12,302 results match your criteria Psychiatry research[Journal]


Plasma levels of leptin and adiponectin and depressive symptoms in young adults.

Psychiatry Res 2018 Dec 3;272:1-7. Epub 2018 Dec 3.

Department of Neuroscience, Psychiatry, Uppsala University, Akademiska sjukhuset, 751 85, Uppsala, Sweden. Electronic address:

Circulating levels of adipokines are known to be associated with depression. This study aimed to investigate a possible association between leptin, adiponectin and dimensional measures of depressive symptoms in young adults with and without psychiatric illness. Total plasma adiponectin and leptin levels were measured in 194 young adults seeking psychiatric ambulatory care and 57 healthy controls. Read More

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http://dx.doi.org/10.1016/j.psychres.2018.11.075DOI Listing
December 2018

Overconfidence in false autobiographical memories in patients with schizophrenia.

Psychiatry Res 2018 Dec 10. Epub 2018 Dec 10.

Shanghai Key Laboratory of Brain Functional Genomics, Shanghai Key Laboratory of Magnetic Resonance, School of Psychology and Cognitive Science, East China Normal University, NYU-ECNU Institute of Brain and Cognitive Science at NYU Shanghai, Shanghai 200062, China. Electronic address:

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http://dx.doi.org/10.1016/j.psychres.2018.12.063DOI Listing
December 2018

Convergent microstructural brain changes across genetic models of autism spectrum disorder-A pilot study.

Psychiatry Res Neuroimaging 2018 Dec 8;283:83-91. Epub 2018 Dec 8.

Department of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53705, USA; Department of Psychiatry, University of Wisconsin, School of Medicine and Public Health, Madison, WI 53705, USA; Department of Biomedical Engineering, University of Wisconsin-Madison, Madison, WI, 53706 USA; Neuroscience Training Program, University of Wisconsin-Madison, Madison, WI, 53705 USA. Electronic address:

Autism spectrum disorder (ASD) is a complex and genetically heterogeneous neuropsychiatric disease affecting as many as 1 in 68 children. Large scale genetic sequencing of individuals along the autism spectrum has uncovered several genetic risk factors for ASD; however, understanding how, and to what extent, individual genes contribute to the overall disease phenotype remains unclear. Neuroimaging studies of ASD have revealed a wide spectrum of structural and functional perturbations that are thought to reflect, in part, the complex genetic heterogeneity underpinning ASD. Read More

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http://dx.doi.org/10.1016/j.pscychresns.2018.12.007DOI Listing
December 2018

Relationship between depressive symptom severity and amygdala volume in a large community-based sample.

Psychiatry Res Neuroimaging 2018 Dec 6;283:77-82. Epub 2018 Dec 6.

Department of Psychiatry, The University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd. MC 8849, Dallas, TX, USA. Electronic address:

Amygdala is an affective processing center that regulates and assigns valence to different emotions and has been implicated in the pathophysiology of mood disorders. This population-based study employed a community sample of 1747 adults to examine relationships between amygdala volume and depressive symptom severity. Neuroimaging data from participants in the Dallas Heart Study were used. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S09254927183006
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http://dx.doi.org/10.1016/j.pscychresns.2018.12.005DOI Listing
December 2018
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FMRI correlates of olfactory processing in typically-developing school-aged children.

Psychiatry Res Neuroimaging 2018 Dec 2;283:67-76. Epub 2018 Dec 2.

Department of Radiology, University of Washington, Seattle, WA, United States; Center on Human Development and Disability, University of Washington, Seattle, WA, United States; Department of Biomedical Engineering, University of Washington, Seattle, WA, United States.

Human olfactory processing is understudied relative to other sensory modalities, despite its links to neurodevelopmental and neurodegenerative disorders. To address this limitation, we developed a fast, robust fMRI odor paradigm that is appropriate for all ages and levels of cognitive functioning. To test this approach, thirty-four typically developing children aged 7-12 underwent fMRI during brief, repeated exposure to phenylethyl alcohol, a flower-scented odor. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S09254927183013
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http://dx.doi.org/10.1016/j.pscychresns.2018.11.011DOI Listing
December 2018
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Does obtaining CYP2D6 and CYP2C19 pharmacogenetic testing predict antidepressant response or adverse drug reactions?

Psychiatry Res 2018 Dec 8;271:604-613. Epub 2018 Dec 8.

Harvard South Shore Psychiatry Residency Training Program, Brockton, MA, USA; Department of Psychiatry, Veterans Affairs Boston Healthcare System, Boston, MA, USA; Department of Psychiatry, Harvard Medical School, Boston, MA, USA.

