3,920 results match your criteria Pseudotumor Cerebri


Do Most Patients With a Spontaneous Cerebrospinal Fluid Leak Have Idiopathic Intracranial Hypertension?

J Neuroophthalmol 2019 Feb 8. Epub 2019 Feb 8.

Departments of Ophthalmology (SB, NJN, and VB), Otolaryngology-Head and Neck Surgery (JML), Radiology and Imaging Sciences (AMS), Neurological Surgery (NMO and NJN), and Neurology (NJN and VB), Emory University School of Medicine, Atlanta, Georgia.

Background: The association between cerebrospinal fluid (CSF) leaks at the skull base and raised intracranial pressure (ICP) has been reported since the 1960s. It has been suggested that spontaneous CSF leaks might represent a variant of idiopathic intracranial hypertension (IIH). We review the evidence regarding the association between spontaneous CSF leaks and IIH, and the role of ICP in the pathophysiology of nontraumatic skull base defects. Read More

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http://dx.doi.org/10.1097/WNO.0000000000000761DOI Listing
February 2019
1 Read

RE: "An Estimation of the Risk of Pseudotumor Cerebri Among Users of the Levonorgestrel Intrauterine Device".

Neuroophthalmology 2019 Feb 27;43(1):67-69. Epub 2018 Jul 27.

Pharmacovigilance, Medical Affairs & Pharmacovigilance, Pharmaceuticals, Bayer Oy, Espoo, Finland.

The current letter to the editor describes some of the limitations of Valenzuela et al.'s study on the association between levonorgestrel-releasing intrauterine system use and pseudotumor cerebri/idiopathic intracranial hypertension and further reinforces the authors' interpretations of the findings. Read More

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http://dx.doi.org/10.1080/01658107.2018.1465439DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351020PMC
February 2019
1 Read

Idiopathic Intracranial Hypertension in a Mother and Pre-pubertal Twins.

Neuroophthalmology 2019 Feb 26;43(1):49-52. Epub 2018 Jun 26.

Department of Ophthalmology and Visual Neurosciences, University of Minnesota, Minneapolis, Minnesota, USA.

Idiopathic intracranial hypertension is a syndrome of elevated intracranial pressure without an identifiable cause. The majority of cases appear to be sporadic, and incidence is highest in obese women of childbearing age. The role of genetics in the pathophysiology of the disease is unclear, and familial cases are rare. Read More

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http://dx.doi.org/10.1080/01658107.2018.1480047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351011PMC
February 2019

Ganglion Cell Complex Analysis as a Potential Indicator of Early Neuronal Loss in Idiopathic Intracranial Hypertension.

Neuroophthalmology 2019 Feb 19;43(1):10-17. Epub 2018 Jun 19.

The New England Eye Center, Tufts Medical Center, Boston, Massachusetts, USA.

Reliable visual field testing is the gold standard in identifying future vision loss in patients with Idiopathic Intracranial hypertension (IIH). However, when field performance is unreliable, GCC analysis may be useful. We evaluated IIH patients over three visits: initial visit, follow-up visit and a third visit, almost 1 year later. Read More

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http://dx.doi.org/10.1080/01658107.2018.1476558DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351016PMC
February 2019

Minocycline-induced transient depersonalization: A case report.

SAGE Open Med Case Rep 2019 17;7:2050313X18823827. Epub 2019 Jan 17.

Division of Dermatology, McGill University, Montreal, QC, Canada.

Minocycline is a medication commonly used for the treatment of acne vulgaris. The central nervous system-induced side effects of minocycline include headaches, pseudotumor cerebri, ataxia, and vestibular dysfunction. Many minocycline-related side effects have been presented in the literature, however, reports of depersonalization symptoms induced by the medication are rare. Read More

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http://dx.doi.org/10.1177/2050313X18823827DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349971PMC
January 2019
1 Read

Pattern of Idiopathic Intracranial Hypertension in Indian Population.

Ann Indian Acad Neurol 2019 Jan-Mar;22(1):47-51

Department of Neuromedicine, Medical College, Kolkata, West Bengal, India.

Objective: To evaluate the clinical and demographic profile, laboratory parameters and outcomes of Idiopathic Intracranial hypertension (IIH) patients from Indian subpopulation.

Materials And Method: We did a prospective study on patients who fulfilled the revised diagnostic criteria for Primary pseudotumor cerebri syndrome in adults and children, proposed by Friedman et al in 2013. All patients were examined for BMI, papilloedema, extraocular muscle movement, opening CSF pressure and underwent MRI, MR venography of brain and perimetry. Read More

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http://dx.doi.org/10.4103/aian.AIAN_116_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327693PMC
January 2019

Pseudotumour cerebri associated with mycoplasma pneumoniae infection and treatment with levofloxacin: a case report.

BMC Pediatr 2019 Jan 5;19(1). Epub 2019 Jan 5.

