18,656 results match your criteria Pyelonephritis Chronic


[Chikungunya, emerging disease in Latin America. Description of the first cases in Chile].

Rev Chilena Infectol 2018 Aug;35(4):413-419

Laboratorio de Infectología y Virología Molecular, Pontificia Universidad Católica de Chile, Chile.

Background: Chikungunya (CHIK) was introduced in The Americas in 2013, spreading rapidly. In 2014, the first imported case was diagnosed in Chile.

Aim: To identify patients with clinical suspicion of CHIK and describe their clinical and laboratory characteristics. Read More

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Renal and Splenic Infarction in a Patient with Familial Hypercholesterolemia and Previous Cerebral Infarction.

Am J Case Rep 2018 Dec 10;19:1463-1466. Epub 2018 Dec 10.

Department of Internal Medicine, Haga Teaching Hospital, Hague, Netherlands.

BACKGROUND This is a case report of a male patient who presented with a history of right flank pain based on renal infarction. Initially the symptoms were misdiagnosed as acute pyelonephritis. CASE REPORT A 47-year-old male with a history of familial hypercholesterolemia and cerebral infarction presented at the Emergency Department with a 3-day history of acute right-sided flank pain. Read More

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December 2018

BK virus nephropathy and multiorgan involvement in a child with heart transplantation
.

Clin Nephrol 2018 Dec 11. Epub 2018 Dec 11.

BK virus is a known cause of renal failure in kidney transplant recipients, but there is little data regarding its effect on native kidneys in heart transplant patients. Here, we describe the case of a child who underwent heart transplantation and was later diagnosed with BK virus with multiorgan involvement. This patient was diagnosed with dilated cardiomyopathy at 4 months of age and underwent heart transplantation at the age of 5 years. Read More

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December 2018

Zishenwan Decreases Kidney Damage in Recurrent Urinary Tract Infection through the Inhibition of Toll-Like Receptor 4 Signal.

Evid Based Complement Alternat Med 2018 5;2018:5968657. Epub 2018 Nov 5.

Suzhou Academy of Wumen Chinese Medicine, Suzhou 215000, China.

Objectives: To investigate the mechanism of the protective effect of Zishenwan on pyelonephritis rats.

Methods: In the rat model of pyelonephritis, protective effects of Zishenwan, the content of secretory immunoglobulin A (SIg A), and interleukins were detected by ELISA. The expressions of TLR4-NFB pathway were detected by Western blot in renal and urinary tract mucosa. Read More

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November 2018
1 Read

Risk factors for positive urine cultures in cats with subcutaneous ureteral bypass and ureteral stents (2010-2016).

J Vet Intern Med 2018 Dec 3. Epub 2018 Dec 3.

Department of Veterinary Surgical and Radiological Sciences, University of California, Davis, California.

Background: Ureteral stent and subcutaneous ureteral bypass (SUB) placement are commonly used for managing ureteral obstructions. Urinary tract infection (UTI) is a recognized complication.

Objectives: To determine postoperative incidence of positive urine cultures in cats undergoing ureteral stent and SUB placement and to identify risk factors associated with positive urine cultures. Read More

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December 2018

Evaluating Natural History and Follow Up Strategies for Non-obstructive Urolithiasis in Pediatric Population.

Front Pediatr 2018 16;6:353. Epub 2018 Nov 16.

Scott Department of Urology, Baylor College of Medicine, Houston, TX, United States.

While small non-obstructive stones in the adult population are usually observed with minimal follow-up, the same guidelines for management in the pediatric population have not been well-studied. We evaluate the clinical outcomes of small non-obstructing kidney stones in the pediatric population to better define the natural history of the disease. In this IRB-approved retrospective study, patients with a diagnosis of kidney stones from January 2011 to March 2017 were identified using ICD9 and ICD10 codes. Read More

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November 2018

Has the Incidence of Acute Pyelonephritis Increased in Korea? - Big Data as a Double-edged Sword.

Authors:
Jin-Hong Yoo

J Korean Med Sci 2018 Dec 15;33(49):e317. Epub 2018 Nov 15.

