35,098 results match your criteria Pulmonic Valve


Hybrid approach for management of end-stage heart failure in complex congenital heart disease.

Int J Artif Organs 2022 Jun 28:3913988221109285. Epub 2022 Jun 28.

Pediatric Cardiac Surgery Unit, Department of Cardio-Thoracic-Vascular Sciences and Public Health, University of Padova, Padova, Italy.

Management of end-stage heart failure (ESHF) in children with congenital heart disease is challenging. We report a step-by-step hybrid procedure (transcatheter pulmonary valve and left mechanical assist device implantations) in a child with ESHF after repair of tetralogy of Fallot, as an effective bridge to transplant strategy. Read More

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KMT2D-NOTCH Mediates Coronary Abnormalities in Hypoplastic Left Heart Syndrome.

Circ Res 2022 Jun 28:101161CIRCRESAHA122320783. Epub 2022 Jun 28.

Perinatal Institute, Division of Pulmonary Biology, Cincinnati Children's Hospital Medical Center, OH (Z.Y., Z.L., V.P.-G., M.G., Y.M., M.G.).

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Transcatheter Pulmonary Valve Replacement from Autologous Pericardium with a Self-Expandable Nitinol Stent in an Adult Sheep Model.

J Vis Exp 2022 Jun 8(184). Epub 2022 Jun 8.

Department of Pediatric Cardiology and Congenital Heart Disease, Charité University Medicine Berlin; Department of Pediatric Cardiology and Congenital Heart Disease, Deutsches Herzzentrum Berlin; DZHK (German Centre for Cardiovascular Research) and BMBF (German Ministry of Education and Research); BIH (Berlin Institute of Health); BCRT (BIH Center of Regenerative Therapies);

Transcatheter pulmonary valve replacement has been established as a viable alternative approach for patients suffering from right ventricular outflow tract or bioprosthetic valve dysfunction, with excellent early and late clinical outcomes. However, clinical challenges such as stented heart valve deterioration, coronary occlusion, endocarditis, and other complications must be addressed for lifetime application, particularly in pediatric patients. To facilitate the development of a lifelong solution for patients, transcatheter autologous pulmonary valve replacement was performed in an adult sheep model. Read More

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Echocardiographic evaluation of total anomalous pulmonary venous connection: Comparison of obstructed and unobstructed type.

Medicine (Baltimore) 2022 Jun 24;101(25):e29552. Epub 2022 Jun 24.

Department of Radiology, Hunan Children's Hospital, University of South China, Changsha, China.

Abstract: This study aims to compare the differences between obstructed and unobstructed total anomalous pulmonary venous connection (TAPVC) using echocardiography, and to evaluate the clinical and echocardiographic parameters associated with pulmonary venous obstruction (PVO).We conducted a retrospective study of 70 patients with TAPVC between 2014 and 2019. The morphologic and hemodynamic echocardiographic parameters of patients were observed and measured, and the parameters between obstructed and unobstructed TAPVC were compared. Read More

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Conversion of Norwood-Rastelli Procedure to "Anatomic" Biventricular Circulation With Takedown of Aortopulmonary Amalgamation After Aortic Valve Growth.

World J Pediatr Congenit Heart Surg 2022 Jul;13(4):503-507

Department of Cardiovascular Surgery, 38088Kitasato University School of Medicine, Kanagawa, Japan.

The pathways for biventricular repair of hypoplastic aortic arch with ventricular septal defect, small aortic valve, and normal-sized left ventricle vary depending on the disease spectrum. We report a case of an infant who underwent a staged Norwood-Rastelli procedure for aortic stenosis (bicuspid aortic valve), hypoplastic aortic arch, and coarctation of the aorta with ventricular septal defect and normal-sized left ventricle. Ten years after the initial surgery, normal circulatory physiology was achieved with a takedown of the aortopulmonary amalgamation and VSD closure. Read More

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Pediatric Surgical Pulmonary Valve Replacement Outcomes After Implementation of a Clinical Pathway.

World J Pediatr Congenit Heart Surg 2022 Jul;13(4):420-425

Department of Pediatrics, Division of Cardiology, 23333Loma Linda University Children's Hospital, Loma Linda, CA, USA.

