4,787 results match your criteria Pyelonephritis Chronic


[Long-term monitoring of leukocyturia and bacteriuria after acute obstructive pyelonephritis].

Urologiia 2018 Oct(4):44-48

RostSMU of Minzdrav of Russia, Rostov on Don, Russia.

The generally accepted standard of antibiotic therapy aimed at causative agent does not exclude the risk of acute obstructive pyelonephritis (AOP) to become chronic after the end of antibiotic therapy, resulting in a high incidence of relapses. To assess the outcomes of the AOP, we undertook a prospective clinical trial. MATERIALS AND METHODS: The study comprised 51 consistently selected patients (12 men and 39 women) with AOP occurred as a result of unilateral ureteric calculus obstruction. Read More

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October 2018
1 Read

Endocan as a marker of microvascular inflammation in kidney transplant recipients.

Sci Rep 2019 Feb 12;9(1):1854. Epub 2019 Feb 12.

Division of Nephrology, Department of Internal Medicine, Kyung Hee University, Seoul, South Korea.

Endocan is a water-soluble proteoglycan exclusively secreted by vascular endothelium. Endocan levels may be elevated in kidney transplant recipients experiencing antibody-mediated rejection (ABMR), which is characterized by vascular inflammation in transplanted kidney. We evaluated the clinical relevance of endocan as markers of microvascular inflammation in patients who underwent kidney transplantation. Read More

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http://dx.doi.org/10.1038/s41598-018-37975-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372712PMC
February 2019
2 Reads

[Some epidemiological aspects of urinary tract infections in Altai regional hospital for veterans of wars].

Urologiia 2018 Dec(6):76-79

FGBOU VG ASMU of the Ministry of Health of the Russian Federation, Barnaul, Russia.

Introduction: Urinary tract infections (UTIs) are among the most common infectious diseases in outpatient and inpatient practice.

Aim: to analyze some epidemiological aspects of UTIs in large hospitals of the Altai Territory (AK) for 2007-2017 yy.

Materials And Methods: a retrospective analysis of UTI incidence, including acute and chronic pyelonephritis, acute and chronic cystitis in the AK for 2007-2017, as well as in large medical organizations (MO) AK (KGBUZ "Altai regional hospital for war veterans" and KGBUZ. Read More

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December 2018
1 Read

[The changes in urine microflora in patients with urinary stone disease].

Urologiia 2018 Dec(6):32-36

Urologic Clinic and Department of Urology.

Introduction: Since the results of treatment of chronic pyelonephritis (CP) depend on timely and rationally selected targeted antibiotic therapy, when choosing a treatment regimen, it is necessary to rely on the local data obtained by monitoring the state of microflora in a particular hospital.

Aim: to monitor the changes in urine microflora in patients with urinary stone disease.

Materials And Methods: A total of 598 isolated bacteria and yeast-like fungi from patients with urinary stone disease who were treated in the Department of Urology during different time periods (1997-1999, 2010-2014 and 2015-2017 yy) were analyzed. Read More

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December 2018
1 Read

[Features of the proteome of the urine in chronic pyelonephritis.]

Klin Lab Diagn 2018 ;63(7):397-402

Institute of biomedical problems RAN, Russia, 123007, Moscow.

Clinical observation and examination of 12 patients with chronic pyelonephritis (CPN) were performed. The first group (GI) included patients with exacerbation of the disease. In the comparison group (GII)- the same patients after 1. Read More

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http://dx.doi.org/10.18821/0869-2084-2018-63-7-397-402DOI Listing
January 2018
2 Reads

Bear Paw Sign: Xanthogranulomatous Pyelonephritis.

J Radiol Case Rep 2018 Nov 30;12(11):18-24. Epub 2018 Nov 30.

Department of Urology, Hospital Universitario Sanitas La Moraleja, Universidad Francisco de Vitoria, Madrid, Spain.

Xanthogranulomatous pyelonephritis is a rare form of chronic pyelonephritis in which the involved areas of the kidneys are destroyed and replaced by foam cells. It usually occurs in immunocompromised middle-aged females with ureteral obstruction or chronic urinary tract infection induced by the formation of renal stones. We herein report the case of a 44-year-old woman, with a history of left kidney staghorn calculi and recurrent urinary tract infections. Read More

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http://dx.doi.org/10.3941/jrcr.v12i11.3415DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312122PMC
November 2018
1 Read

Acute Pyelonephritis: A Single-center Experience.

Indian J Nephrol 2018 Nov-Dec;28(6):454-461

Department of Nephrology, Institute of Nephro Urology, Victoria Hospital Campus, Bengaluru, Karnataka, India.

