1,354 results match your criteria Psoriatic Arthritis Imaging


Clinical Characteristics of Patients with Spondyloarthritis in Japan in Comparison with Other Regions of the World.

J Rheumatol 2019 Feb 15. Epub 2019 Feb 15.

From the Immuno-Rheumatology Center, St. Luke's International Hospital, St. Luke's International University; Institute of Rheumatology, Tokyo Women's Medical University; Department of Orthopedic Surgery, Juntendo University School of Medicine; Division of Rheumatology, Department of Rheumatology, Keio University School of Medicine, Tokyo; Department of Orthopedic Surgery, Shiga University of Medical Science, Shiga; Department of Rheumatology, Tonan Hospital, Hokkaido; Department of Orthopedic Surgery, Fujita Health University, Aichi; Department of Internal Medicine and Rheumatology, Juntendo University School of Medicine, Tokyo; Department of Rheumatology, Chubu Rosai Hospital, Aichi; Department of Endocrinology, Metabolism and Nephrology, Kochi Medical School, Kochi; Department of Orthopedics, Osaka Minami Medical Center, Osaka; Department of Rheumatology, Daido Hospital, Aichi; Department of Internal Medicine, Juntendo University Koshigaya Hospital, Saitama; Department of Orthopedic Biomaterial Science, Osaka University Graduate School of Medicine, Osaka, Japan; departments of Epidemiology and Biostatistics, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA; Division of Rheumatology, National University Hospital, Singapore; Division of Rheumatology, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China; Department of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea; Department of Rheumatology, Allergy and Immunology, Chang Gung Memorial Hospital and Chang Gung University, Tao-Yuan, Taiwan; Hospital Universitario Reina Sofía/IMIBIC/University of Córdoba, Córdoba, Spain; Department of Rheumatology, Paris Descartes University, Cochin Hospital, Paris, France; INSERM Unit 1183, CRESS, Paris, France; Department of Rheumatology, Leiden University Medical Center, Leiden, the Netherlands. This study was conducted under the umbrella of the International Society for Spondyloarthritis Assessment (ASAS) and the COMOSPA study was supported by the unrestricted grants from Pfizer, AbbVie, and UCB. M.K. received honoraria from AbbVie and Ayumi; K.Y. receives tuition support from Harvard T.H. Chan School of Public Health (partially supported by training grants from Pfizer, Takeda, Bayer, and PhRMA); A.M. has received research grants from Abbvie, Pfizer, and MSD. M. Kishimoto, MD, Immuno-Rheumatology Center, St. Luke's International Hospital, St. Luke's International University; K. Yoshida, MD, MPH, ScD, Departments of Epidemiology and Biostatistics, Harvard T.H. Chan School of Public Health; N. Ichikawa, MD, Institute of Rheumatology, Tokyo Women's Medical University; H. Inoue, MD, Department of Orthopedic Surgery, Juntendo University School of Medicine; Y. Kaneko, MD, Division of Rheumatology, Department of Rheumatology, Keio University School of Medicine; T. Kawasaki, MD, Department of Orthopedic Surgery, Shiga University of Medical Science; K. Matsui, MD, Department of Rheumatology, Tonan Hospital, M. Morita, MD, Department of Orthopedic Surgery, Fujita Health University; M. Suda, MD, Immuno-Rheumatology Center, St. Luke's International Hospital, St. Luke's International University; K. Tada, MD, Department of Internal Medicine and Rheumatology, Juntendo University School of Medicine; N. Takizawa, MD, Department of Rheumatology, Chubu Rosai Hospital; N. Tamura, MD, Department of Internal Medicine and Rheumatology, Juntendo University School of Medicine; A. Taniguchi, MD, Institute of Rheumatology, Tokyo Women's Medical University; Y. Taniguchi, MD, Department of Endocrinology, Metabolism and Nephrology, Kochi Medical School; S. Tsuji, MD, Department of Orthopedics, Osaka Minami Medical Center; Y. Haji, MD, Department of Rheumatology, Daido Hospital; R. Rokutanda, MD, Immuno-Rheumatology Center, St. Luke's International Hospital, St. Luke's International University; H. Yanaoka, MD, Immuno-Rheumatology Center, St. Luke's International Hospital, St. Luke's International University; P.P. Cheung, MD, Division of Rheumatology, National University Hospital; J. Gu, MD, Division of Rheumatology, The Third Affiliated Hospital of Sun Yat-sen University; T.H. Kim, MD, Department of Rheumatology, Hanyang University Hospital for Rheumatic Diseases; S.F. Luo, MD, Department of Rheumatology, Allergy and Immunology, Chang Gung Memorial Hospital and Chang Gung University; M. Okada, MD, Immuno-Rheumatology Center, St. Luke's International Hospital, St. Luke's International University; C. López Medina, MD, Hospital Universitario Reina Sofía/IMIBIC/University of Córdoba; A. Molto, MD, Department of Rheumatology, Paris Descartes University, Cochin Hospital, and INSERM Unit 1183, CRESS; M. Dougados, MD, Department of Rheumatology, Paris Descartes University, Cochin Hospital, and INSERM Unit 1183, CRESS; S. Kobayashi, MD, PhD, Department of Internal Medicine, Juntendo University Koshigaya Hospital; D. van der Heijde, MD, Department of Rheumatology, Leiden University Medical Center; T. Tomita, MD, Department of Orthopedic Biomaterial Science, Osaka University Graduate School of Medicine. Address correspondence to Dr. M. Kishimoto, Immuno-Rheumatology Center, St. Luke's International Hospital, St. Luke's International University, 9-1 Akashicho, Chuo-ku, Tokyo, Japan, 104-8560. E-mail: Accepted for publication October 11, 2018.

Objective: To delineate clinical characteristics of patients with spondyloarthritis (SpA) in Japan in comparison to other areas of the world.

Methods: Using the ASAS-COMOSPA (Assessment of Spondyloarthritis international Society-COMOrbidities in SPondyloArthritis) data, an international cross-sectional observational study of patients with SpA, we analyzed information on demographics, disease characteristics, comorbidities, and risk factors. Patients were classified by region: Japan, other Asian countries (China, Singapore, South Korea, Taiwan), and non-Asian countries (Europe, the Americas, Africa). Read More

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http://dx.doi.org/10.3899/jrheum.180412DOI Listing
February 2019
1 Read

Radiographic scoring methods in rheumatoid arthritis and psoriatic arthritis.