Pediatric Highly Intensive Care Unit, Fondazione IRCSS Ca' Granda Ospedale Maggiore Policlinico, and a Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy.

Background: Idiopathic intracranial hypertension (IIH), also known as pseudotumour cerebri syndrome (PTCS), is characterized by the presence of signs and symptoms of raised intracranial pressure without evidence of any intracranial structural cause and with normal cerebrospinal fluid microscopy and biochemistry. Obesity, various systemic diseases and endocrine conditions, and a number of medications are known to be risk factors for PTCS. The medications commonly associated with PTCS are amiodarone, antibiotics, corticosteroids, cyclosporine, growth hormone, oral contraceptives, vitamin A analogues, lithium, phenytoin, NSAIDs, leuprolide acetate, and some neuroleptic drugs. Read More

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https://bmcpediatr.biomedcentral.com/articles/10.1186/s12887
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http://dx.doi.org/10.1186/s12887-018-1371-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320575PMC
January 2019
3 Reads

Optimization of 3D phase contrast venography for the assessment of the cranio-cervical venous system at 1.5 T.

Neuroradiology 2019 Jan 4. Epub 2019 Jan 4.

Section Biomedical Imaging, Molecular Imaging North Competence Center (MOIN CC), Department for Radiology and Neuroradiology, University Medical Center, Arnold Heller Street 3, Building 41, 24105, Kiel, Germany.

Purpose: The aim of this work was to optimize a three-dimensional (3D) phase-contrast venography (PCV) product MR pulse sequence in order to obtain clinically reliable images with less artifacts for an improved depiction of the cranio-cervical venous vessels.

Methods: Starting from the product sequence, the 3D PCV protocol was optimized in eight steps with respect to the velocity encoding (V) direction and value, slice thickness, reduction of susceptibility artifacts and arterial contamination, gradient mode and radio-frequency (RF)-spoiling, B-Shimming, asymmetric echo technique and RF-pulse type, and flip angle. The product and optimized protocol was used to perform 3D PCV in 12 healthy male volunteers with a median age of 50 years using a state-of-the-art 1. Read More

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http://dx.doi.org/10.1007/s00234-018-2146-6DOI Listing
January 2019
2 Reads

One year in review 2018: Behçet's syndrome.

Clin Exp Rheumatol 2018 Nov-Dec;36(6 Suppl 115):13-27. Epub 2018 Dec 13.

Division of Rheumatology, Department of Internal Medicine, School of Medicine, Istanbul Universtiy-Cerrahpasa, Turkey.

New epidemiologic studies from Poland, Jordan, Algeria, Taiwan and Korea highlight the geographic differences in incidence, prevalence and clinical features of Behçet's syndrome (BS). A study from Austria comparing clinical manifestations of their BS patients with different countries of origin suggest that environmental factors may be important in the disease phenotype of BS. New genetic association studies dealing with the innate and acquired aspects of BS prevailed during 2017 and novel susceptibility and regulatory factors were described. Read More

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December 2018
11 Reads

Predictors of Primary Intracranial Hypertension in Children Using a Newly Suggested Opening Pressure Cutoff of 280 mm HO.

Pediatr Neurol 2019 Feb 19;91:27-33. Epub 2018 Oct 19.

Department of Emergency Medicine, Department of Informatics, Boston Children's Hospital, Boston, Massachusetts. Electronic address:

Objectives: We assessed the clinical characteristics of primary intracranial hypertension (PIH) in children using a newly recommended threshold for cerebrospinal fluid opening pressure (280 mm HO).

Method: Cross-sectional study of patients age ≤21 years who had a lumbar puncture done for evaluation of PIH. Patients were excluded if lumbar puncture was done for a suspected infection, seizure, mental status changes, multiple sclerosis, or Guillain-Barre syndrome. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S08878994183071
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http://dx.doi.org/10.1016/j.pediatrneurol.2018.09.013DOI Listing
February 2019
8 Reads

Pseudotumor cerebri in childhood and adolescence: data from a specialized service.

Arq Neuropsiquiatr 2018 Nov;76(11):751-755

Universidade Federal de São Paulo, Departamento de Pediatria, Unidade de Reumatologia Pediátrica, São Paulo SP, Brasil.

Objective: To report cases of children and adolescents diagnosed with pseudotumor cerebri associated or not with rheumatic disease.

Methods: This was a retrospective study based on medical reports of 29 patients, up to 18 years of age and diagnosed with pseudotumor cerebri, followed up in the Pediatric Rheumatology and Neurology outpatient clinics of a tertiary hospital, until December 2016.

Results: Among the 29 patients diagnosed with pseudotumor cerebri, 51. Read More

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http://dx.doi.org/10.1590/0004-282X20180131DOI Listing
November 2018
4 Reads

Mesalazine treatment causing resolution of intracranial hypertension secondary to ulcerative colitis: A case report.

