12,729 results match your criteria Psychiatry Research: Neuroimaging [Journal]


Longitudinal diffusion weighted imaging of limbic regions in patients with major depressive disorder after 6 years and partial to full remission.

Psychiatry Res Neuroimaging 2019 Apr 12;287:75-86. Epub 2019 Apr 12.

Department of Psychiatry and Psychotherapy, Otto von Guericke University, 39120 Magdeburg, Germany.

The objective of this study was to determine the effect of major depressive disorder (MDD) on white matter microstructures after a 6-year period compared to healthy controls (HC). This study included a small sample size of 26 participants, including 14 patients with MDD clinically diagnosed at baseline, and 12 HCs. MRI brain scans were conducted at baseline and follow-up, 75. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S09254927183026
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http://dx.doi.org/10.1016/j.pscychresns.2019.04.004DOI Listing
April 2019
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Validation of the social functioning scale: Comparison and evaluation in early psychosis, autism spectrum disorder and social anxiety disorder.

Psychiatry Res 2019 Mar 26;276:45-55. Epub 2019 Mar 26.

Autism Clinic for Translational Research, Brain and Mind Centre, Central Clinical School, Faculty of Medicine, University of Sydney, Camperdown, Sydney, NSW 2050 Australia. Electronic address:

Social functioning is an important component of mental disorders for assessment and treatment. There is no recognised self-report instrument to measure social functioning across disorders where social impairment is significant. The Social Functioning Scale (SFS) has, however, been used to assess social functioning in psychotic disorders, including Schizophrenia and Early Psychosis. Read More

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http://dx.doi.org/10.1016/j.psychres.2019.03.037DOI Listing

How to assess negative affective reactivity to daily life stress in depressed and nondepressed individuals?

Psychiatry Res 2019 Apr 16. Epub 2019 Apr 16.

University of Groningen, University Medical Center Groningen, Department of Psychiatry, Interdisciplinary Center Psychopathology and Emotion regulation (ICPE), CC72, P.O. Box 30.001, 9700 RB Groningen, The Netherlands; Center for Integrative Psychiatry, Lentis, Groningen, The Netherlands.

Intensive longitudinal data studies on affective reactivity to daily life stress have used various dimensions of stress. Based on an evidence-based conceptual model of stress, the current study included unpredictability, uncontrollability and unpleasantness, and examined whether and how these predict affective reactivity in depressed and non-depressed individuals in daily life. Participants (27 depressed, 27 non-depressed) completed a diary 3 times a day for a period of 30 days. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01651781183149
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http://dx.doi.org/10.1016/j.psychres.2019.03.040DOI Listing
April 2019
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Mental health literacy for autism spectrum disorder and depression.

Psychiatry Res 2019 Apr 16. Epub 2019 Apr 16.

Norwegian Business School (BI), Nydalveien, Olso, Norway. Electronic address:

In this study, three hundred and sixty-eight participants answered a questionnaire consisting of three vignettes describing a person with depression, severe Autism Spectrum Disorder (ASD), and high-functioning Autism Spectrum Disorder/Asperger's Syndrome (AS). Each vignette was followed by thirteen questions concerning the participant's knowledge about diagnosis, treatment, and prognosis. Participants demonstrated good mental health literacy (MHL) for depression, but were poor at diagnosing ASD. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01651781193003
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http://dx.doi.org/10.1016/j.psychres.2019.04.004DOI Listing
April 2019
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A comparison of potential psychiatric drug interactions from six drug interaction database programs.

Psychiatry Res 2019 Mar 25;275:366-372. Epub 2019 Mar 25.

ChronoRecord Association, Fullerton, CA, USA.

Harmful drug-drug interactions (DDI) frequently include psychiatric drugs. Drug interaction database programs are viewed as a primary tool to alert physicians of potential DDI, but may provide different results as there is no standard to define DDI. This study compared the category of potential DDI provided by 6 commercial drug interaction database programs (3 subscription, 3 open access) for 100 drug interaction pairs. Read More

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http://dx.doi.org/10.1016/j.psychres.2019.03.041DOI Listing

Brain volumes and their ratios in Alzheimer´s disease on magnetic resonance imaging segmented using Freesurfer 6.0.

Psychiatry Res Neuroimaging 2019 Mar 19;287:70-74. Epub 2019 Mar 19.