Radiol Med 2019 Feb 9. Epub 2019 Feb 9.

Radiology Department, Università Politecnica delle Marche, Ancona, Italy.

Structural changes of bone and cartilage are the hallmarks of rheumatoid arthritis (RA) and psoriatic arthritis (PsA). Radiography can help in making diagnosis and in differentiating PsA and RA from other articular diseases. Radiography is still considered the preferred imaging method to assess disease progression, reflecting cumulative damage over time. Read More

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http://dx.doi.org/10.1007/s11547-019-01001-3DOI Listing
February 2019
5 Reads

The OMERACT MRI in Enthesitis Initiative: Definitions of Key Pathologies, Suggested MRI Sequences and Novel Heel Enthesitis Scoring System (HEMRIS).

J Rheumatol 2019 Feb 1. Epub 2019 Feb 1.

Department of Clinical Immunology & Rheumatology, Christian Medical College, Vellore, India; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Glostrup, Denmark; Department of Diagnostic Imaging, Sheba Medical Center, Affiliated to the Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel; Hôpitaux Universitaires Pitié Salpêtrière, Paris, France; Paris 6 University, GRC-UPMC 08, Pierre Louis Institute of Epidemiology and Public Health, Paris, France; Division of Medicine, University of New South Wales, Sydney, Australia; Cliniques Universitaires Saint-Luc, Institut de Recherche Expérimentale et Clinique (IREC), Université catholique de Louvain, Brussels, Belgium; Department of Radiology and Diagnostic Imaging, University of Alberta, Edmonton, Canada; Department of Radiology, Arthritis Imaging Research Group, University Hospital Charité, Berlin, Germany; CaRE (Canadian Research Education) Arthritis and Department of Medicine, University of Alberta, Edmonton, Canada; Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway; CaRE (Canadian Research Education) Arthritis, Edmonton, Canada; Service de Radiologie, Hôpital Lariboisiére, APHP & Université Paris-Diderot, Paris, France; Department of Rheumatology, Ghent University Hospital, Ghent, Belgium; Faculty of Medicine and Health, University of Leeds, United Kingdom. Address correspondence to Mikkel Østergaard, MD, PhD, DMSc, COPECARE - Center for Rheumatology and Spine Diseases, Rigshospitalet, Nordre Ringvej 57, DK-2600 Glostrup, Denmark Email:

Objective: To develop and validate an enthesitis MRI-scoring system for spondyloarthritis/psoriatic arthritis, using the heel as model.

Methods: Consensus definitions of key pathologies and three heel enthesitis multi-reader scoring exercises were done, separated by discussion, training and calibration.

Results: Definitions for bone and soft tissue pathologies were agreed. Read More

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http://dx.doi.org/10.3899/jrheum.181093DOI Listing
February 2019
1 Read

The "green nail" phenomenon in ICG-enhanced fluorescence optical imaging - a potential tool for the differential diagnosis of psoriatic arthritis.

J Dtsch Dermatol Ges 2019 Feb 31;17(2):138-147. Epub 2019 Jan 31.

Department of Dermatology and Allergology, Evangelical Hospital, Düsseldorf, and Faculty of Health, Department of Medicine, University of Witten/Herdecke, Germany.

Background And Objectives: Early diagnosis of psoriatic arthritis poses a particular challenge. A novel fluorescence optical imaging technique, the Xiralite® system is very useful in this regard as it allows for visualization of microvasculature and perfusion. The present study is the first to systematically examine fluorescence optical signals in a large psoriatic arthritis cohort. Read More

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http://dx.doi.org/10.1111/ddg.13747DOI Listing
February 2019
1 Read

Incidence rates of inflammatory bowel disease in patients with psoriasis, psoriatic arthritis and ankylosing spondylitis treated with secukinumab: a retrospective analysis of pooled data from 21 clinical trials.

Ann Rheum Dis 2019 Jan 23. Epub 2019 Jan 23.

Novartis Pharma AG, Basel, Switzerland.

Objectives: Here, we present the reported incidence rates of inflammatory bowel disease (IBD) in patients receiving treatment with secukinumab for psoriasis (PsO), psoriatic arthritis (PsA) or ankylosing spondylitis (AS), in a pooled analysis of 21 clinical trials.

Methods: Data from all patients who had received at least one dose of secukinumab were included. Safety analyses were conducted to evaluate cumulative IBD rates as well as per-year rates, by indication. Read More

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http://dx.doi.org/10.1136/annrheumdis-2018-214273DOI Listing
January 2019
8 Reads

The ultrasonographic study of the nail reveals differences in patients affected by inflammatory and degenerative conditions.

Clin Rheumatol 2019 Jan 15. Epub 2019 Jan 15.

Rheumatology Unit, Department of Medicine, University of Verona, Piazzale A. L. Scuro 1, 37138, Verona, Italy.

Introduction And Objectives: The nail unit is a subject of interest in several diseases, often involving different medical fields. Even if few data are available for psoriasis and psoriatic arthritis, no data regarding ultrasonography and imaging are present for other degenerative and inflammatory conditions. The aim of this study was to explore through imaging the changes of nail and enthesis in inflammatory and degenerative conditions in order to find qualitative and quantitative changes related to distal interphalangeal joints. Read More

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http://link.springer.com/10.1007/s10067-019-04437-0
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http://dx.doi.org/10.1007/s10067-019-04437-0DOI Listing
January 2019
5 Reads

Psoriatic fasciitis in a pediatric patient: A case report.

World J Clin Cases 2019 Jan;7(1):69-72

Department of Pediatric Rheumatology, Pamukkale University School of Medicine, Denizli 20070, Turkey.

Background: Diffuse fasciitis with psoriatic arthritis on magnetic resonance imaging (MRI) has not been previously described in childhood. Here we present the first case report of a pediatric patient developing fasciitis, beyond plantar fasciitis, with psoriatic arthritis.

