20,398 results match your criteria Psychosomatic medicine[Journal]


Updated Sniffin' Sticks normative data based on an extended sample of 9139 subjects.

Eur Arch Otorhinolaryngol 2018 Dec 15. Epub 2018 Dec 15.

Department of Otorhinolaryngology, Smell and Taste Clinic, Technische Universität Dresden, Fetscherstraße 74, 01307, Dresden, Germany.

Purpose: To provide up-to-date and detailed normative data based on a large-scale sample, increasing diagnostic validity by reference to narrow age groups as previous normative values were based upon smaller sample sizes-especially in the group of older subjects.

Method: Data were obtained from 9139 healthy subjects (4928 females aged 5-96 years and 4211 males aged 5-91 years). The standard "Sniffin' Sticks" test was applied, comprising threshold (T), discrimination (D) and identification (I) subtests, and yielding a TDI sum score. Read More

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December 2018

The Relationship between Weight Status and Depressive Symptoms in a Population Sample with Obesity: The Mediating Role of Appearance Evaluation.

Obes Facts 2018 Dec 14;11(6):514-523. Epub 2018 Dec 14.

Integrated Research and Treatment Center (IFB) AdiposityDiseases, University Hospital Leipzig, Leipzig, Germany.

Objectives: Identifying the underlying pathways between obesity and depression and which individuals with obesity are at risk for developing depressive symptoms is important for improving prevention and treatment efforts. The current study investigated appearance evaluation as a potential mediator of the relationship between obesity and depression.

Methods: A total of 1,000 participants with a self-reported BMI greater than 30 kg/m2 were interviewed about their experiences with an elevated body weight and completed measures on appearance evaluation and depression. Read More

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December 2018

Out of control? Acting out anger is associated with deficient prefrontal emotional action control in male patients with borderline personality disorder.

Neuropharmacology 2018 Dec 13. Epub 2018 Dec 13.

Wellcome Centre for Integrative Neuroimaging, FMRIB, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.

Difficulty in anger control and anger-related aggressive outbursts against others are frequently reported by patients with borderline personality disorder (BPD). Although male sex is a known predictor for aggression, hardly any study has addressed the neural correlates of deficient anger control in male patients with BPD. Building on previous reports in female BPD, we investigated the involvement of lateral antero- and dorsal prefrontal cortex in the control of fast emotional actions and its relation to self-reported tendencies to act out anger. Read More

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December 2018

Patterns of altered regional brain glucose metabolism in borderline personality disorder and bipolar II disorder.

Acta Psychiatr Scand 2018 Dec 15. Epub 2018 Dec 15.

Institute of Clinical Medicine, University of Oslo, Norway.

Objective: The relationship between borderline personality disorder (BPD) and bipolar II disorder (BIP-II) is disputed but understudied. Here, we investigated brain glucose metabolism in these patient groups and healthy control subjects (HCs).

Methods: Sixty-five subjects, 22 BPD (19 females); 22 BIP-II (17 females); 21 HC (14 females) were examined using 2-deoxy-2[18F]-fluoro-d-glucose Positron-Emission Tomography (PET) scanning. Read More

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December 2018

Childhood trauma and diagnosis of major depression: Association with memory and executive function.

Psychiatry Res 2018 Dec 30;270:880-886. Epub 2018 Oct 30.

Department of Psychosomatic Medicine, Charité Universitätsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany.

Cognitive function is often impaired in patients with major depressive disorder (MDD). Childhood trauma is a risk factor for developing MDD and is also associated with cognitive impairments in later life. We aimed to investigate the effects of childhood trauma on cognitive function in MDD. Read More

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December 2018
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Assessment of perceived mental health-related stigma: The Stigma-9 Questionnaire (STIG-9).

Psychiatry Res 2018 Dec 10;270:822-830. Epub 2018 Oct 10.

Department of Psychosomatic Medicine and Psychotherapy, University Medical Centre Hamburg-Eppendorf, Germany. Electronic address:

Mental health-related stigma is common and inhibits help-seeking. It triggers fears of devaluation and can add to the burden of a mental disorder. To counter the consequences of mental health-related stigma, its sound assessment is crucial. Read More

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December 2018

Burning mouth syndrome: The challenge of an aging population.

