743,366 results match your criteria Psychiatric services Washington D.C.[Journal]


Placental DNA methylation levels at CYP2E1 and IRS2 are associated with child outcome in a prospective autism study.

Hum Mol Genet 2019 Apr 22. Epub 2019 Apr 22.

Department of Medical Microbiology and Immunology, University of California, Davis, CA, USA.

DNA methylation acts at the interface of genetic and environmental factors relevant for autism spectrum disorder (ASD). Placenta, normally discarded at birth, is a potentially rich source of DNA methylation patterns predictive of ASD in the child. Here, we performed whole methylome analyses of placentas from a prospective study MARBLES (Markers of Autism Risk in Babies-Learning Early Signs) of high-risk pregnancies. Read More

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http://dx.doi.org/10.1093/hmg/ddz084DOI Listing

Long-Term Weight Loss With Metformin or Lifestyle Intervention in the Diabetes Prevention Program Outcomes Study.

Ann Intern Med 2019 Apr 23. Epub 2019 Apr 23.

Pennington Biomedical Research Center, Louisiana State University System, Baton Rouge, Louisiana (J.W.A., K.M.G.).

Background: Identifying reliable predictors of long-term weight loss (LTWL) could lead to improved weight management.

Objective: To identify some predictors of LTWL.

Design: The DPP (Diabetes Prevention Program) was a randomized controlled trial that compared weight loss with metformin, intensive lifestyle intervention (ILS), or placebo. Read More

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http://dx.doi.org/10.7326/M18-1605DOI Listing

The treatment gap for mental disorders and associated factors in the Czech Republic.

Eur Psychiatry 2019 Apr 19;59:37-43. Epub 2019 Apr 19.

National Institute of Mental Health, Klecany, Czech Republic; Third Faculty of Medicine, Charles University Prague, Czech Republic. Electronic address:

Objectives: To assess the extent of the treatment gap for mental disorders in the Czech Republic, determine factors associated with the utilization of mental health services and explore what influences willingness to seek mental health care.

Methods: Data from the CZEch Mental health Study, a nationally representative study of community-dwelling adults in the Czech Republic were used. The Mini International Neuropsychiatric Interview assessed the presence of mental disorders. Read More

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http://dx.doi.org/10.1016/j.eurpsy.2019.04.003DOI Listing

Differential associations of locus of control with anxiety, depression and life-events: A five-wave, nine-year study to test stability and change.

J Affect Disord 2019 Apr 11;253:26-34. Epub 2019 Apr 11.

University of Groningen, University Medical Center Groningen (UMCG), Department of Psychiatry, Interdisciplinary Center Psychopathology and Emotional regulation (ICPE), Groningen, the Netherlands.

Background: The locus of control (LOC) construct has been associated with onset, course, and severity of anxiety and depression. We investigated the stability of LOC, the bidirectional relationships between LOC and symptom severity of anxiety and depression over nine years, and the influence of intermediate positive and negative life-events on these associations.

Methods: Data came from five assessment waves over nine years of 2052 subjects with an anxiety or depressive disorder or healthy controls. Read More

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http://dx.doi.org/10.1016/j.jad.2019.04.005DOI Listing

Veterans with PTSD and comorbid substance use disorders: Does single versus poly-substance use disorder affect treatment outcomes?

Drug Alcohol Depend 2019 Apr 9;199:70-75. Epub 2019 Apr 9.

Department of Behavioral Sciences and Psychiatry, Division of Addiction Sciences, Medical University of South Carolina, 5 Charleston Center Dr., Suite 151, Charleston, SC, 29401 USA; Ralph H. Johnson VA Medical Center, 109 Bee St., Charleston, SC, 29401 USA.

Introduction: Substance use disorders (SUD) frequently co-occur with posttraumatic stress disorder (PTSD). Little is known, however, about how individuals with a single SUD diagnosis (relating to only one substance) compare to individuals with poly-SUD diagnoses (relating to more than one substance) on substance use and PTSD treatment outcomes. To address this gap in the literature, we utilized data from a larger study investigating a 12-week integrated, exposure-based treatment (i. Read More

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http://dx.doi.org/10.1016/j.drugalcdep.2019.04.001DOI Listing

Minimising the use of physical restraint in acute mental health services: The outcome of a restraint reduction programme ('REsTRAIN YOURSELF').

