40,090 results match your criteria Ptosis Congenital


Expressions of homeobox, collagen and estrogen genes in women with uterine prolapse.

Eur J Obstet Gynecol Reprod Biol 2018 Nov 29;233:26-29. Epub 2018 Nov 29.

Ankara University, School of Medicine, Department of Biostatistics, Ankara, Turkey.

Objective: Genetic contribution is thought to be involved in the pathophysiology of pelvic organ prolapse (POP). We aimed to study the gene expression profiles of the genes HomeoboxA11 (HOXA11), HomeoboxA13 (HOXA13), Collagen Type I (COL1A), Collagen Type III (COL3A), estrogen receptor genes (ESR1 and ESR2) of round (RL) and uterosacral ligaments (USL) in postmenopausal women with uterine prolapse.

Study Design: Gene expressions of 32 postmenopausal women with prolapse were analysed according to gene expressions of 8 postmenopausal women without prolapse. Read More

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November 2018

Change in Lower Eyelid Position After Ptosis Repair in Patients With Unilateral Myogenic Versus Aponeurotic Blepharoptosiss.

Ophthalmic Plast Reconstr Surg 2018 Dec 7. Epub 2018 Dec 7.

Eye Research Center, Rassoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran.

Purpose: To compare preoperative and postoperative lower eyelid scleral show in patients with unilateral myogenic (MP) and aponeurotic (AP) ptosis, analyze the factors correlated with them, and assess the rate of postoperative lower eyelid symmetry in both groups.

Methods: Patients (older than 5 years old) with unilateral MP (58) and AP (20) were included from June 2015 to April 2017. Excluded were patients with previous eyelid surgery, strabismus, levator function of ≤3, and associated procedures. Read More

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December 2018
1 Read

Tetanus outbreak in a sheep flock due to ear tagging.

Vet Med Sci 2018 Dec 13. Epub 2018 Dec 13.

Department of Internal Medicine, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.

Tetanus is an acute, often fatal, infectious neuromuscular disease in all farmed mammals caused by Clostridium tetani. The disease is sporadic but outbreaks of tetanus have been described, as a result of wound contaminated with spores of C. tetani, which sporulates to the vegetative form and produce toxins. Read More

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December 2018

Implantation of a MitraClip between two previously implanted MitraClips to treat recurrent severe mitral regurgitation.

J Cardiol Cases 2017 Feb 17;15(2):50-52. Epub 2016 Nov 17.

Department of Cardiology, Deutsches Herzzentrum München, Technische Universität München, Munich, Germany.

We first describe the implantation of a MitraClip (Abbott Vascular, Abbott Park, IL, USA) between 2 previously implanted MitraClips to treat recurrent mitral regurgitation (MR). An 82-year-old male patient presented with dyspnea New York Heart Association NYHA class III due to recurrent severe MR 18 months after primarily successful implantation of 2 MitraClips. The initial procedure was performed to treat severe MR due to prolapse and flail of the anterior leaflet and resulted in mild MR after implantation of 2 MitraClips. Read More

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February 2017

Surgical repair of tricuspid regurgitation due to annular detachment caused by chest trauma.

J Cardiol Cases 2016 Sep 7;14(3):94-96. Epub 2016 Jun 7.

Department of Cardiovascular Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan.

Traumatic tricuspid valve regurgitation (TR) is a fairly rare complication of blunt chest trauma, and is usually caused by chordal and/or papillary muscle rupture. A 45-year-old woman, with a history of blunt chest trauma 16 years previously, was referred for surgery due to severe TR. During surgery, we found a large perforation on the right atrial wall located just anteriorly to the anterior leaflet, which was caused by annular detachment, in addition to anterior leaflet prolapse due to rupture of anterior chordae. Read More

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September 2016

An observation of massive lumbar disc prolapse.

J Spine Surg 2018 Sep;4(3):583-587

The Robert Jones and Agnes Hunt Orthopaedic Hospital NHS Foundation, Oswestry, Shropshire, UK.

Background: The aim of this study was to investigate whether massive lumbar disc herniations (LDH) can be managed safely with non-operative treatment. Whilst most LDH are treated successfully with analgesia and physiotherapy, there is little literature regarding the treatment of massive LDH. Their impressive size raises the suspicion that they may cause cauda equina syndrome and are therefore often treated surgically. Read More

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September 2018
2 Reads

A 17-Year-Old Boy With High-Functioning Autism, Gastrointestinal Illness, and Seizures.

