8,868 results match your criteria Pulmonary Hypertension Imaging


Right and left ventricular interaction in pulmonary hypertension: Insight from velocity vector imaging.

Echocardiography 2019 Apr 15. Epub 2019 Apr 15.

Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota.

Objective: To evaluate whether global peak systolic strain (PSS) and peak systolic strain rate (PSSR) derived from velocity vector imaging (VVI) allow early recognition of regional and global right ventricular (RV) dysfunction and the impact of this on left ventricular (LV) function in patients with pulmonary hypertension (PHT).

Background: RV function is an important determinant of prognosis in patients with heart failure, pulmonary hypertension, heart transplant, and congenital heart diseases. However, evaluation of the right ventricle is often limited by its complex geometry and inadequate visualization of RV free wall. Read More

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http://dx.doi.org/10.1111/echo.14328DOI Listing
April 2019
1 Read

Imaging of pulmonary hypertension: Pictorial essay.

Chest 2019 Apr 11. Epub 2019 Apr 11.

Pulmonary hypertension (PH) is an end result of a diverse array of complex clinical conditions, which invoke hemodynamic and pathophysiological changes in the pulmonary vasculature. Many patients' symptoms begin with dyspnea on exertion for which screening tests like chest roentgenograms and more definitive non-invasive tests like CT scans are ordered initially. It is imperative that clinicians are cognizant of subtle clues on these imaging modalities that alert them to the possibility of PH. Read More

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http://dx.doi.org/10.1016/j.chest.2019.04.003DOI Listing
April 2019
7.483 Impact Factor

Echocardiographic determination of pulmonary arterial capacitance.

Int J Cardiovasc Imaging 2019 Apr 9. Epub 2019 Apr 9.

Division of Cardiology, University of California, San Francisco, 555 Mission Bay Blvd South, Box 3120, San Francisco, CA, 94158, USA.

A growing body of evidence has demonstrated that pulmonary arterial capacitance (PAC) is the strongest hemodynamic predictor of clinical outcomes across a wide spectrum of cardiovascular disease, including pulmonary hypertension and heart failure. We hypothesized that a ratio of right ventricular stroke volume (RVOT VTI) to the associated peak arterial systolic pressure (PASP) could function as a reliable non-invasive surrogate for PAC. We performed a prospective study of patients undergoing simultaneous transthoracic echocardiography and right heart catheterization (RHC) for various clinical indications. Read More

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http://dx.doi.org/10.1007/s10554-019-01595-9DOI Listing

Pulmonary vasculitis mimicking chronic thromboembolic disease.

BMJ Case Rep 2019 Apr 8;12(4). Epub 2019 Apr 8.

Radiology, Royal United Hospitals Bath NHS Foundation Trust, Bath, UK.

A 29-year-old female patient presented with chest pain, breathlessness and syncope on the background of constitutional symptoms, oral ulceration and a rash. Multiple investigations were performed, including a CT pulmonary angiogram (CTPA) that was initially felt to show imaging features consistent with a diagnosis of chronic thromboembolic disease (CTED). The patient was referred to a tertiary pulmonary hypertension centre and the possibility of pulmonary vasculitis was raised. Read More

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http://dx.doi.org/10.1136/bcr-2018-228409DOI Listing
April 2019
1 Read

Pulmonary endarterectomy in a toddler with chronic thromboembolic pulmonary hypertension after Denver shunt.

J Thorac Cardiovasc Surg 2019 Mar 2. Epub 2019 Mar 2.

Division of Thoracic Surgery, University Health Network, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.jtcvs.2019.02.085DOI Listing

Non-invasive Multimodality Cardiovascular Imaging of the Right Heart and Pulmonary Circulation in Pulmonary Hypertension.

Front Cardiovasc Med 2019 14;6:24. Epub 2019 Mar 14.

Section of Cardiovascular Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, CT, United States.

Pulmonary hypertension (PH) is defined as resting mean pulmonary arterial pressure (mPAP) ≥25 millimeters of mercury (mmHg) via right heart (RH) catheterization (RHC), where increased afterload in the pulmonary arterial vasculature leads to alterations in RH structure and function. Mortality rates have remained high despite therapy, however non-invasive imaging holds the potential to expedite diagnosis and lead to earlier initiation of treatment, with the hope of improving prognosis. While historically the right ventricle (RV) had been considered a passive chamber with minimal role in the overall function of the heart, in recent years in the evaluation of PH and RH failure the anatomical and functional assessment of the RV has received increased attention regarding its performance and its relationship to other structures in the RH-pulmonary circulation. Read More

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http://dx.doi.org/10.3389/fcvm.2019.00024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6427926PMC
March 2019
1 Read

Prolonged Ultrasound-Assisted Catheter-Directed Low-Dose Thrombolysis for Acute Pulmonary Embolism Unresponsive to Systemic Thrombolysis.

J Invasive Cardiol 2019 Apr;31(4):E56-E57

Interventional Cardiology Unit, GVM Care & Research Maria Cecilia Hospital, Via Madonna di Genova 1, 48033 Cotignola (RA), Italy.

