105 results match your criteria Pruritic Urticarial Papules and Plaques of Pregnancy
J Clin Diagn Res 2017 May 1;11(5):WC01-WC05. Epub 2017 May 1.
Associate Professor, Department of Dermatology, Venereology and Leprosy, Villupuram Medical College, Villupuram, Tamil Nadu, India.
Introduction: Pregnancy produces many cutaneous changes, some of which are specifically related to pregnancy (dermatoses of pregnancy), some are modifiable by pregnancy and others that are common are named physiologic. These physiologic skin changes, usually do not impair the health of the mother or the fetus but some of them can be cosmetically significant and of importance to the dermatologist.
Aim: The present study was undertaken to find out the prevalence of the physiological and pathological skin changes in pregnancy, and to correlate the prevalence of the major cutaneous changes and diseases in relation to different trimesters of pregnancy and with gravidity. Read More
Case Rep Dermatol 2017 Jan-Apr;9(1):151-156. Epub 2017 Apr 27.
Department of Dermatology, Cheil General Hospital and Women's Healthcare Center, Dankook University College of Medicine, Cheonan, Republic of Korea.
Pruritic urticarial papules and plaques of pregnancy (PUPPP) is one of the most common diseases associated with pregnancy. In most cases, the skin lesions develop in the third trimester of primigravidas. There are no systemic alterations seen in PUPPP; however, most patients report severe pruritus. Read More
An Bras Dermatol 2016 Sep-Oct;91(5 suppl 1):66-68
Universidade Federal Fluminense (UFF) - Niterói (RJ), Brazil.
Pruritic folliculitis of pregnancy is a rare disease of unknown etiology. It occcurs primarily during pregnancy, usually with spontaneous resolution postpartum. It is characterized by a benign dermatosis, with papular and pustular follicular lesions that first appear on the torso and occasionally spread throughout the body. Read More
J Am Acad Dermatol 2017 Mar;76(3):560-562
Department of Dermatology, INSERM U1234, Rouen University Hospital, University of Rouen, France. Electronic address:
Hautarzt 2017 Feb;68(2):87-94
Hautklinik, Universitätsklinikum Erlangen, Ulmenweg 18, 91054, Erlangen, Deutschland.
The specific dermatoses of pregnancy represent a heterogeneous group of inflammatory skin diseases related to pregnancy and/or the postpartum period. A clinically relevant classification has been well established over the past 10 years and includes pemphigoid gestationis, polymorphic eruption of pregnancy, intrahepatic cholestasis of pregnancy, and atopic eruption of pregnancy. The hallmark of all four entities is severe pruritus that is accompanied by characteristic skin changes. Read More
J Obstet Gynaecol 2017 Feb 14;37(2):137-140. Epub 2016 Dec 14.
a Department of Obstetrics and Gynaecology , Centro Hospitalar Tâmega e Sousa, Hospital Padre Américo , Penafiel , Portugal.
Polymorphic Eruption of Pregnancy (PEP) is one of the most common dermatosis related to pregnancy. PEP usually consists of pruritic papules and plaques appearing in the third trimester of pregnancy. It is more common in primigravidae and twin pregnancies. Read More
J Epidemiol Glob Health 2017 03 19;7(1):63-70. Epub 2016 Nov 19.
Department of Dermatology, Government Medical College, Alappuzha, Kerala, India.
Background/objective: Pregnant women experience a myriad of physiological and metabolic changes that affect different organ systems in the body. Cutaneous and appendageal alterations that manifest during pregnancy are largely modulated by hormonal, immunologic, and metabolic factors. Detailed reports encompassing physiological changes and specific dermatoses of pregnancy and effects of various dermatoses on pregnant women are scanty in literature. Read More
Curr Probl Dermatol 2016 23;50:164-72. Epub 2016 Aug 23.
Department of Dermatology, University Hospital of Antwerp, University of Antwerp, Edegem, Belgium.
Pruritus is common in pregnancy. It deserves an elaborated work-up of the patient. It is frequently a symptom of a dermatosis that coincides by chance with pregnancy or a preexisting dermatosis that can flare during pregnancy. Read More
Clin Dermatol 2016 May-Jun;34(3):383-91. Epub 2016 Feb 9.
