14,360 results match your criteria Pulmonary Artery Catheterization


Endothelial Cell-Derived SO Controls Endothelial Cell Inflammation, Smooth Muscle Cell Proliferation, and Collagen Synthesis to Inhibit Hypoxic Pulmonary Vascular Remodelling.

Oxid Med Cell Longev 2021 17;2021:5577634. Epub 2021 Apr 17.

Department of Pediatrics, Peking University First Hospital, Beijing 100034, China.

Hypoxic pulmonary vascular remodelling (PVR) is the major pathological basis of aging-related chronic obstructive pulmonary disease and obstructive sleep apnea syndrome. The pulmonary artery endothelial cell (PAEC) inflammation, and pulmonary artery smooth muscle cell (PASMC) proliferation, hypertrophy and collagen remodelling are the important pathophysiological components of PVR. Endogenous sulfur dioxide (SO) was found to be a novel gasotransmitter in the cardiovascular system with its unique biological properties. Read More

View Article and Full-Text PDF

Current Limitations of Invasive Exercise Hemodynamics for the Diagnosis of Heart Failure With Preserved Ejection Fraction.

Circ Heart Fail 2021 May 6:CIRCHEARTFAILURE120007555. Epub 2021 May 6.

Department of Cardiology, Cliniques Universitaires de Bruxelles, Hôpital Académique Erasme, Belgium (C.D., A.B., J.-L.V.).

Background: Exercise hemodynamics can differentiate heart failure with preserved ejection fraction (HFpEF) from noncardiac dyspnea. However, respiratory pressure swings may impact hemodynamic measurements, potentially leading to misdiagnosis of HFpEF. Moreover, threshold values for abnormal hemodynamic response indicative of HFpEF are not universally accepted. Read More

View Article and Full-Text PDF

Accelerated Estimation of Pulmonary Artery Stenosis Pressure Gradients with Distributed Lumped Parameter Modeling vs. 3D CFD with Instantaneous Adaptive Mesh Refinement: Experimental Validation in Swine.

Ann Biomed Eng 2021 May 4. Epub 2021 May 4.

Biomedical Engineering, University of Wisconsin, Madison, WI, USA.

Branch pulmonary artery stenosis (PAS) commonly occurs in congenital heart disease and the pressure gradient over a stenotic PA lesion is an important marker for re-intervention. Image based computational fluid dynamics (CFD) has shown promise for non-invasively estimating pressure gradients but one limitation of CFD is long simulation times. The goal of this study was to compare accelerated predictions of PAS pressure gradients from 3D CFD with instantaneous adaptive mesh refinement (AMR) versus a recently developed 0D distributed lumped parameter CFD model. Read More

View Article and Full-Text PDF

The Relationship of Pleural and Pericardial Effusion With Pulmonary Hemodynamics in Patients With Pulmonary Hypertension.

Am J Med Sci 2021 Jan 9. Epub 2021 Jan 9.

Division of Pulmonary, Critical Care, Allergy and Sleep Medicine, Medical University of South Carolina, Charleston, South Carolina, United States.

Background: The relationship between the presence of pleural and pericardial effusion in reference to hemodynamic parameters remains unclear in ambulatory patients with pulmonary hypertension (PH).

Methods: Consecutive patients who underwent right catheterization (RHC) for the evaluation of pulmonary hypertension were enrolled. Point-of- care ultrasound was performed prior to the RHC to determine the presence of pleural effusion and pericardial effusion. Read More

View Article and Full-Text PDF
January 2021

Refractory pleural effusion as a rare complication of pulmonary vascular stenosis induced by fibrosing mediastinitis: a case report and literature review.

J Int Med Res 2021 May;49(5):3000605211010073

Department of Pulmonary and Critical Care Medicine, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.