Our experience suggests that ultrasound-assisted thrombolysis with the EkoSonic system could be a valid bail-out strategy in cases of massive pulmonary embolism unresponsive to systemic thrombolysis and provides insight into the role of prolonged administration time in non-high bleeding risk patients with elevated thrombotic burden and initial suboptimal results. In this setting, multimodality imaging could guide patient selection and monitor treatment efficacy to individualize its duration in cases of slow hemodynamic improvement. Read More

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April 2019
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Impact of large periprocedural myocardial infarction on mortality after percutaneous coronary intervention and coronary artery bypass grafting for left main disease: an analysis from the EXCEL trial.

Eur Heart J 2019 Mar 28. Epub 2019 Mar 28.

Clinical Trials Center, Cardiovascular Research Foundation, 1700 Broadway, 9th Floor, New York, NY 10019, USA.

Aims: The prognostic implications of periprocedural myocardial infarction (PMI) after percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG) remain controversial. We examined the 3-year rates of mortality among patients with and without PMI undergoing left main coronary artery intervention randomized to PCI with everolimus-eluting stents vs. CABG in the large-scale, multicentre, prospective, randomized EXCEL trial. Read More

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https://academic.oup.com/eurheartj/advance-article/doi/10.10
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http://dx.doi.org/10.1093/eurheartj/ehz113DOI Listing
March 2019
3 Reads

Four-dimensional Flow MRI: Principles and Cardiovascular Applications.

Radiographics 2019 Mar 22:180091. Epub 2019 Mar 22.

From the Departments of Medical Imaging (A.A., N.C., G.A., S.S., V.M., M.Z.), Cardiology (P.G.), and Vascular Medicine (A.S.), Saint Joseph Hospital, 185 rue Raymond Losserand, 75014 Paris, France; and Department of Pediatric Cardiology, Necker Enfants Malades Hospital, Paris, France (D.S.).

In-plane phase-contrast (PC) imaging is now a routine component of MRI of regional blood flow in the heart and great vessels. In-plane PC MRI provides a volumetric, isotropic, time-resolved cine sequence that enables three-directional velocity encoding, a technique known as four-dimensional (4D) flow MRI. Recent advances in 4D flow MRI have shortened imaging times, while progress in big-data processing has improved dataset pre- and postprocessing, thereby increasing the feasibility of 4D flow MRI in clinical practice. Read More

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http://dx.doi.org/10.1148/rg.2019180091DOI Listing
March 2019
1 Read

Incidence and Clinical Significance of Cerebral Embolism During Atrial Fibrillation Ablation With Duty-Cycled Phased-Radiofrequency Versus Cooled-Radiofrequency: A Randomized Controlled Trial.

JACC Clin Electrophysiol 2019 Mar 26;5(3):318-326. Epub 2018 Dec 26.

Department of Cardiology, Heart Lung Center, Leiden University Medical Center, Leiden, the Netherlands. Electronic address:

Objectives: The purpose of this study was to randomly compare the incidence of asymptomatic cerebral embolism (ACE) between the second-generation pulmonary vein ablation catheter (PVAC Gold) and the irrigated Thermocool catheter.

Background: Pulmonary vein isolation (PVI) with the PVAC is associated with ACE. The PVAC Gold was designed to avoid this complication. Read More

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http://dx.doi.org/10.1016/j.jacep.2018.11.008DOI Listing
March 2019
2 Reads

Do radiologists detect chronic thromboembolic disease on computed tomography?

Acta Radiol 2019 Mar 21:284185119836232. Epub 2019 Mar 21.

1 Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden.

Background: Chronic thromboembolic pulmonary hypertension (CTEPH), a complication of acute pulmonary embolism, is a potentially curable form of pulmonary hypertension (PH). CTEPH is under-diagnosed for a number of reasons leading to delayed referral or missed diagnosis; however, the frequency of misdiagnosis of CTEPH findings on computed tomography (CT) is currently unknown.

Purpose: To evaluate the extent of misdiagnosis of CTEPH on CT. Read More

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http://dx.doi.org/10.1177/0284185119836232DOI Listing
March 2019
1 Read

Pulmonary hypertension with massive megalosplenia: A case report.

Medicine (Baltimore) 2019 Mar;98(12):e14594

Department of Cardiology.

Rationale: Pulmonary hypertension (PH) is a complicated disease which has complex causes and poor outcome. Many factors are involved in the increase of pulmonary artery pressure. It is often difficult to identify the specific cause of a particular patient. Read More

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http://dx.doi.org/10.1097/MD.0000000000014594DOI Listing
March 2019
2 Reads

The overlooked left ventricle in persistent pulmonary hypertension of the newborn.

J Matern Fetal Neonatal Med 2019 Mar 28:1-5. Epub 2019 Mar 28.

d Pediatrics Department, Faculty of Medicine , Cairo University Children Hospital, Cairo University , Cairo , Egypt.

