17,546 results match your criteria Proteus Syndrome


Proteome Profiled in Polymicrobial Urethral Catheter Biofilms.

Proteomes 2018 Dec 9;6(4). Epub 2018 Dec 9.

J. Craig Venter Institute, 9605 Medical Center Drive, Rockville, MD 20850, USA.

, a Gram-positive anaerobic coccoid rod colonizing the human urinary tract, belongs to the taxonomic class of Actinobacteria. We identified as a cohabitant of urethral catheter biofilms (CB). The CBs also harbored more common uropathogens, such as and , supporting the notion that is adapted to a life style in polymicrobial biofilms. Read More

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December 2018

Metal-tolerant endophytic bacteria associated with Silene vulgaris support the Cd and Zn phytoextraction in non-host plants.

Chemosphere 2018 Dec 5;219:250-260. Epub 2018 Dec 5.

Department of Microbiology, University of Silesia in Katowice, Jagiellońska 28, 40-032, Katowice, Poland.

The aim of this study was to isolate and characterise metal-resistant endophytic bacteria from the tissues of Silene vulgaris collected within the vicinity of non-ferrous steelworks in Katowice, Upper Silesia, Southern Poland. Twenty-four strains of metal-resistant endophytic bacteria that belong to 15 genera were isolated from the stems and leaves of Silene vulgaris. Most of these strains showed multiple plant growth-promoting capabilities. Read More

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December 2018

Resistance profile of clinically relevant bacterial isolates against fluoroquinolone in Ethiopia: a systematic review and meta-analysis.

BMC Pharmacol Toxicol 2018 Dec 12;19(1):86. Epub 2018 Dec 12.

Department of Medical Laboratory Sciences, College of Health and Medical Sciences, Haramaya University, P.O.Box 235, Harar, Ethiopia.

Background: Fluoroquinolones are among the most frequently utilized antibacterial agents in developing countries like Ethiopia. Ciprofloxacin has become the most prescribed drug within this class and remains as one of the top three antibacterial agents prescribed in Ethiopia. However, several studies indicated that there is a gradual increase of antibacterial resistance. Read More

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December 2018

Antimicrobial susceptibility patterns of bacteria isolated from patients with ear discharge in Jimma Town, Southwest, Ethiopia.

BMC Ear Nose Throat Disord 2018 4;18:17. Epub 2018 Dec 4.

1School of Medical Laboratory Sciences, Institute of Health, Jimma University, P.O. Box 378, Jimma, Ethiopia.

Background: Otitis media is among the leading causes of childhood illnesses although it can also affect the adults resulting in frequent physician visits, drug prescription and a key contributor to antibiotic resistance. The aim of this study was to determine the risk factors, bacterial profile, and the antimicrobial susceptibility pattern of the isolates from patients with discharging ears which clinically equates to draining otitis media in developing countries with limited medical resources such as otoscope.

Methods: A prospective cross-sectional study was conducted on 173 patients with draining otitis media. Read More

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December 2018

[Surveillance of resistance in the intensive care units using a cumulative antibiogram].

Mikrobiyol Bul 2018 Oct;52(4):329-339

Haydarpaşa Numune Training and Research Hospital, Department of Medical Microbiology, Istanbul, Turkey.

Empiric treatment with broad-spectrum antibiotics exerts condensed pressure in intensive care units (ICUs) for the selection of multidrug-resistant bacteria. Multidrug-resistant gram-negative bacteria became the focus of interest owing to limited treatment options and negative effects on patient survival. Cumulative antibiograms can guide selection of correct empiric treatment, de-escalation treatment according to antibiogram results and development of policies in fight against antibiotic resistance. Read More

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October 2018

Characterisation of plasmid-mediated rmtB-1 in Enterobacteriaceae clinical isolates from São Paulo, Brazil.

Mem Inst Oswaldo Cruz 2018 Dec 10;113(12):e180392. Epub 2018 Dec 10.

Universidade Federal de São Paulo, Escola Paulista de Medicina, Departamento de Medicina Interna, Divisão de Doenças Infecciosas, Laboratório Alerta, São Paulo, SP, Brasil.

OBJECTIVES The emergence of 16S rRNA methyltranferases (16 RMTAses) has jeopardised the clinical use of aminoglycosides. RmtB is one of the most frequently reported in Gram-negatives worldwide. In this study, we aimed to estimate the frequency of 16S RMTAses encoding genes in Enterobacteriaceae isolated in a three-month period from a tertiary Brazilian hospital. Read More

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December 2018

Influence of colonic dialysis using Gubenxiezhuo on the distribution of gut microflora in uremia rats.

J Cell Physiol 2018 Dec 10. Epub 2018 Dec 10.

Department of Nephrology, Minhang Hospital,Fudan University, Shanghai, China.

