7,145 results match your criteria Proteus Infections


Evolution of the Antimicrobial resistance of Bacteria causing Urinary Tract Infections.

Comb Chem High Throughput Screen 2021 Jun 22. Epub 2021 Jun 22.

Basic Science Department, College of Medicine, Hawler Medical University, Erbil, Kurdistan Region. Iraq.

Background: The bacteria, Escherichia coli (E. coli) and Klebsiella pneumoniae (K. pneumoniae), are the main reasons for urinary tract infections (UTIs). Read More

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[Antibiotic resistance and antibiotic consumption in a region - using the example of community-acquired urinary tract infections].

Aktuelle Urol 2021 Jun 16. Epub 2021 Jun 16.

Universitätsklinikum Gießen und Marburg GmbH, Klinik für Urologie, Kinderurologie und Andrologie, Gießen.

Background:  In sight of increasing bacterial resistances, appropriate and cautious antibiotic therapy (antibiotic stewardship) is becoming more and more important, in private practices as well. A current S3 guideline is available for the treatment of uncomplicated urinary tract infections, which recommends that regular epidemiological examinations of pathogen sensitivity are to be carried out promptly and locally. With this said, the antibiotic prescriptions of the resident doctors in Hesse were examined and compared with the sensitivity of the most important pathogens causing urinary tract infections. Read More

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Antibiotic Stewardship for Canine and Feline Acute Urinary Tract Infection: An Observational Study in a Small Animal Hospital in Northwest Italy.

Antibiotics (Basel) 2021 May 11;10(5). Epub 2021 May 11.

Department of Veterinary Science, University of Turin, 10095 Grugliasco, TO, Italy.

Antimicrobial stewardship programs (ASPs) have been suggested to reduce antimicrobial resistance phenomena in veterinary medicine, as antibiotics are commonly used without microbiological confirmation. The aim of the present study is to design a specific working flow for a tailored antimicrobial treatment in the case of canine and feline urinary tract infections (UTIs). Urine samples were collected by cystocentesis from 16 dogs and 12 cats presenting acute signs of UTI. Read More

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Proteus mirabilis thoracic vertebral osteomyelitis: a case report.

J Med Case Rep 2021 May 28;15(1):274. Epub 2021 May 28.

Division of Infectious Diseases, Shuang-Ho Hospital, Taipei Medical University, No. 291, Zhongzheng Rd., Zhonghe Dist., New Taipei City, 235, Taiwan.

Background: Proteus mirabilis is the second most common pathogen that causes urinary tract infections after Escherichia coli. In rare cases, it is associated with vertebral osteomyelitis. The underlying mechanism of this relationship may be related to the retrograde dissemination of bacteria through the paravertebral venous plexus. Read More

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Biosynthesis of silver nano-drug using and its synergistic antibacterial activity against multidrug-resistant bacteria for wound dressing applications.

3 Biotech 2021 Jun 8;11(6):255. Epub 2021 May 8.

Department of Biotechnology, College of Science, Taif University, P.O. Box 11099, Taif, 21944 Saudi Arabia.

We report here the synthesis of silver nanoparticles (AgNPs) from an aqueous extract of and their use as an antimicrobial agent on their own or in combination with antibiotics in inhibiting multidrug-resistant bacteria (MDR). One strategy of bacterial infection control in wound healing is AgNP biosynthesis. We collected bacterial strains of patient skin infections from Al-Adwani Hospital. Read More

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Colistin Resistance among Isolated from Clinical Samples in Gaza Strip.

Can J Infect Dis Med Microbiol 2021 20;2021:6634684. Epub 2021 Apr 20.

Department of Medical Laboratory Sciences Faculty of Health Sciences Islamic University of Gaza, Gaza Strip, Gaza, Palestine, State of Palestine.

Bacterial infections, especially drug-resistant infections, are a major global health issue. The emergence of multidrug-resistant (MDR) strains of and the lack of new antibiotics have worrisome prospects for all of humanity. Colistin is considered the last-line drug for MDR Gram-negative bacteria (GNB), and it is often used for treatment of respiratory infections caused by MDR-GNB. Read More

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Activity of Fosfomycin and Nitrofurantoin Against Contemporary Pathogens Isolated from Indian Tertiary Care Hospitals.