Introduction: Persistent pulmonary hypertension of the newborn (PPHN) is a rapidly increasing condition among neonates. It represents failure of adaptation of pulmonary circulation to the extrauterine environment causing severe hypoxemia in affected newborns. Few data have weighed the relationship of ventricular dysfunction in the context of PPHN and the outcome in involved patients. Read More

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https://www.tandfonline.com/doi/full/10.1080/14767058.2019.1
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http://dx.doi.org/10.1080/14767058.2019.1598363DOI Listing
March 2019
4 Reads

Combined pulmonary fibrosis and emphysema characteristics in a Greek cohort.

ERJ Open Res 2019 Feb 18;5(1). Epub 2019 Mar 18.

Respiratory Medicine Dept, University of Thessaly, School of Medicine, Larissa, Greece.

Background: Combined pulmonary fibrosis and emphysema (CPFE) has recently received great attention, with studies suggesting that it presents a distinct clinical entity while others have challenged this hypothesis. This nationwide study aimed to describe a large cohort of Greek CPFE patients and to examine potential prognostic factors for survival.

Methods: This retrospective study included 97 patients with CPFE. Read More

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http://dx.doi.org/10.1183/23120541.00014-2018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421361PMC
February 2019
1 Read

Experimental and quantitative imaging techniques in interstitial lung disease.

Thorax 2019 Mar 18. Epub 2019 Mar 18.

Academic Unit of Academic Radiology, University of Sheffield, Sheffield, UK.

Interstitial lung diseases (ILDs) are a heterogeneous group of conditions, with a wide and complex variety of imaging features. Difficulty in monitoring, treating and exploring novel therapies for these conditions is in part due to the lack of robust, readily available biomarkers. Radiological studies are vital in the assessment and follow-up of ILD, but currently CT analysis in clinical practice is qualitative and therefore somewhat subjective. Read More

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http://dx.doi.org/10.1136/thoraxjnl-2018-211779DOI Listing
March 2019
5 Reads

Neurofibromatosis type 1: State-of-the-art review with emphasis on pulmonary involvement.

Respir Med 2019 Mar 17;149:9-15. Epub 2019 Jan 17.

Federal University of Rio de Janeiro, Rio de Janeiro, Brazil. Electronic address:

Neurofibromatosis type 1 (NF-1), also known as von Recklinghausen's disease, is an autosomal dominant dysplasia of the ectoderm and mesoderm with a variable clinical expression, but near-complete penetrance before the age of 5 years. The estimated incidence is 1 in 3000 births. NF-1 is characterized by collections of neurofibromas, café-au-lait spots, axillary and inguinal freckling, and pigmented hamartomas in the iris (Lisch nodules). Read More

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http://dx.doi.org/10.1016/j.rmed.2019.01.002DOI Listing
March 2019
1 Read

Dynamic changes of pulmonary arterial pressure in perinatal neonates with pulmonary and extrapulmonary acute lung injury/respiratory distress syndrome.

Medicine (Baltimore) 2019 Mar;98(11):e14830

Department of Neonate, Yancheng Third People's Hospital, Yancheng, China.

This study aims to explore the dynamic changes of pulmonary arterial pressure (PAP) and its clinical significance in prenatal neonates with pulmonary and extra-pulmonary acute lung injury/respiratory distress syndrome (ALI/ARDS).A prospective study was conducted in the Neonate Intensive Care Unit (NICU) between May 2015 and April 2017. A total of 78 prenatal neonates with ALI/ARDS were selected and divided into 2 groups: pulmonary group (n = 37) and extra-pulmonary group (n = 41). Read More

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http://dx.doi.org/10.1097/MD.0000000000014830DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426575PMC
March 2019
4 Reads

Imaging Risk in Multisystem Inflammatory Diseases.

JACC Cardiovasc Imaging 2019 Mar 8. Epub 2019 Mar 8.

Second Cardiology Department, Attikon Hospital, Medical School, National and Kapodistrian University of Athens, Greece.

Rheumatic diseases are immune-mediated inflammatory multisystem diseases with frequent cardiovascular manifestations including perimyocarditis, valvular disease, coronary artery disease, heart failure with or without preserved ejection fraction, pulmonary hypertension, aneurysms, and thrombosis. Echocardiography, carotid ultrasonography, cardiac computed tomography, cardiac magnetic resonance imaging, and positron emission tomography are valid diagnostic tools for the detection of the cardiovascular complications of the multisystem diseases that frequently determine prognosis. Furthermore, the findings of these methods may offer additive risk stratification in asymptomatic patients over the conventional risk scores used to assess cardiovascular risk in the primary prevention setting. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S1936878X193017
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http://dx.doi.org/10.1016/j.jcmg.2018.06.033DOI Listing
March 2019
3 Reads

Cardiac Magnetic Resonance Imaging-Based Right Ventricular Strain Analysis for Assessment of Coupling and Diastolic Function in Pulmonary Hypertension.

JACC Cardiovasc Imaging 2019 Mar 13. Epub 2019 Mar 13.

Department of Internal Medicine, Justus-Liebig-University Giessen, Universities of Giessen and Marburg Lung Center, Giessen, Germany.

