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    400 results match your criteria Pseudolymphoma Cutaneous

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    Red tattoo-related mycosis fungoides-like CD8+ pseudolymphoma.
    J Cutan Pathol 2017 Nov 28. Epub 2017 Nov 28.
    Department of Dermatology, Mayo Clinic, Rochester, Minnesota.
    Cutaneous reactions to red tattoo pigment rarely manifest as pseudolymphomatous reactions. We describe an exceedingly rare case of red tattoo-related T-cell predominant pseudolymphoma microscopically mimicking mycosis fungoides. Careful clinicopathological correlation was required to obtain the correct diagnosis and aid in an effective treatment course. Read More

    Treatment of Cutaneous Pseudolymphoma: A Systematic Review.
    Acta Derm Venereol 2017 Nov 14. Epub 2017 Nov 14.
    Department of Dermatology, Jena University Hospital Erfurter Straße 35, DE-07743 Jena, Germany.
    Cutaneous pseudolymphoma (CPL) is a reactive polyclonal T- or B-cell lymphoproliferative process. CPL may appear as localized or disseminated skin lesions. While most cases of CPL are idiopathic, they may also occur as a response to, for example, contact dermatitis, arthropod reactions, and bacterial infections. Read More

    Eruption of lymphocyte recovery with atypical lymphocytes mimicking a primary cutaneous T-cell lymphoma: a series of 12 patients.
    Hum Pathol 2018 Jan 28;71:100-108. Epub 2017 Oct 28.
    Department of Pathology and INSERM U955 team 9, AP-HP, Henri-Mondor Hospital, 94220 Créteil, France. Electronic address:
    Eruption of lymphocyte recovery (ELR) may occur during bone marrow aplasia after chemotherapies. We reviewed the clinical and pathologic features of 12 patients (male-female ratio, 7:5; median age, 61 years) with an atypical ELR histologically mimicking a primary cutaneous T-cell lymphoma such as Sézary syndrome or CD30+ T-cell lymphoproliferative disorder. All the patients displayed an erythematous maculopapular eruption on the trunk and the limbs associated with fever. Read More

    Perianal pseudolymphoma: A case report and review of the literature.
    Int J Surg Case Rep 2017 17;39:271-272. Epub 2017 Aug 17.
    Department of Surgery, Cairns Private Hospital, Cairns, Queensland, Australia.
    Introduction: Perianal pseudolymphoma is a rare lymphoproliferative disorder that can mimic cutaneous lymphoma. The condition can present acutely with concerns of perianal sepsis. The purpose of this case review is to review the current literature on perianal pseudolymphoma and emphasise to the surgical community its presentation, suggested aetiology and management. Read More

    Possible role of Helicobacter pylori in diseases of dermatological interest.
    J Biol Regul Homeost Agents 2017 APR-JUN;31(2 Suppl. 2):57-77
    Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy.
    Helicobacter pylori is a gram-negative, flagellate, microaerophilic bacterium identified for the first time about 30 years ago, as a pathogenic factor of gastritis and peptic ulcer. Soon after, it was linked to several gastrointestinal and extra-gastrointestinal diseases (hematological, cardiovascular, neurological, pulmonary and ocular diseases, obesity, diabetes mellitus, growth retardation and extragastric MALT lymphoma). Association and possible cause-effect correlation with H. Read More

    Acral angiokeratoma-like pseudolymphoma in a middle-aged woman.
    J Cutan Pathol 2017 Oct 24;44(10):878-881. Epub 2017 Jul 24.
    Dermatology Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center and Weill Cornell Medical College, New York, New York.
    Acral angiokeratoma-like pseudolymphoma is a rare type of pseudolymphoma presenting as dark-red papules on the hand or foot. We describe a 59-year-old woman who presented with an unusual unilateral, clustered aggregate of scaly violaceous papules on the toe with an indolent course. Skin biopsy showed a prominent vascular proliferation associated with a dermal infiltrate of monoclonally rearranged T-follicular helper phenotype T-cells, in keeping with CD4+ small/medium T-cell lymphoproliferative disorder (SMPTC-LPD). Read More

