19,462 results match your criteria Puerto Rico Health Sciences Journal [Journal]


Environmental correlates of total and domain-specific sedentary behaviour in young people. The UP&DOWN study.

Eur J Sport Sci 2018 Dec 14:1-11. Epub 2018 Dec 14.

a Department of Physical Education, Sport and Human Movement , Autonomous University of Madrid , C/ Francisco Tomás y Valiente, 3, 28049 , Madrid , Spain.

This study investigated the associations between the characteristics of the nearby physical environment with the total and domain-specific leisure-time sedentary behaviour (SB) in young people. The study included 1578 youth (9-18 years) from the UP&DOWN study. Total leisure-time SB was objectively-assessed by accelerometers. Read More

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December 2018

Diversification of the genus Apogon (Lacepède, 1801) (Apogonidae: Perciformes) in the tropical eastern Pacific.

Mol Phylogenet Evol 2018 Dec 11. Epub 2018 Dec 11.

Laboratorio de Biología Acuática, Facultad de Biología, Universidad Michoacana de San Nicolás de Hidalgo, Edificio "R" planta baja, Ciudad Universitaria, Morelia, Michoacán, 58030, México; Laboratorio Nacional de Análisis y Síntesis Ecológica para la Conservación de Recursos Genéticos de México, Escuela Nacional de Estudios Superiores, Unidad Morelia, Universidad Nacional Autónoma de México, Apartado Postal 27-3 (Xangari), 58089, Morelia, Michoacán, México.

We examined the role of geographic barriers and historical processes on the diversification of Apogon species within the tropical eastern Pacific (TEP). Mitochondrial and nuclear DNA sequences were used in Bayesian and Maximum likelihood analyses to generate a phylogenetic hypothesis for Apogon species. Bayesian inferences were used to date the cladogenetic events. Read More

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December 2018

Empowering Physiatrists In-Training to the Peer-Review Process.

Am J Phys Med Rehabil 2018 Dec 13. Epub 2018 Dec 13.

Department of Medicine, Division of Physical Medicine and Rehabilitation, University of Toronto.

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December 2018

Rehabilitation - key for healthy ageing and longevity.

Am J Phys Med Rehabil 2018 Dec 13. Epub 2018 Dec 13.

Department of Health Sciences and Health Policy, University of Lucerne, Lucerne, Switzerland. Swiss Paraplegic Research (SPF), Nottwil, Switzerland. Department of Health Sciences and Health Policy, University of Lucerne, Lucerne, Switzerland. Swiss Paraplegic Research (SPF), Nottwil, Switzerland. University of Puerto Rico School of Medicine, San Juan, Puerto Rico, USA.

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December 2018

Direct and indirect effects of climate on richness drive the latitudinal diversity gradient in forest trees.

Ecol Lett 2018 Dec 12. Epub 2018 Dec 12.

ECNU-Alberta Joint Lab for Biodiversity Study, Tiantong National Station for Forest Ecosystem Research, East China Normal University, 200241, Shanghai.

Climate is widely recognised as an important determinant of the latitudinal diversity gradient. However, most existing studies make no distinction between direct and indirect effects of climate, which substantially hinders our understanding of how climate constrains biodiversity globally. Using data from 35 large forest plots, we test hypothesised relationships amongst climate, topography, forest structural attributes (stem abundance, tree size variation and stand basal area) and tree species richness to better understand drivers of latitudinal tree diversity patterns. Read More

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December 2018

Changes in compliance with school-based physical activity recommendations in Spanish youth: The UP&DOWN longitudinal study.

Scand J Med Sci Sports 2018 Dec 12. Epub 2018 Dec 12.

Department of Physical Education, Faculty of Education Sciences, University of Cadiz, Puerto Real, Spain.

The study aimed (i) to examine changes in physical activity (PA) during the whole day, school hours, recess, and physical education classes (PEC) during a 2-year period in primary and secondary students; (ii) to identify changes in the proportion of compliance with specific PA recommendations for these periods; and (iii) to examine whether PA levels at baseline are associated with PA levels 2 years later. Eight hundred fourteen (51.8% boys) children and 658 (50. Read More

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December 2018

Hindfoot Fusion Nail with Adjuvant Hybrid External Fixation used as Limb-Salvage Procedure after Failed Open Reduction Internal Fixation of Ankle Fracture in a Charcot Joint: A Case Report.

P R Health Sci J 2018 Dec;37(4):235-238

Department of Orthopedic Surgery, School of Medicine, University of Puerto Rico Medical Sciences Campus, San Juan, PR.

The failure of the internal fixation of an ankle fracture due to Charcot joint/ neuroarthropathy is rare; such occurred in the case of a 52-year-old woman with uncontrolled diabetes who sustained a right ankle fracture after falling from standing height. The patient was treated with the internal fixation of both malleoli, which procedure failed as the patient progressed, until she eventually was diagnosed with Charcot arthropathy. The post operative images were reviewed and showed a catastrophic fixation failure with a diagnosis of Charcot neuroarthropathy. Read More

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December 2018

Breast Asymmetry in Women Requesting Plastic Surgery of the Breast.

Authors:
Norma I Cruz

P R Health Sci J 2018 Dec;37(4):230-238

Department of Surgery, Div. of Plastic Surgery, School of Medicine, University of Puerto Rico Medical Sciences Campus, San Juan, PR.

Objective: Breast asymmetries have a high prevalence among women requesting breast augmentation. However, the prevalence of breast asymmetries in women undergoing other types of breast surgeries is not known.

Methods: The breast measurements of consecutively women evaluated for plastic surgery of the breast, but without prior breast surgery, were prospectively recorded in a plastic surgery database. Read More

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December 2018

Circumferential Stabilization of the Thoracolumbar Junction Via Posterior-Only Approach for the Management of Burst Fractures.

P R Health Sci J 2018 Dec;37(4):224-229

Department of Surgery, Neurosurgery Section, University of Puerto Rico Medical Sciences Campus, San Juan, Puerto Rico.

Objective: The management of thoracolumbar burst fractures often includes combined anterior/posterior approaches with prolonged operative time and complications. The transpedicular approach offers a posterior only approach with circumferential reconstruction and decompression. We aim to present the experience of a single center in the management of thoracolumbar burst fractures using a posterior-only approach for circumferential stabilization and report on this technique's effectiveness in restoring the alignment of the thoracolumbar junction. Read More

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December 2018

Traumatic Vascular Injury and its Management with Temporary Intravascular Shunts: A Puerto Rico Trauma Hospital's Experience.

P R Health Sci J 2018 Dec;37(4):220-223

Department of Surgery, School of Medicine, University of Puerto Rico Medical Sciences Campus, San Juan, PR; Puerto Rico Trauma Hospital, Puerto Rico Medical Center, San Juan, PR.

Objective: Temporary intravascular shunts (TIVSs) are commonly used as a damagecontrol procedure in trauma settings. Currently, there is scarce literature in the civilian field, and what there is is limited to large trauma centers with multiple resources. Therefore, we aimed to describe TIVS usage, and the outcomes of that usage, at Puerto Rico Trauma Hospital. Read More

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December 2018

A Comparative Analysis of the Injury Patterns and In-Hospital Mortality Rates of Belted and Unbelted Motor-Vehicle Occupants - Puerto Rico, January 2000 to December 2014.

P R Health Sci J 2018 Diciembre;37(4):213-219

Puerto Rico Trauma Hospital, Puerto Rico Medical Center, San Juan, PR; Department of Surgery, School of Medicine, University of Puerto Rico Medical Sciences Campus, San Juan, PR.

Objective: Motor vehicle collisions (MVCs) constitute a leading source of morbidity and mortality worldwide. Seatbelt use has been associated with reduced mortality in MVCs. In Puerto Rico, the impact of seatbelt use on MVC deaths has not been evaluated, although they represent a major public health threat. Read More

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December 2018

Experiences of Obese Adolescents trying to Reach a Healthy Weight: Considerations for the Development of a Curriculum Guide.

P R Health Sci J 2018 Dec;37(4):208-212

School of Education, Interamerican University of Puerto Rico, Metro Campus, San Juan, PR.

Objective: Obesity, almost all around the world, has been described by the medical authorities as the most common pediatric illness in children and youngsters. The purpose of this study is to explore, describe, and analyze the experiences of obese adolescents on being obese and trying to reach a healthy weight.

Design And Methods: A convenience sample of eight obese adolescents from 15 to 17 years old of both genders from three high schools of the educational region of San Juan, Puerto Rico was obtained. Read More

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December 2018

Family Environment Scale Parental Ratings of Conflict among Latino Families of Depressed Adolescents with Type 1 Diabetes.