Case Summary: An 11-year-old female was admitted with the complaints of psoriatic rash on the body associated with severe pain in the lower extremities and arthritis in the right knee. Read More

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http://dx.doi.org/10.12998/wjcc.v7.i1.69DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327131PMC
January 2019
2 Reads

Skin inflammation associated with arthritis, synovitis and enthesitis. Part 1: psoriatic arthritis, SAPHO syndrome, Still's disease, Behçet's disease.

J Dtsch Dermatol Ges 2019 Jan;17(1):43-64

Department of Rheumatology and Clinical Immunology, Freiburg University Medical Center, Medical Faculty of the Albert Ludwigs University, Freiburg, Germany.

The coincidence of skin and joint inflammation poses a challenge for both dermatologists and rheumatologists. Adequate management of such disorders requires that physicians of both specialties have sound knowledge of the other discipline. In case of suspected joint involvement, familiarity with the diagnostic options available to rheumatologists enables dermatologists to selectively refer their patients for a rheumatology consult. Read More

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http://dx.doi.org/10.1111/ddg.13742DOI Listing
January 2019
2 Reads

Pathophysiology, assessment and treatment of psoriatic dactylitis.

Nat Rev Rheumatol 2019 Feb;15(2):113-122

Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK.

Dactylitis is diffuse swelling of the digits that is usually related to an underlying inflammatory or infiltrative disorder. Psoriatic arthritis (PsA) is the most common severe disease thought to cause dactylitis. Our understanding of the pathogenesis of PsA-related dactylitis comes from experimental animal models of PsA-like disease, as well as advances in imaging and other clinical studies. Read More

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http://dx.doi.org/10.1038/s41584-018-0147-9DOI Listing
February 2019
2 Reads

HIV-associated psoriasis: Epidemiology, pathogenesis, and management.

Dermatol Ther 2018 Dec 27:e12806. Epub 2018 Dec 27.

Department of Biomedical and Dental Sciences and Morpho Functional Imaging, University of Messina, Messina, Italy.

People living with HIV (PLWH) are affected by a higher incidence skin disorders, which are often associated with high morbidity and mortality. In particular, psoriasis affects PLWH severely and for a longer time than the general population. Human immunodeficiency virus (HIV) infection is characterized by a progressive decrease in CD4 T-cell count, and it could seem paradoxical that psoriasis exacerbations are more frequent in this subset of patients than the general population, even though it is commonly observed at any stage of infection. Read More

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http://doi.wiley.com/10.1111/dth.12806
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http://dx.doi.org/10.1111/dth.12806DOI Listing
December 2018
9 Reads

Thermal alterations in patients with inflammatory diseases: a comparison between psoriatic and rheumatoid arthritis.

Reumatismo 2018 Dec 20;70(4):225-231. Epub 2018 Dec 20.

Department of Medicine and Aging Science, Dermatologic Clinic, University G. d'Annunzio, Chieti.

Functional infrared imaging (fIRI) is used to provide information on circulation, thermal properties and thermoregulatory function of the cutaneous tissue in several clinical settings. This study aims to evaluate the application of fIRI in rheumatoid arthritis (RA) assessment, evaluating the thermoregulatory alterations due to joint inflammation in RA patients both in basal conditions and after a mild functional (isometric) exercise, using the same protocol we projected in our recent work on psoriatic arthritis (PsA); fIRI outcomes were compared with those provided by power-Doppler ultrasonography. Ten patients with RA and 11 healthy controls were enrolled in the study. Read More

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http://dx.doi.org/10.4081/reumatismo.2018.1050DOI Listing
December 2018
1 Read

Preliminary validation of the Simplified Psoriatic Arthritis Radiographic Score (SPARS).

Skeletal Radiol 2018 Dec 7. Epub 2018 Dec 7.

Radiology Department, Università Politecnica delle Marche, Ancona, Italy.

Objective: To develop and validate in a preliminary way a novel radiographic scoring system for psoriatic arthritis (PsA), called Simplified Psoriatic Arthritis Radiographic Score (SPARS).

Materials And Methods: Radiographs of hands and feet were obtained from consecutive PsA patients and assessed by two readers. For each joint (30 joints in the hands, ten joints in the feet), the combination of the erosions, joint narrowing space (JNS) and bony proliferation (BP) has been assessed, giving a value of 1 for erosions presence, 1 for JNS presence, and 1 for BP presence (SPARS score range, 0-120). Read More

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http://link.springer.com/10.1007/s00256-018-3124-0
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http://dx.doi.org/10.1007/s00256-018-3124-0DOI Listing
December 2018
14 Reads

Update on the epidemiology, risk factors, and disease outcomes of psoriatic arthritis.

Best Pract Res Clin Rheumatol 2018 04 5;32(2):295-311. Epub 2018 Oct 5.

Division of Rheumatology, University of Ottawa, 1967 Riverside Drive, Ottawa, ON, K1H 7W9, Canada; The Ottawa Hospital Research Institute, University of Ottawa, 1967 Riverside Drive, Ottawa, ON, K1H 7W9, Canada. Electronic address:

Psoriatic arthritis (PsA) is a chronic inflammatory disease that affects different structures of the musculoskeletal system in addition to the skin and the nail. The complexity of the disease had been a barrier to understand the pathogenesis and define valid outcome tools; however, our understanding about the disease has considerably increased with time mainly because of the advances in imaging, new discoveries in genetics and underlying inflammatory pathways, and better understanding of the epidemiology of the disease and environmental risk factors. The purpose of this review is to summarize developments and changes in epidemiology, risk factors for developing PsA, and outcome measures with a focus on data obtained in the last 10 years. Read More

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http://dx.doi.org/10.1016/j.berh.2018.09.006DOI Listing
April 2018
4 Reads

Imaging in rheumatoid arthritis, psoriatic arthritis, axial spondyloarthritis, and osteoarthritis: An international viewpoint on the current knowledge and future research priorities.

Eur J Rheumatol 2018 Nov 16:1-10. Epub 2018 Nov 16.

Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK.

Imaging is increasingly used in the routine management of rheumatic diseases as well as in the clinical trials of these disorders. This viewpoint, authored by a group of international imaging experts following two meetings dedicated to imaging in rheumatology, reports a consensus about the current knowledge and addresses where further research should be focused based on the views of the international imaging experts and discussion of the evidence with attending imaging practitioners. The goal was to maximize the potential of imaging to improve the clinical management of four rheumatic diseases. Read More

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http://dx.doi.org/10.5152/eurjrheum.2018.18121DOI Listing
November 2018
3 Reads

Classifications and imaging of juvenile spondyloarthritis.