Background: Standardization of perioperative care can reduce resource utilization while improving patient outcomes. We sought to describe our outcomes after the implementation of a perioperative clinical pathway for pediatric patients undergoing elective surgical pulmonary valve replacement and compare these results to previously published national benchmarks.

Methods: A retrospective single-center descriptive study was conducted of all pediatric patients who underwent surgical pulmonary valve replacement from 2017 through 2020, after the implementation of a clinical pathway. Read More

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Technique for Neo-Pulmonary Valve Creation With Living Tissue for Repair of Atrioventricular Septal Defect and Tetralogy of Fallot.

World J Pediatr Congenit Heart Surg 2022 Jul;13(4):499-502

Department of Surgery, Division of Cardiothoracic Surgery, Section of Pediatric Cardiothoracic Surgery, 12275Washington University School of Medicine, St. Louis Children's Hospital, St. Louis, Missouri, USA.

Long-standing effects of pulmonary regurgitation after transannular patch repair in Tetralogy of Fallot (ToF) can be especially deleterious in the setting of combined ToF and complete atrioventricular septal defect (CAVSD). We present a technique for a complete repair of combined ToF/CAVSD using right atrial appendage tissue to create a competent neo-pulmonary valve. This technique provides advantages of right heart protection via pulmonary valve competence and the use of living tissue capable of growth with the patient, potentially obviating the need for repeat interventions. Read More

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Inhaled Steroids, Sex and Emphysema Index - Clinical Parameters with Impact on the Effectiveness of Valve Implantation in Patients with Severe Emphysema.

Int J Chron Obstruct Pulmon Dis 2022 20;17:1423-1430. Epub 2022 Jun 20.

Pneumology and Critical Care Medicine, Thoraxklinik at University of Heidelberg, Heidelberg, Germany.

Aims And Objectives: Many patients with chronic obstructive lung disease suffer from emphysema. Valve implantation may be a reasonable method in patients presenting advanced emphysema and absent interlobar collateral ventilation (CV). However, other clinical parameters influencing the effectiveness of endoscopic lung volume reduction (ELVR) are not well known. Read More

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A combination of severe complications in a case of infective endocarditis: Dehiscence of prosthetic aortic valve, aortic dissection, pseudoaneurysm, and hematoma causing right ventricular collapse.

Echocardiography 2022 Jun 27. Epub 2022 Jun 27.

Department of Cardiovascular Surgery, Basaksehir Cam & Sakura City Hospital, Istanbul, Turkey.

Prosthetic valve endocarditis with mechanical complications causing pulmonary edema is fatal, therefore it needs to be diagnosed early and should be treated surgically in emergency setting. Transesophageal echocardiogram is crucial for recognizing the mechanical complications, which can be encountered on daily practice, but the coexistence of complications occurring on different mechanism is rather uncommon. Herein, we report a 21-year-old gentleman presenting with acute heart failure, whose imaging tests showed a combination of dehiscence of mechanical aortic valve prosthesis, aortic dissection, pseudoaneurysm, and hematoma causing right ventricular collapse. Read More

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Long-Term Results after Fallot Repair.

Thorac Cardiovasc Surg 2022 Dec 25;70(S 03):e7-e14. Epub 2022 Jun 25.

Universitäts-Kinderspital Zürich, Zurich, Switzerland.

Background:  The aim of this study was to evaluate the long-term outcome and freedom from pulmonary valve replacement (PVR) after initial repair of tetralogy of Fallot (TOF).

Patients And Methods:  The cohort of 306 patients treated between 1980 and 2017 was divided into anatomical subgroups according to the diagnosis of TOF-pulmonary stenosis, TOF-pulmonary atresia and TOF-double outlet right ventricle. Patients were treated with transannular patch (TAP), valve sparing repair (VSR), or conduits from the right ventricle to the pulmonary arteries (RVPA conduits). Read More

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December 2022

Pulmonary Atresia with Intact Ventricular Septum: Midterm Outcomes from a Multicenter Cohort.

Pediatr Cardiol 2022 Jun 25. Epub 2022 Jun 25.

Division of Cardiology, Department of Pediatrics, Shawn Jenkins Children's Hospital, Medical University of South Carolina, Charleston, SC, USA.