P R Health Sci J 2018 Dec;37(4):200-207

Institute for Psychological Research, University of Puerto Rico Río Piedras Campus, San Juan, PR.

Objective: Family conflict is related to depression, difficulties with treatment adherence and glycemic control, in adolescents with type 1 diabetes (T1D). We examined the psychometric properties of a parent-rated family conflict measure and the most frequent behaviors endorsed by caregivers of these youths.

Methods: Participants were 51 caregivers (86. Read More

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December 2018

Chikungunya Virus: History, Geographic Distribution, Clinical Picture, and Treatment.

P R Health Sci J 2018 Dec;37(4):187-194

Third-year medical student, University of Puerto Rico Medical Sciences Campus, San Juan, PR.

Chikungunya fever (CHIKF) is a re-emerging mosquito-borne disease caused by a virus endemic to Africa and Asia. Due to the ease with which its vectors propagate, the virus has spread to India and Europe, and more recently it arrived to the Caribbean, eventually extending into North, Central, and South America. According to the World Health Organization (WHO), the most common clinical manifestations are abrupt fever, polyarthralgia, headache, maculopapular rash, myalgia, and nausea/vomiting. Read More

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December 2018

Evidence for the Associated Production of a Single Top Quark and a Photon in Proton-Proton Collisions at sqrt[s]=13  TeV.