Int J Nurs Stud 2019 Mar 28;95:40-48. Epub 2019 Mar 28.

University of Liverpool, United Kingdom; Broset Centre for Research and Education in Forensic Psychiatry, Norway.

Background: Physical restraint is a coercive intervention used to prevent individuals from harming themselves or others. However, serious adverse effects have been reported. Minimising the use of restraint requires a multimodal approach to target both organisational and individual factors. Read More

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http://dx.doi.org/10.1016/j.ijnurstu.2019.03.016DOI Listing

The effect of frontoparietal paired associative stimulation on decision-making and working memory.

Cortex 2019 Mar 28;117:266-276. Epub 2019 Mar 28.

Department of Psychiatry, University of Cambridge, Cambridge, UK; Cambridgeshire and Peterborough NHS Foundation Trust, Cambridge, UK.

Previous single-site neurostimulation experiments have unsuccessfully attempted to shift decision-making away from habitual control, a fast, inflexible cognitive strategy, towards goal-directed control, a flexible, though computationally expensive strategy. We employed a dual-target neurostimulation approach in 30 healthy participants, using cortico-cortical paired associative stimulation (ccPAS) to target two key nodes: lateral prefrontal cortex (LPFC) and intraparietal sulcus (IPS), to test whether decision-making can be artificially shifted from habitual toward goal-directed control. Participants received three active stimulations, delivered at least six days apart (each involving 100 paired pulses over the IPS and LPFC, varying the interstimulus interval): two interventional, time-relevant ccPAS (10 msec interval) and one control, non-time-relevant ccPAS (100 msec interval). Read More

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http://dx.doi.org/10.1016/j.cortex.2019.03.015DOI Listing

Oxytocin Effects on Pain Perception and Pain Anticipation.

J Pain 2019 Apr 19. Epub 2019 Apr 19.

Department of General Psychiatry, University Hospital of Heidelberg, 69115 Heidelberg.

There is an ongoing debate whether the neuropeptide oxytocin (OT) modulates pain processing in humans. This study differentiates behavioral and neuronal OT effects on pain perception and pain anticipation by using a Pavlovian conditioning paradigm. Forty-six males received intranasally administered OT in a randomized double-blind, placebo-controlled group design. Read More

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http://dx.doi.org/10.1016/j.jpain.2019.04.002DOI Listing

Psychiatric Symptoms and Disorders in Extremely Preterm Young Adults at 19 Years of Age and Longitudinal Findings From Middle Childhood.

J Am Acad Child Adolesc Psychiatry 2019 Apr 19. Epub 2019 Apr 19.

Institute for Women's Health, University College London, UK.

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http://dx.doi.org/10.1016/j.jaac.2019.02.020DOI Listing

Validation of an Electronic Medical Record-Based Algorithm for Identifying Posttraumatic Stress Disorder in U.S. Veterans.

J Trauma Stress 2019 Apr;32(2):226-237

Massachusetts Veterans Epidemiology Research and Information Center (MAVERIC), VA Boston Healthcare System, Boston, Massachusetts, USA.

We developed an algorithm for identifying U.S. veterans with a history of posttraumatic stress disorder (PTSD), using the Department of Veterans Affairs (VA) electronic medical record (EMR) system. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1002/jts.22399
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http://dx.doi.org/10.1002/jts.22399DOI Listing
April 2019
1 Read

Gender-Stratified Prevalence of Psychiatric and Pain Diagnoses in a Primary Care Patient Sample with Fibromyalgia.

Pain Med 2019 Apr 22. Epub 2019 Apr 22.

Department of Family and Community Medicine, Saint Louis University School of Medicine, St. Louis, Missouri, USA.

Objective: Comorbid psychiatric and pain-related conditions are common in patients with fibromyalgia. Most studies in this area have used data from patients in specialty care and may not represent the characteristics of fibromyalgia in primary care patients. We sought to fill gaps in the literature by determining if the association between psychiatric diagnoses, conditions associated with chronic pain, and fibromyalgia differed by gender in a primary care patient population. Read More

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http://dx.doi.org/10.1093/pm/pnz084DOI Listing

Confidence boosts serial dependence in orientation estimation.

J Vis 2019 Apr;19(4):25

University of Wisconsin-Madison, Department of Psychology and Department of Psychiatry, Madison, WI.