National Institute of Mental Health, Topolová 748, Klecany 250 67, Czechia; Institute of Clinical and Experimental Medicine, Czechia.

Ratios between opposing volumes from brain magnetic resonance imaging (MRI) can provide additional information to volumes in Alzheimer's disease (AD). Brain three-dimensional MPRAGE MRI at 3T were segmented into 44 regions using FreeSurfer v6 in 75 participants. The region's size in absolute volumes and relative proportions to the whole brain volume were compared between 39 AD patients and 36 age-, education- and sex-matched normal controls (NC). Read More

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http://dx.doi.org/10.1016/j.pscychresns.2019.01.014DOI Listing

Effect of selective serotonin reuptake inhibitors on markers of bone loss.

Psychiatry Res 2019 Apr 3;276:39-44. Epub 2019 Apr 3.

Pharmaceutical Medicine, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi 110062, India; Department of Pharmacology, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi 110062, India. Electronic address:

Several preclinical and clinical studies show that selective serotonin reuptake inhibitors (SSRI's) are associated with bone loss and an increase in fracture risk, not many reports on their effect on bone turnover markers. This cross-sectional study evaluated the effect of SSRIs treatment on bone turnover markers in Indian population for the first time. Inclusion criteria were subjects of either sex and age 18-45 years undergoing treatment with an SSRI for at least 3 months, regardless of the indication. Read More

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http://dx.doi.org/10.1016/j.psychres.2019.04.006DOI Listing

The effect of testosterone therapy on personality traits of trans men: a controlled prospective study in Germany and Switzerland.

Psychiatry Res 2019 Apr 1;276:31-38. Epub 2019 Apr 1.

Department of Consultation-Liaison-Psychiatry and Psychosomatic Medicine, University Hospital Zurich, Rämistrasse 100, 8002 Zürich, Switzerland.

Gender dysphoria in transgender men is generally treated with exogenous testosterone administration aiming to suppress secondary female sex characteristics and achieve masculinization. However, the effect of testosterone on the personality of transgender men remains largely unknown. Therefore, we conducted a controlled study with 23 trans men (M = 27. Read More

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http://dx.doi.org/10.1016/j.psychres.2019.03.053DOI Listing
April 2019
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Post-traumatic stress disorder and asthma risk: A nationwide longitudinal study.

Psychiatry Res 2019 Apr 10;276:25-30. Epub 2019 Apr 10.

Department of Psychiatry, Taipei Veterans General Hospital, Taipei, Taiwan; Department of Psychiatry, College of Medicine, National Yang-Ming University, Taipei, Taiwan. Electronic address:

Background: Increasing evidence suggests that post-traumatic stress disorder (PTSD) interferes with the immunological system and is correlated with cardiovascular disease, respiratory disease, and chronic pain conditions. However, the association between PTSD and asthma remains unknown.

Methods: A total of 5518 patients with PTSD and 22,072 age- and sex-matched healthy individuals were enrolled between 2001 and 2009 and followed until the end of 2011. Read More

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http://dx.doi.org/10.1016/j.psychres.2019.04.014DOI Listing
April 2019
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Increased [³H]quisqualic acid binding density in the dorsal striatum and anterior insula of alcoholics: A post-mortem whole-hemisphere autoradiography study.

Psychiatry Res Neuroimaging 2019 Apr 8;287:63-69. Epub 2019 Apr 8.

Department of Psychiatry, Kuopio University Hospital, P.O. Box 100, FI-70029 Kuopio, Finland.

The function of group I metabotropic glutamate receptors mGluR1 and mGluR5 is involved in the hyperglutamatergic state caused by chronic alcohol. Preclinical studies suggest that group I mGluR modulation could serve as a novel treatment of alcoholism. Considering the wide role of glutamatergic neurochemistry in addiction, group I mGluR binding was studied in brain areas involved in decision-making, learning and memory. Read More

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http://dx.doi.org/10.1016/j.pscychresns.2019.04.002DOI Listing
April 2019
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Amygdalar volume and violent ideation in a sample at clinical high-risk for psychosis.

Psychiatry Res Neuroimaging 2019 Apr 11;287:60-62. Epub 2019 Apr 11.

