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Eur J Ophthalmol 2021 Jun 10:11206721211024821. Epub 2021 Jun 10.

Department of Ophthalmology, Rio Hortega University Hospital, Valladolid, Spain.

Introduction: Neuromuscular choristoma (NC) is a rare tumor composed of striated muscle fibers admixed with nerve fibers that often affects large peripheral nerve trunks in children. To the best of our knowledge, this is the first reported case in the literature of a NC of the ophthalmic nerve in an adult.

Case Description: A 27-year-old woman presented with a 20-day history of left periorbital headache radiating to the frontotemporal region, with associated tearing, nausea, and vomiting. Read More

Braz J Biol 2021 4;82:e237869. Epub 2021 Jun 4.

The University of the West Indies - UWI, Faculty of Food and Agriculture - FFA, Department of Food Production - DFP, The Open Tropical Forage-Animal Production Laboratory - OTF-APL, St. Augustine, Trinidad and Tobago.

Reproductive diseases have been well documented in domestic livestock such as sheep, goat, cattle and pigs. However, there is very little information on these diseases in the agouti (Dasyprocta leporina). The agouti is used for its meat in South America and the Caribbean. Read More

Cureus 2021 May 4;13(5):e14839. Epub 2021 May 4.

College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Jeddah, SAU.

The concomitance between Parkinson's disease (PD) and myasthenia gravis (MG) is rare, with only a few case reports in the literature and only one of them with positive anti-muscle specific kinase (anti-MuSK) MG. The overlap between PD and MG symptoms can cause a diagnostic dilemma for the treating physician. In this report, we present a 73-year-old lady with a history of recurrent falls, dysphagia, and diplopia. Read More

BMC Surg 2021 Jun 5;21(1):284. Epub 2021 Jun 5.

Shanxi Bethune Hospital, Taiyuan, 030012, People's Republic of China.

Background: Full-thickness rectal prolapse (FTRP) frequently occurs in elderly women, and more than 100 surgical procedures have been proposed to restore FTRP. The Gant-Miwa-Thiersch (GMT) procedure is the most used treatment in China. However, the recurrence rate of FTRP post-GMT, which is as high as 23. Read More

Arch Esp Urol 2021 Jun;74(5):494-502

Servicio de Urología. Hospital Nacional de Parapléjicos. Toledo. España.

Objectives: To analyse the outcomes of Robotic Sacrocolpopexy (RSC) on resolution of Lower urinary tract Symptoms (LUTS) associated to pelvic organ prolapses (POP) and to determine the risk factors for preoperative LUTS presence.

Material And Methods: A longitudinal study was carried out on 51 females mean aged (± standard deviation) 66 ± 9 years, who underwent RSC. A preoperative evaluation was made on the degree and type of POP, and the presence of the LUTS stress urinary incontinence (SUI), urgency and voiding difficulty. Read More

BMJ Case Rep 2021 May 31;14(5). Epub 2021 May 31.

Department of Medicine for the Elderly, Luton and Dunstable University Hospital NHS Foundation Trust, Luton, UK.

An 84-year-old man presented with a frontal headache and easy bruising. He had a background history of a pituitary macroadenoma, diagnosed incidentally a year earlier. Investigations showed haemorrhage into the pituitary macroadenoma leading to a diagnosis of pituitary apoplexy in the context of low platelet count secondary to immune thrombocytopaenia. Read More

J Minim Access Surg 2021 May 11. Epub 2021 May 11.

Department of Surgical Gastroenterology, GEM Hospital and Research Centre, Coimbatore, Tamil Nadu, India.

Background: Rectal prolapse is more common in elderly women worldwide, but in India, it predominantly occurs in young- and middle-aged males. While ventral mesh rectopexy is proposed as the preferred procedure in females, the debate on the best procedure in men is still wide open.

Methods: A retrospective review of all adult male patients operated for external rectal prolapse (ERP) between January 2005 and December 2019 was performed. Read More

BMC Ophthalmol 2021 May 27;21(1):237. Epub 2021 May 27.