Medicine (Baltimore) 2018 Dec;97(49):e13365

Department of Ophthalmology, Fondation Ophtalmologique Adolphe de Rothschild.

Rationale: The association between intracranial hypertension (ICH) and ulcerative colitis (UC) is rare. We report the unusual case of a male patient with UC and ICH in whom both conditions resolved with mesalazine therapy.

Patient Concerns: A 48-year-old Caucasian man presented to our department in June 2016 for decreased vision, transient visual obscuration, pulsatile tinnitus and headaches of 7 months duration. Read More

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http://dx.doi.org/10.1097/MD.0000000000013365DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310519PMC
December 2018
3 Reads

Herpes simplex encephalitis and pseudotumour cerebri due to ısotretinoin.

J Pak Med Assoc 2018 Dec;68(12):1833-11835

Department of Internal Medicine, Medical School, Firat University, Elazig Turkey.

Isotretinoin can have significant adverse reactions on multiple systems. We report a unique case of pseudotumour cerebri and herpes encephalitis resulting due to isotretinoin. A 19-year-old female patient was admitted to our clinic, presenting with headache, nausea, vomiting and fever since three days. Read More

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December 2018
12 Reads

Pseudotumor Cerebri Syndrome is the Best Term for This Condition.

Pediatr Neurol 2018 Oct 16;87:9-10. Epub 2018 Aug 16.

Departments of Neurology and Ophthalmology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania; Division of Ophthalmology, Neuro-ophthalmology Service, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania; Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S08878994183087
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http://dx.doi.org/10.1016/j.pediatrneurol.2018.08.018DOI Listing
October 2018
6 Reads

Eliminating the Secret Handshake: A Plea for Clarity in Medical Terminology.

Authors:
E Steve Roach

Pediatr Neurol 2018 Oct 16;87:7-8. Epub 2018 Aug 16.

The University of Texas Dell Medical School, Austin, Texas. Electronic address:

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http://dx.doi.org/10.1016/j.pediatrneurol.2018.08.019DOI Listing
October 2018
1 Read

Suprasellar Epidermoid Cyst Originating from the Infundibulum: Case Report and Literature Review.

Cureus 2018 Aug 29;10(8):e3226. Epub 2018 Aug 29.

Neurological Surgery, George Washington University, Washington DC, USA.

Epidermoid cysts account for a small fraction of intracranial brain tumors, most commonly found in the cerebellopontine angle and parasellar cisterns. Here we present a rare case of an epidermoid cyst located in the suprasellar region, specifically originating from the infundibulum. Only one additional case with an epidermoid cyst originating within the pituitary stalk has been previously reported in the literature. Read More

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http://dx.doi.org/10.7759/cureus.3226DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6263494PMC
August 2018
1 Read

Non-Syndromic Craniosynostosis Mimicking Primary Pseudotumor Cerebri Syndrome.

Headache 2019 Feb 25;59(2):264-265. Epub 2018 Nov 25.

Department of Pediatric Neurology, UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1111/head.13450DOI Listing
February 2019
1 Read

Skull Base Dural Thickness and Relationship to Demographic Features: A Postmortem Study and Literature Review.

J Neurol Surg B Skull Base 2018 Dec 5;79(6):614-620. Epub 2018 Jun 5.

Department of Neurosurgery, University of Iowa Hospitals and Clinics, Iowa City, Iowa, United States.

Dural membrane is an important anatomic structure that surrounds and protects the entire central nervous system. Physical properties of the dura have many pathophysiological and therapeutic implications in cranial surgery, especially skull base disorders. The aim of this study is to investigate variation in skull base dural thickness and correlation with different demographic parameters. Read More

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0038-1651501
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http://dx.doi.org/10.1055/s-0038-1651501DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6239876PMC
December 2018
9 Reads

Pseudotumor cerebri and lung cancer-associated jugular vein thrombosis: Role of anatomical variations of torcular herophili.

eNeurologicalSci 2018 Dec 2;13:18-20. Epub 2018 Nov 2.

Laboratory of Neural Circuitry, Graduate School of Brain Science, Doshisha University, Japan.

A 71-year-old male appeared at the facility complaining of disturbance of consciousness and bilateral papilledema. The laboratory test revealed anemia and coagulation abnormality. A physical examination and magnetic resonance imaging (MRI) of the brain with and without gadolinium showed no abnormalities. Read More

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http://dx.doi.org/10.1016/j.ensci.2018.11.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222035PMC
December 2018
1 Read

Clinical Features of Pediatric Idiopathic Intracranial Hypertension and Applicability of New ICHD-3 Criteria.

Front Neurol 2018 28;9:819. Epub 2018 Sep 28.

Child Neurology Unit, Department of Neuroscience and Neurorehabilitation, Headache Center, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.