Treatment non-response and adverse reactions are common in patients receiving antidepressants. Personalizing psychiatric treatment based on pharmacogenetic testing has been proposed to help clinicians guide antidepressant selection and dosing. This systematic literature review assesses the two most robustly studied drug-metabolizing enzymes, CYP2D6 and CYP2C19, and examines whether obtaining CYP2D6 and CYP2C19 testing can be used to predict antidepressant response or adverse drug reactions in order to improve clinical outcomes. Read More

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http://dx.doi.org/10.1016/j.psychres.2018.12.053DOI Listing
December 2018

No association between common genetic variation in FOXP2 and language impairment in schizophrenia.

Psychiatry Res 2018 Dec 6;271:590-597. Epub 2018 Dec 6.

Division of Psychiatry, Centre for Clinical Research in Neuropsychiatry, Faculty of Health and Medical Sciences, The University of Western Australia, Medical Research Foundation Building, Perth WA 6000, Australia; Perth Voices Clinic, South Street, Murdoch, WA 6150, Australia. Electronic address:

The FOXP2 gene is hypothesised to be involved in schizophrenia by affecting speech and language development. Associations between common single nucleotide polymorphisms (SNPs) in FOXP2 and language have been inconsistent. We tested five previously associated SNPs for association with language in the Western Australian Family Study of Schizophrenia (n = 709, including n = 333 with schizophrenia/spectrum disorder) and found no significant associations. Read More

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http://dx.doi.org/10.1016/j.psychres.2018.12.016DOI Listing
December 2018

The roles of cognitive avoidance, rumination and negative affect in the association between abusive supervision in the workplace and non-clinical paranoia in a sample of workers working in France.

Psychiatry Res 2018 Dec 6;271:581-589. Epub 2018 Dec 6.

Univ Paul Valéry Montpellier 3, Univ. Montpellier, EPSYLON EA 4556, F34000, Montpellier, France; CHU Montpellier, Epsylon Laboratory, University Department of Adult Psychiatry, Rue du Pr. Henri Serre, 34000, Montpellier, EA 4556, France.

This study examined the relationship between abusive supervision and non-clinical paranoia and explored which cognitive mechanisms are mediating this association (i.e. rumination, cognitive avoidance and negative affect). Read More

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http://dx.doi.org/10.1016/j.psychres.2018.11.065DOI Listing
December 2018

Cognitive mechanisms of alexithymia in schizophrenia: Investigating the role of basic neurocognitive functioning and cognitive biases.

Psychiatry Res 2018 Dec 4;271:573-580. Epub 2018 Dec 4.

II Department of Psychiatry, Medical University of Warsaw, Kondratowicza 8, 03-242 Warsaw, Poland.

Alexithymia is an important but poorly understood emotional deficit in schizophrenia. We aimed at investigating the role of basic cognitive functions, cognitive biases, and symptom severity in alexithymia among patients with schizophrenia. Sixty patients (31 females) with schizophrenia were assessed with standardized clinical interviews for symptom severity. Read More

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http://dx.doi.org/10.1016/j.psychres.2018.12.023DOI Listing
December 2018

Post-migration treatment targets associated with reductions in depression and PTSD among survivors of torture seeking asylum in the USA.

Psychiatry Res 2018 Dec 8;271:565-572. Epub 2018 Dec 8.

Bellevue/NYU Program for Survivors of Torture, Bellevue Hospital Center, 462 First Avenue, CD732, New York, NY 10016, USA.

Mental health research among asylum seekers and refugees has largely focused on effects of pre-migration trauma on post-migration wellbeing. While emerging literature highlights the importance of post-migration factors, we do not yet understand how addressing these factors may influence change in psychological distress. This study uses archival clinical data to identify post-migration correlates of reductions in distress among torture survivors, after accounting for pre-migration trauma. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01651781183072
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http://dx.doi.org/10.1016/j.psychres.2018.12.047DOI Listing
December 2018
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Public stigma of obsessive compulsive disorder and schizophrenic disorder: Is there really any difference?

Psychiatry Res 2018 Dec 10;271:559-564. Epub 2018 Dec 10.

Department of Psychology, Faculty of Arts, Dokuz Eylül University, Buca, İzmir, Turkey.

A substantial delay for help-seeking is a serious problem for people with obsessive-compulsive disorder (OCD), a heterogeneous and debilitating mental health condition. Stigma is a major barrier to treatment seeking and further cause social and occupational impairment. Lack of comprehensive research led us to examine the public's stigmatizing attitudes towards checking, contamination, sexuality, aggression, and religion-related OCD symptoms, compared to schizophrenia. Read More

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http://dx.doi.org/10.1016/j.psychres.2018.12.065DOI Listing
December 2018
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Genetic variability in the serotoninergic system and age of onset in anorexia nervosa and obsessive-compulsive disorder.

