1,040 results match your criteria Pulseless Electrical Activity


Outcomes of Cardiopulmonary Resuscitation of Oncologic Patients in Emergency Department.

J Coll Physicians Surg Pak 2022 May;32(5):658-661

Department of Family Medicine, School of Medicine, Eskisehir Osmangazi University, Eskisehir, Turkey.

Objective: To evaluate the outcomes of cardiopulmonary resuscitation (CPR) of oncological cases versus non-oncological admitted to the emergency department as out-of-hospital cardiac arrest (OHCA) or in-hospital cardiac arrest (IHCA).

Study Design: Descriptive study.

Place And Duration Of Study: Emergency Department (ED) of Eskisehir Osmangazi University Hospital, between January 2014 to January 2020. Read More

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Extracorporeal cardiopulmonary resuscitation in adult patients with out-of-hospital cardiac arrest: a retrospective large cohort multicenter study in Japan.

Crit Care 2022 05 9;26(1):129. Epub 2022 May 9.

Department of Emergency and Critical Care Medicine, Urasoe General Hospital, Okinawa, Japan.

Background: The prevalence of extracorporeal cardiopulmonary resuscitation (ECPR) in patients with out-of-hospital cardiac arrest (OHCA) has been increasing rapidly worldwide. However, guidelines or clinical studies do not provide sufficient data on ECPR practice. The aim of this study was to provide real-world data on ECPR for patients with OHCA, including details of complications. Read More

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Outcomes of cardiopulmonary resuscitation in patients with pulmonary arterial hypertension.

Pulm Circ 2022 Apr 1;12(2):e12066. Epub 2022 Apr 1.

Department of Medicine, Division of Pulmonary, Critical Care, and Sleep Medicine University of California San Diego La Jolla California USA.

Over the past 20 years, despite significant advancements in pulmonary arterial hypertension (PAH) medical therapy, many patients require admission to the hospital and are at risk for in-hospital cardiac arrest (IHCA). Prior data found poor survival in PAH patients after cardiac arrest. The purpose of this study was to explore post-IHCA outcomes in PAH patients receiving advanced medical therapies. Read More

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Cardiac arrest during endotracheal intubation of children with systolic dysfunction.

Cardiol Young 2022 May 4:1-7. Epub 2022 May 4.

Division of Cardiology, Cardiac Intensive Care, Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL, USA.

This multicenter study aimed to describe peri-intubation cardiac arrest in paediatric cardiac patients with significant (moderate or severe) systolic dysfunction of the systemic ventricle. Intubation data were collected from 4 paediatric cardiac ICUs in the United States (January 2015 - December 2017). Clinician practices during intubation of patients with significant dysfunction were compared to practices during intubation of patients without significant systolic dysfunction. Read More

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Pulseless electrical activity in in-hospital cardiac arrest - A crossroad for decisions.

Resuscitation 2022 Apr 28. Epub 2022 Apr 28.

Department of Circulation and Medical Imaging, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology (NTNU), Trondheim, Norway; Department of Anesthesia and Intensive Care Medicine, St Olav University Hospital, Trondheim, Norway.

Background: PEA is often seen during resuscitation, either as the presenting clinical state in cardiac arrest or as a secondary rhythm following transient return of spontaneous circulation (ROSC), ventricular fibrillation/tachycardia (VF/VT), or asystole (ASY). The aim of this study was to explore and quantify the evolution from primary/secondary PEA to ROSC in adults during in-hospital cardiac arrest (IHCA).

Methods: We analyzed 700 IHCA episodes at one Norwegian hospital and three U. Read More

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Fulminant Delta COVID-19 myocarditis: a case report of fatal primary cardiac dysfunction.

Eur Heart J Case Rep 2022 Apr 13;6(4):ytac142. Epub 2022 Apr 13.

Department of Cardiology, Royal Prince Alfred Hospital, Sydney, Australia.

Background: Whilst myocarditis or myocardial injury due to severe acute respiratory syndrome coronavirus 2 infection is commonly reported, profound primary cardiac dysfunction requiring mechanical circulatory support, with the development of fulminant myocarditis prior to respiratory failure, is rarely described. The endomyocardial biopsy (EMB) findings in these patients is seldom reported, the findings are varied, and effective treatment unknown.

Case Summary: A 39-year-old female with no significant past medical history and confirmed Delta variant coronavirus disease 2019 (COVID-19) infection (Day 3), presented with a 1 day history of diarrhoea, vomiting, and abdominal pain. Read More

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Prediction of Sudden Cardiac Death Manifesting With Documented Ventricular Fibrillation or Pulseless Ventricular Tachycardia.

