14,640 results match your criteria Pulmonic Valvular Stenosis


Conversion of Norwood-Rastelli Procedure to "Anatomic" Biventricular Circulation With Takedown of Aortopulmonary Amalgamation After Aortic Valve Growth.

World J Pediatr Congenit Heart Surg 2022 Jul;13(4):503-507

Department of Cardiovascular Surgery, 38088Kitasato University School of Medicine, Kanagawa, Japan.

The pathways for biventricular repair of hypoplastic aortic arch with ventricular septal defect, small aortic valve, and normal-sized left ventricle vary depending on the disease spectrum. We report a case of an infant who underwent a staged Norwood-Rastelli procedure for aortic stenosis (bicuspid aortic valve), hypoplastic aortic arch, and coarctation of the aorta with ventricular septal defect and normal-sized left ventricle. Ten years after the initial surgery, normal circulatory physiology was achieved with a takedown of the aortopulmonary amalgamation and VSD closure. Read More

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Long-Term Results after Fallot Repair.

Thorac Cardiovasc Surg 2022 Dec 25;70(S 03):e7-e14. Epub 2022 Jun 25.

Universitäts-Kinderspital Zürich, Zurich, Switzerland.

Background:  The aim of this study was to evaluate the long-term outcome and freedom from pulmonary valve replacement (PVR) after initial repair of tetralogy of Fallot (TOF).

Patients And Methods:  The cohort of 306 patients treated between 1980 and 2017 was divided into anatomical subgroups according to the diagnosis of TOF-pulmonary stenosis, TOF-pulmonary atresia and TOF-double outlet right ventricle. Patients were treated with transannular patch (TAP), valve sparing repair (VSR), or conduits from the right ventricle to the pulmonary arteries (RVPA conduits). Read More

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December 2022

Real-life outcomes and readmissions after a TAVI procedure in a Glasgow population.

Br J Cardiol 2021 1;28(3):37. Epub 2021 Sep 1.

Consultant Cardiologist Department of Cardiology, Queen Elizabeth University Hospital, 1345 Govan Road, Glasgow, G51 4TF.

Transcatheter aortic valve implantation (TAVI) is a routine procedure for patients with symptomatic severe aortic stenosis who are deemed inoperable or high-risk surgical candidates. The aim of this study was to examine real-world data on death and readmission rates in patients following the procedure. Electronic health records for patients who underwent TAVI between April 2015 and November 2018 were reviewed. Read More

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September 2021

Models and Techniques to Study Aortic Valve Calcification , and . An Overview.

Front Pharmacol 2022 2;13:835825. Epub 2022 Jun 2.

Department of Molecular Medicine, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.

Aortic valve stenosis secondary to aortic valve calcification is the most common valve disease in the Western world. Calcification is a result of pathological proliferation and osteogenic differentiation of resident valve interstitial cells. To develop non-surgical treatments, the molecular and cellular mechanisms of pathological calcification must be revealed. Read More

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Anesthetic management for cesarean section in parturient with an uncorrected single ventricle: A case report and literature review.

Medicine (Baltimore) 2022 Jun 17;101(24):e29421. Epub 2022 Jun 17.

Department of Anesthesiology, Affiliated Hospital of North Sichuan Medical College, Nanchong, China.

Rationale: Patients with a single ventricle, who have not undergone surgery, reportedly have a lower survival rate. Furthermore, multiple pregnancies are rare among these females. We reported a case of anesthesia management of cesarean section in an uncorrected single-ventricular multi-pregnancy woman and review the anesthesia management of the published similar cases. Read More

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Treatment of secondary mitral regurgitation by transcatheter edge-to-edge repair using MitraClip.

J Med Ultrason (2001) 2022 Jun 16. Epub 2022 Jun 16.

Department of Cardiology, Dokkyo Medical University Saitama Medical Center, Minamikoshigaya 2-1-50, Koshigaya, Saitama, 343-8555, Japan.

Transcatheter edge-to-edge repair (TEER) is becoming the standard invasive treatment for ventricular functional mitral regurgitation (MR). It is necessary to determine the severity of MR before treatment with MitraClip; however, the severity of secondary MR is usually underestimated compared with that of primary MR and varies temporally. Therefore, to accurately determine the severity of MR, it is important to correctly use the algorithm of the guidelines for valvular heart disease and aggressively perform stress echocardiography. Read More

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Does the "obesity paradox" exist after transcatheter aortic valve implantation?

