6,965 results match your criteria Proteus Infections


Broad-Spectrum Cephalosporin-Resistant and/or Fluoroquinolone-Resistant Associated with Canine and Feline Urogenital Infections.

Antibiotics (Basel) 2020 Jul 7;9(7). Epub 2020 Jul 7.

Institute of Microbiology, University of Veterinary Medicine, 1210 Vienna, Austria.

The aim of the present study was to characterize resistant to 3rd and 4th generation cephalosporins, carbapenems and/or fluoroquinolones, isolated from dogs and cats with urogenital infections. In total, 36 strains ( ( = 28), ( = 3), , , , and (each = 1)) were included in the present study, 28 from Austria and 8 from Serbia. Isolates were characterized by a polyphasic approach including susceptibility pheno- and genotyping and microarray-based assays. Read More

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http://dx.doi.org/10.3390/antibiotics9070387DOI Listing

Antimicrobial and Antibiofilm Activities of Probiotic Lactobacilli on Antibiotic-Resistant .

Microorganisms 2020 Jun 26;8(6). Epub 2020 Jun 26.

Department of Biological Sciences, College of Arts and Sciences, University of South Florida St. Petersburg, St. Petersburg, FL 33701, USA.

The emergence of biofilm-forming, multi-drug-resistant (MDR) infections is a serious threat that necessitates non-antibiotic therapies. Antibiotic susceptibility and biofilm-forming activity of isolates from urine samples were assessed by disc diffusion and crystal violet assays, respectively. Antimicrobial activities of probiotic by crystal violet assays. Read More

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http://dx.doi.org/10.3390/microorganisms8060960DOI Listing

Attenuation of Proteus mirabilis colonization and swarming motility on indwelling urinary catheter by antibiofilm impregnation: An in vitro study.

Colloids Surf B Biointerfaces 2020 Jun 18;194:111207. Epub 2020 Jun 18.

Department of Biotechnology, Alagappa University, Karaikudi, India. Electronic address:

Proteus mirabilis is one of the important etiologic agents of urinary tract infections (UTI), which complicates the long-term urinary catheterization process in clinical settings. Owing to its crystalline biofilm forming ability and flagellar motility, elimination of P. mirabilis from urinary system becomes very difficult. Read More

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http://dx.doi.org/10.1016/j.colsurfb.2020.111207DOI Listing

An outbreak of acute skin and soft tissue infections including necrotizing fasciitis in Kalwala village, India, 2018: Public health implications for the lymphatic filariasis elimination program.

Trans R Soc Trop Med Hyg 2020 Jun 20. Epub 2020 Jun 20.

National Centre for Disease Control, Ministry of Health and Family Welfare, New Delhi, India.

Background: A cluster of 15 acute skin and soft tissue infections (SSTIs), including two cases of necrotizing fasciitis, reported in July 2018 from Kalwala village, led us to investigate and describe their epidemiology and to provide recommendations.

Methods: Cases, defined as localized painful swelling and redness in Kalwala residents from 1 December 2017 to 20 August 2018, were identified from hospital records and house-to-house surveys. We conducted an unmatched case-control study to identify risk factors for severity. Read More

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http://dx.doi.org/10.1093/trstmh/traa046DOI Listing

Bacterial spectrum and antibiotic resistance of urinary tract infections in patients treated for upper urinary tract calculi: a multicenter analysis.

Eur J Clin Microbiol Infect Dis 2020 Jun 16. Epub 2020 Jun 16.

Urology School, University of Milan, Milan, Italy.

The purpose of this study is to collect information on the bacterial resistance to antibiotics of bacteria isolated from urine cultures of patients treated for upper urinary tract calculi. Data of patients with urinary tract infection and urolithiasis were retrospectively reviewed to collect information on age, gender, stone size, location, hydronephrosis, procedure of stone removal and antibiotic treatment, identification and susceptibility of pathogens, symptoms, and infectious complications. A total of 912 patients from 11 centers in 7 countries (Bulgaria, Greece, Italy, North Macedonia, Spain, and Turkey) were studied. Read More

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http://dx.doi.org/10.1007/s10096-020-03947-zDOI Listing

A Systematic Review on Drug Resistant Urinary Tract Infection Among Pregnant Women in Developing Countries in Africa and Asia; 2005-2016.

Infect Drug Resist 2020 18;13:1465-1477. Epub 2020 May 18.

Department of Medical Microbiology and Immunology, Division of Biomedical Sciences, School of Medicine, College of Health Sciences, Mekelle University, Mekelle, 1871, Ethiopia.