J Ultrason 2018 ;18(74):224-233

University of Nis, Faculty of Medicine, Department of Pediatric Rheumatology and Immunology, Serbia.

Juvenile spondyloarthritis may be present in at least 3 subtypes of juvenile idiopathic arthritis according to the classification of the International League of Associations for Rheumatology. By contrast with spondyloarthritis in adults, juvenile spondyloarthritis starts with inflammation of peripheral joints and entheses in the majority of children, whereas sacroiliitis and spondylitis may develop many years after the disease onset. Peripheral joint involvement makes it difficult to differentiate juvenile spondyloarthritis from other juvenile idiopathic arthritis subtypes. Read More

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http://jultrason.pl/index.php/issues/volume-18-no-74/classif
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http://dx.doi.org/10.15557/JoU.2018.0033DOI Listing
January 2018
17 Reads

A Familial Case of Multicentric Carpotarsal Osteolysis Syndrome and Treatment Outcome.

J Pediatr Genet 2018 Dec 16;7(4):174-179. Epub 2018 Jun 16.

Department of Genetics, University of Alabama at Birmingham, Birmingham, Alabama, United States.

Multicentric carpotarsal osteolysis syndrome (MCTO) is a rare skeletal disorder caused by heterozygous mutations in the gene (v-maf musculoaponeurotic fibrosarcoma oncogene ortholog B). This is an autosomal dominant condition with a high frequency of sporadic cases. MCTO is characterized by osteolysis of the carpal, metacarpal, and tarsal bones beginning in early childhood with musculoskeletal rheumatologic symptoms such as pain and disability. Read More

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0038-1657760
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http://dx.doi.org/10.1055/s-0038-1657760DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6234043PMC
December 2018
12 Reads

A 67-Year-Old Man With Psoriatic Arthritis and New-Onset Dyspnea.

Chest 2018 Nov;154(5):e127-e134

Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore; University Medicine Cluster, Division of Respiratory and Critical Care Medicine, National University Hospital, National University Health System, Singapore. Electronic address:

A 67-year-old retired air force officer presented with a 6-month history of nonproductive cough, progressive exertional dyspnea, and weight loss. He was unable to walk beyond 100 m compared with his baseline of unlimited walking distance. He denied fever, hemoptysis, myalgia, or chest pain. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00123692183112
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http://dx.doi.org/10.1016/j.chest.2018.07.026DOI Listing
November 2018
25 Reads

Effect of high-intensity interval training on cardiovascular disease risk factors and body composition in psoriatic arthritis: a randomised controlled trial.

RMD Open 2018 11;4(2):e000729. Epub 2018 Oct 11.

Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.

Background: Psoriatic arthritis (PsA) is associated with an accumulation of cardiovascular disease (CVD) risk factors. The aim of this study was to evaluate the effect of high-intensity interval training (HIIT) on CVD risk factors in patients with PsA.

Methods: We randomly assigned 61 patients with PsA (41 women and 20 men) to an intervention group performing HIIT for 11 weeks or a control group who were instructed to not change their physical exercise habits. Read More

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http://rmdopen.bmj.com/lookup/doi/10.1136/rmdopen-2018-00072
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http://dx.doi.org/10.1136/rmdopen-2018-000729DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203095PMC
October 2018
20 Reads

[Differential diagnosis of axial spondyloarthritis-axSpA mimics].

Z Rheumatol 2019 Feb;78(1):31-42

Rheumazentrum Ruhrgebiet, Claudiusstr 45, 44649, Herne, Deutschland.

The classification of axial spondyloarthritis (axSpA) comprises the classical ankylosing spondylitis (AS), which is characterized by already existing structural changes in the sacroiliac joints, and the so-called non-radiographic axSpA (nr-axSpA), in which by definition such changes are not present. This distinction is based on the ASAS classification criteria for axSpA, which are however not suitable for a diagnosis. According to the current classification, spondyloarthritis (SpA) includes axSpA, which can be associated with psoriasis and/or chronic inflammatory bowel diseases (CED), such as Crohn's disease and ulcerative colitis, and peripheral SpA, which is further divided into SpA associated with psoriasis, partially synonymous with psoriatic arthritis (PsA), reactive SpA, partially synonymous with reactive arthritis (ReA) and SpA associated with CED, partially synonymous with arthritis associated with CED (e. Read More

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http://link.springer.com/10.1007/s00393-018-0557-8
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http://dx.doi.org/10.1007/s00393-018-0557-8DOI Listing
February 2019
5 Reads

Imaging in Psoriatic Arthritis-Insights About Pathogenesis of the Disease.

Curr Rheumatol Rep 2018 Oct 29;20(12):77. Epub 2018 Oct 29.

Division of Rheumatology, The Ottawa Hospital Research Institute, University of Ottawa, Ottawa, Canada.

Purpose Of Review: Heterogeneity is a hallmark of PsA as musculoskeletal inflammation can affect different tissues including the synovial joint, tendons, entheses, bursa, and bone.

Recent Findings: Relying on clinical examination for investigating underlying mechanisms in PsA is limited by the inherent inaccuracies of examination of the joints, enthesis, and spine. In addition, unlike synovial-centered diseases, histology is hard to obtain for the entheses and spine, limiting the knowledge for different manifestations of PsA. Read More

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http://dx.doi.org/10.1007/s11926-018-0793-6DOI Listing
October 2018
5 Reads

The thickening of flexor tendons pulleys: a useful ultrasonographical sign in the diagnosis of psoriatic arthritis.

J Ultrasound 2018 Dec 15;21(4):309-314. Epub 2018 Oct 15.

Institute of Radiology, Department of Medicine, University of Padua, Via Giustiniani, 2, 35128, Padua, Italy.

Purpose: To investigate the frequency of thickening of pulleys for flexor tendons in patients with early arthritis in their hands, and to evaluate it as a predictive sign of PsA.

