9,739 results match your criteria Pulmonary Hypertension Imaging


The use of magnetic resonance imaging in pulmonary hypertension: why are we still waiting?

Eur Respir Rev 2020 Jun 3;29(156). Epub 2020 Jul 3.

Dept of Pulmonary Medicine, Amsterdam Cardiovascular Sciences, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, Netherlands

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1183/16000617.0139-2020DOI Listing

Emerging role of cardiovascular magnetic resonance imaging in the management of pulmonary hypertension.

Eur Respir Rev 2020 Jun 3;29(156). Epub 2020 Jul 3.

Dept of Medicine, University of Alabama at Birmingham (UAB), Birmingham, AL, USA

Pulmonary hypertension (PH) is a clinical condition characterised by elevation of pulmonary arterial pressure (PAP) above normal range due to various aetiologies. While cardiac right-heart catheterisation (RHC) remains the gold standard and mandatory for establishing the diagnosis of PH, noninvasive imaging of the heart plays a central role in the diagnosis and management of all forms of PH. Although Doppler echocardiography (ECHO) can measure a range of haemodynamic and anatomical variables, it has limited utility for visualisation of the pulmonary artery and, oftentimes, the right ventricle. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1183/16000617.0138-2019DOI Listing

Methylephedrine-induced heart failure in a habitual user of paediatric cough syrup: a case report.

Eur Heart J Case Rep 2020 Jun 27;4(3):1-4. Epub 2020 Apr 27.

Department of Cardiology, Pulmonology, Hypertension, and Nephrology, Ehime University Graduate School of Medicine, Shitsukawa, Toon, Ehime 791-0295, Japan.

Background: For relief of cold symptoms, methylephedrine is considered to be safer than ephedrine, particularly when used at the predetermined dose. It is often present in various over-the-counter (OTC) drugs for cold, including paediatric cough syrups.

Case Summary: A 52-year-old man presented with worsening dyspnoea and anorexia for 2 weeks. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/ehjcr/ytaa095DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7319816PMC

Contemporary Outcomes of Pulmonary Valve Endocarditis: A 16-Year Single Centre Experience.

Heart Lung Circ 2020 Jun 11. Epub 2020 Jun 11.

Section of Cardiovascular Imaging, Robert and Suzanne Tomsich Department of Cardiovascular Medicine, Sydell and Arnold Miller Family Heart and Vascular Institute, Cleveland Clinic, Cleveland, OH, USA. Electronic address:

Background: Limited data exist regarding the clinical characteristics and contemporary outcomes of patients with pulmonary valve (PoV) infective endocarditis (IE).

Methods: This is a retrospective cohort study of patients with a confirmed diagnosis of IE affecting the PoV at our centre between January 2002 and October 2018. Electronic medical records were reviewed to gather the clinical and echocardiographic variables. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.hlc.2020.04.015DOI Listing

Cardiac MRI in Pulmonary Hypertension: From Magnet to Bedside.

Radiographics 2020 Jul-Aug;40(4):982-1002

From the Department of Radiology, Hospital San Juan de Dios, Hospital de la Cruz Roja, RESSALTA HT Médica, Avenida el Brillante 36, 14012 Córdoba, Spain (J.B.); Cardiothoracic Imaging Section, Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, Mo (S.B., F.R.G.); Department of Radiology, University of Colorado-Anschutz Medical Campus, Aurora, Colo (D.V.); Department of Radiology, Mayo Clinic, Rochester, Minn (E.E.W.); Cardiovascular Division, Barnes Jewish Heart and Vascular Center, St Louis, Mo (M.M.); and MRI Section, Department of Radiology, Clínica Las Nieves, SERCOSA HT Médica, Jaén, Spain (A.L.).

Pulmonary hypertension (PH) is a disease characterized by progressive rise of pulmonary artery (PA) pressure, which can lead to right ventricular (RV) failure. It is usually diagnosed late because of the nonspecificity of its symptoms. RV performance and adaptation to an increased afterload, reflecting the interaction of the PA and RV as a morphofunctional unit, constitute a critical determinant of morbidity and mortality in these patients. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1148/rg.2020190179DOI Listing

[Perspectives of using pulmonary arterial stiffness indicators to evaluate the prognosis of patients with pulmonary arterial hypertension].

Ter Arkh 2018 Jan 15;90(1):86-92. Epub 2018 Jan 15.

Almazov National Medical Research Centre.

Objective: the aim of the study was to characterize the mechanical properties of the pulmonary arterial wall (PA) in patients with pulmonary arterial hypertension (PAH) using magnetic resonance imaging (MRI) of the heart, and to determine their diagnostic and prognostic value.

Materials And Methods: 57 patients with PAH were examined. The diagnosis of PAH was verified according to the recommendations of the ERS/ESC from 2015. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.17116/terarkh201890186-92DOI Listing
January 2018

Pulmonary hypertension: The diagnostic and prognostic value of novel imaging techniques.

