4,141 results match your criteria Pseudotumor Cerebri


The Use of Endoscopic Third Ventriculostomy as Treatment for Idiopathic Intracranial Hypertension: Case Report and a Review of Previously Reported Cases.

World Neurosurg 2020 Jul 4. Epub 2020 Jul 4.

Department of Neurological Surgery, University of Miami (MD).

Background: Idiopathic intracranial hypertension (IIH), or pseudotumor cerebri (PTC), is a rare disorder marked by the increase of CSF pressure that may cause severe headaches, papilledema, vision loss, and more. IIH is typically treated with shunts, but shunts are prone to malfunction and infection, resulting in many patients experiencing recurrent headaches post-treatment.

Case Description: We present the case of a 41-year-old woman with IIH who exhibited a history of severe headaches and seizures with documented elevated intracranial pressure (OP: 250 mm HO). Read More

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http://dx.doi.org/10.1016/j.wneu.2020.06.088DOI Listing

Pseudotumor Cerebri Syndrome in Young Children: What Is the Difference From Adults?

J Child Neurol 2020 Jul 7:883073820935727. Epub 2020 Jul 7.

Child Neurology and Development Center, Hillel-Yaffe Medical Center, Hadera, Israel.

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http://dx.doi.org/10.1177/0883073820935727DOI Listing

Pseudotumor Cerebri in Young Children: Is It Different From Adults?

J Child Neurol 2020 Jun 29:883073820935720. Epub 2020 Jun 29.

Pediatric Neurology Unit, Department of Pediatrics, Advanced Pediatrics Centre, Post Graduate Institute of Medical Education & Research (PGIMER), Chandigarh, India.

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http://dx.doi.org/10.1177/0883073820935720DOI Listing

Innominate vein stenosis causing raised intracranial pressure and blindness.

J Vasc Surg Cases Innov Tech 2020 Jun 6;6(2):282-284. Epub 2020 Jun 6.

UNC Rex Hospital, Raleigh, NC.

Central venous stenosis causing elevated intracranial pressure is a rare and potentially reversible cause of blindness in patients undergoing hemodialysis. We present the case of a 69-year-old man with progressive vision loss and raised intracranial pressure that was successfully treated with an innominate vein stent. Read More

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http://dx.doi.org/10.1016/j.jvscit.2018.04.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7283974PMC

COVID-19 and benign intracranial hypertension: A case report.

Rev Soc Bras Med Trop 2020 8;53:e20200325. Epub 2020 Jun 8.

Universidade Federal do Rio de Janeiro, Departamento de Radiologia, Rio de Janeiro, RJ, Brasil.

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http://dx.doi.org/10.1590/0037-8682-0325-2020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294953PMC

Lumbo-peritoneal shunt as treatment modality for visual symptoms in idiopathic intracranial hypertension: A single institution experience.

Neurocirugia (Astur) 2020 May 29. Epub 2020 May 29.

Post Graduate Institute of Neurological Surgery, Dr. Achanta Lakshmipathi Neurosurgical Centre, Voluntary Health Services Multi-speciality Hospital & Research Centre, TTTI Post, Taramani, Chennai 600113, Tamil Nadu, India.

Objectives: To evaluate the efficacy of lumbo-peritoneal shunt (LPS) in patients of idiopathic intracranial hypertension presenting with visual symptoms.

Methods: Between Apr. 2014 and Mar. Read More

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http://dx.doi.org/10.1016/j.neucir.2020.03.001DOI Listing

Effect of Shunting on Visual Outcomes and Headache in Patients with Idiopathic Intracranial Hypertension.

World Neurosurg 2020 May 28. Epub 2020 May 28.

Department of Neurosurgery, Thomas Jefferson University and Jefferson Hospital forNeuroscience, Philadelphia, Pennsylvania, USA. Electronic address:

Background: Visual dysfunction and headache are major symptoms in patients with idiopathic intracranial hypertension (IIH).

Objective: We aim to evaluate the improvement of these symptoms in patients who underwent ventriculoperitoneal (VPS) and lumboperitoneal (LPS) shunting.

Methods: Electronic medical records were reviewed to identify baseline and treatment characteristics for patients diagnosed with IIH over ten years. Read More

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http://dx.doi.org/10.1016/j.wneu.2020.05.186DOI Listing
May 2020
2.417 Impact Factor

An update on idiopathic intracranial hypertension in adults: a look at pathophysiology, diagnostic approach and management.

J Neurol 2020 May 27. Epub 2020 May 27.