Background: Urinary tract infection is one of the most common health problems during pregnancy. It is most commonly reported among pregnant women and is a known reason of morbidity during pregnancy worldwide, predominantly in developing countries. The etiological agents include and others. Read More

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http://dx.doi.org/10.2147/IDR.S250654DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245001PMC

Multilocus sequence analysis for the taxonomic updating and identification of the genus Proteus and reclassification of Proteus genospecies 5 O'Hara et al. 2000, Proteus cibarius Hyun et al. 2016 as later heterotypic synonyms of Proteus terrae Behrendt et al. 2015.

BMC Microbiol 2020 Jun 10;20(1):152. Epub 2020 Jun 10.

National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention (China CDC), State Key Laboratory of Infectious Disease Prevention and Control, Changbai Road 155, Changping, Beijing, 102206, China.

Background: Members of the genus Proteus are mostly opportunistic pathogens that cause a variety of infections in humans. The molecular evolutionary characteristics and genetic relationships among Proteus species have not been elucidated to date. In this study, we developed a multilocus sequence analysis (MLSA) approach based on five housekeeping genes (HKGs) to delineate phylogenetic relationships of species within the genus Proteus. Read More

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http://dx.doi.org/10.1186/s12866-020-01844-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288399PMC

Epidemiologic changes in bloodstream infections in Andalucía (Spain) during the last decade.

Clin Microbiol Infect 2020 May 26. Epub 2020 May 26.

Unidad Clínica de Enfermedades Infecciosas, Microbiología y Medicina Preventiva, Hospital Universitario Virgen Macarena/Departamento de Medicina, Universidad de Sevilla/Instituto de Biomedicina de Sevilla, Sevilla, Spain.

Objectives: During the last decade, some changes in the epidemiology of invasive infections have been reported; however, specific studies with patient-level data are scarce. The aim of this study was to describe and evaluate the epidemiologic changes in bloodstream infections (BSI) during the last decade in Andalucía, Spain.

Methods: Data from two prospective cohorts of BSI in adults with the same methodology performed 10 years apart in 11 hospitals (eight tertiary and three community) in Andalucía, Spain, were compared; the 2006-7 cohort study was performed between October 2006 and March 2007, and the 2016-17 cohort study was performed between October 2016 and March 2017. Read More

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http://dx.doi.org/10.1016/j.cmi.2020.05.015DOI Listing

Comparing the Bacteriostatic Effects of Different Metal Nanoparticles Against Proteus vulgaris.

Curr Microbiol 2020 May 28. Epub 2020 May 28.

Department of Biotechnology, Urmia Branch, Islamic Azad University, Urmia, Iran.

For many years, researchers were looking for new antibacterial substances to deal with hospital infections and especially resistant infections. Nanoparticles attracted much attentions because of their very small size that increases the surface to capacity ratio and consequently increase chemical activity. In this study, the antibacterial effects of silver, copper oxide, nickel oxide, and titanium dioxide nanoparticles were studied on Proteus vulgaris, as a bacterium involved in the resistant hospital infections. Read More

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http://dx.doi.org/10.1007/s00284-020-02029-9DOI Listing

Natural Cyanobacterial Polymer-Based Coating as a Preventive Strategy to Avoid Catheter-Associated Urinary Tract Infections.

Mar Drugs 2020 May 26;18(6). Epub 2020 May 26.

i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Rua Alfredo Allen, 208, 4200-135 Porto, Portugal.

Catheter-associated urinary tract infections (CAUTIs) represent about 40% of all healthcare-associated infections. Herein, the authors report the further development of an infection preventive anti-adhesive coating (CyanoCoating) meant for urinary catheters, and based on a natural polymer released by a marine cyanobacterium. CyanoCoating performance was assessed against relevant CAUTI etiological agents, namely Escherichia coli, Proteus mirabilis, Klebsiella pneumoniae, methicillin resistant Staphylococcus aureus (MRSA), and Candida albicans in the presence of culture medium or artificial urine, and under biofilm promoting settings. Read More

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http://dx.doi.org/10.3390/md18060279DOI Listing
May 2020
2.853 Impact Factor

Transposon Insertion Site Sequencing of Providencia stuartii: Essential Genes, Fitness Factors for Catheter-Associated Urinary Tract Infection, and the Impact of Polymicrobial Infection on Fitness Requirements.

mSphere 2020 May 27;5(3). Epub 2020 May 27.

