30,388 results match your criteria Pulmonary Disease and Pregnancy


Non-pulmonary complications after lung transplantation: part II.

Indian J Thorac Cardiovasc Surg 2022 Jul 12;38(Suppl 2):290-299. Epub 2021 Oct 12.

Lung Transplant Program, University of Texas Southwestern Medical Center, 5939 Harry Hines Blvd. Suite 603, Dallas, TX 75235-8550 USA.

Lung transplantation (LT) is a viable therapeutic option in the treatment of advanced lung disease. With improvements in post-transplant survival, complications involving different organ systems after LT are increasingly seen. While non-infectious, extrapulmonary complications after LT are not frequently responsible for early post-transplant mortality, they significantly impact the quality of life and long-term survival. Read More

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Impact of hypertensive disorders of pregnancy on respiratory outcomes in extremely and very preterm infants: A population-based study in Japan.

Pregnancy Hypertens 2022 Jun 17;29:54-60. Epub 2022 Jun 17.

Department of Obstetrics and Gynecology, Nagoya University Graduate School of Medicine, Nagoya, Japan; Division of Perinatology, Center for Maternal-Neonatal Care, Nagoya University Hospital, Nagoya, Japan.

Objectives: We aimed to evaluate the impact of hypertensive disorders of pregnancy (HDP) on short- and medium-term respiratory outcomes in extremely and very preterm infants using the Neonatal Research Network of Japan database.

Study Design: This was a population-based retrospective study of preterm infants weighing ≤ 1500 g born between 22 and 31 weeks of gestation between 2003 and 2017. After 1:1 stratification matching by four factors (maternal age, gestational age, parity, and year of delivery), a total of 5137 infants in each group (HDP and non-HDP groups) were selected. Read More

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Editorial: Coronavirus Disease (COVID-19): Pathophysiology, Epidemiology, Clinical Management and Public Health Response, Volume II.

Front Public Health 2022 7;10:913507. Epub 2022 Jun 7.

School of Biomedical Sciences and Pharmacy, College of Health, Medicine and Wellbeing, University of Newcastle, Newcastle, NSW, Australia.

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SARS-CoV-2, Placental Histopathology, Gravity of Infection and Immunopathology: Is There an Association?

Viruses 2022 Jun 18;14(6). Epub 2022 Jun 18.

Section of Pathology, Department of Emergency and Organ Transplantation (DETO), University of Bari "Aldo Moro", 70124 Bari, Italy.

(1) Background: As the pandemic months progress, more and more evidence shows that the placenta acts as a "barrier" to SARS-CoV-2, although rare cases of vertical transmission have been described. (2) Methods: In an attempt to investigate whether the symptoms' severity was related to different placental histological characteristics and the immune microenvironment, we subdivided 29 placentas from 29 mothers positive for SARS-CoV-2 into two groups, depending on the symptomatology (moderate/severe vs. asymptomatic/mild), performing immunohistochemical investigations for CD4 + and CD8 + T lymphocytes, as well as for CD68 + macrophage. Read More

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Immune System and Psychological State of Pregnant Women during COVID-19 Pandemic: Are Micronutrients Able to Support Pregnancy?

Nutrients 2022 Jun 18;14(12). Epub 2022 Jun 18.

Department of Biomedical and Dental Science and Morphofunctional Imaging, University of Messina, 98125 Messina, Italy.

The immune system is highly dynamic and susceptible to many alterations throughout pregnancy. Since December 2019, a pandemic caused by coronavirus disease 19 (COVID-19) has swept the globe. To contain the spread of COVID-19, immediate measures such as quarantine and isolation were implemented. Read More

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Proteomic Analysis of Human Milk Reveals Nutritional and Immune Benefits in the Colostrum from Mothers with COVID-19.

Nutrients 2022 Jun 17;14(12). Epub 2022 Jun 17.

Institute for Cell Analysis, Shenzhen Bay Laboratory, Shenzhen 518132, China.