Objective: This study aimed to explore the underlying function of Gubenxiezhuo dialysis on the distribution of gut microflora uremia.

Methods: A uremia rat model was constructed, and the morphology of renal tissue was determined using the hematoxylin-eosin (H&E) staining. Moreover, the blood samples were collected and the expression of IL-1β, IL-6, and CRP was determined using enzyme-linked immunosorbent assay. Read More

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December 2018

[Susceptibility to first-generation Cephalosporins in Enterobacteriaceae isolated from urine culture according to CLSI and EUCAST breakpoints].

Rev Chilena Infectol 2018 ;35(3):329-331

Clínica Las Condes, Laboratorio de Microbiología, Chile.

Currently, the use of cefazolin is recommended to determine the susceptibility to first-generation oral cephalosporins in strains of enterobacteria in uncomplicated UTI. We determined susceptibility differences to oral cephalosporins in urinary strains according to cefazolin or cefalotin breakpoints and the correlation of susceptibility between cefazolin and cefadroxil. We studied 52 strains with cefalotin and cefazolin by disk-diffusion and MIC (Kirby-Bauer and Vitek XL) and a subgroup by disk-diffusion for cefadroxil. Read More

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January 2018

Prevalence, Risk Factors, and Antibiogram of Bacteria Isolated from Milk of Goats with Subclinical Mastitis in Thika East Subcounty, Kenya.

J Vet Med 2018 11;2018:3801479. Epub 2018 Nov 11.

Department of Animal Sciences, Jomo Kenyatta University of Agriculture and Technology, P.O. Box 62000-00200, Nairobi, Kenya.

A cross-sectional study was carried out to determine the prevalence and risk factors of subclinical mastitis in dairy goats in Thika East Subcounty, Kenya. Further the bacterial pathogens and their antibiogram were investigated. Farm level data on risk factors were obtained from 41 farmers using questionnaires. Read More

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November 2018

Epidemiology of Early-onset Bacterial Neonatal Infections in Madagascar.

Pediatr Infect Dis J 2019 Jan;38(1):76-81

Association Jeremi Rhône-Alpes, Lyon, France.

Background: Little is known about early-onset neonatal bacterial infections (EONBI) in Madagascar. Our aim was to determine their epidemiology to improve their management.

Methods: Inborn neonates at risk for EONBI and admitted in the neonatal unit of 2 tertiary hospitals in Antananarivo, Madagascar, were included in a prospective study from April 2012 to March 2013. Read More

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January 2019

Epidemiology of pathogens causing urinary tract infections in an urban community in southern Brazil.

Braz J Infect Dis 2018 Dec 5. Epub 2018 Dec 5.

Universidade Federal do Paraná, Curso de Farmácia, Departamento de Análises Clínicas, Curitiba, PR, Brazil. Electronic address:

The frequency of urinary tract infection (UTI) and uropathogens in the community was determined by assessing urine culture results of outpatients at a Brazilian public laboratory in a year period. Patients were classified according to sex and age; women were additionally classified considering pregnancy or diabetes. Cultures were considered positive when growing pure cultures with colony counts >10CFU/mL. Read More

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December 2018

Influence of various uropathogens on crystallization of urine mineral components caused by Proteus mirabilis.

Res Microbiol 2018 Dec 3. Epub 2018 Dec 3.

Department of Biology of Bacteria, Faculty of Biology and Environmental Protection, University of Łódź, Banacha 12/16, 90-237 Łódź, Poland. Electronic address:

Infectious urolithiasis is a consequence of long-standing urinary tract infections with urease-positive bacteria, especially Proteus spp. However, because of the often mixed nature of urinary tract infections, in the case of urinary stones formation, several species of bacteria may be involved in the process. The purpose of the study was to determine the impact of the bacterial species: Escherichia coli, Klebsiella pneumoniae, Providencia stuartii, Pseudomonas aeruginosa and Staphylococcus aureus on the crystallization caused by Proteus mirabilis. Read More

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December 2018
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SuperPolymyxin™ Medium for the Screening of Colistin-Resistant Gram-Negative Bacteria in Stool Samples.

Front Microbiol 2018 21;9:2809. Epub 2018 Nov 21.

Institute of Medical Microbiology, University Hospital Münster, Münster, Germany.

Colistin is one of the last resort antimicrobials for the treatment of infections caused by multidrug-resistant Gram-negative bacteria. After the emergence of transferable colistin resistance genes (-1-5), a reliable culture-based screening method to detect colonization with colistin-resistant Gram-negative bacteria (CRGN) is needed. The objective of this study was to test the performance of SuperPolymyxin™ medium to screen for CRGN in stool samples and to compare different methods for the confirmation of colistin resistance (e. Read More

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November 2018

Antibiotic resistance of Enterobacteriaceae causing urinary tract infections in elderly patients living in the community and in the nursing home: a retrospective observational study.