Authors:
A M Sirunyan A Tumasyan W Adam F Ambrogi E Asilar T Bergauer J Brandstetter M Dragicevic J Erö A Escalante Del Valle M Flechl R Frühwirth V M Ghete J Hrubec M Jeitler N Krammer I Krätschmer D Liko T Madlener I Mikulec N Rad H Rohringer J Schieck R Schöfbeck M Spanring D Spitzbart A Taurok W Waltenberger J Wittmann C-E Wulz M Zarucki V Chekhovsky V Mossolov J Suarez Gonzalez E A De Wolf D Di Croce X Janssen J Lauwers M Pieters H Van Haevermaet P Van Mechelen N Van Remortel S Abu Zeid F Blekman J D'Hondt I De Bruyn J De Clercq K Deroover G Flouris D Lontkovskyi S Lowette I Marchesini S Moortgat L Moreels Q Python K Skovpen S Tavernier W Van Doninck P Van Mulders I Van Parijs D Beghin B Bilin H Brun B Clerbaux G De Lentdecker H Delannoy B Dorney G Fasanella L Favart R Goldouzian A Grebenyuk A K Kalsi T Lenzi J Luetic N Postiau E Starling L Thomas C Vander Velde P Vanlaer D Vannerom Q Wang T Cornelis D Dobur A Fagot M Gul I Khvastunov D Poyraz C Roskas D Trocino M Tytgat W Verbeke B Vermassen M Vit N Zaganidis H Bakhshiansohi O Bondu S Brochet G Bruno C Caputo P David C Delaere M Delcourt B Francois A Giammanco G Krintiras V Lemaitre A Magitteri A Mertens M Musich K Piotrzkowski A Saggio M Vidal Marono S Wertz J Zobec F L Alves G A Alves M Correa Martins Junior G Correia Silva C Hensel A Moraes M E Pol P Rebello Teles E Belchior Batista Das Chagas W Carvalho J Chinellato E Coelho E M Da Costa G G Da Silveira D De Jesus Damiao C De Oliveira Martins S Fonseca De Souza H Malbouisson D Matos Figueiredo M Melo De Almeida C Mora Herrera L Mundim H Nogima W L Prado Da Silva L J Sanchez Rosas A Santoro A Sznajder M Thiel E J Tonelli Manganote F Torres Da Silva De Araujo A Vilela Pereira S Ahuja C A Bernardes L Calligaris T R Fernandez Perez Tomei E M Gregores P G Mercadante S F Novaes Sandra S Padula A Aleksandrov R Hadjiiska P Iaydjiev A Marinov M Misheva M Rodozov M Shopova G Sultanov A Dimitrov L Litov B Pavlov P Petkov W Fang X Gao L Yuan M Ahmad J G Bian G M Chen H S Chen M Chen Y Chen C H Jiang D Leggat H Liao Z Liu F Romeo S M Shaheen A Spiezia J Tao Z Wang E Yazgan H Zhang S Zhang J Zhao Y Ban G Chen A Levin J Li L Li Q Li Y Mao S J Qian D Wang Z Xu Y Wang C Avila A Cabrera C A Carrillo Montoya L F Chaparro Sierra C Florez C F González Hernández M A Segura Delgado B Courbon N Godinovic D Lelas I Puljak T Sculac Z Antunovic M Kovac V Brigljevic D Ferencek K Kadija B Mesic A Starodumov T Susa M W Ather A Attikis M Kolosova G Mavromanolakis J Mousa C Nicolaou F Ptochos P A Razis H Rykaczewski M Finger M Finger E Ayala E Carrera Jarrin H Abdalla A A Abdelalim E Salama S Bhowmik A Carvalho Antunes De Oliveira R K Dewanjee K Ehataht M Kadastik M Raidal C Veelken P Eerola H Kirschenmann J Pekkanen M Voutilainen J Havukainen J K Heikkilä T Järvinen V Karimäki R Kinnunen T Lampén K Lassila-Perini S Laurila S Lehti T Lindén P Luukka T Mäenpää H Siikonen E Tuominen J Tuominiemi T Tuuva M Besancon F Couderc M Dejardin D Denegri J L Faure F Ferri S Ganjour A Givernaud P Gras G Hamel de Monchenault P Jarry C Leloup E Locci J Malcles G Negro J Rander A Rosowsky M Ö Sahin M Titov A Abdulsalam C Amendola I Antropov F Beaudette P Busson C Charlot R Granier de Cassagnac I Kucher A Lobanov J Martin Blanco C Martin Perez M Nguyen C Ochando G Ortona P Paganini P Pigard J Rembser R Salerno J B Sauvan Y Sirois A G Stahl Leiton A Zabi A Zghiche J-L Agram J Andrea D Bloch J-M Brom E C Chabert V Cherepanov C Collard E Conte J-C Fontaine D Gelé U Goerlach M Jansová A-C Le Bihan N Tonon P Van Hove S Gadrat S Beauceron C Bernet G Boudoul N Chanon R Chierici D Contardo P Depasse H El Mamouni J Fay L Finco S Gascon M Gouzevitch G Grenier B Ille F Lagarde I B Laktineh H Lattaud M Lethuillier L Mirabito S Perries A Popov V Sordini G Touquet M Vander Donckt S Viret A Khvedelidze Z Tsamalaidze C Autermann L Feld M K Kiesel K Klein M Lipinski M Preuten M P Rauch C Schomakers J Schulz M Teroerde B Wittmer V Zhukov A Albert D Duchardt M Endres M Erdmann S Erdweg T Esch R Fischer S Ghosh A Güth T Hebbeker C Heidemann K Hoepfner H Keller L Mastrolorenzo M Merschmeyer A Meyer P Millet S Mukherjee T Pook M Radziej H Reithler M Rieger A Schmidt D Teyssier S Thüer G Flügge O Hlushchenko T Kress A Künsken T Müller A Nehrkorn A Nowack C Pistone O Pooth D Roy H Sert A Stahl M Aldaya Martin T Arndt C Asawatangtrakuldee I Babounikau K Beernaert O Behnke U Behrens A Bermúdez Martínez D Bertsche A A Bin Anuar K Borras V Botta A Campbell P Connor C Contreras-Campana V Danilov A De Wit M M Defranchis C Diez Pardos D Domínguez Damiani G Eckerlin T Eichhorn A Elwood E Eren E Gallo A Geiser A Grohsjean M Guthoff M Haranko A Harb J Hauk H Jung M Kasemann J Keaveney C Kleinwort J Knolle D Krücker W Lange A Lelek T Lenz J Leonard K Lipka W Lohmann R Mankel I-A Melzer-Pellmann A B Meyer M Meyer M Missiroli G Mittag J Mnich V Myronenko S K Pflitsch D Pitzl A Raspereza M Savitskyi P Saxena P Schütze C Schwanenberger R Shevchenko A Singh H Tholen O Turkot A Vagnerini G P Van Onsem R Walsh Y Wen K Wichmann C Wissing O Zenaiev R Aggleton S Bein L Benato A Benecke V Blobel T Dreyer E Garutti D Gonzalez P Gunnellini J Haller A Hinzmann A Karavdina G Kasieczka R Klanner R Kogler N Kovalchuk S Kurz V Kutzner J Lange D Marconi J Multhaup M Niedziela C E N Niemeyer D Nowatschin A Perieanu A Reimers O Rieger C Scharf P Schleper S Schumann J Schwandt J Sonneveld H Stadie G Steinbrück F M Stober M Stöver A Vanhoefer B Vormwald I Zoi M Akbiyik C Barth M Baselga S Baur E Butz R Caspart T Chwalek F Colombo W De Boer A Dierlamm K El Morabit N Faltermann B Freund M Giffels M A Harrendorf F Hartmann S M Heindl U Husemann F Kassel I Katkov S Kudella H Mildner S Mitra M U Mozer Th Müller M Plagge G Quast K Rabbertz M Schröder I Shvetsov G Sieber H J Simonis R Ulrich S Wayand M Weber T Weiler S Williamson C Wöhrmann R Wolf G Anagnostou G Daskalakis T Geralis A Kyriakis D Loukas G Paspalaki I Topsis-Giotis G Karathanasis S Kesisoglou P Kontaxakis A Panagiotou I Papavergou N Saoulidou E Tziaferi K Vellidis K Kousouris I Papakrivopoulos G Tsipolitis I Evangelou C Foudas P Gianneios P Katsoulis P Kokkas S Mallios N Manthos I Papadopoulos E Paradas J Strologas F A Triantis D Tsitsonis M Bartók M Csanad N Filipovic P Major M I Nagy G Pasztor O Surányi G I Veres G Bencze C Hajdu D Horvath Á Hunyadi F Sikler T Á Vámi V Veszpremi G Vesztergombi N Beni S Czellar J Karancsi A Makovec J Molnar Z Szillasi P Raics Z L Trocsanyi B Ujvari S Choudhury J R Komaragiri P C Tiwari S Bahinipati C Kar P Mal K Mandal A Nayak D K Sahoo S K Swain S Bansal S B Beri V Bhatnagar S Chauhan R Chawla N Dhingra R Gupta A Kaur M Kaur S Kaur R Kumar P Kumari M Lohan A Mehta K Sandeep S Sharma J B Singh A K Virdi G Walia A Bhardwaj B C Choudhary R B Garg M Gola S Keshri Ashok Kumar S Malhotra M Naimuddin P Priyanka K Ranjan Aashaq Shah R Sharma R Bhardwaj M Bharti R Bhattacharya S Bhattacharya U Bhawandeep D Bhowmik S Dey S Dutt S Dutta S Ghosh K Mondal S Nandan A Purohit P K Rout A Roy S Roy Chowdhury G Saha S Sarkar M Sharan B Singh S Thakur P K Behera R Chudasama D Dutta V Jha V Kumar P K Netrakanti L M Pant P Shukla T Aziz M A Bhat S Dugad G B Mohanty N Sur B Sutar Ravindra Kumar Verma S Banerjee S Bhattacharya S Chatterjee P Das M Guchait Sa Jain S Karmakar S Kumar M Maity G Majumder K Mazumdar N Sahoo T Sarkar S Chauhan S Dube V Hegde A Kapoor K Kothekar S Pandey A Rane S Sharma S Chenarani E Eskandari Tadavani S M Etesami M Khakzad M Mohammadi Najafabadi M Naseri F Rezaei Hosseinabadi B Safarzadeh M Zeinali M Felcini M Grunewald M Abbrescia C Calabria A Colaleo D Creanza L Cristella N De Filippis M De Palma A Di Florio F Errico L Fiore A Gelmi G Iaselli M Ince S Lezki G Maggi M Maggi G Miniello S My S Nuzzo A Pompili G Pugliese R Radogna A Ranieri G Selvaggi A Sharma L Silvestris R Venditti P Verwilligen G Zito G Abbiendi C Battilana D Bonacorsi L Borgonovi S Braibant-Giacomelli R Campanini P Capiluppi A Castro F R Cavallo S S Chhibra C Ciocca G Codispoti M Cuffiani