Department of Microbiology and Immunology, Jacobs School of Medicine and Biomedical Sciences, State University of New York at Buffalo, Buffalo, New York, USA

is a common cause of polymicrobial catheter-associated urinary tract infection (CAUTI), and yet literature describing the molecular mechanisms of its pathogenesis is limited. To identify factors important for colonization during single-species infection and during polymicrobial infection with a common cocolonizer, , we created a saturating library of ∼50,000 transposon mutants and conducted transposon insertion site sequencing (Tn-Seq) in a murine model of CAUTI. strain BE2467 carries 4,398 genes, 521 of which were identified as essential for growth in laboratory medium and therefore could not be assessed for contribution to infection. Read More

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http://dx.doi.org/10.1128/mSphere.00412-20DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7253602PMC

Trends in Distribution and Antibiotic Resistance of Bacteria Isolated from Urine Cultures of Children in Northern Israel Between 2010 and 2017.

Microb Drug Resist 2020 May 14. Epub 2020 May 14.

The Azrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel.

To identify the changing trends of uropathogens over the years 2010-2017 and examine the incidence of both antibiotic resistance and extended spectrum beta lactamases (ESBL)-producing Enterobacteriaceae in urine cultures from pediatric patients. Electronic medical records of 1,056 children, admitted to the Poriya Medical Center in Israel, between 2010 and 2017 with positive urine cultures, were reviewed for bacterial species and antibiotics resistance. The leading pathogen was (76%), followed by (7%), (5. Read More

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http://dx.doi.org/10.1089/mdr.2020.0111DOI Listing

Burn wound microbiology and the antibiotic susceptibility patterns of bacterial isolates in three burn units of Abbottabad, Pakistan.

J Burn Care Res 2020 May 13. Epub 2020 May 13.

Department of Microbiology, Abbottabad University of Science and Technology, Havelian , Abbottabad, Pakistan.

Infection is the leading cause of morbidity and mortality among burn patients and is accentuated multifold by the emergence of antimicrobial resistance among the nosocomial isolates. It is vital to know the common organisms involved in infected burn wound etiology and their respective antibiotic susceptibility patterns. These crucial findings can help in formulating a better and more efficient antimicrobial therapy plan for controlling burn wound infections. Read More

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http://dx.doi.org/10.1093/jbcr/iraa073DOI Listing

Postpartum mastitis in the breastfeeding women and antimicrobial resistance of responsible pathogens in ukraine: results a multicenter study.

Wiad Lek 2020 ;73(5):895-903

Brovarska Multidisciplinary District Hospital, Brovary, Ukraine.

Objective: The aim: To obtain the prevalence of mastitis in the breastfeeding women and antimicrobial resistance of responsible pathogens in Ukraine.

Patients And Methods: Materials and methods: A retrospective multicenter cohort study was based on surveillance data for Postpartum Mastitis and included 18,427 breastfeeding women's who gave birth in 11 regional hospitals of Ukraine.

Results: Results: 22. Read More

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January 2020

Evaluation of inhibitory activity of domestic probiotics for against invasion and infection by Proteus mirabilis in the urinary tract.

J Infect Dev Ctries 2020 Apr 30;14(4):366-372. Epub 2020 Apr 30.

Department of Culinary Arts, Hungkuo Delin University of Technology, New Taipei City, Taiwan.

Introduction: Approximately 5% of men and 40%-50% of women have experienced urinary tract infections (UTI), which are the most common infectious diseases and nosocomial infections in humans. Proteus mirabilis is susceptible to most antibiotics, but antibiotic treatment usually causes side effects. In this research, lactic acid bacteria (LAB) was assessed for its inhibitory activity against a urinary tract pathogen. Read More

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http://dx.doi.org/10.3855/jidc.12203DOI Listing

Comparative Effectiveness of Antibiotic Treatment Duration in Children With Pyelonephritis.

JAMA Netw Open 2020 May 1;3(5):e203951. Epub 2020 May 1.

Department of Pediatrics, The Johns Hopkins University School of Medicine, Baltimore, Maryland.

Importance: National guidelines recommend treating children with pyelonephritis for 7 to 14 days of antibiotic therapy, yet data are lacking to suggest a more precise treatment duration.

Objective: To compare the clinical outcomes of children receiving a short-course vs a prolonged-course of antibiotic treatment for pyelonephritis.

Design, Setting, And Participants: Retrospective observational study using inverse probability of treatment weighted propensity score analysis of data from 5 hospitals in Maryland between July 1, 2016, and October 1, 2018. Read More

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http://dx.doi.org/10.1001/jamanetworkopen.2020.3951DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7199115PMC

Distribution of blaTEM, blaSHV, blaCTX-M, blaOXA, and blaDHA in Proteus mirabilis Isolated from Diabetic Foot Infections in Erbil, Iraq.

Cell Mol Biol (Noisy-le-grand) 2020 Apr 20;66(1):88-94. Epub 2020 Apr 20.

College of Science, Salahaddin University, Erbil, Kurdistan Region-Iraq.