    Atypical presentations of cutaneous leishmaniasis: A systematic review.
    Acta Trop 2017 Aug 17;172:240-254. Epub 2017 May 17.
    Laboratory of Microbiology and Parasitology, Faculty of Medicine, Federal University of Cariri, UFCA, Barbalha, Ceará, Brazil. Electronic address:
    Cutaneous Leishmaniasis (CL) is endemic in 88 countries, showing relevant prevalences. The aim of this study was to perform a systematic review on atypical lesions of CL around the world, addressing clinico-epidemiological, immunological and therapeutic aspects. A search of the literature was conducted via electronic databases Scopus and PubMed for articles published between 2010 and 2015. Read More

    Cutaneous Pseudolymphoma.
    Surg Pathol Clin 2017 Jun 22;10(2):455-476. Epub 2017 Mar 22.
    Kempf & Pfaltz, Histologische Diagnostik, Seminarstrasse 1, 8057 Zürich, Zurich, Switzerland; Department of Dermatology, University Hospital Zurich, Gloriastrassse 31, 8091 Zürich, Switzerland.
    The term, cutaneous pseudolymphoma (PSL), refers to a group of lymphocyte-rich infiltrates, which either clinically and/or histologically simulate cutaneous lymphomas. Clinicopathologic correlation is essential to achieve the final diagnosis in cutaneous PSL and to differentiate it from cutaneous lymphomas. A wide range of causative agents (eg, Borrelia, injections, tattoo, and arthropod bite) has been described. Read More

    Chronic amastigote-negative cutaneous leishmaniasis: A clinical, histopathologic and molecular study of 27 cases with emphasis on atypical and pseudolymphomatous presentations.
    J Cutan Pathol 2017 Jun 10;44(6):530-537. Epub 2017 Apr 10.
    Microbiology and Virology Unit, Azienda Ospedaliero Universitaria Città della Salute e della Scienza, Turin, Italy.
    Background: Chronic amastigote-negative cutaneous leishmaniasis (CL) is a diagnostic challenge, as the parasite load may be low, or absent in biopsy tissue sections.

    Methods: A series of consecutive biopsy specimens, taken from 130 patients with a diagnosis of granulomatous dermatitis of unknown etiology, were reviewed. Polymerase chain reaction (PCR) was carried out for Leishmania-specific DNA. Read More

    Injection-Site Cutaneous Pseudolymphoma Induced by a GM-CSF-Producing Tumor Cell Vaccine.
    JAMA Dermatol 2017 Apr;153(4):332-334
    Division of Dermatology, Department of Medicine, Washington University, St Louis, Missouri2Department of Pathology and Immunology, Washington University, St Louis, Missouri3Dermatopathololgy Center, Washington University, St Louis, Missouri.

    Lymphocytoma cutis: diagnostic enigma for the maxillofacial surgeon.
    J Korean Assoc Oral Maxillofac Surg 2016 Dec 27;42(6):379-382. Epub 2016 Dec 27.
    Department of Oral Pathology and Microbiology, KLE Viswanath Katti Institute of Dental Sciences, KLE University, Belagavi, India.
    Cutaneous lymphoid hyperplasia (CLH) is a cutaneous pseudolymphoma with a worldwide distribution, equally affecting all races and ethnic groups. Due to its vast array of characteristics, it is most often missed in the differential diagnosis of firm to soft lumps on the head and neck. A systematic approach to the workup and diagnosis along with treatment of such lesions is discussed in this article. Read More

    [Differential diagnosis of basal cell carcinoma of the face: Dermatologist advice may avoid surgery].
    Rev Stomatol Chir Maxillofac Chir Orale 2016 Nov 14;117(5):335-339. Epub 2016 Jul 14.
    Aix Marseille université, 13916 Marseille, France; Service de dermatologie, hôpital Nord, AP-HM, 13915 Marseille cedex 20, France.
    Introduction: Basal cell carcinoma (BCC) is the most common skin cancer in France. It is commonly diagnosed in front of a papule or nodule of the face. The surgeon should be able to question the diagnosis of BCC when nodular lesions are untypical, keeping in mind that some differential diagnoses require only medical treatment. Read More