Psychiatry Res 2018 Dec 6;271:554-558. Epub 2018 Dec 6.

Department of Child and Adolescent Psychiatry and Psychology, Institute of Neurosciences, Hospital Clinic de Barcelona, C/ Villarroel 170, E-08036 Barcelona, Spain; Department of Medicine, University of Barcelona, Barcelona, Spain; The August Pi i Sunyer Biomedical Research Institute (IDIBAPS), Barcelona, Spain; Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Carlos III Health Institute, Spain. Electronic address:

The age of onset of some psychiatric disorders may have etiopathogenic and clinical effects and may influence outcome. Following on from previous work by our group where we showed that early onset anorexia nervosa (AN) and obsessive-compulsive disorder (OCD) shared a common genetic background, the aim of the present study is to assess genetic pleiotropy related to the serotonergic system (SLC6A4, 5HTR2A, 5HTR2C, TPH2, SLC18A1), in a common phenotype such as very-early age of onset. One hundred and sixteen adolescents diagnosed with AN and 74 adolescents diagnosed with OCD participated in the present study. Read More

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http://dx.doi.org/10.1016/j.psychres.2018.12.019DOI Listing
December 2018

Meaning in life buffers the association between clinical anxiety and global maladjustment in participants with common mental disorders on sick leave.

Psychiatry Res 2018 Dec 6;271:548-553. Epub 2018 Dec 6.

Escuela de doctorado. Universidad Católica de Valencia, San Vicente Mártir, España; Catedra UMIVALE Innovación e investigación en patologías del trabajo, Valencia, España.

An important goal of mental health specialists is to improve the quality of life and the adaptation of people with common mental disorders on sick leave. Meaning in life is a protective factor for people adjusting to distress and negative events. This study explores the buffering role of meaning in life in the relationship between clinical anxiety or negative affect and maladjustment in participants with common mental disorders on sick leave. Read More

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http://dx.doi.org/10.1016/j.psychres.2018.12.027DOI Listing
December 2018

Psychobiological response to an anger induction task in schizophrenia: The key role of anxiety.

Psychiatry Res 2018 Dec 7;271:541-547. Epub 2018 Dec 7.

Unitat de Psiquiatria i Psicologia Mèdica, Facultat de Medicina, Universitat de València, Avda. Blasco Ibáñez 15, València E. 46010, Spain; Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM); Hospital Clínico Universitario de Valencia . Instituto de Investigación Sanitaria (INCLIVA).

In this study an anger induction laboratory task was applied to men with schizophrenia, and resulted in significant changes in different psychophysiological parameters that were measured in a pre-post design. We observed a significantly greater self-reported anger mood and negative affection, lower self-reported positive affection, an increase in cardiovascular reactivity (with blood pressure in deeper affection compared to controls), higher salivary testosterone levels, lower salivary cortisol levels, and an increase in right ear items reported in dichotic listening. Furthermore, clinical risk factors related to anger in our patients were analyzed by Stepwise Regression analyses. Read More

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http://dx.doi.org/10.1016/j.psychres.2018.12.044DOI Listing
December 2018

Fluorodeoxyglucose positron emission tomography studies of the schizophrenia spectrum: The legacy of Monte S. Buchsbaum, M.D.

Psychiatry Res 2018 Dec 7;271:535-540. Epub 2018 Dec 7.

Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, United States; Mental Illness Research, Education, and Clinical Center (VISN 2), James J. Peters VA Medical Center, 130 West Kingsbridge Road, Room 6A-44, Bronx, NY, United States.

This is a selective review of the work of Buchsbaum and colleagues. It revisits and pays tribute to four decades of publications employing positron emission tomography (PET) with fluorodeoxyglucose (FDG) to examine the neurobiology of schizophrenia-spectrum disorders (including schizotypal personality disorder (SPD) and schizophrenia). Beginning with a landmark FDG-PET study in 1982 reporting hypofrontality in unmedicated schizophrenia patients, Buchsbaum and colleagues published high-impact work on regional glucose metabolic rate (GMR) abnormalities in the spectrum. Read More

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http://dx.doi.org/10.1016/j.psychres.2018.12.030DOI Listing
December 2018
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PHQ-9: One factor or two?

Psychiatry Res 2018 Dec 7;271:532-534. Epub 2018 Dec 7.

Department of Psychology, University of Durham, Durham, United Kingdom; Clinical Psychology, Teesside University, Middlesbrough, United Kingdom. Electronic address:

The PHQ-9 has been found to be reliable and valid, but with both a single and two-factor structure suggested in the literature. This measure has not yet been subject to psychometric investigation using Mokken scale analysis. Confirmatory Factor Analysis (CFA) and Mokken analysis were performed on retrospective data from an NHS Trust. Read More

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http://dx.doi.org/10.1016/j.psychres.2018.12.048DOI Listing
December 2018

How does self-esteem affect mobile phone addiction? The mediating role of social anxiety and interpersonal sensitivity.