Pediatrics 2018 Dec 13. Epub 2018 Dec 13.

Massachusetts General Hospital, Boston, Massachusetts; and

A healthy 17-year-old boy with a high-functioning pervasive developmental disorder presented to the emergency department after having a 4-minute episode of seizure-like activity in the setting of presumed viral gastroenteritis. Within an hour of emergency department arrival, he developed a forehead-sparing facial droop, right-sided ptosis, and expressive aphasia, prompting stroke team assessment and urgent neuroimaging. Laboratory results later revealed a serum sodium of 119 mmol/L. Read More

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December 2018
1 Read

Mid-urethral sling in the management of women with stress urinary incontinence after pelvic organ prolapse treatment.

Authors:
Peng-Hui Wang

Taiwan J Obstet Gynecol 2018 Dec;57(6):777-778

Department of Obstetrics and Gynecology, Taipei Veterans General Hospital, Taipei, Taiwan; Department of Obstetrics and Gynecology, National Yang-Ming University, Taipei, Taiwan; Institute of Clinical Medicine, National Yang-Ming University School of Medicine, Taipei, Taiwan; Department of Medical Research, China Medical University Hospital, Taichung, Taiwan. Electronic address:

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December 2018

Popcorn Capsulorrhaphy in Revision Aesthetic Breast Surgery.

Aesthet Surg J 2018 Dec 13. Epub 2018 Dec 13.

Private practice in Louisville, KY.

Background: Control of the pocket in revisional breast surgery can be technically challenging and unpredictable. A capsulorrhaphy technique has been utilized in altering capsules in secondary aesthetic breast surgery.

Objectives: The authors sought to determine the effectiveness of popcorn capsulorrhaphy in revisional breast surgery. Read More

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December 2018

Horner's Syndrome and Upper Extremity Weakness After Quadratus Lumborum Block for Postcesarean Section Analgesia: A Case Report.

A A Pract 2018 Dec 11. Epub 2018 Dec 11.

Boston University School of Medicine, Boston, Massachusetts.

A healthy, 34-year-old primigravida at 41 weeks gestational age presented for cesarean delivery due to a category 2 fetal heart tracing remote from delivery. After completion of the surgery under epidural anesthesia, bilateral quadratus lumborum blocks were performed for postoperative pain. Approximately 4 hours later, the patient developed left-sided arm weakness, left miosis, and ptosis. Read More

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December 2018

Mucosal Schwann Cell Hamartoma of the Rectosigmoid Junction: A Rare Lesion Mimicking Mucosal Prolapse Syndrome and Other Neural Lesions.

Int J Surg Pathol 2018 Dec 12:1066896918818897. Epub 2018 Dec 12.

1 NTT Medical Center Tokyo, Tokyo, Japan.

In this article, we report the case of a 40-year-old woman with a sessile polyp of the rectosigmoid junction that underwent endoscopic resection. The resected specimen showed spindle cell proliferation with eosinophilic cytoplasm between mucosal crypts, mimicking mucosal prolapse syndrome. However, these were immunohistochemically positive for S-100, indicating neural cell origin. Read More

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December 2018

Management of retrorectal hematoma after stapled transanal rectal resection for prolapsed hemorrhoids associated with occult rectal prolapse and obstructed defecation syndrome.

Tech Coloproctol 2018 Dec 6. Epub 2018 Dec 6.

AUSL della Romagna, Department of General Surgery, Ospedale per gli Infermi, Faenza, Italy.

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December 2018

Intermediate-term outcomes of our original multiple-knot technique using ePTFE sutures for anterior mitral leaflet prolapse.

Surg Today 2018 Dec 6. Epub 2018 Dec 6.

Department of Cardiovascular Surgery, Osaka Rosai Hospital, 1179-3, Nagasone-cho, Kita-ku, Sakai, Osaka, Japan.

Purpose: To define the outcomes of our original simple chordal replacement technique using ePTFE sutures for mitral regurgitation.

Methods: Between January, 2004 and March, 2014, 38 patients underwent mitral valve repair using our chordal replacement technique for anterior leaflet prolapse. The mitral regurgitation was caused by degenerative disease in 34 patients and infective endocarditis in 4 patients. Read More

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December 2018

Arrhythmic Mitral Valve Prolapse: JACC Review Topic of the Week.