Columbia University, Department of Psychiatry, New York State Psychiatric Institute (NYSPI), 1051 Riverside Drive, Unit 31, New York, NY 10032, USA. Electronic address:

We previously demonstrated that violent ideation predicts both violent acts and eventual progression to syndromal psychosis in individuals at clinical high-risk for psychosis (CHR). We performed amygdalar surface morphometry analysis on MRI scans from 70 CHR individuals, 21 of whom had violent ideation, 49 of whom did not. CHR individuals with violent ideation have abnormal and asymmetric amygdalar volumes. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S09254927193001
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http://dx.doi.org/10.1016/j.pscychresns.2019.04.003DOI Listing
April 2019
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The effect of N-acetylcysteine and working memory training on neural mechanisms of working memory and cue reactivity in regular cocaine users.

Psychiatry Res Neuroimaging 2019 Apr 5;287:56-59. Epub 2019 Apr 5.

Addiction, Development, and Psychopathology (ADAPT) lab, Department of Psychology, University of Amsterdam, Amsterdam, the Netherlands.

The current study investigated the combined effects of N-acetylcysteine and working memory (WM) training on behavioral and neural mechanisms of cue reactivity and WM in cocaine users in a randomized, double-blind design. Twenty-four of 38 cocaine-using men completed a 25-day treatment with either 2400 mg/day NAC or placebo. Both groups performed WM-training. Read More

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http://dx.doi.org/10.1016/j.pscychresns.2019.03.011DOI Listing

Microstructural correlates of Edinburgh Cognitive and Behavioural ALS Screen (ECAS) changes in amyotrophic lateral sclerosis.

Psychiatry Res Neuroimaging 2019 Apr 2. Epub 2019 Apr 2.

Department of Psychology, University of Campania "Luigi Vanvitelli", Caserta, Italy.

Edinburgh Cognitive and Behavioural ALS Screen (ECAS) was designed for testing patients with amyotrophic lateral sclerosis (ALS), a multi-system neurodegenerative disease characterized by progressive physical disability. In this study, we aim to explore the potential brain microstructural substrates associated with performance on ECAS in the early stages of ALS, using a whole-brain tract-based spatial statistics diffusion tensor imaging approach. Thirty-six non-demented ALS patients, assessed using ECAS, and 35 age-, sex- and education-matched healthy controls underwent magnetic resonance imaging at 3 Tesla. Read More

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http://dx.doi.org/10.1016/j.pscychresns.2019.04.001DOI Listing
April 2019
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Addendum to Abplanalp, S., and Fulford, D. (2019). Physical effort exertion and pain: Links with trait-based risk for psychopathology. Psychiatry Research, 271 (2019), 46-51.

Psychiatry Res 2019 Apr 8. Epub 2019 Apr 8.

Sargent College of Health & Rehabilitation Sciences, Boston University, Boston, MA 02215, United States. Electronic address:

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http://dx.doi.org/10.1016/j.psychres.2019.04.011DOI Listing

Parental threats and adolescent depression: The role of emotion dysregulation.

Psychiatry Res 2019 Apr 5;276:18-24. Epub 2019 Apr 5.

Department of Psychology, University of Houston, Houston, TX 77204, USA; Department of Behavioral Science, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

Childhood exposure to parental threatening behaviors places adolescents at greater risk for depression. However, the association between parental threatening behaviors and depressive symptoms among trauma-exposed inpatient youth, and potential factors that exacerbate the harmful effects of such parenting, have remained unexplored. One factor that may contribute to depression is low emotional clarity, which is characterized by difficulties recognizing and understanding one's emotions. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01651781193040
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http://dx.doi.org/10.1016/j.psychres.2019.04.009DOI Listing
April 2019
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Cardiopulmonary coupling analysis predicts early treatment response in depressed patients: A pilot study.

Psychiatry Res 2019 Apr 2;276:6-11. Epub 2019 Apr 2.

Department of Sleep Medicine, Shenzhen Kangning Hospital, No. 1080 Cuizhu Road, Shenzhen, Guangdong 518020, China. Electronic address:

This pilot study evaluated the effect of anti-depression treatment on sleep quality and symptoms of depression in patients with major depressive disorder, and identified cardiopulmonary coupling (CPC) indices for predicting early response. Forty-one Han Chinese patients with major depressive disorder were assessed for objective sleep quality before treatment (baseline) and at 2 weeks using CPC. Subjective sleep quality and depression levels were measured at baseline and 2 and 4 weeks after treatment, using the 24-item Hamilton Rating Scale for Depression (HAMD-24), Epworth Sleepiness Scale (ESS), and Pittsburgh Sleep Quality Index (PSQI). Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01651781183209
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http://dx.doi.org/10.1016/j.psychres.2019.04.002DOI Listing
April 2019
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Symptoms, course of Illness, and comorbidity as predictors of expressed emotion in bipolar disorder.

