8,264 results match your criteria Pulmonic Regurgitation


Ministernotomy aortic valve surgery in patients with prior patent mammary artery grafts after coronary artery bypass grafting.

Eur J Cardiothorac Surg 2019 Jan 10. Epub 2019 Jan 10.

Department of Cardiothoracic Surgery, Lankenau Medical Center, Wynnewood, PA, USA.

Objectives: Patients with patent internal thoracic artery (ITA) grafts after prior coronary artery bypass grafting surgery who require aortic valve replacement (AVR) pose unique technical challenges for safe and optimal myocardial protection. The purpose of this study is to review our short- and long-term outcomes with redo minimally invasive AVR in patients with patent in situ ITA grafts.

Methods: From 2008 to 2016, 48 patients with at least 1 patent in situ mammary artery graft underwent minimally invasive AVR. Read More

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https://academic.oup.com/ejcts/advance-article/doi/10.1093/e
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http://dx.doi.org/10.1093/ejcts/ezy442DOI Listing
January 2019
1 Read

Effect of acute volume overload on echocardiographic indices of right ventricular function and dyssynchrony assessed by use of speckle tracking echocardiography in healthy dogs.

Am J Vet Res 2019 Jan;80(1):51-60

OBJECTIVE To determine the relationship between acute volume overload and echocardiographic indices of right ventricular (RV) function and dyssynchrony in healthy dogs. ANIMALS 7 healthy Beagles. PROCEDURES Right heart catheterization and echocardiography were performed in 7 healthy anesthetized Beagles at baseline and after induction of volume overload. Read More

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https://avmajournals.avma.org/doi/10.2460/ajvr.80.1.51
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http://dx.doi.org/10.2460/ajvr.80.1.51DOI Listing
January 2019
2 Reads

Early Outcomes of Cardiac Surgery in Patients with Noonan Syndrome.

Semin Thorac Cardiovasc Surg 2018 Dec 18. Epub 2018 Dec 18.

Departments of Cardiovascular Surgery, Mayo Clinic, Rochester, MN.

Objective: There is a paucity of cardiac surgery outcomes data for patients with Noonan syndrome (NS). Our objective was to evaluate early results in these patients.

Methods: Between January 1999-December 2015, 29 patients (18 males, 62%) with NS underwent cardiac surgery at our institution. Read More

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http://dx.doi.org/10.1053/j.semtcvs.2018.12.004DOI Listing
December 2018
1 Read

Double Valve Failure Due to Perceval Sutureless Aortic Valve Migration.

J Heart Valve Dis 2018 Jan;27(1):124-126

Cardiac Surgery Unit, Heart Center, Grande Ospedale Metropolitano 'Bianchi-Melacrino-Morelli', Reggio Calabria, Italy.

A 76-year-old woman was admitted to the authors' hospital with pulmonary edema five months after the successful implantation of a Perceval sutureless aortic valve (Sorin Group Srl, Saluggia, Italy). Both echocardiography and computed tomography scanning demonstrated migration of the aortic valve into the left ventricle, causing severe aortic and mitral (secondary) insufficiency. Following heart team discussions, the sutureless valve was replaced with a standard bioprosthesis (Perimount, Magna Ease; Edwards Lifesciences, Irvine, California, USA) with spontaneous restoration of native mitral valve competence. Read More

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January 2018
1 Read

A rare cause of ischemic stroke: cardiac myxoma. Case report and review of literature.

Rom J Morphol Embryol 2018 ;59(3):903-909

Department of Internal Medicine, University of Medicine and Pharmacy of Craiova, Romania;

A 46-year-old female diagnosed several years ago with arterial hypertension and an ischemic stroke with significant recovery was admitted for dyspnea on usual physical activity and fatigue. Physical examination revealed signs of heart failure with crackles on both lung bases, distented jugular veins, accentuated pulmonic valve closure (P2) and tricuspid regurgitation murmur. Echocardiography identified a large tumor in the left atrium, suggestive of atrial myxoma, which caused a severe functional mitral stenosis and produced severe pulmonary hypertension. Read More

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January 2019
1 Read

Specific features and survival of French bulldogs with congenital pulmonic stenosis: a prospective cohort study of 66 cases.

J Vet Cardiol 2018 Dec 18;20(6):405-414. Epub 2018 Oct 18.

Department of Biostatistics and Clinical Epidemiology, Université Paris-Est, Ecole Nationale Vétérinaire D'Alfort, 7 Avenue Du Général de Gaulle, 94704, Maisons-Alfort cedex, France.

Introduction: The objectives of this study were to characterize the epidemiological, clinical, and echocardiographic features of French bulldogs (FBs) with congenital pulmonic stenosis and document their survival times and risk factors for cardiac death (CD).

Animals: This study included 66 FBs with congenital pulmonic stenosis.

Methods: Prospective cohort study including a survival analysis to assess time to CD. Read More

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http://dx.doi.org/10.1016/j.jvc.2018.09.001DOI Listing
December 2018
1 Read

Altered biventricular hemodynamic forces in patients with repaired tetralogy of Fallot and right ventricular volume overload because of pulmonary regurgitation.