J Am Coll Cardiol 2018 Dec;72(23 Pt A):2904-2914

Helmsley Electrophysiology Center, Icahn School of Medicine at Mount Sinai, New York, New York.

There is an increasing awareness of the association between mitral valve prolapse and sudden cardiac death. There are several clinical risk factors associated with an increased risk of mitral valve prolapse-related sudden cardiac death, most of which can be evaluated with noninvasive diagnostic modalities. For example, characteristic changes on the electrocardiogram (T-wave inversions in the inferior leads), complex ventricular ectopy, a spiked configuration of the lateral annular velocities by echocardiography, and evidence of myocardial fibrosis by cardiac magnetic resonance imaging have all been implicated as markers of risk. Read More

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December 2018

Berg adder (Bitis atropos) envenoming: an analysis of 14 cases.

Clin Toxicol (Phila) 2018 Dec 6:1-6. Epub 2018 Dec 6.

b Division of Pharmacology, Department of Medicine, Faculty of Medicine and Health Sciences, Tygerberg Poison Information Centre , Stellenbosch University , Cape Town , South Africa.

Introduction: The berg adder (Bitis atropos) is a little-studied, lesser-known viperid snake found in southern Africa and there is limited information available regarding the manifestations of envenoming.

Materials And Methods: This observational series of 14 cases documents features of berg adder envenoming over a period of 16 years (1987-2003). Clinical features of envenomed patients: All 14 patients developed local cytotoxic effects. Read More

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December 2018

Genome-wide association study of degenerative mitral valve disease in Maltese dogs.

J Vet Sci 2018 Dec 4. Epub 2018 Dec 4.

Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University, Seoul, 05030, Korea.

Genome-wide association study (GWAS) is a powerful tool for identifying the genetic causes of various diseases. This study conducted to identify genomic variation in Maltese dog genomes associated with degenerative mitral valve disease (DMVD) development and evaluate the association of each biological condition with DMVD in Maltese dogs. DNA was extracted from blood samples obtained from 48 Maltese dogs (32 with DMVD and 16 controls). Read More

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December 2018
2 Reads

Pediatric open-globe injury in a university-based tertiary hospital.

Eur J Ophthalmol 2018 Dec 12:1120672118818013. Epub 2018 Dec 12.

1 Department of Ophthalmology, King Abdulaziz University Hospital, College of Medicine, King Saud University, Riyadh, Saudi Arabia.

Background:: To investigate epidemiology, etiology, and outcomes after repair of pediatric open-globe injury.

Methods:: We retrospectively reviewed medical records of patients ⩽18 years who underwent primary open-globe repair.

Results:: A total of 213 patients were identified. Read More

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December 2018

Prevalence of metabolic syndrome and its components in women with and without pelvic organ prolapse and its association with prolapse severity according to the Pelvic Organ Prolapse Quantification system.

Int Urogynecol J 2018 Dec 12. Epub 2018 Dec 12.

Gynecology and Physiopathology of Human Reproduction, S. Orsola-Malpighi Hospital, Department of Medical and Surgical Sciences (DIMEC), University of Bologna, Via Massarenti, 9, 40138, Bologna, Italy.

Introduction And Hypothesis: Data regarding possible associations between metabolic syndrome (MS) and pelvic organ prolapse (POP) are scarce. The primary hypothesis was that the prevalence of MS and its components was higher in postmenopausal women with POP than in age-matched women without POP staged with the Pelvic Organ Prolapse Quantification system (POP-Q). The secondary aim of the study was to analyze the association between MS and its components with POP severity. Read More

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December 2018

Aortic regurgitation due to back-and-forth intimal flap movement detected by both multidetector computed tomography and transesophageal echocardiography.

J Cardiol Cases 2013 Jun 16;7(6):e161-e163. Epub 2013 Mar 16.

Division of Cardiology and Cardiovascular Surgery, Mitsui Memorial Hospital, 1 Kanda-Izumicho, Chiyoda-ku, Tokyo 101-8643, Japan.

A 46-year-old man with a history of hypertension, chronic kidney disease, and chronic aortic dissection classified as DeBakey type IIIB was referred to our hospital with chest and back pain. The patient underwent 64-row multidetector computed tomography (MDCT), which revealed new-onset DeBakey type II aortic dissection. The intimal flap prolapsed into left ventricle in the diastolic phase of cardiac cycle and stuck to the right coronary cusp (RCC) of the aortic valve. Read More

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Giant fenestration and fibrous strand rupture of aortic valve without massive regurgitation.

