1,871 results match your criteria Pulmonary Edema Cardiogenic


Diagnostic Accuracy of Point-of-Care Lung Ultrasonography and Chest Radiography in Adults With Symptoms Suggestive of Acute Decompensated Heart Failure: A Systematic Review and Meta-analysis.

JAMA Netw Open 2019 Mar 1;2(3):e190703. Epub 2019 Mar 1.

Division of Cardiology, University of Colorado School of Medicine, Aurora.

Importance: Standard tools used to diagnose pulmonary edema in acute decompensated heart failure (ADHF), including chest radiography (CXR), lack adequate sensitivity, which may delay appropriate diagnosis and treatment. Point-of-care lung ultrasonography (LUS) may be more accurate than CXR, but no meta-analysis of studies directly comparing the 2 tools was previously available.

Objective: To compare the accuracy of LUS with the accuracy of CXR in the diagnosis of cardiogenic pulmonary edema in adult patients presenting with dyspnea. Read More

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http://jamanetworkopen.jamanetwork.com/article.aspx?doi=10.1
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http://dx.doi.org/10.1001/jamanetworkopen.2019.0703DOI Listing
March 2019
3 Reads

Early high-flow nasal cannula oxygen therapy in adults with acute hypoxemic respiratory failure in the ED: A before-after study.

Am J Emerg Med 2019 Mar 5. Epub 2019 Mar 5.

INSERM CIC-1402, ALIVE, Université de Poitiers, Faculté de Médecine et de Pharmacie, Poitiers, France; CHU de Poitiers, Réanimation Médicale, Poitiers, France.

Objectives: To compare clinical impact after early initiation of high-flow nasal cannula oxygen therapy (HFNC) versus standard oxygen in patients admitted to an emergency department (ED) for acute hypoxemic respiratory failure.

Methods: We performed a prospective before-after study at EDs in two centers including patients with acute hypoxemic respiratory failure defined by a respiratory rate above 25 breaths/min or signs of increased breathing effort under additional oxygen for a pulse oximetry above 92%. Patients with cardiogenic pulmonary edema or exacerbation of chronic lung disease were excluded. Read More

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http://dx.doi.org/10.1016/j.ajem.2019.03.004DOI Listing
March 2019
2 Reads

Left ventricular decompression in veno-arterial extracorporeal membrane oxygenation.

Ann Cardiothorac Surg 2019 Jan;8(1):9-18

Department of Cardiothoracic, Transplantation and Vascular Surgery, S. Orsola Hospital, Bologna University, Bologna, Italy.

Background: Despite the survival benefit of veno-arterial extracorporeal membrane oxygenation (VA-ECMO) for treatment of refractory cardiogenic shock, it can also have potentially deleterious effects of left ventricular overload and pulmonary edema. The objective of this review was to investigate the current evidence on the incidence, diagnosis, risk factors, prevention, and interventions for left ventricular overload in adult and pediatric VA-ECMO patients.

Methods: Five electronic databases, including MEDLINE, EMBASE, PubMed, Cochrane Central Register of Controlled Trials (CENTRAL), and Cochrane Database of Systematic Reviews, were searched for original published studies from their dates of inception to January 2018. Read More

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http://dx.doi.org/10.21037/acs.2018.11.07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379183PMC
January 2019
1 Read

Transfusion-associated circulatory overload and transfusion-related acute lung injury.

Blood 2019 Feb 26. Epub 2019 Feb 26.

Division of Hematology and Transfusion Medicine, Lund University, Lund, Sweden.

Transfusion-associated circulatory overload (TACO) and Transfusion-related acute lung injury (TRALI) are syndromes of acute respiratory distress which occur within 6 hours of blood transfusion. TACO and TRALI are the leading causes of transfusion-related fatalities and specific therapies are unavailable. Diagnostically, it remains very challenging to distinguish TACO and TRALI from underlying causes of lung injury and/or fluid overload as well as from each other. Read More

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http://dx.doi.org/10.1182/blood-2018-10-860809DOI Listing
February 2019

Acute Respiratory Failure in Renal Transplant Recipients: A Single Center Experience.

Exp Clin Transplant 2019 01;17(Suppl 1):172-174

From the Pulmonary Medicine, Baskent University, Adana, Turkey.

Objectives: We evaluated the frequency and cause of acute respiratory failure in renal transplant recipients.