Psychiatry Res 2018 Dec 6;271:526-531. Epub 2018 Dec 6.

College of Humanities, Hubei University of Chinese Medicine, China.

Low self-esteem is an important factor influencing mobile phone addiction, which has been well documented. However, little research focused on the mechanism underlying the association between self-esteem and mobile phone addiction. We hypothesized that social anxiety and interpersonal sensitivity may mediate the relationship between self-esteem and mobile phone addiction. Read More

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http://dx.doi.org/10.1016/j.psychres.2018.12.040DOI Listing
December 2018

Pet robot intervention for people with dementia: A systematic review and meta-analysis of randomized controlled trials.

Psychiatry Res 2018 Dec 6;271:516-525. Epub 2018 Dec 6.

School of Nursing, Jilin University, Changchun, China; Department of Pharmacology, college of Basic Medical sciences, Jilin University, Changchun, China. Electronic address:

This study aims to systematically evaluate the efficacy of Pet robot intervention (PRI) for people with dementia. Two waves of electronic searches of the PubMed, EMBASE, Web of Science, Cochrane library, IEEE Digital Library and PsycINFO databases were conducted. In total, eight articles from six randomized controlled trials (RCTs) met the eligibility criteria and were included in this systematic review. Read More

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http://dx.doi.org/10.1016/j.psychres.2018.12.032DOI Listing
December 2018
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Short abstinence from online social networking sites reduces perceived stress, especially in excessive users.

Psychiatry Res 2018 Dec 9;270:947-953. Epub 2018 Nov 9.

Michigan State University, 293 Farm Lane, East Lansing, MI 48824, United States.

Online social networking sites (SNSs), such as Facebook, provide frequent and copious social reinforcers (e.g., "likes") delivered at variable time intervals. Read More

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http://dx.doi.org/10.1016/j.psychres.2018.11.017DOI Listing
December 2018

Pathological alterations of chondroitin sulfate moiety in postmortem hippocampus of patients with schizophrenia.

Psychiatry Res 2018 Dec 30;270:940-946. Epub 2018 Oct 30.

Department of Molecular Neurobiology, Brain Research Institute, Niigata University, 1-757, Asahimachi-dori, Chuo-ku Niigata, Niigata 951-8585, Japan. Electronic address:

Perineuronal nets comprise chondroitin sulfate moieties and their core proteins, and their neuropathological alterations have been implicated in schizophrenia. To explore the molecular mechanism of the perineuronal net impairments in schizophrenia, we measured the immunoreactivity of chondroitin sulfate moieties, major components of perineuronal nets, in three brain regions (postmortem dorsolateral prefrontal cortex, caudate nucleus, and hippocampus) of schizophrenia patients and control subjects. Immunoblotting for chondroitin 4-sulfate and chondroitin 6-sulfate moieties revealed a significant increase in intensity of a 180 kD band of chondroitin 4-sulfate immunoreactivity in the hippocampus of patients, although we detected no significant alteration in their immunoreactivities with any other molecular sizes or in other brain regions. Read More

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http://dx.doi.org/10.1016/j.psychres.2018.10.062DOI Listing
December 2018
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Is the perception of illusions abnormal in schizophrenia?

Psychiatry Res 2018 Dec 30;270:929-939. Epub 2018 Oct 30.

Laboratory of Psychophysics, Brain Mind Institute, École Polytechnique Fédérale de Lausanne (EPFL), Switzerland.

There seems to be no common factor for visual perception, i.e., performance in visual tasks correlates only weakly with each other. Read More

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http://dx.doi.org/10.1016/j.psychres.2018.10.063DOI Listing
December 2018

The characterization of social anhedonia and its correlates in schizophrenia and schizoaffective patients.

Psychiatry Res 2018 Dec 4;270:922-928. Epub 2018 Nov 4.

Department of Psychology, University of Wisconsin-Madison, 1202 W. Johnson Street, Madison, WI 53706, United States. Electronic address:

Although social hedonic capacity is often assessed in clinical settings, its operational definitions have not been evaluated for concurrent validity. One hundred and twenty-five patients with schizophrenia and schizoaffective disorder were classified according to their self-reported social hedonic functioning into three groups on the basis of their total scores on the Anticipatory and Consummatory Interpersonal Pleasure Scale (ACIPS). Participants were assessed before discharge using questionnaires and psychiatric rating scales. Read More

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http://dx.doi.org/10.1016/j.psychres.2018.11.003DOI Listing
December 2018

Psychological and electrophysiological indices of inattention in hoarding.

