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Prenat Diagn 2021 Jun 12. Epub 2021 Jun 12.

Fetal & Neonatal Cardiology Program, Division of Pediatric Cardiology, Department of Pediatrics, University of Alberta, Edmonton, Alberta, Canada.

Objectives: To document the clinical spectrum and outcomes of fetal DORV without heterotaxy in a recent diagnostic era.

Methods: Prenatal cases of DORV consecutively diagnosed from 2007-2018 were retrospectively identified. Clinical records, including details regarding genetic testing and pre and postnatal imaging were reviewed. Read More

Int J Cardiovasc Imaging 2021 Jun 9. Epub 2021 Jun 9.

Cardiology Department, Mehmet Akif Ersoy Thoracic And Cardiovascular Surgery Training and Research Hospital, University Of Health Sciences Istanbul, Turgut Ozal Bulvarı no:11, 34303, Istanbul, Küçükçekmece, Turkey.

Mitral stenosis (MS) is tolerated for an extended period in patients with atrial septal defect (ASD) known as Lutembacher syndrome due to depressurizing effect. In a similar way, patients with patent foramen ovale (PFO) may have clinical benefits in severe MS. We aim to evaluate the clinical effects of PFO in rheumatic MS. Read More

J Vet Intern Med 2021 Jun 8. Epub 2021 Jun 8.

Department of Veterinary Medicine and Surgery, Veterinary Health Center, University of Missouri, Columbia, Missouri, USA.

Two juvenile alpacas, 1 male and 1 female, were presented for evaluation of grade V/VI bilateral basilar systolic heart murmurs. Both animals were ultimately diagnosed with severe valvular pulmonic stenosis and a small ventricular septal defect. Transvenous balloon valvuloplasty was performed in each animal using methods described in the dog. Read More

Cardiol Young 2021 Jun 7:1-3. Epub 2021 Jun 7.

Department of Pediatric Cardiology, Max Superspeciality Hospital, Saket, New Delhi, India.

Pulmonary valve endocarditis after transcatheter pulmonary valve implantation has been an emerging concern due to the increasing prevalence of transcatheter placement of pulmonary valve in the treatment of residual right ventricular outflow tract stenosis or regurgitation. Pulmonary valve endocarditis is a dreadful complication of transcatheter pulmonary valve implantation that have been reported with Melody valve (Medtronic, Inc., Minneapolis, MN) and Edward Sapien valve (Edwards Life Sciences, Irvine, CA) till date. Read More

Heart Vessels 2021 Jun 5. Epub 2021 Jun 5.

Department of Pediatric Cardiology, Osaka City General Hospital, Osaka, Japan.

Absent pulmonary valve (APV) syndrome with tricuspid atresia or tricuspid stenosis (TA/TS) is an extremely rare malformation recently reported as a variant of APV with intact ventricular septum (VS). The condition, however, has univentricular physiology and unique structural and clinical features. The purpose of this study was to update the current knowledge about this condition by describing long-term outcomes of three new cases and reviewing the available literatures. Read More

Eur Heart J Qual Care Clin Outcomes 2021 Jun 4. Epub 2021 Jun 4.

Department of Cardiology, Inselspital, University of Bern, Bern, Switzerland.

Aims: A new staging classification of aortic stenosis (AS) characterizing the extent of cardiac damage was established and validated in patients undergoing transcatheter aortic valve implantation (TAVI). We aimed to validate an updated classification system in patients undergoing TAVI.

Methods And Results: In a prospective TAVI registry, AS patients were categorized into the following stages: no cardiac damage (Stage 0), left ventricular damage (Stage 1), left atrial or mitral valve damage (Stage 2), pulmonary vasculature or tricuspid valve damage (Stage 3), or right ventricular (RV) damage or low-flow state (Stage 4). Read More

J Card Surg 2021 May 30. Epub 2021 May 30.

Department of Pediatric Cardiovascular Surgery, Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital, Istanbul, Turkey.

Objective: To describe our short- and medium-term outcomes using the BioIntegral pulmonic conduit.