Diabetic foot infection is considered to be one of the most important medical, economic, and social problems and a major cause of morbidity and mortality. Proteus mirabilis is a common etiologic agent of diabetic foot infections. This study aimed to determine the prevalence of beta-lactamase genes in P. Read More

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Frugal filtering optical lenses for point-of-care diagnostics.

Biomed Opt Express 2020 Apr 9;11(4):1864-1875. Epub 2020 Mar 9.

EPSRC Proteus IRC Hub in Optical Molecular Sensing and Imaging, Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, EH16 4TJ, UK.

Infectious diseases are the leading cause of morbidity and mortality in low and middle income countries (LMICs). Rapid diagnosis of infections in LMICs presents many challenges, especially in rural areas where access to health care, including diagnostics, is poor. Microscopy is one of the most commonly used platforms to diagnose bacterial infections on clinical samples. Read More

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http://dx.doi.org/10.1364/BOE.381014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7173883PMC

Biofilm-producing potential of urinary pathogens isolated from chronic and recurrent urinary tract infections and impact of biofilm on gentamicin and colistin in vitro efficacy.

Epidemiol Mikrobiol Imunol 2020 ;69(1):3-9

Aim: The presented study was to compare in vitro biofilm production by bacterial strains from chronic/recurrent and from acute non-complicated UTIs. The activity of gentamicin and colistin on biofilm form of these strains has also been detected, with goal to predict the gentamicin and colistin therapeutic efficacy in the antimicrobial treatment of patients with a suspected presence of biofilm in urinary tract.

Material And Methods: The group of 40 bacterial strains repeatedly isolated from patients with chronic or recurrent UTIs was compared with the group of 40 strains from acute UTIs. Read More

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[Aerobic bacteria from skin lesions in reptiles and their antimicrobial susceptibility].

Tierarztl Prax Ausg K Kleintiere Heimtiere 2020 Apr 23;48(2):78-88. Epub 2020 Apr 23.

LABOKLIN GmbH & Co. KG, Bad Kissingen.

Objective: Bacterial skin infections are common in reptiles. Although many such infections are influenced by multifactorial problems, specific treatment of bacterial infections is an important consideration. The objective of this study was to evaluate the range of aerobic bacteria in skin lesions of reptiles and to determine their antimicrobial susceptibility. Read More

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http://dx.doi.org/10.1055/a-1115-7907DOI Listing

anti-biofilm activity of bacteriocin from a marine sp. strain Sh10 against .

Iran J Microbiol 2020 Feb;12(1):52-61

Department of Environmental Science and Natural Resources, Faculty of Science and Technology, University Kebangsaan Malaysia, Selangor, Malaysia.

Background And Objectives: Biofilm formed by strains is one of the most important medical problems especially in the case of device-related urinary tract infections. This study was conducted to evaluate the bacteriocin produced by a marine isolate of sp. Sh10, for it's inhibitory activity against pre-formed biofilm and in interference with the biofilm-forming of two biofilm-producing bacteria ( UCa4 and UCe1). Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7163041PMC
February 2020

Antimicrobial susceptibility and distribution of extended-spectrum β-lactamases, AmpC β-lactamases and carbapenemases among Proteus, Providencia and Morganella isolated from global hospitalised patients with intra-abdominal and urinary tract infections: Results of the Study for Monitoring Antimicrobial Resistance Trends (SMART), 2008-2011.

J Glob Antimicrob Resist 2020 Apr 18;22:398-407. Epub 2020 Apr 18.

Department of Internal Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan; Department of Laboratory Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan. Electronic address:

Objectives: The increasing trend of β-lactam resistance among Enterobacteriaceae is a worldwide problem. This study investigated isolates of the tribe Proteeae (Proteus, Providencia and Morganella) causing intra-abdominal and urinary tract infections from the worldwide Study for Monitoring Antimicrobial Resistance Trends (SMART) collected from 2008-2011.

Methods: Antimicrobial susceptibility testing was performed on isolates with an ertapenem minimum inhibitory concentration >0. Read More

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http://dx.doi.org/10.1016/j.jgar.2020.04.011DOI Listing

Effects of Cefazolin and Meropenem in Eradication Biofilms of Clinical and Environmental Isolates of Proteus mirabilis.

Curr Microbiol 2020 Aug 16;77(8):1681-1688. Epub 2020 Apr 16.

Departamento de Bioquímica, Centro de Biociências - Universidade Federal de Pernambuco, Av. Moraes Rego s/n, Recife, PE, Brazil.