    Cutaneous metastasis of inflammatory breast carcinoma mimicking an erythema annulare centrifugum: a sign of locally recurrent cancer.
    Clin Exp Dermatol 2016 Dec 20;41(8):906-910. Epub 2016 Oct 20.
    Department of Oncology, Hospital Casa de Salud, Valencia, Spain.
    Erythema annulare centrifugum (EAC) is a clinical reaction pattern that includes lupus erythematosus, spongiotic dermatitis (particularly pityriasis rosea), pseudolymphoma and cutaneous B-cell lymphoma. However, it can be the result of cutaneous metastasis by an internal carcinoma. We present the case of a 38-year-old woman with bilateral inflammatory breast cancer following multimodal therapy. Read More

    Tinea on a Tattoo.
    Acta Dermatovenerol Croat 2016 Aug;24(3):223-4
    Marius Irimie, MD, 40, Zizinului Street, Bl. 31, Sc. C, Ap. 2, 500414, Brasov, Romania;
    In the last twenty years, the prevalence of individuals with tattoos in the general population has increased in Europe (1) as well as in Australia (2) and the United States of America (3). A series of complications such as acute inflammatory reactions, allergic contact dermatitis (4,5), photoinduced, lichenoid, and granulomatous reactions (6, 7), pseudolymphoma (8), pseudoepitheliomatous hyperplasia (9), skin infections (6), and skin cancers (10) may occur on tattoos. Infectious complications on tattoos include bacterial infections (pyoderma, leprosy, syphilis, cutaneous tuberculosis, mycobacteriosis) (11-14), viral infections (molluscum contagiosum, warts, herpes simplex, hepatitis B and C) (15-17), and fungal infections (sporotrichosis, dermatophytosis) (18,19). Read More

    Papular angiolymphoid hyperplasia and lymphoplasmacytic plaque: a clinical and histological spectrum.
    Dermatol Online J 2016 Apr 18;22(4). Epub 2016 Apr 18.
    Singapore General Hospital.
    Acral pseudolymphomatous angiokeratoma of children (APACHE) is a rare form of cutaneous pseudolymphoma characterized byangiomatous papules with a predilection for the acral regions of children. Classically, a dense dermal lymphocytic infiltrate composed of both T and B cells is seen in histological specimens, together with prominent vessels lined by plump endothelial cells. Increasing evidence suggests that this condition is neither necessarily acral, pseudolymphomatous, nor angiokeratomatous. Read More

    Pseudolymphoma versus lymphoma: An important diagnostic decision.
    J Oral Maxillofac Pathol 2016 May-Aug;20(2):328
    Department of Conservative Dentistry and Endodontics, Farooqia Dental College, Mysuru, Karnataka, India.
    Small innocuous growths on the face usually do not pose difficulty in diagnosis on histopathology. However, some benign inflammatory lesions might mimic malignancy and hence need further investigations for final diagnosis. The distinction between a benign/inflammatory/malignant lesion needs no emphasis as the treatment plan, prognosis and the patient's well-being depends on it. Read More

    Approach to Cutaneous Lymphoid Infiltrates: When to Consider Lymphoma?
    Indian J Dermatol 2016 Jul-Aug;61(4):351-74
    Department of Dermatology and Pathology, University of California, San Francisco, United States of America.
    Cutaneous lymphoid infiltrates (CLIs) are common in routine dermatopathology. However, differentiating a reactive CLI from a malignant lymphocytic infiltrate is often a significant challenge since many inflammatory dermatoses can clinically and/or histopathologically mimic cutaneous lymphomas, coined pseudolymphomas. We conducted a literature review from 1966 to July 1, 2015, at PubMed. Read More