Am J Physiol Heart Circ Physiol 2018 Dec 28;315(6):H1691-H1702. Epub 2018 Sep 28.

Lund University, Department of Clinical Sciences, Lund, Clinical Physiology, Skåne University Hospital , Sweden.

Intracardiac hemodynamic forces have been proposed to influence remodeling and be a marker of ventricular dysfunction. We aimed to quantify the hemodynamic forces in patients with repaired tetralogy of Fallot (rToF) to further understand the pathophysiological mechanisms as this could be a potential marker for pulmonary valve replacement (PVR) in these patients. Patients with rToF and pulmonary regurgitation (PR) > 20% ( n = 18) and healthy control subjects ( n = 15) underwent MRI, including four-dimensional flow. Read More

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http://dx.doi.org/10.1152/ajpheart.00330.2018DOI Listing
December 2018
1 Read

Percutaneous pulmonary valve implantation as an alternative to repeat open-heart surgery for patients with pulmonary outflow obstruction: a reality in Singapore.

Singapore Med J 2018 Nov 29. Epub 2018 Nov 29.

Department of Pediatrics, National University of Singapore, Singapore.

Right ventricle to pulmonary artery (RV-PA) conduits have been used for the surgical repair of congenital heart defects. These conduits frequently become stenosed or develop insufficiency with time, necessitating reoperations. Percutanous pulmonary valve implantation (PPVI) can delay the need for repeated surgeries in patients with congenital heart defects and degenerated RV-PA conduits. Read More

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http://www.smj.org.sg/sites/default/files/CS-2017-047-epub.p
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http://dx.doi.org/10.11622/smedj.2018141DOI Listing
November 2018
6 Reads

Pulmonary effects on exercise testing in tetralogy of Fallot patients repaired with a transannular patch.

Cardiol Young 2018 Nov 26:1-7. Epub 2018 Nov 26.

The Heart Institute,Cincinnati Children's Hospital Medical Center,Cincinnati, OH,USA.

Background: A transannular patch is often used in the contemporary surgical repair of tetralogy of Fallot. This can lead to significant pulmonary insufficiency and increased right ventricular volumes and ultimately pulmonary valve replacement. Cardiopulmonary exercise testing is used to assess exercise capacity in tetralogy of Fallot patients before pulmonary valve replacement. Read More

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http://dx.doi.org/10.1017/S1047951118001920DOI Listing
November 2018
7 Reads

Comparison Of The Efficacy Of Sildenafil Alone Versus Sildenafil Plus Bosentan In Newborns With Persistent Pulmonary Hypertension.

J Ayub Med Coll Abbottabad 2018 Jul-Sep;30(3):333-336

Forensic Medicine Ayub Medical College, Abbottabad, Pakistan.

Background: Persistent pulmonary hypertension is a serious disease among new-borns. Inhaled nitric oxide is first line of therapy along with extracorporeal membrane oxygenation. Pulmonary vasodilators such as sildenafil, bosentan and milrinone are also used to treat persistent pulmonary hypertension especially in resource limited centres where inhaled nitric oxide is not available. Read More

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January 2019
6 Reads

Prognostic Value of Atrial Fibrillation Inducibility in Patients Without History of Clinical Atrial Fibrillation.

J Atr Fibrillation 2018 Jun-Jul;11(1):1837. Epub 2018 Jun 30.

Department of Cardiology and Cardiovascular Diseases, Eberhard Karls University, Tübingen, Germany.

Purpose: During invasive electrophysiological studies (EPS), atrial fibrillation (AF) can be induced in patients without a history of AF. However, the prognostic value is not well evaluated in this population. Our aim was to investigate whether AF inducibility in those patients is associated with future clinical episodes of AF; whether non-inducibility is predictive of freedom from new-onset AF and finally, to examine clinical factors associated with inducibility. Read More

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http://dx.doi.org/10.4022/jafib.1837DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6207235PMC
June 2018
9 Reads

Parameters associated with therapeutic response using peritoneal dialysis for therapy refractory heart failure and congestive right ventricular dysfunction.

PLoS One 2018 19;13(11):e0206830. Epub 2018 Nov 19.

Department of Internal Medicine III, Clinical Division of Nephrology and Dialysis, Medical University of Vienna, Vienna, Austria.

Background: In patients with refractory heart failure (HF) peritoneal dialysis (PD) is associated with improved functional status and decrease in hospitalization. However, previous studies did not focus on right ventricular dysfunction as an important pathophysiologic component of cardiorenal syndrome.

Methods: In a prospective cohort study PD was started in 40 patients with refractory right HF (with/without left HF). Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0206830PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6242305PMC
November 2018
4 Reads

Toward predictive modeling of catheter-based pulmonary valve replacement into native right ventricular outflow tracts.

Catheter Cardiovasc Interv 2018 Nov 15. Epub 2018 Nov 15.

Division of Cardiology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.