Department "GF Ingrassia", Section of Neurosciences, University of Catania, Via Santa Sofia 78, 95123, Catania, Italy.

Idiopathic intracranial hypertension is a neurological syndrome determined by a rise in intracranial pressure without a detectable cause. Course and prognosis may be changeable, requiring a multidisciplinary approach for its diagnosis and management. Although its precise pathogenesis is still unknown, many studies have been carried out to define the possible causal and associated factors, such as retinoids, steroid hormones, body mass index and recent weight gains, cytokines and adipokines levels. Read More

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http://dx.doi.org/10.1007/s00415-020-09943-9DOI Listing

Infectious and inflammatory disorders might increase the risk of developing idiopathic intracranial hypertension - a national case-control study.

Cephalalgia 2020 May 25:333102420928079. Epub 2020 May 25.

Department of Clinical Neuroscience, Karolinska Institutet and Department of Neurology, Karolinska University Hospital, Sweden.

Objective: To investigate whether conditions causing inflammatory activation are associated with increased risk of idiopathic intracranial hypertension.

Methods: All newly diagnosed idiopathic intracranial hypertension patients (cases) in Sweden between 2000-2016 were identified using pre-determined algorithms (n = 902) and matched with five controls from the general population and five individuals with an obesity diagnosis (n = 4510) for age, sex, region, and vital status. National health registers provided information on infections, inflammatory disorders and dispensed medications. Read More

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http://dx.doi.org/10.1177/0333102420928079DOI Listing

Update in Pediatric Pseudotumor Cerebri Syndrome.

Authors:
Shannon J Beres

Semin Neurol 2020 Jun 18;40(3):286-293. Epub 2020 May 18.

Department of Neurology and Ophthalmology, Stanford University, Palo Alto, California.

Pseudotumor cerebri syndrome (PTCS) is a rare condition in children presenting with headache and papilledema from increased intracranial pressure that can cause significant morbidity. This can be idiopathic, also known as idiopathic intracranial hypertension or primary intracranial hypertension, or can be secondary to medications and associated medical conditions. Given the threat to vision, early detection and treatment is needed in all age groups. Read More

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http://dx.doi.org/10.1055/s-0040-1708847DOI Listing

Idiopathic Intracranial Hypertension: Contemporary Management and Endovascular Techniques.

Semin Intervent Radiol 2020 Jun 14;37(2):175-181. Epub 2020 May 14.

Department of Radiology, University of Colorado School of Medicine, Aurora, Colorado.

Idiopathic intracranial hypertension (IIH) is a disease process of abnormally increased intracranial pressure in the absence of a mass lesion. Medical management, optic nerve fenestration, and surgical shunting procedures have failed to produce consistently successful results. In an unknown percentage of cases, IIH is caused by dural venous sinus obstruction which can be cured by endovascular treatment with dural venous sinus stent placement. Read More

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http://dx.doi.org/10.1055/s-0040-1709172DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7224981PMC

Neuroangiography: Review of Anatomy, Periprocedural Management, Technique, and Tips.

Semin Intervent Radiol 2020 Jun 14;37(2):166-174. Epub 2020 May 14.

Department of Neurosurgery, University of Colorado School of Medicine, Aurora, Colorado.

Neuroangiography (NA) is a minimally invasive procedure used to diagnose patients with neurovascular diseases. Noninvasive imaging has improved dramatically in recent years and is utilized more frequently; however, further evaluation with NA is still required in certain cases. NA indications include intracranial (cerebral aneurysms, arteriovenous malformations, dural arteriovenous fistula, cerebral vasculitis, cerebral vasospasm, ischemic stroke, nontraumatic subarachnoid hemorrhage, intracerebral hemorrhage, Moyamoya, vein of Galen malformation, intracranial tumors, and pseudotumor cerebri) and extracranial (internal and common carotid artery stenosis, vertebral artery stenosis, carotid artery blowout, vertebral artery blowout, epistaxis, oropharyngeal bleeding, and carotid body tumor) pathologies which can help with diagnosis and potential subsequent endovascular treatment. Read More

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http://dx.doi.org/10.1055/s-0040-1709171DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7224980PMC

Optical coherence tomography use in idiopathic intracranial hypertension.

Ann Eye Sci 2020 Mar 15;5. Epub 2020 Mar 15.

Department of Ophthalmology, Stanford University, Palo Alto, CA, USA.