Hellenic J Cardiol 2020 Jun 24. Epub 2020 Jun 24.

1(st) Cardiology Department, National and Kapodistrian University of Athens University Medical School, Hippokration Hospital, Athens, Greece. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.hjc.2020.06.009DOI Listing

Pulmonary artery enlargement on routine staging F-fluodeoxyglucose positron emission tomography/CT for lung and oesophageal cancer.

Br J Radiol 2020 Jun 25:20200323. Epub 2020 Jun 25.

Department of Nuclear Medicine, Churchill Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom.

Objective: Pulmonary hypertension (PH) is an underdiagnosed condition associated with poor survival and increased post-operative mortality in lung cancer. CT-based parameters of pulmonary artery enlargement are strong predictors of PH. We used these parameters to investigate pulmonary artery enlargement in lung and oesophageal cancer. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1259/bjr.20200323DOI Listing

Identification of multilevel right-to-left shunting in a dog using nuclear scintigraphy imaging.

J Vet Cardiol 2020 May 4;30:1-6. Epub 2020 May 4.

Purdue University, College of Veterinary Medicine, Department of Veterinary Clinical Sciences, 625 Harrison Street, West Lafayette, IN 47907-2026, USA.

A 27-month-old male neutered French bulldog that was originally diagnosed with tricuspid valve dysplasia and a bidirectional shunting patent foramen ovale was evaluated for progressive polycythemia and exertional cyanosis. There was a high clinical suspicion for a right-to-left shunting patent ductus arteriosus, but given the presence of agitated saline within the left atrium, left ventricle, ascending aorta, and abdominal aorta from the previously diagnosed bidirectional shunting patent foramen ovale, a definitive diagnosis could not be made. The use of dynamic and static nuclear scintigraphy imaging using technetium-labeled macroaggregated albumin (Tc-MAA) allowed a definitive diagnosis to be made in this animal with multilevel right-to-left shunting as well as quantifying the severity of the right-to-left shunt in a minimally invasive and cost-effective manner. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jvc.2020.04.005DOI Listing

Clinical and CT findings of COVID-19: differences among three age groups.

BMC Infect Dis 2020 Jun 22;20(1):434. Epub 2020 Jun 22.

Department of Radiology, Tongde Hospital of Zhejiang Province, No. 234, Gucui Road, Hangzhou, 310012, Zhejiang Province, China.

Background: The novel coronavirus pneumonia (coronavirus disease 2019, COVID-19) has spread around the world. We aimed to recapitulate the clinical and CT imaging features of COVID-19 and their differences in three age groups.

Methods: The clinical and CT data of patients with COVID-19 (n = 307) that had been divided into three groups (Group 1: < 40 years old; Group 2: 40 ≤ age < 60 years old; Group 3: ≥ 60 years old) according to age were analyzed retrospectively. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12879-020-05154-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7306933PMC

Inverse probability of treatment analysis of open VS Endovascular repair in ruptured infrarenal aortic aneurysm - Cohort study.

Int J Surg 2020 Jun 15. Epub 2020 Jun 15.

Department of Surgery, Division of Vascular Surgery, Medical University of Vienna, Austria. Electronic address:

Background: To compare open repair (OR) with EVAR for the management of ruptured infrarenal abdominal aortic aneurysms (RAAA) in a cohort study over a time period of 15 years with inverse probability of treatment weights.

Material And Methods: From 2000/01 through 2015/12 136 patients were treated for RAAA, 98 (72.1%) underwent OR, 38 (27. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijsu.2020.05.090DOI Listing

Mapping Cardio-Pulmonary Dynamics within the Microvasculature of the Lungs using Dissolved Xe MRI.

J Appl Physiol (1985) 2020 Jun 18. Epub 2020 Jun 18.

Center for Pulmonary Imaging Research, Cincinnati Children's Hospital Medical Center, United States.

Magnetic Resonance (MR) imaging and spectroscopy using dissolved hyperpolarized (HP) Xe have expanded the ability to probe lung function regionally and non-invasively. In particular, HP Xe imaging has been used to quantify impaired gas uptake by the pulmonary tissues. Whole-lung spectroscopy has also been used to assess global cardiogenic oscillations in the MR signal intensity originating from Xe dissolved in the red blood cells of pulmonary capillaries. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1152/japplphysiol.00186.2020DOI Listing

Angiotensin Receptor-Neprilysin Inhibition Attenuates Right Ventricular Remodeling in Pulmonary Hypertension.

J Am Heart Assoc 2020 Jun 18:e015708. Epub 2020 Jun 18.

Department of BioengineeringUniversity of PittsburghPA.