Background: Pulmonary insufficiency is a consequence of transannular patch repair in Tetralogy of Fallot (ToF) leading to late morbidity and mortality. Transcatheter native outflow tract pulmonary valve replacement has become a reality. However, predicting a secure, atraumatic implantation of a catheter-based device remains a significant challenge due to the complex and dynamic nature of the right ventricular outflow tract (RVOT). Read More

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http://doi.wiley.com/10.1002/ccd.27962
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http://dx.doi.org/10.1002/ccd.27962DOI Listing
November 2018
8 Reads

Early outcomes of percutaneous pulmonary valve implantation using the Edwards SAPIEN 3 transcatheter heart valve system.

EuroIntervention 2018 Nov 13. Epub 2018 Nov 13.

Hôpital Marie Lannelongue, Le Plessis Robinson, France.

Aims: Multiple surgical revisions are often necessary in individuals with congenital heart defects affecting the RVOT or pulmonary valve. There are no multicentre data on the feasibility and safety of percutaneous pulmonary valve implantation using the SAPIEN 3 (S3) transcatheter heart valve.

Methods And Results: Pulmonic S3 is an observational registry of patients undergoing PPVI with the S3 valve across centres in Europe and Canada. Read More

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http://dx.doi.org/10.4244/EIJ-D-18-01035DOI Listing
November 2018
3 Reads
3.770 Impact Factor

Melody valve in mitral position: Complete fracture causing acute mitral stenosis in a child.

Catheter Cardiovasc Interv 2018 Oct 31. Epub 2018 Oct 31.

Division of Pediatric Cardiology, Mayo Clinic, Rochester, Minnesota.

We present a case of a 7-year-old boy with a history of multiple mitral valve interventions and subsequent Melody valve placement in the mitral position, who presented with acute mitral stenosis due to complete fracture of the Melody stent. He was born early with severe mitral and tricuspid insufficiency due to valvular dysplasia, and ended up with 4 sternotomies before the age of 2 due to mitral valve dysfunction and recurrent prosthetic valve thrombosis. He then developed mixed stenosis and regurgitation at age 6, and to avoid another sternotomy, valve-in-valve therapy with off-label use of a 20-mm Melody valve was done with hybrid procedure via trans-apical approach. Read More

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http://doi.wiley.com/10.1002/ccd.27683
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http://dx.doi.org/10.1002/ccd.27683DOI Listing
October 2018
2 Reads

Cardiac Valve Involvement in Takayasu Arteritis Is Common: A Retrospective Study of 1,069 Patients Over 25 Years.

Am J Med Sci 2018 Oct 30;356(4):357-364. Epub 2018 Jun 30.

Department of Cardiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

Background: Takayasu arteritis (TA) can involve the aortic root or cardiac valves, resulting in hemodynamic disorders. In this study, we focused on the prevalence and clinical characteristics of TA patients with valve regurgitation.

Materials And Methods: We retrospectively assessed the clinical data in the electronic medical records of 1,069 consecutive patients with TA admitted to Fuwai Hospital from January 1992 to August 2017. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00029629183023
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http://dx.doi.org/10.1016/j.amjms.2018.06.021DOI Listing
October 2018
6 Reads

Exercise-Stress Echocardiography and Effort Intolerance in Asymptomatic/Minimally Symptomatic Patients With Degenerative Mitral Regurgitation Combined Invasive-Noninvasive Hemodynamic Monitoring.

Circ Cardiovasc Imaging 2018 Sep;11(9):e007282

Department Cardiovascular Medicine, Hiroshima University Graduate School of Biomedical and Health Sciences, Japan.

Background Effort intolerance, measured objectively by reduced peak oxygen consumption (Vo), has been considered as an important prognosticator in degenerative mitral regurgitation (MR). However, its mechanism is unknown. Methods and Results In 25 asymptomatic/minimally symptomatic patients with grade III+ or greater degenerative MR undergoing semisupine invasive exercise testing, Doppler estimates and invasive measurement of systolic (SPAP) and mean pulmonary artery pressure (MPAP) and cardiac output (CO) were simultaneously obtained. Read More

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https://www.ahajournals.org/doi/10.1161/CIRCIMAGING.117.0072
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http://dx.doi.org/10.1161/CIRCIMAGING.117.007282DOI Listing
September 2018
7 Reads

Differences in Right Ventricular Physiologic Response to Chronic Volume Load in Patients with Repaired Pulmonary Atresia Intact Ventricular Septum/Critical Pulmonary Stenosis Versus Tetralogy of Fallot.

Pediatr Cardiol 2018 Oct 23. Epub 2018 Oct 23.

Division of Pediatric Cardiology, Children's Hospital Los Angeles, 4650 Sunset Blvd., Mailstop #34, Los Angeles, CA, 90027, USA.