Acute pyelonephritis (APN), although a common clinical entity, still not much is known about the clinical profile in the Indian scenario. We prospectively collected clinical, biochemical, and radiological data of patients hospitalized with a diagnosis of APN from March 2014 to June 2016. A total of 296 cases were included in the study. Read More

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http://www.indianjnephrol.org/text.asp?2018/28/6/454/244252
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http://dx.doi.org/10.4103/ijn.IJN_219_16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6309380PMC
January 2019
5 Reads

[Activity of α2-adrenergic and PAF receptors of platelets as risk factor of acute pyelonephritis during urolithiasis in eldery women.]

Authors:
E F Barinov

Adv Gerontol 2018 ;31(5):711-716

M.Gorkiy Donetsk national medical university, 16, pr. Il'yicha, Donetsk 83003, Ukraine; e-mail:

The aim of the study is to identify possible mechanisms that could provoke a recurrence of chronic obstructive pyelonephritis (COP) in eldery women, thus to find out - why age and sex can be risk factors for acute pyelonephritis in urolithiasis. The results of 43 women over 65 years of age (mean age 71±1,5 years) are presented in study. The 26 patients were examined in remission phase of COP; 17 patients were examined in recurrence phase. Read More

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January 2018
3 Reads

[Features of urolithiasis in patients of advanced and senile age.]

Adv Gerontol 2018 ;31(3):368-373

Saint-Petersburg Institute of Bioregulation and Gerontology, 3, pr. Dinamo, St. Petersburg 197110, Russian Federation; e-mail:

There were 105 patients of different gender of elderly and senile age with urolithiasis. The entire contingent of patients with ICD was divided into 2 groups: the main group (55 people aged 61-85 years) and the comparison group (50 people aged 40-60). All patients went throught a general clinical examination: a detailed history of the anamnesis, an objective examination, laboratory and instrumental methods of investigation. Read More

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January 2018
1 Read

Isolated Neurogenic Bladder Associated With Human T-Lymphotropic Virus Type 1 Infection in a Renal Transplant Patient From Central Australia: A Case Report.

Transplant Proc 2018 Dec 7;50(10):3940-3942. Epub 2018 Sep 7.

Central Australian Renal Services, Alice Springs Hospital, Northern Territory, Australia.

Background: Human T-lymphotropic virus type 1 (HTLV-1) is endemic amongst the Aborigines of the Northern Territory of Australia. HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP) has been associated with this infection. In general population, isolated neurogenic bladder dysfunction in HTLV-1-infected individuals without HAM/TSP has been reported, and the HTLV-1 proviral load has been found to be higher in such patients compared with asymptomatic carriers. Read More

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http://dx.doi.org/10.1016/j.transproceed.2018.08.031DOI Listing
December 2018
1 Read

[The features of the pathologic changes in chronic oxalate stone disease after 16 week of experimental phase].

Urologiia 2018 Dec(5):13-15

FGBOU VO Altai State Medical University of the Ministry of Health of Russia, Barnaul, Russia.

Aim: to study the pathologic features of chronic oxalate stone disease.

Materials And Methods: a model of the experimental oxalate stone disease was done in rats that drank the 1% ethylene glycol solution for 16 weeks. The pathologic analysis of the rats kidneys was done. Read More

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December 2018
1 Read

Early start of clean intermittent catheterization versus expectant management in children with spina bifida.

J Pediatr Surg 2019 Feb 5;54(2):322-325. Epub 2018 Nov 5.

Department of Paediatric Urology, Royal Belfast Hospital for Sick Children, Northern Ireland.

Purpose: We instituted early clean intermittent catheterization (CIC) in 1997 for all newborn infants with spina bifida (SB). We compared this group to a historical group managed expectantly to see if early catheterization was associated with a reduction in renal scar rate as determined by DMSA scanning.

Methods: Data were studied retrospectively on all infants with SB over a recent 13-year period who were treated with early universal CIC in a regional pediatric urology department. Read More

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http://dx.doi.org/10.1016/j.jpedsurg.2018.10.096DOI Listing
February 2019
1 Read

Emerging Infection in Indian Neonatal Intensive Care Units: A Case Report.

Antibiotics (Basel) 2018 Dec 14;7(4). Epub 2018 Dec 14.

Department of Pediatrics, RD Gardi Medical College, Ujjain 456006, India.

