3,174 results match your criteria Pyoderma Gangrenosum


Extraintestinal manifestations in inflammatory bowel disease - epidemiology, genetics, and pathogenesis.

Expert Rev Gastroenterol Hepatol 2019 Feb 4:1-11. Epub 2019 Feb 4.

a Department of Gastroenterology and Hepatology , University Hospital Zurich , Zurich , Switzerland.

Introduction: Inflammatory bowel disease (IBD) is a chronic inflammatory disorder, primarily of, but not restricted to the gut. Extraintestinal manifestations (EIMs) are frequently observed and involve the joints, eyes, hepatobiliary tract, and skin. Areas covered: In this review, we discuss classical EIM focusing on epidemiology, genetics, and pathogenesis, highlighting recent advances in the understanding of EIM. Read More

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http://dx.doi.org/10.1080/17474124.2019.1574569DOI Listing
February 2019

Dermatologic Urgencies and Emergencies: What Every Pathologist Should Know.

Arch Pathol Lab Med 2019 Feb 20. Epub 2019 Feb 20.

From the Department of Dermatology, Saint Louis University, St Louis, Missouri (Dr Abate);the Departments of Dermatology (Dr Battle),and Pathology (Drs Gardner and Shalin),University of Arkansas for Medical Sciences, Little Rock; and the Department of Dermatology, University of Mississippi Medical Center, Jackson (Dr Emerson).

Context.—: Fatal dermatologic diseases and ones with high morbidity can occur in the inpatient setting. In such cases, prompt and accurate assessment of a bedside skin biopsy is required. Read More

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http://dx.doi.org/10.5858/arpa.2018-0239-RADOI Listing
February 2019

Peristomal pyoderma gangrenosum: an exceedingly rare and overdiagnosed entity?

J Am Acad Dermatol 2019 Feb 14. Epub 2019 Feb 14.

Department of Dermatology, University of California, Davis Medical Center, Sacramento, CA, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01909622193028
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http://dx.doi.org/10.1016/j.jaad.2019.02.026DOI Listing
February 2019
2 Reads

Colocutaneous fistula through ulcerative colitis and cancer to the pyoderma gangrenosum: a never-ending story for a single patient. Case report.

G Chir 2019 Jan-Feb;40(1):39-43

Background: Inflammatory bowel diseases may be associated with many extraintestinal complications, that in some cases can represent the first onset of these disorders. In particular during the course of the disease, Ulcerative Colitis develops extraintestinal manifestations very frequently. One of the rarest is pyoderma gangrenosum, a noninfectious neuthrophilic dermatosis, that can involve most commonly legs but also other parts of the skin or mucosas. Read More

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February 2019
1 Read

Intravenous immunoglobulin treatment: Where do dermatologists stand?

Authors:
Selma Emre

Dermatol Ther 2019 Feb 13:e12854. Epub 2019 Feb 13.

Department of Dermatology, Yildirim Beyazit University, Medical School, Ankara, Turkey.

Intravenous immunoglobulins are therapeutic products, comprising polyclonal IgGs, which are obtained from human plasma pool of healthy blood donors. Despite the lack of FDA approval, the experience of using IVIG in various dermatological diseases increases day by day and exciting results are reported. However, experience with the use of IVIG in dermatological indications are mostly case reports whereas randomized, controlled, double-blind, multicentric studies have not been performed. Read More

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http://dx.doi.org/10.1111/dth.12854DOI Listing
February 2019
3 Reads

A case of persistent fever, cutaneous manifestations and pulmonary and splenic nodules: clinical experience and a literature review.

Intern Med J 2019 Feb;49(2):247-251

Department of Respiratory, Peking University Shenzhen Hospital, Shenzhen, Gangdong, China.

Pyoderma gangrenosum (PG) is a rare and recurrent ulcerating, non-infectious, inflammatory dermatosis, with occasional concomitant extracutaneous manifestations. The pathogenesis and aetiology of PG are unknown. Moreover, early diagnosis is challenging because there are several visceral manifestations that may occur prior to the skin findings, such that misdiagnosis of PG as an infection is common. Read More

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http://dx.doi.org/10.1111/imj.14201DOI Listing
February 2019
1 Read

Successful Treatment of Pyoderma Gangrenosum with Concomitant Tofacitinib and Infliximab.