Idiopathic intracranial hypertension (IIH) is characterized by intracranial pressure >28 cmHO in the absence of identifiable causes. Aim of this paper is to describe the clinical phenotype of pediatric IIH and to analyze the applicability of ICHD-3 criteria in comparison to the ICHD-2. We conducted a retrospective analysis of full clinical data of pediatric patients diagnosed with IIH between January 2007 and June 2018. Read More

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https://www.frontiersin.org/article/10.3389/fneur.2018.00819
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http://dx.doi.org/10.3389/fneur.2018.00819DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6190892PMC
September 2018
9 Reads

Atypical Anti-MOG syndrome with aseptic meningoencephalitis and pseudotumor cerebri-like presentations.

Mult Scler Relat Disord 2019 Jan 3;27:30-33. Epub 2018 Oct 3.

UT Southwestern Medical Center, 5323 Harry Hines Blvd Dallas, Texas, TX 75235, United States.

Objective: To describe 2 atypical cases with Anti-MOG antibody related demyelinating syndrome.

Methodology: Case series.

Results: We present two cases. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S22110348183036
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http://dx.doi.org/10.1016/j.msard.2018.10.003DOI Listing
January 2019
3 Reads

European headache federation guideline on idiopathic intracranial hypertension.

J Headache Pain 2018 Oct 8;19(1):93. Epub 2018 Oct 8.

Metabolic Neurology, Institute of Metabolism and Systems Research, University of Birmingham, Edgbaston, UK.

Background: Idiopathic Intracranial Hypertension (IIH) is characterized by an elevation of intracranial pressure (ICP no identifiable cause. The aetiology remains largely unknown, however observations made in a number of recent clinical studies are increasing the understanding of the disease and now provide the basis for evidence-based treatment strategies.

Methods: The Embase, CDSR, CENTRAL, DARE and MEDLINE databases were searched up to 1st June 2018. Read More

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http://dx.doi.org/10.1186/s10194-018-0919-2DOI Listing
October 2018
8 Reads

Delayed presentation of iatrogenic ventriculoperitoneal shunt transection following laparoscopic weight loss surgery in a patient with idiopathic intracranial hypertension.

Ann R Coll Surg Engl 2019 Jan 5;101(1):e5-e7. Epub 2018 Oct 5.

King's College Hospital, Department of Neurosurgery , London , UK.

Idiopathic intracranial hypertension is strongly associated with central obesity and consequential raised intra-abdominal pressure. If left untreated it poses significant risk to vision and can eventually cause blindness. Owing to its pathophysiology, this condition is managed by both medical and surgical specialities. Read More

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http://dx.doi.org/10.1308/rcsann.2018.0147DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6303825PMC
January 2019
1 Read

Intracranial Hypertension Secondary to Cervical Dural Arteriovenous Fistula.

Asian J Neurosurg 2018 Jul-Sep;13(3):854-857

Department of Neurosurgery, The Walton Centre NHS Foundation Trust, Liverpool, L9 7LJ, UK.

Idiopathic intracranial hypertension (IIH) is a disease of mainly unknown etiology. Latest theories as to the pathogenesis have postulated a final common pathway of cerebral venous hypertension secondary to venous outflow impairment leading to decreased cerebrospinal fluid absorption. We present the case of a 42-year-old female who was treated for several years for headache and for approximately 12 months for IIH until appropriate imaging showed a right-sided cervical dural arteriovenous fistula (AVF) at the level of C4. Read More

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http://dx.doi.org/10.4103/ajns.AJNS_328_16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6159076PMC
October 2018
1 Read

Co-occurrence of acute ophthalmoplegia (without ataxia) and idiopathic intracranial hypertension.

Eur J Ophthalmol 2018 Oct 3:1120672118803532. Epub 2018 Oct 3.

University of Malaya, Kuala Lumpur, Malaysia.

Background: Acute ophthalmoparesis without ataxia was designated as 'atypical Miller Fisher syndrome' as it presents with progressive, relatively symmetrical ophthalmoplegia, but without ataxia nor limb weakness, in the presence of anti-GQ1b antibody. Idiopathic intracranial hypertension is characterized by signs of raised intracranial pressure occurring in the absence of cerebral pathology, with normal composition of cerebrospinal fluid and a raised opening pressure of more than 20 cmHO during lumbar puncture. We aim to report a rare case of acute ophthalmoplegia with co-occurrence of raised intracranial pressure. Read More

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http://journals.sagepub.com/doi/10.1177/1120672118803532
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http://dx.doi.org/10.1177/1120672118803532DOI Listing
October 2018
4 Reads

Epidural Blood Patch for Postdural Puncture Headache due to Lumboperitoneal Shunt Placement in a Patient With Pseudotumor Cerebri: A Case Report.

A A Pract 2018 Sep 26. Epub 2018 Sep 26.

