Ultrasound Obstet Gynecol 2021 Jun 5. Epub 2021 Jun 5.
Fetal i+D Fetal Medicine Research Center, BCNatal - Barcelona Center for Maternal-Fetal and Neonatal Medicine (Hospital Clínic and Hospital Sant Joan de Deu),, Institut Clínic de Ginecologia, Obstetricia i Neonatologia, Institut d'Investigacions Biomèdiques August Pi i Sunyer, Universitat de Barcelona, Barcelona, Spain.
Objective: In fetuses with left-sided isolated congenital diaphragmatic hernia (LCDH), prenatal detection of severe pulmonary hypoplasia is relevant since fetal therapy can improve survival. Moderate and mild hypoplasia still carry a considerable mortality and morbidity risk, but there has been less interest in the accurate prediction of these. In this study on fetuses with moderate or mild CDH, we aimed to investigate: (1) the correlation between intra-pulmonary-artery Doppler (IPaD) findings and mortality, (2) whether adding these improves prediction of mortality based on lung size and liver herniation; and (3) whether the IPaD correlates with early neonatal morbidity. Read More