Background: Patients with pulmonary atresia with intact ventricular septum and critical pulmonary stenosis (PAIVS/CPS) have wide variation in right ventricle (RV) size, systolic function, and diastolic function at birth. Establishment of antegrade pulmonary blood flow creates the potential for RV dilation from chronic pulmonary insufficiency. Future surgical decisions are based on RV size and function, largely supported by longitudinal studies of patients with Tetralogy of Fallot (TOF). Read More

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http://link.springer.com/10.1007/s00246-018-2009-2
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http://dx.doi.org/10.1007/s00246-018-2009-2DOI Listing
October 2018
9 Reads

Pulmonary valve insufficiency 12 years after high-velocity blunt chest trauma.

Eur J Cardiothorac Surg 2018 Oct 22. Epub 2018 Oct 22.

Department of Cardiac Surgery, Sana Herzchirurgie Stuttgart, Stuttgart, Germany.

The spectrum of cardiac injury due to blunt chest trauma may range from cardiac contusions with a clinically silent course to fatal cardiac wall rupture. Pulmonary valve insufficiency due to non-penetrating chest trauma is a rare entity. In this case, pulmonary valve insufficiency as a result of valve tear due to high-velocity blunt chest trauma required surgical replacement. Read More

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http://dx.doi.org/10.1093/ejcts/ezy353DOI Listing
October 2018
2 Reads

Outcomes after transaortic transcatheter aortic valve implantation: long-term findings from the European ROUTE.

Eur J Cardiothorac Surg 2018 Oct 20. Epub 2018 Oct 20.

Department of Internal Medicine III (Cardiology and Angiology) UKSH, Campus Kiel, Kiel, Germany.

Objectives: There is lack of data regarding the longer-term outcomes of patients undergoing transaortic (TAo) transcatheter aortic valve implantation (TAVI). We aimed to provide a contemporary snapshot of the types and frequencies of events in the year following TAo-TAVI.

Methods: The Registry of the Utilization of the TAo-TAVI approach using the Edwards SAPIEN Valve (ROUTE) is a multicentre, European, prospective, observational registry of aortic stenosis patients undergoing TAo-TAVI. Read More

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http://dx.doi.org/10.1093/ejcts/ezy333DOI Listing
October 2018
6 Reads
3.304 Impact Factor

Pulmonary Autograft Mitral Valve Replacement (Ross II): Long-Term Follow-Up of a US Center.

World J Pediatr Congenit Heart Surg 2018 11;9(6):645-650

1 Division of Thoracic and Cardiovascular Surgery, Indiana University School of Medicine, Indianapolis, IN, USA.

Background: Mitral valve replacement (MVR) with a pulmonary autograft (Ross II) may be a useful technique for pediatric and young adult patients who wish to avoid anticoagulation. Our aim was to evaluate the long-term outcomes of the Ross II procedure at our institution.

Methods: Patients undergoing the Ross II procedure between June 2002 and April 2008 were included. Read More

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http://journals.sagepub.com/doi/10.1177/2150135118792196
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http://dx.doi.org/10.1177/2150135118792196DOI Listing
November 2018
2 Reads

Long-term outcomes in patients who underwent surgical correction for atrioventricular septal defect.

Anatol J Cardiol 2018 Oct;20(4):229-234

Departmen of Pediatric Cardiology, Başkent University İstanbul Health and Education Hospital; İstanbul-Turkey.

Objective: The follow-up results of patients operated for atrioventricular septal defect (AVSD) during 1996-2016 at Başkent University are presented.

Methods: Data obtained from hospital records consists of preoperative echocardiographic and angiographic details, age and weight at surgery, operative details, Down syndrome presence, postoperative care details, early postoperative and latest echocardiographic findings and hospitalization for reintervention.

Results: A total of 496 patient-files were reviewed including 314 patients (63. Read More

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http://dx.doi.org/10.14744/AnatolJCardiol.2018.39660DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249524PMC
October 2018
1 Read

3-Year Outcomes of the Edwards SAPIEN Transcatheter Heart Valve for Conduit Failure in the Pulmonary Position From the COMPASSION Multicenter Clinical Trial.

JACC Cardiovasc Interv 2018 Oct;11(19):1920-1929

Sidra Cardiovascular Center of Excellence, Weill Cornell Medical College, Doha, Qatar.

Objectives: This study provides the 3-year follow-up results of the COMPASSION (Congenital Multicenter Trial of Pulmonic Valve Regurgitation Studying the SAPIEN Transcatheter Heart Valve) trial. Patients with moderate to severe pulmonary regurgitation and/or right ventricular outflow tract conduit obstruction were implanted with the SAPIEN transcatheter heart valve (THV).

Background: Early safety and efficacy of the Edwards SAPIEN THV in the pulmonary position have been established through a multicenter clinical trial. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S19368798183124
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http://dx.doi.org/10.1016/j.jcin.2018.06.001DOI Listing
October 2018
6 Reads

Altered biventricular hemodynamic forces in patients with repaired Tetralogy of Fallot and right ventricular volume overload due to pulmonary regurgitation.

Am J Physiol Heart Circ Physiol 2018 Sep 28. Epub 2018 Sep 28.

Lund University, Department of Clinical Sciences Lund, Clinical Physiology, Sweden.