Inflamm Bowel Dis 2019 Feb 8. Epub 2019 Feb 8.

Division of Gastroenterology and Hepatology, Washington University School of Medicine, St. Louis, Missouri.

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http://dx.doi.org/10.1093/ibd/izz015DOI Listing
February 2019

Overall and Subgroup Prevalence of Pyoderma Gangrenosum Among Patients with Hidradenitis Suppurativa: a population based analysis in the United States.

J Am Acad Dermatol 2019 Feb 6. Epub 2019 Feb 6.

Department of Dermatology, Donald and Barbara Zucker School of Medicine at Hofstra Northwell. New Hyde Park, NY, USA. Electronic address:

Background: Hidradenitis suppurativa (HS) and pyoderma gangrenosum (PG) are reported to coexist, although prevalence of PG among HS patients has not been systematically evaluated.

Objective: To evaluate PG prevalence among HS patients.

Methods: Cross-sectional analysis of adults with PG among HS and non-HS patients using electronic health records data from a population-based sample of 55 million patients. Read More

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http://dx.doi.org/10.1016/j.jaad.2019.02.004DOI Listing
February 2019
1 Read

IL-17E (IL-25) enhances innate immune responses during skin inflammation.

J Invest Dermatol 2019 Feb 6. Epub 2019 Feb 6.

Department of Pathology and Immunology, Faculty of Medicine, University of Geneva, Geneva, Switzerland. Electronic address:

IL-17E (IL-25) is a member of the IL-17 cytokine family involved in the promotion of type 2 immune responses. Recently, IL-17E has been reported to be upregulated in distinct skin inflammatory diseases such as psoriasis, atopic and contact dermatitis. We assessed the role played by IL-17E in skin inflammation. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S0022202X193010
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http://dx.doi.org/10.1016/j.jid.2019.01.021DOI Listing
February 2019
4 Reads

Cutaneous paraneoplastic syndromes.

Semin Diagn Pathol 2019 Jan 31. Epub 2019 Jan 31.

PRW Laboratories, Charlottesville, VA, United State.

A variety of cutaneous abnormalities can be seen in patients with malignant diseases, some of which are infectious, with others representing direct involvement of the skin by the underlying disorder. Yet another group of lesions can be regarded as associated markers of the malignant process, and, as such, are termed "paraneoplastic." This review considers the latter collection of conditions, grouping them by the generic type of malignancy that is usually linked to the paraneoplasia. Read More

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http://dx.doi.org/10.1053/j.semdp.2019.01.001DOI Listing
January 2019
1 Read

Sweet syndrome with pseudocarcinomatous hyperplasia: A case report and review of the literature.

J Cutan Pathol 2019 Feb 7. Epub 2019 Feb 7.

University of Minnesota, Department of Dermatology, 516 Delaware Street S.E., Mail Code 98, Phillips-Wangensteen Bldg., Suite 4-240, Minneapolis, Minnesota 55455.

Pseudocarcinomatous (pseudoepitheliomatous) hyperplasia represents reactive epidermal change mimicking squamous cell carcinoma (SCC), owing to a variety of inflammatory and neoplastic phenomena, including deep fungal infections, CD30-positive lymphomas, and others. We report a case of Sweet syndrome (SS) arising in a patient with acute myelogenous leukemia, with persistent orolabial involvement which mimicked SCC both clinically and microscopically, but resolved entirely with adequate corticosteroid treatment. Clinicians should be aware that neutrophilic dermatoses such as SS and pyoderma gangrenosum may rarely exhibit pseudocarcinomatous epidermal changes similar to those seen in soft tissue infections and other inflammatory dermatoses. Read More

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http://dx.doi.org/10.1111/cup.13436DOI Listing
February 2019
1 Read

Arterial hand ulcer: A common disease in an uncommon location.

JAAD Case Rep 2019 Feb 25;5(2):147-149. Epub 2019 Jan 25.

