2,999 results match your criteria Psittacosis


The Application Value of Metagenomic and Whole-Genome Capture Next-Generation Sequencing in the Diagnosis and Epidemiological Analysis of Psittacosis.

Front Cell Infect Microbiol 2022 6;12:872899. Epub 2022 Jun 6.

College of Pulmonary and Critical Care Medicine, Chinese People's Liberation Army (PLA) General Hospital, Beijing, China.

Background: To evaluate the value of metagenomic next-generation sequencing (mNGS) for the early diagnosis of psittacosis, and to investigate its epidemiology by whole-genome capture.

Methods: Twenty-one bronchoalveolar lavage fluid (BALF) and blood samples of 16 psittacosis patients from multiple centers during August 2019 to September 2021 were analyzed retrospectively. mNGS with normal datasets (10 M 75-bp single-end reads after sequencing) and larger datasets (30 M 150-bp paired-end reads after sequencing) as well as quantitative real-time polymerase chain reaction (qPCR) were used to detect the pathogen. Read More

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Clinical characteristics of 14 cases of severe Chlamydia psittaci pneumonia diagnosed by metagenomic next-generation sequencing: A case series.

Medicine (Baltimore) 2022 Jun 17;101(24):e29238. Epub 2022 Jun 17.

Department of Respiratory and Critical Care Medicine, Zhongshan People's Hospital, Zhongshan, People's Republic of China.

Introduction: The objective of this study was to explore the clinical, laboratory, and imaging features of severe Chlamydia psittaci pneumonia in order to improve early diagnosis and treatment success rates.

Methods: We conducted a retrospective record review of 14 cases of severe Chlamydia psittaci pneumonia diagnosed by metagenomic next-generation sequencing technology in our hospital. We extracted and analyzed data on the clinical symptoms and signs, contact history, laboratory investigations, chest computed tomography, treatment, and clinical outcomes. Read More

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Human-to-human transmission of Chlamydia psittaci in China, 2020: an epidemiological and aetiological investigation.

Lancet Microbe 2022 May 23. Epub 2022 May 23.

Key Laboratory of Aetiology and Epidemiology of Emerging Infectious Diseases in Universities of Shandong, Shandong First Medical University and Shandong Academy of Medical Sciences, Tai'an, China; School of Public Health, Shandong First Medical University and Shandong Academy of Medical Sciences, Tai'an, China. Electronic address:

Background: Chlamydia psittaci can infect a wide range of avian species, occasionally causing psittacosis (also known as parrot fever) in humans. Most human psittacosis cases are associated with close contact with pet birds or poultry. In December, 2020, an outbreak of severe community-acquired pneumonia of unknown aetiology was reported in a hospital in Shandong province, China, and some of the patients' close contacts had respiratory symptoms. Read More

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[0ne case report of Chlamydia psittaci pneumonia].

Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi 2022 Apr;40(4):300-303

Shandong Academy of Occupational Health and Occupational Medicine Occupational Pulmonary Disease Department, Jinan 250001, China.

This paper reported a case of severe Chlamydia psittaci pneumonia. The patient had a clear history of contact with sick poultry. The clinical manifestations were dry cough, fever and respiratory failure. Read More

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Successful Treatment of Severe Community-Acquired Pneumonia caused by Chlamydia Psittaci: a Case Report.

Clin Lab 2022 May;68(5)

Background: Community acquired pneumonia is a common and deadly condition, which remains a major cause of morbidity and mortality throughout the world. Chlamydia psittaci pneumonia is responsible for less than 5% of community-acquired pneumonia with a fatality rate of 1%. Nonetheless, it is underestimated due to low awareness of the disease and atypical clinical presentation in a majority of the cases. Read More

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Psittacosis with a reversed halo sign.

Indian J Med Res 2021 04;154(4):650

Department of General Medicine, Juntendo University School of Medicine, Tokyo 113-8421, Japan.

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Psittacosis with a reversed halo sign.

Indian J Med Res 2022 Mar 21. Epub 2022 Mar 21.

Department of General Medicine, Juntendo University School of Medicine, Tokyo 113-8421, Japan.

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Severe Pneumonia Complicated by Rhabdomyolysis: A Case Series.

Infect Drug Resist 2022 6;15:873-881. Epub 2022 Mar 6.

Department of Respiratory and Critical Care Medicine, Zhongshan People's Hospital, Zhongshan, People's Republic of China.

Purpose: To explore the clinical characteristics, diagnosis, and treatment of severe pneumonia complicated by rhabdomyolysis and to improve the success rate of treatment.

Patients And Methods: The clinical characteristics, diagnosis, treatment, and outcomes of four patients with severe pneumonia complicated by rhabdomyolysis diagnosed by metagenomic next-generation sequencing (mNGS) in our hospital were analyzed retrospectively.