Materials And Methods: Our single-center retrospective observational study included consecutive renal transplant recipients who were admitted to an intensive care unit for acute respiratory failure between 2011 and 2017. Acute respiratory failure was defined as oxygen saturation < 92% or partial pressure of oxygen in arterial blood < 60 mm Hg on room air and/or requirement of noninvasive or invasive mechanical ventilation. Read More

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http://www.ectrx.org/forms/ectrxcontentshow.php?doi_id=10.60
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http://dx.doi.org/10.6002/ect.MESOT2018.P49DOI Listing
January 2019
3 Reads

Late Presentation of Transfusion-related Acute Lung Injury in the Emergency Department.

Clin Pract Cases Emerg Med 2019 Feb 7;3(1):33-35. Epub 2019 Jan 7.

San Antonio Uniformed Services Health Education Consortium, Department of Emergency Medicine, San Antonio, Texas.

Transfusion-related acute lung injury (TRALI) is a complication of blood product transfusion characterized by respiratory distress with bilateral lung infiltrates and non-cardiogenic pulmonary edema developing within six hours of transfusion. TRALI is believed to result from an immunological response to transfused blood products. TRALI is a clinical diagnosis that requires the exclusion of other etiologies of pulmonary edema and acute lung injury. Read More

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http://dx.doi.org/10.5811/cpcem.2018.11.40592DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366380PMC
February 2019
3 Reads

Early Use of Norepinephrine in Septic Shock Resuscitation (CENSER) : A Randomized Trial.

Am J Respir Crit Care Med 2019 Feb 1. Epub 2019 Feb 1.

Mahidol University Faculty of Medicine Siriraj Hospital, 65106, Office of Research and Development, Bangkok, Thailand.

Rationale: Recent retrospective evidence suggests the efficacy of early norepinephrine administration during resuscitation; however, prospective data to support this assertion are scarce.

Objectives: To conduct a Phase II trial evaluating the hypothesis that early low-dose norepinephrine in adults sepsis with hypotension increases shock control by six hours compared with standard care.

Methods: This single-center, randomized, double-blind, placebo-controlled clinical trial was conducted at Siriraj Hospital, Bangkok, Thailand. Read More

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http://dx.doi.org/10.1164/rccm.201806-1034OCDOI Listing
February 2019
3 Reads

Major Cardiac Events in Patients Admitted to Intensive Care After Vascular Noncardiac Surgery: A Retrospective Cohort.

Semin Cardiothorac Vasc Anesth 2019 Jan 25:1089253218825442. Epub 2019 Jan 25.

1 São João Hospital Centre, Porto, Portugal.

Introduction: Patients proposed to vascular noncardiac surgery (VS) have several comorbidities associated with major adverse cardiac events (MACE). We evaluated incidence, predictors, and outcomes, and compared different scores to predict MACE after VS.

Methods: We included all patients admitted from 2006 to 2013. Read More

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http://dx.doi.org/10.1177/1089253218825442DOI Listing
January 2019
4 Reads

Phosgene-induced lung edema: Comparison of clinical criteria for increased extravascular lung water content with postmortem lung gravimetry and lavage-protein in rats and dogs.

Toxicol Lett 2019 May 19;305:32-39. Epub 2019 Jan 19.

Department of Toxicology, Fourth Military Medical University, China; Covestro Deutschland AG, Global Phosgene Steering Group, Leverkusen, Germany; Hanover Medical School, Hannover, Germany. Electronic address:

Phosgene-induced acute lung injury (ALI) is characterized by a concentration x time (Cxt)-dependent increased pulmonary vascular permeability, phenotypically manifested as potentially life-threatening acute lung edema. In contemporary animal bioassays, the quantification of protein in bronchoalveolar lavage fluid (BAL) is taken as an unequivocal endpoint suggestive of disruption of alveolar barrier function. However, extravasated protein can only be a surrogate endpoint for assessing the extravascular fluid dynamics of the lung. Read More

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http://dx.doi.org/10.1016/j.toxlet.2019.01.006DOI Listing
May 2019
11 Reads

Treatment of Hypertensive Cardiogenic Edema with Intravenous High-Dose Nitroglycerin in a Patient Presenting with Signs of Respiratory Failure: A Case Report and Review of the Literature.

Am J Case Rep 2019 Jan 21;20:83-90. Epub 2019 Jan 21.

Department of Internal Medicine, San Juan City Hospital, San Juan, Puerto Rico.

BACKGROUND Pulmonary edema is the accumulation of fluid in the lung secondary to increased hydrostatic pressure. Hypertensive cardiogenic pulmonary edema presents with a sudden onset of severe dyspnea, tachycardia, and tachypnea, and can occur when the systolic blood pressure exceeds 160 mmHg in association with acute decompensated congestive cardiac failure (CCF). A case is presented of hypertensive cardiogenic pulmonary edema treated with high-dose nitroglycerin and includes a review of the literature. Read More

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https://www.amjcaserep.com/abstract/index/idArt/913250
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http://dx.doi.org/10.12659/AJCR.913250DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350673PMC
January 2019
12 Reads

Late T-wave inversion following resolution of non-ischemic acute pulmonary edema.