G M Dallavalle F Fabbri A Fanfani E Fontanesi P Giacomelli C Grandi L Guiducci F Iemmi S Lo Meo S Marcellini G Masetti A Montanari F L Navarria A Perrotta F Primavera T Rovelli G P Siroli N Tosi S Albergo A Di Mattia R Potenza A Tricomi C Tuve G Barbagli K Chatterjee V Ciulli C Civinini R D'Alessandro E Focardi G Latino P Lenzi M Meschini S Paoletti L Russo G Sguazzoni D Strom L Viliani L Benussi S Bianco F Fabbri D Piccolo F Ferro F Ravera E Robutti S Tosi A Benaglia A Beschi L Brianza F Brivio V Ciriolo S Di Guida M E Dinardo S Fiorendi S Gennai A Ghezzi P Govoni M Malberti S Malvezzi A Massironi D Menasce F Monti L Moroni M Paganoni D Pedrini S Ragazzi T Tabarelli de Fatis D Zuolo S Buontempo N Cavallo A Di Crescenzo F Fabozzi F Fienga G Galati A O M Iorio W A Khan L Lista S Meola P Paolucci C Sciacca E Voevodina P Azzi N Bacchetta D Bisello A Boletti A Bragagnolo R Carlin P Checchia M Dall'Osso P De Castro Manzano T Dorigo U Dosselli F Gasparini U Gasparini A Gozzelino S Y Hoh S Lacaprara P Lujan M Margoni A T Meneguzzo J Pazzini P Ronchese R Rossin F Simonetto A Tiko E Torassa M Zanetti P Zotto G Zumerle A Braghieri A Magnani P Montagna S P Ratti V Re M Ressegotti C Riccardi P Salvini I Vai P Vitulo M Biasini G M Bilei C Cecchi D Ciangottini L Fanò P Lariccia R Leonardi E Manoni G Mantovani V Mariani M Menichelli A Rossi A Santocchia D Spiga K Androsov P Azzurri G Bagliesi L Bianchini T Boccali L Borrello R Castaldi M A Ciocci R Dell'Orso G Fedi F Fiori L Giannini A Giassi M T Grippo F Ligabue E Manca G Mandorli A Messineo F Palla A Rizzi P Spagnolo R Tenchini G Tonelli A Venturi P G Verdini L Barone F Cavallari M Cipriani D Del Re E Di Marco M Diemoz S Gelli E Longo B Marzocchi P Meridiani G Organtini F Pandolfi R Paramatti F Preiato S Rahatlou C Rovelli F Santanastasio N Amapane R Arcidiacono S Argiro M Arneodo N Bartosik R Bellan C Biino N Cartiglia F Cenna S Cometti M Costa R Covarelli N Demaria B Kiani C Mariotti S Maselli E Migliore V Monaco E Monteil M Monteno M M Obertino L Pacher N Pastrone M Pelliccioni G L Pinna Angioni A Romero M Ruspa R Sacchi K Shchelina V Sola A Solano D Soldi A Staiano S Belforte V Candelise M Casarsa F Cossutti A Da Rold G Della Ricca F Vazzoler A Zanetti D H Kim G N Kim M S Kim J Lee S Lee S W Lee C S Moon Y D Oh S I Pak S Sekmen D C Son Y C Yang H Kim D H Moon G Oh J Goh T J Kim S Cho S Choi Y Go D Gyun S Ha B Hong Y Jo K Lee K S Lee S Lee J Lim S K Park Y Roh H S Kim J Almond J Kim J S Kim H Lee K Lee K Nam S B Oh B C Radburn-Smith S H Seo U K Yang H D Yoo G B Yu D Jeon H Kim J H Kim J S H Lee I C Park Y Choi C Hwang J Lee I Yu V Dudenas A Juodagalvis J Vaitkus I Ahmed Z A Ibrahim M A B Md Ali F Mohamad Idris W A T Wan Abdullah M N Yusli Z Zolkapli J F Benitez A Castaneda Hernandez J A Murillo Quijada H Castilla-Valdez E De La Cruz-Burelo M C Duran-Osuna I Heredia-De La Cruz R Lopez-Fernandez J Mejia Guisao R I Rabadan-Trejo M Ramirez-Garcia G Ramirez-Sanchez R Reyes-Almanza A Sanchez-Hernandez S Carrillo Moreno C Oropeza Barrera F Vazquez Valencia J Eysermans I Pedraza H A Salazar Ibarguen C Uribe Estrada A Morelos Pineda D Krofcheck S Bheesette P H Butler A Ahmad M Ahmad M I Asghar Q Hassan H R Hoorani A Saddique M A Shah M Shoaib M Waqas H Bialkowska M Bluj B Boimska T Frueboes M Górski M Kazana M Szleper P Traczyk P Zalewski K Bunkowski A Byszuk K Doroba A Kalinowski M Konecki J Krolikowski M Misiura M Olszewski A Pyskir M Walczak M Araujo P Bargassa C Beirão Da Cruz E Silva A Di Francesco P Faccioli B Galinhas M Gallinaro J Hollar N Leonardo M V Nemallapudi J Seixas G Strong O Toldaiev D Vadruccio J Varela S Afanasiev P Bunin M Gavrilenko I Golutvin I Gorbunov A Kamenev V Karjavine A Lanev A Malakhov V Matveev P Moisenz V Palichik V Perelygin S Shmatov S Shulha N Skatchkov V Smirnov N Voytishin A Zarubin V Golovtsov Y Ivanov V Kim E Kuznetsova P Levchenko V Murzin V Oreshkin I Smirnov D Sosnov V Sulimov L Uvarov S Vavilov A Vorobyev Yu Andreev A Dermenev S Gninenko N Golubev A Karneyeu M Kirsanov N Krasnikov A Pashenkov D Tlisov A Toropin V Epshteyn V Gavrilov N Lychkovskaya V Popov I Pozdnyakov G Safronov A Spiridonov A Stepennov V Stolin M Toms E Vlasov A Zhokin T Aushev R Chistov M Danilov P Parygin D Philippov S Polikarpov E Tarkovskii V Andreev M Azarkin I Dremin M Kirakosyan S V Rusakov A Terkulov A Baskakov A Belyaev E Boos V Bunichev M Dubinin L Dudko V Klyukhin O Kodolova N Korneeva I Lokhtin I Miagkov S Obraztsov M Perfilov V Savrin P Volkov A Barnyakov V Blinov T Dimova L Kardapoltsev Y Skovpen I Azhgirey I Bayshev S Bitioukov D Elumakhov A Godizov V Kachanov A Kalinin D Konstantinov P Mandrik V Petrov R Ryutin S Slabospitskii A Sobol S Troshin N Tyurin A Uzunian A Volkov A Babaev S Baidali V Okhotnikov P Adzic P Cirkovic D Devetak M Dordevic J Milosevic J Alcaraz Maestre A Álvarez Fernández I Bachiller M Barrio Luna J A Brochero Cifuentes M Cerrada N Colino B De La Cruz A Delgado Peris C Fernandez Bedoya J P Fernández Ramos J Flix M C Fouz O Gonzalez Lopez S Goy Lopez J M Hernandez M I Josa D Moran A Pérez-Calero Yzquierdo J Puerta Pelayo I Redondo L Romero M S Soares A Triossi C Albajar J F de Trocóniz J Cuevas C Erice J Fernandez Menendez S Folgueras I Gonzalez Caballero J R González Fernández E Palencia Cortezon V Rodríguez Bouza S Sanchez Cruz P Vischia J M Vizan Garcia I J Cabrillo A Calderon B Chazin Quero J Duarte Campderros M Fernandez P J Fernández Manteca A García Alonso J Garcia-Ferrero G Gomez A Lopez Virto J Marco C Martinez Rivero P Martinez Ruiz Del Arbol F Matorras J Piedra Gomez C Prieels T Rodrigo A Ruiz-Jimeno L Scodellaro N Trevisani I Vila R Vilar Cortabitarte N Wickramage D Abbaneo B Akgun E Auffray G Auzinger P Baillon A H Ball D Barney J Bendavid M Bianco A Bocci C Botta E Brondolin T Camporesi M Cepeda G Cerminara E Chapon Y Chen G Cucciati D d'Enterria A Dabrowski N Daci V Daponte A David A De Roeck N Deelen M Dobson M Dünser N Dupont A Elliott-Peisert P Everaerts F Fallavollita D Fasanella G Franzoni J Fulcher W Funk D Gigi A Gilbert K Gill F Glege M Guilbaud D Gulhan J Hegeman C Heidegger V Innocente A Jafari P Janot O Karacheban J Kieseler A Kornmayer M Krammer C Lange P Lecoq C Lourenço L Malgeri M Mannelli F Meijers J A Merlin S Mersi E Meschi P Milenovic F Moortgat M Mulders J Ngadiuba S Nourbakhsh S Orfanelli L Orsini F Pantaleo L Pape E Perez M Peruzzi A Petrilli G Petrucciani A Pfeiffer M Pierini F M Pitters D Rabady A Racz T Reis G Rolandi M Rovere H Sakulin C Schäfer C Schwick M Seidel M Selvaggi A Sharma P Silva P Sphicas A Stakia J Steggemann M Tosi D Treille A Tsirou V Veckalns M Verzetti W D Zeuner L Caminada K Deiters W Erdmann R Horisberger Q Ingram H C Kaestli D Kotlinski U Langenegger T Rohe S A Wiederkehr M Backhaus L Bäni P Berger N Chernyavskaya G Dissertori M Dittmar M Donegà C Dorfer T A Gómez Espinosa C Grab D Hits T Klijnsma W Lustermann R A Manzoni M Marionneau M T Meinhard F Micheli P Musella F Nessi-Tedaldi J Pata F Pauss G Perrin L Perrozzi S Pigazzini M Quittnat C Reissel D Ruini D A Sanz Becerra M Schönenberger L Shchutska V R Tavolaro K Theofilatos M L Vesterbacka Olsson R Wallny D H Zhu T K Aarrestad C Amsler D Brzhechko M F Canelli A De Cosa R Del Burgo S Donato C Galloni T Hreus B Kilminster S Leontsinis I Neutelings D Pinna G Rauco P Robmann D Salerno K Schweiger C Seitz Y Takahashi A Zucchetta Y H Chang K Y Cheng T H Doan R Khurana C M Kuo W Lin A Pozdnyakov S S Yu P Chang Y Chao K F Chen P H Chen W-S Hou Arun Kumar Y F Liu R-S Lu E Paganis A Psallidas A Steen B Asavapibhop N Srimanobhas N Suwonjandee A Bat F Boran S Cerci S Damarseckin Z S Demiroglu F Dolek C Dozen I Dumanoglu S Girgis G Gokbulut Y Guler E Gurpinar I Hos C Isik E E Kangal O Kara A Kayis Topaksu U Kiminsu M Oglakci G Onengut K Ozdemir S Ozturk D Sunar Cerci B Tali U G Tok S Turkcapar I S Zorbakir C Zorbilmez B Isildak G Karapinar M Yalvac M Zeyrek I O Atakisi E Gülmez M Kaya O Kaya S Ozkorucuklu S Tekten E A Yetkin M N Agaras A Cakir K Cankocak Y Komurcu S Sen B Grynyov L