Microb Drug Resist 2021 May 13;27(5):678-684. Epub 2020 Oct 13.

Wockhardt Research Centre, D4 MIDC, Aurangabad, India.

In India, multidrug resistance in community and hospital associated Gram-negative pathogens has increased sharply over the past few years. In the absence of novel oral multidrug resistant-pathogen active therapies, the therapeutic situation with regard to community infections is even more challenging. Hence, the focus is now shifting toward potentially expanding the utility of older antibiotics such as fosfomycin and nitrofurantoin beyond their approved pathogen coverage. Read More

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Detection of Extended-Spectrum Beta-Lactamase-Producing and Carbapenem-Resistant Bacteria from Mink Feces and Feed in the United States.

Foodborne Pathog Dis 2021 May 11:1-10. Epub 2021 May 11.

Utah Water Research Laboratory, Department of Civil and Environmental Engineering, Utah State University, Logan, Utah, USA.

Antibiotic-resistant infections caused by extended-spectrum β-lactamases (ESBLs) and carbapenemases are increasing worldwide. Bacteria resistant to extended-spectrum cephalosporins and last resort carbapenems have been reported from food animals and their environments. Other concentrated nonfood-producing animals such as mink farming can be a reservoir of bacteria resistant to these critically important antibiotics. Read More

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Bacterial profile and antimicrobial susceptibility patterns of isolates among patients diagnosed with surgical site infection at a tertiary teaching hospital in Ethiopia: a prospective cohort study.

Ann Clin Microbiol Antimicrob 2021 May 10;20(1):33. Epub 2021 May 10.

Department of Clinical Pharmacy, School of Pharmacy, Institute of Health, Jimma University, Jimma, Ethiopia.

Background: Globally, surgical site infections are the most reported healthcare-associated infection and common surgical complication. In developing countries such as Ethiopia, there is a paucity of published reports on the microbiologic profile and resistance patterns of an isolates.

Objective: This study aimed at assessing the bacterial profile and antimicrobial susceptibility patterns of isolates among patients diagnosed with surgical site infection at Jimma Medical Center in Ethiopia. Read More

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Antimicrobial susceptibility of bacterial isolates from urinary tract infections in companion animals in Spain.

Vet Rec 2021 05 28;188(9):e60. Epub 2021 Jan 28.

Catalan Wildlife Service, Centre de Fauna Salvatge de Torreferrussa, Barcelona, Spain.

Background: The increasing emergence of multidrug-resistant bacteria, causing urinary tract infections (UTI) in dogs and cats, represents a great therapeutic challenge and a public health concern.

Methods: Laboratory records of 4943 urinary microbiological diagnosis results and antimicrobial resistance profiles of suspected UTI cases in dogs and cats were analysed from 2016 to 2018 in Spain.

Results: This study showed a higher percentage of positive microbiological diagnoses in dogs (42%, 1368/3270) than in cats (27%, 457/1673). Read More

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atpD gene sequencing, multidrug resistance traits, virulence-determinants, and antimicrobial resistance genes of emerging XDR and MDR-Proteus mirabilis.

Sci Rep 2021 May 4;11(1):9476. Epub 2021 May 4.

Department of Bacteriology, Immunology, and Mycology, Faculty of Veterinary Medicine, Suez Canal University, Ismailia, 41522, Egypt.

Proteus mirabilis is a common opportunistic pathogen causing severe illness in humans and animals. To determine the prevalence, antibiogram, biofilm-formation, screening of virulence, and antimicrobial resistance genes in P. mirabilis isolates from ducks; 240 samples were obtained from apparently healthy and diseased ducks from private farms in Port-Said Province, Egypt. Read More

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Prevalence and Outcomes of Multi-Drug Resistant Blood Stream Infections Among Nursing Home Residents Admitted to an Acute Care Hospital.

J Intensive Care Med 2021 May 3:8850666211014450. Epub 2021 May 3.

8405MedStar Washington Hospital Center, Washington, DC, USA.

Objective: The prevalence of multi-drug resistant organism (MDRO) colonization in nursing home residents has been well documented, but little is known about the impact of MDRO bloodstream infections (BSIs). The aim of this study was to assess the prevalence, cost, and outcomes of MDRO-BSI vs. non-MDRO-BSI among nursing home residents. Read More

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Antibiotic Resistance of Uropathogens Isolated from Patients Hospitalized in District Hospital in Central Poland in 2020.