Clin Case Rep 2019 Jan 12;7(1):224-226. Epub 2018 Nov 12.

Department of Clinical Therapeutics, Medical School "Alexandra" Hospital, National and Kapodistrian University of Athens Athens Greece.

Electrocardiographic (ECG) changes occurring several hours after the onset of acute cardiogenic pulmonary edema have been seldom described. The proposed explanatory mechanisms are various and not fairly established. In the absence of significant coronary artery disease, these ECG abnormalities could be attributed to mechanisms implicated in coronary microcirculatory dysfunction. Read More

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http://doi.wiley.com/10.1002/ccr3.1899
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http://dx.doi.org/10.1002/ccr3.1899DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332780PMC
January 2019
8 Reads

Coughing in dogs: what is the evidence for and against a cardiac cough?

Authors:
L Ferasin C Linney

J Small Anim Pract 2019 Mar 16;60(3):139-145. Epub 2019 Jan 16.

Willows Veterinary Referral Service, Solihull, West Midlands B90 4NH, UK.

Cough has been historically reported as a major clinical sign of cardiogenic pulmonary oedema in dogs. However, recent evidence appears to contradict the traditional dogmatic approach that linked cough to congestive heart failure in dogs. Here we use a question-based format to introduce and discuss the modern evidence regarding "cardiac cough" and the interpretation of this important but often misleading clinical sign. Read More

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http://dx.doi.org/10.1111/jsap.12976DOI Listing
March 2019
3 Reads

Safe Exchange of a Transfemoral Impella Pump.

Cardiovasc Revasc Med 2018 Dec 19. Epub 2018 Dec 19.

Cardiac Arrest Center, Advanced Heart Failure Unit, Department of Cardiology and Angiology, Hannover Medical School, Hannover, Germany.

Mechanical circulatory support with the Impella pump is established in many centers treating patients with cardiogenic shock. While Impella pumps usually run very stable, it may still be possible that one needs to remove the pump for using the same vascular access for different reasons. Unfortunately, until now it had been nearly impossible to remove the pump while preserving arterial access without severe bleeding. Read More

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http://dx.doi.org/10.1016/j.carrev.2018.12.006DOI Listing
December 2018
4 Reads

Clinical Pharmacokinetics, Safety, and Tolerability of a Novel, First-in-Class TRPV4 Ion Channel Inhibitor, GSK2798745, in Healthy and Heart Failure Subjects.

Am J Cardiovasc Drugs 2019 Jan 14. Epub 2019 Jan 14.

GlaxoSmithKline Clinical Unit Cambridge, Addenbrooke's Hospital, Cambridge, UK.

Introduction And Objective: Pulmonary capillary endothelial transient receptor potential vanilloid 4 (TRPV4) channel plays a critical role in mediating the development of cardiogenic pulmonary edema. GSK2798745 is a first-in-class, highly potent, selective, orally active TRPV4 channel blocker being evaluated in a first-time-in-humans study (NCT02119260).

Methods: GSK2798745 was administered in a randomized, placebo-controlled study design to healthy volunteers in three separate cohorts as single escalating doses, with and without food, and as once-daily repeat doses for up to 14 days, respectively. Read More

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http://dx.doi.org/10.1007/s40256-018-00320-6DOI Listing
January 2019
2 Reads

ST-Elevation Myocardial Infarction in Patients With Malignancies.

Kardiologiia 2018 Dec 25;58(12):5-12. Epub 2018 Dec 25.

Samara State Medical University.

Acute myocardial infarction (MI), the most severe complication of coronary artery disease, develops in 2-4% of patients with various malignancies.

Purpose: to explore the specific properties of ST-segment elevation myocardial infarction (STEMI) course in patients with cancer and its effect on short-term outcome.

Materials And Methods: We included in this study 45 patients with STEMI and history of cancer hospitalized in the period from 01. Read More

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http://dx.doi.org/10.18087/cardio.2018.12.10204DOI Listing
December 2018
3 Reads

Assessment of dyspneic patients in the emergency department using point-of-care lung and cardiac ultrasonography-a prospective observational study.

J Thorac Dis 2018 Nov;10(11):6221-6229

Emergency Medicine Department, National University Hospital, National University Health System, Singapore.

Background: Lung ultrasonography is increasingly used in the emergency department (ED) as a standard adjunct in the evaluation of the breathless patient. The study objective was to ascertain the diagnostic accuracy of lung and cardiac ultrasound in undifferentiated dyspneic ED patients.