Fibrosing mediastinitis (FM) is a progressive, life-threatening disease characterized by extrinsic compression of mediastinal bronchovascular structures, and the clinical manifestations largely depend upon the affected structures. Pleural effusion is rarely reported in patients with FM. We herein describe a 70-year-old man who presented with recurrent breathlessness and refractory left pleural effusion. Read More

View Article and Full-Text PDF

CON: Pulmonary artery catheter use should be forgone in modern clinical practice.

Ann Card Anaesth 2021 Jan-Mar;24(1):8-11

Department of Anesthesia, Pain Management and Perioperative Medicine, Divisions of Cardiothoracic Anesthesia and Critical Care Anesthesiology, Henry Ford Hospital, Detroit, Michigan, USA.

The pulmonary artery catheter (PAC) and its role in the practice of modern medicine remains to be questioned and has experienced a substantial decline in its use in the most recent decades. The complications associated to its use, the lack of consistency of the interpretation provided by the PAC among clinicians, the development of new hemodynamic methods, and the deleterious cost profile associated to the PAC are some of the reasons behind the decrease in its use. Since its introduction into clinical practice, the PAC and the data obtained from its use became paramount in the management of critically ill patients as well as for the high-risk/invasive procedures. Read More

View Article and Full-Text PDF

PRO: The pulmonary artery catheter has a paramount role in current clinical practice.

Ann Card Anaesth 2021 Jan-Mar;24(1):4-7

Department of Anesthesia, Pain Management and Perioperative Medicine, Divisions of Cardiothoracic Anesthesia and Critical Care Anesthesiology, Henry Ford Hospital, Detroit, Michigan, USA.

Ever since its clinical introduction, the utilization of the pulmonary artery catheter (PAC) has been surrounded by multiple controversies, mostly related to imprecise clinical indications and the complications derived from its placement. Currently, one of the most important criticisms of the PAC is the ambiguity in the interpretation of its hemodynamic measurements and therefore, in the translation of this data into specific therapeutic interventions. The popularity of the PAC stems from the fact that it provides hemodynamic data that cannot be obtained from clinical examination. Read More

View Article and Full-Text PDF

Lung cancer with partial anomalous pulmonary venous connection in a different lobe: a case report.

J Cardiothorac Surg 2021 May 1;16(1):122. Epub 2021 May 1.

Department of General Thoracic Surgery, Nihonkai General Hospital, 30 Akiho-cho, Sakata, Yamagata, Japan.

Background: Anomalous pulmonary venous connection (APVC) is a congenital malformation in which the pulmonary veins connect to the systemic venous system but not to the left atrium. APVC can be classified as total or partial (PAPVC). PAPVC is rare among surgical patients with lung cancer, and most cases are detected incidentally during surgery. Read More

View Article and Full-Text PDF

Safety and Feasibility of MitraClip Implantation in Patients with Acute Mitral Regurgitation after Recent Myocardial Infarction and Severe Left Ventricle Dysfunction.

J Clin Med 2021 Apr 22;10(9). Epub 2021 Apr 22.

Department of Cardiology, Joan XXIII University Hospital, 43005 Tarragona, Spain.

Patients with severe mitral regurgitation (MR) after myocardial infarction (MI) have an increased risk of mortality. Transcatheter mitral valve repair may therefore be a suitable therapy. However, data on clinical outcomes of patients in an acute setting are scarce, especially those with reduced left ventricle (LV) dysfunction. Read More

View Article and Full-Text PDF

Total Transcatheter Stage 1: A Word of Caution.

Pediatr Cardiol 2021 Apr 29. Epub 2021 Apr 29.

Division of Cardiology, Department of Pediatrics, Washington University in St. Louis School of Medicine, One Children's Place, Northwest Tower, Box 8116, St. Louis, MO, 63110, USA.