From the Department of Anesthesiology, University of Kansas Medical Center, Kansas City, Kansas.

The epidural blood patch (EBP) is commonly used to treat postdural puncture headaches (PDPHs) from spinal anesthesia, dural puncture with epidural anesthesia, and diagnostic and therapeutic lumbar puncture. We present a case of a patient with pseudotumor cerebri (idiopathic intracranial hypertension) who had a lumboperitoneal shunt placed for persistent headaches and subsequently developed symptoms similar to a PDPHs that were successfully treated with an EBP. While the exact mechanism by which our patient was experiencing PDPH symptoms is unknown, the EBP administration proved to be both therapeutic and diagnostic by ruling out shunt catheter malfunction through a resolution of symptoms. Read More

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http://dx.doi.org/10.1213/XAA.0000000000000897DOI Listing
September 2018
5 Reads

Changes in End-Tidal Carbon Dioxide Partial Pressure Alter Venous Sinus Pressure Measurements in Idiopathic Intracranial Hypertension.

World Neurosurg 2018 Dec 26;120:495-499. Epub 2018 Sep 26.

Department of Neurological Surgery, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA.

Background: In the diagnosis of venous stenosis associated with idiopathic intracranial hypertension, previous studies have identified significant differences when venous pressures are measured under conscious sedation versus general anesthesia. No previous reports have investigated the effect that respiratory parameters may have on cerebral venous sinus pressure and the associated trans-stenosis pressure gradient.

Case Description: Two patients with idiopathic intracranial hypertension were retrospectively identified from a prospective database wherein venous manometry was performed as part of a venous stenting procedure with waveform recording during changes in end-tidal carbon dioxide level (EtCO). Read More

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http://dx.doi.org/10.1016/j.wneu.2018.09.117DOI Listing
December 2018
1 Read

Prognostic value of JAK2V617F mutation in pseudotumor cerebri associated with cerebral venous sinus thrombosis.

Acta Neurol Scand 2019 Feb 11;139(2):166-171. Epub 2018 Oct 11.

Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Objectives: To examine the clinical characteristics and prognosis of cerebral venous sinus thrombosis (CVST) that presented as pseudotumor cerebri (PTC) patients with JAK2V617F mutation.

Methods: Medical records of all consecutive patients that presented with PTC and a JAK2V617F mutation who were treated were retrospectively reviewed. Data regarding demographics and ocular presenting symptoms and signs, neurological signs, hematological factors treatment, and prognosis were collected. Read More

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http://dx.doi.org/10.1111/ane.13032DOI Listing
February 2019
10 Reads

Endovascular Treatment for Venous Sinus Stenosis in Idiopathic Intracranial Hypertension: An Observational Study of Clinical Indications, Surgical Technique, and Long-Term Outcomes.

World Neurosurg 2019 Jan 21;121:e165-e171. Epub 2018 Sep 21.

Norton Neuroscience Institute, Norton Healthcare, Louisville, Kentucky, USA. Electronic address:

Background: Idiopathic intracranial hypertension (IIH) is characterized by increased intracranial pressure. IIH causes significant morbidity marked by incapacitating headaches and visual disturbances. This study investigated the long-term outcomes of venous sinus stenting in a large group of patients with IIH. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.09.070DOI Listing
January 2019
2 Reads
2.420 Impact Factor

The role of lumboperitoneal shunts in managing chronic hydrocephalus with slit ventricles.

J Neurosurg Pediatr 2018 Dec;22(6):632-637

1Departments of Neurosurgery and Pediatric Neurosurgery, Wayne State University School of Medicine and Children's Hospital of Michigan, Detroit; and.

OBJECTIVELumboperitoneal (LP) shunts have a role not only in pseudotumor cerebri, but also in patients with slit-like ventricles who are treated with CSF shunting on a chronic basis. Hesitation to utilize LP shunts is based on previous conventional beliefs including the tendency for overdrainage, difficulties accessing the shunt to tap or revise, and risk of progressive cerebellar tonsillar herniation. The authors hypothesized that the use of horizontal-vertical (HV) valves may reduce the risk of these complications, particularly overdrainage and development of Chiari malformation. Read More

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http://dx.doi.org/10.3171/2018.6.PEDS17642DOI Listing
December 2018
6 Reads
1.370 Impact Factor

Dural venous sinus stenting for idiopathic intracranial hypertension: An updated review.

J Neuroradiol 2018 Sep 13. Epub 2018 Sep 13.

Department of Neuro Interventional Surgery, Christiana Care Hospital, Newark, Delaware, USA. Electronic address:

Background: Dural venous sinus stenting (DVSS) is an accepted treatment option in selected patients with medically refractory idiopathic intracranial hypertension and obstructive venous outflow physiology prior to cerebrospinal flow diversion (CSFD) surgery. There are no randomized controlled studies focusing on outcomes and complication rates for dural venous sinus stenting.