Despite the well-known benefits of breastfeeding and the World Health Organization's breastfeeding recommendations for COVID-19 infected mothers, whether these mothers should be encouraged to breastfeed is under debate due to concern about the risk of virus transmission and lack of evidence of breastmilk's protective effects against the virus. Here, we provide a molecular basis for the breastfeeding recommendation through mass spectrometry (MS)-based proteomics and glycosylation analysis of immune-related proteins in both colostrum and mature breastmilk collected from COVID-19 patients and healthy donors. The total protein amounts in the COVID-19 colostrum group were significantly higher than in the control group. Read More

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Determinants of Place of Delivery during the COVID-19 Pandemic-Internet Survey in Polish Pregnant Women.

Medicina (Kaunas) 2022 Jun 20;58(6). Epub 2022 Jun 20.

Department of Emergency Medical Service, Wroclaw Medical University, 50-367 Wroclaw, Poland.

COVID-19 is a pandemic disease, and its unpredictable outcome makes it particularly dangerous, especially for pregnant women. One of the decisions they have to make is where they will give birth. This study aimed to determine the factors influencing the choice of place of delivery and the impact of the COVID 19 pandemic on these factors. Read More

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The Influence of Maternal Factors on Neonatal Intensive Care Unit Admission and In-Hospital Mortality in Premature Newborns from Western Romania: A Population-Based Study.

Medicina (Kaunas) 2022 May 26;58(6). Epub 2022 May 26.

Department of Obstetrics and Gynecology, "Victor Babes" University of Medicine and Pharmacy Timisoara, 300041 Timisoara, Romania.

: Neonatal mortality is a global public health issue, disproportionately affecting low- and middle-income nations. Although Romania is a high-income nation, according to the European Union's most recent demographic data, it had the second-highest infant death rate in 2019. Although significant progress has been made in the last three decades in lowering newborn mortality, more initiatives to accelerate progress are required to meet the 2030 Sustainable Development Goals (SDG) objective. Read More

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RAGE against the Machine: Can Increasing Our Understanding of RAGE Help Us to Battle SARS-CoV-2 Infection in Pregnancy?

Int J Mol Sci 2022 Jun 7;23(12). Epub 2022 Jun 7.

School of Natural Sciences and Mathematics, Chaminade University of Honolulu, Honolulu, HI 96816, USA.

The receptor of advanced glycation end products (RAGE) is a receptor that is thought to be a key driver of inflammation in pregnancy, SARS-CoV-2, and also in the comorbidities that are known to aggravate these afflictions. In addition to this, vulnerable populations are particularly susceptible to the negative health outcomes when these afflictions are experienced in concert. RAGE binds a number of ligands produced by tissue damage and cellular stress, and its activation triggers the proinflammatory transcription factor Nuclear Factor Kappa B (NF-κB), with the subsequent generation of key proinflammatory cytokines. Read More

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Health Promotion Behaviors of Pregnant Couples in the COVID-19 Pandemic: Actor-Partner Interdependence Model.

Int J Environ Res Public Health 2022 Jun 19;19(12). Epub 2022 Jun 19.

Red Cross College of Nursing, Chung-Ang University, Seoul 06974, Korea.

Pregnancy during the pandemic may be a stressful life event. This cross-sectional study aimed to identify the actor and partner effects of the fear of COVID-19, depression, posttraumatic growth, and marital adjustment on the health promotion behaviors of pregnant couples during the COVID-19 pandemic in Korea. Data were collected from 123 pregnant couples using a structured questionnaire. Read More

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Experiences of Birth during COVID-19 Pandemic in Italy and Spain: A Thematic Analysis.

Int J Environ Res Public Health 2022 Jun 18;19(12). Epub 2022 Jun 18.

Department of Nursing, Universitat Jaume I, Avenida de Vicent Sos Baynat, s/n, 12071 Castellón de la Plana, Spain.