Intracardiac hemodynamic forces have been proposed to influence remodeling and be a marker of ventricular dysfunction. We aimed to quantify the hemodynamic forces in repaired tetralogy of Fallot (rToF) patients to further understand the pathophysiological mechanisms as this could be a potential marker for pulmonary valve replacement (PVR) in these patients. Patients with rToF and PR>20% (n=18) and healthy controls (n=15) underwent magnetic resonance imaging (MRI) including 4D-flow. Read More

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http://dx.doi.org/10.1152/ajpheart.00330.2018DOI Listing
September 2018
2 Reads

Monocusp valve placement in children with tetralogy of Fallot undergoing repair with transannular patch: A functioning pulmonary valve does not improve immediate postsurgical outcomes.

Congenit Heart Dis 2018 Nov 27;13(6):935-943. Epub 2018 Sep 27.

Division of Pediatric Cardiothoracic Surgery, Medical College of Wisconsin, Herma Heart Institute at Children's Hospital of Wisconsin, Milwaukee, Wisconsin.

Introduction: In patients with tetralogy of Fallot (TOF), use of transannular patch (TAP) may be required in order to relieve significant right ventricular outflow tract obstruction, subsequently resulting in pulmonary insufficiency (PI). The monocusp valve has been used to temporarily reduce insufficiency in hopes to improve short and midterm outcomes. The purpose of this study was to assess for potential benefits of the monocusp valve in this subset of patients. Read More

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http://dx.doi.org/10.1111/chd.12670DOI Listing
November 2018
2 Reads

Role of Cardiac Magnetic Resonance Imaging in Valvular Heart Disease: Diagnosis, Assessment, and Management.

Curr Cardiol Rep 2018 Sep 26;20(11):119. Epub 2018 Sep 26.

Department of Medicine (Cardiovascular Division), University of Virginia Health System, 1215 Lee Street, PO Box 800158, Charlottesville, VA, 22908, USA.

Purpose Of Review: This article will review the current techniques in cardiac magnetic resonance imaging (CMR) for diagnosing and assessing primary valvular heart disease.

Recent Findings: The recent advancements in CMR have led to an increased role of this modality for qualifying and quantifying various native valve diseases. Phase-contrast velocity encoded imaging is a well-established technique that can be used to quantify aortic and pulmonic flow. Read More

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http://dx.doi.org/10.1007/s11886-018-1057-9DOI Listing
September 2018
6 Reads

Left atrial hemodynamics and left ventricular remodeling -predictors of outcomes after Transcatheter mitral valve repair with the MitraClip device.

Catheter Cardiovasc Interv 2019 Jan 23;93(1):128-133. Epub 2018 Sep 23.

Division of Cardiology, University of Arizona, Phoenix, Arizona.

Background: Increased afterload and reduced left ventricular (LV) performance are sequela of mitral valve repair. However, hemodynamic left atrial and ventricular parameters that can predict outcome following mitral valve repair remain elusive.

Methods: One hundred and two consecutive patients undergoing MitraClip procedure from 2014 to 2017 at Banner University Medical Center were enrolled in this study. Read More

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http://doi.wiley.com/10.1002/ccd.27804
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http://dx.doi.org/10.1002/ccd.27804DOI Listing
January 2019
4 Reads
2.110 Impact Factor

Giant left atrium with left lung damage: a case report.

J Int Med Res 2018 Nov 20;46(11):4821-4824. Epub 2018 Sep 20.

2 Department of Radiology, The Fourth Affiliated Hospital, Zhejiang University School of Medicine, Yiwu, China.

Giant left atrium is most commonly associated with rheumatic mitral valve disease, causing a series of cardiac and extracardiac complications. Cardiac complications are often reported, such as atrial fibrillation, decreased cardiac output, and atrial thrombus formation. Extracardiac complications are rarely described in the literature. Read More

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http://dx.doi.org/10.1177/0300060518799268DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6259367PMC
November 2018
8 Reads

Comparison of Early and Long-Term Outcomes After Transcatheter Aortic Valve Implantation in Patients with New York Heart Association Functional Class IV to those in Class III and Less.

Am J Cardiol 2018 Nov 21;122(10):1718-1726. Epub 2018 Aug 21.

Catheterization Laboratory, Cardiothoracic Department, Spedali Civili Brescia, Brescia, Italy.

Our aim was to investigate the impact of a baseline New York Heart Association (NYHA) class IV on clinical outcomes of a large real-world population who underwent transcatheter aortic valve implantation (TAVI). The primary end points were all-cause mortality, cardiovascular mortality, and re-hospitalization, evaluated at the longest available follow-up and by means of a 3-month landmark analysis. The secondary end points were: change in NYHA class, left ventricular ejection fraction, pulmonary pressure and mitral regurgitation. Read More

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http://dx.doi.org/10.1016/j.amjcard.2018.08.006DOI Listing
November 2018
3 Reads

Noninvasive determination of the pulmonary artery input impedance.

Med Hypotheses 2018 Nov 9;120:7-13. Epub 2018 Aug 9.

Faculty of Mechanical Engineering and Naval Architecture, University of Zagreb, Ivana Lučića 5, 10000 Zagreb, Croatia.