Proteus mirabilis is an opportunistic Gram-negative bacterium belonging to the family Enterobacteriaceae and is known for its ability to cause urinary tract infections. The aim of this study was to determine the value of the minimum concentration of cefazolin and meropenem on biofilm eradication, as well as the resistance profiles and genetic diversity of clinical and environmental isolates of P. mirabilis. Read More

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http://dx.doi.org/10.1007/s00284-020-01984-7DOI Listing

Culture and PCR based detection of bacteria causing urinary tract infection in urine specimen.

Pak J Med Sci 2020 Mar-Apr;36(3):391-395

Mohammad Din, M.Phil. Pathology Department, Bolan University of Medical and Health Sciences, Quetta, Pakistan.

Objectives: Urinary tract infections are the second most common bacterial infections occurring at all ages and both sexes. The increasing rate of antibiotic resistance is a global concern. The use of routinely used antibiotics is resulting in treatment failure. Read More

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http://dx.doi.org/10.12669/pjms.36.3.1577DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150396PMC

Antibiotic resistance and sensitivity pattern of Metallo-β-Lactamase Producing Gram-Negative Bacilli in ventilator-associated pneumonia in the intensive care unit of a public medical school hospital in Bangladesh.

Hosp Pract (1995) 2020 May 6:1-9. Epub 2020 May 6.

Faculty of Medicine and Defense Health, Universiti Pertahanan Nasional Malaysia (National Defense University of Malaysia), Kem Sungai Besi, Kuala Lumpur, Malaysia.

: Ventilator-associated pneumonia (VAP) is the most common nosocomial infection in intensive care units (ICU), accounting for 25% of all ICU infections. Antimicrobial resistance is increasing and becoming a significant health problem worldwide, increasing hospital length of stay, mortality and costs. Identifying antibiotic resistance patterns in VAP is important as this can cause outbreaks in ICUs. Read More

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http://dx.doi.org/10.1080/21548331.2020.1754687DOI Listing

Antibiotic resistance pattern of Escherichia coli isolates from outpatients with urinary tract infections in Somalia.

J Infect Dev Ctries 2020 Mar 31;14(3):284-289. Epub 2020 Mar 31.

Faculty of Medicine and Health Sciences, Jamhuriya University of Science and Technology, Mogadishu, Somalia.

Introduction: Several studies suggest increasing rates of antibiotic resistance among adult populations with Urinary tract infections (UTI). Escherichia coli (E. coli), is the predominant bacterium both in the community and in hospital environments causing uropathogenic infections. Read More

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http://dx.doi.org/10.3855/jidc.12189DOI Listing

[Evaluation of compliance with the antibiotic prophylaxis protocol in hysterectomy. Prospective cohort study].

Rev Esp Quimioter 2020 Jun 31;33(3):180-186. Epub 2020 Mar 31.

Gil Rodríguez-Caravaca, Unidad de Medicina Preventiva, Hospital Universitario Fundación Alcorcón C/ Budapest 1, 28922 Alcorcón (Madrid). Spain.

Objective: Health care-related infections are a public health problem, among them surgical site infection (SSI) are the most frequent in hospitals. The objetive of this study was to assess the effect of the compliance to antibiotic prophylaxis protocol on the incidence of surgical site infection in hysterectomized patients.

Methods: A prospective cohort study was carried out between October 2009 and December 2018. Read More

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http://dx.doi.org/10.37201/req/098.2019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7262387PMC

[Virusuria as a component of the urine microbiota and its significance for assessing the health of the urinary tract: a descriptive clinical study].

Urologiia 2020 Mar(1):12-18

Rostov State Medical University, Rostov-on-Don, Russia.

Aim: To determine the frequency of occurrence of oportunistic pathogenic bacterial flora and viral pathogens in the urine of healthy people with the establishment of the association between them.

Materials And Methods: 40 healthy sexually active women and men were examined, which are divided by gender into equivalent groups: Group I - healthy women (n=19), Group II - healthy men (n=21). The age of the subjects ranged from 20 to 25 years, the average age was 22. Read More

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Phytochemical screening, antioxidant and antibacterial properties of daphne mucronata.

J Tradit Chin Med 2019 12;39(6):764-771

Centre of Biotechnology and Microbiology, University of Peshawar, Peshawar 25000, Pakistan.

Objective: To aim at preliminary phytochemical screening of Daphne mucronata and evaluate its antioxidant and antibacterial activities.

Methods: Preliminary phytochemical screening was conducted for the crude extracts using standard methods. Antioxidant properties of crude methanolic extracts, n-hexane, chloroform, ethyl acetate and aqueous fractions of leaves, roots and bark were evaluated following standard procedures. Read More

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December 2019
0.667 Impact Factor

Bacterial otitis media in sub-Saharan Africa: a systematic review and meta-analysis.