In the absence of external feedback, a decision maker must rely on a subjective estimate of their decision accuracy in order to appropriately guide behavior. Normative models of perceptual decision-making relate subjective estimates of internal signal quality (e.g. Read More

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http://jov.arvojournals.org/article.aspx?doi=10.1167/19.4.25
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http://dx.doi.org/10.1167/19.4.25DOI Listing
April 2019
1 Read

Bifidobacterium longum R0175 attenuates post-myocardial infarction depressive-like behaviour in rats.

PLoS One 2019 22;14(4):e0215101. Epub 2019 Apr 22.

CIUSSS du Nord-de-l'Île-de-Montréal, Hôpital Sacré-Cœur, Montréal, Canada.

Caspase-3 activation in the limbic system and depressive-like symptoms are observed after an acute myocardial infarction (MI) and studies suggest that inflammation may play a significant role. Combined treatment with the probiotic strains Bifidobacterium longum and Lactobacillus helveticus in rats has been shown to attenuate caspase-3 activation and depressive-like behaviour together with a reduction in pro-inflammatory cytokines. The present study was designed to determine the respective contribution of these two strains on caspase-3 activity in the limbic system and on depressive-like behaviour. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0215101PLOS

Finding the balance between model complexity and performance: Using ventral striatal oscillations to classify feeding behavior in rats.

PLoS Comput Biol 2019 Apr 22;15(4):e1006838. Epub 2019 Apr 22.

Department of Psychiatry, Geisel School of Medicine at Dartmouth, Dartmouth College, Hanover, New Hampshire, United States of America.

The ventral striatum (VS) is a central node within a distributed network that controls appetitive behavior, and neuromodulation of the VS has demonstrated therapeutic potential for appetitive disorders. Local field potential (LFP) oscillations recorded from deep brain stimulation (DBS) electrodes within the VS are a pragmatic source of neural systems-level information about appetitive behavior that could be used in responsive neuromodulation systems. Here, we recorded LFPs from the bilateral nucleus accumbens core and shell (subregions of the VS) during limited access to palatable food across varying conditions of hunger and food palatability in male rats. Read More

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http://dx.doi.org/10.1371/journal.pcbi.1006838DOI Listing

Chronic pain is associated with a brain aging biomarker in community-dwelling older adults.

Pain 2019 May;160(5):1119-1130

Department of Neuroimaging, Centre for Neuroimaging Sciences, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom.

Chronic pain is associated with brain atrophy with limited evidence on its impact in the older adult's brain. We aimed to determine the associations between chronic pain and a brain aging biomarker in persons aged 60 to 83 years old. Participants of the Neuromodulatory Examination of Pain and Mobility Across the Lifespan (NEPAL) study (N = 47) completed demographic, psychological, and pain assessments followed by a quantitative sensory testing battery and a T1-weighted magnetic resonance imaging. Read More

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http://dx.doi.org/10.1097/j.pain.0000000000001491DOI Listing

Lesion Localization of Poststroke Lateropulsion.

Stroke 2019 May;50(5):1067-1073

Iowa Neuroimaging and Noninvasive Brain Stimulation Laboratory, Departments of Pediatrics, Neurology & Psychiatry, University of Iowa Hospitals and Clinics, Iowa City (F.M.A., A.D.B.).

Background and Purpose- Hemispheric stroke studies associating lateropulsion (pusher syndrome) with the location of brain lesions have had mixed results from small, unmatched samples. This study was designed to determine whether lateropulsion localizes to specific brain regions across patients with stroke using a case-control design. Methods- Fifty patients with lateropulsion after stroke were matched with 50 stroke patients without lateropulsion using age, time since onset of stroke, admission motor Functional Independence Measure score, lesion side, and gender. Read More

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http://dx.doi.org/10.1161/STROKEAHA.118.023445DOI Listing

A vocabulary describing health-terms of movement quality - a phenomenological study of movement communication.

Disabil Rehabil 2019 Apr 22:1-10. Epub 2019 Apr 22.

e Department of Journalism and Communication , University Carlos III of Madrid , Madrid , Spain.

Purpose: The aim of the study was to develop a vocabulary targeting communication of health-terms of movement quality, establishing professional knowledge of a movement terminology usefull within rehabilitation.