Idiopathic intracranial hypertension (IIH) is a condition in which elevated pressure in the cerebrospinal fluid can lead to optic nerve head (ONH) dysfunction and subsequent visual impairment. Physicians are currently limited in their ability to monitor and manage this condition, as clinical symptoms and exam findings are often delayed in response to changes in intracranial pressure. In order to find other biomarkers of disease, researchers are using imaging modalities such as optical coherence tomography (OCT) to observe microscopic changes in the eye in this condition. Read More

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http://dx.doi.org/10.21037/aes.2019.12.06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7220123PMC

Assessment of the optic nerve using strain and shear-wave elastography in patients with pseudotumour cerebri.

Clin Radiol 2020 May 4. Epub 2020 May 4.

Department of Neurology, Kirikkale University School of Medicine, Kirikkale, Turkey.

Aim: To evaluate the optic nerve using strain elastography (SE) and shear-wave elastography (SWE) in idiopathic intracranial hypertension (IIH) patients in comparison to participants in the control group.

Materials And Methods: Eighty eyes were evaluated in 40 cases consisting of 20 IIH patients and 20 participants in the control group. This study was conducted using SE and SWE in addition optic nerve sonography measurements of participants in the IIH patient group and the control group. Read More

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http://dx.doi.org/10.1016/j.crad.2020.03.038DOI Listing

Styloidogenic jugular venous compression syndrome: a case report and review of the literature.

Childs Nerv Syst 2020 Apr 28. Epub 2020 Apr 28.

Department of Neurosurgery, University of Alabama at Birmingham, 1802 6th Avenue South, FOT 1001, Birmingham, AL, 35233, USA.

Background: Styloidogenic jugular venous compression syndrome (SJVCS) has been shown to present with a similar symptomatology to idiopathic intracranial hypertension (IIH) and is caused by compression of the internal jugular vein (IJV) between the lateral tubercle of C1 and the styloid process. Treatments including venous stenting and styloidectomy have been reported with good outcomes; however, treatment of a pediatric patient with SJVCS with styloidectomy has not previously been reported in the literature.

Case Report: A 12-year-old male presented with refractory positional headaches, nausea, and vomiting, and after, workup including lumbar puncture (LP) and intracranial pressure (ICP) monitoring was found to have intracranial hypertension associated with contralateral neck turning. Read More

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http://dx.doi.org/10.1007/s00381-020-04622-6DOI Listing

A systematic review of surgical treatments of idiopathic intracranial hypertension (IIH).

Neurosurg Rev 2020 Apr 25. Epub 2020 Apr 25.

Department of Neurological Surgery, New York Presbyterian Hospital/Weill Cornell Medical Center, New York, NY, USA.

Idiopathic intracranial hypertension denotes raised intracranial pressure in the absence of an identifiable cause and presents with symptoms relating to elevated ICP, namely headaches and visual deterioration. Treatment of IIH aims at reducing intracranial pressure, relieving headache and salvaging patients' vision. Surgical interventions are recommended for medically refractory IIH and include CSF diversion techniques, optic nerve sheath fenestration, bariatric surgery and venous sinus stenting. Read More

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http://dx.doi.org/10.1007/s10143-020-01288-1DOI Listing

Fulminant Idiopathic Intracranial Hypertension.

Authors:
Marc A Bouffard

Curr Neurol Neurosci Rep 2020 Mar 26;20(4). Epub 2020 Mar 26.

Department of Neurology, Division of Neuro-Ophthalmology, Beth Israel Deaconess Medical Center, Harvard Medical School, Shapiro Building, 5th Floor, 330 Brookline Avenue, Boston, MA, 02215, USA.

Purpose Of Review: The goal of this review is to describe the presenting features of fulminant idiopathic intracranial hypertension (IIH) and outline the multimodal approach to its treatment.

Recent Findings: Venous sinus stenting may be an appropriate alternative to optic nerve sheath fenestration or cerebrospinal fluid shunting in select patients with fulminant IIH. Prompt surgical intervention maximizes the chance of visual recovery in patients with fulminant IIH. Read More

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http://dx.doi.org/10.1007/s11910-020-1026-8DOI Listing

Sleep Disturbance in Pediatric Intracranial Hypertension.

J Clin Sleep Med 2020 Mar 24. Epub 2020 Mar 24.

Department of Neurology and Sleep Medicine, Nationwide Children's Hospital, Columbus, Ohio.

Study Objectives: There is a well-established association between headache disorders and sleep disturbances in children, but it is unknown if sleep disturbance plays a role in pediatric intracranial hypertension. The objective of this study was to examine sleep issues related to pediatric intracranial hypertension.