BMC Infect Dis 2020 Mar 17;20(1):225. Epub 2020 Mar 17.

Department of Medical Laboratory Sciences, College of Health and Medical Sciences, Haramaya University, P.O.Box, 235, Harar, Ethiopia.

Background: Otitis media is inflammation of the middle ear, comprising a spectrum of diseases. It is the commonest episode of infection in children, which often occurs after an acute upper respiratory tract infection. Otitis media is ranked as the second most important cause of hearing loss and the fifth global burden of disease with a higher incidence in developing worlds like Sub-Saharan Africa and South Asia. Read More

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http://dx.doi.org/10.1186/s12879-020-4950-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077006PMC
March 2020
2.613 Impact Factor

[The state and role of esophagus, stomach, intestinal microbiota in patients with ulcer disease, chronic gastritis, esophagitis.]

Klin Lab Diagn 2020 ;65(1):42-49

Tver State Medical University, 170100, Tver, Russia.

The microflora of 64 biopsies taken during fibrogastroduodenoscopy of the mucous membrane of the esophagus, stomach and duodenum in healthy volunteers and 1120 samples obtained from the same parts of the digestive tract in patients with esophagitis, chronic gastritis and peptic ulcer disease were studied. The patients ranged in age from 18 to 62 years. Traditional bacteriological method was used to isolate and identify microorganisms. Read More

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http://dx.doi.org/10.18821/0869-2084-2020-65-1-42-49DOI Listing

Genetics of Acquired Antibiotic Resistance Genes in spp.

Front Microbiol 2020 21;11:256. Epub 2020 Feb 21.

EA7361 "Structure, dynamic, function and expression of broad spectrum β-lactamases", LabEx Lermit, Faculty of Medicine, Université Paris-Saclay, Le Kremlin-Bicêtre, France.

spp. are commensal Enterobacterales of the human digestive tract. At the same time, is commonly involved in urinary tract infections (UTI). Read More

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http://dx.doi.org/10.3389/fmicb.2020.00256DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7046756PMC
February 2020

Transcriptome Analysis of Two Strains of Proteus mirabilis with Swarming Migration Deficiency Isolated from Patients with Urinary Tract Infection.

Curr Microbiol 2020 Aug 9;77(8):1381-1389. Epub 2020 Mar 9.

Department of Clinical Laboratory, The Fifth Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510700, Guangdong, China.

Two rare strains of Proteus mirabilis with swarming migration deficiency were isolated from urine samples of two patients with urinary tract infections and were named as G121 and G137. Migration experiments showed that P. mirabilis HI4320 had typical migration on blood agar, while G121 and G137 had significantly weakened migration ability. Read More

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http://dx.doi.org/10.1007/s00284-020-01931-6DOI Listing
August 2020
1.423 Impact Factor

Surveillance of antibiotic resistance among uropathogens in Aljouf region northern Saudi Arabia.

Iran J Microbiol 2019 Dec;11(6):468-477

Department of Microbiology, Microbiology Laboratory, Prince Mutaib Hospital, Sakaka, Saudi Arabia.

Background And Objectives: Urinary tract infections are common health problem affecting millions worldwide. Antibiotic resistance among uropathogens (Ups) is prevalent in many countries. In the absence of any available data in the region, this hospital-based study investigated the pattern, frequency and susceptibility of Ups at Prince Mutaib Bin Abdulaziz Hospital, Aljouf Region, Saudi Arabia. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048966PMC
December 2019

Multi-drug resistant bacteria predict mortality in bloodstream infection in a tertiary setting in Tanzania.

PLoS One 2020 4;15(3):e0220424. Epub 2020 Mar 4.

Department of Microbiology and Immunology, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania.

Background: Bloodstream infections (BSI) are serious and life-threatening, associated with high mortality and morbidity. In resource-limited settings, there is a paucity of data on predictors of outcome in patients with BSI. This study aimed at examining the predictors of mortality in patients with BSI as well as bacteria causing BSI. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0220424PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7055912PMC

Genome analysis of enterobacteriaceae with non-wild type susceptibility to third-generation cephalosporins recovered from diseased dogs and cats in Europe.

Vet Microbiol 2020 Mar 1;242:108601. Epub 2020 Feb 1.

Hygiène Hospitalière, CHU Besançon, France; Université de Bourgogne Franche-Comté, UMR CNRS Chrono-environnement, Besançon, France; Bioinformatique et big data au service de la santé, UFR Santé, Université de Bourgogne Franche-Comté, Besançon, France. Electronic address:

Background: Extended-spectrum-β-lactamases (ESBL) and plasmid-mediated cephalosporinases (pAmpC)-producing Enterobacteriaceae isolates are now reported worldwide in humans, animals, and in the environment. We identified the determinants of resistance to β-lactams and associated resistance genes as well as phylogenetic diversity of 53 ESBL- or pAmpC-producing Enterobacteriaceae isolated from dogs and cats in Europe.