Antibiotics (Basel) 2021 Apr 16;10(4). Epub 2021 Apr 16.

Institute of Biological Sciences, Faculty of Exact and Natural Sciences, Siedlce University of Natural Sciences and Humanities, 14 Bolesława Prusa Str., 08-110 Siedlce, Poland.

The aim of this study was to determine antibiotic resistance patterns and the prevalence of uropathogenes causing urinary tract infections (UTIs) in patients hospitalized in January-June 2020 in central Poland. Antimicrobial susceptibility testing was performed using the disk-diffusion method. (52. Read More

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First Description of the Composition and the Functional Capabilities of the Skin Microbial Community Accompanying Severe Scabies Infestation in Humans.

Microorganisms 2021 Apr 23;9(5). Epub 2021 Apr 23.

Scabies Laboratory, Infectious Diseases Program, Biology Department, QIMR Berghofer Medical Research Institute, Brisbane 4006, Australia.

Epidemiological studies link infection and impetigo. Scabies mites can promote (Group A ) and infections by breaching the skin barrier and excreting molecules that inhibit host innate immune responses. However, little is known about the composition and the function of the scabies-associated microbiota. Read More

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Bacteriophage therapy for inhibition of multi drug-resistant uropathogenic bacteria: a narrative review.

Ann Clin Microbiol Antimicrob 2021 Apr 26;20(1):30. Epub 2021 Apr 26.

Department of Microbiology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.

Multi-Drug Resistant (MDR) uropathogenic bacteria have increased in number in recent years and the development of new treatment options for the corresponding infections has become a major challenge in the field of medicine. In this respect, recent studies have proposed bacteriophage (phage) therapy as a potential alternative against MDR Urinary Tract Infections (UTI) because the resistance mechanism of phages differs from that of antibiotics and few side effects have been reported for them. Escherichia coli, Klebsiella pneumoniae, and Proteus mirabilis are the most common uropathogenic bacteria against which phage therapy has been used. Read More

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Microbial profile, antimicrobial resistance, and molecular characterization of diabetic foot infections in a university hospital.

Germs 2021 Mar 15;11(1):39-51. Epub 2021 Mar 15.

MD, Internal Medicine Department (Unit of Diabetes & Metabolism), Faculty of Medicine, Alexandria University, 21512, Egypt.

Introduction: Diabetic foot infections (DFIs) are among the most severe complications of diabetes. The aim of this study was to determine the etiological pathogens of DFIs in different Wagner's and IDSA/IWGDF grades, and to assess their antimicrobial susceptibility pattern together with molecular characterization of antibiotic resistance genes.

Methods: A prospective study was conducted on 120 DFI patients at Main Alexandria University Hospital, Egypt. Read More

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Clinical evaluation of the acuitas® AMR gene panel for rapid detection of bacteria and genotypic antibiotic resistance determinants.

Diagn Microbiol Infect Dis 2021 Mar 26;100(4):115383. Epub 2021 Mar 26.

OpGen, Inc., Gaithersburg, MD, USA.

Urinary tract infections are leading causes of hospital admissions. Accurate and timely diagnosis is important due to increasing morbidity and mortality from antimicrobial resistance. We evaluated a polymerase chain reaction test (Acuitas AMR Gene Panel with the Acuitas Lighthouse Software) for detection of 5 common uropathogens (Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, Pseudomonas aeruginosa, Enterococcus faecalis) and antibiotic resistance genes directly from urine for prediction of phenotypic resistance. Read More

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[Utility of the blood culture in infection of the urinary tract with fever in the elderly].

Rev Esp Quimioter 2021 Jun 15;34(3):249-253. Epub 2021 Apr 15.

Moncef Belhassen Garcia, Servicio de Medicina Interna. Sección de Enfermedades Infecciosas. CAUSA. IBSAL. CIETUS, Universidad de Salamanca. Paseo San Vicente 58-182, 37007, Salamanca, Spain.

Objective: Urinary tract infections are one of the most common community infections. The diagnosis of urinary infections in the elderly is complex because of its presentation and clinic. The aim of this article is to evaluate the usefulness of blood cultures in febrile urinary tract infection in elderly patients, risk factors, causes of discordance between urine and blood cultures, usefulness of biomarkers and mortality. Read More

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-Related Infections and their Significance: A 9-Year Retrospective Study.