Methods: Patients with intracranial hypertension who were followed in the Pediatric Intracranial Hypertension Clinic were recruited between July 2017 and September 2018. Read More

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http://dx.doi.org/10.5664/jcsm.8436DOI Listing

Sleep Disturbance in Pediatric Intracranial Hypertension.

J Clin Sleep Med 2020 Mar 24. Epub 2020 Mar 24.

Department of Neurology and Sleep Medicine, Nationwide Children's Hospital, Columbus, Ohio.

Study Objectives: There is a well-established association between headache disorders and sleep disturbances in children, but it is unknown if sleep disturbance plays a role in pediatric intracranial hypertension. The objective of this study was to examine sleep issues related to pediatric intracranial hypertension.

Methods: Patients with intracranial hypertension who were followed in the Pediatric Intracranial Hypertension Clinic were recruited between July 2017 and September 2018. Read More

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http://dx.doi.org/jc-19-00636DOI Listing

Idiopathic Intracranial Hypertension: The Monster Within.

Ann Indian Acad Neurol 2020 Mar-Apr;23(2):159-166. Epub 2020 Feb 25.

Department of Neurology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

Idiopathic intracranial hypertension (IIH) is defined as a syndrome of raised intracranial pressure with normal imaging of the brain and cerebrospinal fluid (CSF) composition. There are many controversies and myths that surround IIH. Although patients of IIH may present "typical" symptoms and signs of raised intracranial pressure, clinical scenarios often vary. Read More

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http://dx.doi.org/10.4103/aian.AIAN_190_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7061511PMC
February 2020

C1 Transverse Process Resection for Management of Jugular Stenosis.

Oper Neurosurg (Hagerstown) 2020 Mar 17. Epub 2020 Mar 17.

Department of Neurosurgery, University of New Mexico, Albuquerque, New Mexico.

Background And Importance: Idiopathic intracranial hypertension, also known as pseudotumor cerebri, often presents with severe headache and associated vision loss. Venous outflow obstruction has been noted as a prominent etiologic factor in many cases, and previous anatomic studies have shown that the internal jugular (IJ) vein at the skull base can be prone to compression by the neighboring bony structures.

Clinical Presentation: We present a case of 13-yr-old male with a multifactorial intracranial hypertension including compression of the IJ vein by the transverse process of C1. Read More

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http://dx.doi.org/10.1093/ons/opaa032DOI Listing

Coexistence of papilledema and pseudopapilledema after remission of idiopathic intracranial hypertension by bariatric surgery.

Arq Bras Oftalmol 2020 Mar-Apr;83(2):157-159

Instituto de Olhos, Faculdade de Ciências Médicas de Minas Gerais, Belo Horizonte, MG, Brazil.

A 37-year-old woman complained of headaches following bilateral visual loss in the past two years. She was obese and had undergone bariatric surgery three months earlier, followed by a considerable weight loss. Neuro-ophthalmic examination revealed a bilateral swollen optic disk. Read More

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http://dx.doi.org/10.5935/0004-2749.20200030DOI Listing

Myelin oligodendrocyte glycoprotein antibody-associated optic neuritis mimicking pseudotumor cerebri: A case report.

Rev Neurol (Paris) 2020 Mar 5. Epub 2020 Mar 5.

Service de neurologie, sclérose en plaques, pathologies de la myéline et neuro-inflammation; C2RC-SEP de Lyon; Centre des Maladies Rares Inflammatoires du Cerveau et de la Moelle, Hôpital Neurologique Pierre Wertheimer, Hospices civils de Lyon, 69677 Lyon-Bron, France.

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http://dx.doi.org/10.1016/j.neurol.2020.01.357DOI Listing

Letter to the Editor Regarding "Reliability of Outpatient Telemetric Intracranial Pressure Measurements in Shunt-Dependent Patients; Common Mistake in Reliability Analysis".

World Neurosurg 2020 03;135:385-386

Department of Clinical Epidemiology, School of Health and Safety, Shahid Beheshti University of Medical Sciences, Tehran, I.R. Iran.

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http://dx.doi.org/10.1016/j.wneu.2019.11.061DOI Listing

Is Magnetic Resonance Imaging Diffusion Restriction of the Optic Disc Head a New Marker for Idiopathic Intracranial Hypertension?

J Neurosci Rural Pract 2020 Jan 27;11(1):170-174. Epub 2019 Dec 27.

Department of Neurology, University of Missouri, Columbia, Missouri, United States.