Results: All four patients were male, aged 46-64 years, and all had a history of bird contact. Read More

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Polymorphic Membrane Protein 17G of Mediated the Binding and Invasion of Bacteria to Host Cells by Interacting and Activating EGFR of the Host.

Front Immunol 2021 31;12:818487. Epub 2022 Jan 31.

Key Lab of Animal Epidemiology and Zoonoses of Ministry of Agriculture and Rural Affairs, College of Veterinary Medicine, China Agricultural University, Beijing, China.

() is an obligate intracellular, gram-negative bacterium, and mainly causes systemic disease in psittacine birds, domestic poultry, and wild fowl. The pathogen is threating to human beings due to closely contacted to employees in poultry industry. The polymorphic membrane proteins (Pmps) enriched in includes six subtypes (A, B/C, D, E/F, G/I and H). Read More

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The prevalence of Chlamydia psittaci in confiscated Psittacidae in Colombia.

Prev Vet Med 2022 Mar 3;200:105591. Epub 2022 Feb 3.

Animal Science Faculty, Universidad de Ciencias Aplicadas y Ambientales (UDCA), Bogotá D.C., 111166, Colombia. Electronic address:

Chlamydia psittaci is a highly zoonotic bacteria distributed worldwide; it is responsible for psittacosis, one of the most important infectious diseases affecting the Psittacidae, mostly parrots. This work was aimed at determining C. psittaci prevalence and genotype in 177 parrots confiscated in Colombia; cloacal swab (166) and faecal (177) samples were analysed from birds confiscated and housed in a Temporary Wildlife Reception Centre (Centro de Reception de Fauna Temporal). Read More

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Aetiology of severe community acquired pneumonia in adults identified by combined detection methods: a multi-centre prospective study in China.

Emerg Microbes Infect 2022 Dec;11(1):556-566

Department of Pulmonary and Critical Care Medicine, Fuzhou General Hospital, Fuzhou, People's Republic of China.

Severe Community Acquired Pneumonia (SCAP) challenges public health globally. Considerable improvements in molecular pathogen testing emerged in the last few years. Our prospective study combinedly used traditional culture, antigen tests, PCR and mNGS in SCAP pathogen identification with clinical outcomes. Read More

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December 2022

Clustering cases of pneumonia mimicking COVID-19 pneumonia.

World J Clin Cases 2021 Dec;9(36):11237-11247

Department of Radiology, The Second Xiangya Hospital, Central South University, Changsha 410011, Hunan Province, China.

Background: The onset symptoms of people infected by can mimic the coronavirus disease 2019 (COVID-19). However, the differences in laboratory tests and imaging features between psittacosis and COVID-19 remain unknown.

Aim: To better understand the two diseases and then make an early diagnosis and treatment. Read More

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December 2021

Clinical Symptoms and Outcomes of Severe Pneumonia Caused by in Southwest China.

Front Cell Infect Microbiol 2021 6;11:727594. Epub 2022 Jan 6.

Department of ICU, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China.

Here, we aimed to retrospectively analyze the clinical characteristics of 27 patients with severe pneumonia caused by between January 2019 and April 2021 in southwest China. To this end, we collected data on the exposure history, clinical symptoms, laboratory examination, imaging characteristics, evolution, etiology, treatment, and outcomes to suggest a better diagnosis and prevention system. Our results showed that a metagenomic next-generation sequencing test could provide early diagnosis. Read More

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January 2022

A Rare Bird: Diagnosis of Psittacosis Meningitis by Clinical Metagenomic Next-Generation Sequencing.

Open Forum Infect Dis 2021 Dec 8;8(12):ofab555. Epub 2021 Dec 8.

Department of Medicine, Division of Infectious Diseases, University of California Los Angeles, Los Angeles, California, USA.

Psittacosis is a zoonotic infectious disease caused by the transmission of ; it often presents as a pulmonary infection but rarely as disseminated disease. Because diagnoses of psittacosis are often underreported due to infrequent pathogen-specific testing, clinical metagenomic next-generation sequencing may be helpful to diagnose such an uncommon syndrome. Read More

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December 2021

Gestational Psittacosis With Secondary Hemophagocytic Syndrome: A Case Report and Literature Review.

Front Med (Lausanne) 2021 18;8:755669. Epub 2021 Nov 18.

Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Anhui Medical University, Hefei, China.

Gestational psittacosis and hemophagocytic syndrome (HPS) are rare clinical diseases. In this article, a case of gestational psittacosis concomitant with secondary HPS was reported. An analysis was performed on the clinical characteristics, signs, laboratory findings, progression, diagnosis, and treatment of a patient with gestational psittacosis concomitant with secondary HPS. Read More

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November 2021

Sixteen cases of severe pneumonia caused by in South China investigated via metagenomic next-generation sequencing.