Oregon Health and Science University, School of Medicine, Portland, Oregon.

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http://dx.doi.org/10.1016/j.jdcr.2018.12.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355430PMC
February 2019

Pyoderma gangrenosum: a presenting sign of myelodysplastic syndrome in undiagnosed Fanconi anemia.

Dermatol Online J 2019 Jan 15;25(1). Epub 2019 Jan 15.

Department of Dermatology, Indiana University School of Medicine, Indianapolis, Indiana.

A 26-year-old man with a history of congenital bilateral microtia, unilateral renal agenesis, left aural atresia, and right external auditory canal occlusion admitted for right rib cartilage graft harvest and left ear re-construction. Following surgery, an ulceration with violaceous borders and a yellow fibrinous base unresponsive to broad-spectrum antibiotics developed at the harvest site. The wound was expanding and not responsive to systemic broad-spectrum antibiotics. Read More

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January 2019
2 Reads

Occurrence of skin manifestations in patients of the Swiss Inflammatory Bowel Disease Cohort Study.

PLoS One 2019 25;14(1):e0210436. Epub 2019 Jan 25.

Department of Gastroenterology and Hepatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.

Background/aims: Extraintestinal cutaneous manifestations of IBD represent a severe disease complication and an early and accurate treatment might positively influence the disease course. Using the patient collective of the Swiss IBD Cohort Study (SIBDCS), we analysed epidemiological as well as clinical factors being associated with the onset of pyoderma gangrenosum, erythema nodosum and aphthous ulcers in IBD patients.

Methods: We included 3266 SIBDCs patients, 1840 with Crohn's disease (CD) and 1426 with ulcerative colitis (UC) or IBD unclassified (IBDU) and analysed the association of cutaneous manifestations with age, age at diagnosis time, type of disease, gender, family history, HLA-allotype, smoking, intestinal disease activity, therapy and other extraintestinal manifestations (EIM). Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0210436PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347222PMC
January 2019

[One case of pyoderma gangrenosum in the lower limbs in Tibetan Plateau treated with vacuum sealing drainage combined with irrigation of oxygen loaded fluid].

Zhonghua Shao Shang Za Zhi 2019 Jan;35(1):69-71

Department of Burns and Plastic Surgery, the General Hospital of PLA Tibet Military Area Command, Lhasa 850000, China.

A 54 years old male patient with chronic leg ulcers was admitted in our hospital in November 2017. He was diagnosed as pyoderma gangrenosum by the pathological examination. Then the wound was treated with simple vacuum sealing drainage combined with irrigation of oxygen loaded fluid. Read More

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http://dx.doi.org/10.3760/cma.j.issn.1009-2587.2019.01.013DOI Listing
January 2019

A case of erosive pustular dermatosis of the scalp in a pediatric patient.

JAAD Case Rep 2019 Feb 11;5(2):118-120. Epub 2019 Jan 11.

Department of Dermatology, University of Texas Medical Branch, Galveston, Texas.

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http://dx.doi.org/10.1016/j.jdcr.2018.11.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330372PMC
February 2019

Pyoderma gangrenosum as first manifestation of Crohn's disease.

Tech Coloproctol 2019 Jan 17;23(1):79-80. Epub 2019 Jan 17.

Department of Medical and Surgical Sciences, University of Catanzaro, Catanzaro, Italy.

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http://dx.doi.org/10.1007/s10151-018-1916-9DOI Listing
January 2019

Managing Ulcers Associated with Pyoderma Gangrenosum with a Urinary Bladder Matrix and Negative-Pressure Wound Therapy.

Adv Skin Wound Care 2019 Feb;32(2):70-76

At the Wake Forest Baptist Medical University in Winston-Salem, North Carolina, Claire Sanger Dillingham, DO, is Associate Professor, Plastic and Reconstructive Surgery Department; and Joseph Jorizzo, MD, is Professor, Dermatology Department. The authors have disclosed no financial relationships related to this article. Submitted March 21, 2018; accepted in revised form June 12, 2018.