Idiopathic intracranial hypertension (IIH) is a headache syndrome due to raised intracranial pressure of unknown etiology. Before making the diagnosis of IIH, secondary causes of raised intracranial pressure must be ruled out. The radiological features associated with this condition have variable sensitivity and specificity. Read More

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http://dx.doi.org/10.1055/s-0039-3402621DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7055610PMC
January 2020

Correlation between the total number of features of paediatric pseudotumour cerebri syndrome and cerebrospinal fluid pressure.

Childs Nerv Syst 2020 Mar 2. Epub 2020 Mar 2.

Paediatric Neurology, Department of Paediatrics, Cambridge University Hospitals NHS Foundation Trust, Hills Road, Cambridge, CB2 0QQ, UK.

Purpose: Accurate diagnosis of pseudotumour cerebri syndrome (PTCS) in children is challenging. We aimed to see if the clinical and radiological assessment that is carried out before lumbar puncture could predict subsequently recorded CSF pressures, and thus whether it could be used to increase diagnostic certainty of paediatric PTCS.

Methods: We used internationally recognised diagnostic criteria to derive a list of clinical, brain neuroimaging and venography features that were accepted to be associated with a diagnosis of PTCS. Read More

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http://dx.doi.org/10.1007/s00381-020-04537-2DOI Listing

Lumbar puncture rapidly improves olfaction in patients with idiopathic intracranial hypertension: A cohort study.

Cephalalgia 2020 Apr 23;40(5):429-436. Epub 2020 Feb 23.

Department of Psychology, Faculty of Natural Sciences, MSB Medical School Berlin, Berlin, Germany.

Background: A lumbar puncture constitutes an important diagnostic procedure in the evaluation of idiopathic intracranial hypertension. Chronic overflow of cerebrospinal fluid into the sheaths of the olfactory nerves appears to be related to olfactory impairment in these patients. Here, we asked whether cerebrospinal fluid drainage in idiopathic intracranial hypertension patients improves olfactory function. Read More

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http://dx.doi.org/10.1177/0333102420908875DOI Listing

Shunt infusion studies: impact on patient outcome, including health economics.

Acta Neurochir (Wien) 2020 05 20;162(5):1019-1031. Epub 2020 Feb 20.

Department of Clinical Neurosciences, Division of Neurosurgery, Cambridge University Hospital NHS Foundation Trust, Cambridge, UK.

Objectives: The diagnosis of shunt malfunction is often not straightforward. We have explored, in symptomatic shunted patients with hydrocephalus or pseudotumour cerebri syndrome (PTCS), the accuracy of CSF infusion tests in differentiating a functioning shunt from one with possible problems, and the health economic consequences.

Methods: Participants: hydrocephalus/PTCS patients with infusion tests performed from January 2013 until December 2015. Read More

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http://dx.doi.org/10.1007/s00701-020-04212-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156359PMC

Clinical performance of fixed-pressure Sphera Duo® hydrocephalus shunt.

Arq Neuropsiquiatr 2020 01;78(1):9-12

Universidade de São Paulo, Hospital das Clínicas, Instituto de Psiquiatria, Divisão de Neurocirurgia Funcional, Grupo de Hidrodinâmica Cerebral, São Paulo SP, Brazil.

Introduction: Cerebral hydrodynamics complications in shunted patients are due to the malfunction of the system. The objective of this retrospective, single-center, single-arm cohort study is to confirm the safety and performance of Sphera® Duo when used in adult patients suffering from hydrocephalus, pseudotumor cerebri or arachnoid cysts.

Methods: Data were generated by reviewing 112 adult patient's charts, who were submitted to a ventriculoperitoneal shunt surgery and followed for one year after surgery. Read More

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http://dx.doi.org/10.1590/0004-282X20190135DOI Listing
January 2020

Neurenteric cyst secondary to lumboperitoneal shunt.

Surg Neurol Int 2020 24;11:14. Epub 2020 Jan 24.

Department of Biochemistry and Medical Genetics, University of Manitoba, Winnipeg, Manitoba.

Background: Neurenteric cysts are rare lesions that typically present in the upper thoracic and cervical spine and are occasionally found intracranially. The optimal treatment is gross total excision as subtotal/partial excisions are associated with high recurrence rates.

Case Description: For the past 10 years, a patient with pseudotumor cerebri required repeated lumboperitoneal (LP) shunt revisions. Read More

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http://dx.doi.org/10.25259/SNI_589_2019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7006444PMC
January 2020

Coprescription of Isotretinoin and Tetracyclines for Acne is Rare: An Analysis of the National Ambulatory Medical Care Survey.