    Cutaneous Pseudolymphomas.
    Actas Dermosifiliogr 2016 Oct 8;107(8):640-51. Epub 2016 Jun 8.
    Servicio de Dermatología, Hospital General Universitario de Alicante, Alicante, España.
    The term cutaneous pseudolymphoma refers to benign reactive lymphoid proliferations in the skin that simulate cutaneous lymphomas. It is a purely descriptive term that encompasses various reactive conditions with a varied etiology, pathogenesis, clinical presentation, histology, and behavior. We present a review of the different types of cutaneous pseudolymphoma. Read More

    Radiotherapy in aggressive cutaneous pseudolymphoma: a case report and review of literature.
    Radiat Oncol J 2016 Mar 30;34(1):76-80. Epub 2016 Mar 30.
    Department of Radiation Oncology, Nizam's Institute of Medical Sciences, Hyderabad, India.
    Pseudolymphoma is a nonspecific disease characterized by lesions with lymphomatous-appearing but benign accumulation of inflammatory cells. They generally present as small ulcero-nodular lesions confined to skin which often respond to local therapies. We describe an unusual presentation of an extensive and locally aggressive cutaneous pseudolymphoma in a 21-year-old male patient who presented with extensive cutaneous eruptions gradually progressing over 6 years to involve the entire circumference of his left arm. Read More

    Differential NFATc1 Expression in Primary Cutaneous CD4+ Small/Medium-Sized Pleomorphic T-Cell Lymphoma and Other Forms of Cutaneous T-Cell Lymphoma and Pseudolymphoma.
    Am J Dermatopathol 2017 Feb;39(2):95-103
    Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY.
    Background: Primary cutaneous CD4 small/medium-sized pleomorphic T-cell lymphoma (PCSTCL) has recently emerged as a distinct clinicopathological entity. Because of a considerable degree of overlap with pseudolymphoma, the diagnosis is often challenging. Preliminary studies suggest that nuclear upregulation of calcineurin/nuclear factor of activated T cells (NFAT) may play a role in lymphomagenesis. Read More

    Lamotrigine-induced Hypersensitivity Syndrome with Histologic Features of CD30+ Lymphoma.
    Indian J Dermatol 2016 Mar-Apr;61(2):235
    Department of Oncology, Bellevue Medical Center, Beirut, Lebanon.
    Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome or drug-induced hypersensitivity syndrome (DIHS) is a severe adverse drug reaction. It can present with clinical, paraclinical, and histological findings mimicking skin and/or systemic lymphomas. We report the first case of a lamotrigine-induced DRESS with histologic features of a cutaneous CD30+ lymphoma. Read More

    Late-onset Anticonvulsant Hypersensitivity Syndrome Mimicking Lymphoma.
    Intern Med 2015 15;54(24):3201-4. Epub 2015 Dec 15.
    Department of Hematology, Kocaeli University Medical Faculty, Turkey.
    Anticonvulsant hypersensitivity syndrome is a fatal, idiosyncratic drug reaction that is caused by aromatic antiepileptic drugs. This cutaneous drug reaction is also called pseudolymphoma because of its clinical and histological similarities with malignant lymphoma. The primary clinical findings are fever, skin rashes, enlarged lymph nodes, single or multiple internal organ involvement and hematological abnormalities. Read More

    CD30-positive Cutaneous Pseudolymphoma Caused by Tocilizumab in a Patient with Rheumatoid Arthritis: Case Report and Literature Review.
    Acta Derm Venereol 2016 May;96(4):570-1
    Department of Dermatology, University of Occupational and Environmental Health. 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu 807-8555, Japan.

