2,957 results match your criteria Psittacosis

Metagenomic diagnosis of severe psittacosis using multiple sequencing platforms.

BMC Genomics 2021 Jun 2;22(1):406. Epub 2021 Jun 2.

Chinese PLA Center for Disease Control and Prevention, 20 Dongda Street, Fengtai District, 100071, Beijing, China.

Background: Chlamydia psittaci is an avian pathogen that can cause lethal human infections. Diagnosis of C. psittaci pneumonia is often delayed due to nonspecific clinical presentations and limited laboratory diagnostic techniques. Read More

View Article and Full-Text PDF

A patient with psittacosis from a pigeon: A reminder of the importance of detailed interviews and relative bradycardia.

IDCases 2021 18;25:e01164. Epub 2021 May 18.

Department of General Medicine, Juntendo University Faculty of Medicine, Tokyo, Japan.

A 43-year-old man was brought to our hospital with fever. The initial diagnosis was bacterial pneumonia, and ampicillin/sulbactam was administered. However, defervescence was not achieved, and relative bradycardia was observed. Read More

View Article and Full-Text PDF

Global prevalence of chlamydial infections in birds: A systematic review and meta-analysis.

Prev Vet Med 2021 Jul 5;192:105370. Epub 2021 May 5.

Faculty of Veterinary Medicine, Khon Kaen University, Thailand.

Chamydia species are bacterial pathogens that can infect a wide range of animal hosts including humans. In birds, Chlamydia psittaci is a leading cause of chlamydial infections (avian chlamydiosis) and is a zoonotic pathogen causing human psittacosis. The objectives of this study were to estimate the global prevalence of chlamydial infections in birds, to assess heterogeneity of the prevalence for some particular characteristics (continents, bird orders, specimen types, and diagnostic techniques), and to determine the trend of the prevalence over time. Read More

View Article and Full-Text PDF

Clinical Analysis of Metagenomic Next-Generation Sequencing Confirmed Pneumonia: A Case Series and Literature Review.

Infect Drug Resist 2021 16;14:1481-1492. Epub 2021 Apr 16.

Department of Pharmacy, The Second Xiangya Hospital, Central South University; Institute of Clinical Pharmacy, Central South University, Changsha, People's Republic of China.

Introduction: infection is a zoonotic infectious disease, which mainly inhaled through the lungs when exposed to the secretions of poultry that carry pathogenic bacteria. The traditional respiratory specimens or serological antibody testing is slow, and the false-negative rate is high. Metagenomic next-generation sequencing (mNGS) gives a promising rapid diagnosis tool. Read More

View Article and Full-Text PDF

Psittacosis in a traveller.

J Travel Med 2021 Apr 14. Epub 2021 Apr 14.

German Center for Infection Research (DZIF), Partner Site Hamburg-Lübeck-Borstel-Riems, Germany.

View Article and Full-Text PDF

Polymorphic membrane protein 20G: A promising diagnostic biomarker for specific detection of Chlamydia psittaci infection.

Microb Pathog 2021 Jun 10;155:104882. Epub 2021 Apr 10.

Reproductive Medicine Center, Department of Obstetrics and Gynecology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China. Electronic address:

Psittacosis is a zoonotic disease caused by Chlamydia psittaci (C. psittaci), leading to high risk for animal industry and human health. Lack of reliable commercial kits and effective vaccines is hampering control of C. Read More

View Article and Full-Text PDF

Presence and shedding of in waterfowl in a rehabilitation facility and in the wild in New Zealand.

N Z Vet J 2021 Jul 7;69(4):240-246. Epub 2021 May 7.

Tāwharau Ora, School of Veterinary Science, Massey University, Palmerston North, New Zealand.

Aims: To determine the frequency of infection, shedding dynamics of , and genotype diversity in waterfowl temporarily resident in a rehabilitation facility and in mallards in the wild.

Methods: Conjunctival-choanal-cloacal swabs were collected from apparently healthy captive wild mallards (; n = 114) and paradise shelducks (; n = 10) temporarily housed at a waterfowl breeding and rehabilitation facility (Wellington, NZ) and from wild mallards in Palmerston North (n = 50), and Southland (n = 50). DNA extracted from the swabs was analysed using quantitative PCR (qPCR) high-resolution melt curve (HRM) analysis, targeting the gene of

Results: Of the captive waterfowl, 39/114 (34%) mallards and 6/10 (60%) paradise shelducks were positive for as were 24/100 (24%) wild mallards. Read More

View Article and Full-Text PDF

Use of Real-Time PCR for Chlamydia psittaci Detection in Human Specimens During an Outbreak of Psittacosis - Georgia and Virginia, 2018.