J Clin Aesthet Dermatol 2019 Oct 1;12(10):45-48. Epub 2019 Oct 1.

Drs. Reserva, Vasicek, Tung, and Swan are with the Division of Dermatology at Loyola University Chicago in Chicago, Illinois.

Systemic therapy for acne can include tetracyclines or, for severe cases, isotretinoin. Concurrent use of tetracyclines and isotretinoin is known to increase the risk of development of pseudotumor cerebri (PTC). Given their association with PTC when used concomitantly, this study sought to quantify the estimated frequency of the coprescription of isotretinoin and tetracyclines and to assess for trends in the use of isotretinoin and tetracycline for acne as it relates to age, sex, race, insurance, and provider specialty. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6937145PMC
October 2019

Vitamin B12 Deficiency: An Association or Etiology of Pseudotumor Cerebri in An Infant.

Indian J Pediatr 2020 Feb 8. Epub 2020 Feb 8.

Pediatric Neurology Unit, Department of Pediatrics, Advanced Pediatrics Centre, Post Graduate Institute of Medical Education & Research (PGIMER), Chandigarh, 160012, India.

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http://dx.doi.org/10.1007/s12098-020-03212-3DOI Listing
February 2020
0.919 Impact Factor

Exploring The Current Management Idiopathic Intracranial Hypertension, And Understanding The Role Of Dural Venous Sinus Stenting.

Eye Brain 2020 14;12:1-13. Epub 2020 Jan 14.

Birmingham Neuro-Ophthalmology, Queen Elizabeth Hospital, University Hospitals Birmingham, Birmingham B15 2WB, UK.

Idiopathic Intracranial Hypertension (IIH) is a debilitating disorder characterised by raised intracranial pressure (ICP), papilloedema with the potential risk of permanent visual loss, and headaches that are profoundly disabling and reduce the quality of life. The first consensus guidelines have been published on investigation and management of adult IIH and one key area of uncertainty is the utility of dural venous sinus stenting for the management of headache and visual loss. There are an increasing number of series published and to help understand the successes and complications. Read More

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http://dx.doi.org/10.2147/EB.S193027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6969694PMC
January 2020

Endovascular Treatment of Cerebral Venous Sinus Stenosis Based on Hemodynamic Assessment Using Pressure Wire.

World Neurosurg 2020 Apr 28;136:323-325. Epub 2020 Jan 28.

Department of Neurology, Jinling Hospital, Medical School of Nanjing University, Nanjing, Jiangsu Province, China.

Background: A pressure wire offers a dynamic tool to assist in the measurement of the pressure gradient and assessment of the functional significance of stenosis. The author presents a patient with idiopathic intracranial hypertension who was diagnosed with cerebral venous sinus stenosis (CVSS). Venography accompanied by pressure measurement was used to guide the stent placement for CVSS. Read More

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http://dx.doi.org/10.1016/j.wneu.2020.01.128DOI Listing
April 2020
2.417 Impact Factor

A rare case of pseudotumor cerebri in adult Lyme disease.

Clin Case Rep 2020 Jan 18;8(1):116-119. Epub 2019 Dec 18.

Neurological Department Herlev Hospital Herlev Denmark.

It is important to recognize the rare manifestations of chronic Lyme disease to prevent permanent disabilities. We present an adult case of chronic Lyme disease, who developed pseudotumor cerebri and who needed supplementary surgical treatment. We compare it to the existing published literature, reviewed by a systematic approach. Read More

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http://dx.doi.org/10.1002/ccr3.2582DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6982509PMC
January 2020

Custom Shunt System for Increased Baseline Intracranial Pressure in a Patient with Idiopathic Intracranial Hypertension.

World Neurosurg 2020 Apr 26;136:318-322. Epub 2020 Jan 26.

Department of Neurosurgery, Washington University School of Medicine, St. Louis, Missouri, USA.

Background: Standard treatment of idiopathic intracranial hypertension (IIH) involves reduction of intracranial pressure (ICP) to normal range, often via a ventriculoperitoneal shunt (VPS). We describe a case of a middle-aged man who presented with symptoms consistent with IIH. After ICP was normalized with a VPS, the patient had neurologic deterioration into a coma. Read More

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http://dx.doi.org/10.1016/j.wneu.2020.01.142DOI Listing

Pseudotumour Cerebri Syndrome in China: A Cohort Study.

Sci Rep 2020 01 27;10(1):1222. Epub 2020 Jan 27.