Levchuk F Ball L Beck J J Brooke D Burns E Clement D Cussans O Davignon H Flacher J Goldstein G P Heath H F Heath L Kreczko D M Newbold S Paramesvaran B Penning T Sakuma D Smith V J Smith J Taylor A Titterton K W Bell A Belyaev C Brew R M Brown D Cieri D J A Cockerill J A Coughlan K Harder S Harper J Linacre E Olaiya D Petyt C H Shepherd-Themistocleous A Thea I R Tomalin T Williams W J Womersley R Bainbridge P Bloch J Borg S Breeze O Buchmuller A Bundock D Colling P Dauncey G Davies M Della Negra R Di Maria Y Haddad G Hall G Iles T James M Komm C Laner L Lyons A-M Magnan S Malik A Martelli J Nash A Nikitenko V Palladino M Pesaresi D M Raymond A Richards A Rose E Scott C Seez A Shtipliyski G Singh M Stoye T Strebler S Summers A Tapper K Uchida T Virdee N Wardle D Winterbottom J Wright S C Zenz J E Cole P R Hobson A Khan P Kyberd C K Mackay A Morton I D Reid L Teodorescu S Zahid K Call J Dittmann K Hatakeyama H Liu C Madrid B Mcmaster N Pastika C Smith R Bartek A Dominguez A Buccilli S I Cooper C Henderson P Rumerio C West D Arcaro T Bose D Gastler D Rankin C Richardson J Rohlf L Sulak D Zou G Benelli X Coubez D Cutts M Hadley J Hakala U Heintz J M Hogan K H M Kwok E Laird G Landsberg J Lee Z Mao M Narain S Sagir R Syarif E Usai D Yu R Band C Brainerd R Breedon D Burns M Calderon De La Barca Sanchez M Chertok J Conway R Conway P T Cox R Erbacher C Flores G Funk W Ko O Kukral R Lander M Mulhearn D Pellett J Pilot S Shalhout M Shi D Stolp D Taylor K Tos M Tripathi Z Wang F Zhang M Bachtis C Bravo R Cousins A Dasgupta A Florent J Hauser M Ignatenko N Mccoll S Regnard D Saltzberg C Schnaible V Valuev E Bouvier K Burt R Clare J W Gary S M A Ghiasi Shirazi G Hanson G Karapostoli E Kennedy F Lacroix O R Long M Olmedo Negrete M I Paneva W Si L Wang H Wei S Wimpenny B R Yates J G Branson P Chang S Cittolin M Derdzinski R Gerosa D Gilbert B Hashemi A Holzner D Klein G Kole V Krutelyov J Letts M Masciovecchio D Olivito S Padhi M Pieri M Sani V Sharma S Simon M Tadel A Vartak S Wasserbaech J Wood F Würthwein A Yagil G Zevi Della Porta N Amin R Bhandari J Bradmiller-Feld C Campagnari M Citron A Dishaw V Dutta M Franco Sevilla L Gouskos R Heller J Incandela A Ovcharova H Qu J Richman D Stuart I Suarez S Wang J Yoo D Anderson A Bornheim J M Lawhorn H B Newman T Q Nguyen M Spiropulu J R Vlimant R Wilkinson S Xie Z Zhang R Y Zhu M B Andrews T Ferguson T Mudholkar M Paulini M Sun I Vorobiev M Weinberg J P Cumalat W T Ford F Jensen A Johnson M Krohn E MacDonald T Mulholland R Patel K Stenson K A Ulmer S R Wagner J Alexander J Chaves Y Cheng J Chu A Datta K Mcdermott N Mirman J R Patterson D Quach A Rinkevicius A Ryd L Skinnari L Soffi S M Tan Z Tao J Thom J Tucker P Wittich M Zientek S Abdullin M Albrow M Alyari G Apollinari A Apresyan A Apyan S Banerjee L A T Bauerdick A Beretvas J Berryhill P C Bhat G Bolla K Burkett J N Butler A Canepa G B Cerati H W K Cheung F Chlebana M Cremonesi J Duarte V D Elvira J Freeman Z Gecse E Gottschalk L Gray D Green S Grünendahl O Gutsche J Hanlon R M Harris S Hasegawa J Hirschauer Z Hu B Jayatilaka S Jindariani M Johnson U Joshi B Klima M J Kortelainen B Kreis S Lammel D Lincoln R Lipton M Liu T Liu J Lykken K Maeshima J M Marraffino D Mason P McBride P Merkel S Mrenna S Nahn V O'Dell K Pedro C Pena O Prokofyev G Rakness L Ristori A Savoy-Navarro B Schneider E Sexton-Kennedy A Soha W J Spalding L Spiegel S Stoynev J Strait N Strobbe L Taylor S Tkaczyk N V Tran L Uplegger E W Vaandering C Vernieri M Verzocchi R Vidal M Wang H A Weber A Whitbeck D Acosta P Avery P Bortignon D Bourilkov A Brinkerhoff L Cadamuro A Carnes M Carver D Curry R D Field S V Gleyzer B M Joshi J Konigsberg A Korytov K H Lo P Ma K Matchev H Mei G Mitselmakher D Rosenzweig K Shi D Sperka J Wang S Wang X Zuo Y R Joshi S Linn A Ackert T Adams A Askew S Hagopian V Hagopian K F Johnson T Kolberg G Martinez T Perry H Prosper A Saha C Schiber R Yohay M M Baarmand V Bhopatkar S Colafranceschi M Hohlmann D Noonan M Rahmani T Roy F Yumiceva M R Adams L Apanasevich D Berry R R Betts R Cavanaugh X Chen S Dittmer O Evdokimov C E Gerber D A Hangal D J Hofman K Jung J Kamin C Mills I D Sandoval Gonzalez M B Tonjes H Trauger N Varelas H Wang X Wang Z Wu J Zhang M Alhusseini B Bilki W Clarida K Dilsiz S Durgut R P Gandrajula M Haytmyradov V Khristenko J-P Merlo A Mestvirishvili A Moeller J Nachtman H Ogul Y Onel F Ozok A Penzo C Snyder E Tiras J Wetzel B Blumenfeld A Cocoros N Eminizer D Fehling L Feng A V Gritsan W T Hung P Maksimovic J Roskes U Sarica M Swartz M Xiao C You A Al-Bataineh P Baringer A Bean S Boren J Bowen A Bylinkin J Castle S Khalil A Kropivnitskaya D Majumder W Mcbrayer M Murray C Rogan S Sanders E Schmitz J D Tapia Takaki Q Wang S Duric A Ivanov K Kaadze D Kim Y Maravin D R Mendis T Mitchell A Modak A Mohammadi L K Saini N Skhirtladze F Rebassoo D Wright A Baden O Baron A Belloni S C Eno Y Feng C Ferraioli N J Hadley S Jabeen G Y Jeng R G Kellogg J Kunkle A C Mignerey S Nabili F Ricci-Tam Y H Shin A Skuja S C Tonwar K Wong D Abercrombie B Allen V Azzolini A Baty G Bauer R Bi S Brandt W Busza I A Cali M D'Alfonso Z Demiragli G Gomez Ceballos M Goncharov P Harris D Hsu M Hu Y Iiyama G M Innocenti M Klute D Kovalskyi Y-J Lee P D Luckey B Maier A C Marini C Mcginn C Mironov S Narayanan X Niu C Paus C Roland G Roland G S F Stephans K Sumorok K Tatar D Velicanu J Wang T W Wang B Wyslouch S Zhaozhong A C Benvenuti R M Chatterjee A Evans P Hansen Sh Jain S Kalafut Y Kubota Z Lesko J Mans N Ruckstuhl R Rusack J Turkewitz M A Wadud J G Acosta S Oliveros E Avdeeva K Bloom D R Claes C Fangmeier F Golf R Gonzalez Suarez R Kamalieddin I Kravchenko J Monroy J E Siado G R Snow B Stieger A Godshalk C Harrington I Iashvili A Kharchilava C Mclean D Nguyen A Parker S Rappoccio B Roozbahani G Alverson E Barberis C Freer A Hortiangtham D M Morse T Orimoto R Teixeira De Lima T Wamorkar B Wang A Wisecarver D Wood S Bhattacharya O Charaf K A Hahn N Mucia N Odell M H Schmitt K Sung M Trovato M Velasco R Bucci N Dev M Hildreth K Hurtado Anampa C Jessop D J Karmgard N Kellams K Lannon W Li N Loukas N Marinelli F Meng C Mueller Y Musienko M Planer A Reinsvold R Ruchti P Siddireddy G Smith S Taroni M Wayne A Wightman M Wolf A Woodard J Alimena L Antonelli B Bylsma L S Durkin S Flowers B Francis A Hart C Hill W Ji T Y Ling W Luo B L Winer S Cooperstein P Elmer J Hardenbrook S Higginbotham A Kalogeropoulos D Lange M T Lucchini J Luo D Marlow K Mei I Ojalvo J Olsen C Palmer P Piroué J Salfeld-Nebgen D Stickland C Tully S Malik S Norberg A Barker V E Barnes S Das L Gutay M Jones A W Jung A Khatiwada B Mahakud D H Miller N Neumeister C C Peng S Piperov H Qiu J F Schulte J Sun F Wang R Xiao W Xie T Cheng J Dolen N Parashar Z Chen K M Ecklund S Freed F J M Geurts M Kilpatrick W Li B P Padley R Redjimi J Roberts J Rorie W Shi Z Tu J Zabel A Zhang A Bodek P de Barbaro R Demina Y T Duh J L Dulemba C Fallon T Ferbel M Galanti A Garcia-Bellido J Han O Hindrichs A Khukhunaishvili P Tan R Taus A Agapitos J P Chou Y Gershtein E Halkiadakis M Heindl E Hughes S Kaplan R Kunnawalkam Elayavalli S Kyriacou A Lath R Montalvo K Nash M Osherson H Saka S Salur S Schnetzer D Sheffield S Somalwar R Stone S Thomas P Thomassen M Walker A G Delannoy J Heideman G Riley S Spanier O Bouhali A Celik M Dalchenko M De Mattia A Delgado S Dildick R Eusebi J Gilmore T Huang T Kamon S Luo R Mueller A Perloff L Perniè D Rathjens A Safonov N Akchurin J Damgov F De Guio P R Dudero S Kunori K Lamichhane S W Lee T Mengke S Muthumuni T Peltola S Undleeb I Volobouev Z Wang S Greene A Gurrola R Janjam W Johns C Maguire A Melo H Ni K Padeken J D Ruiz Alvarez P Sheldon S Tuo J Velkovska M Verweij Q Xu M W Arenton P Barria B Cox R Hirosky M Joyce A Ledovskoy H Li C Neu T Sinthuprasith Y Wang E Wolfe F Xia R Harr P E Karchin N Poudyal J Sturdy P Thapa S Zaleski M Brodski J Buchanan C Caillol D Carlsmith S Dasu L Dodd B Gomber M Grothe M Herndon A Hervé U Hussain P Klabbers A Lanaro K Long R Loveless T Ruggles A Savin V Sharma N Smith W H Smith N Woods