Methods: A prospective observational study involving 228 consecutive patients presenting with recent onset of arthritis in their hands was conducted at rheumatology outpatient clinics in the Veneto region of Italy between October 2014 and September 2017. Diabetic patients were excluded because of the high frequency of trigger finger. Read More

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http://link.springer.com/10.1007/s40477-018-0325-2
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http://dx.doi.org/10.1007/s40477-018-0325-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237712PMC
December 2018
3 Reads

Mouse ear erosions: Psoriatic arthritis.

J Med Imaging Radiat Oncol 2018 Oct;62 Suppl 1:145

Department of Radiology, Concord Repatriation General Hospital, Concord, New South Wales, Australia.

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http://doi.wiley.com/10.1111/1754-9485.20_12786
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http://dx.doi.org/10.1111/1754-9485.20_12786DOI Listing
October 2018
6 Reads

Imaging in peripheral and axial psoriatic arthritis: contributions to diagnosis, follow-up, prognosis and knowledge of pathogenesis.

Clin Exp Rheumatol 2018 Sep-Oct;36 Suppl 114(5):24-34. Epub 2018 Oct 1.

Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Glostrup; and Dept. of Clinical Medicine, Faculty of Health and Medical Sciences, Univ. of Copenhagen, Copenhagen, Denmark.

Imaging in psoriatic arthritis (PsA) is rapidly evolving, and the use of sensitive modalities both in clinical research and routine care is increasing. This article provides an overview of current knowledge of different imaging methods in PsA, including current and possible future use in diagnosis, prognosis and clinical management, value in understanding pathogenesis, and latest activities to establish responsive imaging outcome measures. Much research remains to be performed concerning imaging in PsA, particularly on its optimal use in routine clinical care, the clinical consequences of imaging-detected subclinical disease, and specific and sensitive PsA imaging outcome measures. Read More

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January 2019
13 Reads

Enthesitis detection by ultrasound: where are we now?

Clin Exp Rheumatol 2018 Sep-Oct;36 Suppl 114(5):127-130. Epub 2018 Oct 1.

Rheumatology Department, APHP, Hôpital Ambroise Paré, INSERM U1173, Labex Inflamex, Université Versailles St-Quentin en Yvelines, Boulogne-Billancourt, France.

Over the last 25 years, ultrasound has been used to evaluate involvement at the entheses in spondyloarthritis (SpA) and psoriatic arthritis (PsA). Several studies have been reported indicating its value in detecting active inflammation at entheseal sites using both gray scale and Doppler findings. This review explores the recent literature and appraises the current knowledge and the unmet needs of enthesitis detection by ultrasound in the management of both SpA and PsA. Read More

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January 2019
7 Reads

Imaging detected tenosynovitis of metacarpophalangeal and wrist joints: an increasingly recognised characteristic of rheumatoid arthritis.

Clin Exp Rheumatol 2018 Sep-Oct;36 Suppl 114(5):131-138. Epub 2018 Oct 1.

Department of Rheumatology, Leiden University Medical Center; and Department of Rheumatology, Erasmus University Medical Center, Rotterdam, The Netherlands.

Tenosynovitis is traditionally recognised at physical examination in patients with inflammatory rheumatic diseases, such as, e.g. psoriatic arthritis and (longstanding) rheumatoid arthritis (RA). Read More

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January 2019
9 Reads

Miliary tuberculosis and herpes pharyngitis after a trip to a developing country: dangers of biologics.

BMJ Case Rep 2018 Oct 2;2018. Epub 2018 Oct 2.

Internal Medicine, Cooper University Hospital, Camden, New Jersey, USA.

The use of biologic drugs has expanded since its introduction in the late 1990s. With growing medical use and newer biologic drugs in development, opportunistic infections like remain important adverse effects. It carries major public health concerns, yet evidence-based clinical guidelines for more routine interval screening in patients taking immunosuppressants and exposed to tuberculosis (TB) are lacking. Read More

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http://dx.doi.org/10.1136/bcr-2018-224459DOI Listing
October 2018
9 Reads

Ultrasound Assessment of Changes in Nails in Psoriasis and Psoriatic Arthritis.

Biomed Res Int 2018 9;2018:8251097. Epub 2018 Sep 9.

Department of Pathophysiology, School of Medicine, Collegium Medicum, University of Warmia and Mazury, 10-900 Olsztyn, Poland.

Aim Of The Study: The aim of the study was to conduct an ultrasound (US) assessment of changes in fingernails in psoriatic patients with nail involvement.

Material: A total of 69 patients with psoriatic changes in nails participated in the study, including 38 patients with psoriasis (Ps) and 31 with psoriatic arthritis (PsA) and 30 people in the control group. A total of 988 nails were examined. Read More

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http://dx.doi.org/10.1155/2018/8251097DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151197PMC
January 2019
15 Reads

Three-dimensional nail imaging by optical coherence tomography: a novel biomarker of response to therapy for nail disease in psoriasis and psoriatic arthritis.

Clin Exp Dermatol 2018 Sep 23. Epub 2018 Sep 23.

Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK.

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http://dx.doi.org/10.1111/ced.13786DOI Listing
September 2018
2 Reads

Novel Concepts in Psoriatic Arthritis Management: Can We Treat to Target?

Curr Rheumatol Rep 2018 Sep 18;20(11):71. Epub 2018 Sep 18.

Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Botnar Research Centre, University of Oxford, Windmill Road, Oxford, OX3 7LD, UK.

Purpose Of Review: Psoriatic arthritis (PsA) is a chronic inflammatory spondyloarthritis that can cause progressive joint damage and irreversible disability. Advances in modern therapies, now mean a target of remission is an achievable goal in PsA. There is strong and consistent evidence that a treat-to-target (T2T) approach to PsA management results in better patient outcomes; however, the practicalities of incorporating this strategy into routine clinical practice remain a challenge. Read More

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http://dx.doi.org/10.1007/s11926-018-0781-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6153572PMC
September 2018
6 Reads

Advances in the treatment of uveitis in patients with spondyloarthritis - is it the time for biologic therapy?

Rom J Ophthalmol 2018 Apr-Jun;62(2):114-122

Department of Ophthalmology, University Emergency Hospital, Bucharest, Romania.