Department of Ophthalmology, Eye Ear Nose and Throat Hospital of Fudan University, Shanghai, China.

Pseudotumour cerebri syndrome (PTCS) remains to be fully investigated in Chinese patients and our study reported PTCS-related clinical differences between Chinese patients and Western patients. This study enrolled 55 consecutive patients (females: 44, median age: 37 y, age range: 14-62 y) with PTCS diagnosed from October 2015 to December 2017. Nine (16. Read More

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http://dx.doi.org/10.1038/s41598-020-58080-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6985260PMC
January 2020
5.078 Impact Factor

Pseudotumor Cerebri Syndrome: From Childhood to Adulthood Risk Factors and Clinical Presentation.

J Child Neurol 2020 Apr 13;35(5):311-316. Epub 2020 Jan 13.

The Ruth and Bruce Rappaport Faculty of Medicine, Technion, Haifa, Israel.

Introduction: Although considered uncommon, pseudotumor cerebri syndrome (PTC) is a significant cause of headache among children and adults. However, the presenting symptoms may be different among diverse age groups. In the present study, we compared the risk factors and clinical presentation of PTC across life-from childhood to adulthood. Read More

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http://dx.doi.org/10.1177/0883073819895179DOI Listing

Evaluation of abnormal styloid anatomy as a cause of internal jugular vein compression using a 3D-printed model: a laboratory investigation.

J Clin Neurosci 2020 Feb 26;72:386-391. Epub 2019 Dec 26.

Department of Neurosurgery, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, AZ, United States. Electronic address:

This study used a 3-dimensional (3D) craniocervical junction model of styloidogenic jugular venous compression (SJVC) syndrome to simulate and evaluate intracranial pressure (ICP) after internal jugular vein (IJV) compression by an elongated styloid process during axial rotation. The 3D-printed model created using data from an SJVC-syndrome patient included an articulating occipital-cervical junction, simplified arteriovenous system, gauge to measure simulated ICP, fixed obstruction simulating left-sided venous occlusion, and right-sided vascular tubing to simulate IJV compression. The model was rotated axially to its extreme right and left; maximum degree of motion and pressure were recorded for 3 cycles. Read More

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http://dx.doi.org/10.1016/j.jocn.2019.11.048DOI Listing
February 2020

Pseudotumor cerebri in a transgender woman: case report and literature review.

Can J Ophthalmol 2020 Jun 24;55(3):e110-e112. Epub 2019 Dec 24.

Department of Ophthalmology and Visual Neurosciences, University of Minnesota, Minneapolis, MN. Electronic address:

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http://dx.doi.org/10.1016/j.jcjo.2019.09.008DOI Listing

Commentary: Assessing the lamina cribrosa in idiopathic intracranial hypertension.

Authors:
Padmaja Sudhakar

Indian J Ophthalmol 2020 01;68(1):168-169

Department of Ophthalmology and Neurology, University of Lexington, KY, USA.

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http://dx.doi.org/10.4103/ijo.IJO_1435_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6951149PMC
January 2020

Men Are from Mars, Idiopathic Intracranial Hypertension Is from Venous: The Role of Venous Sinus Stenosis and Stenting in Idiopathic Intracranial Hypertension.

Semin Neurol 2019 12 17;39(6):692-703. Epub 2019 Dec 17.

Department of Ophthalmology, Weill Cornell Medical College, New York Presbyterian Hospital, New York.

Idiopathic intracranial hypertension (IIH), also known as pseudotumor cerebri, is a disease primarily affecting obese women of child-bearing age, typically presenting with positional headaches, diplopia from abducens nerve palsies, pulse-synchronous tinnitus, and visual disturbances related to papilledema, including transient visual obscurations, blurry vision, and visual field defects. Controversy remains regarding the pathophysiology of IIH. Elevated intracranial pressure in IIH is thought to be the result of a dysregulation of cerebrospinal fluid (CSF) dynamics, through excessive secretion, reduced drainage, or both. Read More

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http://dx.doi.org/10.1055/s-0039-3399506DOI Listing
December 2019

Coupling of CSF and sagittal sinus pressure in adult patients with pseudotumour cerebri.

Acta Neurochir (Wien) 2020 05 12;162(5):1001-1009. Epub 2019 Dec 12.

Department of Radiology, Addenbrooke's Hospital, Cambridge, UK.