Division of Infectious Diseases, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea.

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December 2018

Descriptive Epidemiology of Acute Pyelonephritis in Korea, 2010-2014: Population-based Study.

J Korean Med Sci 2018 Dec 12;33(49):e310. Epub 2018 Nov 12.

Department of Internal Medicine, College of Medicine, Hanyang University, Seoul, Korea.

Background: Acute pyelonephritis (APN) is one of the most common community-acquired bacterial infections. Recent increases of antimicrobial resistance in urinary pathogens might have changed the other epidemiologic characteristics of APN. The objective of this study was to describe the current epidemiology of APN in Korea, using the entire population. Read More

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December 2018
1 Read

Isolation of a Capnophilic and an Extended-Spectrum-β-Lactamase-Producing Proteus mirabilis Isolate with Inability to Grow under pH-Indicator Dyes from the Urine of an Octogenarian Male-Patient with Acute Pyelonephritis.

Jpn J Infect Dis 2018 Nov 30. Epub 2018 Nov 30.

Department of Health and Medical Sciences, Shinshu University Graduate School of Medicine.

A capnophilic Gram-negative rod was recovered from the urine of an octogenarian male patient with acute pyelonephritis. The isolate also demonstrated to produce CTX-M-2-type- extended-spectrum-β-lactamase. Interestingly, the isolate failed to grow on modified Drigalski (BTB) and MacConkey agars even in the CO-enriched atmosphere. Read More

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November 2018

EFFECTIVENESS OF NONALCOHOLIC STEATOHEPATITIS CORRECTION ON THE BAСKGROUND OF OBESITY WITH CONCOMITANT CHRONIC KIDNEY DISEASE.

Georgian Med News 2018 Oct(283):76-80

Higher educational establishment of Ukraine «Bukovinian State Medical University», Chernivtsi, Ukraine.

The article presents a theoretical generalization of the research results the effectiveness of heparisin on the state of the carbohydrate-protein components of the extracellular matrix of connective tissue in liver in patients with non-alcoholic steatohepatitis with obesity I-II degree and chronic kidney disease І-ІІ stage. The purpose of the study is to find out the effectiveness of heparisin (glycyrizine 40 mg, glycine 400 mg, L-cysteine hydrochloride 20 mg) on the state of the carbohydrate-protein components of the extracellular matrix in connective tissue of the liver in patients with non-alcoholic steatohepatitis (NASH) with obesity I-II degree and chronic kidney disease (CKD) І-ІІ stage. 98 patients with NASH on the background of obesity of the I-II degree were examined, including: 52 patients with NASH (I group) (without accompanying CKD), 46 patients with NASH with comorbid CKD І-ІІ stage (II group). Read More

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October 2018

Vesicoureteral Reflux and Renal Scarring in Infants After the First Febrile Urinary Tract Infection.

Med Arch 2018 Oct;72(4):272-275

Clinic for Nuclear Medicine, Clinical Center University of Sarajevo, Sarajevo, Bosnia and Herzegovina.

Introduction: The objective of this research was to determine whether vesicoureteral reflux(VUR) was associated with evolution to renal scarring (RS) following a febrile urinary tract infection (UTI) in infants.

Materials And Methods: Our research included 100 infants, ages up to 1 year with a first febrile UTI. The diagnostic was based on results of: laboratory findings, ultrasonography (USG), voiding cystourethrography (VCUG) and initial and control renal scintigraphy (DMSA renal scan) withtechnetiumTcsuccimer (dimercaptosuccinic acid), to assess the acute pyelonephritis (APN), VUR and RS. Read More

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October 2018
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Bloodstream Infection due to Piperacillin/Tazobactam Non-Susceptible, Cephalosporin-Susceptible : A Missed Opportunity for De-Escalation of Therapy.

Antibiotics (Basel) 2018 Dec 1;7(4). Epub 2018 Dec 1.

School of Medicine, University of South Carolina, Columbia, SC 29209, USA.