JACC Clin Electrophysiol 2022 Apr 30;8(4):411-423. Epub 2022 Mar 30.

Department of Emergency Medicine, Oregon Health and Science University, Portland, Oregon, USA.

Objectives: This study aimed to develop a novel clinical prediction algorithm for avertable sudden cardiac death.

Background: Sudden cardiac death manifests as ventricular fibrillation (VF)/ ventricular tachycardia (VT) potentially treatable with defibrillation, or nonshockable rhythms (pulseless electrical activity/asystole) with low likelihood of survival. There are no available clinical risk scores for targeted prediction of VF/VT. Read More

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A Fatal Case of Takotsubo Cardiomyopathy Secondary to Refractory Hypoglycemia in Severe Starvation: An Autopsy Case Report.

Cureus 2022 Mar 18;14(3):e23287. Epub 2022 Mar 18.

Advanced Critical Care and Emergency Center, Yokohama City University Medical Center, Yokohama, JPN.

A 56-year-old, severely malnourished man presented with loss of consciousness due to hypoglycemia. Echocardiography revealed left ventricular apical ballooning, indicating takotsubo cardiomyopathy. Although his caloric intake was gradually increased to avoid refeeding syndrome, hypoglycemia was refractory, and repetitive glucose administration was required. Read More

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Survival and neurological outcome after out-of-hospital cardiac arrest treated with and without mechanical circulatory support.

Resusc Plus 2022 Jun 6;10:100230. Epub 2022 Apr 6.

Department of Cardiology, Aarhus University Hospital, Denmark.

Aim: The aim of this study was to describe the survival and neurological outcome in patients with OHCA treated with and without mechanical circulatory support (MCS).

Methods: This was a retrospective observational cohort study on patients with OHCA admitted to Aarhus University Hospital, Denmark, between January 2015 and December 2019. Kaplan-Meier estimates were used to evaluate 30-day and 30-180-day survival. Read More

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Out-of-hospital cardiac arrest with onset witnessed by emergency medical services: Implications for improvement in overall survival.

Resuscitation 2022 Jun 11;175:19-27. Epub 2022 Apr 11.

Center for Cardiac Arrest Prevention, Department of Cardiology, Smidt Heart Institute, Cedars-Sinai Health System, Los Angeles, CA, United States; Division of Artificial Intelligence in Medicine, Department of Medicine, Cedars-Sinai Health System, Los Angeles, CA, United States. Electronic address:

Out-of-hospital cardiac arrest (OHCA) remains a major public health problem. Even in high-income countries, survival rates have plateaued in the range of ten percent, stimulating an ongoing interest in developing novel approaches to resuscitation. Emergency Medical Services (EMS)-witnessed OHCAs constitute a subgroup of overall OHCA that occur after the arrival of EMS, leading to rapid initiation of resuscitation and significantly improved survival. Read More

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Acute myeloid leukemia causing acute thrombosis of the coronary arteries: a case report.

J Med Case Rep 2022 Apr 12;16(1):149. Epub 2022 Apr 12.

Division of Cardiovascular Medicine, Section of Cardiac Electrophysiology at the University of California San Diego Health System, 9452 Medical Center Drive, La Jolla, CA, 92037, USA.

Background: This case report demonstrates acute myeloid leukemia causing acute thrombosis of coronary arteries with anterolateral ST elevation myocardial infarction and ventricular tachycardia in an otherwise healthy woman. Few case reports have been documented on patients with concomitant conditions of acute myeloid leukemia and acute myocardial infarction, and it is important to note that prognosis for patients with both is worse than that of either condition. While both conditions together are rare, other non-atherosclerotic causes of acute coronary syndromes are likewise important considerations in the context of myocardial ischemia. Read More

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The epidemiology and outcomes of adult in-hospital cardiac arrest in a high-income developing country.

Resusc Plus 2022 Jun 19;10:100220. Epub 2022 Mar 19.

Department of Internal Medicine, College of Medicine and Health Sciences, UAE University, Al Ain, United Arab Emirates.

Aim: In-Hospital Cardiac Arrest (IHCA) is a significant burden on healthcare worldwide. Outcomes of IHCA are worse in developing countries compared with developed ones. We aimed to study the epidemiology and factors determining outcomes in adult IHCA in a high income developing country. Read More

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Short-term effects of endotracheal suctioning in post-cardiac arrest patients: A prospective observational cohort study.