A reliable noninvasive method for the estimation of pulmonary function in healthy and diseased subjects should be of great importance in the prognosis, diagnosis, and treatment of pulmonary hypertension. Here we propose such a method, which is based on the parameter identification of the five-element Windkessel model of pulmonary circulation. The method requires the following input variables: the heart rate, the stroke volume, the Doppler echocardiographic measurements of the tricuspid regurgitation and the pulmonary valve velocity profiles, and estimations of the right atrium and the pulmonary vein pressure. Read More

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http://dx.doi.org/10.1016/j.mehy.2018.08.007DOI Listing
November 2018
9 Reads

The Edwards SAPIEN Valve in the Pulmonic Position: The Not-So-New Kid on the Block.

Authors:
Evan M Zahn

JACC Cardiovasc Interv 2018 Oct 12;11(19):1917-1919. Epub 2018 Sep 12.

Smidt Heart Institute and Department of Pediatrics, Cedars Sinai Medical Center, Los Angeles, California. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S19368798183136
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http://dx.doi.org/10.1016/j.jcin.2018.06.029DOI Listing
October 2018
3 Reads

Edwards SAPIEN Transcatheter Pulmonary Valve Implantation: Results From a French Registry.

JACC Cardiovasc Interv 2018 Oct 12;11(19):1909-1916. Epub 2018 Sep 12.

Centre Hospitalier Universitaire de Nantes, Institut du Thorax, Fédération des Cardiopathies Congénitales, Service de Cardiologie, Nantes, France.

Objectives: The aim of this study was to describe and analyze data from patients treated in France with the Edwards SAPIEN transcatheter heart valve (Edwards Lifesciences LLC, Irvine, California) in the pulmonary position.

Background: The Edwards SAPIEN valve has recently been introduced for percutaneous pulmonary valve implantation (PPVI).

Methods: From April 2011 to May 2017, 71 patients undergoing PPVI were consecutively included. Read More

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http://dx.doi.org/10.1016/j.jcin.2018.05.050DOI Listing
October 2018
2 Reads

The Modified Ross Procedure with Prosthetic Graft Wrap Does Not Prevent Autograft Failure.

J Heart Valve Dis 2017 11;26(6):735-737

Duke University Medical Center, Durham, NC, USA, Electronic correspondence:

The modified Ross procedure, which involves replacement of the aortic valve with a pulmonary autograft root supported within a Dacron tube graft, was developed with the goal of preventing late autograft dilatation and associated aortic insufficiency. The case is reported of an adult patient who had a bicuspid aortic valve (BAV), underwent a modified Ross procedure, and developed severe aortic insufficiency within one year and subsequently required reoperation for aortic valve replacement. While advances have been made to increase the success of the Ross procedure via modifications to prevent aortic root dilatation, no modifications have yet been devised to improve the ability of the pulmonary valve to withstand systemic aortic pressures. Read More

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November 2017
6 Reads

Is there still a role for balloon aortic valvuloplasty in the TAVR era?

Authors:
Harold L Lazar

J Card Surg 2018 10 5;33(10):607-608. Epub 2018 Sep 5.

Division of Cardiac Surgery, The Boston University School of Medicine, Boston, Massachusetts.

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http://dx.doi.org/10.1111/jocs.13807DOI Listing
October 2018
1 Read

Transcatheter closure of ventricular septal defect in aortic valve prolapse and aortic regurgitation.

Indian Heart J 2018 Jul - Aug;70(4):528-532. Epub 2017 Nov 27.

Department of Pediatric Cardiology, Apollo Children's Hospital, Chennai, India.

Objective: To report intermediate follow-up result of transcatheter closure of ventricular septal defect (VSD) in presence of aortic valve prolapse (AVP) with or without aortic regurgitation (AR).

Method: This is a retrospective review of 19 patients with VSD with AVP with AR who underwent transcatheter closure in between September 2011-July 2014. Mean age was 8 years (1-16 years, standard deviation [SD] 4. Read More

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http://dx.doi.org/10.1016/j.ihj.2017.11.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117845PMC
October 2018
3 Reads

A child with fever, cough and Lancisi's sign.

Pan Afr Med J 2018;30:14. Epub 2018 May 8.

Paris Fire Department, Paris, France.

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http://dx.doi.org/10.11604/pamj.2018.30.14.15397DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6110539PMC
October 2018
1 Read

Cardiovascular Safety of Lorcaserin in Overweight or Obese Patients.

N Engl J Med 2018 09 26;379(12):1107-1117. Epub 2018 Aug 26.