Methods: We conducted this prospective observational study on patients presenting with dyspnea in the ED of a tertiary hospital. Read More

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http://dx.doi.org/10.21037/jtd.2018.10.30DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6297429PMC
November 2018
2 Reads

Giant Negative T Waves and QT Prolongation in Non-cardiogenic Pulmonary Edema: A Case Report and Review of Literature.

Cureus 2018 Oct 8;10(10):e3423. Epub 2018 Oct 8.

Department of Internal Medicine, University of Missouri-Columbia, Columbia, USA.

Giant negative T-waves have been linked to several cardiac and non-cardiac conditions. However, the presence of giant negative T-waves with QT prolongation in the setting of non-cardiogenic pulmonary edema is a rarely reported, female predominant, and poorly understood electrocardiographic phenomenon. We report a case of a 28-year-old white female who presented with acute diarrhea and was admitted due to acute kidney injury caused by a hemolytic uremic syndrome (HUS). Read More

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http://dx.doi.org/10.7759/cureus.3423DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314535PMC
October 2018
2 Reads

Papillary Muscle Dysfunction Due to Coronary Slow-Flow Phenomenon Presenting with Acute Mitral Regurgitation and Unilateral Pulmonary Edema.

Indian J Crit Care Med 2018 Nov;22(11):806-808

Department of Critical Care Medicine, Narayana Multispecialty Hospital, Bengaluru, Karnataka, India.

Cardiogenic pulmonary edema usually presents with characteristic clinical features and bilateral infiltrates on the chest radiograph. Rarely, pulmonary edema may manifest unilaterally, leading to a mistaken diagnosis of a primary lung pathology. We present a 30-year-old man who developed acute coronary syndrome following an overdose of alprazolam. Read More

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http://dx.doi.org/10.4103/ijccm.IJCCM_343_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6259443PMC
November 2018
2 Reads

A real life evaluation of non invasive ventilation in acute cardiogenic pulmonary edema: a multicenter, perspective, observational study for the ACPE SIMEU study group.

BMC Emerg Med 2018 12 29;18(1):61. Epub 2018 Dec 29.

Emergency Medicine Department, ASST Papa Giovanni XIII, Bergamo, Italy.

Background: During the past three decades conflicting evidences have been published on the use of non-invasive ventilation (NIV) in patients with acute cardiogenic pulmonary edema (ACPE). The aim of this study is to describe the management of acute respiratory failure (ARF) due to ACPE in twelve Italian emergency departments (EDs). We evaluated prevalence, characteristics and outcomes of ACPE patients treated with oxygen therapy, continuous positive airway pressure (CPAP) or Bi-level positive airway pressure (BiPAP) on admission to the EDs. Read More

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http://dx.doi.org/10.1186/s12873-018-0216-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310941PMC
December 2018
3 Reads

Thrombo-embolic complications in takotsubo syndrome: Review and demonstration of an illustrative case.

Clin Cardiol 2019 Feb 3;42(2):312-319. Epub 2019 Jan 3.

Coronary Artery Disease Area, Heart and Vascular Theme, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden.

Thrombo-embolism is one of the serious complications of takotsubo syndrome (TS) in addition to heart failure, pulmonary edema, cardiogenic shock, cardiac arrest, life-threatening arrhythmias, left ventricular outlet tract obstruction, mitral regurgitation, cardiac rupture, and death. The most common cardio-embolic events in TS are cerebral, renal, and peripheral embolism. Approximately, one-third of patients with left ventricular thrombus (LVT) in TS develop embolic complications. Read More

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http://dx.doi.org/10.1002/clc.23137DOI Listing
February 2019
5 Reads

Pulmonary Production of Soluble ST2 in Heart Failure.

Circ Heart Fail 2018 Dec;11(12):e005488

IMIB-Arrixaca, University of Murcia, Spain (M.T.P.-M., M.C.A.-L., C.M.M., A.L.).

Background: Serum concentrations of ST2 (interleukin-1 receptor-like 1) represent a meaningful prognostic marker in cardiac diseases. Production of soluble ST2 (sST2) may be partially extracardiac. Identification of sST2 sources is relevant to design strategies for modulating its signaling. Read More

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https://www.ahajournals.org/doi/10.1161/CIRCHEARTFAILURE.118
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http://dx.doi.org/10.1161/CIRCHEARTFAILURE.118.005488DOI Listing
December 2018
7 Reads

Subendocardial Ischemia Because of Coronary Artery Spasm Causes Transient Severe Mitral Regurgitation.

Circ Heart Fail 2018 Dec;11(12):e005496

Department of Cardiology, Tokyo Metropolitan Police Hospital, Japan.

