11,637 results match your criteria Pulmonary Hypertension Imaging


Non-Invasive Estimation of Right Atrial Pressure Using a Semi-Automated Echocardiographic Tool for Inferior Vena Cava Edge-Tracking.

J Clin Med 2022 Jun 7;11(12). Epub 2022 Jun 7.

Fondazione Toscana G. Monasterio, 56124 Pisa, Italy.

The non-invasive estimation of right atrial pressure () would be a key advancement in several clinical scenarios, in which the knowledge of central venous filling pressure is vital for patients' management. The echocardiographic estimation of RAP proposed by Guidelines, based on inferior vena cava (IVC) size and respirophasic collapsibility, is exposed to operator and patient dependent variability. We propose novel methods, based on semi-automated edge-tracking of IVC size and cardiac collapsibility (cardiac caval index-CCI), tested in a monocentric retrospective cohort of patients undergoing echocardiography and right heart catheterization (RHC) within 24 h in condition of clinical and therapeutic stability (170 patients, age 64 ± 14, male 45%, with pulmonary arterial hypertension, heart failure, valvular heart disease, dyspnea, or other pathologies). Read More

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Coexistence of Cor Triatriatum Sinister, Fibroelastoma and Pulmonary Veins Ostial Anatomy Variant as Incidental Findings in Coronary Computed Tomography Angiography.

Diagnostics (Basel) 2022 Jun 13;12(6). Epub 2022 Jun 13.

Department of Internal and Occupational Diseases, Hypertension and Clinical Oncology, Wroclaw Medical University, Borowska 213, PL 50-556 Wroclaw, Poland.

Coronary computed tomography angiography (CCTA) is a noninvasive examination whose main purpose is to exclude significant stenosis in the coronary arteries. The obtained computed tomography images may also provide information about other coexisting pathologies of the heart and vessels. The paper presents images of cardiac lesions in a 44-year-old hypertensive patient who underwent CCTA, based on which significant stenosis in the coronary arteries was excluded, the suspicion of a cor triatriatum sinister was confirmed and the presence of fibroelastoma and a variant of the anatomy of the pulmonary veins ostial was confirmed. Read More

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Dual-Energy Imaging of the Chest.

Semin Ultrasound CT MR 2022 Aug 26;43(4):311-319. Epub 2022 Mar 26.

Assistant Professor, Department of Radiology, University of Florida College of Medicine, Jacksonville, Florida, 32209, United States.

Dual-energy computed tomography (DECT) is a contemporary development by which the tissue can be characterized beyond conventional computed tomography. It improves tissue differentiation by exploiting the X-ray absorptive property of the tissues. Although still in its early stages, DECT utilization in pulmonary and cardiovascular pathologies is emerging. Read More

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Middle-Aged Case of Congenital Portosystemic Venous Shunt Complicated With Multiple Visceral Arterial Aneurysms and Aorto-Pulmonary Collateral Vessels.

Circ Cardiovasc Imaging 2022 Jun 23:101161CIRCIMAGING122013969. Epub 2022 Jun 23.

Department of Cardiovascular Medicine, The University of Tokyo. (K.G., Y.N., A.S., S.M., N.T., M.H., I.K.).

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Vascular anomaly diagnosis by central venous catheter misplacement: a case report.

J Med Case Rep 2022 Jun 22;16(1):259. Epub 2022 Jun 22.

Department of Radiology, Ikazia Hospital Rotterdam, Rotterdam, The Netherlands.

Background: Congenital heart diseases rarely have a primary manifestation in adulthood. They are a rare cause of pulmonary hypertension in adults.

Case Presentation: A 70-year-old woman of Eurasian descent underwent emergency surgery for bowel ischemia. Read More

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Four-Dimensional Flow Imaging to Evaluate Shunt Flow in a Unidirectional Valved Potts Shunt.

Circ Cardiovasc Imaging 2022 Jun 2;15(6):e014052. Epub 2022 Jun 2.