Becoming parents during the pandemic of coronavirus disease 2019 (COVID-19) has been a challenge. The purpose of this study was to describe the impact of the pandemic on new and expectant parents in both Italy and Spain. A descriptive qualitative study was carried out by collecting social media posts written by parents between March 2020 and April 2021. Read More

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Seroprevalence of SARS-CoV-2 Antibodies in Africa: A Systematic Review and Meta-Analysis.

Int J Environ Res Public Health 2022 Jun 14;19(12). Epub 2022 Jun 14.

Department of Medical Microbiology and Parasitology, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian 16150, Malaysia.

A reliable estimate of SARS-CoV-2-specific antibodies is increasingly important to track the spread of infection and define the true burden of the ongoing COVID-19 pandemic. A systematic review and a meta-analysis were conducted with the objective of estimating the seroprevalence of SARS-CoV-2 infection in Africa. A systematic search of the PubMed, Scopus, Web of Science and Google Scholar electronic databases was conducted. Read More

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Risk Measurement of Perinatal and Neonatal Morbidity Characteristics and Applicability of GAIA Case Definitions: Results and Lessons Learnt of a Hospital-Based Prospective Cohort Study in the Valencia Region (2019-2020).

Int J Environ Res Public Health 2022 Jun 10;19(12). Epub 2022 Jun 10.

Vaccines Research Department, Fundación Para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (Fisabio), Av. de Catalunya, 21, 46020 Valencia, Spain.

Post-marketing safety surveillance of new vaccines aimed to be administered during pregnancy is crucial to orchestrate efficient adverse events evaluation. This is of special relevance in the current landscape of new vaccines being introduced in the pregnant women population, and particularly due to the recent administration of COVID-19 vaccines in pregnant women. This multi-center prospective cohort study, nested within the WHO-Global Vaccine Safety-MCC study, involved two hospitals in the Valencia region. Read More

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Predictors of Vaccine Hesitancy among Health Care Workers during the COVID-19 Pandemic.

Int J Environ Res Public Health 2022 Jun 10;19(12). Epub 2022 Jun 10.

Trauma Research Consortium, Baylor Scott & White Research Institute, Department of Trauma, Critical Care and Acute Care Surgery, Baylor University Medical Center, Dallas, TX 75246, USA.

Most studies of COVID-19 vaccine hesitancy among health care workers (HCWs) have been descriptive, few have tested models to predict hesitancy, and none have examined the possible relationship between HCWs' distress and vaccine hesitancy. This study examined predictors of COVID-19 vaccine hesitancy, including HCWs' distress after taking into account HCW sex, doctoral-level status, race, age, and exposure to COVID-19. Further, it examined specific reasons HCWs endorsed for their hesitancy. Read More

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Cascading Risks for Preventable Infectious Diseases in Children and Adolescents during the 2022 Invasion of Ukraine.

Int J Environ Res Public Health 2022 Jun 8;19(12). Epub 2022 Jun 8.

Center for Disaster & Extreme Event Preparedness (DEEP Center), P3H: Protect & Promote Population Health in Complex Crises, Department of Public Health Sciences, University of Miami Miller School of Medicine, Don Soffer Clinical Research Center Room 1507, 1120 NW 14 St., Miami, FL 33136, USA.

Russia's military incursion into Ukraine triggered the mass displacement of two-thirds of Ukrainian children and adolescents, creating a cascade of population health consequences and producing extraordinary challenges for monitoring and controlling preventable pediatric infectious diseases. From the onset of the war, infectious disease surveillance and healthcare systems were severely disrupted. Prior to the reestablishment of dependable infectious disease surveillance systems, and during the early months of the conflict, our international team of pediatricians, infectious disease specialists, and population health scientists assessed the health implications for child and adolescent populations. Read More

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Transcriptional Profiling of Insulin-like Growth Factor Signaling Components in Embryonic Lung Development and Idiopathic Pulmonary Fibrosis.