J Cardiothorac Surg 2022 Jun 13;17(1):156. Epub 2022 Jun 13.

Key Laboratory of Cardio-Thoracic Surgery, Department of Cardiovascular Surgery and Cardiac Disease Center, Union Hospital, Fujian Medical University, Fujian Province University, Fuzhou, 350001, People's Republic of China.

Background: Transcatheter aortic valve implantation (TAVI) for symptomatic aortic stenosis is considered a minimally invasive procedure. Body mass index (BMI) has been rarely evaluated for pulmonary complications after TAVI. This study aimed to assess the influence of BMI on pulmonary complications and other related outcomes after TAVI. Read More

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Venoarterial Extracorporeal Membrane Oxygenation to Facilitate Transcutaneous Mitral Valve Replacement in Critical Mitral Stenosis.

JACC Case Rep 2022 Apr 6;4(7):385-390. Epub 2022 Apr 6.

Division of Cardiology, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York, USA.

Biological mitral valve restenosis after replacement in rheumatic heart disease is a rare complication. This case illustrates venoarterial extracorporeal membrane oxygenation to facilitate transcatheter mitral valve replacement in a patient with suprasystemic pulmonary pressure and cardiogenic shock with multiorgan failure secondary to critical mitral stenosis of a bioprosthetic valve.(). Read More

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Comparison of PCWP and LVEDP Measurements in Patients with Severe Aortic Stenosis Undergoing TAVI-Same Same but Different?

J Clin Med 2022 May 25;11(11). Epub 2022 May 25.

Department of Internal Medicine II, Division of Cardiology, Paracelsus Medical University of Salzburg, 5020 Salzburg, Austria.

Background: Pulmonary capillary wedge pressure (PCWP) and left ventricular end-diastolic pressure (LVEDP) are often used as equivalents for determination of pulmonary hypertension (PH). PH is a comorbidity in patients with severe aortic valve stenosis (AS) and associated with limited prognosis. The aim of the study was to examine the role of differentiated classification basis of PCWP and LVEDP in patients planning for transcatheter aortic valve implantation (TAVI). Read More

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Severe Rheumatic Mitral Stenosis, Worse Left Atrial Mechanics is Closely Associated with Echo Criteria for Intervention.

J Cardiovasc Echogr 2022 Jan-Mar;32(1):38-46. Epub 2022 Apr 20.

University of Glasgow, Adult Congenital Cardiac Service, Glasgow, Scotland.

Background: Rheumatic mitral valve (MV) stenosis is associated with progressive left atrial (LA) fibrosis and functional impairment, Pulmonary artery systolic pressure (PASP) and right ventricular (RV) dysfunction. The aims of the study were to determine in those patients with severe MV stenosis if LA mechanical function as assessed by speckle tracking echocardiography could identify those with increased PASP, atrial fibrillation (AFib), and RV dysfunction.

Subjects And Methods: Patients with severe MV stenosis were identified from the institutional echo database. Read More

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Prevalence of Genetic Diagnoses in a Cohort With Valvar Pulmonary Stenosis.

Circ Genom Precis Med 2022 Jun 6:101161CIRCGEN121003635. Epub 2022 Jun 6.

Heart Institute, Cincinnati Children's Hospital Medical Center. (K.N.W., A.S., J.F.C.).

Background: Valvar pulmonary stenosis (vPS) accounts for 8% to 12% of congenital heart disease cases. Multiple genetic syndromes are associated with vPS, most commonly Noonan syndrome, but the cause is unknown in most cases. We analyzed genomic data from a large cohort with vPS to determine the prevalence of genetic diagnosis. Read More

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Prevalence and Natural History of Mitral Annulus Calcification and Related Valve Dysfunction.

Mayo Clin Proc 2022 Jun;97(6):1094-1107

Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN. Electronic address:

Objective: To evaluate the prevalence and natural history of mitral annulus calcification (MAC) and associated mitral valve dysfunction (MVD) in patients undergoing clinically indicated echocardiography.