Division of Cardiology, Department of Pediatrics (M.P.D., A.S., E.B.R.), Columbia University Vagelos College of Physicians and Surgeons and NewYork-Presbyterian Morgan Stanley Children's Hospital.

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Cine magnetic resonance imaging detects shorter cardiac rest periods in postcapillary pulmonary hypertension.

Eur Heart J Cardiovasc Imaging 2022 Jun 20. Epub 2022 Jun 20.

Department of Radiology, Northwestern University, 737 N Michigan Avenue, Suite 1600, Chicago, IL 60611, USA.

Aims: A shorter cardiac rest period within a cardiac cycle is usually thought to be a result of a fast heart rate, and its clinical relevance has long been ignored. The aim of the present study was to test the hypothesis that the length of cardiac rest periods is altered in postcapillary pulmonary hypertension (PH).

Methods And Results: Twenty-six patients with postcapillary PH and 20 healthy controls were recruited for cardiac magnetic resonance imaging (MRI) scans. Read More

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Defining minimal detectable difference in echocardiographic measures of right ventricular function in systemic sclerosis.

Arthritis Res Ther 2022 Jun 18;24(1):146. Epub 2022 Jun 18.

Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, 1830 E. Monument Street, Room 540, Baltimore, MD, 21205, USA.

Background: Echocardiography (2DE) is integral for screening and longitudinal evaluation of pulmonary arterial hypertension (PAH) in systemic sclerosis (SSc). In the present study, we sought to establish the reliability, repeatability, and reproducibility of 2DE parameters in SSc patients with and without PAH and to define the minimal detectable difference (MDD), the smallest change detected beyond measurement error.

Methods: SSc patients without known PAH and with invasively confirmed PAH on stable therapies underwent 2DE with strain at two time points. Read More

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Risk Stratification and Outcomes in Patients With Pulmonary Hypertension: Insights into Right Ventricular Strain by MRI Feature tracking.

J Magn Reson Imaging 2022 Jun 17. Epub 2022 Jun 17.

Department of Magnetic Resonance Imaging, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

Background: Despite a recommended multidimensional approach for pulmonary hypertension (PH) risk stratification and guidance of treatment decisions, this may not always be achievable in patients with advanced disease. One issue is the lack of an imaging modality to assess right ventricular (RV) structure and function abnormalities.

Purpose: To explore the risk stratification and prognostic value of cardiac MR feature tracking (MR-FT)-derived RV strain. Read More

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Incidentally Diagnosed Double Inferior Vena Cava While Being Investigated for Pulmonary Hypertension.

Anatol J Cardiol 2022 06;26(6):E8-E9

Department of Cardiology, Gülhane Training and Research Hospital, University of Health Sciences, Ankara, Turkey.

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Editorial for "Risk Stratification and Outcomes in Patients with Pulmonary Hypertension: Insights into Right Ventricular Strain by MRI Feature-Tracking".

J Magn Reson Imaging 2022 Jun 14. Epub 2022 Jun 14.

Department of Cardiology, Royal North Shore Hospital, Sydney, New South Wales, Australia.

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Systemic sclerosis in Native Americans of the American Southwest.

Int J Rheum Dis 2022 Jun 14. Epub 2022 Jun 14.

Division of Rheumatology and School of Medicine, Department of Internal Medicine, University of New Mexico Health Sciences Center, Albuquerque, New Mexico, USA.

Objective: Many indigenous non-Caucasian populations, including Native Americans, have been reported to have higher rates, distinct clinical phenotypes, increased complications, and greater severity of systemic sclerosis (SSc). However, little is known of SSc specifically in Native Americans of the American Southwest. This study compared the clinical and serologic manifestations and outcomes of SSc in Native Americans and non-Native Americans (non-Natives) of this region. Read More

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Idiopathic pulmonary arterial hypertension patients with a high HFPEF-score: Insights from the Amsterdam UMC PAH-cohort.

J Heart Lung Transplant 2022 May 20. Epub 2022 May 20.