Resusc Plus 2022 Jun 19;10:100221. Epub 2022 Mar 19.

Department of Circulation and Medical Imaging, Faculty of Medicine and Heath Sciences, Norwegian University of Science and Technology, No-7491 Trondheim, Norway.

Background: Endotracheal suctioning (ETS) is required in critically ill patients but may lead to adverse physiologic effects. The aim of this study was to investigate risk factors associated with adverse respiratory and circulatory effects of ETS, in post-cardiac arrest patients receiving controlled ventilation.

Methods: Patients with return of spontaneous circulation after out-of-hospital cardiac arrest were followed the first five days in the intensive care unit (ICU). Read More

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The impact of on-site cardiac rhythm on mortality in patients supported with extracorporeal cardiopulmonary resuscitation: A retrospective cohort study.

Artif Organs 2022 Mar 22. Epub 2022 Mar 22.

Department of Anaesthesiology and Pain Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.

Background: Extracorporeal cardiopulmonary resuscitation (ECPR) is increasingly used in patients with out-of-hospital or in-hospital cardiac arrest in whom conventional cardiopulmonary resuscitation remains unsuccessful. The aim of this study was to analyze the impact of initial cardiac rhythm-detected on-site of the cardiac arrest-on mortality.

Methods: We performed a retrospective cohort study of patients who received ECPR in our tertiary care cardiac arrest center. Read More

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Sudden cardiac death in congenital heart disease.

Eur Heart J 2022 Mar 18. Epub 2022 Mar 18.

Hôpital Européen Georges Pompidou, Université de Paris, Paris, France.

Sudden cardiac death (SCD) accounts for up to 25% of deaths in patients with congenital heart disease (CHD). To date, research has largely been driven by observational studies and real-world experience. Drawbacks include varying definitions, incomplete taxonomy that considers SCD as a unitary diagnosis as opposed to a terminal event with diverse causes, inconsistent outcome ascertainment, and limited data granularity. Read More

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Higher chance of survival in patients with out-of-hospital cardiac arrest attributed to poisoning.

Resuscitation 2022 Jun 11;175:96-104. Epub 2022 Mar 11.

Institute for Emergency Medicine, University Hospital Schleswig-Holstein, Arnold-Heller-Straße 3, Building 404, 24105 Kiel, Germany; Department of Anaesthesiology and Intensive Care Medicine, University Hospital Schleswig-Holstein, Campus Kiel, Arnold-Heller-Straße 3, Building R3, 24105 Kiel, Germany. Electronic address:

Aim Of The Study: Description and comparison of cohort characteristics and outcome of adult patients with out-of-hospital cardiac arrest (OHCA) attributed to poisoning (P-OHCA) versus patients with OHCA attributed to other medical causes (NP-OHCA).

Methods: We included all patients who received cardiopulmonary resuscitation after OHCA between January 2011 and December 2020 from German emergency medical services with good data quality in the German Resuscitation Registry.

Exclusion Criteria: patients < 18 years of age or OHCA attributed to trauma, drowning, intracranial bleeding or exsanguination. Read More

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Etiologies of In-hospital cardiac arrest: A systematic review and meta-analysis.

Resuscitation 2022 Jun 10;175:88-95. Epub 2022 Mar 10.

University of Texas at Austin- Dell Medical School, Austin, TX, USA.

Background: Etiologies of in-hospital cardiac arrest (IHCA) in general wards may differ from etiologies of out-of-hospital cardiac arrest (OHCA) given the different clinical characteristics of these patient populations. An appreciation for the causes of IHCA may allow the clinician to appropriately target root causes of arrest.

Methods: MEDLINE/PubMed, EMBASE, and Google Scholar were queried from inception until May 31, 2021. Read More

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Postoperative vasovagal cardiac arrest after spinal anesthesia for lumbar spine surgery.

Surg Neurol Int 2022 11;13:42. Epub 2022 Feb 11.

Department of Neurosurgery, Tufts Medical Center, Washington, Boston, United States.

Background: Spinal anesthesia is being increasingly recognized as a favorable alternative to general anesthesia. However, there are still several considerations for its safe and effective use.

Case Description: A 62-year-old male received spinal anesthesia during an uneventful L3-L5 decompressive laminectomy. Read More

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February 2022

Delayed administration of epinephrine is associated with worse neurological outcomes in patients with out-of-hospital cardiac arrest and initial pulseless electrical activity: insight from the nationwide multicentre observational JAAM-OHCA (Japan Association for Acute Medicine) registry.