BackgroundPulmonary hypertension (PH) results in increased right ventricular (RV) afterload and ventricular remodeling. Sacubitril/valsartan (sac/val) is a dual acting drug, composed of the neprilysin inhibitor sacubitril and the angiotensin receptor blocker valsartan, that has shown promising outcomes in reducing the risk of death and hospitalization for chronic systolic left ventricular heart failure. In this study, we aimed to examine if angiotensin receptor-neprilysin inhibition using sac/val attenuates RV remodeling in PH. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/JAHA.119.015708DOI Listing

NOVEL INSIGHTS ON THE PULMONARY VASCULAR CONSEQUENCES OF COVID-19.

Am J Physiol Lung Cell Mol Physiol 2020 Jun 17. Epub 2020 Jun 17.

Pulmonary Hypertension and Vascular Biology Research Group, Institut Universitaire de Cardiologie et de Pneumologie de Québec, Université Laval, Department of Medicine, Québec.

In the last few months, the number of cases of a new coronavirus-related disease (COVID-19) rose exponentially, reaching the status of a pandemic. Interestingly, early imaging studies documented that pulmonary vascular thickening was specifically associated with COVID-19 pneumonia, implying a potential tropism of the virus for the pulmonary vasculature. Moreover, SARS-CoV-2 infection is associated with inflammation, hypoxia, oxidative stress, mitochondrial dysfunction, DNA damage and lung coagulopathy promoting endothelial dysfunction and microthrombosis. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1152/ajplung.00195.2020DOI Listing
June 2020
4.080 Impact Factor

CT-derived pulmonary vascular metrics and clinical outcome in COVID-19 patients.

Quant Imaging Med Surg 2020 Jun;10(6):1325-1333

Unit of Radiology, IRCCS Policlinico San Donato, San Donato Milanese, Italy.

To assess pulmonary vascular metrics on chest CT of COVID-19 patients, and their correlation with pneumonia extent (PnE) and outcome, we analyzed COVID-19 patients with an available previous chest CT, excluding those performed for cardiovascular disease. From February 21 to March 21, 2020, of 672 suspected COVID-19 patients from two centers who underwent CT, 45 RT-PCR-positives (28 males, median age 75, IQR 66-81 years) with previous CTs performed a median 36 months before (IQR 12-72 months) were included. We assessed PnE, pulmonary artery (PA) diameter, ascending aorta (Ao) diameter, and PA/Ao ratio. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.21037/qims-20-546DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7276354PMC

COVID-19 in patients with thoracic malignancies (TERAVOLT): first results of an international, registry-based, cohort study.

Lancet Oncol 2020 Jul 12;21(7):914-922. Epub 2020 Jun 12.

Vanderbilt Ingram Cancer Center, Vanderbilt University, Nashville, TN, USA.

Background: Early reports on patients with cancer and COVID-19 have suggested a high mortality rate compared with the general population. Patients with thoracic malignancies are thought to be particularly susceptible to COVID-19 given their older age, smoking habits, and pre-existing cardiopulmonary comorbidities, in addition to cancer treatments. We aimed to study the effect of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection on patients with thoracic malignancies. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S1470-2045(20)30314-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292610PMC

Clinical Outcomes After Percutaneous Patent Ductus Arteriosus Closure in Adults.

Can J Cardiol 2020 Jun 27;36(6):837-843. Epub 2019 Nov 27.

Toronto Congenital Cardiac Centre for Adults, Toronto General Hospital, Toronto, Canada. Electronic address:

Background: There is little published data regarding percutaneous patent ductus arteriosus (PDA) closure in adults. We aim to describe the outcomes of adult patients undergoing PDA closure at a single tertiary referral centre.

Methods: All adults who underwent device PDA closure at our centre from 2001 to 2017 were identified and enrolled in the study. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cjca.2019.11.025DOI Listing

Prognostic Value of Right Ventricular Two-Dimensional and Three-Dimensional Speckle-Tracking Strain in Pulmonary Arterial Hypertension: Superiority of Longitudinal Strain over Circumferential and Radial Strain.

J Am Soc Echocardiogr 2020 Jun 9. Epub 2020 Jun 9.

Department of Ultrasound, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People's Republic of China; Hubei Province Key Laboratory of Molecular Imaging, Wuhan, People's Republic of China. Electronic address:

Background: Right ventricular (RV) dysfunction is a predictor of adverse outcomes in patients with pulmonary arterial hypertension (PAH). Three-dimensional (3D) speckle-tracking echocardiography (STE) has been increasingly used to quantify RV function. However, the strain parameters evaluated by two-dimensional (2D) STE and 3D STE, which provide the most valuable clinical information, remain unknown. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.echo.2020.03.015DOI Listing

Assessment of ventilation-perfusion scans in patients with chronic thromboembolic pulmonary hypertension before and after surgery and correlation with clinical parameters.