J Antimicrob Chemother 2018 Nov 30. Epub 2018 Nov 30.

Université de Lorraine, APEMAC, F-54000 Nancy, France.

Objectives: Although nursing homes are thought to be significant reservoirs of antibiotic-resistant bacteria, very few large population-based studies comparing antibiotic resistance prevalence in nursing homes and in the community have adjusted for patient characteristics. Our objective was to compare the prevalence of antibiotic resistance of Enterobacteriaceae cultured from urine samples of nursing home residents with that of community-dwelling adults, all aged 65 years or older.

Methods: This study analysed around 20 000 positive urine samples sent to a large laboratory in north-eastern France from 2014 to 2017, collected from individuals aged 65 years or older. Read More

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November 2018
1 Read

Isolation of a Capnophilic and an Extended-Spectrum-β-Lactamase-Producing Proteus mirabilis Isolate with Inability to Grow under pH-Indicator Dyes from the Urine of an Octogenarian Male-Patient with Acute Pyelonephritis.

Jpn J Infect Dis 2018 Nov 30. Epub 2018 Nov 30.

Department of Health and Medical Sciences, Shinshu University Graduate School of Medicine.

A capnophilic Gram-negative rod was recovered from the urine of an octogenarian male patient with acute pyelonephritis. The isolate also demonstrated to produce CTX-M-2-type- extended-spectrum-β-lactamase. Interestingly, the isolate failed to grow on modified Drigalski (BTB) and MacConkey agars even in the CO-enriched atmosphere. Read More

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November 2018
1 Read

Enhanced Antibacterial Activity and Photo-Catalytic Properties of ZnO Nanoparticles: Plant Extract-Assisted Synthesis.

J Nanosci Nanotechnol 2019 May;19(5):2888-2894

Department of Chemistry, Urumu Dhanalakshmi College, Tiruchirappalli 620019, Tamil Nadu, India.

Semiconductor ZnO samples with two different morphologies such as nanoparticles (ZnO-NPs) and nano-sheets (ZnO-NSs) was successfully prepared by microwave heating (MHM) and modified sol-gel (SGM) method, respectively using plant extract as the bio-reducing agent. Structural, purity and morphology of the samples was examined by X-ray powder diffraction (XRD), scanning electron microscopy (SEM) with energy dispersive X-ray (EDX) analysis. Optical property analysis and band gap calculation were carried out by UV-Visible diffuse reflectance (DRS) and photoluminescence (PL) spectroscopy techniques. Read More

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May 2019
1 Read

Selenium Nanoparticle Synthesized by YC801: An Efficacious Pathway for Selenite Biotransformation and Detoxification.

Int J Mol Sci 2018 Nov 29;19(12). Epub 2018 Nov 29.

Key Laboratory of High Magnetic Field and Ion Beam Physical Biology, Hefei Institute of Physical Science, Chinese Academy of Sciences, Hefei 230031, China.

Selenite is extremely biotoxic, and as a result of this, exploitation of microorganisms able to reduce selenite to non-toxic elemental selenium (Se⁰) has attracted great interest. In this study, a bacterial strain exhibiting extreme tolerance to selenite (up to 100 mM) was isolated from the gut of adult and identified as YC801. This strain demonstrated efficient transformation of selenite into red selenium nanoparticles (SeNPs) by reducing nearly 100% of 1. Read More

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November 2018
1 Read

Etiology of Childhood Otorrhea in Luanda, Angola, and a Review of Otitis Media in African Children.

Pediatr Infect Dis J 2018 Dec 3. Epub 2018 Dec 3.

Children's Hospital, Helsinki University Hospital, Helsinki, Finland and University of Helsinki, Helsinki, Finland.

Background: In resource-poor settings, otorrhea causes a significant burden of disease in children. Etiologic studies and structured data on otorrhea and chronic otitis media among African children remain scarce.

Methods: Here, we reviewed 678 bacteriologically analyzed otorrhea samples from Luanda Children's Hospital from children ≤15 years of age between 2008 and 2015. Read More

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December 2018
3 Reads

Emerging antimicrobial resistance among strains in bloodstream infections in Toronto, 2006-2016: a retrospective cohort study.

CMAJ Open 2018 Oct-Dec;6(4):E580-E586. Epub 2018 Dec 3.

Department of Microbiology (Mineau, Kozak, Kissoon, Paterson, Oppedisano, Douri, Gogan, Willey, McGeer, Poutanen), University Health Network/Sinai Health System, Toronto, Ont.; Centre intégré de santé et de services sociaux de Chaudière-Appalaches (Mineau), Sainte-Marie, Que.; Lawrence Park Collegiate Institute (Gogan); Departments of Laboratory Medicine and Pathobiology and of Medicine (McGeer, Poutanen), University of Toronto, Toronto, Ont.