Objective: Pseudotumour cerebri syndrome (PTCS including idiopathic intracranial hypertension) is characterised by the symptoms and signs of raised cerebrospinal fluid pressure (CSFp) in the absence of ventricular dilatation or an intracranial mass lesion. Its aetiology is unknown in the majority of cases but there is much evidence for impaired CSF absorption. Traditionally, sagittal sinus pressure has been considered to be independent of CSF pressure in adults. Read More

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http://dx.doi.org/10.1007/s00701-019-04095-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156361PMC

Preclinical update on regulation of intracranial pressure in relation to idiopathic intracranial hypertension.

Fluids Barriers CNS 2019 Nov 26;16(1):35. Epub 2019 Nov 26.

Danish Headache Center, Department of Neurology, Glostrup Research Institute, Rigshospitalet-Glostrup, University of Copenhagen, Nordstjernevej 42, 2600, Glostrup, Denmark.

Background: Elevated intracranial pressure (ICP) is observed in association with a range of brain disorders. One of these challenging disorders is idiopathic intracranial hypertension (IIH), characterized by raised ICP of unknown cause with significant morbidity and limited therapeutic options. In this review, special focus is put on the preclinical research performed in order to understand the pathophysiology behind ICP regulation and IIH. Read More

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http://dx.doi.org/10.1186/s12987-019-0155-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6878629PMC
November 2019

[Pseudo-tumor form of neuro-Behçet disease: case study and literature review].

Pan Afr Med J 2019 12;33:194. Epub 2019 Jul 12.

Service de Neurochirurgie, CHU Mohammed VI Oujda, Oujda, Maroc.

Mass lesions of the brain are not always a tumor. We report the case of a patient followed for Behcet syndrome presenting with expansive intracranial process revealed by right hemiparesis associated with signs of intracranial hypertension. Brain magnetic resonance imaging (MRI) showed a lesion suggesting glial tumor. Read More

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http://dx.doi.org/10.11604/pamj.2019.33.194.18719DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814321PMC
November 2019
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Pediatric Acquired and Progressive Retinal Nerve Fiber Layer Myelination Following Idiopathic Intracranial Hypertension.

J Pediatr Ophthalmol Strabismus 2019 Oct 17;56:e57-e59. Epub 2019 Oct 17.

Few anecdotal reports have documented new onset and progression of myelination of the retinal nerve fiber layer. The authors report the unusual onset and progression of acquired myelination of the retinal nerve fiber layer in two children, following the diagnosis of presumed idiopathic intracranial hypertension. The nosologic relationship between myelination of the retinal nerve fiber layer and idiopathic intracranial hypertension is unclear and requires elucidation by further studies. Read More

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http://dx.doi.org/10.3928/01913913-20190805-02DOI Listing
October 2019
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The Role of Onabotulinum Toxin Type A in the Management of Chronic Non-migraine Headaches.

Front Neurol 2019 19;10:1009. Epub 2019 Sep 19.

Department of Neurology, University of Missouri School of Medicine, Columbia, MO, United States.

FDA has approved Onabotulinum toxin type A (BoNTA) for prophylactic treatment of chronic migraines. Recent studies have explored its potential new indications, like treating post-traumatic headaches. This is a retrospective chart review of 717 patients, who had failed at least two prophylactic treatments and received BoNTA injections at University of Missouri Hospital from July 2014 to June 2017. Read More

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http://dx.doi.org/10.3389/fneur.2019.01009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6763695PMC
September 2019
1 Read

Fulminant Pseudotumor Cerebri Syndrome Secondary to Over-the-Counter Topical Retinoids.

J Neuroophthalmol 2020 Jun;40(2):248-249

Neuro-Ophthalmology Service, Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts.

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http://Insights.ovid.com/crossref?an=00041327-900000000-9909
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http://dx.doi.org/10.1097/WNO.0000000000000857DOI Listing
June 2020
6 Reads

Long-Term Follow-up of Pseudotumor Cerebri Syndrome in Prepubertal Children, Adolescents, and Adults.

Pediatr Neurol 2019 12 27;101:57-63. Epub 2019 Apr 27.

Department of Ophthalmology, Kaplan Medical Center, Rehovot, Israel; The Hebrew University of Jerusalem, Jerusalem, Israel.

Purpose: Pseudotumor cerebri syndrome can have a recurrent course. We compared the long-term disease course, recurrences, and final visual outcomes in prepubertal children, adolescents, and adults.

Methods: In this retrospective observational study, patients were divided into prepubertal children (group A) adolescents (group B), and adults (group C). Read More

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http://dx.doi.org/10.1016/j.pediatrneurol.2019.04.018DOI Listing
December 2019
1 Read
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