An increasing number of reports describing isolates with piperacillin/tazobactam resistance, despite retained cephalosporin susceptibility, suggest further emergence of this phenotypic resistance pattern. In this report, a patient with metastatic breast cancer presented to medical care after two days of chills, nausea, vomiting, reduced oral intake, and generalized weakness. Blood and urine cultures grew as identified by rapid diagnostics multiplex PCR and MALDI-TOF, respectively. Read More

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December 2018

Hydronephrosis in a dairy calf: A diagnosis delayed by a clinician's Bayesian brain reasoning.

Can Vet J 2018 Oct;59(10):1062-1066

Département de sciences cliniques, Faculté de Médecine Vétérinaire (FMV), Université de Montréal, St-Hyacinthe, Québec J2S 2M2.

A 3-week-old female dairy calf was presented because of severe weakness and diarrhea. Physical examination and ultrasound findings lead to a tentative diagnosis of intestinal obstruction, although serum biochemistry suggested a primary renal disorder. Reassessment of ultrasound images allowed diagnosis of hydronephrosis that had been misdiagnosed probably because of the clinician's biased Bayesian reasoning. Read More

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October 2018

Cefiderocol versus imipenem-cilastatin for the treatment of complicated urinary tract infections caused by Gram-negative uropathogens: a phase 2, randomised, double-blind, non-inferiority trial.

Lancet Infect Dis 2018 Dec 25;18(12):1319-1328. Epub 2018 Oct 25.

Shionogi & Co Ltd, Osaka, Japan.

Background: Carbapenem-resistant Gram-negative bacteria represent the highest priority for addressing global antibiotic resistance. Cefiderocol (S-649266), a new siderophore cephalosporin, has broad activity against Enterobacteriaceae and non-fermenting bacteria, such as Pseudomonas aeruginosa and Acinetobacter baumannii, including carbapenem-resistant strains. We assessed the efficacy and safety of cefiderocol versus imipenem-cilastatin for the treatment of complicated urinary tract infection in patients at risk of multidrug-resistant Gram-negative infections. Read More

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December 2018
2 Reads

Pyelonephritis Due to Dual Infection in a Diabetic Patient.

J Assoc Physicians India 2018 May;66(5):101

Professor, Department of Medicine, All India Institute of Medical Sciences, New Delhi.

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Acquired Factor VII Deficiency in Association with Pyelonephritis.

J Assoc Physicians India 2018 May;66(5):97-98

Junior Resident, SGRD-IMSAR, Sri Amritsar, Punjab.

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Ureaplasma urealyticum pyelonephritis presenting with progressive dysuria, renal failure, and neurologic symptoms in an immunocompromised patient.

Transpl Infect Dis 2018 Nov 25:e13032. Epub 2018 Nov 25.

Division of Pediatric Infectious Diseases, Department of Pediatrics, Washington University School of Medicine, Saint Louis, Missouri.

Ureaplasma urealyticum is a bacterial species correlated with urethritis in healthy individuals and invasive infections in immunocompromised patients. We describe a 20-year-old female with a history of remote heart transplant on everolimus, mycophenolate, and rituximab presenting with progressive urinary tract symptoms, renal failure, and neurologic symptoms. An extensive workup ultimately identified U urealyticum infection, and the patient successfully recovered after a course of azithromycin and doxycycline. Read More

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November 2018
1 Read

Infectious and Inflammatory Diseases of the Urinary Tract: Role of MR Imaging.

Magn Reson Imaging Clin N Am 2019 Feb 29;27(1):59-75. Epub 2018 Oct 29.

Department of Radiology, Hospital Garcia de Orta, Av. Torrado da Silva, 2805-267 Almada, Portugal; Department of Radiology, Hospital da Luz, Estrada Nacional 10, km 37, Setúbal 2900-722, Portugal. Electronic address:

Urinary tract infection (UTI) is among the most common of bacterial infections. Imaging studies are only required in cases of complicated UTIs. Ultrasound remains the first-line imaging method; however, CT is the gold standard for evaluation of UTIs. Read More

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February 2019
4 Reads

Emerging Multidrug-Resistant Hybrid Pathotype Shiga Toxin-Producing Escherichia coli O80 and Related Strains of Clonal Complex 165, Europe.