Antibiotic-resistant pathogens and nosocomial infections constitute common and serious problems for neonates admitted to neonatal intensive care units worldwide. is a non-lactose-fermenting, gram-negative, health care-associated pathogen (HCAP). It is ubiquitous and intrinsically resistant to several antibiotics. Read More

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http://www.mdpi.com/2079-6382/7/4/109
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http://dx.doi.org/10.3390/antibiotics7040109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316706PMC
December 2018
9 Reads

Risk factors for positive urine cultures in cats with subcutaneous ureteral bypass and ureteral stents (2010-2016).

J Vet Intern Med 2019 Jan 3;33(1):178-183. Epub 2018 Dec 3.

Department of Veterinary Surgical and Radiological Sciences, University of California, Davis, California.

Background: Ureteral stent and subcutaneous ureteral bypass (SUB) placement are commonly used for managing ureteral obstructions. Urinary tract infection (UTI) is a recognized complication.

Objectives: To determine postoperative incidence of positive urine cultures in cats undergoing ureteral stent and SUB placement and to identify risk factors associated with positive urine cultures. Read More

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http://dx.doi.org/10.1111/jvim.15343DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335572PMC
January 2019
1 Read

Descriptive Epidemiology of Acute Pyelonephritis in Korea, 2010-2014: Population-based Study.

J Korean Med Sci 2018 Dec 12;33(49):e310. Epub 2018 Nov 12.

Department of Internal Medicine, College of Medicine, Hanyang University, Seoul, Korea.

Background: Acute pyelonephritis (APN) is one of the most common community-acquired bacterial infections. Recent increases of antimicrobial resistance in urinary pathogens might have changed the other epidemiologic characteristics of APN. The objective of this study was to describe the current epidemiology of APN in Korea, using the entire population. Read More

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https://synapse.koreamed.org/DOIx.php?id=10.3346/jkms.2018.3
Publisher Site
http://dx.doi.org/10.3346/jkms.2018.33.e310DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262185PMC
December 2018
20 Reads

EFFECTIVENESS OF NONALCOHOLIC STEATOHEPATITIS CORRECTION ON THE BAСKGROUND OF OBESITY WITH CONCOMITANT CHRONIC KIDNEY DISEASE.

Georgian Med News 2018 Oct(283):76-80

Higher educational establishment of Ukraine «Bukovinian State Medical University», Chernivtsi, Ukraine.

The article presents a theoretical generalization of the research results the effectiveness of heparisin on the state of the carbohydrate-protein components of the extracellular matrix of connective tissue in liver in patients with non-alcoholic steatohepatitis with obesity I-II degree and chronic kidney disease І-ІІ stage. The purpose of the study is to find out the effectiveness of heparisin (glycyrizine 40 mg, glycine 400 mg, L-cysteine hydrochloride 20 mg) on the state of the carbohydrate-protein components of the extracellular matrix in connective tissue of the liver in patients with non-alcoholic steatohepatitis (NASH) with obesity I-II degree and chronic kidney disease (CKD) І-ІІ stage. 98 patients with NASH on the background of obesity of the I-II degree were examined, including: 52 patients with NASH (I group) (without accompanying CKD), 46 patients with NASH with comorbid CKD І-ІІ stage (II group). Read More

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October 2018
1 Read

Adrenal crisis presented as acute onset of hypercalcemia and hyponatremia triggered by acute pyelonephritis in a patient with partial hypopituitarism and pre-dialysis chronic kidney disease.

CEN Case Rep 2018 Nov 19. Epub 2018 Nov 19.

Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-Ku, Fukuoka, 812-8582, Japan.

A 57-year-old woman with pre-dialysis chronic kidney disease (CKD) was hospitalized because of fever and fatigue. On admission, increased inflammatory response and pyuria with bacteriuria were observed. Pyelonephritis was successfully treated with antibiotics, whereas her fatigue continued and she developed progressive hypercalcemia and hyponatremia; serum sodium level, 116 mEq/L and corrected serum calcium level, 13. Read More

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http://link.springer.com/10.1007/s13730-018-0371-9
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http://dx.doi.org/10.1007/s13730-018-0371-9DOI Listing
November 2018
17 Reads

Xanthogranulomatous pyelonephritis in adults: clinical, biological, radiological and therapeutic main findings in diffuse and focal forms. About 42 cases.

Tunis Med 2018 Aug - Sep;96(8-09):495-500

Introduction: Xanthogranulomatous pyelonephritis (XGPN) is a particular form of chronic renal suppuration characterized by the destruction of renal parenchyma and its replacement by a granulomatous tissue containing xanthomatous cells.

Objective: To report and describe the main clinical, biological, radiological and therapeutic aspects of xanthogranulomatous pyelonephritis in adults in focal and diffuse forms.