Objectives: This study sought to compare cardiac magnetic resonance (CMR) imaging-derived right ventricular (RV) strain and invasively measured pressure-volume loop-derived RV contractility, stiffness, and afterload and RV-arterial coupling in pulmonary hypertension (PH).

Background: In chronic RV pressure overload, RV-arterial uncoupling is considered the driving cause of RV maladaptation and eventual RV failure. The pathophysiological and clinical value of CMR-derived RV strain relative to that of invasive pressure-volume loop-derived measurements in PH remains incompletely understood. Read More

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http://dx.doi.org/10.1016/j.jcmg.2018.12.032DOI Listing

Significant functional mitral regurgitation affects left atrial function in heart failure patients: haemodynamic correlations and prognostic implications.

Eur Heart J Cardiovasc Imaging 2019 Mar 12. Epub 2019 Mar 12.

Department of Cardiology, AORN Ospedali dei Colli-Monaldi, Naples, Italy.

Aims: Functional mitral regurgitation (FMR) is a well-known pathophysiological factor in heart failure (HF) patients, and left atrial function (LAF) is a novel determinant of clinical status and outcome in this setting. However, little is known about the pathophysiological role of FMR on LAF in HFrEF patients. Aim of this study is to explore the possible interplay between the severity of FMR and LAF in heart failure with reduce ejection fraction (HFrEF) patients and their possible consequences. Read More

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http://dx.doi.org/10.1093/ehjci/jez036DOI Listing
March 2019
2 Reads
3.669 Impact Factor

Multimodality imaging in ischaemic heart failure.

Lancet 2019 03;393(10175):1056-1070

Department of Cardiology, Leiden University Medical Center, Leiden, Netherlands.

In heart failure, extensive evaluation with modern non-invasive imaging modalities is needed to assess causes, pathophysiology, and haemodynamics, to determine prognosis and consider therapeutic options. This systematic evaluation includes a stepwise assessment of left ventricular size and function, the presence and severity of coronary artery disease, mitral regurgitation, pulmonary hypertension, right ventricular dilation and dysfunction, and tricuspid regurgitation. Based on this imaging-derived information, the need for specific therapies besides optimised medical therapy can be determined. Read More

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http://dx.doi.org/10.1016/S0140-6736(18)33207-0DOI Listing
March 2019
5 Reads

Preoperative balloon pulmonary angioplasty enabled noncardiac surgery of a patient with chronic thromboembolic pulmonary hypertension (CTEPH): A case report.

Medicine (Baltimore) 2019 Mar;98(10):e14807

Department of Anesthesiology, Faculty of Medicine, The University of Tokyo, Tokyo.

Rationale: Chronic thromboembolic pulmonary hypertension (CTEPH) is a disease with a poor prognosis, characterized by chronic thromboembolic obstruction of the pulmonary arteries and pulmonary hypertension. Balloon pulmonary angioplasty (BPA) is a newly emergent treatment for CTEPH, which may substitute pulmonary endarterectomy, the standard but more invasive treatment for CTEPH. Here, we report the case of a CTEPH patient who underwent 2 noncardiac surgeries without complications after preoperative intervention of BPA. Read More

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http://Insights.ovid.com/crossref?an=00005792-201903080-0006
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http://dx.doi.org/10.1097/MD.0000000000014807DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417548PMC
March 2019
2 Reads

Right Ventricular Size and Function in Chronic Heart Failure: Not to Be Forgotten.

Heart Fail Clin 2019 Apr 10;15(2):205-217. Epub 2019 Feb 10.

Cardiology Division, A. Cardarelli Hospital, Naples, Italy. Electronic address:

A comprehensive multi-imaging evaluation of the right heart structure, function, and pressures represents an essential step in the diagnostic and prognostic algorithm of patients with heart failure. Furthermore, it provides important information for detecting early signs of right ventricular unfavorable remodeling, and consequently, guiding appropriate therapeutic interventions. Read More

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http://dx.doi.org/10.1016/j.hfc.2018.12.015DOI Listing

Inhibition of RhoA/ROCK signaling pathway ameliorates hypoxic pulmonary hypertension via HIF-1α-dependent functional TRPC channels.

Toxicol Appl Pharmacol 2019 Apr 1;369:60-72. Epub 2019 Mar 1.

Key Laboratory of Gastrointestinal Pharmacology of Chinese Materia Medica of the State Administration of Traditional Chinese Medicine, Department of Pharmacology, School of Pharmacy, Fourth Military Medical University, Xi'an, China. Electronic address:

Hypoxic pulmonary vasoconstriction (HPV) can be modulated by Rho/Rho kinase signaling, which can alter HPV vascular function via regulating myosin light chain phosphorylation, in a manner generally believed to be Ca-independent. We hypothesized that the RhoA/ROCK signaling pathway also can regulate HPV vascular function via a Ca-dependent mechanism, signaling through the functional transient receptor potential canonical (TRPC) channels. In this study, male BALB/c mice were exposed to normoxic or 10% oxygen (hypoxic) conditions for six weeks, after which systolic pressure and right ventricular hypertrophy were assessed. Read More

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http://dx.doi.org/10.1016/j.taap.2019.02.017DOI Listing
April 2019
2 Reads

Pulmonary capillary hemangiomatosis: An unusual cause of primary pulmonary hypertension in a child with characteristic computed tomography imaging features.