Geriatr Gerontol Int 2018 Dec;18(12):1649-1650

Department of Psychosomatic Dentistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.

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December 2018
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Alternative Splicing Regulator RBM20 and Cardiomyopathy.

Front Mol Biosci 2018 28;5:105. Epub 2018 Nov 28.

Laboratory of Gene Expression, Medical Research Institute, Tokyo Medical and Dental University (TMDU), Tokyo, Japan.

RBM20 is a vertebrate-specific RNA-binding protein with two zinc finger (ZnF) domains, one RNA-recognition motif (RRM)-type RNA-binding domain and an arginine/serine (RS)-rich region. has initially been identified as one of dilated cardiomyopathy (DCM)-linked genes. RBM20 is a regulator of heart-specific alternative splicing and mice lacking the RRM domain are defective in the splicing regulation. Read More

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November 2018

A Comparison of Stress Perception in International and Local First Semester Medical Students Using Psychometric, Psychophysiological, and Humoral Methods.

Int J Environ Res Public Health 2018 Dec 11;15(12). Epub 2018 Dec 11.

Department of General Internal Medicine and Psychosomatics, University Hospital Heidelberg, Ruprecht-Karls-University Heidelberg, 69115 Heidelberg, Germany.

(1) Medical doctors and medical students show increased psychological stress levels. International medical students seem to be particularly vulnerable. (2) We compared different methods of assessing stress levels in international and local first year medical students. Read More

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December 2018

Does Social Exclusion Alter Sensory and Pain Thresholds in Children and Adolescents with Functional Abdominal Pain? - Results from a Preliminary Study.

Pain Med 2018 Dec 13. Epub 2018 Dec 13.

Department of Psychology, Clinical Psychology and Psychotherapy.

Objective: Functional abdominal pain (AP) is a prevalent issue in childhood and adolescence. The contribution of psychosocial factors in the development and maintenance of this health problem is rather unclear, and experimental studies about underlying mechanisms are lacking. This study investigates whether experimentally induced social exclusion decreases sensory and pain thresholds in children suffering from AP. Read More

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December 2018

Quality of Life after Reconstructive Surgery for Intestinal Fistulas.

Acta Medica (Hradec Kralove) 2018 ;61(3):103-107

Department of Gerontology and Metabolism, Teaching Hospital Hradec Králové, Charles University, Faculty of Medicine in Hradec Králové, Hradec Králové, Czech Republic.

Background: This retrospective clinical study would like to objectively denote a quality of life of persons afflicted by an abdominal catastrophe and managed by an extensive surgery can be almost as well conformable as those of healthy people in a similar age group.

Methods: A set of eighteen patients who were successfully surgically treated and cured enjoyed a relatively good convalescence after their surgery and returned to a satisfactory standard of life from the point of view of organ function and psychosomatic state. Statistical analysis of the data collected over a period of 1 to 6 years after this complex therapy using special questionnaire for QOL assessment SF-36 was performed. Read More

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January 2018

Testosterone Insufficiency in Human Immunodeficiency Virus-Infected Women: A Cross-Sectional Study.

Sex Med 2018 Dec 3. Epub 2018 Dec 3.

Department of Sexology & Psychosomatic Obstetrics/Gynecology, Amsterdam University Medical Center, The Netherlands.

Introduction: Now that HIV infection has become a chronic disease, optimizing health status is an important goal of care for HIV-infected patients. Testosterone insufficiency (TI) can compromise health status, but little is known about the prevalence of TI and possible related factors in HIV-infected women.

Aim: To investigate the prevalence of TI among HIV-infected women attending our HIV outpatient clinic, and to study the relationship between TI and sexual function, fatigue, health status, and depression. Read More

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December 2018

[Natural history after discharge from a hospital psychosomatic treatment - Results of a one-year follow-up].

Fortschr Neurol Psychiatr 2018 Dec 12. Epub 2018 Dec 12.

Zentrum für Psychiatrie Südwürttemberg, Abteilung Psychosomatische Medizin Ravensburg.

Background: The effectiveness of the inpatient psychosomatic treatment has been documented in various settings. The question of the sustainability of the improvement achieved as well as the prognostic factors is of interest for public health.