J Cardiol Cases 2012 Jun 11;5(3):e163-e165. Epub 2012 May 11.

Tokyo Heart Center, Department of Cardiovascular Surgery, Tokyo, Japan.

We present a case of a giant fenestration and a fibrous strand rupture of the aortic valve without massive regurgitation. A 56-year-old woman, was referred for coronary revascularization, had II-III degree aortic regurgitation without symptoms of heart failure. On the intraoperative direct view, the non coronary cusp (NCC) had the giant fenestration and the left coronary cusp (LCC) had the fibrous strand rupture. Read More

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The role of tenascin-X in the uterosacral ligaments of postmenopausal women with pelvic organ prolapse: an immunohistochemical study.

Int Urogynecol J 2018 Dec 10. Epub 2018 Dec 10.

Department of General Gynecology and Gynecologic Oncology, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria.

Introduction And Hypothesis: Abnormalities of connective tissue structure or its repair mechanism may predispose women to pelvic organ prolapse (POP). We hypothesized that the expression of tenascin-X in the uterosacral ligament of postmenopausal women with symptomatic POP is increased compared with postmenopausal women without POP. Furthermore, we identified clinical risk factors associated with POP in our study population. Read More

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December 2018

[The trend towards full-endoscopic decompression : Current possibilities and limitations in disc herniation and spinal stenosis].

Authors:
S Ruetten M Komp

Orthopade 2018 Dec 7. Epub 2018 Dec 7.

Zentrum für Wirbelsäulenchirurgie und Schmerztherapie, Zentrum für Orthopädie und Unfallchirurgie der St. Elisabeth Gruppe - Katholische Kliniken Rhein-Ruhr, St. Anna Hospital Herne/Universitätsklinikum, Marien Hospital Herne/Marien Hospital Witten, Hospitalstr. 19, 44649, Herne, Deutschland.

Background: The most frequent causes of degenerative constrictions of the spinal canal are disk herniations and spinal stenoses. The lumbar and cervical spine is the most affected.

Surgical Procedures: After conservative treatments have been exhausted, surgical intervention may be necessary. Read More

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December 2018
1 Read

[Cerebral ptosis. Analysis of six cases].

Rev Med Chil 2018 Aug;146(8):857-863

Departamento Ciencias Neurológicas, Facultad de Medicina, Universidad de Chile, Santiago, Chile.

Background: Cerebral ptosis is understood as the bilateral paralysis of eyelid elevation linked to a stroke or hemorrhage of the middle cerebral artery (MCA). It is a transient condition, independent of the evolution of the lesion.

Aim: To analyze six patients with the condition. Read More

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New Approach to Oncoplastic Breast Conservation: Combining Autologous Volume Replacement and the Wise-pattern Mammaplasty.

Plast Reconstr Surg Glob Open 2018 Oct 16;6(10):e1987. Epub 2018 Oct 16.

Georgia Breast Surgery, Lawrenceville, Ga.

Background: Oncoplastic breast-conserving surgery describes a set of techniques that allow for generous oncological resection with immediate tumor-specific reconstruction. These techniques are classically divided into either volume displacement (local breast flaps and or reduction mammaplasty/mastopexy strategies) versus volume replacement strategies (transfer of autologous nonbreast tissue from a local or distant site and, less commonly, implant placement). There have been few descriptions of merging these 2 classical approaches to facilitate breast-conserving surgery. Read More

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October 2018

Synchronous Surgical Treatment of Lower Eyelid Involutional Entropion and Ptosis.

Case Rep Ophthalmol Med 2018 11;2018:2478646. Epub 2018 Nov 11.

424 General Military Training Hospital of Thessaloniki, Thessaloniki, Greece.

Background: Involutional entropion and upper eyelid ptosis are common eyelid diseases in the elderly population. They represent a frequent cause of discomfort and often result in significant visual and functional impairment. The surgical management of these disorders includes various treatment options and techniques and is usually carried out in multiple time sessions. Read More

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November 2018

An epidemiologic study on symptomatic pelvic organ prolapse in obese Chinese women: a population-based study in China.

Diabetes Metab Syndr Obes 2018 16;11:761-766. Epub 2018 Nov 16.