Psychiatry Res 2018 Dec 5;270:915-921. Epub 2018 Nov 5.

School of Psychology, University of New South Wales, Sydney, New South Wales 2052, Australia.

Individuals with elevated hoarding symptoms report elevated symptoms of ADHD and these symptoms are related to impaired daily functioning. Neuropsychological studies have found specific deficits in attention, and a recent review of attentional data from numerous hoarding studies concluded that inattention likely represents an etiological factor in hoarding, rather than a comorbidity. Our study aimed to examine which symptoms of ADHD, inattention or hyperactivity, are related to hoarding symptom severity, and whether individuals with hoarding symptoms display a neurophysiological marker of poor attention (Theta/Beta Ratio; THBR) that might explain these associations. Read More

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http://dx.doi.org/10.1016/j.psychres.2018.11.009DOI Listing
December 2018

Associations of specific and multiple types of childhood abuse and neglect with personality pathology among adolescents referred for mental health services.

Psychiatry Res 2018 Dec 8;270:906-914. Epub 2018 Nov 8.

Department of Clinical, Neuro and Developmental Psychology, Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, The Netherlands.

The present study investigated the unique association between five types of childhood abuse and neglect and 18 lower-order dimensions of personality pathology, and using latent classes analysis (LCA) explored patterns of childhood abuse or neglect experiences. Further differences across latent classes on personality pathology traits, personality disorder symptom count and a diagnosis of personality disorder were examined. Participants were 178 adolescents and young adults (12-22 years; M = 16. Read More

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http://dx.doi.org/10.1016/j.psychres.2018.11.016DOI Listing
December 2018

Burnout is more strongly linked to neuroticism than to work-contextualized factors.

Authors:
Renzo Bianchi

Psychiatry Res 2018 Dec 8;270:901-905. Epub 2018 Nov 8.

Institute of Work and Organizational Psychology, University of Neuchâtel, Neuchâtel, NE, Switzerland. Electronic address:

Burnout has been regarded as a negative affective state resulting from unresolvable job stress. A widespread idea among burnout researchers is that burnout is primarily linked to work-contextualized factors, and only limitedly dependent on general dispositional factors. The validity of this view, however, remains unclear. Read More

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http://dx.doi.org/10.1016/j.psychres.2018.11.015DOI Listing
December 2018

The association between schizotypal traits and social functioning in adolescents from the general population.

Psychiatry Res 2018 Dec 5;270:895-900. Epub 2018 Nov 5.

Bristol Medical School, Population Health Sciences, University of Bristol, Bristol, UK.

Difficulties in social functioning have been linked to schizotypy, which may reflect vulnerability to psychotic disorders. We investigated these links in early adolescence, a developmental stage when many mental illnesses first emerge. Using the Strength and Difficulties Questionnaire and The Community Assessment of Psychic Experiences, we examined the association of peer-relationship problems and prosocial behavior with positive and negative schizotypy in a sample of 149 school children (70 girls, 79 boys) between 12 and 15 years old. Read More

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http://dx.doi.org/10.1016/j.psychres.2018.11.007DOI Listing
December 2018

Social cognition and interaction training for major depression: A preliminary study.

Psychiatry Res 2018 Dec 5;270:890-894. Epub 2018 Nov 5.

Department of Psychiatry, The Seventh Hospital of Hangzhou, 305 Tianmushan Road, Hangzhou, 310013, Zhejiang Province, China. Electronic address:

The present work investigated the efficacy of social cognition and interaction training (SCIT) for patients with major depression. Thirty first-episode patients with major depression who received the SCIT plus the treatment-as-usual (i.e. Read More

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http://dx.doi.org/10.1016/j.psychres.2018.11.008DOI Listing
December 2018
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Childhood trauma and diagnosis of major depression: Association with memory and executive function.

Psychiatry Res 2018 Dec 30;270:880-886. Epub 2018 Oct 30.

Department of Psychosomatic Medicine, Charité Universitätsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany.

Cognitive function is often impaired in patients with major depressive disorder (MDD). Childhood trauma is a risk factor for developing MDD and is also associated with cognitive impairments in later life. We aimed to investigate the effects of childhood trauma on cognitive function in MDD. Read More

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http://dx.doi.org/10.1016/j.psychres.2018.10.071DOI Listing
December 2018
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The component structure of the scales for the assessment of positive and negative symptoms in first-episode psychosis and its dependence on variations in analytic methods.

Psychiatry Res 2018 Dec 30;270:869-879. Epub 2018 Oct 30.