Amsterdam Cardiovascular Sciences, Pulmonary Hypertension and Thrombosis, Amsterdam, the Netherlands; Amsterdam UMC location Vrije Universiteit Amsterdam, Department of Cardiology, de Boelelaan 1117, Amsterdam, Netherlands. Electronic address:

Background: The idiopathic pulmonary arterial hypertension (iPAH) phenotype is changing from a predominantly young female patient to an older, frequently obese patient of either sex. Many newly diagnosed iPAH-patients have risk factors for left ventricular diastolic dysfunction (LVDD), possibly affecting management and treatment.

Aim: To determine whether the HFPEF-score identifies a subgroup of iPAH-patients with blunted response to PAH-targeted treatment. Read More

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Chest computed tomography findings of ground-glass nodules with enhancing central vessel/nodule in pediatric patients with BMPR2 mutations and plexogenic arteriopathy.

Pediatr Radiol 2022 Jun 11. Epub 2022 Jun 11.

Department of Pathology and Laboratory Medicine, Children's Hospital Colorado, Aurora, CO, USA.

Background: Germline mutation in bone morphogenetic protein type II (BMPR2) is the most common cause of idiopathic/heritable pulmonary hypertension in pediatric patients. Despite the discovery of this gene there are no known descriptions of the CT or CT angiography findings in these children.

Objective: To correlate the clinical presentation, pathology and chest CT findings in pediatric patients with pulmonary hypertension caused by mutations in the BMPR2 gene. Read More

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A Thyrotoxicosis Surprise: Jod-Basedow Phenomenon Following IV Contrast Administration.

Cureus 2022 May 4;14(5):e24742. Epub 2022 May 4.

Endocrinology, Brookdale University Hospital Medical Center, Brooklyn, USA.

Jod-Basedow phenomenon (JBP) is a rare thyrotoxic condition due to increased exogenous iodine exposure, also known as iodine-induced hyperthyroidism (IIH). Historically JBP was typically seen in iodine-deficient patients when exposed to increased amounts of iodine. However, in today's era, the most common cause of JBP is exposure to iodinated contrast media commonly used in various radiological examinations and interventional procedures, resulting in massive iodine exposure. Read More

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Bronchiectasis: Retrospective Analysis of Clinical and Pathological Findings in a Tertiary-Care Hospital.

Int J Clin Pract 2022 31;2022:8773204. Epub 2022 Jan 31.

Department of Thoracic Surgery, Inonu University School of Medicine, Malatya, Turkey.

Background: Bronchiectasis is still a challenging chronic lung disease in developing countries. Patients with bronchiectasis can also have pulmonary hypertension. There are sparse data on the prevalence of pulmonary hypertension in patients with bronchiectasis. Read More

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Prolapsing left atrial mass causing severe pulmonary hypertension in a new cardiac service in a rural hospital in Cameroon: a case report.

Pan Afr Med J 2022 11;41:196. Epub 2022 Mar 11.

Faculty of Medicine and Biomedical Sciences, University of Yaoundé I, Yaoundé, Cameroon.

We report a case of a left atrial mass in a 62-year-old patient with no relevant past history. He presented with dyspnea of 1 year duration. Clinical examination revealed a blood pressure of 130/82mmHg, a heart rate of 80 beats per minute. Read More

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Prevalence and Natural History of Mitral Annulus Calcification and Related Valve Dysfunction.

Mayo Clin Proc 2022 Jun;97(6):1094-1107

Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN. Electronic address:

Objective: To evaluate the prevalence and natural history of mitral annulus calcification (MAC) and associated mitral valve dysfunction (MVD) in patients undergoing clinically indicated echocardiography.

Methods: A retrospective review was conducted of all adults who underwent echocardiography in 2015. Mitral valve dysfunction was defined as mitral regurgitation or mitral stenosis (MS) of moderate or greater severity. Read More

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A Brief Review on Gender Differences in Mexican-Mestizo Patients with Pulmonary Arterial Hypertension (PAH) at a Tertiary-Level Hospital.

Curr Probl Cardiol 2022 Jun 2:101275. Epub 2022 Jun 2.