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http://dx.doi.org/10.1161/CIRCHEARTFAILURE.118.005496DOI Listing
December 2018
3 Reads

Etiology and prognosis of acute respiratory failure in patients with primary malignant brain tumors admitted to the intensive care unit.

J Neurooncol 2019 Mar 7;142(1):139-148. Epub 2018 Dec 7.

Sorbonne Universités, UPMC Univ Paris 06, INSERM, UMRS_1158 Neurophysiologie respiratoire expérimentale et clinique, Paris, France.

Purpose: Acute respiratory failure (ARF) is common and potentially fatal in patients with primary malignant brain tumors (PMBT). However, few data are available regarding its precipitating factors and prognosis. We sought to: (1) compare the causes of ARF and the outcome between patients with PMBT and patients with other peripheral solid tumors (PST), (2) identify the factors influencing ICU survival in PMBT patients. Read More

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http://dx.doi.org/10.1007/s11060-018-03074-yDOI Listing
March 2019
4 Reads

Polish recommendations for lung ultrasound in internal medicine (POLLUS-IM).

J Ultrason 2018 ;18(74):198-206

Department of Econometrics at the Faculty of Management, University of Gdansk, Gdansk, Poland.

The aim of this study was to establish recommendations for the use of lung ultrasound in internal medicine, based on reliable data and expert opinions. Methods: The bibliography from the databases (Pubmed, Medline, OVID, Embase) has been fully reviewed up to August 2017. Members of the expert group assessed the credibility of the literature data. Read More

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http://jultrason.pl/index.php/issues/volume-18-no-74/polish-
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http://dx.doi.org/10.15557/JoU.2018.0030DOI Listing
January 2018
20 Reads

Cardiogenic Shock after Nifedipine Administration in a Pregnant Patient: A Case Report and Review of the Literature.

J Transl Int Med 2018 09 9;6(3):152-156. Epub 2018 Oct 9.

Department of Intensive Care Medicine, Brugmann University Hospital, Université Libre de Bruxelles, Brussels, Belgium.

We present a case of a 21-year-old Caucasian woman at 27 weeks of pregnancy who was admitted to the obstetric department for pre-term labor. She received 10 mg of nifedipine 4 times in 1 h, according to the internal protocol. Shortly after, she brutally deteriorated with pulmonary edema and hypoxemia requiring transfer to the intensive care unit (ICU) for mechanical ventilation. Read More

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http://content.sciendo.com/view/journals/jtim/6/3/article-p1
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http://dx.doi.org/10.2478/jtim-2018-0029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6231299PMC
September 2018
18 Reads

[Use of noninvasive ventilation in critically ill patients].

Orv Hetil 2018 11;159(45):1831-1837

Aneszteziológiai és Intenzív Terápiás Klinika, Semmelweis Egyetem, Általános Orvostudományi Kar Budapest, Üllői út 78., 1085.

Introduction: The use of noninvasive ventilation has increased worldwide. Its mortality reducing benefit has been shown in several different conditions compared to invasive ventilation. Common counterarguments against the technique are its increased technical and caregiver requirements and increased mortality associated with treatment failure. Read More

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http://dx.doi.org/10.1556/650.2018.31052DOI Listing
November 2018
3 Reads

Acute severe mitral regurgitation with cardiogenic shock following balloon mitral valvuloplasty: echocardiographic findings and outcomes following surgery.

Cardiovasc Interv Ther 2018 Nov 9. Epub 2018 Nov 9.

Department of Cardiology, JIPMER, Puducherry, 605006, India.

Acute severe mitral regurgitation (MR) is the commonest indication for emergency surgery following a balloon mitral valvuloplasty (BMV). It results in hemodynamic compromise with cardiogenic shock and or acute pulmonary edema. These patients deteriorate fast and often require respiratory and critical care support, followed by urgent mitral valve replacement (MVR). Read More

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http://link.springer.com/10.1007/s12928-018-0555-4
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http://dx.doi.org/10.1007/s12928-018-0555-4DOI Listing
November 2018
16 Reads

A case of pulmonary edema: The critical role of lung-heart integrated ultrasound examination.

Monaldi Arch Chest Dis 2018 10 1;88(3):982. Epub 2018 Oct 1.

CTO Hospital, Emergency Department.

Cardiogenic pulmonary edema is a common presentation of acute heart failure normally treated with continuous positive airway pressure (CPAP), diuretics and nitrates. This therapy is contraindicated in case of cardiac tamponade. We describe a case of pulmonary edema due to cardiac tamponade in which integrated lung-heart ultrasound examination allowed prompt diagnosis and pericardiocentesis before administration of CPAP thus avoiding circulatory collapse. Read More

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http://dx.doi.org/10.4081/monaldi.2018.982DOI Listing
October 2018
5 Reads

Non-invasive ventilation in cardiogenic pulmonary edema.