Pyoderma gangrenosum (PG) is a rare disease that presents as painful ulcerations with inflammation and undermining at the borders. The ulcers can occur anywhere on the body but are most commonly seen on the lower extremities. The etiology of PG is unknown, and there are no definitive diagnostic criteria; PG is a diagnosis of exclusion, which can present serious delays in treatment. Read More

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http://dx.doi.org/10.1097/01.ASW.0000546120.32681.bcDOI Listing
February 2019
9 Reads

Hidradenitis Suppurativa: A Systematic Review Integrating Inflammatory Pathways Into a Cohesive Pathogenic Model.

Front Immunol 2018 14;9:2965. Epub 2018 Dec 14.

Department of Dermatology, Erasmus University Medical Center, Rotterdam, Netherlands.

The pathogenesis of hidradenitis suppurativa (HS) is not fully understood. This systematic review examined the latest evidence for molecular inflammatory pathways involved in HS as a chronic inflammatory skin disease. A systematic literature search was performed in PubMed/Medline and EMBASE from January 2013 through September 2017, according to the preferred reporting items for systematic reviews and meta-analyses (PRISMA). Read More

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https://www.frontiersin.org/article/10.3389/fimmu.2018.02965
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http://dx.doi.org/10.3389/fimmu.2018.02965DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302105PMC
December 2018
12 Reads

Successful treatment with tacrolimus of refractory pyoderma gangrenosum with pouchitis after restorative proctocolectomy for ulcerative colitis.

Immunol Med 2018 Sep 3;41(3):142-146. Epub 2018 Dec 3.

a Department of Gastroenterology and Hematology , Hirosaki University Graduate school of medicine , Hirosaki , Japan.

We describe herein a case of severe relapsed pyoderma gangrenosum (PG) concomitantly with severe pouchitis treated by tacrolimus. A 25-year-old woman had undergone proctocolectomy with construction of ileo-anal pouch surgery for refractory ulcerative colitis (UC). She first developed PG with refractory pouchitis, and infliximab (IFX) was administered to induce remission due to resistance to glucocorticoid therapy. Read More

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https://www.tandfonline.com/doi/full/10.1080/25785826.2018.1
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http://dx.doi.org/10.1080/25785826.2018.1531194DOI Listing
September 2018
12 Reads

Erosive pustular dermatosis of the scalp: A neutrophilic folliculitis within the spectrum of neutrophilic dermatoses: A clinicopathologic study of 30 cases.

J Am Acad Dermatol 2018 Oct 25. Epub 2018 Oct 25.

Department of Clinical-Surgical, Diagnostic, and Pediatric Science, Institute of Dermatology, Fondazione IRCCS Policlinico San Matteo, University of Pavia, Pavia, Italy.

Background: It is general opinion that histopathology is nonspecific and of little value in diagnosing erosive pustular dermatosis of the scalp (EPDS).

Objectives: Clinicopathologic correlation of erosive pustular dermatosis of the scalp.

Methods: We reviewed the clinical and pathologic records of patients with a clinicopathologic diagnosis of EPDS between 2011 and 2016 at the Dermatopathology Unit of Turin University. Read More

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http://dx.doi.org/10.1016/j.jaad.2018.10.029DOI Listing
October 2018
1 Read

Pyoderma Gangrenosum of the Finger associated with Pediatric Ulcerative Colitis.

J Pediatr Gastroenterol Nutr 2018 Dec 29. Epub 2018 Dec 29.

Department of Pediatrics, Gunma University Graduate School of Medicine, Maebashi, Gunma, Japan.

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http://Insights.ovid.com/crossref?an=00005176-900000000-9659
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http://dx.doi.org/10.1097/MPG.0000000000002255DOI Listing
December 2018
1 Read

Neutrophilic Dermatosis in Pregnancy: An Uncommon Course.

Open Access Maced J Med Sci 2018 Dec 18;6(12):2393-2394. Epub 2018 Dec 18.

Section of Dermatology, Department of Clinical Medicine and Surgery, University of Naples Federico II, Naples, Italy.