Lung India 2019 Mar-Apr;36(2):157-159

Department of Pulmonary Medicine, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.

Pulmonary capillary hemangiomatosis (PCH) is a rare cause of primary pulmonary hypertension (PPH) diagnosed in children and young adults with a nonspecific clinical presentation of dyspnea, cough, chest pain, and fatigue. It is characterized by extensive proliferation of pulmonary capillaries within alveolar septa. The imaging features include diffuse centrilobular ground-glass opacities with features of pulmonary hypertension. Read More

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http://dx.doi.org/10.4103/lungindia.lungindia_122_18DOI Listing
March 2019
1 Read

Echocardiography in Pulmonary Arterial Hypertension.

Curr Cardiol Rep 2019 Mar 4;21(4):22. Epub 2019 Mar 4.

Division of Cardiology, A. Cardarelli Hospital, Via A. Cardarelli, 9, 80131, Naples, Italy.

Purpose Of Review: Pulmonary arterial hypertension (PAH) is a devastating disease which can result in right heart (RH) failure and death. Herein, we discuss the current clinical applications of echocardiography in PAH.

Recent Findings: Advanced echocardiographic techniques (strain, strain rate, 2D-speckle tracking strain, and three-dimensional echocardiography) may reveal in the near future additional important insights into RH structure and function. Read More

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http://link.springer.com/10.1007/s11886-019-1109-9
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http://dx.doi.org/10.1007/s11886-019-1109-9DOI Listing
March 2019
2 Reads

Myxomatous mitral valve disease in the miniature poodle: A retrospective study.

Vet J 2019 Feb 19;244:94-97. Epub 2018 Dec 19.

Department of Veterinary Clinical Sciences, North Carolina State University, Raleigh, NC, 27607, USA.

Myxomatous mitral valve disease (MMVD) is the most common cardiovascular disease in the dog. The natural history of the disease is wide ranging and includes patients without clinical signs as well as those with significant clinical consequences from cardiac arrhythmias, pulmonary hypertension and/or congestive heart failure. The factors that determine which dogs remain asymptomatic and which develop clinical disease are not known. Read More

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http://dx.doi.org/10.1016/j.tvjl.2018.12.019DOI Listing
February 2019
1 Read

The feasibility and clinical implication of tricuspid regurgitant velocity and pulmonary flow acceleration time evaluation for pulmonary pressure assessment during exercise stress echocardiography.

Eur Heart J Cardiovasc Imaging 2019 Mar 1. Epub 2019 Mar 1.

Department of Cardiology, Medical University of Lodz, Bieganski Hospital, Ul. Kniaziewicza 1/5, 91-347 Lodz, Poland.

Aims: Echocardiography can estimate pulmonary arterial pressure (PAP) from tricuspid regurgitation velocity (TRV) or acceleration time (ACT) of pulmonary flow. We assessed the feasibility of TRV and ACT measurements during exercise stress echocardiography (ESE) and their correlation in all stages of ESE.

Methods And Results: We performed ESE in 102 subjects [mean age 49 ± 17 years, 50 females, 39 healthy, 30 with cardiovascular risk factors, and 33 with pulmonary hypertension (PH)] referred for the assessment of exercise tolerance and ischaemia exclusion. Read More

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http://dx.doi.org/10.1093/ehjci/jez029DOI Listing
March 2019
1 Read

Transthoracic Pulmonary Artery Denervation for Pulmonary Arterial Hypertension.

Arterioscler Thromb Vasc Biol 2019 Apr;39(4):704-718

From the State Key Laboratory of Cardiovascular Diseases and Center for Pediatric Cardiac Surgery, Fuwai Hospital, National Center for Cardiovascular Diseases (Y.H., Y.-W.L., X.-L.Z., J.L., L.X., J.M., P.-H.W., H.Z.), Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing.

Objective- Pulmonary arterial hypertension is characterized by progressive pulmonary vascular remodeling and persistently elevated mean pulmonary artery pressures and pulmonary vascular resistance. We aimed to investigate whether transthoracic pulmonary artery denervation (TPADN) attenuated pulmonary artery (PA) remodeling, improved right ventricular (RV) function, and affected underlying mechanisms. We also explored the distributions of sympathetic nerves (SNs) around human PAs for clinical translation. Read More

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http://dx.doi.org/10.1161/ATVBAHA.118.311992DOI Listing
April 2019
2 Reads
6.000 Impact Factor

Normal ventilation/perfusion lung scan in patients with extensive chronic thromboembolism pulmonary hypertension: A case report.

Radiol Case Rep 2019 Apr 16;14(4):510-513. Epub 2019 Feb 16.