Department of Dermatology, University of Illinois at Chicago College of Medicine, Chicago, Illinois.
Polymorphic eruption of pregnancy (PEP), a specific dermatosis of pregnancy also known as pruritic urticarial papules and plaques of pregnancy (PUPPP), is a benign, self-limited skin disorder. Key features include an increased prevalence in primigravidas, onset in the third trimester, remission near the time of delivery, and association with multiple gestation pregnancy. The clinical features are crucial to diagnosis. Read More
J Dermatol Case Rep 2016 Mar 31;10(1):19-20. Epub 2016 Mar 31.
Department of Experimental and Clinical Medicine, Institute of Dermatology, University of Udine, Italy.
Pruritic folliculitis of pregnancy is a noninfective dermatosis of the gestation period characterized by multiple pruritic follicular papules and/or pustules which is not uncommonly mistaken for other similar skin disorders that may occur during pregnancy. In the present article we describe the usefulness of dermoscopy as a supportive diagnostic tool in a case of pruritic folliculitis of pregnancy. The main (always present) dermoscopic clue consisted of a vellus hair in the centre of each papule/pustule. Read More
J Reprod Med 2015 May-Jun;60(5-6):265-8
Background: Anaplastic large cell lymphoma is rarely diagnosed during pregnancy, and patients may be erroneously diagnosed with a dermatosis.
Case: A 34-year-old female was diagnosed with pruritic urticarial papules and plaques of pregnancy in the third trimester. She underwent elective repeat cesarean section with a postoperative course complicated by skin and gingival ulcers and persistent fever. Read More
Cutis 2015 Jun;95(6):344-7
Mid-Michigan Dermatology, PLLC, Office Park West, 416 S Creyts Rd, Lansing, MI 48917, USA.
Pruritic urticarial papules and plaques of pregnancy (PUPPP)(also known as polymorphic eruption of pregnancy in Europe) is an intensely pruritic eruption that affects women during the third trimester of pregnancy. Treatment usually is aimed at symptom relief until delivery, as the eruption usually resolves rapidly in the postpartum period. We report the case of a 30-year-old woman who presented 2 weeks postpartum with an intensely pruritic generalized eruption. Read More
Clin Obstet Gynecol 2015 Mar;58(1):104-11
Division of Dermatology, Department of Medicine-Clinical, Ohio State University College of Medicine, Gahanna, Ohio.
The dermatoses of pregnancy represent a distinct heterogenous group of cutaneous disorders that can impact the health of the pregnant woman and potentially the fetus. The current classification of pregnancy-specific cutaneous disorders is reviewed, along with important clinical features. Advances in management of these disorders, along with fetal implications, are discussed. Read More
Am J Dermatopathol 2014 Oct;36(10):812-21
*Department of Dermatology, Medical University of Graz, Graz, Austria; †Department of Dermatology, Universitad Técnica Particular de Loja, Loja, Ecuador; and ‡Department of Dermatology, University of L'Aquila, L'Aquila, Italy.
The specific dermatoses of pregnancy represent a recently reclassified heterogeneous group of pruritic inflammatory skin diseases unique to pregnancy that include pemphigoid gestationis, polymorphic eruption of pregnancy (PEP), intrahepatic cholestasis of pregnancy, and atopic eruption of pregnancy (AEP). Among them, PEP and AEP are the most frequent ones. We performed a histopathological study of a series of PEP and AEP patients (n = 41). Read More
Arerugi 2014 Feb;63(2):147-54
Department of Dermatology, Saitama Medical University, Saitama Medical Center.
J Eur Acad Dermatol Venereol 2015 Apr 5;29(4):797-800. Epub 2014 Mar 5.
Department of Dermatology, Gangnam Severance Hospital, Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul, Korea.
Background: Pruritic urticarial papules and plaques of pregnancy (PUPPP), also known as polymorphic eruption of pregnancy, is a common and benign but exceedingly uncomfortable dermatosis of pregnancy. Investigation of new treatment options has been limited by patient concerns about the negative fetal effects of medication.