Pyoderma gangrenosum (PG) is a neutrophilic-mediated inflammatory skin disease characterised by the rapid onset of painful, hemorrhagic pustules developing into necrotic ulcers occurring predominantly in women aged 20-50 years. According to the literature, all patients reported no change or worsening of the disease during pregnancy. We herein present the case of a 34-year-old woman that developed a neutrophilic dermatosis of the hand reporting complete resolution of the skin disease during pregnancy. Read More

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http://dx.doi.org/10.3889/oamjms.2018.453DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311494PMC
December 2018

Pyoderma gangrenosum and tumour necrosis factor alpha inhibitors: A semi-systematic review.

Int Wound J 2019 Jan 3. Epub 2019 Jan 3.

Department of Dermatology, Aarhus University Hospital, Aarhus, Denmark.

Pyoderma gangrenosum (PG) is a rare ulcerative skin disease that presents a therapeutic challenge. Tumour necrosis factor alpha (TNFα) inhibitors have been reported to successfully control PG. Our aim was to systematically evaluate and compare the clinical effectiveness of TNFα inhibitors in adults with PG. Read More

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http://dx.doi.org/10.1111/iwj.13067DOI Listing
January 2019

Biologics and immunoglobulins in the treatment of pyoderma gangrenosum - analysis of 52 patients.

J Dtsch Dermatol Ges 2019 Jan 28;17(1):32-41. Epub 2018 Dec 28.

Center of Competence for Health Care Research in Dermatology (CVderm), Institute for Health Care Research in Dermatology and Nursing (IVDP), Hamburg-Eppendorf University Medical Center, Hamburg, Germany.

Background And Objectives: Corticosteroids and cyclosporine A are frequently ineffective as first-line therapies in the treatment of pyoderma gangrenosum (PG) and associated with a number of adverse effects. The objective of the present study was to analyze the effectiveness and safety of biologics and intravenous immunoglobulins (IVIGs).

Patients And Methods: Retrospective, dual-center cohort study analyzing the treatment outcome in patients with PG who received biologics and IVIGs. Read More

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http://doi.wiley.com/10.1111/ddg.13741
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http://dx.doi.org/10.1111/ddg.13741DOI Listing
January 2019
13 Reads

Pyoderma gangrenosum of the breast.

BMJ Case Rep 2018 Dec 22;11(1). Epub 2018 Dec 22.

Department of General Medicine, Saiseikai Fukuoka General Hospital, Fukuoka, Japan.

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http://dx.doi.org/10.1136/bcr-2018-228243DOI Listing
December 2018

Peritoneal Dialysis Exit Site Pyoderma Gangrenosum: A Case Report.

Case Rep Nephrol Dial 2018 Sep-Dec;8(3):239-245. Epub 2018 Nov 14.

Section of Nephrology, Department of Medicine, Regina, Saskatchewan, Canada.

Background: Pyoderma gangrenosum (PG) is a rare, chronic inflammatory condition exhibiting mucopurulent or hemorrhagic exudates. The majority of cases are associated with inflammatory bowel disease, rheumatological diseases, and hematological malignancies. In the absence of typical serological markers and specific histopathological changes, the diagnosis is often clinical. Read More

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http://dx.doi.org/10.1159/000493188DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276769PMC
November 2018
1 Read

Post-surgical pyoderma gangrenosum of the breast: needs for early diagnosis and right therapy.

Breast Cancer 2018 Dec 18. Epub 2018 Dec 18.

Oncologic Breast Surgery Unit, Department of Medical and Surgical Sciences for Children and Adults, University Hospital of Modena, Modena, Italy.

Post-surgical pyoderma gangrenosum (PSPG) of the breast is a rare dermatosis that worsens surgical manipulation, with a chronical relapsing course. Diagnosis is mostly clinical and made by exclusion after the failure of antibiotic therapies and surgical debridement, while the mainstay of therapy is corticosteroid-based. Here we report a case of PSPG of the breast in a young woman with breast cancer, to emphasize the needs of an early and accurate diagnosis, to guarantee the most efficacious treatment and to avoid life-threatening complications. Read More

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http://link.springer.com/10.1007/s12282-018-00940-5
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http://dx.doi.org/10.1007/s12282-018-00940-5DOI Listing
December 2018
6 Reads

Vasculitis in Systemic Autoinflammatory Diseases.