Objective: Primary outcome variables reflect the stability or change in the clinical status of patients one year after the discharge from the inpatient psychosomatic treatment. Read More

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December 2018
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Fatigue in survivors of malignant melanoma and its determinants: a register-based cohort study.

Support Care Cancer 2018 Dec 11. Epub 2018 Dec 11.

Department of Psychosomatic Medicine and Psychotherapy, University Medical Center of the Johannes Gutenberg-University Mainz, Untere Zahlbacher Str. 8, 55131, Mainz, Germany.

Purpose: Fatigue has found increasing attention as a debilitating and lasting condition of cancer patients. However, it has remained unclear to what degree long-term survivors of malignant melanoma suffer from fatigue. Therefore, this study aimed to determine fatigue and its link with quality of life, aftercare behavior, and mental and physical symptoms among melanoma survivors. Read More

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December 2018

Suboptimal health status and psychological symptoms among Chinese college students: a perspective of predictive, preventive and personalised health.

EPMA J 2018 Dec 28;9(4):367-377. Epub 2018 Aug 28.

1School of Public Health, Taishan Medical University, 619 Changcheng Road, Taian, 271016 People's Republic of China.

Background: Suboptimal health status (SHS) is an intermediate health status between health and illness, a syndrome characterised by the perception of health complaints, general weakness and low energy. This study aimed to investigate the prevalence of SHS and the correlation between SHS and psychological symptoms among Chinese college students and to identify the SHS-related risk factors from the perspective of predictive, preventive and personalised medicine (PPPM).

Methods: A cross-sectional study was conducted among 4119 college students who were enrolled from Medical University and Vocational and Technical College in the eastern and western areas of China. Read More

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December 2018
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Dissociative states in borderline personality disorder and their relationships to psychotropic medication.

Neuropsychiatr Dis Treat 2018 23;14:3253-3257. Epub 2018 Nov 23.

Center for Neuropsychiatric Research of Traumatic Stress, Department of Psychiatry and UHSL, 1st Faculty of Medicine, Charles University, Prague, Czech Republic,

Background: According to recent data, dissociation may play an important role in borderline personality disorder (BPD), nevertheless specific influences of psychotropic medication on dissociative symptoms in BPD and their therapeutic indications are largely unknown. The purpose of this study was to assess relationships of dissociative symptoms in BPD patients with levels of psychotropic medication and compare these results with a subgroup of patients with schizophrenia.

Materials And Methods: In this study, we investigated 52 BPD patients and compared the results with a control group of 36 schizophrenia patients. Read More

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November 2018

Placebo response rates and potential modifiers in double-blind randomized controlled trials of second and newer generation antidepressants for major depressive disorder in children and adolescents: a systematic review and meta-regression analysis.

Eur Child Adolesc Psychiatry 2018 Dec 8. Epub 2018 Dec 8.

Department of Child and Adolescent Psychiatry, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.

Children and adolescents with major depressive disorder (MDD) appear to be more responsive to placebo than adults in randomized placebo-controlled trials (RCTs) of second and newer generation antidepressants (SNG-AD). Previous meta-analyses obtained conflicting results regarding modifiers. We aimed to conduct a meta-analytical evaluation of placebo response rates based on both clinician-rating and self-rating scales. Read More

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December 2018

Pharmacokinetic evaluation of linezolid administered intravenously in obese patients with pneumonia.

J Antimicrob Chemother 2018 Dec 7. Epub 2018 Dec 7.

Laboratory of Medical Biochemistry and Clinical Analysis, Faculty of Pharmaceutical Sciences, Ghent University, Ottergemsesteenweg 460, Ghent, Belgium.

Objectives: Altered linezolid pharmacokinetics (PK) in obese individuals has been hypothesized in previous studies. However, specific dosing recommendations for this population are still lacking. The main goal of this study was to evaluate PK/pharmacodynamic (PKPD) target attainment when using a 600 mg intravenous q12h linezolid dose against MRSA in obese patients with pneumonia. Read More

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December 2018

Management of comorbid mental and somatic disorders in stepped care approaches in primary care: a systematic review.

Fam Pract 2018 Dec 7. Epub 2018 Dec 7.

Department of Psychosomatic Medicine and Psychotherapy, University Medical Center Hamburg-Eppendorf, Germany.

Background: Stepped care models comprise a graded treatment intensity and a systematic monitoring. For an effective implementation, stepped care models have to account for the high rates of mental and somatic comorbidity in primary care.

