/Medline. Read More

J Indian Soc Periodontol 2021 Mar-Apr;25(2):162-165. Epub 2021 Mar 1.

Department of Oral Medicine and Radiology, Modern Dental College and Research Center, Indore, Madhya Pradesh, India.

Pyogenic granuloma is a commonly occurring inflammatory hyperplasia involving the oral cavity. Surgical resection of the lesion is the mainstay treatment of pyogenic granuloma. However, intraoperative bleeding, postoperative infection, and recurrence chances are more with the surgical technique. Read More

Acta Dermatovenerol Croat 2020 Dec;28(7):233-235

Martyna Sławińska MD, PhD, Department of Dermatology, Venereology and Allergology Medical University of Gdańsk, Smoluchowskiego 17 Street, 80-214 Gdańsk;

Giant molluscum contagiosum (MC) is a peculiar variant of the disease with the presence of multiple or single lesions larger than 5 mm. In contrast to typical molluscum contagiosum, dermoscopic features of giant lesions have been poorly described, and none of the reports included multiple giant lesions in an immunocompromised patient. We present a patient with acquired immunodeficiency syndrome diagnosed with multiple giant molluscum contagiosum along with the dermoscopic features of this entity. Read More

Surg Case Rep 2021 Apr 7;7(1):85. Epub 2021 Apr 7.

Department of Gastroenterological Surgery, Toranomon Hospital, #311, 6-5-38 Akasaka, Minato-ku, Tokyo, 107-0052, Japan.

Background: Pyogenic granuloma is a benign vascular tumor, usually occurring on the skin or in the oral cavity. Small intestinal pyogenic granuloma is extremely rare, but intestinal intussusception due to the tumor is even rarer. Only 3 cases have been reported in the English literature at this writing. Read More

Ocul Immunol Inflamm 2021 Apr 7:1-3. Epub 2021 Apr 7.

Department of Ophthalmology, Faculty of Medicine, Agri Ibrahim Cecen University Rectorate, Agri, Turkey.

: This study intended to illustrate a rare case of pyogenic granuloma (PG) in retinal vein occlusion (RVO) patient after dexamethasone (DEX) implant therapy.: A 58-year-old female who underwent DEX implant therapy a month ago due to RVO presented with a mass in her right eye. Anterior segment analysis revealed a slowly enlarging, round, fleshy vascular mass indicating PG located at the injection site. Read More

Scars Burn Heal 2021 Jan-Dec;7:2059513120986687. Epub 2021 Jan 22.

Autonomus Service Institute of Biomedicine, Caracas, Venezuela.

Introduction: Pyogenic granuloma (PG) is a reactive inflammatory vascular lesion of the skin and mucous membranes, characterised by the presence of enlarged venules and seamed and seamless capillaries with plump endothelial cells (EC), and numerous macrophages. EC activation upregulates the synthesis of galectins and induces their translocation to the EC surface promoting angiogenesis and lymphangiogenesis, particularly galectin-1 (Gal-1), Gal-3 and Gal-8. However, the presence and distribution of Gal-1, -3 and -8, as well as their implications in the pathogenesis of PG, has not been considered. Read More

Indian Dermatol Online J 2021 Jan-Feb;12(1):142-146. Epub 2021 Jan 16.

Department of Pathology, Government Medical College, Nagpur, Maharashtra, India.

Pyogenic granuloma (PG), also called a lobular capillary hemangioma, is a benign vascular proliferation of skin or mucous membrane. It classically presents as a solitary friable nodule over the face or distal extremities. Multiple disseminated PG is a rare form generally reported after trauma such as burn injury. Read More

Clin Exp Dermatol 2021 Mar 25. Epub 2021 Mar 25.

Department of Dermatology, Lokmanya Tilak Municipal Medical College and General Hospital, Mumbai, India.

Background: Recurrent bleeding episodes are often a cause of significant anxiety in patients with pyogenic granuloma (PG). The idea of using common salt for the treatment of PG arose from the need for a relatively safe and effective treatment because of the recurrent nature of the lesion.

Methods: A prospective open-label uncontrolled study of 50 patients was conducted. Read More

Dermatol Clin 2021 Apr;39(2):281-292

Dermatology OHSU, Oregon Dermatology and Research Center, 2565 Northwest Lovejoy Street, Portland, OR, USA. Electronic address:

This article describes nail tumors and their clinical features, biologic behavior, and treatment. Tumors included are onychopapilloma, onychomatricoma, periungual fibromas/fibrokeratomas, glomus tumors, subungual exostosis, myxoid cysts, and squamous cell carcinoma. Read More

J Paediatr Child Health 2021 03;57(3):459-460

Department of Dermatology, Coimbra Hospital and University Centre, Coimbra, Portugal.

Front Pediatr 2021 24;9:649610. Epub 2021 Feb 24.

Department of Dermatology and Dermatologic Surgery, Medical University of South Carolina, Charleston, SC, United States.

[This corrects the article DOI: 10.3389/fped.2020. Read More

J Cutan Pathol 2021 Jul 25;48(7):954-957. Epub 2021 Mar 25.

Department of Pathology, Robert J. Tomsich Pathology and Laboratory Medicine, Cleveland Clinic, Ohio, USA.

Pyogenic granuloma (PG) represents a polypoid and lobular, capillary lesion, resembling granulation tissue, usually occurring on skin or mucosal surfaces. The occurrence of metaplastic ossification is extremely rare in PG. We present three cases of PG with metaplastic ossification. Read More