Department of Gynecology and Obstetrics, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, People's Republic of China,

Background: The aim of this study was to investigate the prevalence and risk factors of symptomatic pelvic organ prolapse in obese Chinese women.

Subjects And Methods: We performed a secondary analysis of 3,105 obese women from an observational cross-sectional study conducted between February 2014 and March 2016 in Mainland China. The obesity standard in our study was the Chinese standard (body mass index ≥28). Read More

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November 2018

Intraoperative disc prolapse during percutaneous endoscopic lumbar discectomy.

World Neurosurg 2018 Dec 6. Epub 2018 Dec 6.

Department of Neurosurgery, The Leon Wiltse Memorial Hospital, Suwon, Korea.

Background: Percutaneous endoscopic lumbar discectomy (PELD) has become popular and is regarded as an alternative treatment for lumbar disc herniation (LDH). Although the indication has expanded with remarkable evolution of the technique, sometimes unexpected experiences have been faced during PELD. De novo disc prolapse was reported for the first time during the PELD. Read More

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December 2018
1 Read

Prevalence and Awareness of Pelvic Floor Disorders in Adolescent Females Seeking Gynecologic Care.

J Pediatr Adolesc Gynecol 2018 Dec 5. Epub 2018 Dec 5.

Department of Obstetrics and Gynecology, University of Alabama at Birmingham, Birmingham, Alabama.

Objective: To determine the prevalence and awareness of pelvic floor disorder (PFD) symptoms among adolescent females.

Design: Cross-sectional study via a written, anonymous survey of adolescents. The survey was composed of validated measures for determination of symptom prevalence. Read More

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December 2018

Epiglottopexy by external puncture for epiglottic prolapse in severe laryngomalacia. A novel technique.

Eur Ann Otorhinolaryngol Head Neck Dis 2018 Dec 4. Epub 2018 Dec 4.

Department of pediatric thoracic surgery, Hospital Infantil de México, Federico Gómez, Mexico.

Introduction: Laryngomalacia (LM) is the first cause of stridor in infants. 10 to 20% of patients with LM may require surgery due to the development of severe symptoms. Supraglottoplasty is the most commonly performed surgery for severe LM. Read More

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December 2018

Systematic review of outcomes and complications in nonimplant-based mastopexy surgery.

J Plast Reconstr Aesthet Surg 2018 Nov 9. Epub 2018 Nov 9.

Department of Plastic, Reconstructive and Aesthetic Surgery, Lausanne University Hospital, Lausanne, Switzerland.

Background: Mastopexy is one of the most performed cosmetic surgery procedures in the U.S. Numerous studies on mastopexy techniques have been published in the past decades, including case reports, retrospective reviews, and prospective studies. Read More

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November 2018

Should We Always Use Antibiotics after Urodynamic Studies in High-Risk Patients?

Biomed Res Int 2018 5;2018:1607425. Epub 2018 Nov 5.

2nd Department of Gynaecology, Medical University of Lublin, Lublin, Poland.

Aim: The aim of this observational study was to evaluate the effectiveness of a phytotherapic drug (Canephron N) in preventing urinary tract infection (UTI) in high-risk women undergoing urodynamic studies (UDS).

Methods: The study protocol was approved by the local institutional ethical committee. Adult women with at least one risk factor for acquiring UTI (defined as: age over 70, elevated postvoid residual urine>100 ml, recurrent UTI, pelvic organ prolapse (POP) ≥II in POP-Q scale, and neurogenic bladder) had received after UDS either a single oral dose of fosfomycin trometamol (FT) (3 grams) or a phytodrug containing centaury herb, lovage root, and rosemary leaves (5 ml taken orally three times daily for one week). Read More

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November 2018
3 Reads

Efficacy of mace (Arils of Houtt) plus PFMT on symptoms in mixed urinary incontinence: a randomized placebo-controlled trial.

Integr Med Res 2018 Dec 26;7(4):307-315. Epub 2018 Oct 26.

Department of Amraze Niswan wa Ilmul Qabalat (Gynecology and Obstetrics), National Institute of Unani Medicine, Bengaluru, India.

Background: It is not only to evaluate the efficacy and safety of mace (Arils of Houtt) but also to compare pelvic floor muscle training vs. pelvic floor muscle training (PFMT) for improving symptoms and health-related quality of life (HRQoL) of woman with mixed urinary incontinence (MUI).