Objective: To assess the efficacy of intramuscular injection of autologous whole blood (AWB) for treatment of PUPPP. Read More
Ann Dermatol 2013 Nov 30;25(4):506-8. Epub 2013 Nov 30.
Department of Dermatology, Institute of Hair and Cosmetic Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea.
Can Fam Physician 2013 Dec;59(12):1290-4
Question: Some of my pregnant patients complain about pruritus. Are there conditions in pregnancy that present with pruritus that might put the mother or fetus at risk?
Answer: Although most cases of pruritus can be attributed to itchy dry skin, there are conditions unique to pregnancy that involve pruritus as a leading symptom. These include pemphigoid gestationis, pruritic urticarial papules and plaques of pregnancy, intrahepatic cholestasis of pregnancy, and atopic eruption of pregnancy. Read More
Am J Dermatopathol 2013 Dec;35(8):787-91
*Dermpath Diagnostics New York, Port Chester, NY; †Department of Pathology, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY; and ‡Department of Dermatology, New York Medical College, Valhalla, NY.
Polymorphic eruption of pregnancy (PEP), formerly known as pruritic urticarial papules and plaques of pregnancy, is a dermatosis of pregnancy that must be distinguished from pemphigoid gestationis (PG). Although this differential diagnosis may be possible on routine histology, an additional biopsy for direct immunofluorescence (DIF) is often needed. Recent studies have demonstrated the utility of anti-C4d or anti-C3d antibodies in the diagnosis of bullous pemphigoid (BP) in formalin-fixed paraffin-embedded tissue (FFPE). Read More
Dermatol Ther 2013 Jul-Aug;26(4):274-84
The Ronald O. Perelman Department of Dermatology, New York University, New York, New York 10016, USA.
The specific dermatoses of pregnancy represent a diverse group of intensely pruritic dermatoses, occurring only in the puerperal state. The relative rarity of these conditions, the often variable clinical appearance, and the lack of definitive diagnostic tests have led to confusion regarding the appropriate diagnosis and management of the specific dermatoses of pregnancy. Herein we review the clinical characteristics, diagnosis and treatment of five dermatoses occurring during pregnancy: pruritic urticarial papules and plaques of pregnancy, atopic eruption of pregnancy, pemphigoid gestationis, intrahepatic cholestasis of pregnancy, and pustular psoriasis of pregnancy. Read More
Case Rep Dermatol 2013 May 3;5(2):138-43. Epub 2013 May 3.
Department of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Background: Skin lesions in pregnant women could be caused by physiologic or pathologic changes. Polymorphic eruption of pregnancy (PEP), which manifests as various types of skin lesions, is the most common pregnancy dermatosis. Thus, PEP could mimic other skin diseases related to unfavorable maternal and fetal outcomes. Read More
Int J Dermatol 2012 Sep;51(9):1047-53
Department of Obstetrics, American University of Beirut-Medical Center, Beirut, Lebanon.
Background: Pruritic urticarial papules and plaques of pregnancy (PUPPP) is a benign pruritic inflammatory skin disorder that usually affects primigravidae in their third trimester of pregnancy. Studies on this condition from our area are lacking.
Objective And Methods: To describe the epidemiological, clinical, and histopathological findings of all patients diagnosed with PUPPP at the American University of Beirut Medical Center (AUB-MC) between 1998 and 2009 and compare our findings with those published in the literature. Read More
J Dermatol Case Rep 2011 Dec;5(4):69-73
Dept. of Dermatology & Venereology, Lady Hardinge Medical College, New Delhi, 11000, India.
Background: The specific dermatoses of pregnancy represent a heterogenous group of ill-defined pruritic skin diseases, unique to pregnancy and post partum period.
Objective: The aim of our study was epidemiological and clinical evaluation of various specific dermatoses of pregnancy.
Methods: All patients visiting our antenatal clinic were screened for various pruritic skin conditions and those with specific pregnancy dermatoses were identified and evaluated. Read More
J Obstet Gynaecol 2012 Apr;32(3):301-2
Department of Biomedical Sciences, University of Ferrara, Ferrara, Italy.
Dermatol Reports 2012 Jan 6;4(1):e7. Epub 2012 Jun 6.