Methods: This was a monocentric retrospective study involving 42 cases of XGPN operated and histologically confirmed between 2005 and 2015. Read More

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November 2018
20 Reads

[The role of modification of innate immunity in development of premature labore].

Biomed Khim 2018 Sep;64(5):439-443

Research Institute of Obstetrics and Pediatrics, Rostov State Medical University, Ministry of Health of Russia, Rostov-on-Don, Russia.

To clarify the role of the infectious factor in the development of premature birth (PB) in women in serum, the content of TLR-4, the p65 subunit of the nuclear factor NF-kB, the cytokine TNF-a and the activity of PLA2 (phospholipase A2) were determinated by the enzyme immunoassay was studied. The profile of bioregulators in women with premature births was characterized by a high content of TLR-4, TNF-a and an increase in PLA2 activity and a decrease in the activity of the p65 subunit of NF-kB. 89 women aged 20-39 years were examined at 34-40 weeks gestation. Read More

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http://dx.doi.org/10.18097/PBMC20186405439DOI Listing
September 2018
3 Reads

Xanthogranulomatous pyelonephritis presenting as a left-sided pleural effusion.

Respirol Case Rep 2018 Dec 21;6(9):e00377. Epub 2018 Oct 21.

Department of Respiratory Medicine Monash Medical Centre Melbourne Australia.

Xanthogranulomatous pyelonephritis (XGP) is a rare chronic granulomatous process that affects the kidneys. It is usually associated with longstanding urinary tract infections and obstruction. Patients suffering from XGP typically present with undifferentiated symptoms, including abdominal pain, weight loss, and intermittent fevers. Read More

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http://dx.doi.org/10.1002/rcr2.377DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6196130PMC
December 2018
2 Reads

Management of acute pyelonephritis.

Tunis Med 2018 Jan;96(1):42-47

Introduction: Acute pyelonephritis (APN) results from bacterial invasion of the renal parenchyma. The aim of this study was to investigate the epidemiological, clinico-biological, therapeutic and evolutionary APN and to identify the risk factors of this renal disease.

Methods: We conducted a retrospective and descriptive study, over a period of 37 years (1977-2014), including 43 patients with APN, hospitalized in our Department. Read More

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January 2018
12 Reads

Idiopathic renal replacement lipomatosis: A diagnostic and therapeutic challenge.

Turk J Surg 2018 3;34(3):250-252. Epub 2018 Jan 3.

Department of Pathology, Shri Mahalaxmi Memorial Hospital, Sirsi, India.

Renal replacement lipomatosis is a rare benign renal disorder where the renal parenchyma is replaced by mature fatty tissue. It poses a diagnostic challenge to the clinicians due to an unusual presentation and clinical features. The disease usually presents in middle age with vague pain in the affected flank and variable urological symptoms. Read More

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http://dx.doi.org/10.5152/turkjsurg.2017.3387DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173602PMC
January 2018
2 Reads

Crystalluria and Chronic Kidney Disease.

Authors:
Samuel M Cohen

Toxicol Pathol 2018 Dec 1;46(8):949-955. Epub 2018 Oct 1.

1 Havlik-Wall Professor of Oncology, Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska, USA.

Crystalluria can involve the kidney and lower urinary tract, can produce acute and chronic effects, and occurs in all mammalian species. Most commonly urinary crystals contain calcium. Numerous other endogenous and exogenous substances can produce crystalluria. Read More

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http://dx.doi.org/10.1177/0192623318800711DOI Listing
December 2018
10 Reads

Clinical Effects of Polymyxin B Hemoperfusion in Patients With Septic Shock Caused by Urinary Tract Infection.

Ther Apher Dial 2019 Feb 12;23(1):80-85. Epub 2018 Sep 12.

Morioka Yuai Hospital, Iwate, Japan.

Direct hemoperfusion with polymyxin B-immobilized fiber (PMX-DHP) has been widely used for severe sepsis and septic shock. However, data are limited regarding the clinical experience and efficacy of PMX-DHP for septic shock resulting from urinary tract infection (UTI). At our institution, 15 patients with septic shock resulting from a UTI received PMX-DHP from January 2013 to July 2017. Read More

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http://dx.doi.org/10.1111/1744-9987.12746DOI Listing
February 2019
10 Reads

Ultrasound and color Doppler applications in chronic kidney disease.

J Nephrol 2018 Dec 6;31(6):863-879. Epub 2018 Sep 6.

Sant'Anna School of Advanced Studies, Department of Internal Medicine, University of Pisa, Pisa, Italy.