Methods: Between August 2018 and September 2019, the BioIntegral pulmonic valved conduit was used for right ventricular outflow tract reconstruction in 48 patients. The data were retrospectively retrieved from the patient charts. Read More

Rom J Anaesth Intensive Care 2020 Jul 10;27(1):11-14. Epub 2020 Aug 10.

Department of Anesthesiology, Perioperative Medicine and Pain Treatment, Shaare Zedek Medical Center, affiliated with Hebrew University, Jerusalem, Israel.

Objective: Maternal heart disease is one of the major causes for mortality among parturients. In our study, we surveyed 220 patients with different valvular disorders who gave birth in our medical center in the years 2012-2018. The aim of this study was to characterize various valvular pathologies and compare the results of different anesthetic approaches. Read More

Int Heart J 2021 ;62(3):710-714

Department of Pediatrics and Pediatric Cardiology, Kitasato University.

We present the case of a 1-year-old boy who developed protein-losing enteropathy (PLE) within 2 months of a fenestrated Fontan procedure. His fenestration rapidly closed despite bilateral pulmonary stenosis (BPS). Subsequent to PLE onset, both fenestration and the bilateral pulmonary artery were reconstructed, and the patient's PLE had been in remission, with additive use of medications, for more than 2 years. Read More

Braz J Cardiovasc Surg 2021 Apr 1;36(2):265-267. Epub 2021 Apr 1.

Yancheng Third People's Hospital, Yancheng, China.

Coronary artery to left atrial fistula is rare in patients with mitral stenosis. We report an interesting case of a patient with concomitant mitral valve stenosis and coronary fistulae, originating from the left circumflex artery and drained into the left atrium with two terminal orifices. Read More

J Surg Case Rep 2021 May 17;2021(5):rjab170. Epub 2021 May 17.

Department of Cardiac Surgery, Asahikawa Medical University, Asahikawa, Japan.

Pulmonary valve stenosis and regurgitation can occur in the distant stages after intracardiac repair of tetralogy of Fallot (TOF). Aortic regurgitation (AR) can also occur, although it is rare in postoperative patients. However, there are few reports of simultaneous replacement of the pulmonary and aortic valves in young patients after intracardiac repair of TOF, and there are no clear guidelines for selecting a valve prosthesis in such patients. Read More

JACC Cardiovasc Imaging 2021 May 12. Epub 2021 May 12.

Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands. Electronic address:

Objectives: This study aimed to evaluate the prevalence and prognostic value of the extent of extra-aortic valvular cardiac abnormalities in a large multicenter registry of patients with moderate AS.

Background: The prognostic significance of a new classification system that incorporates the extent of cardiac injury (beyond the aortic valve) has been proposed in patients with severe aortic stenosis (AS). Whether this can be applied to patients with moderate AS is unclear. Read More

J Vet Cardiol 2021 Apr 24;36:1-5. Epub 2021 Apr 24.

Department of Clinical Sciences, Carlson College of Veterinary Medicine, Oregon State University, Corvallis, OR 97331, USA.

A two-year-old, male castrated, French bulldog was presented for evaluation of coronary artery anatomy before balloon valvuloplasty for severe pulmonic valve stenosis. Multidetector computed tomography angiography showed a single left coronary ostium, absent right coronary ostium, and an anomalous, prepulmonic coursing right coronary artery. Medical management was elected to avoid the attendant risk associated with intervention. Read More

Eur Heart J Case Rep 2021 May 12;5(5):ytab097. Epub 2021 May 12.

Schuechtermann-Clinic, Department of Cardiology, Heart-Center Osnabrueck-Bad Rothenfelde, Ulmenallee 5-11, D-49214 Bad Rothenfelde, Germany.

Background: A rare, but serious, complication following transcatheter aortic valve replacement (TAVR) is the occurrence of an iatrogenic ventricular septal defect (VSD).