MMWR Morb Mortal Wkly Rep 2021 Apr 9;70(14):505-509. Epub 2021 Apr 9.

Psittacosis is typically a mild febrile respiratory illness caused by infection with the bacterium Chlamydia psittaci and usually transmitted to humans by infected birds (1). On average, 11 psittacosis cases per year were reported in the United States during 2000-2017. During August-October 2018, the largest U. Read More

View Article and Full-Text PDF

Multi-organ failure with necrotic skin lesions due to infection with Chlamydia psittaci.

Int J Infect Dis 2021 May 3;106:262-264. Epub 2021 Apr 3.

Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands; Department of Hematology, Erasmus MC, Erasmus University Medical Center, Rotterdam, The Netherlands. Electronic address:

Presented is a patient with dyspnea and painful ulcers finally resulting in multi-organ failure. A detailed history resulted in positive PCR testing for Chlamydia psittaci. We emphasize the importance of a definitive history in establishing the correct diagnosis. Read More

View Article and Full-Text PDF

A New SNP-Based Genotyping Method for : Application to Field Samples for Quick Identification.

Microorganisms 2021 Mar 17;9(3). Epub 2021 Mar 17.

Laboratory for Animal Health, Bacterial Zoonosis Unit, ANSES Maisons-Alfort, Paris-Est University, 94706 Paris, France.

(.) is the causative agent of avian chlamydiosis and human psittacosis. In this study, we extracted single-nucleotide polymorphisms (SNPs) from the whole genome sequences of 55 strains and identified eight major lineages, most of which are host-related. Read More

View Article and Full-Text PDF

A recombinase polymerase amplification-based assay for rapid detection of Chlamydia psittaci.

Poult Sci 2021 Feb 28;100(2):585-591. Epub 2020 Nov 28.

Guangdong Provincial Animal Virus Vector Vaccine Engineering Technology Research Center, College of Animal Science, South China Agricultural University, Guangzhou 510642, P.R. China; Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA. Electronic address:

Chlamydia psittaci is a zoonotic agent of systemic wasting disease in birds and atypical pneumonia in mammalians including humans, constituting a public health risk. A rapid diagnostic assay would be beneficial in screening C. psittaci in the field. Read More

View Article and Full-Text PDF
February 2021

Clinical characteristics of Chlamydia psittaci pneumonia.

Chin Med J (Engl) 2021 Jan 5;134(3):353-355. Epub 2021 Jan 5.

Department of Pulmonary and Critical Care Medicine, The Fourth Affiliated Hospital, Zhejiang University School of Medicine, Yiwu, Zhejiang 322000, China.

View Article and Full-Text PDF
January 2021

A 25-year retrospective study of in association with equine reproductive loss in Australia.

J Med Microbiol 2021 Feb;70(2)

Asia Pacific Centre for Animal Health, The Melbourne Veterinary School, The University of Melbourne, Parkville, Victoria 3010, Australia.

is primarily a pathogen of birds but can also cause disease in other species. Equine reproductive loss caused by has recently been identified in Australia where cases of human disease were also reported in individuals exposed to foetal membranes from an ill neonatal foal in New South Wales. The prevalence of in association with equine reproductive over time and in different regions of Australia is not known. Read More

View Article and Full-Text PDF
February 2021

[A case report of critical psittaci pneumonia diagnosed by next-generation sequencing].

Zhonghua Nei Ke Za Zhi 2020 Dec;59(12):989-991

Department of Critical Care Medicine, Northern Jiangsu People's Hospital, Yangzhou 225001, China.

View Article and Full-Text PDF
December 2020

Species, sex and geographic variation in chlamydial prevalence in abundant wild Australian parrots.

Sci Rep 2020 11 24;10(1):20478. Epub 2020 Nov 24.

Centre for Integrative Ecology, School of Life and Environmental Sciences, Deakin University, 75 Pigdons Road, Waurn Ponds, VIC, 3216, Australia.

Chlamydia psittaci (order: Chlamydiales) is a globally distributed zoonotic bacterium that can cause potentially fatal disease in birds and humans. Parrots are a major host, yet prevalence and risk factors for infection in wild parrots are largely unknown. Additionally, recent research suggests there is a diverse range of novel Chlamydiales circulating in wildlife. Read More

View Article and Full-Text PDF
November 2020

Occupational Respiratory Infections.

Clin Chest Med 2020 12;41(4):739-751

Division of Tuberculosis Elimination, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, 1600 Clifton Road Northeast, MS US12-4, Atlanta, GA 30333, USA.