Chronic kidney disease (CKD) includes all clinical features and complications during the progression of various kidney conditions towards end-stage renal disease (ESRD). These conditions include immune and inflammatory disease such as: primary and hepatitis C virus (HCV)-related glomerulonephritis; infectious disease such as pyelonephritis with or without reflux and tuberculosis; vascular disease such as chronic ischemic nephropathy; hereditary and congenital disease such as polycystic disease and congenital cystic dysplasia; metabolic disease including diabetes and hyperuricemia; and systemic disease (collagen disease, vasculitis, myeloma). During the progression of CKD, ultrasound imaging and color Doppler imaging (US-CDI) can differentiate the etiology of the renal damage in only 50-70% of cases. Read More

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http://link.springer.com/10.1007/s40620-018-0531-1
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http://dx.doi.org/10.1007/s40620-018-0531-1DOI Listing
December 2018
8 Reads

Autosomal Dominant Polycystic Kidney Disease with Emphysematous Polycystic Renal Infection That Required Surgical Treatment.

Intern Med 2019 Jan 24;58(1):85-89. Epub 2018 Aug 24.

Department of Medicine, Kidney Center, Tokyo Women's Medical University, Japan.

We encountered a patient with autosomal dominant polycystic kidney disease (ADPKD) complicated with emphysematous polycystic renal infection (EPRI). A 44-year-old woman visited our hospital for a fever, appetite loss, and gross hematuria. Because the patient was suffering from end-stage renal disease (ESRD), she was immediately hospitalized for hemodialysis. Read More

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http://dx.doi.org/10.2169/internalmedicine.1257-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367087PMC
January 2019
13 Reads

[Xanthogranulonatous pyelonephritis: report of 5 cases].

Beijing Da Xue Xue Bao Yi Xue Ban 2018 Aug;50(4):743-746

Department of diagnostic Ultrasound,d HospPeking University Thirital 100191, China.

Xanthogranulomatous pyelonephritis (XGP) is an unusual form of chronic pyelonephritis in which the renal parenchyma is destroyed and replaced by lipid-laden foamy macrophages. It usually affects middle-aged women with a history of recurrent urinary tract infection, diabetes, or kidney stones. The inflammatory process is usually diffuse and can extend beyond the kidney. Read More

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August 2018
19 Reads

Urinothorax Caused by Xanthogranulomatous Pyelonephritis.

Case Rep Pulmonol 2018 14;2018:7976839. Epub 2018 Jun 14.

Department of Pulmonary Medicine, Joan C. Edwards School of Medicine, Marshall University, Huntington, West Virginia 25701, USA.

Xanthogranulomatous pyelonephritis is a rare form of chronic pyelonephritis that generally afflicts middle-aged women with a history of recurrent urinary tract infections. Its pathogenesis generally involves calculus obstructive uropathy and its histopathology is characterized by replacement of the renal parenchyma with lipid filled macrophages. This often manifests as an enlarged, nonfunctioning kidney that may be complicated by abscess or fistula. Read More

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https://www.hindawi.com/journals/cripu/2018/7976839/
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http://dx.doi.org/10.1155/2018/7976839DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022338PMC
June 2018
5 Reads

Impact of social deprivation on length of stay for common infectious diseases in two French university-affiliated general pediatric departments.

Arch Pediatr 2018 Aug 21;25(6):359-364. Epub 2018 Jul 21.

Inserm, ECEVE, U1123, 10, boulevard de Verdun, 75010 Paris, France; Université Paris Diderot, Sorbonne Paris Cité, 10, boulevard de Verdun, 75010 Paris, France; URC Eco Île-de-France, DRCD, Assistance publique-Hôpitaux de Paris, Hôtel Dieu, 1, place du Parvis-de-Notre-Dame, 75004 Paris, France.

Background: Adult deprived patients consume more healthcare resources than others, particularly in terms of increased length of stay (LOS) and costs. Very few pediatric studies have focused on LOS, although the effect of deprivation could be greater in children due to the vulnerability of this population. Our objective was to compare LOS between deprived and nondeprived children hospitalized for acute infectious diseases in two university-affiliated pediatric departments located in a low-income area of northern Paris. Read More

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http://dx.doi.org/10.1016/j.arcped.2018.06.003DOI Listing
August 2018
3 Reads

Studies on biofilm formation and virulence factors associated with uropathogenic Escherichia coli isolated from patient with acute pyelonephritis.

Pathophysiology 2018 Dec 19;25(4):381-387. Epub 2018 Jul 19.