Cells 2022 Jun 20;11(12). Epub 2022 Jun 20.

Department of Medicine II, Internal Medicine, Pulmonary and Critical Care, Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Justus-Liebig University Giessen, 35392 Giessen, Germany.

Insulin-like growth factor (IGF) signaling controls the development and growth of many organs, including the lung. Loss of function of or its receptor impairs lung development and leads to neonatal respiratory distress in mice. Although many components of the IGF signaling pathway have shown to be dysregulated in idiopathic pulmonary fibrosis (IPF), the expression pattern of such components in different cellular compartments of the developing and/or fibrotic lung has been elusive. Read More

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Obstetric and perinatal outcomes in parturients with active SARS-CoV-2 infection during labor and delivery: a retrospective cohort study.

BMC Pregnancy Childbirth 2022 Jun 23;22(1):511. Epub 2022 Jun 23.

Helen Schneider Hospital for Women, Rabin Medical Center - Beilinson Hospital, 39 Jabotinsky St., Petach Tikva, Israel.

Background: The COVID-19 pandemic is an ongoing global healthcare crisis that negatively affects pregnant women. Although patients with an acute infection during pregnancy have been widely studied, information regarding labor and delivery while infected is sparse. The aim of the study was to ascertain maternal, obstetrical, and perinatal outcomes of women who gave birth while infected with SARS-CoV-2. Read More

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Influence of Timing of Antenatal Corticosteroid Administration on Morbidity of Preterm Neonates.

In Vivo 2022 Jul-Aug;36(4):1777-1784

Department of Gynecology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.

Background/aim: We investigated the impact of the timing of antenatal corticosteroid (ACS) administration on the clinical outcome of preterm infants.

Patients And Methods: Two hundred and fifty-five preterm infants between 28+0 and 34+0 weeks of gestation were retrospectively assigned to one of two groups: In the first group, ACS was given within 7 days before birth; the second group, did not receive ACS during that period. The primary outcome parameter was respiratory failure (defined by need for continuous positive airway pressure or mechanical ventilation) due to grade 1-4 respiratory distress syndrome (RDS). Read More

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To Fight or to Flee? A Systematic Review of Ectopic Pregnancy Management and Complications During the Covid-19 Pandemic.

In Vivo 2022 Jul-Aug;36(4):1570-1579

Whipps Cross University Hospital, Barts Health NHS Trust, London, U.K.

Background/aim: During the COVID-19 pandemic, concerns regarding theoretical risks of surgery contributed to changes in clinical management to prevent contamination. We looked at the effect the pandemic had on the management of ectopic pregnancy. Our review compares published data on pre-COVID to COVID management of ectopic pregnancies and evaluates the differences where Early Pregnancy Unit (EPU) structures exist. Read More

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Hospitalization and Emergency Department Encounters for COVID-19 After Paxlovid Treatment - California, December 2021-May 2022.

MMWR Morb Mortal Wkly Rep 2022 Jun 24;71(25):830-833. Epub 2022 Jun 24.

Nirmatrelvir/ritonavir (Paxlovid) is a combination protease inhibitor that blocks replication of SARS-CoV-2 (the virus that causes COVID-19) and has been shown to reduce the risk for hospitalization and death among patients with mild to moderate COVID-19 who are at risk for progression to severe disease* (1). In December 2021, the Food and Drug Administration (FDA) issued an Emergency Use Authorization (EUA) for early treatment with Paxlovid among persons with mild to moderate cases of COVID-19 who are at high risk for progression to severe disease (2). FDA and a small number of published case reports have documented recurrence of COVID-19 symptoms or a positive viral test result (COVID-19 rebound) 2-8 days after recovery or a negative SARS-CoV-2 test result among patients treated with Paxlovid (3-7); however, large-scale studies investigating severe illness after Paxlovid treatment are limited. Read More

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Racial and Ethnic Disparities in Postpartum Care in the Greater Boston Area During the COVID-19 Pandemic.