Occupational respiratory infections can be caused by bacterial, viral, and fungal pathogens. Transmission in occupational settings can occur from other humans, animals, or the environment, and occur in various occupations and industries. In this article, we describe 4 occupationally acquired respiratory infections at the focus of NIOSH investigations over the last decade: tuberculosis (TB), influenza, psittacosis, and coccidioidomycosis. Read More

View Article and Full-Text PDF
December 2020

Fatal infection in a domestic kitten.

J Vet Diagn Invest 2021 Jan 28;33(1):101-103. Epub 2020 Oct 28.

Wyoming State Veterinary Diagnostic Laboratory, University of Wyoming, Laramie, WY.

has not been reported to cause disease in domestic cats, to our knowledge. In contrast, infection is common in domestic cats and typically results in conjunctivitis, upper respiratory tract infection, and less frequently pneumonia. Herein, we report the pathologic findings and diagnostic features of a fatal case of psittacosis in a 7-wk-old domestic kitten. Read More

View Article and Full-Text PDF
January 2021

Development of a Plasmid Shuttle Vector System for Genetic Manipulation of Chlamydia psittaci.

mSphere 2020 08 26;5(4). Epub 2020 Aug 26.

Department of Infectious Diseases and Microbiology, University of Lübeck, Lübeck, Germany.

The obligate intracellular bacterium is a known avian pathogen causing psittacosis in birds and is capable of zoonotic transmission. In human pulmonary infections, can cause pneumonia associated with significant mortality if inadequately diagnosed and treated. Although intracellular manipulates host cell organelles for its replication and survival, it has been difficult to demonstrate host-pathogen interactions in infection due to the lack of easy-to-handle genetic manipulation tools. Read More

View Article and Full-Text PDF

Chlamydial diversity and predictors of infection in a wild Australian parrot, the Crimson Rosella (Platycercus elegans).

Transbound Emerg Dis 2021 Mar 14;68(2):487-498. Epub 2020 Jul 14.

Centre for Integrative Ecology, School of Life and Environmental Sciences, Deakin University, Waurn Ponds, VIC, Australia.

Members of the Chlamydia genus are known to cause disease in both humans and animals. A variety of other species in the order Chlamydiales are increasingly being discovered and emerging as potential pathogens, yet there are scarce data on the diversity, prevalence and impacts of these pathogens in wild birds. To address this gap, we investigated which Chlamydiales species are present in a wild population of a common Australian parrot, the Crimson Rosella (Platycercus elegans). Read More

View Article and Full-Text PDF

Acute respiratory distress syndrome during a pandemic-an obvious diagnosis?

Lancet Infect Dis 2020 07;20(7):873

Intensive Care Unit, Department of Internal Medicine, Medical University of Graz, Graz, Austria.

View Article and Full-Text PDF

Chlamydiosis in a Gouldian Finch ().

Avian Dis 2020 06;64(2):216-222

Turlock Branch, University of California, Davis, California Animal Health & Food Safety Laboratory System, Turlock, CA 95380,

Avian chlamydiosis is an infection caused by obligate intracellular and Gram-negative bacteria belonging to the family and has been reported in more than 450 avian species distributed in 30 orders. In particular, a high prevalence of infection has been demonstrated in wild passerine populations, including both asymptomatic and clinically ill individuals, suggesting a role of these avian species as important carriers. In May 2018, avian chlamydiosis was diagnosed in a 1-year-old male Gouldian finch () at the Turlock Branch of the California Animal Health and Food Safety Laboratory System. Read More

View Article and Full-Text PDF

Evaluation of a tandem Chlamydia psittaci Pgp3 multiepitope peptide vaccine against a pulmonary chlamydial challenge in mice.

Microb Pathog 2020 Oct 13;147:104256. Epub 2020 May 13.

Institute of Pathogenic Biology, Hengyang Medical College, University of South China, Hunan Provincial Key Laboratory for Special Pathogens Prevention and Control, Hengyang, China; Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, Hengyang, 421001, China. Electronic address:

Chlamydia psittaci is the pathogen of psittacosis, and it has emerged as a significant public health threat. Because most infections are easily overlooked, a vaccine is recognized as the best solution to control the spread of C. psittaci. Read More

View Article and Full-Text PDF
October 2020

Next-generation sequencing diagnosis of severe pneumonia from fulminant psittacosis with multiple organ failure: a case report and literature review.

Ann Transl Med 2020 Mar;8(6):401

Department of Respiratory and Critical Care Medicine, Shenzhen People's Hospital, First Affiliated Hospital of Southern University of Science and Technology, Second Clinical Medical College of Jinan University, Shenzhen Institute of Respiratory Diseases, Shenzhen Key Laboratory of Respiratory Diseases, Shenzhen 518020, China.