Department of Dermato-venerology, Stavanger University Hospital, Stavanger, Norway.
Polymorphic eruption of pregnancy (PEP), also known as pruritic urticarial papules and plaques of pregnancy, is a common benign dermatosis of pregnancy mainly affecting primigravidae and multiple pregnancies. We report here two cases of PEP with typical clinical and histological features presenting in the postpartum period. Read More
Eur J Dermatol 2012 Jan-Feb;22(1):136-7
BMJ 2011 Sep 19;343:d5325. Epub 2011 Sep 19.
St John's Institute of Dermatology, Guy's and St Thomas' NHS Foundation Trust, London SE1 7EH, UK.
Ann Dermatol 2011 Aug 6;23(3):265-75. Epub 2011 Aug 6.
Department of Dermatology, Medical University of Graz, Graz, Austria.
The specific dermatoses of pregnancy represent a heterogeneous group of pruritic skin diseases that have been recently reclassified and include pemphigoid (herpes) gestationis, polymorphic eruption of pregnancy (syn. pruritic urticarial papules and plaques of pregnancy), intrahepatic cholestasis of pregnancy, and atopic eruption of pregnancy. They are associated with severe pruritus that should never be neglected in pregnancy but always lead to an exact work-up of the patient. Read More
Clin Dermatol 2011 Sep-Oct;29(5):504-8
Dermatology Unit, Kaplan Medical Center, 76100 Rechovot, Israel (affiliated to the Hebrew University-Hadassah Medical School, Jerusalem, Israel).
What is probably the first description of targetoid or iris lesions, as they appear in erythema multiforme (EM), can be found in Thomas Bateman's 1836 textbook "Practical Synopsis of Cutaneous Diseases According to the Arrangement of Dr. Willan." EM was initially described by Bateman and later by von Hebra as an acute self-limiting skin disease, symmetrically distributed on the extremities with typical concentric "targetoid" or "iris" lesions, and often recurrent. Read More
Practitioner 2011 Feb;255(1737):29-30
Leicester Royal Infirmary.
J Obstet Gynaecol Res 2011 Aug 19;37(8):1158-61. Epub 2011 Apr 19.
Department of Dermatology, Muş State Hospital, Muş, Turkey.
Polymorphic eruption of pregnancy is the most common specific dermatosis of pregnancy. It usually develops in the third trimester and rapidly resolves in the first weeks postpartum. Intensely pruritic urticarial papules and plaques initially occur on the abdomen and/or proximal thighs, particularly within or adjacent to striae distensae with periumbilical sparing, and usually tend to spread to affect the peripheral limbs, buttocks, chest and back. Read More
Dermatol Online J 2010 Nov 15;16(11):10. Epub 2010 Nov 15.
Department of Dermatology, New York University, New York, NY, USA.
Pemphigoid gestationis is a rare autoimmune blistering disease of pregnancy. It is characterized by pruritic, urticarial plaques with the development of tense vesicles and bullae within the lesions. Pemphigoid gestationis has been associated with premature delivery, small-for-gestational-age infants. Read More
Hautarzt 2010 Dec;61(12):1027-33
Klinik für Dermatologie, Venerologie und Allergologie, Universität Leipzig, Philipp-Rosenthal-Str. 23, 04103, Leipzig.
Allergic diseases arising in pregnancy may pose a challenge. Skin test results may be influenced by hormonal factors and fetal risk due to the skin testing procedure cannot be excluded. Also, several anti-allergic drugs are not licensed or are even contraindicated in pregnancy. Read More
Hautarzt 2010 Dec;61(12):1014-20
Universitätsklinik für Dermatologie und Venerologie, Medizinische Universität Graz, Auenbruggerplatz 8, 8010, Graz, Österreich.
The specific dermatoses of pregnancy represent a heterogeneous group of inflammatory skin diseases related to pregnancy and/or the postpartum period. The most recent classification includes pemphigoid gestationis, polymorphic eruption of pregnancy, intrahepatic cholestasis of pregnancy, and atopic eruption of pregnancy. The hallmark of all four entities is severe pruritus that is accompanied by characteristic skin changes. Read More
Akush Ginekol (Sofiia) 2008 ;47(6):11-5
Aim: To define clinical presentation and therapy of pruritic urticarial apapules and plaques of pregnancy (PUPPP).