Background: Enterobacteriaceae that produce extended-spectrum β-lactamase (ESBL) have emerged as a serious threat, with variable rates depending on geographic region. We determined the prevalence of ESBL-producing , , and in bloodstream infections in Toronto from 2006 through 2016.

Methods: All patients with , , and isolated from blood in a tertiary care microbiology laboratory in Toronto between 2006 and 2016 (1 isolate per species per patient per year) were included in this retrospective cohort study. Read More

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December 2018
2 Reads

Bacterial and Parasitic Assessment from Fingernails in Debre Markos, Northwest Ethiopia.

Can J Infect Dis Med Microbiol 2018 18;2018:6532014. Epub 2018 Oct 18.

Department of Medical Laboratory Science, College of Medical and Health Sciences, Debre Markos University, Debre Markos, Ethiopia.

Background: Food handlers with untrimmed finger nails could contribute or serve as a vehicle for the transmission of food poisoning pathogens.

Objectives: This study was conducted to determine the prevalence of bacteria and intestinal parasites among food handlers and antibiotic susceptibility profile of the isolated bacteria in Debre Markos University, Ethiopia.

Materials And Methods: This laboratory-based cross-sectional study involved 220 food handlers working in food service establishments in Debre Markos University between 1st January 2015 to 31th June 2016. Read More

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October 2018
7 Reads

Laboratory Diagnosis of Bacterial Vaginosis and Potential Pathogens Other Than Group B Streptococcus in Vaginal Swab of Pregnant Women in Dhaka Medical College Hospital.

Mymensingh Med J 2018 Oct;27(4):834-842

Dr Mst Naznin Tarana, Research Student, Department of Microbiology, Dhaka Medical College, Dhaka, Bangladesh; E-mail:

Pathogenic microorganisms are important cause of maternal and neonatal infections which are transmitted from colonized vagina of mother. The purpose of the present study was to detect the potential pathogens other than Group B Streptococcus in vaginal swab of pregnant women. This prospective cross sectional study was conducted from July 2013 to June 2014 at Dhaka Medical College Hospital, Dhaka, Bangladesh. Read More

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October 2018
1 Read

Multidrug-Resistant Gram-Negative Bacilli: A Retrospective Study of Trends in a Tertiary Healthcare Unit.

Medicina (Kaunas) 2018 Nov 26;54(6). Epub 2018 Nov 26.

"Victor Babeș" University of Medicine and Pharmacy, Eftimie Murgu Street, No. 2, 300041 Timișoara, Romania.

Bacterial multidrug resistance is particularly common in Gram-negative bacilli (GNB), with important clinical consequences regarding their spread and treatment options. The aim of this study was to investigate the trend of multidrug-resistant GNB (MDR-GNB) in high-risk hospital departments, between 2000⁻2015, in intervals of five years, with the intention of improving antibiotic therapy policies and optimising preventive and control practices. This is an observational, retrospective study performed in three departments of the most important tertiary healthcare unit in the southwestern part of Romania: the Intensive Care Unit (ICU), the General Surgery Department (GSD), and the Nutrition and Metabolic Diseases Department (NMDD). Read More

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November 2018
1 Read

The correlation of crystalline and elemental composition of urinary stones with a history of bacterial infections: TXRF, XRPD and PCR-DGGE studies.

Eur Biophys J 2018 Nov 27. Epub 2018 Nov 27.

2nd Department of Urology, Medical University of Lodz, Pabianicka St. 62, 93-513, Łódź, Poland.

The aim of this study was to analyze the correlation between past bacterial infections and the type and chemical composition of urinary stones experienced by human patients. Bacteria have been recognized to contribute to urinary stones; however, the role of uropathogens in the development of specific stones has not been extensively investigated. The detection of past bacterial infection (eleven different bacterial species) in urinary stones from 83 patients was made on a DNA level using polymerase chain reaction (PCR) and denaturing gradient gel electrophoresis (DGGE) and correlated with the chemical composition of urinary stones measured using X-ray powder diffraction (XPRD) technique and their elemental composition by total reflection X-ray fluorescence (TXRF). Read More

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November 2018
3 Reads

Isolation and identification of hyper-ammonia-producing bacteria from commercial fermented skates (Raja kenojei).

J Food Sci Technol 2018 Dec 20;55(12):5082-5090. Epub 2018 Oct 20.

Department of Food Science and Technology and BK 21 Plus Program, Graduate School of Chonnam National University, Gwangju, 61186 South Korea.