Objectives: The aim of the systematic review was to take stock of whether present stepped care models take comorbidities into consideration. Read More

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December 2018

Medically Unexplained Physical Symptoms in Hospitalized Patients: A 9-Year Retrospective Observational Study.

Front Psychiatry 2018 23;9:626. Epub 2018 Nov 23.

Section of Psychiatry, Department of Medicine and Surgery, University of Insubria, Varese, Italy.

"Medically Unexplained Physical Symptoms" (MUPS) defines a subgroup of patients presenting physical symptoms of unclear origin. The study aims to profile clinical and socio-demographic characteristics of patients with MUPS. This 9-years observational retrospective study assesses all patients admitted between 2008 and 2016 in the divisions of neurology and gastroenterology. Read More

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November 2018

Emotional Reaction to viewing one's own epileptic seizure.

Seizure 2018 Nov 24;64:34-40. Epub 2018 Nov 24.

Epilepsy Center, Freiburg University Medical Center, Germany.

Purpose: If consciousness or memory are impaired during an epileptic seizure, the patient may not experience or know how his/her own seizure looks like. It is disputed, whether being confronted with own seizures may lead to emotional stress or empower patients and decrease negative psychosocial consequences. We assessed patients' reactions to watching a video of their own seizure on measures of anxiety, depression and ten emotions. Read More

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November 2018

The roles of brain-derived neurotrophic factor (BDNF) and glial cell line-derived neurotrophic factor (GDNF) in predicting treatment remission in a Chinese Han population with generalized anxiety disorder.

Psychiatry Res 2018 Aug 30;271:319-324. Epub 2018 Aug 30.

The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325000, PR China. Electronic address:

Neurotrophic factors, particularly brain-derived neurotrophic factor (BDNF) and glial cell line-derived neurotrophic factor (GDNF), are involved in neuroplasticity in the nervous system. To explore the characteristics of BDNF and GDNF and their roles in predicting treatment remission in a Chinese Han population with generalized anxiety disorder (GAD), 85 GAD patients were treated with escitalopram or venlafaxine randomly for 8 weeks. The serum BDNF/GDNF levels were detected, while Hamilton Anxiety Rating Scale (HAMA) scores were measured at baseline and after 8 weeks of treatment. Read More

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Predicting Menstrual Recovery in Adolescents With Anorexia Nervosa Using Body Fat Percent Estimated by Bioimpedance Analysis.

J Adolesc Health 2018 Dec 5. Epub 2018 Dec 5.

Exercise, Nutrition and Lifestyle Clinic, The Edmond and Lily Safra Children's Hospital, Chaim Sheba Medical Center, Ramat-Gan, Israel, affiliated to the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel. Electronic address:

Objective: To identify the threshold of total body fat percentage (TBF%) required for the resumption of menses (ROM) in hospitalized female adolescents with anorexia nervosa (AN) using bioimpedance analysis (BIA).

Methods: All female adolescents hospitalized with AN in our medical center were evaluated in a longitudinal prospective study during the years of 2012-2017. Anthropometric data, body fat measured by BIA, and hormonal determinants were collected periodically, in addition to routine medical and gynecological assessments. Read More

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December 2018

Gender-affirming hormones and surgery in transgender children and adolescents.

Lancet Diabetes Endocrinol 2018 Dec 6. Epub 2018 Dec 6.

Centre and Discipline of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Division of Psychiatry and Clinical Neurosciences and Division of Paediatrics and Child Health, School of Medicine, Faculty of Health and Medical Sciences, University of Western Australia, Perth, WA 6009, Australia; Telethon Kids Institute, University of Western Australia, Perth, WA 6009, Australia; Department of Child and Adolescent Psychiatry, Psychosomatic Medicine and Psychotherapy, Jena University Hospital, Friedrich Schiller University Jena, Germany. Electronic address:

The Endocrine Society Clinical Practice Guidelines on the treatment of gender incongruent people recommend the use of gender-affirming cross-sex hormone (CSH) interventions in transgender children and adolescents who request this treatment, who have undergone psychiatric assessment, and have maintained a persistent transgender identity. The intervention can help to affirm gender identity by inducing masculine or feminine physical characteristics that are congruent with an individual's gender expression, while aiming to improve mental health and quality-of-life outcomes. Some transgender individuals might also wish to access gender-affirming surgeries during adolescence; however, research to inform best clinical practice for surgeons and other medical professionals is scarce. Read More

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December 2018

Predictors of Seeking Psychotherapy in Primary Care Patients with High Somatic Symptom Burden.