Purpose: We present the largest comprehensive meta-analysis on DVSS for idiopathic intracranial hypertension (IIH) focusing on success rates, complications, and re-stenting rates to date. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01509861183020
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http://dx.doi.org/10.1016/j.neurad.2018.09.001DOI Listing
September 2018
3 Reads

Dural Arteriovenous Fistula Formation Complicated Cerebral Venous Sinus Stenosis After Venous Sinus Stenting.

World Neurosurg 2018 Dec 8;120:400-402. Epub 2018 Sep 8.

Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China. Electronic address:

Background: Venous stenting has become a promising treatment for venous sinus stenosis. However, it is not without its own set of risks.

Case Description: We reported de novo formation of dural arteriovenous fistula poststenting for venous sinus stenosis in a patient with pseudotumor cerebri. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.08.230DOI Listing
December 2018
3 Reads

An update of idiopathic intracranial hypertension.

Curr Opin Ophthalmol 2018 Nov;29(6):495-502

Department of Neuro-ophthalmology, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, USA.

Purpose Of Review: We aim to provide a comprehensive and updated review on idiopathic intracranial hypertension (IIH), including the most current studies and treatment options. Special focus will be put on recent theories about the pathophysiology, and on newer prospective studies on treatment modalities.

Recent Findings: The Idiopathic Intracranial Hypertension Treatment Trial (IIHTT) provided evidence supporting acetazolamide as a well tolerated first-line therapy in IIH patients with mild vision loss. Read More

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http://dx.doi.org/10.1097/ICU.0000000000000518DOI Listing
November 2018
17 Reads

Wall-eyed Bilateral Internuclear Ophthalmoplegia (WEBINO) in a Patient With Idiopathic Intracranial Hypertension.

Neurologist 2018 Sep;23(5):157-159

Neurology, AZ Maria Middelares.

Introduction: Wall-eyed bilateral internuclear ophthalmoplegia (WEBINO) is a variant syndrome of internuclear ophthalmoplegia, consisting of primary gaze exotropia, adduction impairment, nystagmus of the abducting eye, and vertical gaze-evoked nystagmus. It seems to be most frequently associated with multiple sclerosis, although other etiologies such as brainstem ischemia or hydrocephalus have also been described.

Case Report: We report the case of a 25-year-old woman who presented with subacute progressive oculomotor disturbances, resulting in the development of a WEBINO over a few days. Read More

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http://dx.doi.org/10.1097/NRL.0000000000000192DOI Listing
September 2018
16 Reads

Acute aseptic meningitis during isotretinoin treatment for nodular acne solely presenting with headache: case report and brief review of the literature.

Int J Neurosci 2018 Oct 31:1-3. Epub 2018 Oct 31.

c Department of Neurology , "Saint Andrew's" State General Hospital of Patras , Patras , Greece.

Purpose/aim: We describe, in detail, the first case of isotretinoin-induced aseptic meningitis. A brief summary of the literature on drug-induced aseptic meningitis (DIAM) is also presented.

Materials And Methods: A 20-year old female patient with probable (Naranjo adverse reaction probability score of 7) DIAM during treatment with isotretinoin therapy for nodular acne solely, presenting with headache. Read More

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https://www.tandfonline.com/doi/full/10.1080/00207454.2018.1
Publisher Site
http://dx.doi.org/10.1080/00207454.2018.1517763DOI Listing
October 2018
18 Reads

Headache Characteristics in Children With Pseudotumor Cerebri Syndrome, Elevated Opening Pressure Without Papilledema, and Normal Opening Pressure: A Retrospective Cohort Study.

Headache 2018 Oct 23;58(9):1339-1346. Epub 2018 Aug 23.

Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

Background: Certain headache characteristics and associated symptoms are commonly attributed to increased intracranial pressure, but they have not been systematically studied among children in the context of revised diagnostic criteria for pseudotumor cerebri syndrome (PTCS).

Methods: We performed a retrospective cohort study of patients treated for suspected or confirmed PTCS. Charts were reviewed for PTCS and headache diagnostic criteria and associated characteristics. Read More

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http://dx.doi.org/10.1111/head.13362DOI Listing
October 2018
3 Reads

Diffusion tensor imaging of the optic disc in idiopathic intracranial hypertension.

Neuroradiology 2018 Nov 22;60(11):1159-1166. Epub 2018 Aug 22.

Department of Ophthalmology, Mansoura Faculty of Medicine, Mansoura, Egypt.

Purpose: To study optic disc in idiopathic intracranial hypertension (IIH) with diffusion tensor imaging.