Methods: A prospective, single-blind randomized controlled study was conducted. Read More

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December 2018
2 Reads

Horner Syndrome Due to Spontaneous Internal Carotid Artery Dissection.

Cureus 2018 Sep 28;10(9):e3382. Epub 2018 Sep 28.

Neurology, University of Missouri, Columbia, USA.

Horner syndrome is a constellation of neurological findings consisting of ipsilateral ptosis, miosis, and anhidrosis. Partial Horner syndrome, comprising ipsilateral ptosis and miosis in the absence of anhidrosis, is a well-documented but uncommon manifestation of internal carotid artery dissection. We report the case of a 42-year-old male patient who presented with ipsilateral ptosis and miosis and was subsequently diagnosed with internal carotid artery dissection. Read More

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September 2018
1 Read

Review of Ocular Manifestations of Joubert Syndrome.

Genes (Basel) 2018 Dec 4;9(12). Epub 2018 Dec 4.

Department of Ophthalmology, Stanford University School of Medicine, 1651 Page Mill Road, Palo Alto, CA 94305, USA.

Joubert syndrome is a group of rare disorders that stem from defects in a sensory organelle, the primary cilia. Affected patients often present with disorders involving multiple organ systems, including the brain, eyes, and kidneys. Common symptoms include breathing abnormalities, mental developmental delays, loss of voluntary muscle coordination, and abnormal eye movements, with a diagnostic "molar tooth" sign observed by magnetic resonance imaging (MRI) of the midbrain. Read More

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December 2018
2 Reads

Type of pelvic disease as a risk factor for surgical site infection in women undergoing hysterectomy.

J Minim Invasive Gynecol 2018 Nov 30. Epub 2018 Nov 30.

The Ottawa Hospital Research Institute, 725 Parkdale Avenue, Ottawa ON, K1Y 4E9.

Study Objective: To quantify the relationship between type of benign pelvic disease and risk of surgical site infection (SSI) after hysterectomy DESIGN: Retrospective Cohort (Classification II-2) SETTING: Hospitals participating in the American College of Surgeons National Surgical Quality Improvement Program (NSQIP) PATIENT(S): Women who underwent hysterectomy from 2006-2015 and recorded in NSQIP database INTERVENTION: None MEASUREMENTS AND MAIN RESULTS: SSI risk was compared for type of benign pelvic diseases, patient characteristics (age, race and selected comorbidities) and process of care variables (admission status, type of hysterectomy, and operative time). Among a total of 125,337 women who underwent hysterectomy, 2.48% developed SSI. Read More

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November 2018
1 Read

Anterior and middle pelvic organ prolapse repair using a six tension-free strap low weight transvaginal mesh: long-term retrospective monocentric study of 311 patients.

J Gynecol Obstet Hum Reprod 2018 Nov 30. Epub 2018 Nov 30.

Hôpital Privé Sainte Marie, Groupe Ramsay General de Sante, Chalon sur Saône, France. Electronic address:

Introduction: Treatment of pelvic organ prolapse is an important public health issue due to the ageing population. The Food and Drug Administration, in 2011, issued a warning on complications after transvaginal insertion of high weight mesh. We evaluated a 6 tension-free straps, light prosthesis made from polypropylene monofilaments. Read More

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November 2018
1 Read

Cognitive changes in older women after urogynaecological surgery.

Ginekol Pol 2018 ;89(11):587-592

Frauenzimmer Bern AG, Bern, Switzerland.

Objectives: The need for pelvic floor surgery will increase with an aging population in the future. Aim of this prospective study was to evaluate the evolution of cognitive function in elderly women after urogynaecological surgery.

Material And Methods: Between 2010 and 2014, 51 female patients 70 years and older who underwent urogynaecological surgery participated in this study. Read More

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January 2018
1 Read

Prospective evaluation of paravaginal defect repair with and without apical suspension: a 6-month postoperative follow-up with MRI, clinical examination, and questionnaires.

Int Urogynecol J 2018 Dec 1. Epub 2018 Dec 1.

Department of Obstetrics and Gynaecology, Aarhus University Hospital, Aarhus, Denmark.