Ammonia-producing bacteria were isolated and identified from five commercial fermented skates (A1, A2, A3, A4, and A5). In addition, the pH, ammonia nitrogen, total volatile nitrogen (TVBN), trimethylamine nitrogen (TMAN), and amino nitrogen contents of skate samples were also determined. A total of 88 strains of ammonia-producing bacteria was isolated and seven hyper-ammonia-producing bacteria isolates (A2-2, A2-3, A2-12, A2-18, A2-20, A3-6 and A3-14) were selected based on ammonia nitrogen producing ability. Read More

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December 2018

Phytochemical analysis and antimicrobial activity of aqueous and methanolic extracts of the flowers of Nelumbium speciosum.

Pak J Pharm Sci 2018 Nov;31(6):2429-2434

Faculty of Pharmacy, University of Sargodha, Sargodha, Pakistan.

In present investigation aqueous and methanolic extracts of Nelumbium speciosum flowers were screened for phytochemical constituents and antibacterial activity to ascertain their traditional use. Antimicrobial activity of both extracts was tested by Kirby-Bauer disc diffusion method against four Gram positive strains, viz. Staphylococcus aureus (ATCC25923), Streptococcus agalactiae (13813), Bacillus subtilis (ATCC 6633), Staphylococcus epidermidis (ATCC 12228) and four Gram negative bacterial strains Escherichia coli (ATCC 8739), Pseudomonas aeruginosa (ATCC 27853), Proteus mirabilis (12453) and Klebsiella pneumoniae (10031). Read More

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November 2018
5 Reads

Polymerase Chain Reaction Assay Using the Restriction Fragment Length Polymorphism Technique in the Detection of Prosthetic Joint Infections: A Multi-Centered Study.

J Arthroplasty 2018 Oct 25. Epub 2018 Oct 25.

Department of Molecular Pathology, National Research Institute of Tuberculosis and Lung Diseases, Shahid Behshti University of Medical Sciences, Tehran, Iran; Department of Molecular Biology, Dr. Khosroshahi's Pathobiology Laboratory, Tehran, Iran.

Background: PCR-RFLP (polymerase chain reaction-restriction fragment length polymorphism) techniques have been used for the diagnosis of bacteria in some infections. In this study, we aimed to evaluate the diagnostic accuracy of PCR for the diagnosis of prosthetic joint infections (PJI) and to identify isolated microorganisms, using the RFLP method.

Methods: During January 2015 to January 2018, patients who were suspected of having PJI after arthroplasty surgery or were candidates for revision surgery due to loosening of implant entered the study. Read More

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October 2018
2 Reads

Prevalence and associated factors of urinary tract infections among diabetic patients in Arba Minch Hospital, Arba Minch province, South Ethiopia.

Turk J Urol 2018 Nov 21. Epub 2018 Nov 21.

Department of Medical Laboratory Science, College of Medicine and Health Sciences, Arba Minch University, Arba Minch, Ethiopia.

Objective: Urinary tract infection (UTI) is a common and grave health problem in the world. In fact, patients with diabetes mellitus have an immense risk for developing UTI. The development of resistance among uropathogens to antibiotics is a major crisis which limits the use of drug of choice for the treatment of UTI. Read More

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November 2018
1 Read

The resistomes of six carbapenem-resistant pathogens - a critical genotype-phenotype analysis.

Microb Genom 2018 Nov 21;4(11). Epub 2018 Nov 21.

1​Department of Mathematical Sciences, Chalmers University of Technology, Gothenburg, Sweden.

Carbapenem resistance is a rapidly growing threat to our ability to treat refractory bacterial infections. To understand how carbapenem resistance is mobilized and spread between pathogens, it is important to study the genetic context of the underlying resistance mechanisms. In this study, the resistomes of six clinical carbapenem-resistant isolates of five different species - Acinetobacter baumannii, Escherichia coli, two Klebsiella pneumoniae, Proteus mirabilis and Pseudomonas aeruginosa - were characterized using whole genome sequencing. Read More

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November 2018
8 Reads

Ciprofloxacin Promoted qnrD Expression and Phylogenetic Analysis of qnrD Harboring Plasmids.

Microb Drug Resist 2018 Nov 21. Epub 2018 Nov 21.

1 Institute of Medical Microbiology, Semmelweis University , Budapest, Hungary .

Morganella morganii SE10MM harboring quinolone resistance determinant qnrD was investigated in our study. An entirely sequenced novel 2,662 bp qnrD-plasmid pSE10MM was identified and deposited at GenBank under accession number KU160530. Nucleic acid sequence of pSE10MM showed 94-97% similarity to previously detected qnrD-plasmids of Proteus mirabilis strains. Read More

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November 2018
2 Reads

Antimicrobial susceptibilities of specific syndromes created with organ-specific weighted incidence antibiograms (OSWIA) in patients with intra-abdominal infections.

BMC Infect Dis 2018 Nov 19;18(1):584. Epub 2018 Nov 19.

Department of Hospital Infection Control, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, No. 197 Rui-Jin 2nd Road, Shanghai, 200025, China.