Department of Radiology, Nuclear Medicine and PET Imaging & Cardiovascular Imaging, King Faisal Specialist Hospital & Research Center, Riyadh, Saudi Arabia.

Chronic thromboembolism pulmonary hypertension (CTEPH) is a common cause of severe pulmonary hypertension, resulting in significant morbidity and mortality. In patients with unexplained pulmonary hypertension, a ventilation-perfusion (VQ) scan should be considered the initial diagnostic test of choice. VQ scans are widely available with excellent sensitivity, specificity, and diagnostic accuracy. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S19300433183060
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http://dx.doi.org/10.1016/j.radcr.2019.01.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378339PMC
April 2019
6 Reads

Perfusion Imaging Distinguishes Exercise Pulmonary Arterial Hypertension at Rest.

Am J Respir Crit Care Med 2019 Feb 27. Epub 2019 Feb 27.

Massachusetts General Hospital and Harvard Medical School, Pulmonary and Critical Care Unit, Boston, Massachusetts, United States.

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http://dx.doi.org/10.1164/rccm.201810-1899LEDOI Listing
February 2019
1 Read

Sclerosing Mediastinitis Causing Unilateral Pulmonary Edema Due to Left Atrial and Pulmonary Venous Compression. A Case Report and Literature Review.

Braz J Cardiovasc Surg 2019 Jan-Feb;34(1):85-92

Department of Cardiothoracic Surgery, University Hospital of Patras, Patras, Greece.

Sclerosing mediastinitis (SM), previously named chronic fibrosing mediastinitis, is an inflammatory process that in its end-stage results to sclerosis around the mediastinal structures. SM is quite rare and has been correlated with inflammatory and autoimmune diseases, as well as malignancy. SM may either present in a mild form, with minor symptoms and a benign course or in a more aggressive form with severe pulmonary hypertension and subsequent higher morbidity and mortality. Read More

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http://dx.doi.org/10.21470/1678-9741-2018-0067DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385839PMC
March 2019
1 Read
0.632 Impact Factor

Normal values of aortic dimensions assessed by multidetector computed tomography in the Copenhagen General Population Study.

Eur Heart J Cardiovasc Imaging 2019 Feb 26. Epub 2019 Feb 26.

Department of Cardiology, Rigshospitalet, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 9, Copenhagen, Denmark.

Aims: Accurate assessment of aortic dimensions can be achieved using contrast-enhanced computed tomography. The aim of this study was to define normal values and determinants of aortic dimensions throughout multiple key anatomical landmarks of the aorta in healthy individuals from the Copenhagen General Population Study.

Methods And Results: The study group consisted of 902 healthy subjects selected from 3000 adults undergoing cardiovascular thoracic and abdominal computed tomography-angiography (CTA), where systematic measurements of aortic dimensions were performed retrospectively. Read More

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http://dx.doi.org/10.1093/ehjci/jez012DOI Listing
February 2019
3 Reads

Unilateral absence of the pulmonary veins: an unusual diagnosis with characteristic imaging findings.

Clin Imaging 2019 Jan 30;55:107-111. Epub 2019 Jan 30.

Department of Radiology, Helen DeVos Children's Hospital and Spectrum Health, Advanced Radiology Services, Grand Rapids, MI, United States of America; New York Medical College, Valhalla, NY, United States of America.

Background: Congenital unilateral absence of the pulmonary vein (UCAPV) is a rare entity with characteristic clinical and imaging findings. Despite its congenital nature, the radiographic findings and symptoms of UCAPV may not be recognized at birth and patients may present in childhood or early adulthood with findings that may mimic other diagnoses.

Methods: The evolution of imaging findings in UCAPV is presented through two cases, one of which demonstrates the progression of findings over several years. Read More

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http://dx.doi.org/10.1016/j.clinimag.2019.01.022DOI Listing
January 2019
3 Reads

Noncontrast Chest Computed Tomographic Imaging of Obesity and the Metabolic Syndrome: Part I Cardiovascular Findings.

J Thorac Imaging 2019 Mar;34(2):116-125

Department of Radiology, University of Wisconsin-Madison, Madison, WI.

There are physiological consequences of overeating that can lead to increased morbidity and mortality. The purpose of this review article is to acquaint the reader with the current state of the art in the non-cardiac-gated, noncontrast chest computed tomographic (NCCT) imaging biomarkers of the metabolic syndrome and their prognostic significance found in the lower neck and chest. NCCT imaging biomarkers associated with metabolic syndrome in the chest include premature coronary artery calcification, acceleration of large vessel arterial and valvular calcifications associated with atherosclerosis, and pulmonary arterial enlargement from pulmonary hypertension associated with sleep apnea. Read More

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http://dx.doi.org/10.1097/RTI.0000000000000391DOI Listing
March 2019
12 Reads

A unique case of ectopic Cushing's syndrome from a thymic neuroendocrine carcinoma.

Endocrinol Diabetes Metab Case Rep 2019 Feb 22;2019. Epub 2019 Feb 22.