    Phenytoin Induced Cutaneous B Cell Pseudolymphoma.
    Indian J Dermatol 2015 Sep-Oct;60(5):522
    Department of Dermatology and Venereology, Govt Medical College, Kozhikode, Kerala, India.
    Cutaneous pseudolymphomas are benign lymphoproliferative processes mimicking lymphomas clinically and histologically. One of the precipitating factors for pseudolymphoma is drugs like anticonvulsants, antidepressants and angiotensin-converting enzyme inhibitors. According to existing literature phenytoin-induced cutaneous pseudolymphomas are usually T-cell predominant. Read More

    Linear acral pseudolymphomatous angiokeratoma of children with associated nail dystrophy.
    Dermatol Online J 2015 Jul 15;21(7). Epub 2015 Jul 15.
    Baylor Scott & White Health, Texas A&M Health Science Center.
    Acral pseudolymphomatous angiokeratoma of children (APACHE) is a rare entity that typically occurs on the extremities of young females. Although linear arrangement of cutaneous lesions has been rarely reported, accompanying nail dystrophy has not been linked with this condition to our knowledge. We describe a case of linearly-oriented infiltrative papules and nodules on the index finger of a young female with associated onychodystrophy. Read More

    Asymptomatic papules over central and pericentral areas of the face.
    Indian Dermatol Online J 2015 May-Jun;6(3):198-200
    Department of Dermatology, Venereology and Leprosy, IPGMER and SSKM Hospital, Kolkata, West Bengal, India.
    We report the case of a 24-year-old college girl, presenting with numerous acneiform papular eruptions over the central part of the face. Read More

    Persisting allergic patch test reaction to minoxidil manifested as cutaneous lymphoid hyperplasia.
    Contact Dermatitis 2015 Jun 20;72(6):413-6. Epub 2015 Mar 20.
    Department of Dermatology, Faculty of Medicine, University Hospital Complex, 15706, Santiago de Compostela, Spain.

    Cutaneous borreliosis associated with T cell-predominant infiltrates: a diagnostic challenge.
    J Am Acad Dermatol 2015 Apr 21;72(4):683-9. Epub 2015 Jan 21.
    Dermatopathologie Friedrichshafen, Friedrichshafen, Germany.
    Background: With the exception of erythema migrans, Borrelia infection of the skin manifests much more commonly with B cell-rich infiltrates. T cell-rich lesions have rarely been described.

    Objective: We report a series of 6 patients with cutaneous borreliosis presenting with T cell-predominant skin infiltrates. Read More

    The importance of histopathology findings in lymphomatoid papulosis.
    Rom J Morphol Embryol 2014 ;55(4):1527-30
    Discipline of Dermatology, Faculty of Medicine, "Grigore T. Popa" University of Medicine and Pharmacy, Clinic of Dermato-venereology, "St. Spiridon" Emergency Hospital, Iassy, Romania;
    Lymphomatoid papulosis, part of the controversial group of cutaneous lymphoproliferative pseudolymphoma disorders, raises important clinical and histopathological problems. It is a chronic, recurrent, clinically characterized by popular necrotic lesions and papulo-pustular nodules, sometimes self-limiting and characterized by histopathological changes suggestive of cutaneous lymphoma (CD30-positive). Since its introduction, in 1968, the term "lymphomatoid papulosis" was subject to dispute in terms of classification in malignancies, premalignant or benign skin disease. Read More

    A variant of palpable migratory arciform erythema.
    J Drugs Dermatol 2014 Oct;13(10):1288-9
    Palpable migratory arciform erythema is a T-cell pseudolymphoma with no well-established treatment. The disease is rarely reported in the literature, perhaps because it is difficult to diagnose. We present a case of a variant of PMAE in a 30-year-old healthy man with no history of medication use and erythematous to violaceous annular and arciform plaques on his face, scalp and trunk. Read More

    [Cutaneous lymphomas: new entities and rare variants].
    Pathologe 2015 Feb;36(1):62-9
    Kempf und Pfaltz, Histologische Diagnostik, Seminarstr. 1, 8042, Zürich, Schweiz,
    Primary cutaneous lymphomas are the second most common group of extranodal non-Hodgkin lymphomas. Recently several new variants and entities have been described but have not yet become part of the World Health Organization (WHO) classification. These forms include the granulomatous form of mycosis fungoides, which is associated with a poorer prognosis, as well as indolent CD8+ lymphoproliferations on the head and at acral localizations. Read More