Background: The aim was to evaluate the value of organ-specific weighted incidence antibiogram (OSWIA) percentages for bacterial susceptibilities of Gram-negative bacteria (GNB) collected from intra-abdominal infections (IAIs) during SMART 2010-2014.

Methods: We retrospectively calculated the OSWIA percentages that would have been adequately covered by 12 common antimicrobials based on the bacterial compositions found in the appendix, peritoneum, colon, liver, gall bladder and pancreas.

Results: The ESBL positive rates were 65. Read More

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November 2018
3 Reads

Fabrication of MgO nanostructures and its efficient photocatalytic, antibacterial and anticancer performance.

J Photochem Photobiol B 2018 Nov 12;190:8-20. Epub 2018 Nov 12.

Department of Biotechnology and Genetic Engineering, Bharathidasan University, Tiruchirappali 620 024, Tamilnadu, India.

Magnesium oxide (MgO) nanostructures were prepared using microwave-assisted (M 1) and hydrothermal (M 2) methods and characterized by XRD, SEM and FT-IR. It exhibits cubic structure with an average crystallite size of 20 nm (M 1) and 14 nm (M 2) and the lattice strain (WH plot) is 0.0017 (M 1), 0. Read More

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November 2018
4 Reads

Nitroxoline: an option for the treatment of urinary tract infection with multi-resistant uropathogenic bacteria.

Infection 2018 Nov 17. Epub 2018 Nov 17.

Department of Pneumology, Theresienkrankenhaus, Bassermannstr. 1, 68165, Mannheim, Germany.

The number of multi-resistant uropathogens is increasing. A multi-morbid patient developed a symptomatic urinary tract infection with two multi-resistant bacteria, namely Klebsiella pneumoniae and Proteus mirabilis. Nitroxoline was the only drug active against both uropathogens. Read More

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November 2018
5 Reads

Draft Genome Sequences of Proteus mirabilis K1609 and K670: A Model Strains for Territoriality Examination.

Curr Microbiol 2018 Nov 17. Epub 2018 Nov 17.

Department of Microbiology, Jan Kochanowski University, 15 Swietokrzyska Street, 25-406, Kielce, Poland.

Proteus mirabilis is a pathogenic Gram-negative bacterium characterized by its ability to swarm across surfaces, which frequently leads to colonization of the urinary tract and causes severe infections. P. mirabilis strains are also well known from their self-recognition phenomenon, referred to as Dienes phenomenon. Read More

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November 2018

Protamine-like proteins have bactericidal activity. The first evidence in Mytilus galloprovincialis.

Acta Biochim Pol 2018 11 17. Epub 2018 Nov 17.

Dipartimento di Biologia, Università degli Studi di Napoli Federico II. Napoli, Italy.

The major acid-soluble protein components of the mussel Mytilus galloprovincialis sperm chromatin consist of the protamine-like proteins PL-II, PL-III and PL-IV, an intermediate group of sperm nuclear basic proteins between histones and protamines. The aim of this study was to investigate the bactericidal activity of these proteins since, to date, there are reports on bactericidal activity of protamines and histones, but not on protamine-like proteins. We tested the bactericidal activity of these proteins against Gram-positive bacteria: Enterococcus faecalis and two different strains of Staphylococcus aureus, as well as Gram-negative bacteria: Proteus mirabilis, Proteus vulgaris, Pseudomonas aeruginosa, Salmonella typhmurium, Enterobacter aerogenes, Enterobacter cloacae, and Escherichia coli. Read More

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November 2018
2 Reads

Plantago squarrosa Murray extracts inhibit the growth of some bacterial triggers of autoimmune diseases: GC-MS analysis of an inhibitory extract.

Inflammopharmacology 2018 Nov 16. Epub 2018 Nov 16.

School of Natural Sciences, Nathan Campus, Griffith University, 170 Kessels Rd, Nathan, QLD, 4111, Australia.

Ankylosing spondylitis, multiple sclerosis, rheumatoid arthritis and rheumatic fever are autoimmune inflammatory diseases that may be triggered in genetically susceptible individuals by specific bacterial pathogens. Inhibiting the growth of these bacteria with high antioxidant plant extracts may inhibit the aetiology of these diseases, as well as inhibiting the later phase symptoms. P. Read More

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November 2018
4 Reads

Gene cloning, expression in E. coli, and in vitro refolding of a lipase from Proteus sp. NH 2-2 and its application for biodiesel production.

Biotechnol Lett 2018 Nov 16. Epub 2018 Nov 16.

School of Food and Bioengineering, Zhengzhou University of Light Industry, Zhengzhou, 450001, People's Republic of China.

Objective: To obtain active lipases for biodiesel production by refolding Proteus sp. lipase inclusion bodies expressed in E. coli. Read More

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November 2018
1 Read

Microbial Production of Ethanol From Sludge Derived From an Urban Wastewater Treatment Plant.