J Med Microbiol 2021 Nov;70(11)

Department of Respiratory Medicine, The First People's Hospital of Changde City, Hunan, PR China.

is an important cause of community-acquired pneumonia (CAP). The spectrum of CAP due to ranges from mild, self-limited to acute respiratory failure and the early identification of this disease can be challenging. Metagenomic next-generation sequencing (mNGS) of bronchoalveolar lavage fluid has the potential to improve the pathogen identification in severe CAP. Read More

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November 2021

Pregnancy combined with severe pneumonia caused by Chlamydia psittaci infection - a case report.

Ginekol Pol 2021;92(10):743-744

Department of Emergency, the Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.

Objective: Chlamydia psittaci (Cps) feeds on gram-negative aerobic cells. Respiratory inhalation of Cps or close contact with infected animals can cause psittacosis in humans. Given its challengeable early diagnosis and rapid progression, misdiagnosis or improper antibacterial drugs may lead to multi-organ dysfunction with a high mortality. Read More

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Identification of Campylobacter jejuni and Chlamydia psittaci from cockatiel (Nymphicus hollandicus) using metagenomics.

BMC Genomics 2021 Nov 6;22(1):797. Epub 2021 Nov 6.

Avian Disease Division, Animal and Plant Quarantine Agency, 177 Hyeoksin 8-ro, Gyeongsangbuk-do, 39660, Gimcheon-si, Republic of Korea.

Background: In July 2015, the carcasses of 11 cockatiels were submitted for disease diagnosis to the Avian Disease Division of the Animal and Plant Quarantine Agency of Korea. The cockatiels, which appeared dehydrated and underweight, had exhibited severe diarrhea and 22 % mortality over 2 weeks. Traditional diagnosis did not reveal the causes of these symptoms. Read More

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November 2021

Clinical metagenomic sequencing for rapid diagnosis of pneumonia and meningitis caused by .

World J Clin Cases 2021 Sep;9(26):7693-7703

Department of Respiratory and Critical Care Medicine, Changzhou Second People's Hospital Affiliated to Nanjing Medical University, Changzhou 213164, Jiangsu Province, China.

Background: () is a gram-negative intracellular parasitic pathogenic bacterium that can infect avian and mammalian hosts, including humans. The detection of infections typically relies on traditional antigen-based immunoassays or serological testing that often lack sensitivity and/or specificity. Metagenomic next generation sequencing (mNGS) is an emerging tool for diagnosis. Read More

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September 2021

Development and comparative evaluation of droplet digital PCR and quantitative PCR for the detection and quantification of Chlamydia psittaci.

J Microbiol Methods 2021 11 27;190:106318. Epub 2021 Sep 27.

ICAR-National Research Centre on Meat, Chengicherla, Hyderabad 500092, India. Electronic address:

Chlamydia psittaci is a zoonotic pathogen mainly transmitted by psittacine birds and poultry. The low shedding rate of the pathogen in the apparently healthy birds and human clinical cases may result in false-negative results. In the present study, a droplet digital PCR (ddPCR) assay was developed and compared with optimized quantitative PCR (qPCR) for the detection of C. Read More

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November 2021

[Clinical and imaging features of pneumonia: an analysis of 48 cases in China].

Zhonghua Jie He He Hu Xi Za Zhi 2021 Oct;44(10):886-891

Department of General Medicine, Nanjing Second Hospital, Nanjing 210003, China.

To explore the clinical characteristics, imaging findings, laboratory tests and treatment strategies for pneumonia. From January 1, 2019 to January 20, 2021, 48 cases of Psittacosis from 11 hospitals in China were diagnosed via metagenomic next-generation sequencing(mNGS). The data of all patients on occupational history, clinical manifestations, laboratory tests, chest computed tomography(CT)findings, treatment outcomes and prognosis were retrospectively analyzed. Read More

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October 2021

Application of metagenomic next-generation sequencing in the diagnosis of severe pneumonia caused by Chlamydia psittaci.

BMC Pulm Med 2021 Sep 23;21(1):300. Epub 2021 Sep 23.

Department of Respiratory Medicine, Dongyang Hospital Affiliated to Wenzhou Medical University, Dongyang, 322100, Zhejiang Province, China.

Purpose: Psittacosis is a zoonotic infectious disease caused by the transmission of the bacterium Chlamydia psittaci (C. psittaci) from birds to humans. Infections in humans mainly present as community-acquired pneumonia (CAP). Read More

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September 2021

[ pneumonia complicated with rhabdomyolysis: a case report and literature review].