Clin Imaging 2020 May 11;66:147-152. Epub 2020 May 11.

Imaging Institute, Cleveland Clinic, United States of America. Electronic address:

Purpose: We did a comparative analysis of matched and mismatched defects in pre- and post-operative V/Q scans in CTEPH patients. We correlated the number of these defects with pre-operative clinical and hemodynamic parameters.

Methods: This was a retrospective study on 27 patients with CTEPH who underwent surgery. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.clinimag.2020.04.041DOI Listing

Non-invasive prediction of tissue Doppler-derived E/e' ratio using lung Doppler signals.

Eur Heart J Cardiovasc Imaging 2020 Jun 12. Epub 2020 Jun 12.

Division of Cardiology, West Virginia University Heart and Vascular Institute, 1 Medical Center Drive, Morgantown, WV 26505, USA.

Aims: Lung Doppler signals (LDS) represent the radial movement of small pulmonary blood vessel walls, caused by pulse waves of cardiac origin. We sought to investigate the accuracy and prognostic value of LDS as a predictor of mitral valve early diastolic flow to annular velocity ratio (E/e'), in patients with acute decompensated heart failure (ADHF).

Methods And Results: We prospectively enrolled patients with ADHF (n = 99, mean age 65 ± 15 years, 61% males) who underwent echocardiographic and simultaneous LDS evaluation at hospital admission. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/ehjci/jeaa090DOI Listing

Clinical and diagnostic imaging findings in 37 rescued dogs with heartworm disease in Germany.

Authors:
Imke Maerz

Vet Parasitol 2020 May 30;283:109156. Epub 2020 May 30.

Tierklinik Hofheim GbR, Katharina Kemmler Straße 7, 65719, Hofheim am Taunus, Germany. Electronic address:

Canine dirofilariasis is currently uncommon in Germany, but its prevalence appears to be increasing due to rehoming of dogs from endemic areas. As part of staging of the disease, this case series describes clinical, radiological and echocardiographic findings in 37 dogs tested positive for Dirofilaria immitis between October 2016 and January 2019. Clinical history revealed 12 (32 %) asymptomatic and 22 (59 %) symptomatic dogs, with most of the dogs showing exercise intolerance, coughing or breathlessness. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.vetpar.2020.109156DOI Listing

Prognostic role of PET/MRI hybrid imaging in patients with pulmonary arterial hypertension.

Heart 2020 Jun 10. Epub 2020 Jun 10.

Department of Cardiology, Medical University of Bialystok, Bialystok, Poland

Objective: Right ventricular (RV) function is a major determinant of survival in patients with pulmonary arterial hypertension (PAH). Metabolic alterations may precede haemodynamic and clinical deterioration. Increased RV fluorodeoxyglucose (FDG) uptake in positron emission tomography (PET) was recently associated with progressive RV dysfunction in MRI, but the prognostic value of their combination has not been established. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/heartjnl-2020-316741DOI Listing

The Assessment of Myocardial Strain by Cardiac Imaging in Healthy Infants with Acute Bronchiolitis: A Systematic Review and Meta-Analysis.

Diagnostics (Basel) 2020 Jun 8;10(6). Epub 2020 Jun 8.

Pediatric Cardiology Division, Puerta del Mar University Hospital, 11009 Cadiz, Spain.

This study aims to systematically review the incidence of myocardial strain detected by echocardiography in previously healthy infants with acute bronchiolitis and its role as a predictor for adverse outcomes in this setting.

Methods: Pubmed/Medline, Excerpta Medica Data Base (EMBASE), and Cochrane Library were searched in April 2020 to identify original observational prospective studies that systematically performed echocardiography for the screening of myocardial strain in healthy infants with acute bronchiolitis. Pooled estimates were generated using random-effects models. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/diagnostics10060382DOI Listing

COVID-19 and Congenital Heart Disease: Results from a Nationwide Survey.

J Clin Med 2020 Jun 8;9(6). Epub 2020 Jun 8.

Department of Women's and Children's Health, University of Padua, 35122 Padua, Italy.

Background: The pandemic of Novel Coronavirus Disease 2019 (COVID-19) is challenging, given the large number of hospitalized patients. Cardiovascular co-morbidities are linked to a higher mortality risk. Thus, patients with Congenital Heart Disease (CHD) might represent a high-risk population. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/jcm9061774DOI Listing

Correlation Between Chest CT Findings and Clinical Features of 211 COVID-19 Suspected Patients in Wuhan, China.

Open Forum Infect Dis 2020 Jun 16;7(6):ofaa171. Epub 2020 May 16.

Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Background: Chest computed tomography (CT) has been widely used to assess pulmonary involvement in COVID-19. We aimed to investigate the correlation between chest CT and clinical features in COVID-19 suspected patients with or without fever.