Front Pediatr 2018 3;6:377. Epub 2018 Dec 3.

Division of Pediatric Rheumatology, Department of Pediatrics, Hacettepe University Faculty of Medicine, Ankara, Turkey.

Autoinflammatory diseases (AID) are diseases of the innate immune system, characterized by recurrent episodes of localized or systemic inflammation. Vasculitis may accompany AID. The causes of the association of vasculitis with monogenic AID are still debated. Read More

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http://dx.doi.org/10.3389/fped.2018.00377DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287042PMC
December 2018
15 Reads

In response to: "New validated diagnostic criteria for pyoderma gangrenosum".

J Am Acad Dermatol 2018 Dec 14. Epub 2018 Dec 14.

Department of Dermatology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01909622183308
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http://dx.doi.org/10.1016/j.jaad.2018.12.013DOI Listing
December 2018
19 Reads

New validated diagnostic criteria for pyoderma gangrenosum.

J Am Acad Dermatol 2018 Dec 14. Epub 2018 Dec 14.

Division of Immunology and Rheumatology, Department of Dermatology, Stanford University, Stanford, California; Division of Immunology and Rheumatology, Department of Internal Medicine, Stanford University, Stanford, California.

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http://dx.doi.org/10.1016/j.jaad.2018.08.068DOI Listing
December 2018
1 Read

Safety and Efficacy of Rituximab in Multiple Sclerosis: A Retrospective Observational Study.

J Immunol Res 2018 12;2018:9084759. Epub 2018 Nov 12.

Nehme and Therese Tohme Multiple Sclerosis Center, American University of Beirut Medical Center, Beirut, Lebanon.

Objective: To evaluate the efficacy and safety of rituximab in multiple sclerosis in a clinical practice setting.

Methods: Clinical data for all adult patients with multiple sclerosis (MS) treated with off-label rituximab at a single MS center in Lebanon between March 2008 and April 2017 were retrospectively collected from medical charts. The main efficacy outcomes assessed were annualized relapse rate (ARR) and proportion of patients free from relapses, disability progression, or magnetic resonance imaging (MRI) activity. Read More

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https://www.hindawi.com/journals/jir/2018/9084759/
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http://dx.doi.org/10.1155/2018/9084759DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260423PMC
January 2019
5 Reads

Refractory pyoderma gangrenosum in a patient with Crohn´s Disease: complete response to Ustekinumab.

J Crohns Colitis 2018 Dec 7. Epub 2018 Dec 7.

Gastroenterology department, Hospital Garcia de Orta, Almada, Portugal.

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http://dx.doi.org/10.1093/ecco-jcc/jjy200DOI Listing
December 2018
2 Reads

Abdominal ultrasound in paraneoplastic Pyoderma gangrenosum caused by renal carcinoma.

Med Ultrason 2018 Dec;20(4):541-542

2nd Medical Clinic, UMF Iuliu Hatieganu University, Cluj-Napoca, Romania.

We present the case of a 60-year-old male patient, with refractory ulcers in the groin. Ultrasoundand CT showed a large vascularized tumor of the kidney with cystic parts and inhomogeneous dynamic behaviour. Histology demonstrated Pyoderma gangrenosum (ulcer) and well differentiated adenocarcinoma (kidney). Read More

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http://dx.doi.org/10.11152/mu-1751DOI Listing
December 2018
8 Reads

Pyoderma gangrenosum around an ileostoma: A case report.

Medicine (Baltimore) 2018 Nov;97(48):e13415

Department of Colorectal Surgery, Ningbo No.2 Hospital, No.41 Northwest Street, Ningbo, Zhejiang Province, China.

Rationale: Pyoderma gangrenosum (PG) is a rare postoperative complication of enterostomy, mostly developing from dermatitis, which may have serious consequence.

Patient Concerns: A patient with lower rectal cancer receiving low anterior resection (LAR) and protective ileostomy was initially diagnosed with dermatitis, which very quickly developed to PG, though no medical or familial history was found.