Emerg Infect Dis 2018 Dec;24(12):2262-2269

Enterohemorrhagic Escherichia coli serogroup O80, involved in hemolytic uremic syndrome associated with extraintestinal infections, has emerged in France. We obtained circularized sequences of the O80 strain RDEx444, responsible for hemolytic uremic syndrome with bacteremia, and noncircularized sequences of 35 O80 E. coli isolated from humans and animals in Europe with or without Shiga toxin genes. Read More

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December 2018
6 Reads

Adrenal crisis presented as acute onset of hypercalcemia and hyponatremia triggered by acute pyelonephritis in a patient with partial hypopituitarism and pre-dialysis chronic kidney disease.

CEN Case Rep 2018 Nov 19. Epub 2018 Nov 19.

Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-Ku, Fukuoka, 812-8582, Japan.

A 57-year-old woman with pre-dialysis chronic kidney disease (CKD) was hospitalized because of fever and fatigue. On admission, increased inflammatory response and pyuria with bacteriuria were observed. Pyelonephritis was successfully treated with antibiotics, whereas her fatigue continued and she developed progressive hypercalcemia and hyponatremia; serum sodium level, 116 mEq/L and corrected serum calcium level, 13. Read More

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November 2018
6 Reads

Urinary Tract Infections.

Pediatr Clin North Am 2019 Feb;66(1):1-13

Nephrology Section, Nationwide Children's Hospital, 700 Children's Drive, Columbus, OH 43205, USA; Department of Pediatrics, Ohio State University School of Medicine, 700 Children's Drive, Columbus, OH 43210, USA; Center for Clinical and Translational Research, The Research Institute at Nationwide Children's Hospital, 700 Children's Drive, W308, Columbus, OH 43205, USA. Electronic address:

Urinary tract infection (UTI) is the second most common bacterial infection in children and is considered a public health threat given the mounting rates of antibiotic-resistance among uropathogens. This article highlights recent encouraging developments in UTI research. Further work is necessary to translate the discoveries into accessible, cost-effective technologies that will aid clinicians in real-time decision-making. Read More

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February 2019

Ultrasound screening for pyelectasis in pregnant women. Clinical necessity or "art for art's sake"?

Authors:
Piotr Szkodziak

J Ultrason 2018 ;18(73):152-157

3rd Department of Gynecology, Medical University of Lublin, Lublin, Poland.

Renal pelvicalyceal dilatation is caused by urine retention in the upper urinary tract. It is referred to as pyelectasis in medical literature. This term does not indicate the cause that leads to the dilatation of and urine retention in the renal pelvicalyceal system. Read More

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January 2018
7 Reads

A case of bilateral emphysematous pyelonephritis caused by Candida albicans.

J Infect Chemother 2018 Nov 15. Epub 2018 Nov 15.

Second Department of Internal Medicine, Nagasaki University, Nagasaki, Japan; Department of Respiratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.

Emphysematous pyelonephritis (EPN) is a life-threatening renal infection characterized by the formation of gas within the renal parenchyma and collecting duct system, as well as perinephric tissues. We herein report a case of bilateral EPN accompanied by the urinary tract infection caused by spherical growth of Candida albicans in a patient with underlying diabetes mellitus and prostate cancer. The diagnosis was assisted by computed tomography, urography, and gram staining. Read More

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November 2018
6 Reads

Mild encephalopathy/encephalitis with a reversible splenial lesion associated with acute pyelonephritis: A case report.

Neurologia 2018 Nov 13. Epub 2018 Nov 13.

Unidad de Neuropediatría, Departamento de Pediatría, Centro Hospitalar Vila Nova de Gaia, Vila Nova de Gaia, Portugal.

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November 2018
1 Read

Distribution of virulence genes and their association with antimicrobial resistance among uropathogenic Escherichia coli isolates from Iranian patients.

BMC Infect Dis 2018 Nov 15;18(1):572. Epub 2018 Nov 15.

Department of Urology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.