JAMA Netw Open 2022 Jun 1;5(6):e2216355. Epub 2022 Jun 1.

Center for Anesthesia Innovation and Quality, Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Boston, Massachusetts.

Importance: Racial and ethnic disparities in postpartum care access have been well identified in the United States. Such disparities could be exacerbated by the COVID-19 pandemic because of amplified economic distress and compromised social capital among pregnant women who belong to racial or ethnic minority groups.

Objective: To examine whether the COVID-19 pandemic is associated with an increase in the existing racial and ethnic disparity in postpartum care access. Read More

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Pregnancy in Pulmonary Arterial Hypertension: A Multidisciplinary Approach.

J Cardiovasc Dev Dis 2022 Jun 18;9(6). Epub 2022 Jun 18.

Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY 10467, USA.

Pulmonary arterial hypertension (PAH), a female predominant disease, carries a high maternal and fetal mortality in pregnancy despite improved insight and the development of novel therapies. The high risk is attributed to the adaptive changes that take place to promote healthy fetal development during pregnancy, which can adversely affect the already compromised right ventricle in patients with PAH. While in the prior era emphasis was placed on termination of pregnancy, here we will illustrate through a multidisciplinary approach and meticulous planning at an expert center, these high-risk women can undergo successful childbirth. Read More

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Prevalence, characteristics, and predictors of healthcare workers with COVID-19 infection in an urban district in Malaysia.

Pan Afr Med J 2022 24;41:243. Epub 2022 Mar 24.

Department of Community Health, Faculty of Medicine, Universiti Kebangsaan Malaysia, Jalan Yaakob Latif, Cheras, Kuala Lumpur, 56000, Malaysia.

Introduction: healthcare workers (HCWs) are at high risk of acquiring COVID-19 occupational transmission and subsequently, exposing patients and others. This study aimed to determine the prevalence and examine the characteristics and predictors of HCWs with COVID-19 infection in a Malaysian district.

Methods: this is a cross-sectional study of HCWs working at Cheras District Health Office, with COVID-19 infection from 1 January to 31 October 2021. Read More

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Instituting a Curriculum for Cardio-Obstetrics Subspecialty Fellowship Training.

Methodist Debakey Cardiovasc J 2022 3;18(3):14-23. Epub 2022 Jun 3.

Johns Hopkins University School of Medicine, Baltimore, Maryland, US.

Maternal mortality is rising in the United States, and cardiovascular disease is the leading cause. Adverse pregnancy outcomes such as preeclampsia and gestational diabetes heighten the risk of cardiovascular complications during pregnancy and the peripartum period and are associated with long-term cardiovascular risks. The field of cardio-obstetrics is a subspecialty within adult cardiology that focuses on the management of women with or at high risk for heart disease who are considering pregnancy or have become pregnant. Read More

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Prenatal diagnosis of a coronary-to-pulmonary artery fistula in a fetus with pulmonary atresia and ventricular septal defect.

BMJ Case Rep 2022 Jun 22;15(6). Epub 2022 Jun 22.

Department of Pediatrics, School of Medicine Graduate School of Medicine, Osaka University, Suita, Osaka, Japan.

Pulmonary atresia and ventricular septal defect (PA/VSD) demonstrate a wide variety of pulmonary and coronary artery abnormalities; additionally, coronary-to-pulmonary artery fistula (CPAF) is a rare manifestation of PA/VSD and is seldom detected during pregnancy. In this report, we present a case of prenatal diagnosis of CPAF in PA/VSD and impactful images in a neonate, which were obtained using fetal echocardiography and postnatal electrocardiography-gated 320-row CT. Prenatal diagnosis of CPAF can facilitate the provision of better therapeutic strategies after birth. Read More

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Hypertensive disorders of pregnant women with heart disease: the ESC EORP ROPAC Registry.

Eur Heart J 2022 Jun 21. Epub 2022 Jun 21.