Behav Med 2018 Dec 11:1-9. Epub 2018 Dec 11.

a Department of Psychosomatic Medicine and Psychotherapy , University Medical Center Hamburg- Eppendorf , Hamburg , Germany.

Many primary care patients with high somatic symptom burden do not initiate mental health treatment. Using a cross-sectional design, this study aimed to identify predictors of psychotherapy seeking behavior for patients with high somatic symptom burden within the last 12 months. Data from 20 primary care practices were analyzed. Read More

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December 2018

Concurrent Developmental Course of Sleep Problems and Emotional/behavioral Problems in Childhood and Adolescence as Reflected by the Dysregulation Profile.

Sleep 2018 Dec 6. Epub 2018 Dec 6.

Centre and Discipline of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, The University of Western Australia, Perth, WA, Australia.

Objectives: Longitudinal data on the course and relationship of concurrent psychopathology in youth are scarce but are of need for better practical patient care and prevention. This study explores the course of (and relationships over time) between sleep problems and concurrent dimensional difficulties relating to anxiety/depression, attention deficiency and aggressive behaviors in childhood and adolescence. The latter three may jointly form a broad syndrome, the dysregulation profile. Read More

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December 2018
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German National Case Collection for familial pancreatic Cancer (FaPaCa) - acceptance and psychological aspects of a pancreatic cancer screening program.

Hered Cancer Clin Pract 2018 29;16:17. Epub 2018 Nov 29.

1Department of Visceral-, Thoracic- and Vascular Surgery, National Case Collection for Familial Pancreatic Cancer (FaPaCa), Philipps-University Marburg, Baldingerstrasse, 35043 Marburg, Germany.

Background: Pancreatic cancer screening is recommended to individuals at risk (IAR) of familial pancreatic cancer (FPC) families, but little is known about the acceptance of such screening programs. Thus, the acceptance and psychological aspects of a controlled FPC screening program was evaluated.

Methods: IAR of FPC families underwent comprehensive counseling by a geneticist and pancreatologist prior to the proposed screening. Read More

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November 2018
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Norm values and psychometric properties of the brief symptom inventory-18 regarding individuals between the ages of 60 and 95.

BMC Med Res Methodol 2018 Dec 5;18(1):164. Epub 2018 Dec 5.

Department of Medical Psychology and Medical Sociology, University of Leipzig, Leipzig, Germany.

Objective: The SCL-90 and the SCL-90-R are the most applied measures regarding psychological distress. To reduce and prevent an overload to of the individuals, the Brief Symptom Inventory with 18 items (BSI-18) was developed based on the SCL-90. Since psychological disorders more frequently occur at an older age, there is a growing need for efficient instruments to measure distress in the elderly. Read More

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December 2018
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Predicting presenteeism via effort-reward imbalance and dispositional optimism: Is it the interaction that matters? Results from the saxony longitudinal study.

Work 2018 Nov 26. Epub 2018 Nov 26.

Department of Psychosomatic Medicine and Psychotherapy, University Medical Center of the Johannes Gutenberg-University, Mainz, Germany.

Background: The importance of experienced work stress and individual traits as well as their interplay is analyzed with regard to dysfunctional coping behavior in case of sickness.

Objective: The aim of this study was to examine the predictive capability of effort-reward imbalance (ERI) including overcommitment, meaning the intrinsic propensity in terms of excessive work-related expenditure (OC), in consideration of dispositional optimism/pessimism on presenteeism.

Methods: A total of 353 men and women aged 38 from the 25th panel wave of The Saxony Longitudinal Study in 2011 were included in the analysis. Read More

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November 2018
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Reducing intrusive memories of trauma using a visuospatial interference intervention with inpatients with posttraumatic stress disorder (PTSD).

J Consult Clin Psychol 2018 Dec;86(12):1076-1090

Department of Psychosomatic Medicine and Psychotherapy.