Methods: A retrospective review was conducted of all adults who underwent echocardiography in 2015. Mitral valve dysfunction was defined as mitral regurgitation or mitral stenosis (MS) of moderate or greater severity. Read More

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Prognostic value of systemic inflammatory response syndrome after transcatheter aortic valve implantation.

J Cardiovasc Med (Hagerstown) 2022 Jun;23(6):394-398

Department of Clinical, Internal, Anaesthesiology and Cardiovascular Sciences, 'Sapienza' University of Rome, Policlinico Umberto I, Rome, Italy.

Aims: Systemic inflammatory response syndrome (SIRS) could affect mortality after transcatheter aortic valve implantation (TAVI) up to 12 months of follow-up. The aim of this study was to evaluate the prevalence of SIRS after TAVI and its impact on all-cause mortality up to 24 months follow-up.

Methods: We retrospectively enrolled 132 patients with symptomatic severe aortic stenosis undergoing TAVI. Read More

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Multiparametric MRI identifies subtle adaptations for demarcation of disease transition in murine aortic valve stenosis.

Basic Res Cardiol 2022 05 29;117(1):29. Epub 2022 May 29.

Cardiovascular Research Laboratory, Division of Cardiology, Pulmonary Diseases and Vascular Medicine, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany.

Aortic valve stenosis (AS) is the most frequent valve disease with relevant prognostic impact. Experimental model systems for AS are scarce and comprehensive imaging techniques to simultaneously quantify function and morphology in disease progression are lacking. Therefore, we refined an acute murine AS model to closely mimic human disease characteristics and developed a high-resolution magnetic resonance imaging (MRI) approach for simultaneous in-depth analysis of valvular, myocardial as well as aortic morphology/pathophysiology to identify early changes in tissue texture and critical transition points in the adaptive process to AS. Read More

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Artificial intelligence-based stethoscope for the diagnosis of aortic stenosis.

Am J Med 2022 May 28. Epub 2022 May 28.

Department of Cardiology, Lady Davis Carmel Medical Center, Haifa, Israel; the Ruth and Bruce Rappaport Faculty of Medicine, Technion, Israel Institute of Technology, Haifa, Israel. Electronic address:

Background: The diagnostic accuracy of the stethoscope is limited and highly dependent on clinical expertise. Our purpose was to develop an electronic stethoscope, based on artificial intelligence (AI) and infrasound, for the diagnosis of aortic stenosis (AS).

Methods: We used an electronic stethoscope (Voqx, Sanolla) with subsonic capabilities and acoustic range of 3-2,000 Hz. Read More

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Acute Rheumatic Fever and Rheumatic Heart Disease: Highlighting the Role of Group A Streptococcus in the Global Burden of Cardiovascular Disease.

Pathogens 2022 Apr 21;11(5). Epub 2022 Apr 21.

Faculty of Medicine, Universidade Eduardo Mondlane, Maputo 1113, Mozambique.

Group A Streptococcus (GAS) causes superficial and invasive infections and immune mediated post-infectious sequalae (including acute rheumatic fever/rheumatic heart disease). Acute rheumatic fever (ARF) and rheumatic heart disease (RHD) are important determinants of global cardiovascular morbidity and mortality. ARF is a multiorgan inflammatory disease that is triggered by GAS infection that activates the innate immune system. Read More

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Clinical Impact of Heart Team Decisions for Patients With Complex Valvular Heart Disease: A Large, Single-Center Experience.

J Am Heart Assoc 2022 Jun 27;11(11):e024404. Epub 2022 May 27.

Fondazione Policlinico Universitario A. Gemelli IRCCS Roma Italia.

Background A multidisciplinary approach might be pivotal for the management of patients with valvular heart disease (VHD), but clinical outcome data are lacking. Methods and Results At our institution, since 2014, internal guidelines recommended heart team consultations for patients with VHD. The clinical/echocardiographic characteristics, treatment recommendations, performed treatment, and early clinical outcomes of consecutive, hospitalized patients with VHD undergoing heart team evaluation were collected. Read More

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Retrograde Pulmonary Vein Recanalization Using Transcatheter Electrosurgery.