Department of Cardiology, Erasmus MC, University Medical Center Rotterdam, Rg-435 - P.O. Box: 2040, Rotterdam, 3000 CA, The Netherlands.

Aims: Hypertensive disorders of pregnancy (HDP) occur in 10% of pregnancies in the general population, pre-eclampsia specifically in 3-5%. Hypertensive disorders of pregnancy may have a high prevalence in, and be poorly tolerated by, women with heart disease.

Methods And results: The prevalence and outcomes of HDP (chronic hypertension, gestational hypertension or pre-eclampsia) were assessed in the ESC EORP ROPAC (n = 5739), a worldwide prospective registry of pregnancies in women with heart disease. Read More

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Evaluating the level of patient satisfaction with telehealth antenatal care during the COVID-19 pandemic at King Abdul-Aziz Medical City, Primary Health Care Center, Specialized Polyclinic.

Womens Health (Lond) 2022 Jan-Dec;18:17455057221104659

Ministry of National Guard-Health Affairs, Jeddah, Saudi Arabia, Department of Primary Healthcare, King Abdul-Aziz Medical City (KAMC), Jeddah, Saudi Arabia.

Aim: To evaluate the client satisfaction with a phone-based antenatal care consultation and identify the associated factors during the COVID-19 pandemic at King Abdul-Aziz Medical City, Primary Health Care Center Specialized Polyclinic during 2020.

Method: The study was a cross-sectional, retrospective study conducted with pregnant women attending the maternity clinic at the Specialized Polyclinic, Primary Health Care Center at King Abdul-Aziz Medical City, Jeddah. A self-administered questionnaire was sent via a text message (short message service) to collect the data after signed written consent. Read More

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Clusters of preterm live births and respiratory distress syndrome-associated neonatal deaths: spatial distribution and cooccurrence patterns.

BMC Public Health 2022 Jun 20;22(1):1226. Epub 2022 Jun 20.

Departamento de Pediatria, Escola Paulista de Medicina - Universidade Federal de São Paulo (UNIFESP), Rua Marselhesa 630, São Paulo, Vila Clementino, 04020-060, Brazil.

Background: Prematurity and respiratory distress syndrome (RDS) are strongly associated. RDS continues to be an important contributor to neonatal mortality in low- and middle-income countries. This study aimed to identify clusters of preterm live births and RDS-associated neonatal deaths, and their cooccurrence pattern in São Paulo State, Brazil, between 2004 and 2015. Read More

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Assurer l’accès aux droits sexuels et reproductifs en temps de crise sanitaire : le Planning familial en mouvement.

Sante Publique 2022 ;33(6):1033-1037

From the beginning of the first lockdown, Le Planning Familial, a feminist and SRHR delivery service organization, with its 70 local associations have come together to pursue its mission: to ensure access to SRHR and women's rights. The quarantine has had major consequences: it has increased gender-based violence including domestic violence, it has complicated women's lives (in accessing sexual health services, late-term abortions, abortion for minors, renewal of contraception, filing of complaints, etc.) and it has limited access to information and rights (presence of antichoice movements on the internet). Read More

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Prevalence of breastfeeding and birth practices during the first wave of the COVID-19 pandemic within the Italian Baby-Friendly Hospital network. What have we learned?

Ann Ist Super Sanita 2022 Apr-Jun;58(2):100-108

Centro Prevenzione delle Malattie e Promozione della Salute, Istituto Superiore di Sanità, Rome, Italy.

Background: At the beginning of the COVID-19 pandemic, healthcare workers were faced with difficult decisions about maternity care practices. The evidence-based practices recommended by the WHO/UNICEF Baby Friendly Hospital Initiative (BFHI) were confirmed by Italian national guidance.

Aim: To describe, in a number of facilities that are part of a national Baby-Friendly network, the adherence to some steps of BFHI standards during the COVID-19 emergency. Read More

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