School of Biosciences, Mahatma Gandhi University, Priyadarshini Hills, Kottayam, Kerala, India. Electronic address:

The current study aims to the detection of pathogenic potential and virulence factor identification of uropathogenic Escherichia coli BRL-17 isolated from patients urine. The organism was isolated from the patient with chronic pyelonephritis. The identification of organism was done by analyzing gram staining, biochemical, 16S rDNA analysis, Raman microscopy and SEM analysis. Read More

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http://dx.doi.org/10.1016/j.pathophys.2018.07.004DOI Listing
December 2018
3 Reads

Immunohistochemical characteristics of renomedullary interstitial cell tumor: a study of 41 tumors with emphasis on differential diagnosis of mesenchymal neoplasms.

Hum Pathol 2018 Dec 18;82:46-50. Epub 2018 Jul 18.

Department of Pathology and Laboratory Medicine, Henry Ford Health System, Detroit, MI 48202, USA. Electronic address:

Renomedullary interstitial cell tumors (RMICTs) are almost always incidentally identified either at autopsy or upon resection of the kidney for other reasons. However, rare cases that are large, resulting in a clinical mass, have been reported. The immunohistochemical phenotype of usual, incidental RMICT using modern soft tissue tumor markers is largely unknown, however, providing little information to aid in classification of larger or atypical tumors. Read More

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http://dx.doi.org/10.1016/j.humpath.2018.07.010DOI Listing
December 2018
27 Reads

Therapeutic effects of 5,2'-dibromo-2,4',5'-trihydroxydiphenylmethanone (LM49) in an experimental rat model of acute pyelonephritis by immunomodulation and anti-inflammation.

Int Immunopharmacol 2018 Sep 11;62:155-164. Epub 2018 Jul 11.

Shanxi Province Academy of Traditional Chinese Medicine, Taiyuan 030012, China.

Antibiotics are still the primary therapy for acute pyelonephritis (APN); rarely, natural polyphenols are also used. LM49 is a novel marine bromophenol derivative displaying strong anti-inflammatory effects. We investigated the therapeutic efficacy of LM49 in an experimental rat model of APN. Read More

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http://dx.doi.org/10.1016/j.intimp.2018.07.001DOI Listing
September 2018
10 Reads
2.470 Impact Factor

Pyeloduodenal Fistula in Xanthogranulomatous Pyelonephritis: A Series of Two Cases.

Perm J 2018 06;22

Surgeon in the Division of Transplant Surgery and the Division of Acute Care Surgery and Trauma at Memorial Regional Hospital in Hollywood, FL.

Xanthogranulomatous inflammation, characterized by destruction and replacement of tissues with chronic inflammatory cells, including foamy histiocytes and hemosiderin-laden macrophages, is uncommon. In patients with xanthogranulomatous pyelonephritis, inflammation may extend from the kidney to the overlying duodenum, creating a pyeloduodenal fistula that further complicates medical and surgical management. We present two cases with recurrent kidney infections who each ultimately received a nephrectomy and repair of their duodenal fistula. Read More

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http://dx.doi.org/10.7812/TPP/17-150DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6045498PMC
June 2018
9 Reads

The pathological evaluation of nonneoplastic kidney disorder in tumor nephrectomy specimens.

Saudi J Kidney Dis Transpl 2018 May-Jun;29(3):586-590

Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran.

Renal cell carcinoma (RCC) comprises 2%-3% of all visceral and 80%-85% of all adult kidney malignancies. Nephrectomy is the treatment of choice for renal tumors. The accurate pathological evaluation of nonneoplastic renal parenchyma in nephrectomy specimens is important for subsequent management. Read More

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http://dx.doi.org/10.4103/1319-2442.235170DOI Listing
July 2018
19 Reads

Interpretation of Kidney Biopsy in Indian Patients Older than 60 Years: A Tertiary Care Experience.

Indian J Nephrol 2018 May-Jun;28(3):198-202

Department of Nephrology, Madras Medical Mission, Chennai, Tamil Nadu, India.

The adult population above the age of 60 years has significantly increased in India, with a life expectancy of 68.4 years in 2016. Data regarding the renal histopathology in these patients are scarce though the number of native kidney biopsies done in this subset of population is increasing. Read More

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http://dx.doi.org/10.4103/ijn.IJN_158_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998713PMC
July 2018
9 Reads

[Renal tumor or pseudotumoral xanthogranulomatous pyelonephritis].

Pan Afr Med J 2018 24;29:67. Epub 2018 Jan 24.

Service de Radiologie, Centre Hospitalier Provincial, Taounate, Maroc.

We here report the case of a 55 year-old man presenting with right renal colic and with a history of intermittent lower back disorders. At the time of admission, clinical examination showed lower back pain on contact. Renal ultrasound objectified heterogeneous mass at the lower pole of the right kidney with dilation of lower calyx groups. Read More

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http://dx.doi.org/10.11604/pamj.2018.29.67.14611DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987130PMC
June 2018
5 Reads

Primary Squamous Cell Carcinoma of Renal Pelvis in Non-Functioning Kidneys.