Objective: The core clinical feature of posttraumatic stress disorder (PTSD) is recurrent intrusive memories of trauma. This study aimed to test a novel and simple intervention, inspired by the concepts of concurrent task interference and memory reconsolidation, to reduce the occurrence of intrusive memories among inpatients with complex PTSD.

Method: In this open-label single case series 20 patients with longstanding complex PTSD in inpatient treatment monitored the occurrence of intrusive trauma memories (intrusions) over the course of their admission (5 to 10 weeks). Read More

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December 2018
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Clinical significance of sensory hypersensitivities in migraine patients: does allodynia have a priority on it?

Neurol Sci 2018 Dec 1. Epub 2018 Dec 1.

Department of Neurology, School of Medicine, Kyungpook National University, 680 Gukchaebosang-ro, Jung-gu, Daegu, 41944, Republic of Korea.

Objectives: This study investigated to identify the clinical significance of allodynia compared with other sensory hypersensitivities (SH) in migraine patients.

Methods: New patients with migraine were recruited from a headache clinic, and we collected data regarding their clinical characteristics and identified SH including photophobia, phonophobia, osmophobia, and allodynia. The patients completed the 12-item Allodynia Symptom Checklist, Migraine Disability Assessment Scale (MIDAS), Headache Impact Test-6 (HIT-6), Patient Health Questionnaire-9 (PHQ-9), Generalized Anxiety Disorder-7 (GAD-7), Insomnia Severity Index (ISI), Fatigue Severity Scale (FSS), and Migraine-Specific Quality of Life Questionnaire Version 2. Read More

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December 2018
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Direct assessment of adherence and drug interactions in patients with hypertensive crisis-A cross-sectional study in the Emergency Department.

J Clin Hypertens (Greenwich) 2018 Dec 5. Epub 2018 Dec 5.

Department of Nephrology and Rheumatology, University Medical Center Göttingen, Göttingen, Germany.

Though drug adherence is supposed to be low in hypertensive crisis (HTN-C), there are no data available from direct adherence assessments. The aim of the present study was to evaluate adherence to prescribed antihypertensives and potential interactions of concomitant drugs and foods with prescribed antihypertensives in patients with HTN-C by a direct evaluation via biochemical urine analysis. In the present cross-sectional study, 100 patients with HTN-C, admitted to the emergency department (ED), were included. Read More

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December 2018
2 Reads

Public Beliefs About Somatic Symptom Disorders.

Front Psychiatry 2018 20;9:616. Epub 2018 Nov 20.

Institute of Medical Sociology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

Despite satisfactory effectiveness of treatment for somatic symptom disorders (SSD), treatment rates are low and treatment is usually initiated many years after first symptoms. In order to understand whether a lack of public mental health literacy might contribute to these poor treatment rates, we aimed to focus on two research questions: (1) What does the German public know and think about SSD? (2) Are knowledge and beliefs associated with socio-demographic factors and experiences with the disorder? Two vignettes with symptoms of a SSD were used in a national telephone survey in Germany ( = 1,004). Vignettes differed regarding main type of symptom (pain vs. Read More

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November 2018
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Efficacy of psychotherapies and pharmacotherapies for Bulimia nervosa.

Psychol Med 2018 Dec 5:1-13. Epub 2018 Dec 5.

Department of Clinical Psychology and Psychotherapy,University of Freiburg,Engelbergerstrasse 41, 79085 Freiburg,Germany.

Background: Bulimia nervosa (BN), a mental disorder that causes significant impairment, can be treated with psychological, pharmacological, nutrition-based and self-help interventions. We conducted a pre-registered meta-analysis of randomized-controlled trials (RCTs) to assess the efficacy of these interventions in up to 19 different interventions.

Methods: Database search terms were combined for BN and RCTs from database inception to March 2017. Read More

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December 2018
5 Reads

Nesfatin-1 Injected Intracerebroventricularly Increases Anxiety, Depression-Like Behavior, and Anhedonia in Normal Weight Rats.

Nutrients 2018 Dec 3;10(12). Epub 2018 Dec 3.

Charité Center for Internal Medicine and Dermatology, Department for Psychosomatic Medicine, Charité-Universitätsmedizin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, 12203 Berlin, Germany.