    Borrelial lymphocytoma cutis: a diagnostic dilemma.
    Indian J Dermatol 2014 Nov;59(6):595-7
    Consultant Pathologist, OncQuest Laboratories, 3 Factory Road, New Delhi, India.
    Lymphocytoma cutis (LC) is one of the most common types of cutaneous B cell pseudolymphoma. Borrelial LC occurs most commonly in areas endemic for Ixodes ricinus tick in Europe, and it is rare in North America. The disease is rarely seen in India and may cause diagnostic difficulties for dermatologist residing in parts of the world that are not endemic for Lyme disease. Read More

    Stenotrophomonas maltophilia with histopathological features mimicking cutaneous gamma/delta T-cell lymphoma.
    Int J Infect Dis 2015 Jan 13;30:7-9. Epub 2014 Nov 13.
    Department of Dermatology, The University of Texas Medical School at Houston and MD Anderson Cancer Center, 1400 Pressler Street Unit 1452, Houston, TX 77030, USA.
    We report a case of cutaneous Stenotrophomonas maltophilia infection which presented with clinical and histopathological findings that mimicked a gamma/delta (γδ) T-cell lymphoma. In this case, tissue culture of the biopsy specimen was key to determining the diagnosis and allowing appropriate treatment with oral trimethoprim-sulfamethoxazole and topical silvadene. A prompt complete resolution of lesions was observed following antibiotic treatment, with no recurrence of disease over the last 5 years, supporting an infectious rather than malignant etiology. Read More

    T-cell-predominant lymphoid hyperplasia in a tattoo.
    An Bras Dermatol 2014 Nov-Dec;89(6):1019-21
    Cutaneous lymphoid hyperplasia (CLH) can be idiopathic or secondary to external stimuli, and is considered rare in tattoos. The infiltrate can be predominantly of B or T-cells, the latter being seldom reported in tattoos. We present a case of a predominantly T CLH, secondary to the black pigment of tattooing in a 35-year-old patient, with a dense infiltrate of small, medium and scarce large T-cells. Read More

    PD-1, S-100 and CD1a expression in pseudolymphomatous folliculitis, primary cutaneous marginal zone B-cell lymphoma (MALT lymphoma) and cutaneous lymphoid hyperplasia.
    J Cutan Pathol 2015 Jan 11;42(1):6-15. Epub 2014 Dec 11.
    Dermatopathology Unit, Massachusetts General Hospital, Boston, MA, USA.
    Background: Pseudolymphomatous folliculitis is a lymphoid proliferation that clinically and histopathologically mimics primary cutaneous extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma). In this study, we assessed the diagnostic value of three immunohistochemical markers, programmed death-1 (PD-1), CD1a and S100.

    Methods: We evaluated 25 cases of cutaneous lymphoid proliferations with established diagnoses, including 9 patients with pseudolymphomatous folliculitis, 11 with MALT lymphoma, and 5 with cutaneous lymphoid hyperplasia (CLH). Read More

    T cell lymphomatoid contact dermatitis: a challenging case and review of the literature.
    Contact Dermatitis 2015 Feb 24;72(2):65-74. Epub 2014 Oct 24.
    Section of Dermatology, Department of Surgery, Dartmouth-Hitchcock Medical Center, One Medical Center Drive, Lebanon, NH 03766, USA.
    Lymphomatoid contact dermatitis is a pseudolymphoma with clinical and histological features of allergic contact dermatitis and cutaneous T cell lymphoma. Incorrect diagnosis may lead to unnecessary testing, unnecessary treatment, or patient harm. The objective of this study is to present a case to demonstrate the diagnostic challenge and overlap between allergic contact dermatitis and cutaneous T cell lymphoma in a patient with lymphomatoid contact dermatitis caused by methylchoroisothiazolinone/methylisothiazolinone and paraben mix, and to review the existing literature in order to summarize the demographics, clinical features, allergens and treatments reported for lymphomatoid contact dermatitis. Read More