Psychiatry Res 2019 Mar 30;276:12-17. Epub 2019 Mar 30.

McGovern Medical School, Department of Psychiatry and Behavioral Sciences, University of Texas HSC at Houston, 1941 East Road (BBSB 3118), Houston, Texas 77054, USA. Electronic address:

High levels of expressed emotions (EE) reflect the amount of criticism and/or over-involvement in families and has been linked to relapse risk in various psychiatric disorders including bipolar disorder (BD). Less clear is which factors contribute to the development and/or maintenance of EE. Therefore, we tested whether patient characteristics, specifically clinical features and personality disorder traits in BD predicted key aspects of EE as assessed by patients and their relatives. Read More

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http://dx.doi.org/10.1016/j.psychres.2019.03.049DOI Listing
March 2019
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Obsessive-compulsive symptoms in patients with schizophrenia: Relationships with olanzapine pharmacological parameters, psychopathology, and quality of life.

Psychiatry Res 2019 Mar 6;276:1-5. Epub 2019 Mar 6.

Department of Psychiatry, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan; Department of Psychiatry, Wan-Fang Hospital, Taipei Medical University, No. 111, Sec. 3, Hsin-Long Rd, Taipei 116, Taiwan; Psychiatric Research Center, Wan-Fang Hospital, Taipei Medical University, Taipei, Taiwan. Electronic address:

Obsessive-compulsive symptoms (OCS) occur in a substantial portion of schizophrenia patients and have significant impacts on clinical course. This study was intended to investigate the relationships of OCS with pharmacological parameters of olanzapine, psychopathology, and quality of life. Totally 151 schizophrenia patients were recruited, and rated using Yale-Brown Obsessive-Compulsive scale (YBOCS), Positive and Negative Syndrome Scale (PANSS), Montgomery-Åsberg Depression Rating Scale (MADRS), and World Health Organization Questionnaire on Quality of Life: Short Form (WHOQOL-BREF). Read More

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http://dx.doi.org/10.1016/j.psychres.2019.03.007DOI Listing

Dendrite complexity of the posterior cingulate cortex as a substrate for recovery from post-stroke depression: A pilot study.

Psychiatry Res Neuroimaging 2019 Mar 18;287:49-55. Epub 2019 Mar 18.

Department of Neurology, National Cerebral and Cardiovascular Center, Suita, Japan.

The neural basis of recovery from a depressive state remains poorly understood. The main purpose of this study was to determine the neural basis of vulnerability/resilience to depression in stroke patients in terms of changes in regional microstructure. The study included 20 individuals with acute ischaemic stroke. Read More

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http://dx.doi.org/10.1016/j.pscychresns.2019.01.015DOI Listing
March 2019
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Assessment of the revised Difficulties in Emotion Regulation Scales among adolescents and adults with severe mental illness.

Psychiatry Res 2019 Apr 8. Epub 2019 Apr 8.

Department of Psychology, University of Hawaii, HI, United States.

The Difficulties in Emotion Regulation Scale (DERS) comprising 36 items has been widely used across age, gender, psychopathology, language, and culture. Recently several alternative abridged forms have been introduced, namely, the DERS-16 (Bjureberg et al. 2016), the DERS-SF (Kaufman et al. Read More

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http://dx.doi.org/10.1016/j.psychres.2019.04.010DOI Listing

Predictors of concurrent depressive symptoms in patients with obsessive-compulsive disorder.

Psychiatry Res 2019 Apr 4. Epub 2019 Apr 4.

Rogers Memorial Hospital, Oconomowoc, WI, USA.

Many patients with obsessive-compulsive disorder (OCD) exhibit concurrent depressive symptoms, which are associated with negative psychological outcomes. Yet little research has focused on identifying factors that predict depressive symptoms in OCD. The current study examined three transdiagnostic constructs-anxiety sensitivity (AS), intolerance of uncertainty (IU), and worry-as predictors of depressive symptom severity in a sample of treatment-seeking adults with a primary diagnosis of OCD (N = 93). Read More

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http://dx.doi.org/10.1016/j.psychres.2019.03.052DOI Listing
April 2019
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Measuring facets of reward sensitivity, inhibition, and impulse control in individuals with problematic Internet use.

