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Arq Gastroenterol 2020 Apr-Jun;57(2):178-181

Universidade de São Paulo, Faculdade de Saúde Pública, São Paulo, SP, Brasil.

Background: Poor appetite is common through the aging process and increases the risk of weight loss, protein-energy malnutrition, immunossupression, sarcopenia and frailty. The Simplified Nutritional Appetite Questionnaire (SNAQ) has the aim to monitor appetite and identify older adults at risk of weight loss.

Objective: To describe the process of translation and cultural adaptation to Brazilian Portuguese of the SNAQ. Read More

Clin Nutr 2020 Jun 9. Epub 2020 Jun 9.

Center for Nutrition and Bowel Disease, Department of Gastroenterology, Aalborg University Hospital, Mølleparkvej 4, 9000, Aalborg, Denmark; Department of Clinical Medicine, Faculty of Medicine, Aalborg University, Sdr. Skovvej 5, 9000, Aalborg, Denmark.

Background: Wasting of body mass and skeletal muscle frequently develops in patients with cancer and is associated with impaired functional ability and poor clinical outcome and quality of life. This study aimed to evaluate the feasibility and explore the effect of a multimodal intervention targeting nutritional status in patients with non-small cell lung cancer receiving primary anti-neoplastic treatment. Additionally, predictive and prognostic factors of gaining skeletal muscle were explored. Read More

Int J Older People Nurs 2020 Jun 29:e12332. Epub 2020 Jun 29.

Faculty of Medicine, Institute of Health and Society, University of Oslo, Oslo, Norway.

Aims And Objectives: This study investigated older adults' experiences of using the Appetitus app with support from healthcare professionals.

Background: Good nutrition status is important for good health when ageing. However, as undernutrition remains a prevalent and persistent problem among older adults, the study explored whether technology affords innovative support for nutritional self-care among older adults. Read More

Physiol Rep 2020 Jun;8(12):e14498

Department of Animal Science, Faculty of Technical Sciences, Aarhus University, Tjele, Denmark.

The aim was to test the hypothesis that prenatal under- and overnutrition in late gestation can program small intestinal (SI) growth, angiogenesis, and endocrine function to predispose for a hyperabsorptive state, thereby increasing the susceptibility to the adverse effects of an early postnatal obesogenic diet. Twin-pregnant ewes were exposed to adequate (NORM), LOW (50% of NORM), or HIGH (150% energy and 110% protein of NORM) diets through the last trimester (term ~147 days). From 3 days to 6 months of age, their lambs were fed either a moderate (CONV) or a high-carbohydrate high-fat (HCHF) diet. Read More

World J Gastroenterol 2020 Jun;26(22):2916-2930

The Liver Unit, Queen Elizabeth Hospital Birmingham, Birmingham B15 2GW, United Kingdom.

Malnutrition encompassing both macro- and micro-nutrient deficiency, remains one of the most frequent complications of alcohol-related liver disease (ArLD). Protein-energy malnutrition can cause significant complications including sarcopenia, frailty and immunodepression in cirrhotic patients. Malnutrition reduces patient's survival and negatively affects the quality of life of individuals with ArLD. Read More

Mol Nutr Food Res 2020 Jun 24:e1900835. Epub 2020 Jun 24.

Micalis Institute, Université Paris-Saclay, INRAE, AgroParisTech, Jouy-en-Josas, 78350, France.

Scope: Protein malnutrition is characterized by stunted growth, hepatic steatosis and a damaged gut mucosal architecture. Since high-fat shaped gut microbiota (HFM) has an increased ability in providing nutrients and energy from food to the host, the aim of this study is to determine whether such a microbiota could beneficially impact on the consequences of malnutrition.

Methods And Results: The cecal content of specific pathogen free C57Bl/6J mice fed a high-fat diet or a low-protein diet is transplanted in two groups of germ-free C57Bl/6J recipient mice, which are subsequently fed a low-protein diet for 8 weeks. Read More

Nutr Clin Pract 2020 Jun 24. Epub 2020 Jun 24.

Department of Human Biology, School of Nutrition and Translational Research in Metabolism (NUTRIM), Maastricht University Medical Centre+, Maastricht, the Netherlands.

Background: Malnutrition is prevalent in hospitalized patients. To support muscle maintenance in older and chronically ill patients, a protein intake of 1.2-1. Read More

ESMO Open 2020 Jun;5(3)

Division of Cancer Sciences, The University of Manchester, Manchester, United Kingdom.

Background: Clinical guidelines recommend that parenteral nutrition (PN) is added to enteral nutrition (EN; supplemental parenteral nutrition (SPN)) in order to meet energy and protein needs in patients with cancer when EN alone is insufficient. However, although cancer-related malnutrition is common, there is poor awareness of the value of nutritional care, resulting in SPN being chronically underused.

Methods: We performed a targeted literature review and exploratory cost-utility analysis to gather evidence on the clinical effectiveness of SPN, and to estimate the potential cost-effectiveness of SPN versus EN alone in an example cancer setting. Read More

Nutrients 2020 Jun 20;12(6). Epub 2020 Jun 20.

Faculty of Health, Education and Life Sciences, Ravensbury House, Birmingham City University, City South Campus, Birmingham B15 3TN, UK.

Background: Although there are merits in using commercial "enteral nutrition formula" (ENF) compared with blended ENF, there is a growing preference for the use of blended ENF in many countries globally. However, the nutritional value and physical properties of blended ENF compared with commercial ENF may be limiting its use. We have not found any evidence of a meta-analysis on the nutritional value of blended diets in the adult population. Read More

Clin Nutr 2020 Jun 11. Epub 2020 Jun 11.