J Coll Physicians Surg Pak 2018 Jun;28(6):S148-S150

Department of Urology, Haydarpasa Numune Research and Training Hospital, Istanbul, Turkey.

Primary renal pelvic squamous cell carcinomas comprise 0.5% of all renal neoplasms and are rare. The most common risk factor is nephrolithiasis. Read More

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http://dx.doi.org/10.29271/jcpsp.2018.06.S148DOI Listing
June 2018
1 Read

Proteflazid®: treatment of herpesvirus and mixed infections. Meta-analysis of clinical trials results.

Pol Merkur Lekarski 2018 May;44(263):236-247

Scientific and Manufacturing Company "Ecopharm" Ltd, Kyiv, Ukraine.

There is a meta-analysis of clinical trials results concerning the evaluation of efficiency of the drug Proteflazid® (drops) in the treatment of adult patients with herpesvirus and mixed infections.

Aim: Objective of the study: to evaluate the clinical efficacy of the drug Proteflazid® in a treatment of herpesvirus (HSV-1, HSV-2) and mixed infections in adults by meta-analysis of clinical trials.

Materials And Methods: In meta-analysis, 16 scientific sources with results of controlled studies with participation of 1336 patients over 18 y. Read More

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May 2018
4 Reads

Xantogranulomatous pyeloneprhritis in children.

Insights Imaging 2018 Oct 23;9(5):643-651. Epub 2018 May 23.

Pathology Department, Hospital Universitario y Politécnico La Fe Pediatric Imaging Section, Avenida Fernando Abril Martorell 106, 46026, Valencia, Spain.

Xanthogranulomatous pyelonephritis (XPN) is an unusual and severe form of chronic inflammatory lesion of the kidney, characterised by the destruction of the renal parenchyma and the presence of multinucleated giant cells and lipid-laden macrophages, inflammatory infiltration and intensive renal fibrosis. There are a few cases in the literature which describe the disease in children. The pathomechanism of XPN is poorly understood. Read More

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http://dx.doi.org/10.1007/s13244-018-0631-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206370PMC
October 2018
4 Reads

Case of perinephric abscess disguising as renal tumor.

Urol Case Rep 2018 May 1;18:35-37. Epub 2018 Mar 1.

Department of Urology, Faculty of Medicine, Indonesia University, Cipto Mangunkusumo Hospital, Jalan Diponegoro No. 71, Jakarta 10430, Indonesia.

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http://dx.doi.org/10.1016/j.eucr.2018.02.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5958932PMC
May 2018
4 Reads

Spontaneous perirenal hemorrhage (Wunderlich syndrome): An analysis of 28 cases.

Am J Emerg Med 2019 Jan 21;37(1):45-47. Epub 2018 Apr 21.

Department of Urology, Korea University College of Medicine, Seoul, Republic of Korea. Electronic address:

Introduction: This study aimed to analyze the characteristics, etiology, and treatment of a series of patients with spontaneous perirenal hemorrhage (Wunderlich syndrome [WS]).

Methods: We retrospectively reviewed the records of 26 patients hospitalized for WS in a tertiary urological center between 2011 and 2018. All patients were evaluated for perirenal hemorrhage observed on computed tomography (CT) in the emergency department. Read More

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http://dx.doi.org/10.1016/j.ajem.2018.04.045DOI Listing
January 2019
8 Reads

Prospective Study on Several Urinary Biomarkers as Indicators of Renal Damage in Children with CAKUT.

Eur J Pediatr Surg 2018 May 4. Epub 2018 May 4.

Pediatric Surgery Unit, University of Foggia, Foggia, Italy.

Purpose:  The aim of the study was to investigate urinary levels of monocyte chemotactic protein-1 (MCP-1), epidermal growth factor (EGF), β-2-microglobulin (β2M), and FAS-ligand (FAS-L) in children with congenital anomalies of kidney and urinary tract (CAKUT) disease at risk of developing glomerular hyperfiltration syndrome. For this reason, we selected patients with multicystic kidney, renal agenesia and renal hypodysplasia, or underwent single nephrectomy.

Materials And Methods:  This prospective, multicentric study was conducted in collaboration between the Pediatric Surgery Unit in Foggia and the Pediatric Nephrology Unit in Bari, Italy. Read More

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http://dx.doi.org/10.1055/s-0038-1646960DOI Listing
May 2018
7 Reads

Acute Kidney Injury in Pregnancy: The Changing Landscape for the 21st Century.