Introduction And Hypothesis: Paravaginal defect (PVD) has been suggested as one of the main contributors to the development of prolapse in the anterior vaginal wall (AVW). We aimed to evaluate the descent of pelvic organs, presence of vaginal H configuration, and pubococcygeus (PC) muscle defect by pelvic magnetic resonance imaging (MRI), together with subjective symptoms of prolapse, before and 6 months after PVD repair. We also aimed to evaluate risk factors of recurrence. Read More

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December 2018
1 Read

Exposure, entropion, and bilateral corneal ulceration in a newborn as a manifestation of chromosome 22 q11.2 duplication syndrome.

Am J Ophthalmol Case Rep 2019 Mar 4;13:16-19. Epub 2018 Nov 4.

Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Boston, MA, USA.

Purpose: Chromosome 22q11.2 micro-duplication syndrome (MDS), is a rare autosomal dominant condition, with a highly variable phenotype that ranges from unremarkable and asymptomatic, to fatal due to cardiovascular defects. Hypertelorism, downslanting palpebral fissures, superior displacement of the eyebrows, and ptosis are the most commonly reported ocular manifestations. Read More

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March 2019
1 Read

Hypoxia-Inducible Factor 1-α (HIF-1α) Induces Apoptosis of Human Uterosacral Ligament Fibroblasts Through the Death Receptor and Mitochondrial Pathways.

Med Sci Monit 2018 Dec 3;24:8722-8733. Epub 2018 Dec 3.

Department of Obstetrics and Gynecology, Qilu Hospital of Shandong University, Jinan, Shandong, China (mainland).

BACKGROUND Hypoxia induces cell apoptosis in the uterosacral ligaments of patients with pelvic organ prolapse by upregulation of hypoxia-inducible factor-1α (HIF-1α). This study aimed to investigate the effects of HIF-1α on human uterosacral ligament fibroblasts (hUSLFs) following treatment with the chemical inducer of hypoxia, cobalt chloride (CoCl2), and to explore the underlying mechanisms. MATERIAL AND METHODS Ten women who underwent hysterectomy for benign disease provided uterosacral ligament tissue for cell extraction. Read More

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December 2018
2 Reads

[How I do… easily a vaginal sacrospinous colpopexy using an isthmic posterior mesh].

Gynecol Obstet Fertil Senol 2018 Nov 29. Epub 2018 Nov 29.

Département de gynécologie, hospices civils de Lyon, hôpital Femme-Mère-Enfant, HFME, 59, boulevard Pinel, 69000 Lyon, France.

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November 2018
2 Reads

Retrobulbar anaesthesia for adjustable strabismus surgery in adults: a prospective observational study.

Can J Ophthalmol 2018 Dec 5;53(6):621-626. Epub 2018 Apr 5.

Department of Ophthalmology, McGill University, Montréal, Qué.

Objective: To characterize the ocular response to retrobulbar anaesthesia and to evaluate the efficacy of retrobulbar anaesthesia for adjustable strabismus surgery in adults.

Design: Prospective observational study.

Participants: Adult patients undergoing adjustable strabismus surgery under retrobulbar anaesthesia. Read More

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December 2018
1 Read

Mycobacterium genavense Infection in a Domestic Ferret (Mustela putorius furo).

Top Companion Anim Med 2018 Dec 10;33(4):119-121. Epub 2018 Oct 10.

Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna (IZSLER), 25124 Brescia, Italy.

Mycobacterium genavense infection was diagnosed in an adult ferret with ptosis of the left eye, a proliferative lesion of the conjunctiva of the nictitating membrane, conjunctival swelling, and tumefaction of the periorbital tissues with a watery ocular discharge and the presence of a retrobulbar mass. The diagnosis was based on characteristic cytology of the retrobulbar mass and left mandibular lymph node that revealed granulomatous inflammation. Ziehl-Neelsen staining showed the presence of positive acid-fast bacilli in the cytoplasm of the macrophages. Read More

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December 2018
1 Read

Proteomics of Uterosacral Ligament Connective Tissue from Women With and Without Pelvic Organ Prolapse.

Proteomics Clin Appl 2018 Dec 5:e1800086. Epub 2018 Dec 5.

The Key Laboratory of Reproductive Genetics (Zhejiang University), Ministry of Education, Hangzhou, China.

Purpose: Damage to the uterosacral ligaments is an important contributor to uterine and vaginal prolapse. The aim of this study was to identify differentially expressed proteins in the uterosacral ligaments of women with and without pelvic organ prolapse and analyze their relationships to cellular mechanisms involved in the pathogenesis of pelvic organ prolapse.