Department of Ophthalmology, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine, 158, Paryong-ro, Masanhoewon-gu, 51353, Changwon, Korea.

Background: The objective of this study was to investigate the clinical features and outcomes of Tolosa-Hunt syndrome (THS).

Methods: A retrospective review of the medical records was performed on patients with THS between March 2016 and January 2020. A total of eleven patients fulfilling the International Classification of Headache Disorders (ICHD-3 beta) diagnostic criteria for THS were included in this study. Read More

Zhonghua Fu Chan Ke Za Zhi 2021 May;56(5):341-348

Department of Gynecology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.

To investigate the occurrence and influencing factors of perioperative complications after robotic gynecologic surgery. The clinical data and occurrence of perioperative complications in 1 000 cases robotic surgery completed in the First Affiliated Hospital of Zhengzhou University were retrospectively analyzed. (1) Clinical data: the average age of the patients was (50. Read More

Medicine (Baltimore) 2021 May;100(21):e26148

Department of Cardiothoracic and Vascular Surgery, Kepler University Hospital, Medical Faculty, Johannes Kepler University, Linz, Austria.

Rationale: Redo surgeries after mitral valve repair are technically demanding. Procedures applying the NeoChord device (NeoChord Inc, St. Louis Park, MN) have proven to be safe and feasible in selected patients requiring mitral valve repair due to a leaflet prolapse or flail. Read More

Ann Med Surg (Lond) 2021 Jun 29;66:102346. Epub 2021 Apr 29.

Faculty of Medicine and Pharmacy, Hassan II University of Casablanca, B.P 5696, Casablanca, Morocco.

The etiologies of unilateral exophthalmos are multiple, rarely represented by an intra- or extra-conical vascular mass. Orbito-palpebral varixes are rare (2% of orbital masses) and represent a main cause of unilateral intermittent exophthalmos, often of an inflammatory nature. We report a Case of right orbito-palpebral varix in a 65-year-old adult, with no particular history, evolving for 2 years. Read More

BMJ Case Rep 2021 May 21;14(5). Epub 2021 May 21.

Internal Medicine Department, Hospital Garcia de Orta, Almada, Portugal

An 88-year-old male patient presented with left ptosis, diplopia, muscle weakness of the lower limbs, dysphagia for solids, dysphonia and constipation. On investigation, he was found to have myasthenia gravis (MG). Further evaluation for the possible cause of MG, with CT scan, revealed that the patient had concomitant prostatic cancer. Read More

Br J Haematol 2021 May 21. Epub 2021 May 21.

National Institute of Neurological Disorders and Stroke, Bethesda, MD, USA.

Reproductive health may be adversely impacted in women with dyskeratosis congenita (DC) and related telomere biology disorders (TBD). We evaluated gynaecological problems, fertility, and pregnancy outcomes in 39 females aged 10-81 years who were followed longitudinally in our DC/TBD cohort. Twenty-six had bone marrow failure and 12 underwent haematopoietic cell transplantation. Read More

Medicine (Baltimore) 2021 May;100(20):e25997

Shengli Clinical Medical College of Fujian Medical University.

Abstract: Levator ani defect (LAD) closely correlates with pelvic organ prolapse. This study aimed to compare the LAD grading between 3-dimensional ultrasonography (3D-US) and magnetic resonance imaging (MRI) and investigate the reasons for the difference using 3-dimensional pelvic models.Seventy-two Chinese women who were to undergo repair surgery were assessed by the prolapse staging, 3D-US and MRI. Read More

Female Pelvic Med Reconstr Surg 2021 Apr 7. Epub 2021 Apr 7.

From the Department of Obstetrics and Gynecology, School of Medicine and Dentistry, University of Rochester, Rochester, NY Department of Obstetrics and Gynecology, The Women's Hospital, Deaconess Health System, Newburgh, IN Department of Biostatistics and Computational Biology, School of Medicine and Dentistry, University of Rochester, Rochester, NY Department of Obstetrics and Gynecology, Duke University Medical Center, Durham, NC Western New York Urology Associates, Cheektowaga, NY Department of Obstetrics and Gynecology, The University of Texas Medical Branch, Galveston, TX.