Ann Transl Med 2018 Sep;6(18):355

Department of Anesthesia and Intensive Care, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy.

Cardiogenic pulmonary edema (CPE) is among the most common causes of acute respiratory failure (ARF) in the acute care setting and often requires ventilatory assistance. In patients with ARF due to CPE, use of non-invasive positive airway pressure can decrease the systemic venous return and the left ventricular (LV) afterload, thus reducing LV filling pressure and limiting pulmonary edema. In these patients, either non-invasive ventilation (NIV) or continuous positive airway pressure (CPAP) can improve vital signs and physiological parameters, decreasing the need for endotracheal intubation (ETI) and hospital mortality when compared to conventional oxygen therapy. Read More

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http://atm.amegroups.com/article/view/19394/20876
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http://dx.doi.org/10.21037/atm.2018.04.39DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186545PMC
September 2018
12 Reads

The neutrophil chemoattractant peptide proline-glycine-proline is associated with acute respiratory distress syndrome.

Am J Physiol Lung Cell Mol Physiol 2018 Nov 9;315(5):L653-L661. Epub 2018 Aug 9.

Division of Pulmonary, Allergy and Critical Care Medicine, University of Alabama at Birmingham , Birmingham, Alabama.

Acute respiratory distress syndrome (ARDS) is characterized by unrelenting polymorphonuclear neutrophil (PMN) inflammation and vascular permeability. The matrikine proline-glycine-proline (PGP) and acetylated PGP (Ac-PGP) have been shown to induce PMN inflammation and endothelial permeability in vitro and in vivo. In this study, we investigated the presence and role of airway PGP peptides in acute lung injury (ALI)/ARDS. Read More

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https://www.physiology.org/doi/10.1152/ajplung.00308.2017
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http://dx.doi.org/10.1152/ajplung.00308.2017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295514PMC
November 2018
11 Reads

Acute pancreatitis-induced takotsubo cardiomyopathy and cardiogenic shock treated with a percutaneous left ventricular assist device.

BMJ Case Rep 2018 Oct 12;2018. Epub 2018 Oct 12.

Department of Critical Care Medicine, Mayo Clinic's Campus in Florida, Jacksonville, Florida, USA.

A 63-year-old man was admitted for severe acute pancreatitis. On day 3 of hospitalisation, he developed shortness of breath and acute pulmonary oedema. Echocardiogram revealed global hypokinesis with a left ventricular ejection fraction of 20%, and he was diagnosed with takotsubo cardiomyopathy. Read More

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http://dx.doi.org/10.1136/bcr-2018-225877DOI Listing
October 2018
24 Reads

Unilateral cardiogenic pulmonary edema.

J Cardiol Cases 2018 Mar 27;17(3):85-88. Epub 2017 Nov 27.

The Department of Medicine & Cardiology, Chikamori Hospital, Kochi, Japan.

A 45-year-old man presented with fatigue for the previous two days. Because of severe hypoxemia and chest radiograph showing severe consolidation only in the right lung field, he was admitted to a near-by district hospital under the diagnosis of acute pneumonia. Since his respiratory condition rapidly deteriorated, he was transferred to our hospital. Read More

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http://dx.doi.org/10.1016/j.jccase.2017.10.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6149651PMC
March 2018
6 Reads

Positive Pressure Ventilation in the Cardiac Intensive Care Unit.

J Am Coll Cardiol 2018 Sep;72(13):1532-1553

Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts. Electronic address:

Contemporary cardiac intensive care units (CICUs) provide care for an aging and increasingly complex patient population. The medical complexity of this population is partly driven by an increased proportion of patients with respiratory failure needing noninvasive or invasive positive pressure ventilation (PPV). PPV often plays an important role in the management of patients with cardiogenic pulmonary edema, cardiogenic shock, or cardiac arrest, and those undergoing mechanical circulatory support. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S07351097183572
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http://dx.doi.org/10.1016/j.jacc.2018.06.074DOI Listing
September 2018
13 Reads
16.503 Impact Factor

Oral Dipyridamole-Associated Circulatory Collapse.

J Stroke Cerebrovasc Dis 2018 Dec 2;27(12):3460-3462. Epub 2018 Sep 2.

Department of Surgery, Division of Vascular Surgery, Tampere University Hospital, Tampere, Finland.