Phys Rev Lett 2018 Nov;121(22):221802

University of Wisconsin, Madison, Wisconsin, USA.

The first evidence of events consistent with the production of a single top quark in association with a photon is reported. The analysis is based on proton-proton collisions at sqrt[s]=13  TeV and recorded by the CMS experiment in 2016, corresponding to an integrated luminosity of 35.9  fb^{-1}. Read More

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November 2018
7.512 Impact Factor

Pulmonary hypertension in chronic lung disease and hypoxia.

Eur Respir J 2018 Dec 13. Epub 2018 Dec 13.

University of Giessen and Marburg Lung Center (UGMLC), Justus-Liebig University Giessen and Member of the German Center for Lung Research (DZL), Giessen, Germany.

Pulmonary hypertension (PH) frequently complicates the course of patients with various forms of chronic lung disease (CLD). CLD-associated PH (CLD-PH) is invariably associated with reduced functional ability, impaired quality of life, greater oxygen requirements and an increased risk of mortality. The aetiology of CLD-PH is complex and multifactorial, with differences in the pathogenic sequelae between the diverse forms of CLD. Read More

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December 2018

Downregulation of TREM-like transcript (TLT)-1 and collagen receptor α2 subunit, two novel RUNX1-targets, contributes to platelet dysfunction in familial platelet disorder with predisposition to acute myelogenous leukemia.

Haematologica 2018 Dec 13. Epub 2018 Dec 13.

Institute of Medical Research Alfredo Lanari. CONICET. University of Buenos Aires;

Germline RUNX1 mutations lead to thrombocytopenia and platelet dysfunction in familial platelet disorder with predisposition to acute myelogenous leukemia. Multiple aspects of platelet function are impaired in these patients, associated with altered expression of genes regulated by RUNX1. We aimed to identify RUNX1-targets involved in platelet function by combining transcriptome analysis of patient and shRUNX1-transduced megakaryocytes. Read More

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December 2018

Possible role of phytoestrogens in breast cancer via GPER-1/GPR30 signaling.

Clin Sci (Lond) 2018 Dec 13;132(24):2583-2598. Epub 2018 Dec 13.

Laboratory of Cellular Pathology, Institute of Anatomy, Histology and Pathology, Universidad Austral de Chile, Valdivia, Chile

Estrogens generated within endocrine organs and the reproductive system act as ligands for at least three types of estrogen receptors. Estrogen receptors α (ERα) and β (ERβ) belong to the so-called classical family of estrogen receptors, whereas the G protein-coupled receptor GPR30, also known as GPER-1, has been described as a novel estrogen receptor sited in the cell membrane of target cells. Furthermore, these receptors are under stimulation of a family of exogenous estrogens, known as phytoestrogens, which are a diverse group of non-steroidal plant compounds derived from plant food consumed by humans and animals. Read More

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December 2018
1 Read

Effectiveness of the Nutritional App "MyNutriCart" on Food Choices Related to Purchase and Dietary Behavior: A Pilot Randomized Controlled Trial.

Nutrients 2018 Dec 12;10(12). Epub 2018 Dec 12.

Department of Biostatistics and Epidemiology, Graduate School of Public Health, Medical Sciences Campus, University of Puerto Rico, San Juan 00935, Puerto Rico.

Objective: To pilot test the effectiveness of "MyNutriCart", a smartphone application (app) that generates healthy grocery lists, on diet and weight.

Methods: A pilot randomized trial was conducted to test the efficacy of using the "MyNutriCart" app compared to one face-to-face counseling session (Traditional group) in Hispanic overweight and obese adults. Household food purchasing behavior, three 24-h food recalls, Tucker's semi-quantitative food frequency questionnaire (FFQ), and weight were assessed at baseline and after 8 weeks. Read More

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December 2018

A Strategy to Replace the Mouse Bioassay for Detecting and Identifying Lipophilic Marine Biotoxins by Combining the Neuro-2a Bioassay and LC-MS/MS Analysis.

Mar Drugs 2018 Dec 12;16(12). Epub 2018 Dec 12.

Rikilt Wageningen and Research, 6708WB Wageningen, The Netherlands.

Marine biotoxins in fish and shellfish can cause several symptoms in consumers, such as diarrhea, amnesia, or even death by paralysis. Monitoring programs are in place for testing shellfish on a regular basis. In some countries testing is performed using the so-called mouse bioassay, an assay that faces ethical concerns not only because of animal distress, but also because it lacks specificity and results in high amounts of false positives. Read More

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December 2018

Spatial-Temporal Analysis of PM and NO₂ Concentrations Collected Using Low-Cost Sensors in Peñuelas, Puerto Rico.

Sensors (Basel) 2018 Dec 7;18(12). Epub 2018 Dec 7.

Region 2, U.S. Environmental Protection Agency, Edison, NJ 08837-3679, USA.

The U.S. Environmental Protection Agency (EPA) is involved in the discovery, evaluation, and application of low-cost air quality (AQ) sensors to support citizen scientists by directly engaging with them in the pursuit of community-based interests. Read More

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December 2018

Prevalence and incidence of Zika virus infection among household contacts of patients with Zika virus disease, Puerto Rico, 2016-2017.

J Infect Dis 2018 Dec 13. Epub 2018 Dec 13.

National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Centers for Disease Control and Prevention, San Juan, PR.

Background: Little is known about the prevalence or incidence of Zika virus (ZIKV) infection in settings affected by the 2015-16 Zika pandemic, and associated risk-factors. We assessed these factors among household contacts of patients with ZIKV disease enrolled in a cohort study in Puerto Rico during 2016-2017.

Methods: Household contacts of index case-patients completed a questionnaire and gave specimens for RT-PCR and IgM ELISA testing to detect ZIKV infection. Read More

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December 2018

What is the Value of Different Zika Vaccination Strategies to Prevent and Mitigate Zika Outbreaks.

J Infect Dis 2018 Dec 13. Epub 2018 Dec 13.

Johns Hopkins University, Baltimore, Maryland, USA.

Background: While the 2015-2016 Zika epidemics prompted accelerated vaccine development, decision makers need to know the potential economic value of vaccination strategies.

Methods: We developed models of Honduras, Brazil, and Puerto Rico, simulated targeting different populations for Zika vaccination (women of childbearing age, school-aged children, young adults, and everyone) and then introduced various Zika outbreaks. Sensitivity analyses varied vaccine characteristics. Read More

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December 2018

Influenza Activity - United States, September 30-December 1, 2018.

MMWR Morb Mortal Wkly Rep 2018 Dec 14;67(49):1369-1371. Epub 2018 Dec 14.

Influenza Division, National Center for Immunization and Respiratory Diseases, CDC.

Influenza activity in the United States was low during October 2018, and, although it increased slowly during November, activity remains low across most of the country.* During the week ending December 1, 2018, the percentage of outpatient visits for influenza-like illness (ILI) was equal to the national baseline (Figure) and was at or slightly above the region-specific baseline in four of the 10 U.S. Read More

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December 2018

extract (GLE) impairs breast cancer stem cells by targeting the STAT3 pathway.

Oncotarget 2018 Nov 13;9(89):35907-35921. Epub 2018 Nov 13.

Universidad Central del Caribe-School of Medicine, Bayamon, Puerto Rico, United States of America.

The aggressive nature of triple negative breast cancer (TNBC) may be explained in part by the presence of breast cancer stem cells (BCSCs), a subpopulation of cells, which are involved in tumor initiation, progression, metastasis, recurrence, and therapy resistance. The signal transducer and activator of transcription 3 (STAT3) pathway participates in the development and progression of BCSCs, but its role in TNBC remains unclear. Here, we report that extract (GLE), a medicinal mushroom with anticancer activity, acts on BCSCs and in TNBC pre-clinical animal tumor models by downregulating the STAT3 pathway. Read More

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November 2018

Comprehensive evaluation of differential serodiagnosis between Zika and dengue viral infection.