Background: Urinary tract infections (UTIs) are one of the most frequent diseases encountered by humans worldwide. The presence of multidrug-resistant (MDR) uropathogenic Escherichia coli (UPEC) harboring several virulence factors, is a major risk factor for inpatients. We sought to investigate the rate of antibiotic resistance and virulence-associated genes among the UPECs isolated from an Iranian symptomatic population. Read More

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November 2018
3 Reads

Xanthogranulomatous pyelonephritis in adults: clinical, biological, radiological and therapeutic main findings in diffuse and focal forms. About 42 cases.

Tunis Med 2018 Aug - Sep;96(8-09):495-500

Introduction: Xanthogranulomatous pyelonephritis (XGPN) is a particular form of chronic renal suppuration characterized by the destruction of renal parenchyma and its replacement by a granulomatous tissue containing xanthomatous cells.

Objective: To report and describe the main clinical, biological, radiological and therapeutic aspects of xanthogranulomatous pyelonephritis in adults in focal and diffuse forms.

Methods: This was a monocentric retrospective study involving 42 cases of XGPN operated and histologically confirmed between 2005 and 2015. Read More

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November 2018
9 Reads

High Pressure Balloon Dilatation of Primary Obstructive Megaureter in Children: A Multicenter Study.

Front Pediatr 2018 31;6:329. Epub 2018 Oct 31.

Department of Pediatric Surgery, University Teaching Hospital of Tours, Gatien de Clocheville Hospital, Tours, France.

We described the initial experience of four referral centers in the treatment of primary obstructive megaureter (POM) in children, by high-pressure balloon dilatation (HPBD) of the ureterovesical junction with double JJ stenting. We managed a retrospective multicenter study to assess its effectiveness in long-term. We reviewed the medical records of all children who underwent HPBD for POM that require surgical treatment from May 2012 to December 2017 in four different institutions. Read More

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October 2018

Late presentation of vesicoureteral reflux: An unusual cause of pyelonephritis in adults.

Int J Surg Case Rep 2018 Oct 29;53:238-241. Epub 2018 Oct 29.

Urology Department, Hospital de Braga, Braga, Portugal; Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal. Electronic address:

Introduction: Vesicoureteral reflux (VUR) corresponds to the reflux of urine from the bladder into the upper urinary system. It can be a congenital or an acquired anomaly and although its incidence is high in children it is uncommon in the adult life. One of its presentations in the adult population is the presence of recurrent Pyelonephritis. Read More

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October 2018
2 Reads

The efficacy and safety of tazobactam/ceftolozane in Japanese patients with uncomplicated pyelonephritis and complicated urinary tract infection.

J Infect Chemother 2018 Nov 9. Epub 2018 Nov 9.

Japan Development, MSD K.K., Tokyo, Japan. Electronic address:

We report efficacy and safety results for a combination of a novel cephalosporin class antibiotic and a β-Lactamase inhibitor, tazobactam/ceftolozane (1:2) at a dose of 1.5 g intravenously every 8 h in Japanese patients with uncomplicated pyelonephritis and complicated urinary tract infection. This study design was a nonrandomized, multicenter, open-label trial, and the treatment period was 7 days. Read More

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November 2018
3 Reads

Giant hydronephrosis presenting as acute pyelonephritis.

Br J Hosp Med (Lond) 2018 Nov;79(11):653

Consultant in Elderly Medicine, Acute Medical Unit, West Suffolk Hospital, West Suffolk NHS Foundation Trust, Bury St Edmunds IP33 2QZ.

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November 2018
1 Read

Preventive Effect of L-Carnitine on Scar Formation During Acute Pyelonephritis: A Randomized Placebo-Controlled Trial.

Am J Ther 2018 Oct 24. Epub 2018 Oct 24.

Department of Physiology, Applied Physiology Research, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.

Background: Urinary tract infection and pyelonephritis are clinical problems that frequently occur in children. Several factors are responsible for renal tissue injury, morbidity, and renal scarring after pyelonephritis. The aim of this study was to evaluate the preventive effect of L-carnitine on renal scarring in acute pyelonephritis. Read More

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October 2018
8 Reads

Insulin receptor signaling regulates renal collecting duct and intercalated cell antibacterial defenses.