From the Thrombolysis in Myocardial Infarction (TIMI) Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital, Boston (E.A.B., S.D.W., J.K., K.I., A.Q., M.P.B., C.T.R., M.S.S., B.M.S.); the Cardiovascular Division, University of Texas Southwestern Medical Center, Dallas (D.K.M.); the Section of Endocrinology, Yale School of Medicine, New Haven, CT (S.E.I.); the Department of Medicine, University of Minnesota, Minneapolis (C.L.F.); the Partners Clinical Research Centre, Nassau, Bahamas (C.B.); the Department of Cardiology, Postgraduate Medical School, Grochowski Hospital, Warsaw, Poland (A.B.); Cardiolink Clinical Trials, Monterrey, Mexico (A.G.-C.); McMaster University, Brampton, ON (M.G.), and the Division of Endocrinology and Metabolism, St. Michael's Hospital, University of Toronto, Toronto (L.A.L.) - both in Canada; MedStar Health Research Institute, Hyattsville, MD (N.J.W.); the Cardiology Department, Auckland City Hospital, Auckland, New Zealand (H.D.W.); Eisai, Woodcliff Lake, NJ (T.P., B.F., W.M., C.P., S.D.); National Health and Medical Research Council Clinical Trials Centre, University of Sydney, Sydney (A.C.K.); and the Translational Research Institute for Metabolism and Diabetes, Florida Hospital and the Sanford-Burnham Institute, Winter Park (S.R.S.).

Background: Lorcaserin, a selective serotonin 2C receptor agonist that modulates appetite, has proven efficacy for weight management in overweight or obese patients. The cardiovascular safety and efficacy of lorcaserin are undefined.

Methods: We randomly assigned 12,000 overweight or obese patients with atherosclerotic cardiovascular disease or multiple cardiovascular risk factors to receive either lorcaserin (10 mg twice daily) or placebo. Read More

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http://dx.doi.org/10.1056/NEJMoa1808721DOI Listing
September 2018
10 Reads

Renin-angiotensin-aldosterone system blockade in patients with repaired tetralogy of Fallot: When and how.

Int J Cardiol 2018 12 18;272:88-89. Epub 2018 Aug 18.

Department of Pediatrics, National Taiwan University Hospital, National Taiwan University, Taiwan.

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http://dx.doi.org/10.1016/j.ijcard.2018.08.050DOI Listing
December 2018
2 Reads

Impact of maternal pulmonary insufficiency on fetal growth in pregnancy.

J Matern Fetal Neonatal Med 2018 Sep 19:1-7. Epub 2018 Sep 19.

a Maternal-Fetal Medicine Division, Obstetrics & Gynecology Department , Sainte-Justine University Hospital , Montreal , Canada.

Rationale: It is known that fetal growth is usually proportional to left-sided cardiac output (CO), which parallels the right-sided CO and that congenital right-sided lesions are usually associated with better perinatal outcomes than left-sided lesions.

Objective: Our objective was to document whether newborns from mothers with severe residual pulmonary valve insufficiency (PI) after surgical tetralogy of Fallot (TOF) or pulmonary valve stenosis (PS) correction have lower birth weight (BW) than newborns from mothers with absent, mild, or moderate PI.

Methods: This is a retrospective cohort study of women affected with repaired TOF and corrected PS with varied severity of residual PI. Read More

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http://dx.doi.org/10.1080/14767058.2018.1514492DOI Listing
September 2018
3 Reads

Optimal timing for pulmonary valve replacement in asymptomatic patients after tetralogy of Fallot repair using cardiac magnetic resonance imaging.

Kardiol Pol 2018 ;76(8):1271-1273

Department of Paediatric Cardiology, Faculty of Medicine, Comenius University, Bratislava, Limbova 1, 83101 Bratislava, Slovakia; Paediatric Cardiology, National Institute of Cardiovascular Diseases, Children`s Cardiac Centre, Limbova 1, 83101 Bratislava, Slovakia.

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http://dx.doi.org/10.5603/KP.2018.0164DOI Listing
December 2018
3 Reads

Impact of Pulmonary Valve Regurgitation on Pressure Difference of Pulmonary Valve Stenosis in Patients with Tetralogy of Fallot After Repair.

Pediatr Cardiol 2018 Dec 13;39(8):1663-1668. Epub 2018 Aug 13.

Department of Clinical Engineering, Chiba Children's Hospital, Chiba, 266-0007, Japan.

Pressure difference (PD) is an important parameter in evaluating the degree of stenotic lesion. However, PD is influenced by the blood flow volume passing through the stenosis. In patients with tetralogy of Fallot (TOF), pulmonary valve regurgitation (PR) and pulmonary valve stenosis (vPS) are common post-operative complications. Read More

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http://dx.doi.org/10.1007/s00246-018-1947-zDOI Listing
December 2018
1 Read

Late results of the Ross procedure.

J Thorac Cardiovasc Surg 2019 Jan 18;157(1):201-208. Epub 2018 Jul 18.

Division of Cardiovascular Surgery, Peter Munk Cardiac Centre, Toronto General Hospital and the University of Toronto, Toronto, Ontario, Canada.

Objective: The study objective was to examine the long-term results of the Ross procedure in a cohort of patients followed prospectively for more than 2 decades.

Methods: From 1990 to 2004, 212 consecutive patients with a median age (interquartile range) of 34 years (28-41) underwent the Ross procedure; 82% had congenital aortic valve disease. The technique of aortic root replacement was used in one half of the patients. Read More

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http://dx.doi.org/10.1016/j.jtcvs.2018.06.037DOI Listing
January 2019
2 Reads
4.170 Impact Factor

[The Old-Age Heart].