J Clin Microbiol 2018 Dec 12. Epub 2018 Dec 12.

US Department of Health and Human Services, Public Health Services, Division of Vector-Borne Diseases, Centers for Disease Control and Prevention, Fort Collins, Colorado 80521

Diagnostic testing for Zika virus (ZIKV) or dengue virus (DENV) infection can be accomplished by a nucleic acid detection method; however, a negative result does not exclude infection due to the low virus titer during infection depending on the timing of sample collection. Therefore, a ZIKV- or DENV-specific serological assay is essential for the accurate diagnosis of patients and to mitigate potential severe health outcomes. A retrospective study design with dual approaches of collecting human serum samples for testing was developed. Read More

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December 2018

[Clinical and socio-sanitary characteristics in adults older than 65 years attended in the Primary Care setting. The PYCAF study].

Semergen 2018 Dec 9. Epub 2018 Dec 9.

Centro de Salud La Laguna, Cádiz, España.

Objective: To describe the clinical and socio-sanitary characteristics of adults older than 65 years attended in a Primary Care setting.

Material And Methods: The PYCAF study (Prevalence and Characteristics of the Fragile Elderly) is a descriptive, cross-sectional and multicentre study, in which patients older than 65 years attended in clinical practice in Primary Care in Spain were consecutively included.

Results: A total of 2,461 patients (mean age 76. Read More

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December 2018

Associations between gestational weight gain and rate of infancy weight gain in Hawai'i and Puerto Rico WIC participants.

BMC Obes 2018 3;5:41. Epub 2018 Dec 3.

1Department of Human Nutrition, Food and Animal Sciences, College of Tropical Agriculture and Human Resources, University of Hawai'i at Mānoa. Agricultural Sciences 216, 1955 East-West Rd, Honolulu, HI 96822 USA.

Background: Excessive gestational weight gain and rapid infancy weight gain (RIWG) are associated with increased susceptibility to childhood obesity. Since low-income and minority children are particularly at risk, investigation of the associations between gestational weight gain and rate of infancy weight gain may inform childhood obesity prevention. This study investigated the associations between gestational weight gain and rate of infancy weight gain during the first four to six months postpartum in participants from the Special Supplemental Nutrition Program for Women, Infants, and Children (WIC) in Hawai'i and Puerto Rico. Read More

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December 2018

Influence of size and surface capping on photoluminescence and cytotoxicity of gold nanoparticles.

J Nanopart Res 2018 15;20(11):305. Epub 2018 Nov 15.

Institute of Biomedical Research Cádiz (INIBICA), Cádiz, Spain.

Hydrophilic and homogeneous sub-10 nm blue light-emitting gold nanoparticles (NPs) functionalized with different capping agents have been prepared by simple chemical routes. Structure, average, size, and surface characteristics of these NPs have been widely studied, and the stability of colloidal NP solutions at different pH values has been evaluated. Au NPs show blue PL emission, particularly in the GSH capped NPs, in which the thiol-metal core transference transitions considerably enhance the fluorescent emission. Read More

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November 2018

Vibrational properties of germanane and fluorinated germanene in the chair, boat, and zigzag-line configurations.

J Phys Condens Matter 2018 Nov 27. Epub 2018 Nov 27.

Grupo Teoría de Sólidos, Comision Nacional de Energia Atomica - Centro Atomico Bariloche, Bariloche, ARGENTINA.

The electronic and vibrational properties of germanane and fluorinated germanene are studied within Density Functional Theory (DFT) and Density Functional Perturbation Theory (DFPT) frameworks. Different structural configurations of germanane and fluorinated germanene are investigated. The energy difference between the different configurations are consistently smaller than the energy of thermal fluctuations for all the analyzed DFT functionals LDA, GGA, and hybrid functionals, which implies that, in principle, it is possible to find these different configurations in different regions of the sample as minority phases or local defects. Read More

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November 2018

Physicochemical and microbiological characterization of the sensory deviation responsible for the origin of the special sherry wines "palo cortado" type.

PLoS One 2018 12;13(12):e0208330. Epub 2018 Dec 12.

Department of Chemical Engineering and Food Technology, Faculty of Sciences, University of Cadiz, Cadiz, Spain.

The aim of this study was to characterize the biochemical changes and microbiological processes involved in the sensory deviation of "sobretablas" wines during biological aging, which leads to the origin of special or rare "palo cortado" wines. Industrial trials of biological aging of "sobretablas" wines with the potential for the development of lactic acid bacteria (LAB) were performed to study this phenomenon. The results showed that sensory deviation was due to the development of malolactic fermentation (MLF) together with an attenuated aerobic metabolism of "flor" yeast. Read More

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December 2018
2 Reads

PR8 virus harbouring H5N1 gene contributed for THP-1 cell tropism.

Virusdisease 2018 Dec 20;29(4):548-552. Epub 2018 Oct 20.

1Department of Microbiology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok Noi, Bangkok, Thailand.

Innate immune cells are key player in immune response to influenza virus infection. Influenza infected monocytes exacerbate the disease pathology. However, monocytes differ in susceptibilities to influenza virus infection. Read More

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December 2018
1 Read

Genetic ancestry, admixture and health determinants in Latin America.

BMC Genomics 2018 Dec 11;19(Suppl 8):861. Epub 2018 Dec 11.

School of Biological Sciences, Georgia Institute of Technology, Atlanta, GA, 30332, USA.

Background: Modern Latin American populations were formed via genetic admixture among ancestral source populations from Africa, the Americas and Europe. We are interested in studying how combinations of genetic ancestry in admixed Latin American populations may impact genomic determinants of health and disease. For this study, we characterized the impact of ancestry and admixture on genetic variants that underlie health- and disease-related phenotypes in population genomic samples from Colombia, Mexico, Peru, and Puerto Rico. Read More

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December 2018
1 Read

Social network analysis of the biblical Moses.

Authors:
Steven E Massey

Appl Netw Sci 2016 14;1(1):13. Epub 2016 Nov 14.

Department of Biology, University of Puerto Rico - Rio Piedras, San Juan, PR 00931 USA.

Here, social network analysis approaches are used to characterize the figure of the biblical Moses, and his relationship with characters from the books of the Pentateuch; Genesis, Exodus, Leviticus, Numbers and Deuteronomy. The potential value of using such quantitative approaches is explored in relation to other forms of textual exegesis. Using a maximum likelihood approach, the degree distributions of the social networks are shown to approximate to a power law with exponential cutoff. Read More

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November 2016

Effectiveness assessment of risk reduction measures at coastal areas using a decision support system: Findings from Emma storm.

Sci Total Environ 2018 Dec 1;657:124-135. Epub 2018 Dec 1.

CIMA/FCT, University of Algarve, Campus de Gambelas, 8005-139 Faro, Portugal. Electronic address:

Storms impact coastal areas often causing damages and losses at occupied areas. On a scenario of increasing human occupation at coastal zones and under climate change conditions (including sea level rise and increasing frequency of extreme sea levels), the consequences of storms are expected to be amplified if no adaptation or further management actions are implemented. The selection of the best possible coastal management measures, considering both costs and effectiveness, will be mandatory in the future, in order to optimise resources. Read More

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December 2018

Field-Evolved Resistance of the Fall Armyworm (Lepidoptera: Noctuidae) to Synthetic Insecticides in Puerto Rico and Mexico.

J Econ Entomol 2018 Dec 10. Epub 2018 Dec 10.

Department of Entomology, Michigan State University, Food Safety and Toxicology Building, East Lansing, MI.

The fall armyworm, Spodoptera frugiperda (J. E. Smith), is one of the main pests of corn in many areas of the American continent. Read More

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December 2018
1 Read

Antimicrobial resistance in Chile and The One Health paradigm: Dealing with threats to human and veterinary health resulting from antimicrobial use in salmon aquaculture and the clinic.

Rev Chilena Infectol 2018 ;35(3):299-308

Department of Microbiology and Immunology, New York Medical College, Valhalla, New York, USA.

The emergence and dissemination of antimicrobial-resistant bacteria (ARB) is currently seen as one of the major threats to human and animal public health. Veterinary use of antimicrobials in both developing and developed countries is many-fold greater than their use in human medicine and is an important determinant in selection of ARB. In light of the recently outlined National Plan Against Antimicrobial Resistance in Chile, our findings on antimicrobial use in salmon aquaculture and their impact on the environment and human health are highly relevant. Read More

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January 2018

[Experience in visceral cutaneous and cutaneous loxoscelism of hospital management: clinical, evolution and therapeutic proposal].