Psychiatry Res 2019 Mar 19;275:351-358. Epub 2019 Mar 19.

Northwestern University, Department of Psychology, Department of Psychiatry, Department of Medical Social Sciences, Institute for Policy Research, and Institute for Innovations in Developmental Sciences, 2029 Sheridan Road, Evanston, IL 60208, United States. Electronic address:

Introduction: Problematic Internet Use (PIU) is the inability to control the amount of time spent on the Internet. Research indicates that abnormalities in reward sensitivity, sensitivity to punishment, and impulse control drive addictive behaviors such as substance abuse and gambling disorders, but it is unclear whether this is also the case in PIU.

Methods: Behavioral tasks and scales were completed by 62 participants (32 PIU individuals and 30 no-PIU individuals) to assess reward sensitivity, sensitivity to punishment, as well as inhibitory function and impulse control. Read More

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http://dx.doi.org/10.1016/j.psychres.2019.03.032DOI Listing
March 2019
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Humour processing deficits in individuals with social anhedonia.

Psychiatry Res 2019 Apr 3;275:345-350. Epub 2019 Apr 3.

Neuropsychology and Applied Cognitive Neuroscience Laboratory, CAS Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, Beijing, China; Department of Psychology, University of Chinese Academy of Sciences, Beijing, China.

Humour processing comprises the humour comprehension and the humour appreciation phases. Patients with schizophrenia have impaired humour processing. However, it is unclear whether such deficits affect subclinical populations such as individuals with social anhedonia. Read More

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http://dx.doi.org/10.1016/j.psychres.2019.04.005DOI Listing
April 2019
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Negative symptoms and recollections of parental rejection: The moderating roles of psychological maladjustment and gender.

Psychiatry Res 2019 Mar 25;275:332-337. Epub 2019 Mar 25.

Department of Psychology, Ankara University, Turkey. Electronic address:

The aim of the study was to investigate the moderating roles of the current self-reported psychological maladjustment and gender in the relationship between perceived parental rejection in childhood and negative symptoms of schizophrenia patients. The study sample consisted of 52 outpatients (20 females and 32 males between the ages of 19 and 61), diagnosed with schizophrenia at Ankara University and Ege University Faculty of Medicine Department of Psychiatry in Turkey. Participants' negative symptoms, recollections of parental rejection, and psychological maladjustment were assessed by Scale for the Assessment of Negative Symptoms, Adult Parental Acceptance-Rejection Questionnaire, and Personality Assessment Questionnaire, respectively. Read More

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http://dx.doi.org/10.1016/j.psychres.2019.03.042DOI Listing
March 2019
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Posttraumatic stress symptoms in people exposed to the 2017 earthquakes in Mexico.

Psychiatry Res 2019 Apr 2;275:326-331. Epub 2019 Apr 2.

Postgraduate Department, University of Sierra Sur, Oaxaca, Mexico.

This is the first study to produce a reliable valid measure of the symptoms of Posttraumatic Stress Disorders (PTSD) in Mexico, which has a high incidence of disasters, and has not had a measurement of PTSD frequency in the population. The objective was to analyze the prevalence of PTSD symptoms in persons who experienced the 2017 earthquakes in Mexico. A probabilistic sample of 1539 participants from Mexico City, the State of Mexico, Chiapas, Puebla, Morelos and Oaxaca during November and December of 2017 was screened using the Davidson Trauma Scale (DTS) for symptoms of post-traumatic stress. Read More

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http://dx.doi.org/10.1016/j.psychres.2019.04.003DOI Listing
April 2019
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Distinguishing prodromal stage of bipolar disorder and early onset schizophrenia spectrum disorders during adolescence.

Psychiatry Res 2019 Apr 1;275:315-325. Epub 2019 Apr 1.

Ege University School of Medicine, Department of Child and Adolescent Psychiatry, Izmir, Turkey.

Prodromal symptoms of bipolar disorder (BD) and early onset schizophrenia spectrum disorder (EOSSD) overlap. To date, there has been no study directly comparing the prodromal stage of both disorders. Thus, the current study is aimed at determining which prodromal symptom clusters differentiate BD and EOSSD. Read More

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http://dx.doi.org/10.1016/j.psychres.2019.03.051DOI Listing
April 2019
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Anxiety symptoms across twenty-years in schizoaffective disorder, bipolar disorder, and major depressive disorder.