Nesfatin-1 is a well-established anorexigenic peptide. Recent studies indicated an association between nesfatin-1 and anxiety/depression-like behavior. However, it is unclear whether this effect is retained in obesity. Read More

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December 2018
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A School-Based Program to Promote Well-Being in Preadolescents: Results From a Cluster Quasi-Experimental Controlled Study.

J Prim Prev 2018 Dec 3. Epub 2018 Dec 3.

Department of Translational Medicine, Università del Piemonte Orientale, Via Solaroli 17, Novara, Italy.

Diario della Salute [My Health Diary] is a school-based program designed to enhance the subjective well-being and health of 12- to 13-year-old students. We hypothesized that providing students with the social and emotional skills to fulfill their potential and deal with common developmental tasks of adolescence (e.g. Read More

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December 2018
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[Higher prevalence of depressive and anxiety symptoms in early arthritis patients in comparison to the normal population].

Z Rheumatol 2018 Dec 3. Epub 2018 Dec 3.

Klinik für Rheumatologie und klinische Immunologie, Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117, Berlin, Deutschland.

Background: Many studies and registry data confirm that depression, often associated with anxiety disorders is very often found in patients with rheumatoid arthritis (RA). To what extent these psychiatric disorders are already relevant at a very early stage of the disease, has currently not been adequately investigated.

Methods: In this study 176 patients with early joint symptoms (<1 year) were surveyed in an early arthritis consultation (EAC). Read More

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December 2018
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Psychosocial stress impairs health behavior in patients with mental disorders.

BMC Psychiatry 2018 Dec 4;18(1):375. Epub 2018 Dec 4.

Department of Psychosomatic Medicine and Psychotherapy, University Medical Center of the Johannes Gutenberg University Mainz, Untere Zahlbacher Str. 8, 55131, Mainz, Germany.

Background: It has been shown, that in the general population psychosocial stress affects health behaviors. However similar studies of high risk populations are sparse. Therefore, the aim of this cross-sectional study is to analyze the association between common psychosocial stressors and health behavior in a sample of patients with mental disorders. Read More

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December 2018
4 Reads

Effects of exercise interventions for specific cognitive domains in old adults with mild cognitive impairment: A protocol of subgroup meta-analysis of randomized controlled trials.

Medicine (Baltimore) 2018 Nov;97(48):e13244

School of Nursing, Medical College of Huzhou University.

Background: Mild cognitive impairment (MCI) is the clinical prognosis that leads to dementia. Early intervention of MCI is critical to protect against dementia. Exercise intervention has gained popularity for the management of MCI. Read More

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November 2018

Olfactory change detection.

Biol Psychol 2018 Nov 27;140:75-80. Epub 2018 Nov 27.

Department of Psychotherapy and Psychosomatic Medicine, Medizinische Fakultät Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany. Electronic address:

The human olfactory system is characterized by poor temporal and spatial resolution. When determining changes in the environment, humans rather rely on visual than on olfactory information. Against this background, we developed a test in order to investigate the human capacity to detect changes in the olfactory environment and to determine potential modulators of olfactory change detection. Read More

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November 2018

A Systematic Review of Interventions for Health Anxiety Presentations Across Diverse Chronic Illnesses.

Int J Behav Med 2018 Nov 29. Epub 2018 Nov 29.

School of Psychology, University of Ottawa, 136 Jean Jacques Lussier PVT, Ottawa, Ontario, K1N 6N5, Canada.

Purpose: Health anxiety (HA) is associated with reduced quality of life among individuals with chronic illnesses. However, little is known about effective interventions for reducing HA in this context. This study aimed to comprehensively review the literature on interventions for the treatment of HA in chronic illness. Read More

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November 2018

Effects of social exclusion and physical pain in chronic opioid maintenance treatment: fMRI correlates.

Eur Neuropsychopharmacol 2018 Nov 27. Epub 2018 Nov 27.

Department of Addictive Behavior and Addiction Medicine, Central Institute of Mental Health, University of Heidelberg, Medical Faculty Mannheim, Square J5, D-68159 Mannheim, Germany.

Opioids interact with systems processing pain and social stimuli. Both systems are crucial for responding to strains of everyday life and both are linked to relapse risk in opioid-dependent patients. The investigation of those systems seems essential to better understand opioid addiction as a whole. Read More

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November 2018

Internal and external signal processing in patients with panic disorder: An event-related potential (ERP) study.