Methods: We retrospectively enrolled 211 COVID-19 suspected patients who underwent both chest CT and reverse transcription polymerase chain reaction in Wuhan, China. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/ofid/ofaa171DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7239186PMC

The many faces and outcomes of pulmonary vein stenosis in early childhood.

Pediatr Pulmonol 2020 Jun 7. Epub 2020 Jun 7.

The Lillie Frank Abercrombie Section of Cardiology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas.

Pulmonary vein stenosis is a rare and poorly understood condition causing obstruction of the large pulmonary veins and of blood flow from the lungs to the left atrium. This results in elevated pulmonary venous pressure and pulmonary edema, pulmonary hypertension, potentially cardiac failure, and death. Clinical signs of the disease include failure to thrive, increasingly severe dyspnea, hemoptysis, respiratory difficulty, recurrent respiratory tract infections/pneumonia, cyanosis, and subcostal retractions. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/ppul.24848DOI Listing

Editorial for "Chronic Thromboembolic Pulmonary Hypertension Perioperative Monitoring Using Phase-Resolved Functional Lung (PREFUL)-MRI".

Authors:
Giulia Benedetti

J Magn Reson Imaging 2020 Jun 7. Epub 2020 Jun 7.

Radiology Department, Cardiothoracic Radiology, Guy's and St Thomas' NHS Foundation Trust, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jmri.27242DOI Listing

Pulmonary Embolism: A Practical Guide for the Busy Clinician.

Heart Fail Clin 2020 Jul;16(3):317-330

Department of Translational Medical Sciences, "Federico II" School of Medicine, "Federico II" University of Naples, Via Pansini 5, Naples 80131, Italy; Centre for Pulmonary Hypertension, Thoraxklinik at Heidelberg University Hospital. Electronic address:

Acute pulmonary embolism (PE) is the third most common acute cardiovascular condition, and its prevalence increases over time. D-dimer has a very high negative predictive value, and if normal levels of D-dimer are detected, the diagnosis of PE is very unlikely. The final diagnosis should be confirmed by computed tomographic scan. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.hfc.2020.03.004DOI Listing
July 2020
1.408 Impact Factor

"Pure" severe aortic stenosis without concomitant valvular heart diseases: echocardiographic and pathophysiological features.

Int J Cardiovasc Imaging 2020 Jun 4. Epub 2020 Jun 4.

Department of Cardiology, University Hospital Leipzig, Liebigstraße 20, 04103, Leipzig, Germany.

Purpose: In echocardiography the severity of aortic stenosis (AS) is defined by effective orifice area (EOA), mean pressure gradient (mPG) and transvalvular flow velocity (maxV). The hypothesis of the present study was to confirm the pathophysiological presence of combined left ventricular hypertrophy (LVH), diastolic dysfunction (DD) and pulmonary artery hypertension (PAH) in patients with "pure" severe AS.

Methods And Results: Patients (n = 306) with asymptomatic (n = 133) and symptomatic (n = 173) "pure" severe AS (mean age 78 ± 9. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10554-020-01907-4DOI Listing

Epidemiology of Renal Cell Carcinoma.

World J Oncol 2020 Jun 14;11(3):79-87. Epub 2020 May 14.

Allegheny Health Network, Pittsburgh, PA, USA.

Though renal cell carcinoma (RCC) accounts for 2% of global cancer diagnoses and deaths, it has more than doubled in incidence in the developed world over the past half-century, and today is the ninth most common neoplasm in the United States (US). While North America and Western Europe have the highest disease burden (with the Belarus highest in incidence), Latin America, Asia and Africa are projected to see an increase in incidence as nation's transition to a Western lifestyle. Most cases of RCC are discovered incidentally on imaging, and survival is highly dependent on the stage at diagnosis, with the metastatic disease having only a 12% 5-year survival rate. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.14740/wjon1279DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7239575PMC

Evidence of Accumulated Endothelial Progenitor Cells in the Lungs of Rats with Pulmonary Arterial Hypertension by Zr-oxine PET Imaging.

Mol Ther Methods Clin Dev 2020 Jun 3;17:1108-1117. Epub 2020 May 3.

State Key Laboratory of Medical Molecular Biology, Department of Cell Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and School of Basic Medicine, Peking Union Medical College, Beijing 100730, China.

Endothelial progenitor cells (EPCs) play a major role in regulating pulmonary vascular remodeling during pulmonary arterial hypertension (PAH) development. Several preclinical and clinical trials of EPCs transplantation have been performed for the treatment of PAH. However, there is no reliable method to monitor real-time cell trafficking and quantify transplanted EPCs. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.omtm.2020.04.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7256434PMC

Risk factors associated with pulmonary hemorrhage and hemoptysis following percutaneous CT-guided transthoracic lung core needle biopsy: a retrospective study of 1,090 cases.