Spondyloarthritis (SpA) is a heterogeneous group of diseases that includes ankylosing spondylitis (AS), psoriatic arthritis (PsA), reactive arthritis (ReA), inflammatory bowel disease-associated spondyloarthritis (IBD-SpA), and undifferentiated spondyloarthritis (unSpA). This group of diseases shares several clinical, imaging, and genetic features; the integration of these diseases in the group of SpA is needed for an early diagnosis and a prompt treatment. Uveitis is the most common extra-articular manifestation of SpA. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117524PMC
February 2019
8 Reads

Enthesitis and Dactylitis in Psoriatic Disease: A Guide for Dermatologists.

Am J Clin Dermatol 2018 Dec;19(6):839-852

Hospital for Special Surgery, New York, NY, USA.

Psoriatic arthritis (PsA) is an inflammatory arthritis that is estimated to affect approximately 30% of patients with psoriasis. Enthesitis and dactylitis, two hallmarks of PsA, are associated with radiographic peripheral/axial joint damage and severe disease. Clinical symptoms of enthesitis include tenderness, soreness, and pain at entheses on palpation, whereas dactylitis is recognized by swelling of an entire digit that is different from adjacent digits. Read More

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http://link.springer.com/10.1007/s40257-018-0377-2
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http://dx.doi.org/10.1007/s40257-018-0377-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6267546PMC
December 2018
18 Reads

First metatarsophalangeal joint arthrodesis with two orthogonal two hole plates.

Acta Orthop Traumatol Turc 2018 Sep 11;52(5):363-366. Epub 2018 Aug 11.

Department of Trauma & Orthopaedics, University College London Hospitals NHS Foundation Trust, London, United Kingdom. Electronic address:

Objective: First MTP joint fusion is a reliable procedure for advanced arthritis for the first MTP joint. There are many techniques described. The purpose of our study is to report clinical, radiological, functional outcomes and complications of first metatarsophalangeal joint fusion with hand preparation of the joint and fixation with two orthogonal locking plates without a compression screw. Read More

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http://dx.doi.org/10.1016/j.aott.2018.06.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6204463PMC
September 2018
16 Reads

The GO-DACT protocol: a multicentre, randomized, double-blind, parallel-group study to compare the efficacy of golimumab in combination with methotrexate (MTX) versus MTX monotherapy.

Acta Reumatol Port 2018 Apr-Jun;43(2):80-92

Hospital de Santa Maria, CHLN; Unidade de Investigação em Reumatologia, Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Centro Académico de Medicina de Lisboa, Lisboa, Portugal.

The GO-DACT is an investigator-initiated, national, multicentric randomized placebo-controlled double-blinded trial, that assesses dactylitis as primary endpoint. Psoriatic arthritis patients naïve to methotrexate and biologic disease modifying anti-rheumatic drugs, with at least one active dactylitis, were assigned to golimumab in combination with methotrexate or placebo in combination with methotrexate, for 24 weeks. Both clinical (dactylitis severity score and the Leeds dactylitis index) and imaging (high resolution magnetic resonance imaging), among others, were assessed as outcomes. Read More

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August 2018
17 Reads

One year in review 2018: ultrasonography in rheumatoid arthritis and psoriatic arthritis.

Clin Exp Rheumatol 2018 Jul-Aug;36(4):519-525. Epub 2018 Jul 19.

Academic Rheumatology Center, Università degli Studi di Torino, Italy.

Ultrasound is playing an increasingly important role in the differential diagnosis and monitoring of rheumatoid arthritis (RA) and psoriatic arthritis (PsA). This technique is more sensitive and specific than clinical examination to detect active synovitis, and the identification of specific synovitis patterns enable differentiation of PsA from RA and other entities. Ultrasound verified inflammation changes along with clinical improvement during therapy, and ultrasound was shown to predict future clinical and structural outcomes thus complementing the clinical risk assessment of patients. Read More

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September 2018
3 Reads

Clinical outcomes and feasibility of the multidisciplinary management of patients with psoriatic arthritis: two-year clinical experience of a dermo-rheumatologic clinic.

Clin Rheumatol 2018 Oct 29;37(10):2741-2749. Epub 2018 Jul 29.

Clinica Medica, Dipartimento Scienze Cliniche e Molecolari, Università Politecnica delle Marche, Via Tronto 10/A, 60126, Ancona, Italy.

Psoriatic arthritis (PsA) is a chronic inflammatory autoimmune arthritis, occurring in patients with psoriasis (Pso), that may affect the whole musculoskeletal system but also nails, eye, and gastrointestinal tract. Dermatologists and rheumatologists usually manage Pso and PsA separately, but early diagnosis and integrated management could achieve better outcomes of both skin and musculoskeletal manifestations, thus improving the health-related quality of life (HRQoL) of patients. In this work, we have described a model of integrated dermo-rheumatologic approach for the early diagnosis of PsA and to present the outcomes of the multidisciplinary management of PsA patients after 48 weeks of follow-up. Read More

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http://dx.doi.org/10.1007/s10067-018-4238-4DOI Listing
October 2018
5 Reads

Resolution of synovitis and arrest of catabolic and anabolic bone changes in patients with psoriatic arthritis by IL-17A blockade with secukinumab: results from the prospective PSARTROS study.

Arthritis Res Ther 2018 07 27;20(1):153. Epub 2018 Jul 27.

Department of Internal Medicine 3 - Rheumatology and Immunology, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) and Universitätsklinikum Erlangen, Ulmenweg 18, 91054, Erlangen, Germany.

Background: Although the effects of interleukin-17A (IL-17A) inhibition on the signs and symptoms of psoriatic arthritis (PsA) are well defined, little is known about its impact of local inflammatory and structural changes in the joints. The PSARTROS study was designed to elucidate the effects of IL-17A inhibition on inflammation and bone changes in joints affected by PsA.

Methods: This was a prospective open-label study in 20 patients with active PsA receiving 24 weeks of treatment with the IL-17A inhibitor secukinumab. Read More

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https://arthritis-research.biomedcentral.com/articles/10.118
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http://dx.doi.org/10.1186/s13075-018-1653-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063019PMC
July 2018
11 Reads

Satisfaction and discontent of Polish patients with biological therapy of rheumatic diseases: results of a multi-center questionnaire study.

Reumatologia 2018 30;56(3):140-148. Epub 2018 Jun 30.