Methods: A phenomenological study design was chosen, inviting movement experts working in rehabilitation to describe movement observations when a change into more functional, health related ways of moving appeared in the rehabilitation processes. 15 physiotherapy experts were recruited, five from the field of neurology, primary health care and psychiatry. Read More

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https://www.tandfonline.com/doi/full/10.1080/09638288.2019.1
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http://dx.doi.org/10.1080/09638288.2019.1585970DOI Listing
April 2019
1 Read

Patient Satisfaction and Treatments Offered to Swedish Patients with Suspected Pediatric Acute-Onset Neuropsychiatric Syndrome and Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections.

J Child Adolesc Psychopharmacol 2019 Apr 19. Epub 2019 Apr 19.

1 Department of Clinical Neuroscience, Center for Psychiatry Research, Karolinska Institutet, Stockholm, Sweden.

Pediatric acute-onset neuropsychiatric syndrome (PANS) and pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections (PANDAS) are subtypes of Obsessive-Compulsive Disorder (OCD) with suggested autoimmune etiology. Immunomodulatory treatments have been introduced as treatment options. A recent systematic review concluded that the evidence for all treatment options for PANS and PANDAS is inconclusive. Read More

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http://dx.doi.org/10.1089/cap.2018.0141DOI Listing

Pharmacological Treatment of Youth Substance Use Disorders.

J Child Adolesc Psychopharmacol 2019 Apr 22. Epub 2019 Apr 22.

Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, South Carolina.

While the majority of youth who experiment with alcohol and drugs do not develop problematic levels of use, 5% of adolescents and 15% of young adults meet criteria for a substance use disorder (SUD). Pharmacotherapy, in combination with behavioral interventions, has the potential to increase the likelihood of successful treatment for youth struggling with SUD; however, the literature in this area is limited. To date, there are no Food and Drug Administration (FDA)-approved medications for adolescent SUD, other than buprenorphine, which has been approved down to 16 years of age for opioid use disorder. Read More

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http://dx.doi.org/10.1089/cap.2019.0009DOI Listing

Water Contaminant Levels Interact with Parenting Environment to Predict Development of Depressive Symptoms in Adolescents.

Dev Sci 2019 Apr 22:e12838. Epub 2019 Apr 22.

Ian H. Gotlib, Department of Psychology, Stanford University, 450 Serra Mall, Stanford, CA, 94305.

Contaminants in drinking water, such as lead, nitrate, and arsenic, have been linked to negative physical health outcomes. We know less, however, about whether such pollutants also predict mental health problems and, if so, the conditions under which such effects are strongest. In this longitudinal study, we examined whether drinking water contaminants interact with negative family environments (parental psychological control) to predict changes in depressive symptoms in 110 adolescents-a developmental period when symptoms often first emerge. Read More

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http://dx.doi.org/10.1111/desc.12838DOI Listing

Retinal vascular abnormalities in schizophrenia and bipolar disorder: A window to the brain.

Bipolar Disord 2019 Apr 22. Epub 2019 Apr 22.

Dept. of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore, India.

Objectives: The examination of retinal microvascular abnormalities through fundus photography is currently the best available non-invasive technique for assessment of cerebral vascular status. Several studies in the last decade have reported higher incidences of adverse cerebrovascular events in Schizophrenia (SCZ) and bipolar disorder (BD). However, retinal microvasculature abnormalities in SCZ and BD have remained under-explored, and no study has compared this aspect of SCZ and BD till date. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/bdi.12779
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http://dx.doi.org/10.1111/bdi.12779DOI Listing
April 2019
1 Read

N-Methyl-d-aspartate receptor open-channel blockers memantine and magnesium modulate nociceptive trigeminovascular neurotransmission in rats.

Eur J Neurosci 2019 Apr 22. Epub 2019 Apr 22.

Department of Neurology, University of California, San Francisco, San Francisco, CA, USA.

Experimental and clinical studies suggest that the low-affinity N-methyl-d-aspartate (NMDA) receptor open-channel blockers Mg and memantine are effective in reducing trigeminal nociceptive activation. The aim of the present study was to investigate the apparent effectiveness of these channel blockers using a model of trigeminal activation in vivo. Rats were anesthetized before electrically stimulating the dura mater adjacent the middle meningeal artery. Read More

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http://dx.doi.org/10.1111/ejn.14423DOI Listing

Multivariate analyses reveal biological components related to neuronal signaling and immunity mediating EEG abnormalities in alcohol-dependent individuals from the COGA cohort.

Alcohol Clin Exp Res 2019 Apr 22. Epub 2019 Apr 22.