Eur Heart J Acute Cardiovasc Care 2022 Mar 3. Epub 2022 Mar 3.

Department of Cardiovascular Medicine, Faculty of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan.

Aims: The delayed administration of epinephrine has been proven to worsen the neurological outcomes of patients with out-of-hospital cardiac arrest (OHCA) and shockable rhythm or asystole. We aimed to investigate whether the delayed administration of epinephrine might also worsen the neurological outcomes of patients with witnessed OHCA and initial pulseless electrical activity (PEA).

Methods And Results: The JAAM-OHCA Registry is a multicentre registry including OHCA patients between 2014 and 2017. Read More

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Virtual Reality Simulation Training for Cardiopulmonary Resuscitation After Cardiac Surgery: Face and Content Validity Study.

JMIR Serious Games 2022 Mar 2;10(1):e30456. Epub 2022 Mar 2.

Department of Cardiothoracic Surgery, Erasmus University Medical Center, Rotterdam, Netherlands.

Background: Cardiac arrest after cardiac surgery commonly has a reversible cause, where emergency resternotomy is often required for treatment, as recommended by international guidelines. We have developed a virtual reality (VR) simulation for training of cardiopulmonary resuscitation (CPR) and emergency resternotomy procedures after cardiac surgery, the Cardiopulmonary Resuscitation Virtual Reality Simulator (CPVR-sim). Two fictive clinical scenarios were used: one case of pulseless electrical activity (PEA) and a combined case of PEA and ventricular fibrillation. Read More

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Pulseless electrical activity and asystolic cardiac arrest in infants: identifying factors that influence outcomes.

J Perinatol 2022 May 17;42(5):574-579. Epub 2022 Feb 17.

UT Southwestern Medical Center Department of Pediatrics Division of Neonatal-Perinatal Medicine, Dallas, TX, USA.

Background: There is limited information on pulseless electrical activity (PEA)/asystolic cardiac arrest (CA) in the infant population. The aim is to describe the incidence and factors associated with outcomes in infants with PEA/asystolic CA.

Methods: Single-center retrospective chart review study of infants less than one year of age who suffer in-hospital PEA/asystolic CA from January 1 2011 to June 30 2019. Read More

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Assessment of emergency physicians' performance in identifying shockable rhythm in out-of-hospital cardiac arrest: an observational simulation study.

Emerg Med J 2022 May 16;39(5):347-352. Epub 2022 Feb 16.

Paris Fire Brigade, Paris, France.

Background: Emergency physicians can use a manual or an automated defibrillator to provide defibrillation of patients who had out-of-hospital cardiac arrest (OHCA). Performance of emergency physicians in identifying shockable rhythm with a manual defibrillator has been poorly explored whereas that of automated defibrillators is well known (sensitivity 0.91-1. Read More

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Epidemiology and Outcome of Pediatric Out-of-Hospital Cardiac Arrest after Traffic Collision in Japan: A Population-Based Study.

J Clin Med 2022 Feb 4;11(3). Epub 2022 Feb 4.

Department of Traumatology and Acute Critical Medicine, Graduate School of Medicine, Osaka University, 2-15, Yamada-oka, Suita 565-0871, Japan.

The epidemiological and clinical characteristics, treatments, and outcomes of patients with traumatic out-of-hospital cardiac arrests (OHCAs) following traffic collisions have not been adequately investigated in Japan. We analyzed the All-Japan Utstein Registry data of 918 pediatric patients aged <20 years with OHCAs following traffic collisions who were resuscitated by bystanders or emergency medical service personnel and were subsequently transported to hospitals between 2013 and 2019. Multiple logistic regression analysis was used to assess factors potentially associated with 1-month survival after OHCA. Read More

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February 2022

Survival Trends in Adults with Out-of-Hospital Cardiac Arrests after Traffic Collisions in Japan: A Population-Based Study.

J Clin Med 2022 Jan 29;11(3). Epub 2022 Jan 29.

Department of Traumatology and Acute Critical Medicine, Graduate School of Medicine, Osaka University, 2-15 Yamadaoka, Suita 565-0871, Japan.