Materials/methods: Of a collection of 842 Enterobacteriaceae isolates that were recovered in 2013 and 2014 from 842 diseased and untreated dogs and cats, for 242 ampicillin or amoxicillin resistant isolates (MIC ≥ 16 mg/L), cefotaxime (CTX) and ceftazidime (CAZ) MICs were determined. Read More

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http://dx.doi.org/10.1016/j.vetmic.2020.108601DOI Listing

Phytochemical analyses and antibacterial activities of Erodium, Euphorbia, Logoecia and Tamarix species.

J Infect Dev Ctries 2019 11 30;13(11):1013-1020. Epub 2019 Nov 30.

Hamdi Mango Research Center for Scientific Research, The University of Jordan, Amman, Jordan.

Introduction: Resistance against commonly used antibacterial agents has become a globally recognized threat to human health. Therefore, the development of new and effective antibacterial agents is necessary to treat infections caused by resistant bacterial strains; plants are a promising source of new agents to be tested.

Methodology: The minimum inhibitory concentrations (MIC) of ethanolic extracts of Erodium gruinum, Euphorbia hierosolymitana, Logoecia cuminoides, and Tamarix tetragyna against 10 Gram-negative and 5 Gram-positive bacteria were determined using agar well diffusion and microtiter plate dilution methods, respectively. Read More

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http://dx.doi.org/10.3855/jidc.11776DOI Listing
November 2019

Infection in Mice Reduces Protective Gut Microbiota, Augmenting Disease Pathways.

Front Microbiol 2020 30;11:73. Epub 2020 Jan 30.

Department of Wine, Food and Molecular Biosciences, Faculty of Agriculture and Life Sciences, Lincoln University, Lincoln, New Zealand.

(Vp), a major food-borne pathogen, is responsible for severe infections such as gastroenteritis and septicemia, which may be accompanied by life-threatening complications. While studies have evaluated factors that affect the virulence of the pathogen, none have investigated the interaction of Vp with gut microbiota. To address this knowledge gap, we compared the effect of Vp on gut bacterial community structure, immunity, liver and kidney function, in pseudo germ-free (PGF) mice and normal (control) mice. Read More

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http://dx.doi.org/10.3389/fmicb.2020.00073DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7002474PMC
January 2020
3.941 Impact Factor

The third national Japanese antimicrobial susceptibility pattern surveillance program: Bacterial isolates from complicated urinary tract infection patients.

J Infect Chemother 2020 May 17;26(5):418-428. Epub 2020 Feb 17.

Department of Urology, National Hospital Organization Kure Medical Center, Hiroshima, Japan.

The antimicrobial susceptibility patterns of bacterial pathogens isolated from patients with complicated urinary tract infections were analyzed using national surveillance data. The data consisted of 881 bacterial strains from eight clinically relevant species. The data were collected for the third national surveillance project from January 2015 to March 2016 by the Japanese Society of Chemotherapy, the Japanese Association for Infectious Disease, and the Japanese Society of Clinical Microbiology. Read More

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http://dx.doi.org/10.1016/j.jiac.2020.01.004DOI Listing

Surveillance of Omadacycline Activity Tested against Clinical Isolates from the United States and Europe: Report from the SENTRY Antimicrobial Surveillance Program, 2016 to 2018.

Antimicrob Agents Chemother 2020 04 21;64(5). Epub 2020 Apr 21.

JMI Laboratories, North Liberty, Iowa, USA.

Omadacycline is a broad-spectrum aminomethylcycline approved in October 2018 by the U.S. Food and Drug Administration for treating acute bacterial skin and skin structure infections and community-acquired pneumonia as both an oral and intravenous once-daily formulation. Read More

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http://dx.doi.org/10.1128/AAC.02488-19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7179604PMC

Hospital-specific antibiograms and antibiotic prophylaxis for prostate biopsies: a reexamination of AUA recommendations.

Can J Urol 2020 Feb;27(1):10099-10104

Department of Urology, Sidney Kimmel Cancer Center, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, USA.

Introduction: To assess whether standard American Urological Association (AUA) and other recommendations for prostate biopsy prophylaxis provide sufficient coverage of common urinary organisms responsible for post biopsy infections by comparing local antibiograms in Philadelphia-area hospitals.