Psychiatry Res 2019 Mar 30;275:310-314. Epub 2019 Mar 30.

Department of Psychiatry, University of Illinois-Chicago, Chicago, IL, USA.

Anxiety symptoms and anxiety disorders are common in both mood and psychotic disorders. However, limited comparative information exists regarding the long-term course of anxiety in schizoaffective disorder, bipolar disorder, and major depressive disorder. Prospective evaluation of the 20-year trajectory of self-reported anxiety and somatic-related anxiety in three major diagnostic groups, 43 schizoaffective patients, 47 bipolar patients, and 109 major depression patients was conducted. Read More

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http://dx.doi.org/10.1016/j.psychres.2019.03.050DOI Listing
March 2019
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Social anxiety as a precursor for depression: Influence of interpersonal rejection and attention to emotional stimuli.

Psychiatry Res 2019 Apr 1;275:296-303. Epub 2019 Apr 1.

Department of Psychology, Oklahoma State University, 116 N Murray Hall, Stillwater, OK 74078, United States.

Social anxiety disorder (SAD) and major depressive disorder (MDD) are comorbid conditions, and SAD confers risk for MDD. Biased attention and interpersonal rejection are important for the development of SAD and MDD, but little research has examined how these processes may lead to MDD. We hypothesized that interpersonal rejection would result in SAD symptoms being associated with more "depression-like" attention biases. Read More

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http://dx.doi.org/10.1016/j.psychres.2019.04.001DOI Listing
April 2019
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Mental health in spouses of U.S. Gulf War veterans.

Psychiatry Res 2019 Mar 27;275:287-295. Epub 2019 Mar 27.

School of Medicine, Washington University, St. Louis, MO, USA.

Veterans' spouses are at risk for mental distress and substance use. We examined long term psychological functioning in spouses from a national cohort of 1991 Gulf War era veterans. From clinical interviews, spouses of deployed veterans (n = 488) did not have a greater prevalence of post-war mental disorders compared to spouses of non-deployed veterans (n = 536); however, in couples that were living together since the war, there was an increased risk of anxiety disorders or any one disorder. Read More

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http://dx.doi.org/10.1016/j.psychres.2019.03.043DOI Listing
March 2019
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Functional analyses and effect of DNA methylation on the EGR1 gene in patients with schizophrenia.

Psychiatry Res 2019 Mar 26;275:276-282. Epub 2019 Mar 26.

Department of Psychiatry, Yuli Branch, Taipei Veterans General Hospital, Hualien County, Taiwan. Electronic address:

EGR1, involved in the regulation of synaptic plasticity, learning, and memory, is considered a candidate gene for schizophrenia. We resequenced the exonic regions of EGR1 in 516 patients with schizophrenia and conducted a reporter gene assay. We found two mutations including a rare mutation (c. Read More

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http://dx.doi.org/10.1016/j.psychres.2019.03.044DOI Listing
March 2019
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Cortisol levels before and after cognitive behavioural therapy in patients with eating disorders reporting childhood abuse: A follow-up study.

Psychiatry Res 2019 Mar 28;275:269-275. Epub 2019 Mar 28.

Psychiatry Unit, Department of Health Sciences, University of Florence, Italy.

The etiopathogenesis of eating disorders (EDs) is complex and still not well understood. Biological, psychological and environmental factors (e.g. Read More

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http://dx.doi.org/10.1016/j.psychres.2019.03.046DOI Listing
March 2019
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Cerebellar white matter in young adults with a familial risk for psychosis.

Psychiatry Res Neuroimaging 2019 Mar 23;287:41-48. Epub 2019 Mar 23.

Department of Psychiatry, Research Unit of Clinical Neuroscience, University of Oulu, Oulu, Finland; Department of Psychiatry, Oulu University Hospital, Oulu, Finland; Medical Research Center Oulu, Oulu University Hospital and University of Oulu, Finland.

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http://dx.doi.org/10.1016/j.pscychresns.2019.03.012DOI Listing

Network neurobiology of electroconvulsive therapy in patients with depression.

Psychiatry Res Neuroimaging 2019 Mar 20;287:31-40. Epub 2019 Mar 20.

