J Neuroophthalmol 2020 Jun 19. Epub 2020 Jun 19.
Department of Ophthalmology and Visual Science (AAK), Yale University School of Medicine, New Haven, Connecticut; Department of Ophthalmology (MP), Center for Preventative Ophthalmology and Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania; Department of Ophthalmology (CA), Icahn School of Medicine at Mount Sinai, New York, New York; Scheie Eye Institute (AGR, GTL, KSS, MAT), Department of Ophthalmology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania; Department of Ophthalmology (IJ), University of Alberta, Edmonton, Canada; Department of Medicine (SB), Temple University, Philadelphia, Pennsylvania; Rutgers Robert Wood Johnson Medical School (JC), Piscataway, New Jersey; Boston University Henry M. Goldman School of Dental Medicine (DM), Boston, Massachusetts; and Department of Neurology (GTL), Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Background: We prospectively evaluated the sensitivity and specificity of ocular ultrasonography (OUS) to distinguish papilledema from pseudopapilledema.
Methods: Forty-nine study participants, with optic disc elevation, underwent neuro-ophthalmic evaluation, OUS, fundus photography, and optical coherence tomography (OCT) of the optic nerve head at the initial and follow-up visits (≤6 months apart). Participants were classified as having papilledema if there was a change in optic nerve appearance on fundus photographs, as determined by a masked observer, between initial and follow-up visits ≤6 months apart. Read More