Case Summary: We describe a case of an 80-year-old female who was referred with severe aortic stenosis for TAVR. Following thorough evaluation, the heart team consensus was to proceed with implantation via a transapical approach of an ACURATE neo M 25 mm valve (Boston Scientific, Natick, MA, USA). Read More

Semin Thorac Cardiovasc Surg 2021 May 15. Epub 2021 May 15.

Department of Cardiovascular Surgery, College of Medicine, Seoul National University, Boston Children's Hospital, Boston, Massachusetts. Electronic address:

Patients with borderline hypoplastic right or left ventricle and VSD may be candidates for either single ventricle palliation or staged ventricular recruitment (SVR) followed by eventual biventricular conversion. Components of SVR include restriction of atrial septal defects (ASD) without ventricular septal defects (VSD) closure and addition of accessory pulmonary blood flow. This study evaluated the impact of ASD restriction on ventricular growth and function. Read More

J Cardiol Cases 2021 May 23;23(5):198-201. Epub 2020 Nov 23.

Cancer and Molecular Research Center, Department of Pathology, Ghaem Hospital, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

Lymphoma is one of the most common tumors with the risk of cardiac metastasis. The pattern of cardiac involvement is usually as focal masses. As early diagnosis of lymphoma plays a crucial role in its response to treatment and patient survival longevity, we report a rare case of cardiac lymphoma with diffuse cardiac involvement and acquired pulmonary stenosis. Read More

Semin Thorac Cardiovasc Surg 2021 May 10. Epub 2021 May 10.

Department of Cardiac Surgery, University Hospital, University of Zürich, Switzerland.

Valved allografts and xenografts for reconstruction of the right ventricular outflow tract (RVOT) lack durability and do not grow. We report the first clinical use of a completely bioabsorbable valved conduit (Xeltis pulmonary valve - XPV) in children. Twelve children (six male), median age five (two to twelve) years and median weight 17 (10 to 43) kg, underwent RVOT reconstruction with the XPV. Read More

Cureus 2021 Apr 7;13(4):e14344. Epub 2021 Apr 7.

Medicine, Mercy Health St. Vincent Medical Center, Toledo, USA.

Introduction In recent decades, transcatheter aortic valve implantation (TAVI) has become a treatment of choice for aortic stenosis. The purpose of this study was to evaluate predictors of mortality in patients undergoing TAVI. Methods The National Inpatient Sample database from the year 2011 to 2018 was used to identify all patients undergoing TAVI during the study period. Read More

J Thorac Cardiovasc Surg 2021 May 7. Epub 2021 May 7.

Semin Thorac Cardiovasc Surg 2021 May 8. Epub 2021 May 8.

Departments of Cardiothoracic Surgery, Stanford University School of Medicine; Pediatrics, Stanford University School of Medicine. Electronic address:

There is limited information about durability of large diameter porcine bioprostheses implanted for pulmonary valve replacement (PVR). We studied patients who underwent surgical PVR from 2002-2019 with a stented porcine bioprosthetic valve (BPV) with a labeled size ≥27 mm. The primary outcome was freedom from reintervention. Read More

Eur J Pediatr 2021 May 10. Epub 2021 May 10.

Department of Paediatric Cardiac Surgery, Alder Hey Children's Hospital, Liverpool, UK.

Congenital anomalies of the aortic valve frequently necessitate intervention in childhood. The most common aortic valve pathologies present in childhood are aortic stenosis and insufficiency. Presentation of aortic valve disease depends on severity and presence of concomitant syndromes and valvular disorders. Read More

Catheter Cardiovasc Interv 2021 May 7. Epub 2021 May 7.

Department of Cardiology, Rabin Medical Center, Petach Tikva, affiliated with Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Objectives: To evaluate the use and outcomes of percutaneous mechanical circulatory support (pMCS) utilized during transcatheter aortic valve implantation (TAVI) from high-volume centers.

Methods And Results: Our international multicenter registry including 13 high-volume TAVI centers with 87 patients (76.5 ± 11. Read More

J Invasive Cardiol 2021 Jun 6;33(6):E431-E442. Epub 2021 May 6.