PLoS One 2018 29;13(11):e0208257. Epub 2018 Nov 29.

International Psychoanalytic University Berlin, Berlin, Germany.

Self-absorption describes a pathological tendency towards the internal mental world (internalization) that often conflicts with the accurate monitoring of the external world. In performance monitoring, an augmented electrophysiological response evoked by internal signals in patients with anxiety or depressive disorder seems to reflect this tendency. Specifically, the error-related negativity (Ne/ERN), an index of error processing based on internal signals, is larger in patients compared to controls. Read More

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November 2018
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Maternal psychopathology and mental health treatment delay in adolescents from a national cohort.

Health Serv Res 2018 Nov 28. Epub 2018 Nov 28.

Division of Clinical Psychology and Psychiatry, Department of Psychology, University of Basel, Basel, Switzerland.

Objective: To investigate whether maternal psychopathology predicts mental health service use and treatment delay in offspring with mental disorders.

Data Sources: Weighted data collected between 2001 and 2004 from NCS-A participants (age: 13-18 years; N = 2939) meeting DSM-IV criteria for any lifetime mental disorder, assessed with WHO CIDI, and from their biological mothers.

Study Design: National representative cohort. Read More

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November 2018
2 Reads

The role of self-esteem in the treatment of patients with anorexia nervosa - A systematic review and meta-analysis.

Int J Eat Disord 2018 Nov 28. Epub 2018 Nov 28.

Department of Psychosomatic Medicine and Psychotherapy, University Medical Centre, Hamburg-Eppendorf & Schön Clinic Hamburg Eilbek, Hamburg, Germany.

Objective: We aimed to provide a comprehensive overview of the role of self-esteem in the treatment of patients with anorexia nervosa (AN). Specifically, our objectives were to investigate the differences in self-esteem between individuals with AN and healthy controls, or individuals with other eating disorders, and to examine self-esteem as an outcome, predictor, moderator, and mediator in AN treatment.

Method: The databases PsycINFO, PSYNDEXplus, Ovid MEDLINE®, and ProQuest were searched for studies published from 1990 to 2018. Read More

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November 2018
1 Read

Medical Cannabis for Older Patients.

Drugs Aging 2018 Nov 29. Epub 2018 Nov 29.

Alan Edwards Pain Management Unit, McGill University Health Centre, Montreal, QC, Canada.

Interest in the medicinal use of cannabis and cannabinoids is mounting worldwide. Fueled by enthusiastic media coverage, patients perceive cannabinoids as a natural remedy for many symptoms. Cannabinoid use is of particular interest for older individuals who may experience symptoms such as chronic pain, sleep disturbance, cancer-related symptoms and mood disorders, all of which are often poorly controlled by current drug treatments that may also incur medication-induced side effects. Read More

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November 2018
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Neurologists' Assessment of Mental Comorbidity in Patients With Vertigo and Dizziness in Routine Clinical Care-Comparison With a Structured Clinical Interview.

Front Neurol 2018 13;9:957. Epub 2018 Nov 13.

Department of Psychosomatic Medicine and Psychotherapy, University Medical Center Freiburg, Freiburg, Germany.

Mental health comorbidities are frequent in patients with vertigo and dizziness. The current study was conducted in a specialized interdisciplinary university center for vertigo and dizziness. Clinical routines consist of a structured work-up in which neuro-otological and neurological tests are performed to first detect possible organic vestibular deficits. Read More

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November 2018
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Chronic traumatic encephalopathy: neuroimaging biomarkers.

Handb Clin Neurol 2018 ;158:309-322

Psychiatric Neuroimaging Laboratory, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States; Department of Child and Adolescent Psychiatry, Psychosomatic, and Psychotherapy, Ludwig-Maximilians-Universität, Munich, Germany. Electronic address:

Chronic traumatic encephalopathy (CTE) is a neurodegenerative disorder associated with repetitive head impact exposure, such as that resulting from sports-related concussive and subconcussive brain trauma. Currently, the only way to diagnose CTE is by using neuropathologic markers obtained postmortem. To diagnose CTE earlier, so that possible treatment interventions may be employed, there is a need to develop noninvasive in vivo biomarkers of CTE. Read More

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January 2018
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