JACC Case Rep 2022 May 18;4(10):592-595. Epub 2022 May 18.

Division of Cardiology, Children's Healthcare of Atlanta, Atlanta, Georgia, USA.

Transcatheter electrosurgery is a wire-based technique used to traverse or cut tissue within blood-filled spaces using alternating current delivered by guidewires or catheters. The use of transcatheter electrosurgical techniques in the pediatric population has been limited. We are reporting the first case of retrograde pulmonary vein recanalization using transcatheter electrosurgery. Read More

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An Extremely Rare Case of Bonneau Syndrome with Novel Cardiac and Eye Manifestations.

Saudi J Med Med Sci 2022 May-Aug;10(2):166-169. Epub 2022 Apr 28.

Department of Pediatrics, Thumbay University Hospital, Ajman, UAE.

Bonneau or cardio-ducto-polysyndactyly syndrome is an extremely rare, life-threatening developmental defect, which has only been reported in eight patients previously. Here, we describe one such case of Bonneau syndrome in a newborn with additional novel manifestations. This late preterm (35 weeks of gestation) neonate born to parents of consanguineous marriage following a pregnancy complicated by polyhydramnios was symmetrically small for date at birth (<3 centile for weight, length, and occipitofrontal circumference). Read More

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Takayasu arteritis with congestive heart failure in 26-year-old male: a case report.

Egypt Heart J 2022 May 21;74(1):41. Epub 2022 May 21.

Faculty of Medicine, University of Jember, Jl. Kalimantan No. 37, Jember, East Java, 68121, Indonesia.

Background: Takayasu arteritis (TA) is included in large vessel vasculitis with unknown aetiopathogenesis. TA is one of the rare diseases with a predilection for young women. The diagnosis of TA is difficult due to variation in clinical presentations and non-specific initial symptoms. Read More

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Evolution and Prognostic Impact of Cardiac Damage After Aortic Valve Replacement.

J Am Coll Cardiol 2022 May 14. Epub 2022 May 14.

Clinical Trials Center, Cardiovascular Research Foundation, New York, New York; St. Francis Hospital and Heart Center, Roslyn, New York.

Background: The impact of aortic valve replacement (AVR) on progression/regression of extra-valvular cardiac damage and its association with subsequent prognosis is unknown.

Objectives: To describe evolution of cardiac damage post-AVR and its association with outcomes.

Methods: Patients undergoing transcatheter or surgical AVR from the PARTNER 2 and 3 trials were pooled and classified by cardiac damage stage at baseline and 1-year (Stage 0, no damage; Stage 1, left ventricular damage; Stage 2, left atrial or mitral valve damage; Stage 3, pulmonary vasculature or tricuspid valve damage; Stage 4, right ventricular damage). Read More

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Transcatheter aortic valve implantation with a balloon-expandable prosthesis in a patient with single coronary artery: a case report.

Eur Heart J Case Rep 2022 May 3;6(5):ytac192. Epub 2022 May 3.

Division of Cardiovascular Surgery, Hokkaido Cardiovascular Hospital, 1-30 South27 West13, Chuo-ku, Sapporo City 064-8622, Japan.

Background: Single coronary artery is a rare coronary artery anomaly with an incidence of <0.03%. The coexistence of coronary artery anomalies with severe aortic stenosis is extremely rare. Read More

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Atresia of the Midportion of the Coronary Sinus: A Case Report.

World J Pediatr Congenit Heart Surg 2022 May 18:21501351221099940. Epub 2022 May 18.

20567Congenital Heart Center Nevada, Las Vegas, NV, USA.

A 12-year-old with a history of critical pulmonary stenosis and moderate right ventricular hypoplasia underwent neonatal pulmonary valve dilation, an aortopulmonary shunt, and an infant cavopulmonary anastomosis with aortopulmonary shunt takedown. During a diagnostic cardiac catheterization at 12 years of age, angiography showed interruption in the midportion of the coronary sinus, which required no intervention. Read More

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Non-surgical treatment of Lutembacher syndrome: combined percutaneous transcatheter therapy.

BMJ Case Rep 2022 May 18;15(5). Epub 2022 May 18.

Periodontology, AB Shetty Memorial Institute of Dental Sciences, Mangalore, Karnataka, India.