Front Microbiol 2018 1;9:2634. Epub 2018 Nov 1.

Department of Microbiology, Institute for Water Research, University of Granada, Granada, Spain.

A collection of lipase-producing microorganisms was isolated from sludge derived from an urban wastewater treatment plant. The microorganisms with the highest levels of lipase activity were selected in order to use triglycerides present in the sludge effectively and were then transformed with genes for the production of ethanol. The transgenic strains showed high growth rates in diluted sludge and produced lipase protein in order to utilize fat present in the sludge, which provides an abundant source of carbon. Read More

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November 2018
6 Reads

Isolation, Characterization, and Quantification of Bacteria from African Sausages Sold in Nairobi County, Kenya.

Int J Food Sci 2018 23;2018:3861265. Epub 2018 Oct 23.

Department of Veterinary Pathology, Microbiology and Parasitology, University of Nairobi, P.O. Box 29053-00625, Nairobi, Kenya.

African sausages are local popular delicacies in Kenya. Demand for these sausages has resulted in this delicacy's vendors being on the increase. However, health risk posed to unsuspecting consumers of African sausages sold in informal, unhygienic make shift road-side kiosks in major cities of Kenya is largely unknown. Read More

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October 2018
3 Reads

In vitro assessment of antimicrobial activity of aqueous and alcoholic extracts of moss (Hedw.) P. Beauv.

Physiol Mol Biol Plants 2018 Nov 27;24(6):1203-1208. Epub 2018 Aug 27.

2Bareilly College, Bareilly, U.P. India.

Bryophytes, the shade loving plants, have tremendous medicinal properties. The aqueous and alcoholic extracts of Hedw. P. Read More

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November 2018
1 Read

The efficacy and safety of tazobactam/ceftolozane in Japanese patients with uncomplicated pyelonephritis and complicated urinary tract infection.

J Infect Chemother 2018 Nov 9. Epub 2018 Nov 9.

Japan Development, MSD K.K., Tokyo, Japan. Electronic address:

We report efficacy and safety results for a combination of a novel cephalosporin class antibiotic and a β-Lactamase inhibitor, tazobactam/ceftolozane (1:2) at a dose of 1.5 g intravenously every 8 h in Japanese patients with uncomplicated pyelonephritis and complicated urinary tract infection. This study design was a nonrandomized, multicenter, open-label trial, and the treatment period was 7 days. Read More

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November 2018
6 Reads

Bacteriostatic and Bactericidal Activity of Deer Musk on Multidrug Resistance Bacteria.

Pak J Biol Sci 2018 Jan;21(7):331-339

Background And Objective: Infecting agents (e.g., bacteria, fungi, virus and parasite) have comprised high levels of multidrug resistance (MDR) with increased morbidity and mortality; so the main aim of this study was to investigate and demonstrate the antimicrobial activity of deer musk on multidrug-resistance bacteria and to proof that musk had a bacteriostatic and bactericidal effects against MDR bacteria. Read More

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January 2018
3 Reads

Analysis of bacteriological pollution and the detection of antibiotic resistance genes of prevailing bacteria emanating from pig farm seepage.

Microbiologyopen 2018 Nov 9:e737. Epub 2018 Nov 9.

Gastro intestinal Microbiology and Biotechnology, Agricultural Research Council- Animal Production, Irene, South Africa.

Management and disposal of pig farm seepage constitute a serious environmental challenge, and seepage discharge from agricultural waste-water is considered to be one of the greatest contributors of organic substances, bacterial pathogens, and antibiotic resistance genes into the environment. The objectives of this study were to assess the level of bacteriological pollution and to identify the resident antibiotic-resistant genes of culturable bacteria from a studied pig farm seepage. Enumeration of the viable bacterial cell of plated bacteria suspensions (10 to 10  cfu/mL) was performed; also, identification of pure bacterial colonies was done using an API 20E bacterial identification kit. Read More

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November 2018
17 Reads

Identification of AGI1-A, a variant of Acinetobacter genomic island 1 (AGI1), in a French clinical isolate belonging to the Enterobacter cloacae complex.

J Antimicrob Chemother 2018 Nov 8. Epub 2018 Nov 8.

Laboratory of Bacteriology, University Hospital of Dijon, Plateau technique de Biologie, BP 37013, Dijon cedex, France.

Objectives: To characterize the structure of a variant of Acinetobacter genomic island 1 (AGI1) in the Enterobacter cloacae clinical isolate EclC2185 responsible for an 8 year outbreak in Dijon University Hospital.

Methods: The genome was sequenced (Miseq) and de novo assembled (Velvet). PCR and Sanger sequencing were performed to determine the sequence of the genomic island. Read More

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November 2018
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Identification of small molecule compounds active against Staphylococcus aureus and Proteus mirabilis.