Clinical Psychology Unit, Department of Psychology, University of Sheffield, UK. Electronic address:

A secondary analysis was undertaken on Scales for the Assessment of Positive and Negative Symptoms (SAPS/SANS) data from 345 first-episode psychosis (FEP) patients gathered in the West London FEP study. The purpose of this study was to determine: (i) the component structure of these measures in FEP (primary analyses), and (ii) the dependence of any findings in these primary analyses on variations in analytic methods. Symptom ratings were exposed to data reduction methods and the effects of the following manipulations ascertained: (i) level of analysis (individual symptom vs. Read More

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http://dx.doi.org/10.1016/j.psychres.2018.10.046DOI Listing
December 2018

Validity of a two-item screen for early psychosis.

Psychiatry Res 2018 Dec 3;270:861-868. Epub 2018 Nov 3.

Department of Psychology, University of Maryland, Baltimore County, 1000 Hilltop Circle, Baltimore, MD 21250, USA. Electronic address:

Well-validated screening tools have been developed to identify people at high risk for psychosis, but these are rarely used outside of specialty clinics or research settings. The development of extremely brief and simple screening tools could increase dissemination, especially in settings with low buy-in such as those with low base rates of psychosis and/or time constraints. We sought to identify such a brief measure by modeling participant responses to three psychosis screening questionnaires (Prime Screen; Prodromal Questionnaire-Brief; Youth Psychosis At Risk Questionnaire) in a sample of 139 help-seeking individuals and 335 college students (age range: 12-25). Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01651781183148
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http://dx.doi.org/10.1016/j.psychres.2018.11.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6296822PMC
December 2018
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Masked ambiguity - Emotion identification in schizophrenia and major depressive disorder.

Psychiatry Res 2018 Dec 28;270:852-860. Epub 2018 Oct 28.

Department of Psychology, Kawamura Gakuen Women's University, Faculty of Liberal Arts, 1133 Sageto, Abiko-city, Chiba 270-1138, Japan. Electronic address:

Both patients with schizophrenia and with a major depressive disorder (MDD) display deficits in identifying facial expressions of emotion during acute phases of their illness. However, specific deficit patterns have not yet been reliably demonstrated. Tasks that employ emotionally ambiguous stimuli have recently shown distinct deficit patterns in patients with schizophrenia compared to other mental disorders as well as healthy controls. Read More

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http://dx.doi.org/10.1016/j.psychres.2018.10.042DOI Listing
December 2018
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Construing and body dissatisfaction in chronic depression: A study of body psychotherapy.

Psychiatry Res 2018 Dec 30;270:845-851. Epub 2018 Oct 30.

Wolfson Institute of Preventive Medicine, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK. Electronic address:

The frequent association of depression with somatic symptoms suggests that body psychotherapy may be an appropriate therapeutic intervention for people with chronic depression. Using a subset of twenty-three participants from a randomized controlled trial that had demonstrated the effectiveness of such an intervention in reducing depressive symptoms, the present study investigated whether it may also impact aspects of construing which have been associated with depression. Patients presenting with chronic depression were randomly allocated to a treatment group or a waiting list group, which received body psychotherapy after a period on a waiting list. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01651781183067
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http://dx.doi.org/10.1016/j.psychres.2018.10.061DOI Listing
December 2018
1 Read

Gout and the risk of incident depression in older adults.

Psychiatry Res 2018 Dec 30;270:842-844. Epub 2018 Oct 30.

Department of Medicine at School of Medicine, USA. Electronic address:

We used the 5% random Medicare claims from Americans 65 years or older from 2006-2012 to examine the association of gout with the risk of developing incident (new) depression using multivariable-adjusted Cox proportional hazards model, adjusting for demographics (age, race, sex), common cardiovascular medications, allopurinol, and febuxostat and medical comorbidity. Of the 1.69 million people, 142,596 developed depression. Read More

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http://dx.doi.org/10.1016/j.psychres.2018.10.067DOI Listing
December 2018

The relationship between coping style and Internet addiction among mainland Chinese students: A meta-analysis.

Psychiatry Res 2018 Dec 31;270:831-841. Epub 2018 Oct 31.

Special Education Department, School of Education, Guangzhou University, Guangzhou, People's Republic of China. Electronic address:

The matter of whether different coping styles are correlated with increased Internet addiction or not remains a topic of debate. Most researchers have argued that Internet addiction is linked to low positive coping and high negative coping; however, others have rejected this opinion. Consequently, this meta-analysis examined the link between coping style and Internet addiction to address this controversy. Read More

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http://dx.doi.org/10.1016/j.psychres.2018.10.079DOI Listing
December 2018

Assessment of perceived mental health-related stigma: The Stigma-9 Questionnaire (STIG-9).