Objective: The objective of this study is to characterize an acceptable health state, using the patient acceptable symptom state (PASS) question, in adult women with urinary incontinence.

Methods: This is a prospective multicenter cohort study determining PASS thresholds from condition-specific measures using an electronic research platform in English-speaking women seeking nonsurgical treatment of urinary incontinence between March 2019 and May 2020. Exclusions included pregnancy, isolated overactive bladder, and pelvic organ prolapse greater than stage II. Read More

BMC Infect Dis 2021 May 18;21(1):447. Epub 2021 May 18.

Department of Respiratory Medicine, Anjo Kosei Hospital, Anjo-cho Higashi-Hirokute 28, Anjo City, Aichi Prefecture, Japan.

Background: Enterococcus casseliflavus is rarely isolated from human specimens. To the best of our knowledge, there are no reports on its detailed treatment course and prognosis. Here, we present the first known case of E. Read More

Ophthalmol Retina 2021 May 14. Epub 2021 May 14.

Department of ocular oncology, Institut Curie, Paris, France; Université de Paris, Paris, France.

Purpose: To prospectively determine the efficacy and assess potential side effects of melphalan selective ophthalmic artery chemotherapy (SOAC) as first-line treatment for unilateral retinoblastoma.

Design: Phase II non-randomized prospective study.

Subjects: Patients with unilateral retinoblastoma group B, C or D of the International Classification for Intraocular Retinoblastoma (IRC). Read More

Prim Care Companion CNS Disord 2021 04 8;23(2). Epub 2021 Apr 8.

Maltepe University, Faculty of Medicine, Department of Neurology, Istanbul, Turkey.

BMJ Case Rep 2021 May 10;14(5). Epub 2021 May 10.

Department of Neurosurgery, Tallahassee Neurological Clinic, Tallahassee, Florida, USA.

A 28-year-old man in 2004 was identified with a spontaneous pseudoaneurysm and distal left cervical internal carotid artery (ICA) dissection. The patient was followed conservatively for 12 years with cross-sectional imaging. The patient was initially diagnosed with an acute left ICA dissection, with significant luminal narrowing. Read More

J Orthop Sports Phys Ther 2021 May 10:1-54. Epub 2021 May 10.

Department of Physiotherapy, Monash University, Melbourne, Australia.

Objective: To (i) review the effect of pelvic floor (PF) symptoms (urinary incontinence [UI], pelvic organ prolapse [POP], anal incontinence [AI]) on exercise participation in women, and (ii) explore PF symptoms as a barrier to exercising.

Design: Mixed-methods systematic review with meta-analysis.

Literature Search: Eight databases systematically searched to September 2020. Read More

BMJ Case Rep 2021 May 6;14(5). Epub 2021 May 6.

Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ontario, Canada

A 49-year-old man presented with new onset headache and diplopia, with right ptosis and limitation of extraocular movements consistent with a third nerve palsy. He had a known diagnosis of a non-functioning pituitary adenoma, and his presentation and neuroimaging were consistent with ischaemic pituitary apoplexy. The patient was otherwise stable with no signs of optic neuropathy or endocrine abnormality. Read More

Aesthet Surg J 2021 May 4. Epub 2021 May 4.

Background: PrabotulinumtoxinA is a 900-kDa botulinum toxin type A produced by Clostridium botulinum.

Objectives: The authors sought to investigate the safety of prabotulinumtoxinA for treatment of glabellar lines.

Methods: This was a multicenter, open-label, repeat-dose, 1-year phase II safety study. Read More

Aesthet Surg J 2021 May 4. Epub 2021 May 4.

Background: PrabotulinumtoxinA is a 900-kDa botulinum toxin type A produced by Clostridium botulinum.