Diagnosis: We diagnosed the patient with peristoaml dermatitis starting from a tiny skin ulceration, but corrected the diagnosis to PG because of the rapid development and severe consequences. Read More

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http://dx.doi.org/10.1097/MD.0000000000013415DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283191PMC
November 2018
3 Reads

Bilateral pyoderma gangrenosum associated with ulcerative colitis and restorative proctocolectomy.

Gastroenterol Hepatol 2018 Nov 20. Epub 2018 Nov 20.

Servicio de Aparato Digestivo, Hospital Universitario Miguel Servet, Zaragoza, España.

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http://dx.doi.org/10.1016/j.gastrohep.2018.10.006DOI Listing
November 2018
1 Read

Hepatobiliary and Pancreatic: Pyoderma gangrenosum of the pancreas successfully treated with infliximab.

J Gastroenterol Hepatol 2018 Nov 22. Epub 2018 Nov 22.

Department of Gastroenterology, Academic Hospital Roeselare, Roeselare, Belgium.

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http://dx.doi.org/10.1111/jgh.14504DOI Listing
November 2018
1 Read

Utility of Skin Biopsy and Culture in the Diagnosis and Classification of Chronic Ulcers: A Single-Institution, Retrospective Study.

Am J Dermatopathol 2018 Nov 15. Epub 2018 Nov 15.

Department of Pathology, University of Washington, Seattle, WA.

In the United States, chronic ulcers affect 6.5 million people, with a cost of ≈$20 million annually. The most common etiology of chronic ulcers in the United States is venous stasis, followed by arterial insufficiency and neuropathic ulcers. Read More

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http://dx.doi.org/10.1097/DAD.0000000000001299DOI Listing
November 2018
8 Reads

Association of pyoderma gangrenosum, erythema nodosum and aseptic liver abscess without significant underlying disease.

Clin Exp Dermatol 2019 Mar 20;44(2):e16-e17. Epub 2018 Nov 20.

Department of Dermatology, Fukushima Medical University, Hikarigaoka 1, Fukushima, 960 1295, Japan.

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http://dx.doi.org/10.1111/ced.13838DOI Listing
March 2019
1 Read

Diagnostic pitfalls in the differentiation between pyoderma gangrenosum and necrotizing fasciitis.

Acta Orthop Belg 2018 Mar;84(1):17-24

Pyoderma gangrenosum and necrotizing fasciitis are two rare pathologic entities with a similar clinical image, but a who require a very different management. In general physicians, orthopedics, dermatologists, plastic surgeons will hardly ever see it, but when they do it is very important to distinguish between both. In this paper with the focus on the practical approach ,we expose the diagnostic pitfalls in the differential diagnosis, explain how to prevent them and summarize the evidence on therapeutic management. Read More

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March 2018
1 Read

Two cases of maggot debridement therapy in pyoderma gangrenosum.

JAAD Case Rep 2018 Nov 10;4(10):1027-1029. Epub 2018 Nov 10.

Department of Dermatology, Brigham and Women's Hospital, Boston, Massachusetts.

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http://dx.doi.org/10.1016/j.jdcr.2018.07.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232634PMC
November 2018
2 Reads

Wound Healing Disorder Caused by Pyoderma Gangrenosum.

Am Surg 2018 Mar;84(3):e112-e113

Department of Dermatology, Universitaetsklinikum Muenster, Muenster, Germany.

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March 2018
1 Read

Pyoderma Gangrenosum After Facelift and Otoplasty Surgery: Case Presentations and Literature Review.

Authors:
Joe Niamtu

J Oral Maxillofac Surg 2018 Oct 24. Epub 2018 Oct 24.

Private Practice, Cosmetic Facial Surgery, Midlothian, VA. Electronic address:

Purpose: Pyoderma gangrenosum (PG) is an uncommon autoimmune, neutrophilic, ulcerative skin condition of uncertain etiology believed to result from dysregulation of the immune system. Although this entity is well recognized by dermatologists, other specialists are less familiar with diagnosis and treatment. This report describes a severe PG reaction to an elective cosmetic facelift, which is believed to be the second reported case of PG after facelift surgery. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S02782391183119
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http://dx.doi.org/10.1016/j.joms.2018.10.011DOI Listing
October 2018
8 Reads

Clinical outcomes and response of patients applying topical therapy for pyoderma gangrenosum: A prospective cohort study.