Material And Methods: 20 women between 21 and 34 years of age were included in the present investigation. 16 were primipara and four--multipara. Read More
Dermatol Online J 2008 Nov 15;14(11). Epub 2008 Nov 15.
Department of Dermatology, Columbia University, New York, NY, USA.
Pruritic urticarial papules and plaques of pregnancy (PUPPP) is among the most common dermatoses of pregnancy. Most reports of the effective treatment of PUPPP involve high potency topical corticosteroids or oral steroids. Many authorities have noted cases of PUPPP whose resolution followed parturition. Read More
J Okla State Med Assoc 2008 Jan;101(1):7-11
The University of Oklahoma Department of Dermatology, 619 N.E. 13th Street, OKC, OK 73104, USA.
Context: The dermatoses of pregnancy represent a group of pathologic skin disturbances that cause considerable distress to the gravid patient. It is important to understand the diagnosis, treatment, and implications of these disorders in order to avert unnecessary discomfort and complications.
Objectives: To describe the specific dermatoses of pregnancy according to an established classification system. Read More
Indian J Dermatol Venereol Leprol 2007 Mar-Apr;73(2):141
Department of Dermatology and STD, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry-605 006, India.
Background: During pregnancy profound immunologic, metabolic, endocrine and vascular changes occur, that are responsible for the changes of the skin and its appendages, both physiologic and pathologic.
Aims: We undertook a clinical study to find out the frequency and pattern of skin changes in pregnant women.
Methods: All consecutive pregnant women were included in the study. Read More
Am Fam Physician 2007 Jan;75(2):211-8
Family Medicine Residency Program, Natividad Medical Center, Salinas, California 93912, USA.
Common skin conditions during pregnancy generally can be separated into three categories: hormone-related, preexisting, and pregnancy-specific. Normal hormone changes during pregnancy may cause benign skin conditions including striae gravidarum (stretch marks); hyperpigmentation (e.g. Read More
J Midwifery Womens Health 2007 Jan-Feb;52(1):44-8
Clinical Department of Internal Diseases, Allergology and Clinical Immunology, Medical University of Silesia, Katowice, ul. 3 Maja 13-15, 41-800 Zabrze, Poland.
Pruritic urticarial papules and plaques of pregnancy (PUPPP) are among the most common pruritic dermatoses observed in pregnant women. PUPPP appears most frequently in the third trimester, in primigravidas, and in multiple gestation pregnancies. The eruption of changes occurs initially on the abdomen and extends over the thighs, legs, back, buttocks, arms, and breasts. Read More
Can J Anaesth 2006 Oct;53(10):1010-4
Department of Regional Practice Anesthesiology, Hillcrest Hospital, 6780 Mayfield Road, Mayfield Heights, Ohio 44124, USA.
Purpose: To describe the risk factors for epidural abscess (EA) formation following epidural analgesia in a parturient with pruritic urticarial papules and plaques of pregnancy (PUPPP).
Clinical Features: A 33 yr-old gravida 2 nulliparous patient at 36 weeks gestation presented with severe pre-eclampsia, and PUPPP (treated with prednisone). Magnesium prophylaxis was started and labour was induced. Read More
Ned Tijdschr Geneeskd 2006 Jul;150(28):1549-56
Academisch Medisch Centrum/Universiteit van Amsterdam, afd. Huidziekten, Postbus 22.660, 1100 DD Amsterdam.
Dermatoses related to pregnancy or the postpartum period are known as the specific dermatoses of pregnancy. These dermatoses include (a) pemphigoid gestationis (synonym: herpes gestationis), (b) polymorphic eruption of pregnancy (synonym: pruritic urticarial papules and plaques of pregnancy; PUPPP), (c) prurigo of pregnancy and (d) pruritic folliculitis of pregnancy. Of these disorders, only pemphigoid gestationis has a known cause: an allogeneic immune reaction of the mother to the placental basal membrane. Read More
J Matern Fetal Neonatal Med 2006 May;19(5):305-8
Department of Obstetrics and Gynecology, Faculty of Health Sciences, Soroka University Medical Center, Ben Gurion University of the Negev, Be'er-Sheva, Israel.