Olin Neuropsychiatry Research Center, Hartford Hospital/IOL, Hartford, CT, 06107.

Background: The underlying molecular mechanisms associated with alcohol use disorder (AUD) risk have only been partially revealed using traditional approaches such as univariate GWAS and linkage-based analyses. We therefore aimed to identify gene clusters related to EEG neurobiological phenotypes distinctive to individuals with AUD using a multivariate approach.

Methods: The current project adopted a bi-multivariate data-driven approach, parallel independent component analysis (para-ICA) to derive and explore significant genotype-phenotype associations in a case-control subset of the Collaborative Study on the Genetics of Alcoholism (COGA) dataset. Read More

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http://dx.doi.org/10.1111/acer.14063DOI Listing

Biallelic MYORG mutation carriers exhibit primary brain calcification with a distinct phenotype.

Brain 2019 Apr 22. Epub 2019 Apr 22.

Normandie Univ, UNIROUEN, Inserm U1245 and Rouen University Hospital, Department of Genetics and CNR-MAJ, F 76000, Normandy Center for Genomic and Personalized Medicine, Rouen, France.

Primary familial brain calcification (PFBC) is a rare neurogenetic disorder with diverse neuropsychiatric expression. Mutations in four genes cause autosomal dominant PFBC: SLC20A2, XPR1, PDGFB and PDGFRB. Recently, biallelic mutations in the MYORG gene have been reported to cause PFBC with an autosomal recessive pattern of inheritance. Read More

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https://academic.oup.com/brain/advance-article/doi/10.1093/b
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http://dx.doi.org/10.1093/brain/awz095DOI Listing
April 2019
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Association Between Longitudinal Plasma Neurofilament Light and Neurodegeneration in Patients With Alzheimer Disease.

JAMA Neurol 2019 Apr 22. Epub 2019 Apr 22.

Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry, the Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.

Importance: Plasma neurofilament light (NfL) has been suggested as a noninvasive biomarker to monitor neurodegeneration in Alzheimer disease (AD), but studies are lacking.

Objective: To examine whether longitudinal plasma NfL levels are associated with other hallmarks of AD.

Design, Setting, And Participants: This North American cohort study used data from 1583 individuals in the multicenter Alzheimer's Disease Neuroimaging Initiative study from September 7, 2005, through June 16, 2016. Read More

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http://dx.doi.org/10.1001/jamaneurol.2019.0765DOI Listing

Association of Cumulative Socioeconomic and Health-Related Disadvantage With Disparities in Smoking Prevalence in the United States, 2008 to 2017.

JAMA Intern Med 2019 Apr 22. Epub 2019 Apr 22.

Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles.

Importance: Understanding emerging patterns of smoking disparities among disadvantaged populations can guide tobacco control policy.

Objective: To estimate disparities in smoking prevalence associated with the number of socioeconomic and health-related disadvantages faced by a population among US adults from 2008 to 2017.

Design, Setting, And Participants: Nationally representative cross-sectional annual household-based probability sample of US noninstitutionalized residents. Read More

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http://dx.doi.org/10.1001/jamainternmed.2019.0192DOI Listing

Depression involved in self-reported prospective memory problems in survivors of breast cancer who have received chemotherapy.

Medicine (Baltimore) 2019 Apr;98(16):e15301

Department of Oncology, The Second Affiliated Hospital of Anhui Medical University.

To investigate the relationship between depression and the self-reported prospective memory (SPM) problems in breast cancer survivors who have received chemotherapy.Sixty-three breast cancer patients were administered with self-rating depression scale (SDS) and the prospective memory questionnaire as part of extensive neuropsychological assessments before and after chemotherapy. The performance of SDS and SPM were compared, with the level of significance set at P < . Read More

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http://dx.doi.org/10.1097/MD.0000000000015301DOI Listing

High-Functioning Autism, Severe Anxiety, and Bullying in a 26 Year Old.

J Dev Behav Pediatr 2019 Apr 16. Epub 2019 Apr 16.

Research Institute in Developmental Medicine, Johannes Kepler University, Linz, Austria.