Praxis (Bern 1994) 2018 Aug;107(16):894-901

1 HerzGefässZentrum Zürich, Klinik Im Park, Zürich.

The Old-Age Heart Abstract. Knowledge of cardiovascular changes in old age and their therapeutic options is important. Old age can lead to hypertrophy of the left ventricle, diastolic dysfunction, heart valve changes and pulmonary hypertension. Read More

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http://dx.doi.org/10.1024/1661-8157/a003039DOI Listing
August 2018
2 Reads

Exercise cardiac magnetic resonance imaging with pulmonary artery catheter monitoring in carcinoid heart disease: a shift towards early intervention?

ESC Heart Fail 2018 10 6;5(5):953-955. Epub 2018 Aug 6.

Division of Cardiology, University Hospital Leuven, Herestraat 49, 3000, Leuven, Belgium.

Neuroendocrine tumours are a rare malignancy, which can be complicated by a carcinoid syndrome and, in more rare cases, also valve destruction. The correct timing for surgical repair remains unknown. We report the first-in-men exercise cardiac magnetic resonance imaging with pulmonary artery catheter measurements in order to better understand the haemodynamic impact of isolated tricuspid valve insufficiency in a low symptomatic patient. Read More

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http://dx.doi.org/10.1002/ehf2.12328DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6165946PMC
October 2018
2 Reads

Renal dysfunction is associated with higher central venous pressures in patients with Fontan circulation.

Congenit Heart Dis 2018 Jul 5;13(4):602-607. Epub 2018 Aug 5.

Department of Pediatrics, Section of Cardiology, Baylor College of Medicine/Texas Children's Hospital, Houston, Texas.

Purpose: Elevated central venous pressure (CVP) has deleterious effects on several organ systems in patients with Fontan circulation. However, the relationship between CVP and estimated glomerular filtration rate (eGFR) has not been assessed in patients with Fontan circulation.

Methods: Patients with Fontan circulation whose hemodynamics were assessed by catheterization between 1987 and 2015 and had a serum creatinine measured within 72 hours prior to the procedure were included for analysis. Read More

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http://dx.doi.org/10.1111/chd.12617DOI Listing

Safety and Feasibility of Melody Transcatheter Pulmonary Valve Replacement in the Native Right Ventricular Outflow Tract: A Multicenter Pediatric Heart Network Scholar Study.

JACC Cardiovasc Interv 2018 Aug 1;11(16):1642-1650. Epub 2018 Aug 1.

Division of Cardiology, Department of Pediatrics, University of Utah, Salt Lake City, Utah.

Objectives: This study sought to determine the safety and feasibility of transcatheter pulmonary valve replacement (TPVR) using the Melody valve in native (nonconduit) right ventricular outflow tracts (nRVOT), and to identify factors associated with successful TPVR.

Background: The Melody valve is Food and Drug Administration-approved for TPVR within right ventricle-to-pulmonary artery conduits and bioprosthetic pulmonary valves. However, most patients needing pulmonary valve replacement have nRVOT and TPVR has been adapted for this indication. Read More

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http://dx.doi.org/10.1016/j.jcin.2018.05.051DOI Listing
August 2018
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Haemodynamic effects of percutaneous mitral valve edge-to-edge repair in patients with end-stage heart failure awaiting heart transplantation.

ESC Heart Fail 2018 10 30;5(5):892-901. Epub 2018 Jul 30.

Department of Internal Medicine III, Division of Cardiology, University of Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany.

Aims: Functional mitral regurgitation is complicating end-stage heart failure and potential heart transplantation by increasing pulmonary artery pressures. The aim of the present study was to investigate feasibility and haemodynamic effects of percutaneous mitral valve edge-to-edge repair using the MitraClip™ device in patients with end-stage heart failure awaiting heart transplantation.

Methods And Results: In this retrospective study, we identified nine patients suffering from end-stage heart failure listed for heart transplantation in whom moderate-severe or severe functional mitral regurgitation was recognized and treated with percutaneous mitral valve edge-to-edge repair. Read More

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http://dx.doi.org/10.1002/ehf2.12313DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6165942PMC
October 2018
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An Atypical Case of Silent Aortic Dissection in a Peritoneal Dialysis Patient: A Case Report and Review of Literature.

Am J Case Rep 2018 Jul 27;19:880-883. Epub 2018 Jul 27.

Department of Medicine, Drexel University College of Medicine, Philadelphia, PA, USA.

BACKGROUND Aortic dissection presents with acute chest or back pain and is associated with high mortality. We present a case of aortic dissection with an atypical presentation in a peritoneal dialysis patient, and the challenges met with peritoneal dialysis. CASE REPORT A 53-year-old African American male presented with progressively worsening exertional dyspnea and orthopnea for 3 days without any history of chest pain. Read More

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http://dx.doi.org/10.12659/AJCR.909966DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078011PMC
July 2018
7 Reads