Psychiatry Res 2018 Dec 10;270:822-830. Epub 2018 Oct 10.

Department of Psychosomatic Medicine and Psychotherapy, University Medical Centre Hamburg-Eppendorf, Germany. Electronic address:

Mental health-related stigma is common and inhibits help-seeking. It triggers fears of devaluation and can add to the burden of a mental disorder. To counter the consequences of mental health-related stigma, its sound assessment is crucial. Read More

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http://dx.doi.org/10.1016/j.psychres.2018.10.026DOI Listing
December 2018

The spark that might have ignited the fire: The association of cognitive and psychological factors with state anxiety in light of the Syrian-Israeli incident.

Psychiatry Res 2018 Dec 28;270:815-821. Epub 2018 Oct 28.

School of Social Work, Ariel University, Ariel, 40700, Israel. Electronic address:

The current study aimed to explore Israelis' state anxiety due to a Syrian-Israeli incident that occurred on February 10, 2018, when an Israeli F-16 fighter jet was shot down by Syrian air defense forces. In line with the "looming vulnerability" model which emphasizes the importance of the dynamic nature of psychologically threatening situations, the following psychological factors were suggested: associative memory of prior events, worries of future war, sense of safety, and death anxiety. We employed two cross-sectional points of time in our assessment: 36 hours and three months after the incident. Read More

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http://dx.doi.org/10.1016/j.psychres.2018.10.072DOI Listing
December 2018

Enhancing the understanding of clinically meaningful results: A clinical research perspective.

Psychiatry Res 2018 Dec 31;270:801-806. Epub 2018 Oct 31.

Child Study Center, Yale University School of Medicine, New Haven, USA; Department of Biometry, Yale Home Office, North Branford, USA. Electronic address:

Published research often address aspects related to "statistical significance" but fail to address the clinical and practical importance and meaning of results. Our main objectives in this article are to investigate the merit of common measures of Effect Size in statistical research and to highlight the importance of the simple Relative Risk ratio. In this article we present data where we consider two widely utilized effect size measures (Cohen's d and Pearson's r) in relations to relative risk. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01651781183026
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http://dx.doi.org/10.1016/j.psychres.2018.10.069DOI Listing
December 2018
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How the use of the term "schizo*" has changed in an Italian newspaper from 2001 to 2015: Findings from a descriptive analysis.

Psychiatry Res 2018 Dec 31;270:792-800. Epub 2018 Oct 31.

Department of Psychiatry, Università degli Studi della Campania "Luigi Vanvitelli", Largo Madonna delle Grazie, 1, 80138 Napoli, Italy.

The study aims to report the number of newspaper articles including the word "schizo" in the period 2001 - 2015 and to identify possible predictors reinforcing negative stereotypes about people with schizophrenia. The electronic archives of the Italian newspaper "La Stampa" have been searched for the term "schizo". Selected articles were grouped in articles related to mental health (rMH) or article not related to mental health (nrMH). Read More

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http://dx.doi.org/10.1016/j.psychres.2018.10.076DOI Listing
December 2018

Retinal nerve fiber layer thickness changes in Schizophrenia: A meta-analysis of case-control studies.

Psychiatry Res 2018 Dec 30;270:786-791. Epub 2018 Oct 30.

Department of Ophthalmology, Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, No. 26 Shengli Street, Hubei Province, Wuhan 430014, China. Electronic address:

Studies using optical coherence tomography (OCT) to compare retinal nerve fiber layer thickness in subjects with schizophrenia and healthy controls have yielded inconsistent results. We aimed to compare changes in retinal nerve fiber layer thickness in schizophrenia and healthy controls via a meta-analysis. Relevant studies were selected via an electronic search of the Cochrane Controlled Trials Register, Pubmed, and Embase. Read More

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http://dx.doi.org/10.1016/j.psychres.2018.10.075DOI Listing
December 2018

Comorbidity of Attention Deficit Hyperactivity Disorder and Generalized Anxiety Disorder in children and adolescents.

Psychiatry Res 2018 Dec 31;270:780-785. Epub 2018 Oct 31.

Department of Human Sciences, Roma Tre University, Rome, Italy.

The aim of the study is to explore the impact of Generalized Anxiety Disorder (GAD) comorbidity in children with Attention Deficit Hyperactivity Disorder (ADHD). Six hundred children with ADHD (mean age = 9.12 years), recruited from 2013 to 2017, participated in the study. Read More

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http://dx.doi.org/10.1016/j.psychres.2018.10.078DOI Listing
December 2018

The inflammasome NLRP12 is associated with both depression and coronary artery disease in Vietnam veterans.

Psychiatry Res 2018 Dec 27;270:775-779. Epub 2018 Oct 27.