J Clin Invest 2018 Dec 12;128(12):5634-5646. Epub 2018 Nov 12.

Center for Clinical and Translational Research, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio, USA.

People with diabetes mellitus have increased infection risk. With diabetes, urinary tract infection (UTI) is more common and has worse outcomes. Here, we investigate how diabetes and insulin resistance impact the kidney's innate defenses and urine sterility. Read More

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December 2018
3 Reads

Predictive factors of infectious complications in the postoperative of percutaneous nephrolithotomy.

Actas Urol Esp 2018 Nov 8. Epub 2018 Nov 8.

Servicio de Urología, Hospital Universitario y Politécnico La Fe, Valencia, España.

Objective: Infectious complications (IC) following percutaneous nephrolithotomy surgery (PCNL) can be life-threatening. Our objective was to analyse preoperative predictors of IC in PCNL.

Materials And Methods: A total of 203 patients who underwent PCNL were included in a prospective study between January 2013 and February 2016. Read More

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November 2018
1 Read

Emphysematous pyelonephritis in renal allograft related to antibody-mediated rejection: A case report and literature review.

Transpl Infect Dis 2018 Nov 9:e13026. Epub 2018 Nov 9.

Department of Transplant and Hepatobiliary Surgery, Henry Ford Hospital, Detroit, Michigan.

Emphysematous pyelonephritis (EPN) is a rare condition which can rapidly progress to sepsis and multiple organ failure with high mortality. We experienced a rare case of EPN in a renal allograft related to antibody-mediated rejection (AMR). The patient received a deceased donor kidney transplant due to end-stage renal disease secondary to diabetes mellitus. Read More

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November 2018
11 Reads

Emphysematous pyelonephritis and cystitis in a patient with uremia and anuria: A case report and literature review.

Medicine (Baltimore) 2018 Nov;97(45):e11272

Department of Nephrology, Qilu Hospital of Shandong University (Qingdao).

Introduction: Emphysematous pyelonephritis (EPN) or cystitis (EC) is a severe infection of the urinary tract with high mortality. EPN is uncommon among the patients of end stage of renal failure (ESRD) CASE PRESENTATION:: A 38-year-old male with uremia and anuria who was on hemodialysis was found to have gas formation in the bilateral pelvis, ureters, and urinary bladder by CT scan. The diagnosis was emphysematous pyelonephritis and cystitis. Read More

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November 2018
20 Reads

Review of Catheter-Associated Urinary Tract Infections and Urinary Tract Models.

J Healthc Eng 2018 14;2018:2986742. Epub 2018 Oct 14.

Bioscience Research Institute, Athlone Institute of Technology, Athlone, Ireland.

Catheter-associated urinary tract infections (CAUTIs) are one of the most common nosocomial infections and can lead to numerous medical complications from the mild catheter encrustation and bladder stones to the severe septicaemia, endotoxic shock, and pyelonephritis. Catheters are one of the most commonly used medical devices in the world and can be characterised as either indwelling (ID) or intermittent catheters (IC). The primary challenges in the use of IDs are biofilm formation and encrustation. Read More

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October 2018
7 Reads

Pharmacokinetics/Pharmacodynamics of Vaborbactam, a Novel Beta-lactamase Inhibitor, in Combination with Meropenem.

Antimicrob Agents Chemother 2018 Nov 5. Epub 2018 Nov 5.

The Medicines Company, San Diego, California, USA.

Vaborbactam is a novel beta-lactamase inhibitor with activity against important beta-lactamases, in particular, serine carbapenemases, and is currently approved in combination with meropenem as Vabomere™ for the treatment of complicated urinary tract infections, including pyelonephritis. This combination is highly active against Gram-negative pathogens, especially KPC-producing, carbapenem-resistant, The objective of these studies was to evaluate vaborbactam pharmacokinetics (PK) and pharmacodynamics (PD) relationships for efficacy in a neutropenic mouse thigh infection model and as well in an in vitro hollow fiber infection model, in combination with a fixed exposure of meropenem using KPC-containing strains of For both models, the meropenem dosage regimen was designed to simulate a 2 g dose administered every eight hours (q8h) by three hour infusion. Vaborbactam dosage regimens were designed to produce a wide range of 24 hour AUCs in the thigh infection model. Read More

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November 2018

A systematic review of single-dose aminoglycoside therapy for urinary tract infection: Is it time to resurrect an old strategy?