Cardiorespiratory Emergencies, Hospital General de Mexico "Dr. Eduardo Liceaga", 06720, Mexico City, Mexico. Electronic address:

Introduction: Pulmonary hypertension (PH) is a hemodynamic condition with different etiological groups but common pathophysiology. Gender differences have been studied in group 1 of the PH classification, the pulmonary arterial hypertension (PAH) group. PAH has an etiopathogenic basis in sex hormones and directly affects the pulmonary vasculature and the heart. Read More

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Myocardial extracellular volume quantification by cardiac CT in pulmonary hypertension: Comparison with cardiac MRI.

Eur J Radiol 2022 Aug 30;153:110386. Epub 2022 May 30.

Department of Diagnostic Radiology, Faculty of Life Sciences, Kumamoto University, 1-1-1 Honjyo, Chuo-ku, Kumamoto 860-8556, Japan.

Purpose: Myocardial extracellular volume (ECV) measured by cardiac magnetic resonance imaging (MRI) has been suggested as a marker of disease severity in pulmonary hypertension (PH). However, consistency between ECVs quantified by computed tomography (CT) and MRI has not been sufficiently investigated in (PH). We investigated the utility of CT-ECV in PH, using MRI-ECV as a reference standard. Read More

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Synthesis and preclinical evaluation of [C]LR111 and [F]EW-7197 as PET tracers of the activin-receptor like kinase-5.

Nucl Med Biol 2022 May 24;112-113:9-19. Epub 2022 May 24.

Amsterdam UMC, VU University Medical Center, Radiology & Nuclear Medicine (Amsterdam Cardiovascular Sciences), de Boelelaan 1085c, Amsterdam, the Netherlands.

The transforming growth factor β (TGFβ) pathway plays a complex role in cancer biology, being involved in both tumour suppression as well as promotion. Overactive TGFβ signalling has been linked to multiple diseases, including cancer, pulmonary arterial hypertension, and fibrosis. One of the key meditators within this pathway is the TGFβ type I receptor, also termed activin receptor-like kinase 5 (ALK5). Read More

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Right heart failure: A narrative review for emergency clinicians.

Am J Emerg Med 2022 May 25;58:106-113. Epub 2022 May 25.

SAUSHEC, Emergency Medicine, Brooke Army Medical Center, Fort Sam Houston, TX, USA. Electronic address:

Introduction: Right heart failure (RHF) is a clinical syndrome with impaired right ventricular cardiac output due to a variety of etiologies including ischemia, elevated pulmonary arterial pressure, or volume overload. Emergency department (ED) patients with an acute RHF exacerbation can be diagnostically and therapeutically challenging to manage.

Objective: This narrative review describes the pathophysiology of right ventricular dysfunction and pulmonary hypertension, the methods to diagnose RHF in the ED, and management strategies. Read More

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Ultrasound guided pulmonary artery catheter insertion: An alternative to fluoroscopic guidance.

Respir Med Case Rep 2022 25;38:101678. Epub 2022 May 25.

Division of Pulmonary Disease, Critical Care and Sleep Medicine, Case Western Reserve University, MetroHealth Medical Center, Cleveland, OH, USA.

Pulmonary artery catheters (PACs) can provide extremely valuable objective data in select patients. They are usually advanced by floatation of balloon tip along the normal blood flow and their placement is confirmed under pressure waveform guidance. Imaging such as fluoroscopy is often employed in low flow states and in cardiac catheterization suite to reduce the failure rate and time to wedge; but is not readily available at bedside. Read More

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Cardiac Imaging in Patients After Fontan Palliation: Which Test and When?

Front Pediatr 2022 16;10:876742. Epub 2022 May 16.

Department of Cardiac Surgery, Cardiology, Heart and Lung Transplantation Bambino Gesu' Children's Hospital, IRCCS, Rome, Italy.

The Fontan operation represents the final stage of a series of palliative surgical procedures for children born with complex congenital heart disease, where a "usual" biventricular physiology cannot be restored. The palliation results in the direct connection of the systemic venous returns to the pulmonary arterial circulation without an interposed ventricle. In this unique physiology, systemic venous hypertension and intrathoracic pressures changes due to respiratory mechanics play the main role for propelling blood through the pulmonary vasculature. Read More

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Congenital diaphragmatic hernia.