First Division of Rheumatology, Hospital for Rheumatology and Rehabilitation, Goczałkowice Zdrój, Poland.

Objectives: Biologics are medications widely applied in the management of inflammatory rheumatic diseases. The drugs were found to be effective but their application is associated with some disadvantages. Medication with biologics is relatively expensive, and in Poland, it is carried out in specialized centers. Read More

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http://dx.doi.org/10.5114/reum.2018.76901DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052366PMC
June 2018
13 Reads

Assessment of subclinical atherosclerosis in psoriatic arthritis patients without clinically overt cardiovascular disease or traditional atherosclerosis risk factors.

Turk Kardiyol Dern Ars 2018 07;46(5):358-365

Department of Cardiology, Hacettepe University Faculty of Medicine, Ankara, Turkey.

Objective: Cardiovascular disease (CVD) is more prevalent in almost all patients with chronic inflammatory musculoskeletal diseases than in their healthy counterparts. The aim of this study was to assess the presence of subclinical atherosclerosis in patients with psoriatic arthritis (PsA) in comparison with patients with rheumatoid arthritis (RA) and healthy controls.

Methods: A total of 30 patients with PsA, 30 patients with RA, and 30 healthy controls were enrolled in this parallel group study. Read More

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http://dx.doi.org/10.5543/tkda.2018.36169DOI Listing
July 2018
7 Reads

Anti-TNF modulation reduces myocardial inflammation and improves cardiovascular function in systemic rheumatic diseases.

Int J Cardiol 2018 Nov 25;270:253-259. Epub 2018 Jun 25.

University of Oxford Centre for Clinical Magnetic Resonance Research (OCMR), Division of Cardiovascular Medicine, Radcliffe Department of Medicine, John Radcliffe Hospital, Oxford, UK; First Department of Cardiology, Aristotle University of Thessaloniki, AHEPA Hospital, Thessaloniki, Greece. Electronic address:

Background: Rheumatoid arthritis (RA), ankylosing spondylitis (AS) and psoriatic arthritis (PsA) are common disorders associated with increased rates of cardiovascular disease (CVD), but the contribution of cytokine-induced inflammation to impaired cardiovascular function in these conditions remains poorly understood.

Objectives: We assessed the effect of anti-TNF therapy on myocardial and vascular function, myocardial tissue characteristics and perfusion in inflammatory arthropathy and systemic rheumatic disease (IASRD) patients, using cardiovascular magnetic resonance (CMR).

Methods: 20 RA patients, 7 AS patients, 5 PsA patients without previously known CVD scheduled to commence anti-TNF therapy and 8 RA patients on standard disease modifying antirheumatic drugs underwent CMR at 1. Read More

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http://dx.doi.org/10.1016/j.ijcard.2018.06.099DOI Listing
November 2018
8 Reads

Psoriatic Arthritis Sonographic Enthesitis Instruments: A Systematic Review of the Literature.

J Rheumatol 2019 Jan 15;46(1):43-56. Epub 2018 Jul 15.

From the University of Toronto and Toronto Western Hospital; University of Toronto Lupus Clinic, Toronto Western Hospital, Centre for Prognosis Studies in the Rheumatic Diseases; University Health Network; Women's College Hospital, Toronto; University of Ottawa, Faculty of Medicine, Rheumatology, and Ottawa Hospital Research Institute, Ottawa, Ontario, Canada; University of Florida College of Medicine, Jacksonville, Florida, USA.

Objective: As part of the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) ultrasound working group, we performed a systematic review of the literature to assess the evidence and knowledge gaps in scoring instruments of enthesitis in psoriatic arthritis (PsA).

Methods: A systematic search of PubMed, EMBase, and Cochrane databases was performed. The search strategy was constructed to find original publications containing terms related to ultrasound, enthesitis, spondyloarthritis (SpA) or PsA. Read More

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http://dx.doi.org/10.3899/jrheum.171466DOI Listing
January 2019
39 Reads
3.190 Impact Factor

What is metacarpophalangeal joint swelling in psoriatic arthritis? Ultrasound findings and reliability assessment.

Clin Exp Rheumatol 2018 Sep-Oct;36(5):896-899. Epub 2018 Jun 14.

Department of Rheumatology, Hospital Universitario La Paz, Madrid, Spain.

Objectives: To evaluate by ultrasound (US) the frequency and reliability of peritenon extensor tendon inflammation (PTI) and intra articular synovitis (IAS) in metacarpophalangeal joints (MCPj) of psoriatic arthritis (PsA) patients.

Methods: 27 PsA patients with clinical involvement of MCPj were consecutively included. Presence of PTI and IAS were evaluated by grey-scale (GS) and power Doppler (PD). Read More

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January 2019
10 Reads

Clinical and ultrasonographic predictors for achieving minimal disease activity in patients with psoriatic arthritis: the UPSTREAM (Ultrasound in PSoriatic arthritis TREAtMent) prospective observational study protocol.

BMJ Open 2018 Jul 10;8(7):e021942. Epub 2018 Jul 10.

Dipartimento di Scienze Cliniche e Biologiche, Università degli Studi di Torino, Torino, Italy.

Introduction: Psoriatic arthritis (PsA) occurs in 10%-15% of people with psoriasis and accounts for 10%-20% of early arthritis clinics referral. Only a few prognostic factors of therapeutic response in patients with PsA have been identified. In the last years, the role of imaging has grown up and the European League Against Rheumatism recognised that ultrasound (US) has higher sensitivity than clinical examination to detect inflammatory disease activity. Read More

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http://dx.doi.org/10.1136/bmjopen-2018-021942DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082450PMC
July 2018
7 Reads

Destructive psoriatic arthritis of the temporomandibular joint: a clinical case, an overview of the pathophysiology and its differential diagnoses.

Cranio 2018 Jul 9:1-7. Epub 2018 Jul 9.

h Faculty of Sciences, Oral Medicine and Pathology , School of Dental Medicine, Universidad Mayor , Santiago , Chile.