Contemporary multicenter data regarding midterm outcomes for neonates with pulmonary atresia with intact ventricular septum are lacking. We sought to describe outcomes in a contemporary multicenter cohort, determine factors associated with end-states, and evaluate the effect of right ventricular coronary dependency and coronary atresia on transplant-free survival. Neonates treated during 2009-2019 in 19 United States centers were reviewed. Read More

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Real-life outcomes and readmissions after a TAVI procedure in a Glasgow population.

Br J Cardiol 2021 1;28(3):37. Epub 2021 Sep 1.

Consultant Cardiologist Department of Cardiology, Queen Elizabeth University Hospital, 1345 Govan Road, Glasgow, G51 4TF.

Transcatheter aortic valve implantation (TAVI) is a routine procedure for patients with symptomatic severe aortic stenosis who are deemed inoperable or high-risk surgical candidates. The aim of this study was to examine real-world data on death and readmission rates in patients following the procedure. Electronic health records for patients who underwent TAVI between April 2015 and November 2018 were reviewed. Read More

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September 2021

Outpatient parenteral antimicrobial therapy (OPAT) service is associated with inpatient-bed cost savings.

Br J Cardiol 2021 1;28(3):38. Epub 2021 Sep 1.

Consultant Cardiologist Department of Cardiology, Royal Stoke University Hospital, Newcastle Road, Stoke-on-Trent, ST4 6QG.

In a cardiology department, there are some patients that require long-term antibiotics, such as those with infective endocarditis or infected prosthetic devices. We describe our experience with intravenous antibiotic therapy for patients with cardiology diagnoses who require a period of antibiotics in our outpatient service during the period of the COVID-19 pandemic. A total of 15 patients were selected to have outpatient antibiotic therapy (age range 36 to 97 years, 60% male). Read More

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September 2021

Echocardiography in Prone Positioned Critically Ill Patients: A Wealth of Information from a Single View.

Diagnostics (Basel) 2022 Jun 14;12(6). Epub 2022 Jun 14.

Department of Anesthesia, Intensive Care Unit and Pain Therapy, IRCCS Humanitas Clinical and Research Center, 20089 Milan, Italy.

In critically ill patients, standard transthoracic echocardiography (TTE) generally does not facilitate good image quality during mechanical ventilation. We propose a prone-TTE in prone positioned patients, which allows clinicians to obtain a complete apical four-chamber (A-4-C) view. A basic cardiac assessment can be performed in order to evaluate right ventricle function and left ventricle performance, even measuring objective parameters, i. Read More

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Prevalence of Reticulocytosis in the Absence of Anemia in Dogs with Cardiogenic Pulmonary Edema Due to Myxomatous Mitral Valve Disease: A Retrospective Study.

Vet Sci 2022 Jun 14;9(6). Epub 2022 Jun 14.

Department of Veterinary Clinical Pathology and Bio-Safety Research Institute, College of Veterinary Medicine, Chonbuk National University, Jeonju 54596, Korea.

Myxomatous mitral valve disease (MMVD) is the most common heart disease in small breed dogs. Dogs with MMVD commonly show clinical signs of dyspnea due to cardiogenic pulmonary edema (CPE). Reticulocytosis in the absence of anemia (RAA) is a hematological finding in hypoxic conditions. Read More

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Ductus Arteriosus Stenting in Newborns - Transcatheter Approach as a Bridge Therapy for Corrective Surgery.

Maedica (Bucur) 2022 Mar;17(1):205-210

"Marie Curie" Emergency Children's Hospital, Bucharest, Romania.

Duct-dependent congenital heart disease requires attentive therapeutic management since the only source of pulmonary blood flow in newborns is provided by the patent ductus arteriosus. The patency of the duct is the main objective in the first hours of life and it is guaranteed by prostaglandin E1 infusion, but it is not a long-term solution for this type of cardiac malformation. In order to augment pulmonary blood, there are two types of interventions that can be performed: a classical surgical shunt or stenting of the ductus arteriosus, a fairly new alternative to cardiac palliative surgery. Read More

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Mitral valve repair in papillary muscle rupture.

Ann Cardiothorac Surg 2022 May;11(3):281-289

Department of Cardiothoracic Surgery, Maastricht University Medical Centre, Maastricht, The Netherlands.