Case: Peter is a 26-year-old group home resident in Austria with a history of poor peer relationships, including being bullied, and previous diagnoses of attention-deficit hyperactivity disorder, Asperger syndrome, social anxiety, depression, and developmental coordination disorder. Consultation from our international neurodevelopmental team was requested for severe anxiety and avoidance of social interactions. He reported 4 or more spontaneous anxiety episodes per day. Read More

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http://dx.doi.org/10.1097/DBP.0000000000000674DOI Listing

Altered neuropsychological performance and reduced brain volumetrics in people living with HIV on integrase strand transfer inhibitors.

AIDS 2019 Apr 16. Epub 2019 Apr 16.

Department of Neurology, Washington University in St Louis, St Louis, USA.

Objectives: Neuropsychiatric symptoms have been reported in people living with HIV (PLWH) on integrase strand transfer inhibitors (INSTIs) in post marketing analysis. Limited data exists regarding brain integrity (function and structure) in PLWH prescribed INSTIs compared to other HIV treatment regimens.

Design: A cross-sectional analysis of PLWH on combined antiretroviral therapy (cART) aged >18 years at a single institution. Read More

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http://dx.doi.org/10.1097/QAD.0000000000002236DOI Listing

Diagnosis and treatment of patients with comorbid substance use disorder and adult attention-deficit and hyperactivity disorder: a review of recent publications.

Curr Opin Psychiatry 2019 Apr 16. Epub 2019 Apr 16.

Amsterdam Institute of Addiction Research (AIAR), Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands.

Purpose Of Review: Attention-deficit and hyperactivity disorder (ADHD) often presents with comorbid substance use disorders (SUD). Due to similarities in key symptoms of both disorders and suboptimal efficacy of the available treatments, clinicians are faced with difficulties in the diagnosis and treatment of these patients with both disorders. This review addresses recent publications between 2017 and 2019 on the etiology, prevalence, diagnosis and treatment of co-occurring ADHD and SUD. Read More

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http://dx.doi.org/10.1097/YCO.0000000000000513DOI Listing

Self-directed interventions for gambling disorder.

Curr Opin Psychiatry 2019 Apr 16. Epub 2019 Apr 16.

Faculty of Health and Environmental Sciences, National Institute for Public Health and Mental Health Research, Auckland University of Technology, Northcote, Auckland, New Zealand.

Purpose Of Review: To assess recent developments in self-directed interventions for gambling disorder and at-risk gambling.

Recent Findings: Relevant reviews and meta-analyses were published during 2017 and 2018. These reviews assess the nature and efficacy of self-directed and largely self-directed interventions including self-change, assisted self-change and mutual aid support groups. Read More

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http://dx.doi.org/10.1097/YCO.0000000000000515DOI Listing

Medications to treat cocaine use disorders: current options.

Curr Opin Psychiatry 2019 Apr 16. Epub 2019 Apr 16.

Addiction Psychiatry Residency Program, Department of Psychiatry & Behavioral Sciences, University of Washington School of Medicine, Director, Center of Excellence in Substance Abuse Treatment and Education (CESATE), VA Puget Sound Healthcare System, Seattle, Washington, USA.

Purpose Of Review: Cocaine is a highly addictive substance with serious medical and mental health consequences. Despite these concerns, there are no food and drug administration-approved medications for the treatment of cocaine use disorder (CUD). Although many medication-assisted treatments (MATs) have been investigated, no clear guidelines exist for clinicians treating patients with CUDs. Read More

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http://dx.doi.org/10.1097/YCO.0000000000000518DOI Listing

Human prion diseases.

Curr Opin Infect Dis 2019 Apr 16. Epub 2019 Apr 16.

Department of Neurology, University Hospitals Cleveland Medical Center.

Purpose Of Review: Prion diseases are rapidly progressive neurodegenerative conditions that can be difficult to diagnose and are transmissible under specific circumstances. The authors will provide background regarding prion disease and focus on diagnostic tools.

Recent Findings: Prion disease is caused by misfolded prion protein. Read More

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http://dx.doi.org/10.1097/QCO.0000000000000552DOI Listing

Mental Health Apps in Psychiatric Treatment: A Patient Perspective on Real World Technology Usage.

JMIR Ment Health 2019 Apr 22;6(4):e12292. Epub 2019 Apr 22.

Wistia, Cambridge, MA, United States.

For many people who use mobile apps, the primary motivations are entertainment, news, gaming, social connections, or productivity. For those experiencing health problems, particularly those with chronic conditions such as psychiatric disorders, the stakes are much higher. The digital tools that they select may be the difference between improvement and decompensation or even life and death. Read More

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http://dx.doi.org/10.2196/12292DOI Listing

Introduction of Veronica Decker, Guest Editor of Special Issue on Technology in Psychiatric-Mental Health Clinical Practice, Research, and Education.