Authors:
Eden Lake

J Am Acad Dermatol 2018 Nov 14. Epub 2018 Nov 14.

Loyola Univ Medical Center Dermatology, 321 N La Grange Rd, La Grange Park, IL. Electronic address:

Pyoderma gangrenosum is a painful ulcerating disease. The current evidence base for treatment is limited. In a large prospective study of topical treatments, 44% of patients were healed by 6 months. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01909622183288
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http://dx.doi.org/10.1016/j.jaad.2018.11.003DOI Listing
November 2018
10 Reads

[Pitfalls of Differential Diagnosis in Dermatologic Surgery].

Dtsch Med Wochenschr 2018 Nov 15;143(23):1682-1689. Epub 2018 Nov 15.

Evaluation of skin diseases can be challenging for non-dermatologists. Even obvious well-characterized skin pathologies might be misleading and thus treatment can fail. Particularly the differentiation of surgical treated entities is important, for example the management of a wound healing disturbance profoundly differs from that of a pyoderma gangrenosum. Read More

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http://dx.doi.org/10.1055/a-0655-7103DOI Listing
November 2018
4 Reads

Pyoderma Gangrenosum Following Carpal Tunnel Release: A Case Report.

JBJS Case Connect 2018 Oct-Dec;8(4):e91

Department of Orthopaedic Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.

Case: A 51-year-old woman with diabetes developed wound complications consistent with presumed infection 5 days after undergoing a carpal tunnel release. Despite multiple debridements, the wounds continued to necrose and deteriorate. A diagnosis of pyoderma gangrenosum eventually was made, and the condition improved with the administration of systemic corticosteroids. Read More

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http://dx.doi.org/10.2106/JBJS.CC.18.00116DOI Listing
November 2018
1 Read

Pyoderma Gangrenosum and Extensive Aseptic Chest Wall Abscess in a Patient with Inflammatory Bowel Disease.

Isr Med Assoc J 2018 Nov;20(11):712-713

Department of Medicine A, Rabin Medical Center (Beilinson Campus), Petah Tikva, Israel.

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November 2018
13 Reads

Successful treatment of pyoderma gangrenosum with concomitant immunoglobulin A nephropathy: A case report and review of literature.

World J Clin Cases 2018 Nov;6(13):703-706

Cerebrovascular Disease Center, Gansu Provincial Hospital, Lanzhou 730000, Gansu Province, China.

Pyoderma gangrenosum (PG) is an uncommon ulcerative cutaneous condition of an unknown etiology and is often associated with immune diseases. However, PG rarely shows visceral involvement, especially in the kidney. A 20-year-old female presented with pedal edema and skin ulceration of both lower limbs. Read More

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http://dx.doi.org/10.12998/wjcc.v6.i13.703DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232568PMC
November 2018
1 Read

A rare skin condition masquerading as a serious wound infection.

J Surg Case Rep 2018 Nov 5;2018(11):rjy299. Epub 2018 Nov 5.

Medical Oncology, St John of God Subiaco Hospital, Subiaco, Western Australia.

Pyoderma gangrenosum is a rare, serious and commonly missed condition that can effect post-operative surgical patients. The condition is commonly misdiagnosed as a wound infection, with subsequent inappropriate antibiotic therapy and wound debridement. We present the case of a 46-year-old patient who suffered this delayed diagnosis and multiple unnecessary interventions. Read More

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http://dx.doi.org/10.1093/jscr/rjy299DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215978PMC
November 2018
2 Reads

A case of rituximab-induced pyoderma gangrenosum.

JAAD Case Rep 2018 Nov 29;4(10):979-981. Epub 2018 Oct 29.

Schulich School of Medicine and Dentistry, London, Canada.

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http://dx.doi.org/10.1016/j.jdcr.2018.09.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214884PMC
November 2018
1 Read