Department of Neuroimaging and Interventional Radiology, National Institute of Mental Health and Neurosciences (NIMHANS), Hosur Road, Bangalore 560029, India; Cognitive Neuroscience Centre, National Institute of Mental Health and Neurosciences (NIMHANS), Hosur Road, Bangalore 560029, India. Electronic address:

Graph theory, a popular analytic tool for resting state fMRI (rsfMRI) has provided important insights in the neurobiology of depression. We aimed to analyze the changes in the network measures of segregation and integration associated with the administration of ECT in patients with depression and to correlate with both clinical response and cognitive deficits. Changes in normalised clustering coefficient (γ), path length (λ) and small-world (σ) index were explored in 17 patients with depressive episode before 1st and after 6th brief-pulse bifrontal ECT (BFECT) sessions. Read More

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http://dx.doi.org/10.1016/j.pscychresns.2019.03.008DOI Listing
March 2019
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A pilot randomized trial of a dual n-back emotional working memory training program for veterans with elevated PTSD symptoms.

Psychiatry Res 2019 Feb 7;275:261-268. Epub 2019 Feb 7.

Department of Psychology, University of Wisconsin-Milwaukee, 2441 E Hartford Ave., Milwaukee, WI 53211, USA. Electronic address:

Anxiety is characterized by excessive attention to threatening information, leading to impaired working memory (WM) performance and elevated anxious thoughts. Preliminary research indicates that individuals with PTSD show particular difficulty with WM in emotional contexts (Schweizer et al., 2011). Read More

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http://dx.doi.org/10.1016/j.psychres.2019.02.015DOI Listing
February 2019
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State and trait neural correlates of the balance between work and nonwork roles.

Psychiatry Res Neuroimaging 2019 Mar 20;287:19-30. Epub 2019 Mar 20.

Department of Psychology, University of Winchester, Sparkford Road, Winchester, Hampshire SO22 4NR, UK; Department of Psychology, Institute of Human Sciences, University of Wolverhampton, Wolverhampton WV1 1LY, UK.

Difficulty managing the demands of work and nonwork roles (often referred to in terms of managing balance) can be detrimental to psychological wellbeing and contribute to occupational burnout. The current study investigated the neural correlates of perceived satisfaction with this balance using both trait and state EEG alpha measures. EEG was recorded from 14 participants in full time employment (12 females, aged 35. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S09254927183027
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http://dx.doi.org/10.1016/j.pscychresns.2019.03.009DOI Listing
March 2019
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Duration of sick leave in patients with depression treated by general practitioners and psychiatrists.

Psychiatry Res 2019 Mar 26. Epub 2019 Mar 26.

Epidemiology, IQVIA, Unterschweinstiege 2-14, 60549, Frankfurt, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01651781193068
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http://dx.doi.org/10.1016/j.psychres.2019.03.045DOI Listing
March 2019
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Impaired prefrontal functional connectivity associated with working memory task performance and disorganization despite intact activations in schizophrenia.

Psychiatry Res Neuroimaging 2019 Mar 19;287:10-18. Epub 2019 Mar 19.

Palo Alto VA Healthcare System, 3801 Miranda Avenue, Palo Alto, CA 94304, USA; Stanford University, 401 Quarry Road, Palo Alto, CA 94301, USA. Electronic address:

Working memory (WM) deficits are key features of schizophrenia and are associated with significant functional impairment. The precise mechanisms of WM and their relationship between WM deficits with other clinical symptoms of schizophrenia remain unclear. Contemporary models propose that WM requires synchronous activity across brain regions within a distributed network, including lateral prefrontal cortex (PFC) and task-relevant posterior sensory cortical regions. Read More

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http://dx.doi.org/10.1016/j.pscychresns.2019.01.013DOI Listing
March 2019
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Mismatch negativity-indexed auditory change detection of speech sounds in early and chronic schizophrenia.

Psychiatry Res Neuroimaging 2019 Mar 20;287:1-9. Epub 2019 Mar 20.

Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada; Nova Scotia Early Psychosis Program, Nova Scotia Health Authority, Halifax, Nova Scotia, Canada.

Auditory change detection, as indexed by the EEG-derived mismatch negativity, has been demonstrated to be dysfunctional in chronic schizophrenia using both pure-tone and speech (phoneme) sounds. It is unclear, however, whether reduced MMN amplitudes to speech sound deviants are observed within the first 5 years of the illness. The present study investigated MMNs elicited by across-vowel (phoneme) change in early schizophrenia (ESZ; Experiment 1) as well as chronic schizophrenia (CSZ; Experiment 2). Read More

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http://dx.doi.org/10.1016/j.pscychresns.2019.03.010DOI Listing
March 2019
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Influence of earthquake exposure and left-behind status on severity of post-traumatic stress disorder and depression in Chinese adolescents.