Quant Imaging Med Surg 2020 May;10(5):1008-1020

Department of Radiology, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, China.

Background: Pulmonary hemorrhage and hemoptysis are the second-most common and potentially life-threatening complications after pneumothorax following percutaneous computed tomography-guided transthoracic lung biopsy (PCTLB). Preventing hemorrhagic complications after PCTLB requires an accurate estimation of risk factors. This study investigated the risk factors associated with pulmonary hemorrhage and hemoptysis following PCTLB, and whether the ratio of main pulmonary artery diameter (mPAD) to ascending aorta diameter (mPAD/AAD ratio) is a risk factor. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.21037/qims-19-1024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242316PMC

Undiagnosed Severe Late Complications of Repaired Tetralogy of Fallot.

Circ Cardiovasc Imaging 2020 Jun;13(6):e010273

Department of Cardiovascular and Thoracic Sciences, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy (R.L., E.P., F.G., A.M.L., M.G., F.C., M.M.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/CIRCIMAGING.119.010273DOI Listing

Quantification of Biventricular Function and Morphology by Cardiac Magnetic Resonance Imaging in Mice with Pulmonary Artery Banding.

J Vis Exp 2020 May 13(159). Epub 2020 May 13.

Center for Congenital Heart Diseases, Department of Pediatric Cardiology, University Medical Center Groningen, University of Groningen.

Right ventricular (RV) function and failure are major determinants of outcome in acquired and congenital heart diseases, including pulmonary hypertension. Assessment of RV function and morphology is complex, partly due to the complex shape of the RV. Currently, cardiac magnetic resonance (CMR) imaging is the golden standard for noninvasive assessment of RV function and morphology. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3791/60837DOI Listing

Chemotherapy-induced pulmonary complications in cancer: Significance of clinicoradiological correlation.

Indian J Radiol Imaging 2020 Jan-Mar;30(1):20-26. Epub 2020 Mar 30.

Department of Radiodiagnosis, Dr B.R.A. Institute Rotary Cancer Hospital, All India Institute of Medical Sciences, New Delhi, India.

Chemotherapy while revolutionizing cancer management by improving survival and quality of life; is also associated with several adverse effects. Lung is the most common organ affected in chemotherapy-related complications, due to either drug toxicity or more commonly due to infections caused by immunosuppression and less commonly due to immune-mediated injury. Radiology, when used in combination with clinical and lab data, can help reach the specific diagnosis or narrow down the differentials. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4103/ijri.IJRI_178_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7240883PMC

Relationship between clinical types and radiological subgroups defined by latent class analysis in 2019 novel coronavirus pneumonia caused by SARS-CoV-2.

Eur Radiol 2020 May 30. Epub 2020 May 30.

Department of Radiology, Changhai Hospital, The Navy Military Medical University, Changhai road 168, Shanghai, 200434, China.

Objectives: To investigate whether meaningful subgroups sharing the CT features of patients with COVID-19 pneumonia could be identified using latent class analysis (LCA) and explore the relationship between the LCA-derived subgroups and clinical types.

Methods: This retrospective review included 499 patients with confirmed COVID-19 pneumonia between February 11 and March 8, 2020. Subgroups sharing the CT features were identified using LCA. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00330-020-06973-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261041PMC

Pulmonary Vascular Disease Evaluation with Magnetic Resonance Angiography.

Radiol Clin North Am 2020 Jul 11;58(4):707-719. Epub 2020 May 11.

Department of Radiology, University of Wisconsin, 600 Highland Avenue, Madison, WI 53792, USA.

Pulmonary vascular assessment commonly relies on computed tomography angiography (CTA), but continued advances in magnetic resonance angiography have allowed pulmonary magnetic resonance angiography (pMRA) to become a reasonable alternative to CTA without exposing patients to ionizing radiation. pMRA allows the evaluation of pulmonary vascular anatomy, hemodynamic physiology, lung parenchymal perfusion, and (optionally) right and left ventricular function with a single examination. This article discusses pMRA techniques and artifacts; performance in commonly encountered pulmonary vascular diseases, specifically pulmonary embolism and pulmonary hypertension; and recent advances in both contrast-enhanced and noncontrast pMRA. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.rcl.2020.02.006DOI Listing

Internalization of Metal-Organic Framework Nanoparticles in Human Vascular Cells: Implications for Cardiovascular Disease Therapy.

Nanomaterials (Basel) 2020 May 27;10(6). Epub 2020 May 27.

Department of Biological and Environmental Sciences, Qatar University, Doha 2713, Qatar.

Cardiovascular diseases (CVDs) are the leading cause of morbidity and mortality worldwide. Alteration of endothelial cells and the underlying vasculature plays a central role in the pathogenesis of various CVDs. The application of nanoscale materials such as nanoparticles in biomedicine has opened new horizons in the treatment of CVDs. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/nano10061028DOI Listing

MitraClip as bridging strategy for heart transplantation in Chagas cardiomyopathy: a case report.