For patients with single ventricle physiology, being able to initially establish systemic blood flow and control pulmonary blood flow is critical to their long-term health. Recently, there have been descriptions in achieving this by a purely transcatheter approach with stenting of the ductus arteriosus and implanting pulmonary flow restrictors, a very appealing prospect. We review a case series of 6 patients who underwent a percutaneous modified stage 1 approach using modified Microvascular plugs (MVP) at our center between September 2019 and December 2019. Read More

View Article and Full-Text PDF

Balloon Angioplasty for Pulmonary Artery Stenosis After Complete Unifocalization and Repair of Tetralogy of Fallot With Major Aortopulmonary Collaterals.

J Invasive Cardiol 2021 May 29;33(5):E378-E386. Epub 2021 Apr 29.

Pediatric Cardiology, Stanford University School of Medicine, 750 Welch Road, Suite 325, Palo Alto, CA 94304-5731 USA.

Objectives: The objective of this study was to assess procedural outcomes of balloon pulmonary artery (PA) angioplasty procedures after complete repair of tetralogy of Fallot with major aortopulmonary collateral arteries (TOF/MAPCAs).

Background: Our approach to patients with TOF/MAPCAs emphasizes early complete unifocalization and repair. Major PA reinterventions are relatively uncommon. Read More

View Article and Full-Text PDF

How to monitor cardiovascular function in critical illness in resource-limited settings.

Curr Opin Crit Care 2021 Apr 22. Epub 2021 Apr 22.

Department of Clinical Tropical Medicine Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine Mahidol University, Bangkok, Thailand Department of Intensive Care & Laboratory of Experimental Intensive Care and Anesthesiology (L.E.I.C.A.), Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, Oxford University, Oxford, UK.

Purpose Of Review: Hemodynamic monitoring is an essential component in the care for critically ill patients. A range of tools are available and new approaches have been developed. This review summarizes their availability, affordability and feasibility for hospital settings in resource-limited settings. Read More

View Article and Full-Text PDF

How to monitor cardiovascular function in critical illness in resource-limited settings.

Curr Opin Crit Care 2021 Jun;27(3):274-281

Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine Mahidol University, Bangkok, Thailand.

Purpose Of Review: Hemodynamic monitoring is an essential component in the care for critically ill patients. A range of tools are available and new approaches have been developed. This review summarizes their availability, affordability and feasibility for hospital settings in resource-limited settings. Read More

View Article and Full-Text PDF

Accuracy of echocardiographically estimated pulmonary artery pressure in dogs with myxomatous mitral valve disease.

J Vet Cardiol 2021 Mar 24;35:90-100. Epub 2021 Mar 24.

Department of Small Animal Clinical Sciences, Virginia-Maryland College of Veterinary Medicine, Blacksburg, VA, 24061, USA.

Introduction: Echocardiographically identified pulmonary hypertension is an independent predictor of poor outcome in dogs affected by myxomatous valvular degeneration (MMVD). Systolic pulmonary arterial pressure is routinely estimated based on its relationship with the Doppler-determined velocity of tricuspid regurgitation as defined by the simplified Bernoulli equation (sPAP_D). Experimental studies suggest that the method is imperfect, but its accuracy in dogs with MMVD is not known. Read More

View Article and Full-Text PDF

Does Maintenance of Pulmonary Blood Flow Pulsatility at the Time of the Fontan Operation Improve Hemodynamic Outcome in Functionally Univentricular Hearts?

Pediatr Cardiol 2021 Apr 19. Epub 2021 Apr 19.

Department of Congenital Heart Disease, University Hospitals Bristol and Weston NHS Foundation Trust, Upper Maudlin Street, Bristol, BS2 8BJ, UK.

It is unclear whether residual anterograde pulmonary blood flow (APBF) at the time of Fontan is beneficial. Pulsatile pulmonary flow may be important in maintaining a compliant and healthy vascular circuit. We, therefore, wished to ascertain whether there was hemodynamic evidence that residual pulsatile flow at time of Fontan promotes clinical benefit. Read More

View Article and Full-Text PDF

United States Chronic Thromboembolic Pulmonary Hypertension Registry: Protocol Design.