Background Clinical assessments and uniplanar images in temporomandibular disorders are not always entirely reliable. This predicament is especially important when clinicians need to determine the nature of temporomandibular joint disease, particularly when clinical features are not helpful in determining the diagnosis. Clinical presentation A 63-year-old female patient presented with mild pain in her right TMJ. Read More

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https://www.tandfonline.com/doi/full/10.1080/08869634.2018.1
Publisher Site
http://dx.doi.org/10.1080/08869634.2018.1484575DOI Listing
July 2018
10 Reads

Entheseal involvement in patients with systemic lupus erythematosus: an ultrasound study.

Rheumatology (Oxford) 2018 10;57(10):1822-1829

Department of Clinical and Molecular Sciences, Rheumatology Unit, Carlo Urbani Hospital, Polytechnic University of Marche, Jesi, Ancona, Italy.

Objectives: The main objective of this study is to explore the prevalence and distribution of entheseal US changes in a cohort of SLE patients, taking as controls a group including both PsA patients and healthy subjects. The secondary objective is to investigate the correlation between the US findings and the clinical and serological data in SLE patients.

Methods: Clinical and US assessment of quadriceps, patellar and Achilles tendons, and plantar fascia entheses were performed by independent rheumatologists on 65 patients with SLE, 50 patients with PsA and 50 healthy subjects. Read More

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http://dx.doi.org/10.1093/rheumatology/key189DOI Listing
October 2018
23 Reads
4.475 Impact Factor

Autoimmune temporomandibular arthropathy: diagnostic considerations.

Gen Dent 2018 Jul-Aug;66(4):56-61

The etiology of degenerative processes of the temporomandibular joint (TMJ) remains unclear, as they could be the result of trauma, infection, or autoimmune disease. Improving the diagnosis of autoimmune disease, whether the TMJ is the primary site or secondarily affected by a systemic disease, is of fundamental importance in selecting treatment that will address the causes rather than just relieve the symptoms. The purposes of this article are to discuss autoimmunity as an etiologic factor in degenerative processes of the TMJ by presenting clinical cases and to highlight the importance of imaging and serologic examinations for diagnosis. Read More

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January 2019
1 Read

Influence of Axial Involvement on Clinical Characteristics of Psoriatic Arthritis: Analysis from the Corrona Psoriatic Arthritis/Spondyloarthritis Registry.

J Rheumatol 2018 Oct 1;45(10):1389-1396. Epub 2018 Jul 1.

From the Swedish Medical Center and University of Washington, Seattle, Washington; Novartis Pharmaceuticals Corp., East Hanover, New Jersey; Corrona LLC, Waltham, Massachusetts; University of California San Diego, La Jolla, California; Allergy, Immunology and Rheumatology Division, University of Rochester Medical Center, Rochester; New York University School of Medicine, New York, New York, USA.

Objective: We analyzed the characteristics of patients with psoriatic arthritis (PsA) with and without axial involvement in the US-based Corrona Psoriatic Arthritis/Spondyloarthritis Registry.

Methods: All patients were included who had PsA and data on axial involvement, defined as physician-reported presence of spinal involvement at enrollment, and/or radiograph or magnetic resonance imaging showing sacroiliitis. Demographics, clinical measures, patient-reported outcomes, and treatment characteristics were assessed at enrollment. Read More

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http://dx.doi.org/10.3899/jrheum.171094DOI Listing
October 2018
19 Reads

The Coexistence of Systemic Lupus Erythematosus and Psoriasis: Is It Possible?

Acta Med Indones 2018 Apr;50(2):144-150

Department of Internal Medicine, Faculty of Medicine, Airlanggan University - dr. Soetomo Hospital, Surabaya, Indonesia.

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with various clinical disorders and frequent exacerbations. Psoriasis vulgaris is a common skin disorder which affect 1-3% of general populations. The pathophysiology regarding the coexistence of these diseases is not fully understood. Read More

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April 2018
3 Reads

Axial psoriatic arthritis: the impact of underdiagnosed disease on outcomes in real life.

Clin Rheumatol 2018 Dec 13;37(12):3443-3448. Epub 2018 Jun 13.

Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology, Hacettepe University, Ankara, Turkey.

Psoriatic arthritis (PsA) may affect different joints, including the spine. The prevalence of spinal involvement is variable depending on the definition and a subset of patients have been identified in cohorts that do not have clinical features of axial disease and yet have imaging findings. Still, there is not a consensus on how and when to screen axial disease. Read More

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http://dx.doi.org/10.1007/s10067-018-4173-4DOI Listing
December 2018
22 Reads
1.774 Impact Factor

Spondyloarthritis: new insights into clinical aspects, translational immunology and therapeutics.

Curr Opin Rheumatol 2018 Sep;30(5):526-532

Section of Musculoskeletal Disease, Leeds Institute of Molecular Medicine, University of Leeds, NIHR Leeds Musculoskeletal Biomedical Research Unit, Chapel Allerton Hospital, Leeds, UK.

Purpose Of Review: The spondyloarthopathies (SpA), which encompass related diseases that were originally viewed as autoimmune, are now known to have a strong innate immune or autoinflammatory initiation phase characterized by disease localization to tissue-specific sites based on the nuances and microanatomy and immunology of those sites. This review covers recent translational advances in the field of SpA.

Recent Findings: Imaging studies in SpA continue to add support for the pivotal role of enthesitis in disease initiation and expression. Read More

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http://dx.doi.org/10.1097/BOR.0000000000000529DOI Listing
September 2018
3 Reads

The impact of high intensity interval training on disease activity and patient disease perception in patients with psoriatic arthritis: A randomized controlled trial.

Arthritis Care Res (Hoboken) 2018 Jun 8. Epub 2018 Jun 8.

Dept. of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.

Objective: The aim of this study was to evaluate the impact of high intensity interval training (HIIT) on disease activity and patient disease perception in patients with psoriatic arthritis (PsA), and evaluating if a potential effect could be sustained for a longer period.

Methods: We randomly assigned 67 PsA patients (43 women and 24 men) to an intervention group performing HIIT for 11 weeks or a control group who were instructed to not change their physical exercise habits. Outcomes were assessed at three and nine months with the patient global assessment (PGA), fatigue, and pain measured on a 100 mm visual analog scale and the composite disease activity score of 44 joints (DAS44) was calculated. Read More

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http://dx.doi.org/10.1002/acr.23614DOI Listing
June 2018
8 Reads