J Microsc Ultrastruct 2021 Jan-Mar;9(1):18-25. Epub 2020 Nov 9.

Department of Internal Medicine, Saint Vincent Hospital, Worcester, Massachusetts, USA.

Introduction: is a Gram-positive, catalase- and oxidase-negative, microaerophilic, nonmotile bacteria species rarely associated with human infections such as arthritis, bacteremia, endocarditis, and meningitis. The bacteria are also often confused with streptococci species or treated as a contaminant.

Patients And Methodology: We conducted a retrospective, observational cohort study on all patients with isolates in blood samples from July 2010 to June 2019. Read More

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November 2020

Antimicrobial drug resistance profile of isolated bacteria in dogs and cats with urologic problems at Chiang Mai University Veterinary Teaching Hospital, Thailand (2012-2016).

Zoonoses Public Health 2021 Apr 12. Epub 2021 Apr 12.

Faculty of Veterinary Medicine, Chiang Mai University, Chiang Mai, Thailand.

The present study aimed to estimate the proportion of bacterial urinary tract infection (UTI) in dogs and cats, assess risks associated with bacterial UTI, and to determine bacterial isolates' antimicrobial susceptibility and resistance pattern from the urinary tract of dogs and cats with urologic problems. The medical records from animals visiting Chiang Mai University Small Animal Veterinary Teaching Hospital between January 2012 and December 2016 were reviewed. In total, 203 dogs and 49 cats with urinary tract diseases that had samples submitted for bacterial culture were identified;198 and 24 bacterial isolates were recovered from dogs' and cats' submitted samples, respectively. Read More

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Draft Genome of Serogroup O18 Elaborating Phosphocholine-Decorated O Antigen.

Front Cell Infect Microbiol 2021 25;11:620010. Epub 2021 Mar 25.

Institute of Biology, Jan Kochanowski University in Kielce, Kielce, Poland.

is a pathogenic, Gram-negative, rod-shaped bacterium that causes ascending urinary tract infections. Swarming motility, urease production, biofilm formation, and the properties of its lipopolysaccharide (LPS) are all factors that contribute to the virulence of this bacterium. Uniquely, members of the O18 serogroup elaborate LPS molecules capped with O antigen polymers built of pentasaccharide repeats; these repeats are modified with a phosphocholine (ChoP) moiety attached to the proximal sugar of each O unit. Read More

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Quick Identification and Differentiation of Proteus spp. by PCR and RFLP Along with Their Antibiotic Resistance Pattern.

Mymensingh Med J 2021 Apr;30(2):355-361

Dr Hasnatul Jannat, Assistant Surgeon, Mymensingh Medical College Hospital, Mymensingh, Bangladesh; E-mail:

Different Proteus species are encountered in human infections and may vary with the type of infections they cause. So, the present study was conducted to detect species of Proteus by PCR and RFLP along with their antibiotic resistance pattern. This cross-sectional study was conducted in the Department of Microbiology of Dhaka Medical College, Dhaka, Bangladesh, from July 2018 to June 2019. Read More

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[The problem of antibiotic resistance in patients with urinary tract infection].

Urologiia 2021 Mar(1):5-12

Pirogov Russian National Research Medical University, Moscow, Russia.

Objective: To analyze the incidence and resistance of microorganisms to antibacterial drugs isolated in urine cultures of patients with urinary tract infections from 2012 to 2019.

Materials And Methods: In the Pirogov City Clinical Hospital No1 and in the Bauman City Clinical Hospital No 29 analyzed the results of 15083 urine cultures in 12554 patients from 2012 to 2019.

Results: Enterococcus faecalis (41%), Escherichia coli (36. Read More

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VAGINAL CUFF INFECTION AFTER HYSTERECTOMY IN UKRAINE.

Wiad Lek 2021 ;74(2):196-201

NATIONAL PIROGOV MEMORIAL MEDICAL UNIVERSITY, VINNYTSYA, UKRAINE.

Objective: The aim: To obtain the first estimates of the current prevalence of vaginal cuff infection after hysterectomy and antimicrobial resistance of causing pathogens in Ukraine.