Methods: Prospective study was carried out on 31 consecutive patients with IIH and 17 age and sex-matched controls that underwent diffusion tensor imaging of optic nerve. Fractional anisotropy (FA) and mean diffusivity (MD) of optic disc were measured by two readers. Read More

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http://link.springer.com/10.1007/s00234-018-2078-1
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http://dx.doi.org/10.1007/s00234-018-2078-1DOI Listing
November 2018
17 Reads
1 Citation
2.485 Impact Factor

Successful management of peripapillary choroidal neovascular membrane secondary to idiopathic intracranial hypertension with intravitreal ranibizumab.

Indian J Ophthalmol 2018 09;66(9):1358-1360

Advanced Eye Centre, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Idiopathic intracranial hypertension (IIH) is a common cause of papilledema in young females and causes headache with transient visual loss. Severe visual loss occurs due to optic atrophy or peripapillary choroidal neovascular membrane (PCNVM). PCNVM in IIH has an incidence of 0. Read More

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http://dx.doi.org/10.4103/ijo.IJO_419_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113833PMC
September 2018
3 Reads

Pseudotumor cerebri comorbid with meningioma: A review and case series.

Surg Neurol Int 2018 4;9:130. Epub 2018 Jul 4.

Department of Neurosurgery, Hospital of the University of Pennsylvania, Philadelphia, USA.

Background: Pseudotumor cerebri (PTC), which has a prevalence in the general population of 1 to 2 out of 100,000, presents with raised intracranial pressure (ICP) but generally lacks a space occupying lesion.

Case Description: Patient 1 is a 32-year-old woman with a history of multiple meningiomas. Upon presentation to our institution, her clinical exam was notable for a right sixth nerve palsy. Read More

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http://dx.doi.org/10.4103/sni.sni_484_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044140PMC
July 2018
21 Reads

Methotrexate-induced pseudotumor cerebri in a patient with juvenile idiopathic arthritis.

Acta Neurol Belg 2018 Aug 6. Epub 2018 Aug 6.

Division of Pediatric Neurology, Cukurova University Faculty of Medicine, Toros mah. 78186 sok., Yeşilpark Evleri, Kat: 7, no: 13, Adana, Turkey.

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http://dx.doi.org/10.1007/s13760-018-0979-8DOI Listing
August 2018
2 Reads

Idiopathic Intracranial Hypertension Associated with Symptomatic Perineural Cysts: Presentation of 2 Cases.

World Neurosurg 2018 Nov 31;119:17-19. Epub 2018 Jul 31.

Department of Neurology and Neurosurgery, Federal University of São Paulo, São Paulo, Brazil.

Objectives: Idiopathic intracranial hypertension refers to cases of intracranial hypertension and normal brain parenchyma without ventriculomegaly or any kind of mass lesion. Perineural cysts are cerebrospinal fluid-filled cysts that usually arise from nerve roots near the dorsal ganglia. Often asymptomatic, they rarely cause mass effect symptoms. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S18788750183167
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http://dx.doi.org/10.1016/j.wneu.2018.07.198DOI Listing
November 2018
10 Reads

Headaches Due to Low and High Intracranial Pressure.

Continuum (Minneap Minn) 2018 Aug;24(4, Headache):1066-1091

Purpose Of Review: Headache disorders attributed to low and high intracranial pressure are commonly encountered in specialty headache practices and may occur more frequently than realized. While the headaches resulting from intracranial pressure disorders have what are conventionally thought of as defining characteristics, a substantial minority of patients do not manifest the "typical" features. Moreover, patients with intracranial pressure disorders may also have a preexisting primary headache disorder. Read More

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http://dx.doi.org/10.1212/CON.0000000000000623DOI Listing
August 2018
2 Reads

Nuances of Endovascular Treatment of Transverse/Sigmoid Sinus Stenosis With Stenting Venoplasty in a Patient With Pseudotumor Cerebri: 2-Dimensional Operative Video.

Oper Neurosurg (Hagerstown) 2019 Mar;16(3):393-394

Department of Neurosurgery, Jacobs School of Medicine and Biomedical Sciences at University at Buffalo, Buffalo, New York.

We present a case of a patient with pseudotumor cerebri (PC) and transverse/sigmoid junction sinus (TSJS) stenosis treated with stenting venoplasty. A 54-yr-old man with a history of hypertension, hyperlipidemia, and chronic obstructive pulmonary disease presented with subacute onset of progressive headaches, blurred vision, and papilledema. He was clinically diagnosed with PC. Read More

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http://dx.doi.org/10.1093/ons/opy174DOI Listing
March 2019
8 Reads

Spinal fluid evacuation may provide temporary relief for patients with unexplained widespread pain and fibromyalgia.

Med Hypotheses 2018 Sep 20;118:55-58. Epub 2018 Jun 20.

Clinical Electromyography Laboratory, University Hospitals UZ Leuven, Herestraat 49, 3000 Leuven, Belgium.