Papillary muscle rupture (PMR) is a significant mechanical complication following myocardial infarction (MI), a condition associated with a high mortality. It results in severe mitral valve regurgitation (MR), often accompanied by cardiogenic shock and pulmonary edema, requiring both emergent medical treatment and surgical intervention. Surgical treatment includes either chordal sparing mitral valve replacement or mitral valve repair, which is associated with a high mortality. Read More

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Treatment of a pneumatocele in a COVID-19 patient with endobronchial valves.

BMJ Case Rep 2022 Jun 21;15(6). Epub 2022 Jun 21.

Department of Cardio-thoracic Surgery, Oslo University Hospital, Oslo, Norway.

A man in his 40s was admitted to his local hospital 6 days after the first vague symptoms of COVID-19. His general condition deteriorated, and he was treated in the intensive care unit but did not require mechanical ventilation. During his recovery, he experienced a cough spell, after which his dyspnoea recurred and rapidly increased. Read More

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Treatment of severe fetal Ebstein's anomaly with prenatal non-steroidal anti-inflammatory therapy.

Fetal Diagn Ther 2022 Jun 21. Epub 2022 Jun 21.

Introduction: Prenatally diagnosed Ebstein's anomaly with tricuspid valve dysplasia (EA/TVD) is a rare and high-risk congenital heart malformation with limited effective treatments. We report a case of severe fetal EA with hydrops treated with modest doses of non-steroidal anti-inflammatory drug (NSAID) therapy, resulting in reversal of hydrops and a favorable fetal outcome.

Case Presentation: Fetal heart defects included an inferiorly displaced tricuspid valve, severe tricuspid regurgitation, significantly dilated right atrium, and hypoplastic pulmonary valve with moderate regurgitation resulting in a circular shunt across the ductus arteriosus. Read More

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The removal of floating right heart thrombi and pulmonary embolus using AngioJet device and venoarterial extracorporeal membrane oxygenation: a case report.

Ann Transl Med 2022 May;10(10):612

Department of Operation Room, Taizhou Hospital of Zhejiang Province, Zhejiang University, Linhai, China.

Background: Floating right heart thrombi (FRHTS), known as thrombi in transit, are usually located in the atrium or ventricle. Generally, it occurs in patients with pulmonary embolism (PE) and dyspnea, chest pain, syncope and palpitations are the most common symptoms on presentation. The mortality of patients with FRHTS is higher than that of those without FRHTS. Read More

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Invasive Hemodynamic Assessment and Procedural Success of Transcatheter Tricuspid Valve Repair-Important Factors for Right Ventricular Remodeling and Outcome.

Front Cardiovasc Med 2022 2;9:891468. Epub 2022 Jun 2.

Division of Cardiology, Department of Internal Medicine II, Medical University of Vienna, Vienna, Austria.

Introduction: Severe tricuspid regurgitation (TR) is a common condition promoting right heart failure and is associated with a poor long-term prognosis. Transcatheter tricuspid valve repair (TTVR) emerged as a low-risk alternative to surgical repair techniques. However, patient selection remains controversial, particularly regarding the benefits of TTVR in patients with pulmonary hypertension (PH). Read More

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Pulmonary Vasculature Responsiveness to Phosphodiesterase-5A Inhibition in Heart Failure With Reduced Ejection Fraction: Possible Role of Plasma Potassium.

Front Cardiovasc Med 2022 26;9:883911. Epub 2022 May 26.

Institute for Clinical and Experimental Medicine (IKEM), Prague, Czechia.

Introduction: Phosphodiesterase-5a inhibition (PDE5i) leads to favorable changes in pulmonary hemodynamic and cardiac output (CO) in patients with advanced heart failure (HF) and reduced ejection fraction (HFrEF). The hemodynamic response to PDE5i could be heterogeneous and the clinical variables associated with these changes are scarcely investigated.

Materials And Methods: Of 260 patients with advanced HFrEF referred for advanced therapies [cardiac transplant/left ventricular assist device (LVAD)], 55 had pulmonary hypertension (PH) and fulfilled the criteria for the PDE5i vasoreactivity test. Read More

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Models and Techniques to Study Aortic Valve Calcification , and . An Overview.

Front Pharmacol 2022 2;13:835825. Epub 2022 Jun 2.