JMIR Res Protoc 2021 Apr 13. Epub 2021 Apr 13.

Temple University Hospital, Philadelphia, US.

Background: Background: Chronic thromboembolic pulmonary hypertension (CTEPH) is a rare sequela of acute pulmonary embolism that is treatable when recognized. Awareness of this disease has increased with recent advancements in therapeutic options, but delays in diagnosis remain common and diagnostic and treatment guidelines are often not followed. Data gathered from international registries has improved our understanding of CTEPH, but this data may not be applicable to the U. Read More

View Article and Full-Text PDF

Different characteristics of mitochondrial dynamics-related miRNAs on the hemodynamics of pulmonary artery hypertension and chronic thromboembolic pulmonary hypertension.

J Cardiol 2021 Apr 6. Epub 2021 Apr 6.

Department of Cardiovascular Medicine and Hypertension, Graduate School of Medical and Dental Sciences, Kagoshima University, 8-35-1 Sakuragaoka, Kagoshima 890-8520, Japan. Electronic address:

Background: Mitochondria are dynamic organelles that undergo fission or fusion. These mitochondrial dynamics are reported to be associated with pulmonary hypertension (PH). PH is divided into 5 groups, including pulmonary artery hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH), based on its pathogenesis. Read More

View Article and Full-Text PDF

Shock and Diffuse ST-elevation in a Patient with Coronavirus Disease-2019 Disease.

J Cardiovasc Echogr 2020 Oct-Dec;30(4):223-226. Epub 2021 Jan 20.

Department of Medicine, Vascular and Emergency Medicine - Stroke Unit, University of Perugia, Perugia, Italy.

The infection by the novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is associated with significant cardiovascular morbidity and mortality. Cardiac events require prompt diagnosis and management, also in the SARS-CoV-2 era. A 58-year-old male, heavy smoker and with known SARS-CoV-2 infection, abruptly developed severe hypotension and asthenia. Read More

View Article and Full-Text PDF
January 2021

Pseudo-Wellens syndrome from sepsis-induced cardiomyopathy: a case report and review of the literature.

J Med Case Rep 2021 Apr 6;15(1):151. Epub 2021 Apr 6.

Department of Cardiology, NewYork-Presbyterian Queens, Flushing, USA.

Background: Pseudo-Wellens syndrome is a rare entity characterized by the presence of electrocardiogram (ECG) changes of Wellens syndrome but without the stenosis of the left anterior descending (LAD) coronary artery. In previous reports, pseudo-Wellens syndrome most commonly resulted from recreational drug use or unidentified etiologies. We present a unique case of pseudo-Wellens syndrome due to sepsis-induced cardiomyopathy and a review of the literature. Read More

View Article and Full-Text PDF

Cine MRI characterizes HFpEF and HFrEF in post-capillary pulmonary hypertension.

Eur J Radiol 2021 Mar 26;139:109679. Epub 2021 Mar 26.

Department of Radiology, Northwestern University, 737 N Michigan Avenue, Suite 1600, Chicago, IL, 60611, United States.

Purpose: To test the hypothesis that cine MRI can be used to characterize features of left and right ventricles in post-capillary pulmonary hypertension (PH) caused by heart failure (HF) with preserved ejection fraction (HFpEF) and HF with reduced ejection fraction (HFrEF).

Methods: With the approval of institution review board (IRB), 28 consecutive post-capillary PH patients (11 males, 62.1 ± 13. Read More

View Article and Full-Text PDF

Correlation of Computed Tomography Test Bolus Dynamics and Conventional Computed Tomography Parameters With Pulmonary Vascular Resistance in Patients With Pulmonary Arterial Hypertension.

Cureus 2021 Feb 26;13(2):e13577. Epub 2021 Feb 26.

Radiology, Aurora Health Care, Milwaukee, USA.