Antimicrob Agents Chemother 2018 Nov 5. Epub 2018 Nov 5.

Department of Pharmacy Services, St. Joseph's Hospital and Medical Center, Phoenix, AZ.

: Increasing bacterial resistance and poor patient adherence rates limit the effectiveness of conventional antibiotic therapies for urinary tract infection (UTI). The objective of this study was to investigate whether a single aminoglycoside dose adequately treated UTI.: A systematic search of PubMed/MEDLINE and Google Scholar databases was performed through September 2018 for English-language original research articles assessing the efficacy of one-time parenteral aminoglycoside as UTI monotherapy. Read More

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November 2018
11 Reads

ACR Appropriateness Criteria Acute Pyelonephritis.

J Am Coll Radiol 2018 Nov;15(11S):S232-S239

Specialty Chair, University of Alabama at Birmingham, Birmingham, Alabama.

Pyelonephritis refers to infection involving the renal parenchyma and renal pelvis. In most patients, uncomplicated pyelonephritis is diagnosed clinically and responds quickly to appropriate antibiotic treatment. If treatment is delayed, the patient is immunocompromised, or for other reasons, microabscesses that form during the acute phase of pyelonephritis may coalesce, forming a renal abscess. Read More

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November 2018
5 Reads
2.283 Impact Factor

Fever duration during treated urinary tract infections and development of permanent renal lesions.

Arch Dis Child 2018 Nov 2. Epub 2018 Nov 2.

Department of Nephrology, "P&A Kyriakou" Children's Hospital, Athens, Greece.

Objective: To assess the effect of the duration of fever after the initiation of treatment (FAT) of febrile urinary tract infections (UTI) on the development of permanent renal lesions based on dimercaptosuccinic acid (DMSA) scintigraphy findings. To evaluate the FAT contribution to permanent renal lesion formation in relation to fever before treatment initiation (FBT), the presence of vesicourinary reflux (VUR), age and severity of infection.

Methods: The inpatient records of 148 children (median age: 2. Read More

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November 2018
1 Read

Expanding the phenotype of COPA syndrome: a kindred with typical and atypical features.

J Med Genet 2018 Nov 1. Epub 2018 Nov 1.

Pulmonary Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA.

Background: Copa syndrome is a rare autosomal dominant disorder with abnormal intracellular vesicle trafficking. The objective of this work is to expand the knowledge about this disorder by delineating phenotypic features of an unreported COPA family.

Methods And Results: A heterozygous missense variant (c. Read More

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November 2018
6 Reads

Decreased antibiotic susceptibility of Enterobacteriaceae causing community-acquired urinary tract infections in French Amazonia.

Med Mal Infect 2018 Oct 29. Epub 2018 Oct 29.

Unité des maladies infectieuses et tropicales, centre hospitalier Andrée-Rosemon, 97300 Cayenne, French Guiana; Équipe EA 3593, écosystèmes amazoniens et pathologie tropicale, université de la Guyane, 97300 Cayenne, French Guiana. Electronic address:

Objectives: Urinary tract infections (UTIs) have rarely been studied in the Amazon region. We aimed to describe the epidemiology of bacteria causing UTIs in French Guiana.

Patients And Methods: We performed a monocenter retrospective study of adults consulting at the emergency department of Cayenne Hospital in 2014 with a diagnosis of UTI. Read More

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October 2018
1 Read

Outcomes of Kidney Transplant Recipients With Posttransplant Genitourinary Infectious Complications: A Single Center Study.

Exp Clin Transplant 2018 Oct 24. Epub 2018 Oct 24.