Materials And Methods: De-identified culture results derived from antibiograms were collected from six academic and community hospitals in the Philadelphia region. Analysis specifically focused on four major bacterial causes of urinary tract infection following prostate biopsy (Escherichia coli (E. Read More

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February 2020

Localization of acute pyelonephritis in pyrexia of unknown origin using FDG PET/CT.

Asia Ocean J Nucl Med Biol 2020 ;8(1):79-83

SPECT Lab, Nuclear Medicine Services, Pune, Maharashtra, India.

Objectives: Acute pyelonephritis presents with high-grade fever, dysuria, flank pain, leukocytosis, and microscopic hematuria. Urine culture aids in the diagnosis of this infection. It can be complicated or uncomplicated. Read More

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http://dx.doi.org/10.22038/aojnmb.2019.14242DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6994777PMC
January 2020

outcompetes in artificial urine medium through secretion of ammonia and other volatile compounds.

Heliyon 2020 Feb 5;6(2):e03361. Epub 2020 Feb 5.

Laboratorio de Patogénesis Bacteriana, Departamento de Investigaciones Bioquimicas y Farmaceuticas, Centro de Estudios Biomédicos, Basicos, Aplicados y Desarrollo (CEBBAD), Universidad Maimónides, Hidalgo 775, C1405BCK, Buenos Aires, Argentina.

and form mixed biofilms in catheter-associated urinary tract infections. However, co-inoculation of with in artificial urine medium (AUM) resulted in a drastic reduction of cells in both biofilm and planktonic growth. Here, the mechanism behind this competitive interaction was studied. Read More

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http://dx.doi.org/10.1016/j.heliyon.2020.e03361DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005574PMC
February 2020

Characterization of Resistance in Gram-Negative Urinary Isolates Using Existing and Novel Indicators of Clinical Relevance: A 10-Year Data Analysis.

Life (Basel) 2020 Feb 11;10(2). Epub 2020 Feb 11.

Institute of Clinical Microbiology, Faculty of Medicine, University of Szeged, 6725 Szeged, Semmelweis utca 6., Hungary.

Classical resistance classifications (multidrug resistance [MDR], extensive drug resistance [XDR], pan-drug resistance [PDR]) are very useful for epidemiological purposes, however, they may not correlate well with clinical outcomes, therefore, several novel classification criteria (e.g., usual drug resistance [UDR], difficult-to-treat resistance [DTR]) were introduced for Gram-negative bacteria in recent years. Read More

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http://dx.doi.org/10.3390/life10020016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7175163PMC
February 2020

Reply to An et al.

Am J Physiol Renal Physiol 2020 02;318(2):F507-F508

Division of Urology, Department of Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, China.

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http://dx.doi.org/10.1152/ajprenal.00016.2020DOI Listing
February 2020

Occurrence and Characteristics of Mobile Colistin Resistance () Gene-Containing Isolates from the Environment: A Review.

Int J Environ Res Public Health 2020 02 6;17(3). Epub 2020 Feb 6.

Department of Veterinary Public Health and Preventive Medicine, University of Nigeria, Nsukka 400001, Nigeria.

The emergence and spread of mobile colistin (COL) resistance () genes jeopardize the efficacy of COL, a last resort antibiotic for treating deadly infections. COL has been used in livestock for decades globally. Bacteria have mobilized genes (-1 to -9). Read More

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http://dx.doi.org/10.3390/ijerph17031028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7036836PMC
February 2020
2.063 Impact Factor

First-time characterization of viable but non-culturable Proteus mirabilis: Induction and resuscitation.

J Cell Mol Med 2020 Mar 7;24(5):2791-2801. Epub 2020 Feb 7.

Department of Biological Sciences, College of Arts and Sciences, University of South Florida St. Petersburg, St. Petersburg, Florida.

Pathogenic bacteria can enter into a viable but non-culturable (VBNC) state under unfavourable conditions. Proteus mirabilis is responsible for dire clinical consequences including septicaemia, urinary tract infections and pneumonia, but is not a species previously known to enter VBNC state. We suggested that stress-induced P. Read More

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http://dx.doi.org/10.1111/jcmm.15031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077546PMC

Antimicrobial profiling and molecular characterization of antibiotic resistant genes of Proteus vulgaris isolated from tertiary care hospital, Islamabad, Pakistan.

Pak J Pharm Sci 2019 Nov;32(6(Supplementary)):2887-2891

Institute of Microbiology, University of Agriculture, Faisalabad, Pakistan.

Urinary tract infections (UTIs) are among the most common bacterial infections acquired from hospitals and community. Pseudomonas and Proteus species are the common cause of these UTIs. Generally, UTIs are self-limiting but have potential to re-occur. Read More

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November 2019