Objective: The study was designed to investigate obstetric risk factors and pregnancy outcome of patients with pruritic urticarial papules and plaques of pregnancy (PUPPP).
Methods: A population-based study comparing all pregnancies of women with and without PUPPP was conducted. Deliveries occurred during the years 1988-2002 at the Soroka University Medical Center. Read More
Clin Dermatol 2006 Mar-Apr;24(2):105-8
Dermatology Unit, Kaplan Medical Center, 76100 Rechovot, Israel.
The most commonly diagnosed pruritic dermatosis of pregnancy has a confusing nomenclature. The most commonly term used in the United States is pruritic urticarial papules and plaques of pregnancy (PUPPP), and in Great Britain, since 1982, polymorphic eruption of pregnancy. The etiology of PUPPP is still unknown. Read More
Br J Dermatol 2006 Jan;154(1):54-60
Department of Dermatology, Medical University Graz, Auenbruggerplatz 8, A-8036 Graz, Austria.
Background: Polymorphic eruption of pregnancy (PEP; synonym: pruritic urticarial papules and plaques of pregnancy) is the most common specific dermatosis of pregnancy. However, its clinical characterization is controversial and its pathogenesis uncertain.
Objectives: To evaluate clinical characteristics of and potential trigger factors for PEP in a large mixed ethnic population. Read More
Ginekol Pol 2005 May;76(5):409-13
Instytut Centrum Zdrowia Matki Polki (ICZMP) w Lodzi - Poradnia Dermatologiczna.
The study presents dermatoses specific to the pregnancy period, like intrahepatic cholestasis of pregnancy, pruritic urticarial papules and plaques of pregnancy (PUPPP), impetigo herpetiformis, gestational pemphigoid, papulous and papulo-pustulous dermatitis. Read More
Arch Dermatol 2005 Jun;141(6):705-10
Department of Dermatological Immunopathology, St John's Institute of Dermatology, St Thomas' Hospital, London, England.
Background: Pemphigoid gestationis (PG) is a rare pregnancy-associated subepidermal immunobullous disease that targets hemidesmosomal proteins, particularly BP180. Clinically, PG can resemble the eruption known as polymorphic urticarial papules and plaques of pregnancy (PUPPP), and accurate differentiation between these 2 pruritic pregnancy dermatoses has important implications for fetal and maternal prognoses. Results of epitope mapping studies show that IgG autoantibodies in up to 90% of PG serum samples target the well-defined membrane-proximal NC16a domain of BP180. Read More
Obstet Gynecol 2005 May;105(5 Pt 2):1261-4
Department of Dermatology, Pathology, the University of Texas Southwestern Medical Center at Dallas, Texas, USA.
Background: Pruritic urticarial papules and plaques of pregnancy (PUPPP) is a specific dermatosis of pregnancy common to primigravid women in the third trimester. The rash usually begins on the lower abdomen within striae and spreads to the proximal extremities. Involvement of face, palms, and soles is unusual. Read More
Australas J Dermatol 2005 May;46(2):53-8; quiz 59
Regional Dermatology Centre, Mater Misericordiae Hospital, Dublin, Ireland.
Pruritic urticarial papules and plaques of pregnancy is a common benign dermatosis of pregnancy that was described in 1979 as an intensely pruritic urticarial cutaneous eruption. This is a well-defined clinical entity that mainly occurs in primigravidas in the third trimester, which resolves spontaneously or with delivery and is usually responsive to topical treatments. The aetiology of PUPPP is obscure. Read More
J Reprod Med 2005 Jan;50(1):61-3
Department of Family Practice, Naval Hospital of Jacksonville, 2080 Child Street, Jacksonville, FL 32214, USA.
Background: Pruritic urticarial papules and plaques of pregnancy (PUPPP), also known as polymorphic eruption of pregnancy, is the most common dermatosis of pregnancy. It usually evolves in the third trimester and resolves rapidly postpartum.
Case: A 25-year-old woman complained of an intensely pruritic rash for 2 days. Read More