From the Department of Internal Medicine, Yale University, New Haven, Connecticut, USA.

Objectives: Long-term outcomes of kidney transplant recipients with postoperative genitourinary tract infections are not well characterized. In this single center retrospective study, we aimed to investigate the long-term effects of early posttransplant genitourinary infections under a protocol that included 1 month of antibiotic prophylaxis on graft failure and patient outcomes.

Materials And Methods: Electronic medical records of 1752 recipients of kidney-alone transplant between January 2000 and December 2008 were reviewed. Read More

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October 2018
1 Read

[The role of modification of innate immunity in development of premature labore].

Biomed Khim 2018 Sep;64(5):439-443

Research Institute of Obstetrics and Pediatrics, Rostov State Medical University, Ministry of Health of Russia, Rostov-on-Don, Russia.

To clarify the role of the infectious factor in the development of premature birth (PB) in women in serum, the content of TLR-4, the p65 subunit of the nuclear factor NF-kB, the cytokine TNF-a and the activity of PLA2 (phospholipase A2) were determinated by the enzyme immunoassay was studied. The profile of bioregulators in women with premature births was characterized by a high content of TLR-4, TNF-a and an increase in PLA2 activity and a decrease in the activity of the p65 subunit of NF-kB. 89 women aged 20-39 years were examined at 34-40 weeks gestation. Read More

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September 2018
2 Reads

Xanthogranulomatous pyelonephritis presenting as a left-sided pleural effusion.

Respirol Case Rep 2018 Dec 21;6(9):e00377. Epub 2018 Oct 21.

Department of Respiratory Medicine Monash Medical Centre Melbourne Australia.

Xanthogranulomatous pyelonephritis (XGP) is a rare chronic granulomatous process that affects the kidneys. It is usually associated with longstanding urinary tract infections and obstruction. Patients suffering from XGP typically present with undifferentiated symptoms, including abdominal pain, weight loss, and intermittent fevers. Read More

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December 2018
1 Read

Laparoscopic excision of an acquired ureteral diverticulum: A case report.

Asian J Endosc Surg 2018 Oct 24. Epub 2018 Oct 24.

Department of Urology, Kyoto University Hospital, Kyoto, Japan.

Ureteral diverticula, especially acquired diverticula, are rare. Surgery is indicated when a diverticulum is accompanied by complications such as stones, pyelonephritis, stenosis, and signs of malignancy. A 59-year-old woman visited our urology department with asymptomatic macrohematuria. Read More

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October 2018

[Widespread miliaria crystallina: about a case].

Pan Afr Med J 2018 28;30:69. Epub 2018 May 28.

Service de Dermatologie et Vénérologie, Centre Hospitalier Universitaire Ibn Sina, Faculté de Médecine et de Pharmacie, Université Mohammed V, Rabat, Maroc.

Prickly heat is a benign cutaneous manifestation due to the obstruction of the sweat ducts following excessive exposure to heat, humidity or hyperthermia. We report the case of a 70-year old diabetic female patient treated with insulin, hospitalized in the Intensive Care Unit due to acidocetosic coma secondary to pyelonephritis. The patient had diffuse clear vesicular lesions spread all over the body,(a) firm to palpation, on a healthy skin, suggesting miliaria crystallina. Read More

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October 2018

An assessment of potential unintended consequences following a national antimicrobial stewardship programme in England: an interrupted time series analysis.

Clin Infect Dis 2018 Oct 18. Epub 2018 Oct 18.

Dr Foster Unit, Department of Primary Care and Public Health, Imperial College London, London, United Kingdom.

Background: The 'Quality Premium' (QP) introduced in England in 2015 aimed to financially reward local healthcare commissioners for targeted reductions in primary care antibiotic prescribing. We aimed to evaluate possible unintended clinical outcomes related to this QP.

Methods: Using Clinical Practice Research Datalink and Hospital Episode Statistics datasets, we examined general practitioner (GP) consultations (visits) and emergency hospital admissions related to a series of pre-defined conditions of unintended consequences of reduced prescribing. Read More

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October 2018
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