The 1-month survival rate from out-of-hospital cardiac arrest (OHCA) of cardiac origin has reportedly improved recently, at ≥5%. However, the characteristics of patients with OHCA after a traffic collision have not been adequately evaluated in Japan. We analyzed the All-Japan Utstein Registry data of 12,577 adult patients aged ≥ 20 years with OHCA due to traffic collisions who were resuscitated by emergency medical service personnel or bystanders and were then transported to medical institutions between 2013 and 2019. Read More

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January 2022

Lacosamide-Related Arrhythmias: A Systematic Analysis and Review of the Literature.

Cureus 2021 Dec 27;13(12):e20736. Epub 2021 Dec 27.

Interventional Cardiology, Marshfield Clinic Medical Center, Eau Claire, USA.

Lacosamide (LCM) is a new antiepileptic drug used as an adjunctive treatment for partial seizures with and without secondary generalization. One of the modes of action is the enhancement of slow inactivation of voltage-gated sodium channels. Experimental studies and clinical trials suggest that LCM acts upon both neurons and the heart and may increase the risk of cardiac arrhythmias. Read More

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December 2021

Cardiac Arrhythmias and COVID-19: Correlation With Disease Severity.

Cureus 2021 Dec 18;13(12):e20507. Epub 2021 Dec 18.

Cardiovascular Disease, Mount Sinai Hospital, New York City, USA.

Background Cardiac arrhythmia is one of the life-threatening cardiovascular complications commonly reported in patients hospitalized with coronavirus disease 2019 (COVID-19). We aimed to evaluate the association between cardiac arrhythmias and disease severity based on oxygen requirement. Methods In this retrospective observational chart review-based study we recruited 396 patients hospitalized with COVID-19 from March 2020 to May 2020 from two regional medical centers in New Jersey, USA. Read More

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December 2021

Kounis syndrome caused by protamine shock after coronary intervention: A case report.

J Cardiol Cases 2022 Jan 3;25(1):23-25. Epub 2021 Jul 3.

Division of Cardio-angiology and Nephrology, Department of Internal Medicine, Iwate Medical University, Yahaba, Japan.

We report a case of Kounis syndrome that led to shock after protamine administration during percutaneous coronary intervention (PCI). A man in his 50s was admitted to the nearest hospital following the onset of acute myocardial infarction. Coronary angiography showed a single-vessel lesion in the left anterior descending artery (LAD). Read More

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January 2022

Cardiac Arrest during Transesophageal Echocardiogram (TEE) due to Acute Right Ventricular Failure.

Case Rep Cardiol 2021 24;2021:7427127. Epub 2021 Dec 24.

University of Washington, Division of Cardiology, USA.

The case of a patient who suffered cardiac arrest while undergoing transesophageal echocardiography (TEE) is presented here. A 75-year-old man with moderate right ventricular (RV) dysfunction and pulmonary hypertension became bradycardic and hypotensive after receiving propofol for procedural sedation. His profound hypotension ultimately led to a pulseless electrical activity (PEA) cardiac arrest. Read More

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December 2021

Paramedic rhythm interpretation misclassification is associated with poor survival from out-of-hospital cardiac arrest.

Resuscitation 2022 02 21;171:33-40. Epub 2021 Dec 21.

Division of Emergency Medicine, University of Utah School of Medicine, Salt Lake City, Utah, United States; Salt Lake City Fire Department, Salt Lake City, Utah, United States.

Background: Early recognition and rapid defibrillation of shockable rhythms is strongly associated with survival in out of hospital cardiac arrest (OHCA). Little is known about the accuracy of paramedic rhythm interpretation and its impact on survival. We hypothesized that inaccurate paramedic interpretation of initial rhythm would be associated with worse survival. Read More

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February 2022

Outcomes and interventions in patients transported to hospital with ongoing CPR after out-of-hospital cardiac arrest - An observational study.

Resusc Plus 2021 Dec 16;8:100170. Epub 2021 Oct 16.

Center for Cardiac Arrest, Department of Clinical Sciences Lund, Lund University, Lund, Sweden.

Introduction: The main objective was to present characteristics and outcome of patients without sustained field return of spontaneous circulation (ROSC) transported to hospital with ongoing cardiopulmonary resuscitation (CPR). Our secondary objectives were to investigate hospital-based interventions and the performance of the universal Termination of Resuscitation-rule (uTOR).

Methods: In this retrospective observational cohort study, out-of-hospital cardiac arrest (OHCA) patients arriving to the emergency department of a university hospital in Sweden during a six-year period (2010-2015) were identified using a prospectively recorded hospital-based registry. Read More

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December 2021