Departments of Endocrinology, Diabetes & Metabolism, Cleveland Clinic, Cleveland, Ohio, USA.

Ectopic adrenocorticotropic hormone (ACTH) production leading to ectopic ACTH syndrome accounts for a small proportion of all Cushing's syndrome (CS) cases. Thymic neuroendocrine tumors are rare neoplasms that may secrete ACTH leading to rapid development of hypercortisolism causing electrolyte and metabolic abnormalities, uncontrolled hypertension and an increased risk for opportunistic infections. We present a unique case of a patient who presented with a mediastinal mass, revealed to be an ACTH-secreting thymic neuroendocrine tumor (NET) causing ectopic CS. Read More

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http://dx.doi.org/10.1530/EDM-19-0002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391898PMC
February 2019
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Noncontrast Chest Computed Tomographic Imaging of Obesity and the Metabolic Syndrome: Part I Cardiovascular Findings.

J Thorac Imaging 2019 Feb 15. Epub 2019 Feb 15.

Department of Radiology, University of Wisconsin-Madison, Madison, WI.

There are physiological consequences of overeating that can lead to increased morbidity and mortality. The purpose of this review article is to acquaint the reader with the current state of the art in the non-cardiac-gated, noncontrast chest computed tomographic (NCCT) imaging biomarkers of the metabolic syndrome and their prognostic significance found in the lower neck and chest. NCCT imaging biomarkers associated with metabolic syndrome in the chest include premature coronary artery calcification, acceleration of large vessel arterial and valvular calcifications associated with atherosclerosis, and pulmonary arterial enlargement from pulmonary hypertension associated with sleep apnea. Read More

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http://Insights.ovid.com/crossref?an=00005382-201903000-0000
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http://dx.doi.org/10.1097/RTI.0000000000000391DOI Listing
February 2019
5 Reads

Deep learning cardiac motion analysis for human survival prediction.

Nat Mach Intell 2019 Feb;1:95-104

MRC London Institute of Medical Sciences, Imperial College London,UK.

Motion analysis is used in computer vision to understand the behaviour of moving objects in sequences of images. Optimising the interpretation of dynamic biological systems requires accurate and precise motion tracking as well as efficient representations of high-dimensional motion trajectories so that these can be used for prediction tasks. Here we use image sequences of the heart, acquired using cardiac magnetic resonance imaging, to create time-resolved three-dimensional segmentations using a fully convolutional network trained on anatomical shape priors. Read More

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http://dx.doi.org/10.1038/s42256-019-0019-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382062PMC
February 2019

Surgical Outcomes of Biventricular Repair for Hypoplastic Left Ventricle With Congenital Mitral Valve Stenosis.

World J Pediatr Congenit Heart Surg 2019 01;10(1):11-17

1 Department of Pediatric Cardiovascular Surgery, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan.

Objective: Surgical outcomes of biventricular repair for hearts with hypoplastic left ventricle with congenital mitral valve stenosis are described. Serial changes of left ventricular geometry and clinical features after biventricular repair were reviewed.

Methods: Eight patients with hypoplastic left ventricle and congenital mitral valve stenosis who underwent first surgical intervention for biventricular circulation in neonatal or infantile period between 2001 and 2014 comprise the study population. Read More

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http://dx.doi.org/10.1177/2150135118808748DOI Listing
January 2019
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Descending Aortic Translocation and Right Pulmonary Artery Reimplantation for Midline Descending Aorta and Crossed Pulmonary Arteries in an Infant.

World J Pediatr Congenit Heart Surg 2019 01;10(1):111-115

1 Division of Cardiovascular-Thoracic Surgery, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, USA.

Left mainstem bronchial compression by a midline descending thoracic aorta is a rare anatomic variant. Translocation of the descending thoracic aorta to the ascending aorta has recently been described to treat this condition. We performed an aortic translocation and right pulmonary artery reimplantation in a 4-month-old infant with severe pulmonary hypertension secondary to right pulmonary artery stenosis and left bronchial compression by a midline descending thoracic aorta. Read More

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http://dx.doi.org/10.1177/2150135118815027DOI Listing
January 2019
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[Analysis of risk factors of pulmonary infection in patients over 60 years of age after radical resection for gastric cancer].

Zhonghua Wei Chang Wai Ke Za Zhi 2019 Feb;22(2):164-171

Department IV of Gastrointestinal Cancer Center, Key laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Peking University Cancer Hospital and Institute, Beijing 100142,China, Email:

Objective: To investigate the risk factors of postoperative pulmonary infection (PPI) in patients over 60 years of age with gastric cancer after radical gastrectomy.

Methods: Clinicopathological data of 373 patients over 60 years of age who underwent radical gastrectomy at Department IV of Gastrointestinal Cancer Center, Peking University Cancer Hospital, from April 2009 to December 2016 were retrospectively collected in this case-control study. The clinicopathological characteristics of patients with postoperative pulmonary infection (including postoperative atelectasis) and those without pulmonary infection were compared. Read More

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February 2019
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Atrial Septal Defect of the Ostium Secundum Type in A 101-Year-Old Patient.