Psychiatry Res 2019 Mar 19;275:253-260. Epub 2019 Mar 19.

Business school, Sichuan University, Chengdu 610064, PR China; Centre for Educational and Health Psychology, Sichuan University, Chengdu, PR China.

In the Longmenshan seismic fault zone in the Sichuan province of China, many children and adolescents have been exposed to the 2008 Wenchuan earthquake and/or the 2013 Lushan earthquake, and many are left alone for extended periods by parents who migrate to larger cities for work. We wished to examine how these two kinds of trauma-earthquake exposure and left-behind status-influence severity of post-traumatic stress disorder (PTSD) and depressive reactions. A cross-sectional survey of 2447 adolescents aged 13-18 at 11 schools in three cities in the Longmenshan fault zone was conducted in 2016. Read More

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http://dx.doi.org/10.1016/j.psychres.2019.01.109DOI Listing
March 2019
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Metabolic syndrome among older adults with schizophrenia spectrum disorder: Prevalence and associated factors in a multicenter study.

Psychiatry Res 2019 Mar 22;275:238-246. Epub 2019 Mar 22.

AP-HP, Western Paris University Hospitals, Department of Psychiatry, 92130 Issy-les-Moulineaux, France; INSERM UMR 894, Psychiatry and Neurosciences Center, Paris Descartes University, Sorbonne Paris Cité, Paris, France.

Metabolic syndrome and its associated morbidity and mortality have been well documented in adults with schizophrenia. However, data is lacking for their geriatric counterparts. We sought to investigate the frequency of screening and the prevalence of metabolic syndrome in older adults with schizophrenia, as well as its possible correlates, using the Cohort of individuals with schizophrenia Aged 55 years or more study (n = 353). Read More

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http://dx.doi.org/10.1016/j.psychres.2019.03.036DOI Listing
March 2019
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Do patients from the Democratic Republic of Congo with schizophrenia have facial emotion recognition deficits?

Psychiatry Res 2019 Mar 20;275:233-237. Epub 2019 Mar 20.

Clinique Notre-Dame des Anges, Institute of Neurosciences, IoNS, Université catholique de Louvain, 4000 Liège, Belgium. Electronic address:

Patients with schizophrenia can have difficulty recognizing emotion, and the impact of this difficulty on social functioning has been widely reported. However, earlier studies did not thoroughly explore how this deficit may vary according to emotion intensity, or how it may differ among individuals and across cultures. In the present study, our aim was to identify possible deficits in facial emotion recognition across a wide range of emotions of different intensities among patients with schizophrenia from the Democratic Republic of Congo (DRC). Read More

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http://dx.doi.org/10.1016/j.psychres.2019.03.030DOI Listing
March 2019
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Clinical outcomes and childhood trauma in bipolar disorder: A community sample of young adults.

Psychiatry Res 2018 Dec 21;275:228-232. Epub 2018 Dec 21.

Department of Health and Behavior, Catholic University of Pelotas, 373 Goncalves Chaves, 416C room, Zip code 96015-560, Pelotas, RS, Brazil. Electronic address:

Childhood trauma is a complex experience, much reported by subjects with bipolar disorder. There are still few studies that assess its consequences in a community sample of bipolar in early stage. The aim of the present study is to assess the association between childhood trauma and clinical outcomes, including the global functioning, in a community sample of young adults with bipolar disorder. Read More

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http://dx.doi.org/10.1016/j.psychres.2018.12.114DOI Listing
December 2018
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The stigma of mental illness: Testing for the implicit bias in diagnostic labels.

Psychiatry Res 2019 Mar 18;275:221-227. Epub 2019 Mar 18.

Universität Hamburg, Institute of Psychology, Clinical Psychology and Psychotherapy, Von-Melle-Park 5, 20146 Hamburg, Germany.

Several models that attempt to explain stigmatization of people with mental illness emphasize the relevance of social categorization. However, research on illness-based social categories has been limited to explicit self-report measures. In this study, we explored whether implicit social categorization based on mental illness labels can be assessed with the "Who-Said-What" (WSW)-paradigm. Read More

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http://dx.doi.org/10.1016/j.psychres.2019.03.028DOI Listing