Objectives: The authors sought to investigate the safety of prabotulinumtoxinA for treatment of glabellar lines.

Methods: This was a multicenter, open-label, repeat-dose, 1-year phase II safety study. Read More

Orv Hetil 2021 05 2;162(18):705-711. Epub 2021 May 2.

1 Semmelweis Egyetem, Általános Orvostudományi Kar, Szemészeti Klinika, Budapest, Mária utca 39., 1085.

Összefoglaló. Bevezetés: Szemhéjcsüngésnek (ptosis vagy blepharoptosis) nevezzük azt az állapotot, amikor a felső szemhéj abnormálisan alacsony pozícióban van. A szemhéjcsüngésnek lehetnek veleszületett és szerzett formái. Read More

Int J Cardiol 2021 Jul 29;334:154-156. Epub 2021 Apr 29.

Section of Cardiovascular Imaging, Heart, Vascular and Thoracic Institute, Cleveland Clinic, OH, United States. Electronic address:

Background: Mitral annular disjunction (MAD) is an increasingly recognized entity associated with mitral valve prolapse (MVP), ventricular arrhythmias and death. Few studies have investigated the utility of myocardial deformation analysis in MAD. We compared chamber quantification including strain by transthoracic echocardiography (TTE) and cardiac magnetic resonance imaging (CMR) between MVP patients with and without MAD. Read More

J Med Case Rep 2021 Apr 30;15(1):244. Epub 2021 Apr 30.

Department of Neurology, Changhua Christian Hospital, No. 135, Nanxiao Street, Changhua, 500, Taiwan.

Introduction: Pembrolizumab and other immune checkpoint inhibitors are the emerging treatment for selected, high-grade malignancies. However, a small number of patients are unable to tolerate its adverse effects, leading to discontinuation of this potentially life-changing therapy. In this study, we present a case of high-grade urothelial carcinoma patient, who experienced neurocomplications during the first pembrolizumab administration. Read More

Medicina (Kaunas) 2021 Apr 9;57(4). Epub 2021 Apr 9.

Department of Obstetrics and Gynecology, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro 43-gil, Songpa-gu, Seoul 05505, Korea.

Klippel-Trénaunay Syndrome (KTS) is a genetic vascular malformation involving the capillary, lymphatic, and venous channels. Prenatal sonographic diagnosis of KTS with an enlarged fetal limb is well-known; however, postnatal gynecologic manifestations are rarely reported. KTS can cause clitoromegaly, vulvovaginal hemangioma, and heavy menstrual bleeding. Read More

Am J Case Rep 2021 Apr 29;22:e931359. Epub 2021 Apr 29.

Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel.

BACKGROUND Systolic anterior motion (SAM) is the dynamic anteriorly directed movement of the anterior mitral valve leaflet during systole toward the left ventricular outflow tract (LVOT). The history of SAM in progressive hypertrophic cardiomyopathy (HCM) is unclear. It is believed that SAM is an irreversible process that progresses as the gradient over the LVOT increases. Read More

Indian J Ophthalmol 2021 05;69(5):1161-1166

Orbit, Oculoplasty, Reconstructive and Aesthetic Services, Sankara Nethralaya, Medical Research Foundation, Chennai, Tamil Nadu, India.

Purpose: The aim of this work was to study the clinical presentation, management and outcomes of orbital and adnexal amyloidosis.

Methods: This retrospective analysis included all the patients diagnosed with orbital and adnexal amyloidosis between January 1990 and December 2019. Positive staining with Congo Red and apple-green birefringence on polarized light microscopy established the diagnosis. Read More

BMJ Case Rep 2021 Apr 27;14(4). Epub 2021 Apr 27.

General Medicine, Nitte University K S Hegde Medical Academy, Mangalore, Karnataka, India.

A middle-aged woman with diabetes presented with left-sided facial pain, complete ptosis and fever of short duration. On presentation, she had hyperglycaemia without ketosis. There was total ophthalmoplegia of the left eye with a visual acuity of 6/36. Read More