Division of Interventional Cardiology of MedStar, Cardiovascular Research Network at MedStar Washington Hospital Center, 110 Irving Street, Suite 4B-1, Washington, D.C., 20010.

Aim: To evaluate gender differences and mortality trends in a population undergoing transcatheter aortic valve implantation (TAVI) and to analyze the correlates to all-cause mortality at follow-up.

Methods: The study comprises a prospective cohort of 592 TAVI patients (53.4% female) treated between 2008 and 2018. Read More

Circ Heart Fail 2021 May 6;14(5):e008618. Epub 2021 May 6.

Department of Cardiology, Angiology and Intensive Care, Medicine Medical Clinic II, University Heart Center Lübeck, Germany.

Circ Heart Fail 2021 May 6;14(5):e008397. Epub 2021 May 6.

Department of Anesthesiology, Keck School of Medicine, University of Southern California, Los Angeles.

J Vet Cardiol 2021 Apr 2;35:124-129. Epub 2021 Apr 2.

University of Chicago, Pediatric Cardiology, Chicago, IL, USA.

A 4-year-old male neutered English bulldog presented for heart murmur evaluation. Echocardiography identified severe pulmonic stenosis (an echocardiography-derived transpulmonary pressure gradient of 100 mmHg), and computed tomography confirmed the presence of an anomalous coronary artery with a prepulmonic course of the left coronary artery arising from the right coronary ostium. Before artificial pulmonic valve implantation, a coronary compression test was performed. Read More

Eur J Cardiothorac Surg 2021 May;59(5):968-977

Department of Cardiothoracic Surgery, Leiden University Medical Center, Leiden, Netherlands.

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Objectives: The objective of this study was to assess our 43-year experience with arterial switch operation (ASO) for transposition of the great arteries (TGA) by analysing cardiac outcome measures (hospital and late mortality, reoperations and catheter interventions, significant coronary artery obstruction) and to identify risk factors for reoperation and catheter interventions.

Methods: A total of 490 patients who underwent ASO for TGA from 1977 to 2020 were included in this retrospective, single-centre study. Data on reoperation and catheter intervention of hospital survivors were estimated by the Kaplan-Meier method and compared using a long-rank test. Read More

World J Pediatr Congenit Heart Surg 2021 May;12(3):411-413

Division of Cardiovascular Surgery, 8404Children's National Health System, Washington, DC, USA.

Background: Stented bioprosthesis implant at surgical pulmonary valve replacement (PVR) ideally should be 25 to 27 mm to facilitate future percutaneous PVR. This often requires accommodating 35 to 37 mm diameter sewing ring in the pulmonary position and requires anterior patch augmentation of the right ventricular outflow tract (RVOT). We present a novel "interposition" technique of PVR that allows upsizing the valve without RVOT patch augmentation. Read More

J Med Case Rep 2021 May 4;15(1):225. Epub 2021 May 4.

Tulubolo General Hospital, Tulu Bolo, Ethiopia.

Background: Among cardiac causes for postpartum maternal collapse, severe mitral stenosis is not listed as a potential cause in current literature. We report a rare case of severe mitral stenosis that presented with severe hypoxia and maternal decompensation in early postpartum period for the first time. A 30-year-old para 2, abortus 1, Ethiopian woman developed severe hypoxia and rapid deterioration on her sixth postoperative day after cesarean delivery for fetal bradycardia with a good fetal outcome. Read More

Swiss Med Wkly 2021 Mar 29;151:w20491. Epub 2021 Mar 29.

Woman-Mother-Child Department, Lausanne University Hospital and University of Lausanne, Switzerland.

Aims: To describe the early results of complete repair of tetralogy of Fallot (TOF) in children older than one year of age.

Methods: We identified all patients older than one year of age who underwent TOF repair between 2007 and 2017. Data collected included type of surgical repair, survival at 30 days after surgery, reintervention within 30 days of surgery, length of stay in the intensive care unit (ICU), length of stay in hospital, and degree of residual right ventricular outflow tract (RVOT) stenosis and pulmonary insufficiency 30 days after surgery. Read More