Objective: Pulmonary vascular resistance (PVR) is a measurement obtained with invasive right heart catheterization (RHC) that is commonly used for management of patients with pulmonary arterial hypertension (PAH). Computed tomography pulmonary angiography (CTPA) is also done as part of the workup for PAH in some cases. The aim of our study was to assess the correlation of contrast dynamic changes in the main pulmonary artery (MPA) on CTPA with PVR obtained with RHC. Read More

View Article and Full-Text PDF
February 2021

Pump flow setting and assessment of unloading in clinical practice.

Eur Heart J Suppl 2021 Mar 27;23(Suppl A):A23-A26. Epub 2021 Mar 27.

Department of Anesthesia and Intensive Care, IRCCS ISMETT, UPMC Italy, Via Ernesto Tricomi, 5, 90127 Palermo, Italy.

The rationale for mechanical circulatory support (MCS) in cardiogenic shock is to restore cardiac output in selected patients when critically low or in case of refractory cardiac arrest. Furthermore, an MCS device that moves blood from either the left atrium or the left ventricle to the systemic circulation will potentially unload the ventricle. These devices are used alone or in combination with venoarterial extracorporeal membrane oxygenation (VA-ECMO). Read More

View Article and Full-Text PDF

DIAGNOSTIC AND PREDICTIVE VALUE OF RIGHT HEART CATHETERIZATION-DERIVED MEASUREMENTS IN PULMONARY HYPERTENSION.

Wiad Lek 2021 ;74(3 cz 1):546-553

SECOND DEPARTMENT OF CARDIOLOGY, SCHOOL OF MEDICINE WITH THE DIVISION OF DENTISTRY IN ZABRZE, MEDICAL UNIVERSITY OF SILESIA, KATOWICE, POLAND.

Right heart catheterization is a unique tool not only in the diagnosis but also in the management of patients with a wide range of cardiovascular diseases. The technique dates back to the 18th century, but the biggest advances were made in the 20th century. This review focuses on pulmonary hypertension for which right heart catheterization remains the diagnostic gold standard. Read More

View Article and Full-Text PDF

Late Outcomes After Pulmonary Arterial Reconstruction in Patients With Arterial Tortuosity Syndrome.

Ann Thorac Surg 2021 Mar 31. Epub 2021 Mar 31.

Department of Pediatric Cardiac Intensive care, Prince Sultan Cardiac Center, Riyadh, Saudi Arabia.

Background: Surgical pulmonary artery reconstruction in patients with Arterial Tortuosity Syndrome (ATS) has excellent outcomes. In this study, we report our late outcomes after more than a decade of experience with such complex interventions.

Methods: We conducted a retrospective review of 33 ATS patients who underwent pulmonary artery reconstruction. Read More

View Article and Full-Text PDF

Preclinical Investigation of Trifluoperazine as a Novel Therapeutic Agent for the Treatment of Pulmonary Arterial Hypertension.

Int J Mol Sci 2021 Mar 13;22(6). Epub 2021 Mar 13.

Pulmonary Hypertension Research Group, Québec Heart and Lung Institute Research Centre, Québec City, QC G1V 4G5, Canada.

Trifluoperazine (TFP), an antipsychotic drug approved by the Food and Drug Administration, has been show to exhibit anti-cancer effects. Pulmonary arterial hypertension (PAH) is a devastating disease characterized by a progressive obliteration of small pulmonary arteries (PAs) due to exaggerated proliferation and resistance to apoptosis of PA smooth muscle cells (PASMCs). However, the therapeutic potential of TFP for correcting the cancer-like phenotype of PAH-PASMCs and improving PAH in animal models remains unknown. Read More

View Article and Full-Text PDF

Pulmonary Hypertension in Pregnancy: A Review.

Medicina (Kaunas) 2021 Mar 11;57(3). Epub 2021 Mar 11.

Internal Medicine, Texas A&M University, College Station, TX 77843, USA.