Department of Molecular Medicine, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.

Aortic valve stenosis secondary to aortic valve calcification is the most common valve disease in the Western world. Calcification is a result of pathological proliferation and osteogenic differentiation of resident valve interstitial cells. To develop non-surgical treatments, the molecular and cellular mechanisms of pathological calcification must be revealed. Read More

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Major adverse cardiovascular events following acute coronary syndrome in patients with bipolar disorder.

Int J Cardiol 2022 Jun 15. Epub 2022 Jun 15.

Department of Cardiology, Aalborg University Hospital, Aalborg, Denmark; Department of Clinical Medicine, Aalborg University, Aalborg, Denmark. Electronic address:

Background: Persons with bipolar disorder (BD) have a higher cardiovascular mortality compared to the general population, partially explained by the increased burden of cardiovascular risk factors. Research regarding outcomes following acute coronary syndrome (ACS) in this population remains scarce.

Design: This Danish register-based study included patients diagnosed with BD and ACS in the period between January 1st, 1995, to December 31st, 2013. Read More

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Non-platelet thromboxane generation is associated with impaired cardiovascular performance and mortality in heart failure.

Am J Physiol Heart Circ Physiol 2022 Jun 17. Epub 2022 Jun 17.

University of Massachusetts Medical School, Worcester, MA, United States.

Background: Non-platelet thromboxane generation, stimulated largely by oxidative stress, is a novel mortality risk factor in individuals with coronary artery disease. Though inversely associated with left ventricular ejection fraction (LVEF), a potential role in the pathobiology of heart failure (HF) remains poorly defined.

Methods: Non-platelet thromboxane generation and oxidative stress were assessed by measuring urine thromboxane B metabolites (TXB-M) and 8-isoPGF by ELISA in 105 subjects taking aspirin undergoing right heart catheterization for evaluation of HF, valve disease or after transplantation. Read More

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Anesthetic management for cesarean section in parturient with an uncorrected single ventricle: A case report and literature review.

Medicine (Baltimore) 2022 Jun 17;101(24):e29421. Epub 2022 Jun 17.

Department of Anesthesiology, Affiliated Hospital of North Sichuan Medical College, Nanchong, China.

Rationale: Patients with a single ventricle, who have not undergone surgery, reportedly have a lower survival rate. Furthermore, multiple pregnancies are rare among these females. We reported a case of anesthesia management of cesarean section in an uncorrected single-ventricular multi-pregnancy woman and review the anesthesia management of the published similar cases. Read More

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Where is the Thrombus ? Mural Ascending Aortic Thrombus with Embolic Events in a Patient with Recent COVID 19 Infection.

J Community Hosp Intern Med Perspect 2022 2;12(3):83-85. Epub 2022 May 2.

Department of Cadiology, Trinitas Regional Medical Center, Elizabeth, NJ, USA.

The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has triggered a global health pandemic that led to substantial morbidity and mortality worldwide. The virus has been known to predominantly cause severe hypoxemic respiratory failure but there have been multiple reports of extra-pulmonary manifestations. Additionally, there has been increasing evidence of COVID-19 hyper-coagulability. Read More

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Multi-spectrum robotic cardiac surgery: Early outcomes.

JTCVS Tech 2022 Jun 19;13:74-82. Epub 2022 Feb 19.

Department of Cardiothoracic Surgery, University of Chicago Medicine, Chicago, Ill.

Objective: The robotic cardiac surgery program at our current institution began in 2013 with an experienced and dedicated team. This review analyzes early outcomes in the first 1103 patients.

Methods: We reviewed all robotic procedures between July 2013 and February 2021. Read More

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Percutaneous Large Thrombus and Vegetation Evacuation in the Catheterization Laboratory.

Interv Cardiol Clin 2022 Jul;11(3):349-358

Section of Cardiology, Department of Internal Medicine, Banner University Medical Center, Sarver Heart Center, 1501 North Campbell Avenue, Tucson, AZ 85724, USA.

Intracardiac and intravascular thrombi are associated with significant morbidity and mortality. Although surgery remains the gold standard treatment option, these patients often have multiple comorbidities that can make surgical options challenging. With advancements in catheter-based technologies, there are now percutaneous treatment options for these patients. Read More

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