Eur Heart J Case Rep 2020 Feb 18;4(1):1-5. Epub 2020 Jan 18.

Division of Cardiology, Department of Heart Failure and Transplantation, Fundación Cardioinfantil, Universidad El Bosque, Calle 163A # 13B-60, Bogotá, Colombia.

Background: Patients with end-stage heart failure, suffering from severe pulmonary hypertension (PH) and elevated pulmonary vascular resistance, are not eligible for heart transplant due to high mortality risk and primary graft dysfunction. Severe PH may be favoured by functional severe mitral regurgitation, which is present in many cardiopathies like end-stage Chagasic cardiomyopathy.

Case Summary: We present a case of a young man with end-stage heart failure secondary to Chagas cardiomyopathy with severe functional mitral regurgitation (FMR) and severe PH. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/ehjcr/ytz238DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245051PMC
February 2020

Long-term outcome of liver transplantation for congenital extrahepatic portosystemic shunt.

Liver Transpl 2020 May 28. Epub 2020 May 28.

Department of Surgery, Kyoto University, Kyoto, Japan.

Liver transplantation (LT) may have been viewed as the "last resort" for the treatment of congenital extrahepatic portosystemic shunt (CEPS) due to advancement of imaging and interventional radiology techniques. However, some patients still require LT, and criteria for LT are yet to be determined. We conducted a national survey of cases undergoing LT for CEPS between June 1998 and August 2018 and evaluated the clinical data and outcomes with a review of previously reported cases from the English-language medical literature. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/lt.25805DOI Listing

Reduced pulmonary vascular reserve during stress echocardiography in confirmed pulmonary hypertension and patients at risk of overt pulmonary hypertension.

Int J Cardiovasc Imaging 2020 May 27. Epub 2020 May 27.

Institute of Clinical Physiology - C.N.R., Pisa, Italy.

Noninvasive estimation of systolic pulmonary artery pressure (SPAP) during exercise stress echocardiography (ESE) is recommended for pulmonary hemodynamics evaluation but remains flow-dependent. Our aim was to assess the feasibility of pulmonary vascular reserve index (PVRI) estimation during ESE combining SPAP with cardiac output (CO) or exercise-time and compare its value in three group of patients: with invasively confirmed pulmonary hypertension (PH), at risk of PH development (PH risk) mainly with systemic sclerosis and in controls (C) without clinical risk factors for PH, age-matched with PH risk patients. We performed semisupine ESE in 171 subjects: 31 PH, 61 PH at risk and 50 controls as well as in 29 young, healthy normals. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10554-020-01897-3DOI Listing

Pulmonary capillary haemangiomatosis: a distinct entity?

Eur Respir Rev 2020 Jun 27;29(156). Epub 2020 May 27.

Inserm UMR_S 999, Hôpital Marie Lannelongue, Le Plessis Robinson, France

Pulmonary capillary haemangiomatosis (PCH) is a rare and incompletely understood histopathological finding characterised by abnormal capillary proliferation within the alveolar interstitium, which has long been noted to share many overlapping features with pulmonary veno-occlusive disease (PVOD). But are PCH and PVOD distinct entities that occur in isolation, or are they closely intertwined manifestations along a spectrum of the same disease? The classic clinical features of both PCH and PVOD include signs and symptoms related to pulmonary hypertension, hypoxaemia, markedly impaired diffusion capacity of the lung and abnormal chest imaging with ground glass opacities, septal lines and lymphadenopathy. In recent years, increasing evidence suggests that the clinical presentation, histopathological features, genetic substrate and pathobiological mechanisms of PCH and PVOD are overlapping and usually indistinguishable. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1183/16000617.0168-2019DOI Listing

Contemporary usefulness of pulmonary venous flow parameters to estimate left ventricular end-diastolic pressure on transthoracic echocardiography.

Int J Cardiovasc Imaging 2020 May 21. Epub 2020 May 21.

Department of Cardiology, Dr. Siyami Ersek Cardiovascular and Thoracic Surgery Research and Training Hospital, Istanbul, Turkey.

Measurement of pulmonary venous flow (PVF) parameters can be used to estimate left ventricular end-diastolic pressure (LVEDP) on transthoracic echocardiography. Despite that, 2016 American Society of Echocardiography (ASE)/European Association of Cardiovascular Imaging (EACVI) algorithm gave a secondary role to PVF to assess left ventricular filling pressure. We aimed to test correlations between several PVF parameters, including novel measurements, with LVEDP and to analyze whether PVF parameters have an incremental usefulness over ASE/EACVI algorithm to estimate LVEDP. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10554-020-01886-6DOI Listing

Intensity and Distribution of Patchy Late Gadolinium Enhancement in Left Atrium in Patients With Atrial Fibrillation.