Fibromyalgia (FM) exhibits characteristics of a neurological disorder, and similarities have been identified between FM and idiopathic intracranial hypertension (IICH). When intracranial pressure rises, the drainage of excess cerebrospinal fluid (CSF) through the subarachnoid space of the cranial and spinal nerves increases. Higher CSF pressure irritates nerve fibers inside nerve root sheaths and may consequently cause radicular pain, as was reported in patients with IICH. Read More

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http://dx.doi.org/10.1016/j.mehy.2018.06.017DOI Listing
September 2018
3 Reads

Pseudotumor Cerebri Following Nexplanon® Implantation.

Cureus 2018 May 18;10(5):e2648. Epub 2018 May 18.

Department of Obstetrics and Gynecology, Quillen College of Medicine, East Tennessee State University, Johnson City, USA.

There has been much discussion about the relationship between hormonal contraceptives and the development of pseudotumor cerebri (PTC). Some have claimed that progestin-containing contraceptives, such as levonorgestrel intrauterine devices, are linked to PTC. However, the relationship and mechanism of PTC following the use of progestin-containing contraceptives remain controversial. Read More

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http://dx.doi.org/10.7759/cureus.2648DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6051559PMC
May 2018
1 Read

Recommendations for the selection and treatment of patients with idiopathic intracranial hypertension for venous sinus stenting.

J Neurointerv Surg 2018 Dec 20;10(12):1203-1208. Epub 2018 Jul 20.

Department of Neurosurgery, Rush Medical College, Chicago, Illinois, USA.

Introduction: Although venous sinus stenting (VSS) has emerged as a promising treatment option for patients with idiopathic intracranial hypertension (IIH) and associated venous sinus stenosis, there is considerable ambiguity regarding patient selection criteria, treatment protocols, and management strategies.

Methods: An extensive literature review was performed to identify all reports of VSS in patients with IIH using PubMed. Recommendations for the selection and treatment of patients with IIH with VSS are outlined as determined based on author opinion from supporting studies. Read More

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http://jnis.bmj.com/lookup/doi/10.1136/neurintsurg-2018-0140
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http://dx.doi.org/10.1136/neurintsurg-2018-014042DOI Listing
December 2018
8 Reads

Idiopathic intracranial hypertension without headache: A case report and literature review.

Agri 2018 Jul;30(3):142-145

Department of Neurology, Dışkapı Yıldırım Beyazıt Training and Research Hospital, Ankara, Turkey.

This study reports the case of a 23-year-old man with idiopathic intracranial hypertension (IIH) who presented with blurred vision and diplopia, without accompanying headache. Although headache is the most common symptom associated with IIH, occasionally, it may not be observed clinically. This situation is more frequently observed in males, young adults, children, and in patients with low body mass index. Read More

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http://dx.doi.org/10.5505/agri.2017.70370DOI Listing
July 2018
15 Reads

Trigeminal Hyperexcitability in Idiopathic Intracranial Hypertension: A Blink Reflex Study.

J Clin Neurophysiol 2018 Sep;35(5):408-414

Departments of Neurology and Clinical Neurophysiology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey.

Purpose: To compare blink reflex examination findings in patients with idiopathic intracranial hypertension (IIH) with migraineurs and controls and to investigate the role of blink reflex data in the follow-up by evaluating their relationship with clinical symptoms.

Methods: We included 23 patients with IIH, 15 migraineurs, and 16 controls. Blink reflex was studied with bilateral paired stimulations, and the 2R2/1R2 and 2R2c/1R2c area ratios, 1R2, 2R2, 1R2c, and 2R2c latencies were compared (R2:ipsilateral R2 response, R2c:contralateral R2 response). Read More

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http://dx.doi.org/10.1097/WNP.0000000000000497DOI Listing
September 2018
7 Reads

Valsalva-triggered pseudotumor cerebri syndrome: Case series and pathogenetic implications.

Neurology 2018 Aug 18;91(8):e746-e750. Epub 2018 Jul 18.

From the Departments of Clinical Neurological Sciences (T.L.H.C., D.D.K., JA.F.), Medical Imaging (M.S., D.H.L.), and Ophthalmology (J.A.F.), Western University, London, ON, Canada.

Objective: To report the clinical and radiologic features of 3 patients in whom prolonged vigorous coughing/Valsalva triggered the development of pseudotumor cerebri syndrome (PTCS) that persisted even after the coughing attacks had stopped and to discuss how this novel proximate trigger supports a "hydraulic model" of PTCS pathogenesis.

Methods: This was a retrospective case series of 3 patients seen between January 2011 and July 2017 in a tertiary care neuro-ophthalmology clinic.

Results: Three female patients (ages 13, 28, and 21 years) were asymptomatic until developing prolonged fits of profuse coughing. Read More

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http://dx.doi.org/10.1212/WNL.0000000000006048DOI Listing
August 2018
10 Reads