Nat Rev Dis Primers 2022 06 1;8(1):37. Epub 2022 Jun 1.

Department of Surgery, Division of Paediatric Surgery, Paediatrics & Child Health, Physiology & Pathophysiology, University of Manitoba, Winnipeg, Manitoba, Canada.

Congenital diaphragmatic hernia (CDH) is a rare birth defect characterized by incomplete closure of the diaphragm and herniation of fetal abdominal organs into the chest that results in pulmonary hypoplasia, postnatal pulmonary hypertension owing to vascular remodelling and cardiac dysfunction. The high mortality and morbidity rates associated with CDH are directly related to the severity of cardiopulmonary pathophysiology. Although the aetiology remains unknown, CDH has a polygenic origin in approximately one-third of cases. Read More

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Prognostic value of systemic inflammatory response syndrome after transcatheter aortic valve implantation.

J Cardiovasc Med (Hagerstown) 2022 Jun;23(6):394-398

Department of Clinical, Internal, Anaesthesiology and Cardiovascular Sciences, 'Sapienza' University of Rome, Policlinico Umberto I, Rome, Italy.

Aims: Systemic inflammatory response syndrome (SIRS) could affect mortality after transcatheter aortic valve implantation (TAVI) up to 12 months of follow-up. The aim of this study was to evaluate the prevalence of SIRS after TAVI and its impact on all-cause mortality up to 24 months follow-up.

Methods: We retrospectively enrolled 132 patients with symptomatic severe aortic stenosis undergoing TAVI. Read More

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Chronic Thromboembolic Pulmonary Hypertension.

Lung 2022 Jun 29;200(3):283-299. Epub 2022 May 29.

Division of Biological Sciences, Department of Medicine, University of Chicago, 5841 S. Maryland Avenue, Chicago, IL, 60637, USA.

Chronic thromboembolic pulmonary hypertension (CTEPH), defined as precapillary pulmonary hypertension (PH) by right heart catheterization and imaging consistent with chronic thromboembolism, is a long-term complication of pulmonary embolism (PE). Pathobiological mechanisms involve pulmonary artery occlusion from organized thromboembolic material despite at least three months of uninterrupted therapeutic anticoagulation following acute PE and secondary microvasculopathy. Delay in diagnosis and management of CTEPH is associated with poor outcomes. Read More

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Diagnosis and management of pulmonary hypertension in infants with bronchopulmonary dysplasia.

Semin Fetal Neonatal Med 2022 May 26:101351. Epub 2022 May 26.

Division of Newborn Medicine, Boston Children's Hospital and Department of Pediatrics, Harvard Medical School, Boston, MA, USA. Electronic address:

Chronic pulmonary hypertension of infancy (cPHi) is a heterogeneous disease process that contributes to morbidity and mortality in preterm infants. cPHi is most commonly associated with chronic lung disease of prematurity and represents a unique phenotype of bronchopulmonary dysplasia. It is characterized by persistently elevated or newly rising pulmonary vascular resistance and pulmonary artery pressure beyond the first weeks of age. Read More

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Implementation of a Longitudinal Critical Care Fellowship Ultrasound Curriculum.

ATS Sch 2022 Mar 28;3(1):125-134. Epub 2022 Jan 28.

Section of Pulmonary/Critical Care and Allergy/Immunology, Louisiana State University Health Sciences Center, New Orleans, Louisiana; and.

Background: The use of point-of-care ultrasound as a diagnostic and interventional tool is rapidly becoming standard of care in critical care medicine; a standardized training curriculum is needed to ensure provider proficiency.

Objective: This study aimed to describe a longitudinal critical care ultrasound (CCUS) curriculum in a pulmonary critical care medicine (PCCM) fellowship training program. It evaluated the curriculum's impact on fellows' knowledge, skills, and self-reported confidence and retention of these attributes. Read More

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