Pulmonary hypertension (PH) is a disease, which targets the pulmonary vasculature affecting the heart and the lungs, and is characterized by a vast array of signs and symptoms. These manifestations of PH in pregnancy are highly variable and non-specific hence, it is prudent to have a very keen and high index of suspicion while evaluating these patients. This rare disease can be extremely debilitating and can be associated with a poor overall prognosis. Read More

View Article and Full-Text PDF

Plasma exosomal miR-596: a novel biomarker predicts survival in patients with idiopathic pulmonary artery hypertension.

J Int Med Res 2021 Mar;49(3):3000605211002379

Department of Cardio-Pulmonary Circulation, Shanghai Pulmonary Hospital, Tongji University, School of Medicine, Shanghai, China.

Objective: To determine if plasma exosomal microRNAs (miRNAs) can predict survival in patients with idiopathic pulmonary arterial hypertension (IPAH).

Methods: The study enrolled patients with IPAH that underwent right heart catheterization. Plasma was collected and exosomal miRNAs were extracted. Read More

View Article and Full-Text PDF

Anesthetic management of a patient with situs inversus totalis undergoing coronary artery bypass grafting surgery: a case report.

JA Clin Rep 2021 Mar 29;7(1):28. Epub 2021 Mar 29.

Department of Anesthesiology and Intensive Care Unit, Gunma University Graduate School of Medicine, Maebashi, Gunma, Japan.

Background: Anesthetic management of coronary artery bypass grafting surgery (CABG) in a dextrocardia patient with situs inversus totalis is rarely encountered and seldom reported in the literature.

Case Presentation: A 76-year-old Japanese female patient had been diagnosed with situs inversus totalis and coronary artery disease of 3 vessels, and she subsequently underwent elective CABG. A preoperative examination showed almost normal results. Read More

View Article and Full-Text PDF

Agreement between continuous and intermittent pulmonary artery thermodilution for cardiac output measurement in perioperative and intensive care medicine: a systematic review and meta-analysis.

Crit Care 2021 03 29;25(1):125. Epub 2021 Mar 29.

Department of Anesthesiology, Center of Anesthesiology and Intensive Care Medicine, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany.

Background: Pulmonary artery thermodilution is the clinical reference method for cardiac output monitoring. Because both continuous and intermittent pulmonary artery thermodilution are used in clinical practice it is important to know whether cardiac output measurements by the two methods are clinically interchangeable.

Methods: We performed a systematic review and meta-analysis of clinical studies comparing cardiac output measurements assessed using continuous and intermittent pulmonary artery thermodilution in adult surgical and critically ill patients. Read More

View Article and Full-Text PDF

Vascular and Parenchymal Enhancement Assessment by Dual-Phase Dual-Energy CT in the Diagnostic Investigation of Pulmonary Hypertension.

Radiol Cardiothorac Imaging 2020 Dec 17;2(6):e200009. Epub 2020 Dec 17.

Departments of Cardiothoracic Medicine (J.L.B., B.P.M.) and Thoracic Imaging (I.V.), St George's University Hospitals NHS Foundation Trust and St George's University of London, Blackshaw Road, London SW17 0QT, England; School of Sport, Health and Applied Science, St Mary's University, London, England (C.G.); and Department of Radiology, St George's University Hospitals NHS Foundation Trust, London, England (C.S., S.S.).

Purpose: To evaluate pulmonary hypertension (PH) determination by dual-phase dual-energy CT pulmonary angiography vascular enhancement and perfused blood volume (PBV) quantification.

Materials And Methods: In this prospective study, consecutive participants who underwent both right heart catheterization and dual-phase dual-energy CT pulmonary angiography were included between 2012 and 2014. CT evaluation comprised a standard pulmonary arterial phase dual-energy CT pulmonary angiography acquisition (termed series 1) followed 7 seconds after series 1 completion by a second dual-energy CT pulmonary angiography acquisition limited to the central 10 cm of the pulmonary vasculature (termed series 2). Read More

View Article and Full-Text PDF
December 2020