School of Psychology and Counselling, Faculty of Health, Institute of Health and Biomedical Innovation, Queensland University of Technology, Kelvin Grove, Queensland, Australia.

Several studies have established that Major depressive disorder is associated with excess inflammation with an elevation of both pro and anti-inflammatory cytokines in major depressive disorder. In addition, individuals with major depressive disorder are at higher risk of developing coronary artery disease. The role of innate immunity and NFκB-mediated inflammation in depression and its increased association with coronary artery disease is yet to be fully elucidated. Read More

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http://dx.doi.org/10.1016/j.psychres.2018.10.051DOI Listing
December 2018
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Problem behaviours and Major Depressive Disorder in adults with intellectual disability and autism.

Psychiatry Res 2018 Dec 15;270:769-774. Epub 2018 Oct 15.

CREA (Research and Clinical Centre), San Sebastiano Foundation, Florence Italy. Electronic address:

The high prevalence of Problem Behaviours (PB) in persons with intellectual disability (ID) and Autism Spectrum Disorder (ASD) has been associated by some researchers to a proportionate frequency of Major Depressive Disorder (MDD), which have a different presentation in persons with ID and ASD than in the general population, mostly as behavioural changes. Nevertheless, evidence on this behavioural equivalency is still scarce. The present study aims at evaluating the rate of MDD in persons with ID and ASD presenting PB. Read More

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http://dx.doi.org/10.1016/j.psychres.2018.10.039DOI Listing
December 2018
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Looking through autistic features in schizophrenia using the PANSS Autism Severity Score (PAUSS).

Psychiatry Res 2018 Dec 29;270:764-768. Epub 2018 Oct 29.

Department of Mental Health and Addiction Services, ASST-Spedali Civili, Brescia, Italy; Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.

Autism spectrum disorder (ASD) and schizophrenia share several features. However, the assessment of ASD in schizophrenia is difficult. Aim of this study is to investigate the possibility to use the PANSS Autism Severity Score (PAUSS) to recognize autistic features in schizophrenia. Read More

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http://dx.doi.org/10.1016/j.psychres.2018.10.074DOI Listing
December 2018

Beyond diagnosis: Mentalization and mental health from a transdiagnostic point of view in adolescents from non-clinical population.

Psychiatry Res 2018 Dec 21;270:755-763. Epub 2018 Oct 21.

Department of Clinical and Health Psychology, Universitat Autònoma de Barcelona, Barcelona, Catalonia, Spain; Department of Mental Health. Fundació Sanitària Sant Pere Claver, Barcelona, Catalonia, Spain; Centre for Biomedical Research Network on Mental Health (CIBERSAM), Instituto de Salud Carlos III, Madrid, Spain.

An increasing volume of evidence suggests that mentalization (MZ) can be an important factor in the transition from mental health to mental illness and vice versa. However, most studies are focused on the role of MZ in specific disorders. This study aims to evaluate the relationship between MZ and mental health as a trans-diagnostic process. Read More

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http://dx.doi.org/10.1016/j.psychres.2018.10.048DOI Listing
December 2018

Factors predicting re-hospitalization for inpatients with bipolar mania--A naturalistic cohort.

Psychiatry Res 2018 Dec 30;270:749-754. Epub 2018 Oct 30.

Kaohsiung Municipal Kai-Syuan Psychiatric Hospital, Kaohsiung, Taiwan. Electronic address:

Patients with bipolar mania often require re-hospitalization, which can be a social-economic burden. This study aimed to investigate the factors affecting time to re-hospitalization for inpatients with acute bipolar mania. In this 6-year naturalistic study we reviewed the charts of inpatients with acute bipolar mania. Read More

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http://dx.doi.org/10.1016/j.psychres.2018.10.073DOI Listing
December 2018

Impact of physical or sexual childhood abuse on plasma DHEA, DHEA-S and cortisol in a low-dose dexamethasone suppression test and on cardiovascular risk parameters in adult patients with major depression or anxiety disorders.

Psychiatry Res 2018 Dec 26;270:744-748. Epub 2018 Oct 26.

University Hospital Hamburg-Eppendorf, Department of Psychiatry and Psychotherapy, Hamburg, Germany.

While the impact of childhood trauma on basal and dynamic cortisol regulation has widely been studied, the most abundant steroid hormones dehydroepiandrosterone (DHEA) and its sulphated derivative DHEA-S have received little attention in this context. One-hundred in-door patients suffering from major depression or an anxiety disorder filled in the Childhood Trauma Questionaire. A low dose dexamethasone suppression test (DST) measuring DHEA, DHEA-S and cortisol was performed. Read More

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http://dx.doi.org/10.1016/j.psychres.2018.10.068DOI Listing
December 2018