Extended-release dipyridamole plus aspirin is widely used for secondary prevention of ischemic stroke, although the molecular pharmacodynamics of dipyridamole are not completely determined. Adverse effects of fixed-dose combination of aspirin and dipyridamole include headache, bleeding, and gastrointestinal events. Previously, intravenous infusion of dipyridamole in cardiac stress testing has been associated with cardiogenic shock and pulmonary edema. Read More

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http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2018.08.009DOI Listing
December 2018
4 Reads

Evaluation of thrombotic left main coronary artery occlusions; old problem, different treatment approaches.

Authors:
Murat Akcay

Indian Heart J 2018 Jul - Aug;70(4):573-574. Epub 2017 Sep 14.

Department of Cardiology, Faculty of Medicine, Ondokuz Mayis University, Samsun, Turkey. Electronic address:

Thrombotic left main coronary artery (LMCA) occlusions usually manifest as acute coronary syndrome (ACS) with cardiogenic shock, acute pulmonary edema, cardiac arrest, fatal arrhythmias or sudden cardiac death. There is no clinically predictor for LMCA thrombosis and no consensus regarding the optimal treatment. In the current literature, treatment options include emergency coronary artery bypass grafting (CABG), stent implantation, intracoronary thrombolysis, anticoagulation with heparin or glycoprotein IIb/IIIa inhibitors, thrombus aspiration as reperfusion strategies. Read More

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http://dx.doi.org/10.1016/j.ihj.2017.09.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117801PMC
October 2018
4 Reads

Pressure support ventilation vs continuous positive airway pressure for treating of acute cardiogenic pulmonary edema. Comment.

Respir Physiol Neurobiol 2019 01 27;259:176-177. Epub 2018 Aug 27.

School of Medicine, Universidad San Francisco de Quito, Quito, Ecuador. Electronic address:

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http://dx.doi.org/10.1016/j.resp.2018.08.004DOI Listing
January 2019
3 Reads

Hypocapnia and mental stress can trigger vicious circles in critically ill patients due to energy imbalance: a hypothesis presented through cardiogenic pulmonary oedema.

Authors:
Andras Sikter

Neuropsychopharmacol Hung 2018 Jun;20(2):65-74

Municipal Clinic of Szentendre, Internal Medicine, Szentendre, Hungary.

The pathophysiologic significance of hypocapnia is strongly underestimated both in functional and organic diseases. Alterations of carbon dioxide levels immediately appear in the cytoplasm, causing abrupt pH changes. Compensatory mechanisms develop with latency, so intracellular alkalosis or acidosis can affect metabolism for hours/days. Read More

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June 2018
3 Reads

Successful multidisciplinary treatment of uterine serous carcinoma in a patient who had previously undergone renal transplantation.

Taiwan J Obstet Gynecol 2018 Aug;57(4):601-604

Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital, Linkou Medical Center, Taoyuan, Taiwan; Gynecologic Cancer Research Center, Chang Gung Memorial Hospital, Taiwan. Electronic address:

Objective: Renal transplantation is a risk factor for premalignant and malignant changes of the endometrium. Thus, prompt and aggressive treatment of postoperative complications remains a major issue. We report the case of an asymptomatic postmenopausal woman with a history of renal transplantation who underwent surgery for uterine serous carcinoma (USC). Read More

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http://dx.doi.org/10.1016/j.tjog.2018.06.023DOI Listing
August 2018
3 Reads

Radiologic evaluation of pulmonary injury following carmustine- and cyclophosphamide-based preparative regimen for autologous peripheral blood stem cell transplantation in children.

Pediatr Radiol 2018 12 18;48(13):1875-1883. Epub 2018 Aug 18.

Department of Radiology, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, Seoul, 03080, South Korea.

Background: Toxicity of carmustine and cyclophosphamide can cause pulmonary injury after hematopoietic stem cell transplantation.

Objective: To evaluate the radiologic findings of pulmonary injuries following carmustine- and cyclophosphamide-based preparative regimens in children.

Materials And Methods: From 2010 to 2014, 35 children received carmustine- and cyclophosphamide-based preparative regimens. Read More

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http://dx.doi.org/10.1007/s00247-018-4223-8DOI Listing
December 2018
4 Reads

Platelet to Lymphocyte Ratio on Admission and Prognosis in Patients with Acute Cardiogenic Pulmonary Edema.

J Emerg Med 2018 10 14;55(4):465-471. Epub 2018 Aug 14.

Department of Cardiology, Numune Education and Training Hospital, Ankara, Turkey.