Authors:
Sandra P Thomas

Issues Ment Health Nurs 2019 Mar;40(3):199

a University of Tennessee, Knoxville, Knoxville, Tennessee, USA.

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http://dx.doi.org/10.1080/01612840.2019.1548848DOI Listing

Preventive cognitive therapy versus care as usual in cognitive behavioral therapy responders: A randomized controlled trial.

J Consult Clin Psychol 2019 Apr 22. Epub 2019 Apr 22.

Department of Research, Arkin.

Objective: The optimization of long-term outcomes is an important goal in the treatment of major depressive disorder. Offering subsequent preventive cognitive therapy (PCT) to patients who responded to acute cognitive behavioral therapy (CBT) may reduce the risk of relapse/recurrence.

Method: Therefore, a multicenter randomized controlled trial was conducted comparing the addition of eight weekly sessions of PCT to care as usual (CAU) versus CAU alone in patients with a history of depression in remission following treatment with CBT. Read More

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http://dx.doi.org/10.1037/ccp0000395DOI Listing

Examining race as a predictor and moderator of treatment outcomes for binge-eating disorder: Analysis of aggregated randomized controlled trials.

J Consult Clin Psychol 2019 Apr 22. Epub 2019 Apr 22.

Department of Psychiatry, School of Medicine, Yale University.

Objective: To examine whether race predicted or moderated response to treatments for binge-eating disorder (BED).

Method: Participants were 592 adults (n = 113 Black; n = 479 White) with DSM-IV-defined BED who participated in randomized controlled trials (RCTs) at 1 medical center. Data were aggregated from RCTs for BED testing cognitive-behavioral therapy, behavioral weight loss, multimodal treatment, and/or control conditions. Read More

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http://dx.doi.org/10.1037/ccp0000404DOI Listing

Efficacy and mediators of a group cognitive-behavioral therapy for hoarding disorder: A randomized trial.

J Consult Clin Psychol 2019 Apr 22. Epub 2019 Apr 22.

Institute of Living.

Objective: Hoarding disorder (HD) is a common and potentially debilitating psychiatric disorder. Thus far, psychological treatments have yielded modest effects and/or were time-consuming and costly to deliver. The aim of the present study was to test the efficacy of a brief group cognitive-behavioral therapy (CBT) for adults with HD and to test hypothesized mediators of treatment outcome. Read More

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http://dx.doi.org/10.1037/ccp0000405DOI Listing

Estimating outcome probabilities from early symptom changes in cognitive therapy for recurrent depression.

J Consult Clin Psychol 2019 Apr 22. Epub 2019 Apr 22.

Department of Psychiatry, The University of Texas Southwestern Medical Center.

Objective: Acute-phase cognitive therapy (CT) is an efficacious treatment for major depressive disorder (MDD) producing benefits comparable to pharmacotherapy, but not all patients respond or remit. The purpose of the current analyses was to estimate CT patients' probability of nonresponse and remission from symptom improvement early in treatment.

Method: Data from 2 clinical trials of acute-phase CT for recurrent depression were pooled for analysis (N = 679). Read More

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http://dx.doi.org/10.1037/ccp0000409DOI Listing

Trends in substance use and in the attributable burden of disease and mortality in the WHO European Region, 2010-16.

Eur J Public Health 2019 Apr 22. Epub 2019 Apr 22.

WHO European Office for Prevention and Control of Noncommunicable Diseases, World Health Organization, Regional Office for Europe, Moscow, Russian Federation.

Background: This paper examines changes in substance use, and compares the resulting attributable burden of disease in the WHO European Region between 2010 and 2016.

Methods: Data for 2010 and 2016 on the number of deaths, years of life lost (YLL) and disability-adjusted life years (DALYs) lost were obtained by sex and country from the 2016 Global Burden of Disease (GBD) study. Exposure data for all substances except alcohol were obtained from the same study, while alcohol data were obtained from the WHO. Read More

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http://dx.doi.org/10.1093/eurpub/ckz064DOI Listing

Trends across 20 years in multiple indicators of functioning among older adults in the Netherlands.

Eur J Public Health 2019 Apr 22. Epub 2019 Apr 22.