Rev Chilena Infectol 2018 ;35(3):266-275

Departamento de Dermatología, Pontificia Universidad Católica de Chile, Santiago, Chile.

Background: Loxoscelism is a common pathology in our environment with a broad spectrum of differential diagnoses and presentations, with potentially serious complications, even to the point of death. To date, there is no standard treatment for these patients.

Aim: To describe the clinical manifestations, main complications, therapeutic management, and evolution of loxoscelism in an inpatient setting from a tertiary hospital in Chile. Read More

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January 2018
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[Survival of 1,103 Chilean patients with multiple myeloma receiving different therapeutic protocols from 2000 to 2016].

Rev Med Chil 2018 Jul;146(7):869-875

Hospital Barros Luco Trudeau, Santiago, Chile.

Background: Multiple myeloma (MM) is one of the most common malignancies found in hematology.

Aim: To describe the features of patients with MM and perform a survival analysis according to the different treatment protocols used between 2000 and 2016.

Material And Methods: Analysis of the database of the Chilean national anti-neoplastic drug program. Read More

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[Porphyria cutanea tarda. Case report].

Rev Med Chil 2018 Aug;146(8):943-946

Escuela de Medicina, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.

Porphyria cutanea tarda (PCT) is the most common type of porphyria: it is characterized by blistering lesions, erosions and crusts on the back of the hands, associated with photosensitivity and facial hypertrichosis. It is produced by acquired or hereditary deficiency of the enzyme UROD, fifth enzyme in the chain of production of the Heme group. This causes accumulation of porphyrins in the liver, which are subsequently mobilized to the skin, where lesions are generated by photosensitivity. Read More

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The Practice of Overlapping Surgery Is Safe in Total Knee and Hip Arthroplasty.

JB JS Open Access 2018 Sep 24;3(3):e0004. Epub 2018 Jul 24.

Cleveland Clinic Florida, Weston, Florida.

Background: Overlapping surgery occurs when a surgeon performs 2 procedures in an overlapping time frame. This practice is commonplace in the setting of total joint arthroplasty and is intended to increase patient access to experienced surgeons, improve efficiency, and advance the surgical competence of surgeons and trainees. The practice of overlapping surgery has been questioned because of safety and ethical concerns. Read More

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September 2018

Coral disease prevalence estimation and sampling design.

PeerJ 2018 3;6:e6006. Epub 2018 Dec 3.

Instituto de Ciencias del Mar y Limnología, Universidad Nacional Autónoma de México, Puerto Morelos, Quintana Roo, México.

In the last decades diseases have changed coral communities' structure and function in reefs worldwide. Studies conducted to evaluate the effect of diseases on corals frequently use modified adaptations of sampling designs that were developed to study ecological aspects of coral reefs. Here we evaluate how efficient these sampling protocols are by generating virtual data for a coral population parameterized with mean coral density and disease prevalence estimates from the Caribbean scleractinian at the Mexican Caribbean. Read More

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December 2018

Elucidating the contribution of ETC complexes I and II to the respirasome formation in cardiac mitochondria.

Sci Rep 2018 Dec 7;8(1):17732. Epub 2018 Dec 7.

Department of Physiology, University of Puerto Rico School of Medicine, San Juan, PR, 00936-5067, USA.

Mitochondrial electron transport chain (ETC) plays a central role in ATP synthesis, and its dysfunction is associated with human diseases. Recent studies revealed that individual ETC complexes are assembled into supercomplexes. The main supercomplex, respirasome composed of complexes I, III, and IV has been suggested to improve electron channeling and control ROS production, maintain the structural integrity of ETC complexes and prevent protein aggregation in the inner mitochondrial membrane. Read More

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December 2018

Muscle MRI in a large cohort of patients with oculopharyngeal muscular dystrophy.

J Neurol Neurosurg Psychiatry 2018 Dec 8. Epub 2018 Dec 8.

Neuromuscular Disorders Unit, Neurology Department, Hospital de la Santa Creu I Sant Pau, Universidad Autónoma de Barcelona, Barcelona, Spain

Background And Objective: Oculopharyngeal muscular dystrophy (OPMD) is a genetic disorder caused by an abnormal expansion of GCN triplets within the gene. Previous descriptions have focused on lower limb muscles in small cohorts of patients with OPMD, but larger imaging studies have not been performed. Previous imaging studies have been too small to be able to correlate imaging findings to genetic and clinical data. Read More

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December 2018
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Inhibition of dengue virus by curcuminoids.

Antiviral Res 2018 Dec 6. Epub 2018 Dec 6.

Department of Microbiology and Immunology, Georgetown University, Washington, D.C, USA. Electronic address:

The dengue virus is considered to be a globally important human pathogen prevalent in tropical and subtropical regions of the world. According to a recent estimate, the disease burden due to DENV infections is ∼390 million infections per year globally in ∼100 countries including the southern US, Puerto Rico and Hawaii, resulting in nearly ∼25,000 deaths mostly among children. Despite the significant morbidity and mortality that results from DENV infections, there is currently no effective chemotherapeutic treatment for DENV infections. Read More

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December 2018
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Effect of bio-chemical chitosan and gallic acid into rheology and physicochemical properties of ternary edible films.

Int J Biol Macromol 2018 Dec 5. Epub 2018 Dec 5.

Centro de Investigación y Asistencia en Tecnología y Diseño del Estado de Jalisco, Sede Sureste, Parque Científico Tecnológico de Yucatán, Km 5.5. Carretera Sierra Papacal - Chuburná Puerto, Mérida, Yucatán 97302, Mexico; Cátedra-CONACyT, Dirección Adjunta de Desarrollo Científico, Consejo Nacional de Ciencia y Tecnología, Av. Insurgentes Sur 1582, Ciudad de México 03940, Mexico. Electronic address:

The ternary edible films based on commercial or bio-chemical chitosan (CCh or BCh) and starch (S) with different concentration of gallic acid (GA) were produced by casting. This work analyzed the effect of different type of Ch and GA concentrations (1.25 mg/g and 2. Read More

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December 2018

Magnetic resonance imaging quantification of dehydration and rehydration in vocal fold tissue layers.

PLoS One 2018 6;13(12):e0208763. Epub 2018 Dec 6.

Division of Otolaryngology, Department of Surgery, University of Wisconsin-Madison, Madison, Wisconsin, United States of America.

Clinicians commonly recommend increased hydration to patients with voice disorders. However, effects on clinical voice outcome measures have been inconsistent. Hydration-induced change within different layers of vocal fold tissue is currently unknown. Read More

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December 2018
3 Reads

Synthesis of novel derivatives of 7,8-dihydro-6H-imidazo[2,1-b][1,3]benzothiazol-5-one and their virus-inhibiting activity against influenza A virus.

Arch Pharm (Weinheim) 2018 Dec 6. Epub 2018 Dec 6.

Fluoro and Agrochemicals Division (Organic Chemistry Division-II), CSIR - Indian Institute of Chemical Technology, Hyderabad, India.

Influenza remains a highly pathogenic and hardly controlled human infection. The ability of selecting drug-resistant variants necessitates the search and development of novel anti-influenza drugs. Herein, we describe the synthesis and evaluation of a series of novel 2-substituted 7,8-dihydro-6H-imidazo[2,1-b][1,3]benzothiazol-5-ones 3a-k for their virus-inhibiting activity against influenza A virus. Read More

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December 2018
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Prevalence of pharmacogenomic variants affecting the efficacy of clopidogrel therapy in the Hispanic Community Health Study/Study of Latinos cohort.

Pharmacogenomics 2018 Dec 6. Epub 2018 Dec 6.

Department of Epidemiology & Population Health, Albert Einstein College of Medicine, Bronx, NY 10461, USA.

Purpose: Although clopidogrel is the most widely used oral P2Y12 receptor antagonist, up to 10% of acute coronary syndrome patients treated with clopidogrel will experience a recurrent myocardial infarction and 2-3% will experience stent thrombosis within 1 year. The purpose of this research is to describe the prevalence of pharmacogene variants associated with clopidogrel responsiveness (CYP2C19, B4GALT2, ABCB1, PON1, CES1 and P2RY12) in Hispanic/Latino patients of diverse backgrounds.

Methods: Minor allele frequencies of nine variants from participants of Hispanic Community Health Study/Study of Latinos were compared between subpopulations as well as to continental ancestry references using z-test for independent proportions. Read More

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December 2018
4 Reads