A woman in her 30s presented with progressive worsening of dyspnoea for 6 months. On evaluation, she was diagnosed with severe rheumatic mitral stenosis (mitral valve area of 0.6 cm) and a large ostium secundum atrial septal defect (21 mm) with a left to right shunt and severe pulmonary artery hypertension. Read More

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Tetralogy of Fallot in the fetus - from diagnosis to delivery. 18-year experience of a tertiary Fetal Cardiology Center.

Kardiol Pol 2022 May 17. Epub 2022 May 17.

Department of Perinatal Cardiology and Congenital Anomalies, Center of Postgraduate Medical Education, Warszawa, Poland.

Background: Tetralogy of Fallot (TOF) is a common congenital heart disease, however very heterogenous in terms of detailed cardiac anatomy, associated malformations and genetic anomalies, especially when assessed prenatally.

Aims: Our aim was to analyze the clinical spectrum of TOF in the prenatal period, including detailed cardiac morphology, coexisting anomalies, and their impact on short-term neonatal outcome. We also assessed changing trends in the prenatal diagnostic workup of TOF. Read More

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Pulmonary artery systolic pressure at 1-month predicts one-year survival after transcatheter aortic valve implantation.

Kardiol Pol 2022 May 16. Epub 2022 May 16.

Department of Cardiac Surgery and Transplantology, Poznan University of Medical Sciences, Poznań, Poland.

Background: Pulmonary hypertension related to left ventricle heart disease is a common finding in patients with severe aortic stenosis treated with transcatheter aortic valve implantation (TAVI) and is associated with higher mortality rate.

Aims: The aim of the study was to analyze the influence of pulmonary artery systolic pressure (PASP) changes after TAVI on long-term survival.

Methods: TAVI was performed in 362 patients between January 2013 and December 2018. Read More

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An Unusual Cause of Shortness of Breath: Pulmonary Vein Stenosis After Surgical Mitral Valve Replacement.

JACC Case Rep 2022 May 4;4(9):533-537. Epub 2022 May 4.

Division of Cardiology, Columbia University Irving Medical Center, New York, New York, USA.

A 79-year-old man with prior bioprosthetic mitral valve replacement presented with progressive shortness of breath and was found to have right upper pulmonary vein stenosis and paravalvular leak diagnosed with the use of multimodal imaging. The patient underwent balloon angioplasty, stenting of the pulmonary vein, and paravalvular leak closure with ultimate resolution of symptoms. (). Read More

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Observational data from the adalimumab post-marketing PYRAMID registry of patients with Crohn's disease who became pregnant: A post hoc analysis.

United European Gastroenterol J 2022 Jun 13;10(5):485-495. Epub 2022 May 13.

Nuffield Department of Medicine, Translational Gastroenterology Unit, Experimental Medicine Division, University of Oxford, John Radcliffe Hospital, Oxford, UK.

Background: PYRAMID was an international post-marketing registry that aimed to collect data on the long-term safety and effectiveness of adalimumab treatment per local standard of care in patients with moderately to severely active Crohn's disease (CD). Here, we present post hoc analyses of observational data from patients who became pregnant while participating in this registry and receiving adalimumab.

Methods: From the subpopulation of patients receiving adalimumab who became pregnant while taking part in PYRAMID, data on patient characteristics, pregnancy outcomes, and complications of pregnancy were analysed retrospectively. Read More

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Transcatheter Aortic Valve Replacement for Mixed Aortic Valve Disease: A Propensity Score-Adjusted Analysis From the RISPEVA Registry.

J Invasive Cardiol 2022 Jun 6;34(6):E419-E427. Epub 2022 May 6.

Azienda Ospedaliero Universitaria Consorziale Policlinico di Bari Piazza G. Cesare 11, Bari, Italy.

Background: The differential outcomes between pure/predominant aortic stenosis (AS) and mixed aortic valve disease (MAVD) in patients undergoing transcatheter aortic valve implantation (TAVI) are still debated.

Objective: To evaluate the comparative clinical outcomes of patients with MAVD and AS undergoing TAVI using data from the RISPEVA registry.

Methods: A total of 3263 patients were included. Read More

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