Kidney Int Rep 2018 Mar 2;3(2):247-257. Epub 2018 Feb 2.

Division of Nephrology, Department of Medicine, Jacobi Medical Center at Albert Einstein College of Medicine, Bronx, New York, USA.

Pregnancy-related acute kidney injury (Pr-AKI) remains a large public health problem, with decreasing incidences in developing countries but seemingly increasing incidences in the United States and Canada. These epidemiologic changes are reflective of the advances in medical and obstetric care, as well as changes in underlying maternal risk factors. The risk factors associated with advanced maternal age, such as hypertension, diabetes, chronic kidney disease, and those associated with reproductive technologies such as multiple gestations, are increasing. Read More

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http://dx.doi.org/10.1016/j.ekir.2018.01.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932309PMC
March 2018
11 Reads

Characterization of subclinical bacteriuria, bacterial cystitis, and pyelonephritis in dogs with chronic kidney disease.

J Am Vet Med Assoc 2018 May;252(10):1257-1262

OBJECTIVE To determine the prevalence of bacteriuria (ie, a positive microbial culture result for ≥ 1 urine sample) in dogs with chronic kidney disease (CKD) and characterize findings of subclinical bacteriuria (SBU), bacterial cystitis, or pyelonephritis in these patients. DESIGN Retrospective, observational study. ANIMALS 182 dogs. Read More

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http://dx.doi.org/10.2460/javma.252.10.1257DOI Listing
May 2018
5 Reads

INTENSITY OF THE ANTIOXIDANT PROTECTION SYSTEM AND OXIDATIVE STRESS FACTORS IN PATIENTS WITH NON-ALCOHOLIC STEATOHEPATITIS DEPENDING ON THE FORM OF CHRONIC KIDNEY DISEASE.

Georgian Med News 2018 Mar(276):71-76

Higher State Educational Institution of Ukraine "Bukovinian State Medical University" Chernivtsi, Ukraine.

The article presents a theoretical generalization of the research results the intensity of the antioxidant protection system and oxidative stress factors in patients with non-alcoholic steatohepatitis depending on the form of chronic kidney disease. The objective of the article - determining the pathogenetic role of the processes of antioxidant protection system in the development and interconnection mechanisms of non-alcoholic steatohepatitis (NASH) and obesity depending on the form and stage of chronic kidney disease (CKD). 177 patients were examined for this purpose, including: 35 patients with NASH with concomitant obesity of І-ІІ degree (1st group), 36 patients with NASH with accompanying obesity of І-ІІ degree and CKD І-ІІ stage: Chronic bilateral pyelonephritis in the phase of exacerbation (2A group), 35 patients with NASH on the background of obesity I-II st. Read More

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March 2018
4 Reads

Prostatitis, other genitourinary infections and prostate cancer risk: Influence of non-steroidal anti-inflammatory drugs? Results from the EPICAP study.

Int J Cancer 2018 Apr 26. Epub 2018 Apr 26.

Université Paris-Saclay, Université Paris-Sud, CESP (Center for Research in Epidemiology and Population Health), Inserm, Team Cancer and Environment, Villejuif, France.

Epidemiological studies have suggested that prostatitis may increase the risk of prostate cancer due to chronic inflammation. We studied the association between several genitourinary infections and the risk of prostate cancer based on data from the EPICAP study. EPICAP is a population-based case-control study conducted in the département of Hérault, France, between 2012 and 2014. Read More

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http://doi.wiley.com/10.1002/ijc.31565
Publisher Site
http://dx.doi.org/10.1002/ijc.31565DOI Listing
April 2018
6 Reads

Impact of different assumptions on estimates of childhood diseases obtained from health care data: A retrospective cohort study.

Pharmacoepidemiol Drug Saf 2018 Jun 24;27(6):612-620. Epub 2018 Apr 24.

University Medical Center Utrecht, Julius Center, The Netherlands.

Purpose: Accurate estimates of disease incidence in children are required to support pediatric drug development. Analysis of electronic health care records (EHR) may yield such estimates but pediatric-specific methods are lacking. We aimed to understand the impact of assumptions regarding duration of disease episode and length of run-in period on incidence estimates from EHRs. Read More

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http://dx.doi.org/10.1002/pds.4413DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001570PMC
June 2018
9 Reads

[Recurrent Upper Abdominal Pain].

Praxis (Bern 1994) 2018 Apr;107(9-10):551-553

2 Präsident SwW - Stiftung für medizinischen Wissenstransfer.

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http://dx.doi.org/10.1024/1661-8157/a002955DOI Listing
April 2018
3 Reads