Department of Epidemiology and Biostatistics, Amsterdam Public Health Research Institute, Amsterdam UMC - Location VU University Medical Center, Amsterdam, The Netherlands.

Background: Monitoring of trends in functioning of older adults provides indispensable information for health care policy. This study examined trends in multiple indicators of functioning among Dutch older adults across a period of 20 years.

Methods: Data from the Longitudinal Aging Study Amsterdam were used. Read More

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https://academic.oup.com/eurpub/advance-article/doi/10.1093/
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http://dx.doi.org/10.1093/eurpub/ckz065DOI Listing
April 2019
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Lack of Association Between Serotonin Transporter Gene (SLC6A4) Promoter Methylation and Amygdala Response During Negative Emotion Processing in Individuals With Alcohol Dependence.

Alcohol Alcohol 2019 Apr 22. Epub 2019 Apr 22.

Section on Clinical Genomics and Experimental Therapeutics, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, 10 Center Drive (10CRC), Bethesda, MD 20892, USA.

Aims: Differences in DNA methylation of the serotonin transporter gene (SLC6A4) have been shown to alter SLC6A4 expression and predict brain functions in healthy individuals. This study investigated the association between SLC6A4 promoter methylation and threat-related amygdala activation in individuals with alcohol dependence (AD).

Methods: Methylation of the SLC6A4 promoter region was assessed using peripheral blood DNA from 45 individuals with AD and 45 healthy controls (HCs). Read More

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http://dx.doi.org/10.1093/alcalc/agz032DOI Listing

Letter to Editor. Thromboembolic complications in psychiatry from the perspective of legal claims.

Psychiatr Pol 2019 Feb 28;53(1):209-211. Epub 2019 Feb 28.

Oddział Kliniczny Chorób Wewnętrznych i Chemioterapii Onkologicznej Samodzielnego Publicznego Szpitala Klinicznego im. Andrzeja Mielęckiego w Katowicach.

no summary. Read More

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http://psychiatriapolska.pl/209___.html
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http://dx.doi.org/10.12740/PP/99145DOI Listing
February 2019
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An open letter to the Readers of "Polish Psychiatry".

Psychiatr Pol 2019 Feb 28;53(1):203-207. Epub 2019 Feb 28.

Instytut Psychiatrii i Neurologii, Klinika Psychiatrii Sądowej.

no summary. Read More

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http://www.psychiatriapolska.pl/203___.html
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http://dx.doi.org/10.12740/PP/104715DOI Listing
February 2019
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Fear of imminent death - use of evidence in forensic-psychiatric expertise.

Psychiatr Pol 2019 Feb 28;53(1):191-201. Epub 2019 Feb 28.

Instytut Psychologii, Wydział Filozofii Chrześcijańskiej, Uniwersytet Kardynała Stefana Wyszyńskiego w Warszawie.

In accordance with the Polish civil law, there are at least several ways to dispose of property in the event of death. One of them is a special form of oral testament. The main issue to be determined by the court is to either confirm or deny the existence of fear of imminent death of the testator at the time of bequest. Read More

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http://dx.doi.org/10.12740/PP/OnlineFirst/84797DOI Listing
February 2019

Hoarding disorder and cerebellum damage. A case study.

Psychiatr Pol 2019 Feb 28;53(1):161-166. Epub 2019 Feb 28.

Warszawski Uniwersytet Medyczny, Katedra i Klinika Psychiatryczna.

Hoarding disorder is defined as an extensive collecting and difficulty in discarding objects and items perceived by others as not useful or having low value. As a consequence it leads to numerous problems which impact not only the patient but also his/her family and other people (e.g. Read More

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http://dx.doi.org/10.12740/PP/89994DOI Listing
February 2019

Sense and need for power in schizophrenic patients.

Psychiatr Pol 2019 Feb 28;53(1):105-115. Epub 2019 Feb 28.

Niepubliczny Zakład Opieki Zdrowotnej ALTERMED w Katowicach.

Objectives: The purpose of the research was to analyze the sense of power of schizophrenic patients in relations with others, physicians, their need for power and influence as well as the sense of being able to have power and influence. Dependencies linked with the age and gender were also analyzed by comparing the study group and the control group.

Methods: The study group included 47 patients diagnosed with F20 (Schizophrenia). Read More

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http://dx.doi.org/10.12740/PP/80146DOI Listing
February 2019
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