Int Heart J 2019 Mar 22;60(2):489-491. Epub 2019 Feb 22.

Department of Cardiology, Juntendo University.

The patient was a 101-year-old woman whose chief complaints were difficulty of breathing and high fever. The history of the present illness included paroxysmal atrial flutter which was untreated, but she had not developed heart failure.At admission, auscultation of the chest revealed moist rales and systolic murmur but did not clearly show the presence of fixed splitting of S2. Read More

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http://dx.doi.org/10.1536/ihj.18-354DOI Listing

Total anomalous pulmonary venous connection in a mature dog.

J Vet Cardiol 2019 Feb 6;21:10-17. Epub 2018 Dec 6.

Royal (Dick) School of Veterinary Studies, University of Edinburgh, Roslin, Midlothian, EH25 9RG, UK.

A 2-year 10-month, male neutered, crossbreed dog presented for evaluation of cyanosis and exercise intolerance. Doppler echocardiography revealed severe dilation of the right atrium and right ventricle with moderate pulmonary hypertension. Right-to-left shunting across a large ostium secundum atrial septal defect was confirmed by contrast echocardiography. Read More

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http://dx.doi.org/10.1016/j.jvc.2018.11.003DOI Listing
February 2019

Clinical usefulness of right ventricular 3D area strain in the assessment of treatment effects of balloon pulmonary angioplasty in chronic thromboembolic pulmonary hypertension: comparison with 2D feature-tracking MRI.

Eur Radiol 2019 Feb 21. Epub 2019 Feb 21.

Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku Fukuoka-shi, Fukuoka, Japan.

Objectives: To evaluate the usefulness of right ventricular (RV) area strain analysis via cardiac MRI (CMRI) as a tool for assessing the treatment effects of balloon pulmonary angioplasty (BPA) in inoperable chronic thromboembolic pulmonary hypertension (CTEPH), RV area strain was compared to two-dimensional (2D) strain with feature-tracking MRI (FTMRI) before and after BPA.

Methods: We retrospectively analyzed 21 CTEPH patients who underwent BPA. End-systolic global area strain (GAS), longitudinal strain (LS), circumferential strain (CS), and radial strain (RS) were measured before and after BPA. Read More

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http://dx.doi.org/10.1007/s00330-019-6008-3DOI Listing
February 2019
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Augmented reality and three-dimensional printing in percutaneous interventions on pulmonary arteries.

Quant Imaging Med Surg 2019 Jan;9(1):23-29

Department of Pulmonary Circulation, Thromboembolic Diseases and Cardiology, European Health Center, Otwock, Poland.

Background: Percutaneous pulmonary interventions require extensive and accurate navigation planning and guidance, especially in regard to the three-dimensional (3D) relationships between anatomical structures. In this study, we are demonstrating the feasibility of novel visualization techniques: 3D printing (3DP) and augmented reality (AR) in planning transcatheter pulmonary interventions.

Methods: Two patients were qualified for balloon pulmonary angioplasty (BPA) for treatment of chronic thromboembolic pulmonary hypertension (CTEPH) and stent implantation for pulmonary artery stenosis, respectively. Read More

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http://qims.amegroups.com/article/view/21630/22458
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http://dx.doi.org/10.21037/qims.2018.09.08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351817PMC
January 2019
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Reversed Pulsus Paradoxus in Right Ventricular Failure.

Methodist Debakey Cardiovasc J 2018 Oct-Dec;14(4):298-300

MCGOVERN MEDICAL SCHOOL, UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON, HOUSTON, TEXAS.

Reversed pulsus paradoxus was first described in 1973 as a rise in peak systolic pressure on inspiration in patients with idiopathic hypertrophic subaortic stenosis or isorhythmic ventricular rhythm and in patients with left ventricular systolic dysfunction on positive pressure ventilation. Positive pressure ventilation, for example, may impel blood from the pulmonary capillaries and venules into the left atrium. This may increase left ventricular preload and accelerate ventricular emptying, which in turn may cause the systolic arterial pressure to rise during inspiration. Read More

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http://dx.doi.org/10.14797/mdcj-14-4-298DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369612PMC
April 2019
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Prenatal prediction of survival in congenital diaphragmatic hernia: An audit of postnatal outcomes.

J Pediatr Surg 2019 Jan 31. Epub 2019 Jan 31.

Division of Pediatric General and Thoracic Surgery, Montreal Children's Hospital, McGill University Health Centre, Montreal, QC, Canada. Electronic address:

Purpose: Effective antenatal counseling in congenital diaphragmatic hernia (CDH) relies on proper measurement of prognostic indices. This quality initiative audited the accuracy of prenatal imaging with postnatal outcomes at two tertiary pediatric referral centers.

Methods: Prenatal lung-head ratio (LHR) and total fetal lung volume (TFLV) for CDH patients treated between 2006 and 2017 were retrieved. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00223468193005
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http://dx.doi.org/10.1016/j.jpedsurg.2019.01.021DOI Listing
January 2019
3 Reads