This study includes a retrospective analysis of the diagnosis and treatment of a case of severe pneumonia from fulminant psittacosis with multiple organ failure. Next-generation sequencing (NGS) of the pathogen was conducted. The purpose of this study was to summarize the clinical, laboratory, and imaging characteristics of the case and to improve understanding of the value of NGS in the diagnosis of severe community-acquired pneumonia (CAP). Read More

View Article and Full-Text PDF

Metagenomic next-generation sequencing in the diagnosis of severe pneumonias caused by Chlamydia psittaci.

Infection 2020 Aug 20;48(4):535-542. Epub 2020 Apr 20.

Department of Critical Care Medicine, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, No. 321 Zhongshan Road, Nanjing, 210008, Jiangsu Province, China.

Purpose: Chlamydia psittaci infection in humans can lead to serious clinical manifestations, including severe pneumonia, adult respiratory distress syndrome, and, rarely, death. Implementation of metagenomic next-generation sequencing (mNGS) gives a promising new tool for diagnosis. The clinical spectrum of severe psittacosis pneumonia is described to provide physicians with a better understanding and to highlight the rarity and severity of severe psittacosis pneumonia. Read More

View Article and Full-Text PDF

Human psittacosis in Japan: notification trends and differences in infection source and age distribution by gender, 2007 to 2016.

Ann Epidemiol 2020 04 25;44:60-63. Epub 2020 Mar 25.

Infectious Disease Surveillance Center, National Institute of Infectious Diseases, Tokyo, Japan.

Purpose: Psittacosis is a bacterial zoonosis caused by Chlamydia (Chlamydophila) psittaci that infects birds. Although potentially fatal, infections can be reduced by controlling the source of infection. We therefore described the epidemiology of psittacosis, focusing on the infection source. Read More

View Article and Full-Text PDF

PmpD-N Exacerbated Chicken Macrophage Function by Triggering Th2 Polarization and the TLR2/MyD88/NF-κB Signaling Pathway.

Int J Mol Sci 2020 Mar 15;21(6). Epub 2020 Mar 15.

Key Lab of Animal Epidemiology and Zoonosis of the Ministry of Agriculture, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China.

The polymorphic membrane protein D (PmpD) is a highly conserved outer membrane protein which plays an important role in pathogenesis during infection. In this study, we evaluated the ability of the N-terminus of PmpD (PmpD-N) to modulate the functions of chicken macrophages and the signaling pathway(s) involved in PmpD-N-induced Toll-like receptors (TLRs), as well as interleukin (IL)-6 and IL-10 cytokine secretions. Thus, HD11 macrophages were treated with exogenous and intracellular PmpD-N of . Read More

View Article and Full-Text PDF

The application of metagenomic next-generation sequencing in diagnosing Chlamydia psittaci pneumonia: a report of five cases.

BMC Pulm Med 2020 Mar 17;20(1):65. Epub 2020 Mar 17.

Department of Respiratory and Critical Care Medicine, Dongfang Hospital of Xiamen University, Fuzhou General Hospital of Fujian Medical University, The 900th Hospital of the Joint Logistic Support Force, PLA, Gulou, Fuzhou, 350025, China.

Background: Chlamydia psittaci pneumonia is a zoonotic infectious disease caused by Chlamydia psittaci. Diagnostic tools, including culture, serologic test and PCR-based methods, are available but prone to false negative results.

Case Presentation: This report included five cases of Chlamydia psittaci pneumonia. Read More

View Article and Full-Text PDF

Chlamydia psittaci in fulmars on the Faroe Islands: a causative link to South American psittacines eight decades after a severe epidemic.

Microbes Infect 2020 09 3;22(8):356-359. Epub 2020 Mar 3.

Section of Clinical Bacteriology, Department of Medical Sciences, Uppsala University, SE-751 85 Uppsala, Sweden; Department of Clinical Microbiology, Uppsala University Hospital, SE-751 85 Uppsala, Sweden. Electronic address:

A psittacosis epidemic linked to fulmar hunting occurred on the Faroe Islands in the 1930s. This study investigates a plausible explanation to the 20% human mortality in this outbreak. Phylogenetic analysis showed that Chlamydia psittaci isolated from fulmars were closely related to the highly virulent 6BC strains from psittacines and are compatible with an acquisition by fulmars of an ancestor of the 6BC clade in the 1930s. Read More

View Article and Full-Text PDF
September 2020

Animal sources for zoonotic transmission of psittacosis: a systematic review.

BMC Infect Dis 2020 Mar 4;20(1):192. Epub 2020 Mar 4.

Centre for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, the Netherlands.

Background: Human psittacosis, caused by Chlamydia (C.) psittaci, is likely underdiagnosed and underreported, since tests for C. psittaci are often not included in routine microbiological diagnostics. Read More

View Article and Full-Text PDF