Biochem Biophys Res Commun 2018 Dec 5;506(4):1047-1051. Epub 2018 Nov 5.

Institute of Immunology and Experimental Therapy of the Polish Academy of Science, Department of Immunology of Infectious Diseases, ul. R. Weigla 12, 53-114, Wroclaw, Poland.

Staphylococcus aureus is a human pathogen rapidly becoming a serious health problem due to ease of acquiring antibiotic resistance. To help identify potential new drug candidates effective against the pathogen, a small focused library was screened for inhibition of bacterial growth against several pathogens, including S. aureus. Read More

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December 2018
6 Reads

Miransertib (ARQ 092), an orally-available, selective Akt inhibitor is effective against Leishmania.

PLoS One 2018 6;13(11):e0206920. Epub 2018 Nov 6.

Department of Medicine, Division of Infectious Diseases, University of British Columbia, Vancouver, BC, Canada.

Leishmaniasis is amongst the most important neglected diseases, afflicting more than 12 million people in 88 countries. There is an urgent need for safe orally bioavailable and cost-effective drugs for the treatment of leishmaniasis. It has recently been shown that Leishmania activates host macrophage serine/threonine kinase Akt, to promote survival of both parasites and infected cells. Read More

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November 2018
6 Reads

Complications of percutaneous nephrostomy in a district general hospital.

Turk J Urol 2018 Nov;44(6):478-483

Department of Urology, Countess of Chester Hospital, Chester, UK.

Objective: Percutaneous nephrostomy (PCN) is one of the commonest procedures performed. There are currently no European recommendations on the accepted rate of complications. The aim of the present study is to report the complication rate of PCN with the specific emphasis on sepsis and septic shock, the causative organisms, sensitivities to antibiotics, and associated risk factors. Read More

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November 2018
8 Reads

Rates of Antibiotic Resistance / Sensitivity in Bacterial Cultures of Hidradenitis Suppurativa Patients.

J Eur Acad Dermatol Venereol 2018 Nov 5. Epub 2018 Nov 5.

Department of Medical Sciences Section of Dermatology, University of Ferrara, Italy.

Background: Antibiotic (AB) treatment is one of the first steps in the management of Hidradenitis Suppurativa (HS). Bacteria, in HS patients, may play a double role, as triggering factors of inflammatory reactions and/or agents of infection.

Objectives: The aims of this study are: 1) to assess prevalence and AB resistance of bacterial growths in HS patients 2) assessment of the clinical relevance of obtained data in guiding the selection of the most effective AB therapy. Read More

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November 2018
12 Reads

The antibacterial effect of peritoneal fluid in experimental peritonitis.

Ulus Travma Acil Cerrahi Derg 2018 Sep;24(5):387-390

Department of General Surgery, University of Health Sciences, İstanbul Fatih Sultan Mehmet Training and Research Hospital, İstanbul-Turkey.

Background: In our study, the effects of peritoneal fluid on some Gram-negative and Candida albicans in experimental peritonitis rats were studied. The primary objective of the present study was to understand the effect of peritoneal fluid on microorganisms causing intra-abdominal infections.

Methods: Twenty male Sprague-Dawley rats weighing between 250 and 300 g were used in the study. Read More

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September 2018
4 Reads

Flagellar motility plays important role in Biofilm formation of Bacillus cereus and Yersinia enterocolitica.

Pak J Pharm Sci 2018 Sep;31(5(Supplementary)):2047-2052

Department of Zoology, Govt. College University, Lahore, Pakistan.

Bacteria live either independently as planktonic cells or in organized surface associated colonies called as biofilms. Biofilms play an important role in increased pathogenesis of bacteria and it is assumed that motility is one of the contributing factors towards biofilm initiation. This study was planned to identify the role of flagella in biofilm formation by constructing flagellated (wild type) and physically disrupted variants (non-motile). Read More

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September 2018
2 Reads

Green biosynthesis of silver nanoparticles produced from marine Streptomyces sp. Al-Dhabi-89 and their potential applications against wound infection and drug resistant clinical pathogens.

J Photochem Photobiol B 2018 Dec 14;189:176-184. Epub 2018 Sep 14.

Addiriyah Chair for Environmental Studies, Department of Botany and Microbiology, College of Sciences, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia.

Green biosynthesis of nanoparticles yielded from the extracellular metabolites of marine derived actinomycetes is covering enormous attention due to their superior applications and broad spectrum of bioactive secondary metabolites. The present study aimed to explore the characterization of novel bioactive Streptomyces sp. Al-Dhabi-89 derived from the Arabian Gulf region of Dammam was authenticated based on their physiological, biochemical characterization and molecular level amplification of the 16S rRNA was guided for the green biosynthesis of silver nanoparticles from the cell free extract. Read More

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December 2018
3 Reads
2.960 Impact Factor