Patients And Methods: Materials and methods: We performed a retrospective multicenter cohort study was based on surveillance data. The study population consisted of women who had an abdominal, vaginal or laparoscopic hysterectomy from 2017 to 2019 in 7 women hospitals of Ukraine. Read More

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Effects of Bovine Colostrum with or without Egg on In Vitro Bacterial-Induced Intestinal Damage with Relevance for SIBO and Infectious Diarrhea.

Nutrients 2021 Mar 22;13(3). Epub 2021 Mar 22.

Centre of Immunobiology, Blizard Institute, Barts and The London School of Medicine, Queen Mary, University of London, London E1 2AT, UK.

Small intestinal bacterial overgrowth (SIBO) occurs commonly, is difficult to treat, and frequently recurs. Bovine colostrum (BC) and chicken eggs contain immunoglobulins and other components that possess antimicrobial, immunoregulatory, and growth factor activities; however, it is not known if they have the ability to reduce injury caused by the presence of bacteria associated with SIBO (, , , , , , and ) and infectious diarrhea (enteropathogenic , ). We examined the effects of BC, egg, or the combination, on bacterial growth and bacteria-induced changes in transepithelial electrical resistance (TEER) and bacterial translocation across confluent Caco-2 monolayers. Read More

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Indole Derivatives Obtained from Egyptian sp. Soil Isolates Exhibit Antivirulence Activities against Uropathogenic .

Antibiotics (Basel) 2021 Mar 29;10(4). Epub 2021 Mar 29.

Department of Microbiology and Immunology, Faculty of Pharmacy, Cairo University, Cairo 11562, Egypt.

is a frequent cause of catheter associated urinary tract infections (CAUTIs). Several virulence factors contribute to its pathogenesis, but swarming motility, biofilm formation, and urease activity are considered the hallmarks. The increased prevalence in antibiotic resistance among uropathogens is alarming and requires searching for new treatment alternatives. Read More

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Use of MALDI-TOF for identification and surveillance of gram-negative bacteria in captive wild psittacines.

Braz J Biol 2021 29;82:e233523. Epub 2021 Mar 29.

Universidade de São Paulo - USP, Departamento de Patologia da Faculdade de Medicina Veterinária e Zootecnia, São Paulo, SP, Brasil.

Microbiological studies of the sanitary and health status of psittacine birds that will be reintroduced is important in evaluating whether these animals act as carriers of pathogenic agents to other animals and humans. Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) is a faster and more accurate method to identify bacteria than conventional microbiology methods. The aim of this study was to evaluate the health status of psittacines housed in captivity, by assessment of Gram-negative bacteria from fecal microbiota through MALDI- TOF MS identification. Read More

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Does washing medical devices before and after use decrease bacterial contamination?: An in vitro study.

Medicine (Baltimore) 2021 Apr;100(13):e25285

Department of Pathology, Botucatu Medical School, São Paulo State University (UNESP), Botucatu, SP, Brazil.

Abstract: Surface treatment of medical devices may be a way of avoiding the need for replacement of these devices and the comorbidities associated with infection. The aim of this study was to evaluate whether pre- and postcontamination washing of 2 prostheses with different textures can decrease bacterial contamination.The following microorganisms were evaluated: Staphylococcus aureus, Staphylococcus epidermidis, Proteus mirabilis and Enterococcus faecalis. Read More

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CT as a Diagnostic Tool for Emphysematous Pyelitis: A Case Report.

Cureus 2021 Feb 23;13(2):e13513. Epub 2021 Feb 23.

Radiology, Dr. Ajmera Diagnostic, New Delhi, IND.

Gas forming infections of the renal collecting system occurs because of organisms like Escherichia coli, Klebsiella, and Proteus. If the gas is restricted to the collecting system, without causing involvement of the cortex, it is called emphysematous pyelitis; whereas, invasion and penetration of the cortex imply a more gruesome diagnosis of emphysematous pyelonephritis. A 59-year-old male patient, previously diagnosed with a large right renal calculus and having multiple co-morbidities presented to the surgery department with right flank pain; Double J (DJ) stenting was done to relieve the pain from colic due to obstructive renal calculi; the patient subsequently discharged without any post-procedural complications. Read More

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February 2021