Experimental Design: Uterosacral ligament connective tissue from four patients with pelvic organ prolapse and four control women underwent iTRAQ analysis followed by Ingenuity Pathway Analysis of differentially expressed proteins. Read More

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December 2018
1 Read

Treatment of vaginal vault prolapse in The Netherlands: a clinical practice survey.

Int Urogynecol J 2018 Dec 4. Epub 2018 Dec 4.

Department of Gynaecology and Obstetrics, Máxima Medical Centre, De Run 4600, 5500 MB, Veldhoven, The Netherlands.

Introduction And Hypothesis: A great variety of conservative and surgical procedures to correct vaginal vault prolapse have been reported. The aim of this study was to describe practice pattern variation-the difference in care that cannot be explained by the underlying medical condition-among Dutch gynecologists regarding treatment of vaginal vault prolapse.

Methods: A clinical practice survey was conducted from March to April 2017. Read More

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December 2018
6 Reads

Solitary rectal ulcer syndrome complicating sessile serrated adenoma/polyps: A case report and review of literature.

World J Clin Cases 2018 Nov;6(14):820-824

Department of Pathology, Fudan University Shanghai Cancer Center, Shanghai 200032, China.

Solitary rectal ulcer syndrome (SRUS) is a rare benign condition, which can mimic many other diseases because of their similarities in clinical, endoscopic and histological features. Sessile serrated adenoma/polyp (SSA/p) is a premalignant lesion in the colon and rectum. The misdiagnosis of SSA/p in SRUS patients has been noted, but the case of SRUS arising secondarily to SSA/p has been rarely reported. Read More

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November 2018
2 Reads

The Eye Opener: Finding and Targeting the Midbrain Lesion.

Neuroophthalmology 2018 Oct 9;42(5):316-317. Epub 2018 Jan 9.

Department of Neurology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

Lesions of the central nucleus of the third cranial nerve in midbrain leads to bilateral ptosis. We present a case of a 14 year old boy, who was found to have B/L non-correctable ptosis and medial rectus palsy. There was a ring enhancing lesion in the midbrain in contrast MRI which resolved with treatment. Read More

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October 2018
2 Reads

Effects of Stapled Hemorrhoidopexy on Anorectal Function: A Prospective Randomized Controlled Trial.

Iran J Med Sci 2018 Nov;43(6):581-586

Colorectal Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.

Background: Stapled hemorrhoidopexy is a safe and acceptable alternative to traditional hemorrhoidectomy with shorter hospital stay, better satisfaction, and less postoperative pain. There have, however, been reports on early and late complications. Therefore, the present study was designed to assess the impact of stapled hemorrhoidopexy on anorectal function and continence. Read More

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November 2018
2 Reads

Infective endocarditis complicated with nonobstructive ST elevation myocardial infarction related to septic embolism with intracranial hemorrhage: A case report.

Medicine (Baltimore) 2018 Nov;97(48):e13089

Division of Cardiology, Department of Internal Medicine, Kaohsiung Medical University Hospital.

Rationale: Infective endocarditis (IE) complicated with obstructive ST elevation myocardial infarction (STEMI) has been reported in the literature and which were mostly related to coronary artery embolism, obstruction, or compression. However, there has been no reported case discussing about IE complicated with nonobstructive STEMI.

Patient Concerns: In this report, we report a 38-year-old female suffering from intermittent fever and was later diagnosed as IE. Read More

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November 2018
4 Reads

Meshes in a mess: Mesenchymal stem cell-based therapies for soft tissue reinforcement.

Acta Biomater 2018 Nov 27. Epub 2018 Nov 27.

Stem Cell Therapy Unit, Jesús Usón Minimally Invasive Surgery Centre, Ctra. N-521, km 41.8, 10071 Cáceres, Spain; CIBER de Enfermedades Cardiovasculares, Avenida Monforte de Lemos, 3-5. Pabellón 11. Planta 0, 28029 Madrid, Spain.

Surgical meshes are frequently used for the treatment of abdominal hernias, pelvic organ prolapse, and stress urinary incontinence. Though these meshes are designed for tissue reinforcement, many complications have been reported. Both differentiated cell- and mesenchymal stem cell-based therapies have become attractive tools to improve their biocompatibility and tissue integration, minimizing adverse inflammatory reactions. Read More

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November 2018
4 Reads