J Atr Fibrillation 2019 Oct-Nov;12(3):2206. Epub 2019 Oct 31.

Department of Clinical Electrophysiology, Federal State Budget Organization National Medical Research Center of Cardiology of the Ministry of Healthcare of the Russian Federation, Moscow, Russia.

Purpose: Late gadolinium enhancement (LGE) cardiac magnetic resonance imaging (MRI) studies were performed on healthy individuals to establish signal intensity thresholds for reproducible left atrial (LA) patchy LGE detection. Using established criteria, differences in LA patchy LGE between healthy volunteers (HV) and patients with atrial fibrillation (AF) or hypertension were analyzed.

Methods: Fifty-three patents with AF (mean age 56 years, 60% men), 25 patients with hypertension and no history of AF (mean age 54 years, 40% men), and 28 HV (mean age 50 years, 52% men) were enrolled in an observational, non-interventional, case-control prospective study. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4022/jafib.2206DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237097PMC
October 2019

Clinical analysis of 16 cases of pulmonary cryptococcosis in patients with normal immune function.

Ann Palliat Med 2020 May 15;9(3):1117-1124. Epub 2020 May 15.

Department of Pulmonary and Critical Care Medicine, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China.

Background: Pulmonary cryptococcosis (PC) is an invasive pulmonary fungal disease caused by Cryptococcus neoformans or Cryptococcus gattii. Cryptococcus is the opportunistic pathogen. Immune damage and chronic consumptive diseases are the high risk. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.21037/apm-20-897DOI Listing

A comprehensive echocardiographic method for risk stratification in pulmonary arterial hypertension.

Eur Respir J 2020 May 19. Epub 2020 May 19.

University Hospital Giessen und Marburg GmbH, Pulmonary Hypertension Division, Medical Clinic II, Giessen, Germany.

Question Addressed: Echocardiography is not currently considered as providing sufficient prognostic information to serve as an integral part of treatment goals in pulmonary arterial hypertension (PAH). We tested the hypothesis that incorporation of multiple parameters reflecting right heart function would improve the prognostic value of this imaging modality.

Methods And Main Results: We pooled individual patient data from a total of 517 patients (mean age 52±15 years, 64. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1183/13993003.00513-2020DOI Listing

Comparison of V/Q SPECT and CT Angiography for the Diagnosis of Chronic Thromboembolic Pulmonary Hypertension.

Radiology 2020 May 19:192181. Epub 2020 May 19.

From the Department of Nuclear Medicine (M.W., D.W., R.M., Z.Z., H.Z., K.H., L.W., W.F.) and Department of Cardiology, Center for Diagnosis and Management of Pulmonary Vascular Diseases (C.X.), Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, 167 Beilishi Road, Beijing 100037, China.

Background Accurate methods for identifying obstructions in both large and small vessels are crucial for diagnosis and treatment of chronic thromboembolic pulmonary hypertension (CTEPH). Purpose To compare the performance of ventilation-perfusion (V/Q) scanning, V/Q SPECT, and CT pulmonary angiography (PA) in CTEPH by using digital subtraction PA as the reference standard. Materials and Methods This prospective study was conducted from January 2016 to January 2018. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1148/radiol.2020192181DOI Listing

Caudal vena cava aneurysm in a cat with Eisenmenger Syndrome.

J Vet Med Sci 2020 Jun 15;82(6):784-787. Epub 2020 May 15.

Department of Veterinary Medical Imaging, College of Veterinary Medicine, Konkuk University, 05029, 120, Neungdong-ro, Gwangjin-gu, Seoul, Republic of Korea.

A seven-month-old cat was referred for evaluation of exercise intolerance and open-mouth breathing. Based on ultrasonographic examination, caudal vena cava (CVC) aneurysm associated with right congestive heart failure resulting from congenital heart disease was diagnosed. Conservative treatment for alleviating pulmonary hypertension mildly improved the clinical signs and decreased the heart size and CVC aneurysm diameter. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1292/jvms.19-0518DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7324822PMC

Tibetan , an allele with loss-of-function properties.

Proc Natl Acad Sci U S A 2020 Jun 15;117(22):12230-12238. Epub 2020 May 15.

Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104;

Tibetans have adapted to the chronic hypoxia of high altitude and display a distinctive suite of physiologic adaptations, including augmented hypoxic ventilatory response and resistance to pulmonary hypertension. Genome-wide studies have consistently identified compelling genetic signatures of natural selection in two genes of the Hypoxia Inducible Factor pathway, and The product of the former induces the degradation of the product of the latter. Key issues regarding Tibetan are whether it is a gain-of-function or loss-of-function allele, and how it might contribute to high-altitude adaptation. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1920546117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275716PMC
June 2020
9.809 Impact Factor