    Selected inflammatory imitators of mycosis fungoides: histologic features and utility of ancillary studies.
    Arch Pathol Lab Med 2014 Oct;138(10):1319-27
    From the Departments of Pathology (Drs Arps, Chen, Fullen, and Hristov) and Dermatology (Drs Fullen and Hristov), University of Michigan, Ann Arbor.
    Mycosis fungoides is the most common primary cutaneous lymphoma; however, it remains a significant diagnostic challenge, in part because of the overlap with several inflammatory dermatoses. Despite advances in immunohistochemistry and molecular diagnostics, false-positive, false-negative, and indeterminate diagnoses are not uncommon. In most cases, the overall balance of morphologic, immunophenotypic, and genetic features must be considered carefully because there are few sensitive and specific clues to the diagnosis. Read More

    Controversies and considerations in the diagnosis of primary cutaneous CD4⁺ small/medium T-cell lymphoma.
    Arch Pathol Lab Med 2014 Oct;138(10):1307-18
    From the Departments of Pathology (Drs Lan, Brown, and Hristov) and Dermatology (Drs Lan and Hristov), University of Michigan Health System, Ann Arbor.
    Context: Primary cutaneous CD4⁺ small/medium T-cell lymphoma is a provisional and controversial entity with a broad differential diagnosis. Despite being an uncommon lymphoma, it is a frequent diagnostic consideration in cutaneous biopsies with a dense lymphoid infiltrate because it shows overlapping features with reactive lymphoid hyperplasia (pseudolymphoma) and a variety of other primary cutaneous and systemic lymphomas. However, proper classification of this process is important for determining patient prognosis and treatment options. Read More

    Drug-induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic symptoms with histologic features mimicking cutaneous pseudolymphoma.
    J Dermatol 2014 Sep 25;41(9):856-7. Epub 2014 Aug 25.
    Department of Dermatology, Showa University School of Medicine, Tokyo, Japan; Division of Dermatology, Showa University Fujigaoka Hospital, Yokohama, Japan.

    T-cell rich angiomatoid polypoid pseudolymphoma: a novel cutaneous pseudolymphoma.
    Indian J Dermatol 2014 Jul;59(4):361-3
    Department of Dermatology, PSG Institute of Medical Sciences and Research, Coimbatore, Tamil Nadu, India.
    Cutaneous pseudolymphomas refer to a group of benign reactive T or B cell lymphoproliferative processes that simulate cutaneous lymphomas. T cell rich angiomatoid polypoid pseudo lymphoma (TRAPP) of the skin is a unique form of T cell rich cutaneous pseudolymphoma. A 13-year-girl presented with an asymptomatic skin colored papule on the right elbow, the biopsy of which revealed features consistent with TRAPP. Read More

    IgG4-related skin disease.
    Br J Dermatol 2014 Nov 20;171(5):959-67. Epub 2014 Oct 20.
    Department of Dermatology, Hamamatsu University School of Medicine, 1-20-1 Handayama, Higashi-ku, Hamamatsu, 431-3192, Japan.
    IgG4-related disease (IgG4-RD) is a recently established clinical entity characterized by high levels of circulating IgG4, and tissue infiltration of IgG4(+) plasma cells. IgG4-RD exhibits a distinctive fibroinflammatory change involving multiple organs, such as the pancreas and salivary and lacrimal glands. The skin lesions of IgG4-RD have been poorly characterized and may stem not only from direct infiltration of plasma cells but also from IgG4-mediated inflammation. Read More

    Severe drug-induced dermatoses.
    Semin Cutan Med Surg 2014 Mar;33(1):49-58
    Department of Dermatology, University of California San Francisco, CA USA. Email:
    A variety of common dermatoses are known to have drug-induced variants. This article discusses the clinical presentation, time frames, reported culprit medications, pathophysiology and management of drug-induced lupus, cutaneous vasculitis, pemphigus, pemphigoid, linear IgA bullous dermatosis, Sweet's syndrome, erythema nodosum, pyoderma gangrenosum, pseudolymphoma, lichen planus, and psoriasis. Read More

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