Background: Acute heart failure is a heterogenous syndrome defined by a number of factors, such as its physiopathology, clinical picture, time of onset, and relation to acute coronary syndrome. Acute cardiogenic pulmonary edema (ACPE) constitutes approximately 10-20% of acute heart failure syndromes, and it is the most dramatic symptom of left heart failure. Platelet to lymphocyte ratio (PLR) is a relatively novel inflammatory marker that can be utilized for prognosis in various disease processes. Read More

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http://dx.doi.org/10.1016/j.jemermed.2018.06.021DOI Listing
October 2018
41 Reads

Left ventricular unloading during veno-arterial ECMO: a review of percutaneous and surgical unloading interventions.

Perfusion 2019 Mar 16;34(2):98-105. Epub 2018 Aug 16.

4 ECMO Department, Karolinska University Hospital, Stockholm, Sweden.

Short-term mechanical support by veno-arterial extracorporeal membrane oxygenation (VA ECMO) is more and more applied in patients with severe cardiogenic shock. A major shortcoming of VA ECMO is its variable, but inherent increase of left ventricular (LV) mechanical load, which may aggravate pulmonary edema and hamper cardiac recovery. In order to mitigate these negative sequelae of VA ECMO, different adjunct LV unloading interventions have gained a broad interest in recent years. Read More

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http://dx.doi.org/10.1177/0267659118794112DOI Listing
March 2019
25 Reads

Non-Invasive Mechanical Ventilation Versus Continuous Positive Airway Pressure in Cardiogenic Pulmonary Edema in an Intensive Care Unit.

Arch Bronconeumol 2019 Jan 11;55(1):63-64. Epub 2018 Aug 11.

Servicio de Medicina Intensiva, Hospital General Universitario de Castellón, Castellón de la Plana, Castellón, España. Electronic address:

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http://dx.doi.org/10.1016/j.arbres.2018.07.007DOI Listing
January 2019
4 Reads

Unilateral pulmonary edema: a case report and review of the literature.

J Med Case Rep 2018 Aug 14;12(1):219. Epub 2018 Aug 14.

Teaching Hospital, Peradeniya, Sri Lanka.

Background: Unilateral pulmonary edema is an uncommon condition and is a rare clinical entity that is often misdiagnosed at the initial stages. In a majority of patients it occurs in the upper lobe of the right lung. There are many causes of unilateral pulmonary edema, but the commonest is the presence of a grade 3 mitral regurgitation. Read More

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http://dx.doi.org/10.1186/s13256-018-1739-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090641PMC
August 2018
24 Reads

The neutrophil chemoattractant peptide proline-glycine-proline is associated with acute respiratory distress syndrome.

Am J Physiol Lung Cell Mol Physiol 2018 Nov 9;315(5):L653-L661. Epub 2018 Aug 9.

Division of Pulmonary, Allergy and Critical Care Medicine, University of Alabama at Birmingham , Birmingham, Alabama.

Acute respiratory distress syndrome (ARDS) is characterized by unrelenting polymorphonuclear neutrophil (PMN) inflammation and vascular permeability. The matrikine proline-glycine-proline (PGP) and acetylated PGP (Ac-PGP) have been shown to induce PMN inflammation and endothelial permeability in vitro and in vivo. In this study, we investigated the presence and role of airway PGP peptides in acute lung injury (ALI)/ARDS. Read More

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http://dx.doi.org/10.1152/ajplung.00308.2017DOI Listing
November 2018
13 Reads

Prehospital non-invasive ventilation in acute respiratory failure is justified even if the distance to hospital is short.

Am J Emerg Med 2018 Jul 2. Epub 2018 Jul 2.

Department of Anesthesiology, Intensive Care Medicine, Emergency Medicine and Pain Therapy, Asklepios Klinikum Harburg, Eißendorfer Pferdeweg 52, 21075 Hamburg, Germany. Electronic address:

Aims: Evaluation of the efficacy of prehospital non-invasive ventilation (NIV) in patients with acute exacerbation of chronic obstructive pulmonary disease (COPD) and cardiogenic pulmonary edema (CPE).

Material And Methods: Consecutive patients who were prehospitally treated by Emergency Physicians using NIV were prospectively included. A step-by-step approach escalating NIV-application from continuous positive airway pressure (CPAP) to continuous positive airway pressure supplemented by pressure support (CPAP-ASB) and finally bilevel inspiratory positive airway pressure (BIPAP) was used. Read More

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http://dx.doi.org/10.1016/j.ajem.2018.07.001DOI Listing
July 2018
18 Reads

ARDS Cannot Be Accurately Differentiated From Cardiogenic Pulmonary Edema Without Systematic Tissue Doppler Echocardiography.

Chest 2018 Jul;154(1):226-227

Department of Cardiology, Azienda Sanitaria Provinciale di Trapani, Trapani, Italy.

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http://dx.doi.org/10.1016/j.chest.2018.03.036DOI Listing
July 2018
3 Reads
7.483 Impact Factor