Zhonghua Jie He He Hu Xi Za Zhi 2021 Sep;44(9):806-811

Guanzhou Institute of Respiratory Health, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou 510120, China.

To analyze the clinical characteristics and the diagnosis and treatment of pneumonia complicated with rhabdomyolysis. We reported a case of pneumonia complicated with rhabdomyolysis. We did a literature review on the published reports between January 1978 and May 2020 by searching with the key words of "psittacosis" or "i" and "rhabdomyolysis" in the PubMed database (time frame: January 1, 1967 to May 30, 2020). Read More

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September 2021

Undiagnosed Cases of Human Pneumonia Following Exposure to from an Infected Rosella Parrot.

Pathogens 2021 Jul 30;10(8). Epub 2021 Jul 30.

School of Animal and Veterinary Science, University of Adelaide, Roseworthy, SA 5371, Australia.

This report describes two cases of occupational exposure to following dissection of an infected Rosella (). The infections (with one of them resulting in diagnosed pneumonia and hospitalisation) were undiagnosed during routine medical investigations but later established due to epidemiological and clinical evidence, and molecular testing of the archived Rosella' specimens. This case report stresses the importance of correct application and interpretation of diagnostic tests and the need to raise awareness about this zoonotic pathogen among medical practitioners and people exposed to potential animal carriers. Read More

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A Review of Chlamydial Infections in Wild Birds.

Pathogens 2021 Jul 28;10(8). Epub 2021 Jul 28.

Centre for Integrative Ecology, School of Life and Environmental Sciences, Deakin University, Geelong, VIC 3216, Australia.

The are a globally distributed genus of bacteria that can infect and cause disease in a range of hosts. Birds are the primary host for multiple chlamydial species. The most well-known of these is , a zoonotic bacterium that has been identified in a range of wild and domesticated birds. Read More

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Investigation of chlamydophilosis from naturally infected cats.

J Vet Sci 2021 Nov 3;22(6):e67. Epub 2021 Aug 3.

Department of Clinical Pathology, Faculty of Veterinary Medicine, Universitas Gadjah Mada, Yogyakarta 55281, Indonesia.

Background: , formerly known as var. , is frequently associated with ocular, respiratory, and occasionally reproduction tract infections. Even though the infection is sometimes asymptomatic, it potentially results in a latent immunosuppressive infection. Read More

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November 2021

Real-time fluorometric and end-point colorimetric isothermal assays for detection of equine pathogens C. psittaci and equine herpes virus 1: validation, comparison and application at the point of care.

BMC Vet Res 2021 Aug 19;17(1):279. Epub 2021 Aug 19.

NSW Department of Primary Industries, Elizabeth Macarthur Agricultural Institute, Menangle, NSW, 2568, Australia.

Background: C. psittaci has recently emerged as an equine abortigenic pathogen causing significant losses to the Australian Thoroughbred industry, while Equine herpesvirus-1 (EHV-1) is a well-recognized abortigenic agent. Diagnosis of these agents is based on molecular assays in diagnostic laboratories. Read More

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Genetic and phenotypic analysis of the pathogenic potential of two novel Chlamydia gallinacea strains compared to Chlamydia psittaci.

Sci Rep 2021 08 13;11(1):16516. Epub 2021 Aug 13.

Department of Bacteriology and Epidemiology, Wageningen Bioveterinary Research, Lelystad, The Netherlands.

Chlamydia gallinacea is an obligate intracellular bacterium that has recently been added to the family of Chlamydiaceae. C. gallinacea is genetically diverse, widespread in poultry and a suspected cause of pneumonia in slaughterhouse workers. Read More

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Severe psittacosis progressing to suspected organizing pneumonia and the role of corticosteroids.

Respir Med Case Rep 2021 27;34:101486. Epub 2021 Jul 27.

Tamworth Rural Referral Hospital, Tamworth, Australia.

Background: Psittacosis is a systemic disease usually with respiratory involvement, caused by the obligate intracellular bacterium . Exposure to birds, the main zoonotic reservoir, is a major risk factor for infection. The spectrum of disease is highly variable, ranging from subclinical infection to severe pneumonia requiring mechanical ventilation. Read More

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Severe Chlamydia psittaci pneumonia: clinical characteristics and risk factors.

Ann Palliat Med 2021 Jul;10(7):8051-8060

Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.

Background: Psittacosis ranges from a mild illness to fulminant severe pneumonia with multi-organ failure. It's crucial to understand the clinical characteristics and identify risk factors for a better outcome.

Methods: We conducted a retrospective analysis designed to identify risk factors for severe Chlamydia psittaci pneumonia (C. Read More

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