Medicine and Nutrition, The Larner College of Medicine, University of Vermont, Burlington, VT, USA. Electronic address:

Background: The Global Leadership Initiative on Malnutrition (GLIM) created a consensus-based framework consisting of phenotypic and etiologic criteria to record the occurrence of malnutrition in adults. This is a minimum set of practicable indicators for use in characterizing a patient/client as malnourished, considering the global variations in screening and nutrition assessment, and to be used across different health care settings. As with other consensus-based frameworks for diagnosing disease states, these operational criteria require validation and reliability testing as they are currently based solely on expert opinion. Read More

Indian J Tuberc 2020 Apr 4;67(2):152-158. Epub 2019 Apr 4.

Jan Swasthya Sahyog, India; St Louis University, St Louis, MO, USA.

Background: A secondary care hospital in rural India serving a highly tuberculosis (TB) and malnutrition endemic region.

Objective: In this study conducted on patients with chronic protein energy malnutrition (PEM) and TB, we sought to compare nurse-estimated vs. smartphone photograph analytic methods for assessing caloric intake and determine the incidence of refeeding hypophosphatemia (RH) and refeeding syndrome (RFS) in patients with TB. Read More

J Cachexia Sarcopenia Muscle 2020 Jun 16. Epub 2020 Jun 16.

Department of Health Sciences, Faculty of Science, Amsterdam Public Health research institute, Vrije Universiteit, Amsterdam, The Netherlands.

Background: Lower protein intake in older adults is associated with loss of muscle mass and strength. The present study aimed to provide a pooled estimate of the overall prevalence of protein intake below recommended (according to different cut-off values) among community-dwelling older adults, both within the general older population and within specific subgroups.

Methods: As part of the PRevention Of Malnutrition In Senior Subjects in the EU (PROMISS) project, a meta-analysis was performed using data from four cohorts (from the Netherlands, UK, Canada, and USA) and four national surveys [from the Netherlands, Finland (two), and Italy]. Read More

Nutrients 2020 Jun 14;12(6). Epub 2020 Jun 14.

Nephrology Consultant, Sardinian Regional Public Health Institution, 09047 Selargius, Italy.

This review aims to highlight the strengths and weaknesses emerging from diagnostic evaluations and prescriptions in an intent to prevent progression over time of malnutrition and/or protein-energy wasting (PEW) in hemodialysis (HD) patients. In particular, indications of the most effective pathway to follow in diagnosing a state of malnutrition are provided based on a range of appropriate chemical-clinical, anthropometric and instrumental analyses and monitoring of the nutritional status of HD patients. Finally, based on the findings of recent studies, therapeutic options to be adopted for the purpose of preventing or slowing down malnutrition have been reviewed, with particular focus on protein-calorie intake, the role of oral and/or intravenous supplements and efficacy of some classes of amino acids. Read More

Medicina (Kaunas) 2020 Jun 12;56(6). Epub 2020 Jun 12.

Department of Human Nutrition and Metabolomics, Pomeranian Medical University in Szczecin, 71-460 Szczecin, Poland.

The epidemic that broke out in Chinese Wuhan at the beginning of 2020 presented how important the rapid diagnosis of malnutrition (elevating during intensive care unit stay) and the immediate implementation of caloric and protein-balanced nutrition care are. According to specialists from the Chinese Medical Association for Parenteral and Enteral Nutrition (CSPEN), these activities are crucial for both the therapy success and reduction of mortality rates. The Chinese have published their recommendations including principles for the diagnosis of nutritional status along with the optimal method for nutrition supply including guidelines when to introduce education approach, oral nutritional supplement, tube feeding, and parenteral nutrition. Read More

Enferm Clin 2020 Jun;30 Suppl 4:227-230

Department of Nutrition, Gorontalo Health Polytechnic, Indonesia.

Objective: Stunting is one of moderate malnutrition caused by long-term lack of nutrition intake. Prevalence of stunting in Gorontalo (2018) was 32.5%. Read More

J Laparoendosc Adv Surg Tech A 2020 Jun 15. Epub 2020 Jun 15.

Gastrointestinal Surgical Center, Mansoura University, Mansoura, Egypt.

Increased popularity of one-anastomosis gastric bypass (OAGB) is associated with increased reports on the procedure-related complications. Protein-energy malnutrition (PEM) is a serious complication that may mandate reversal. The primary outcome of this study is the outcome of surgical management of PEM after OAGB. Read More

Aliment Pharmacol Ther 2020 Jul 14;52(2):311-318. Epub 2020 Jun 14.

Division of Gastroenterology, Massachusetts General Hospital, Boston, MA, USA.

Background: The prevalence of older adults with inflammatory bowel diseases (IBD) is increasing. Frailty is an important predictor of outcomes in many chronic disease states. The implications of frailty have not been well-delineated in IBD. Read More

JPEN J Parenter Enteral Nutr 2020 Jun 11. Epub 2020 Jun 11.

Clinical Nutrition and Metabolism, Department of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden.

Background: The Global Leadership Initiative on Malnutrition (GLIM) created a consensus-based framework consisting of phenotypic and etiologic criteria to record the occurrence of malnutrition in adults. This is a minimum set of practicable indicators for use in characterizing a patient/client as malnourished, considering the global variations in screening and nutrition assessment, and to be used across different healthcare settings. As with other consensus-based frameworks for diagnosing disease states, these operational criteria require validation and reliability testing, as they are currently based solely on expert opinion. Read More

Nutrients 2020 Jun 8;12(6). Epub 2020 Jun 8.

Department of Nephrology, Transplantology and Internal Medicine, Poznan University of Medical Sciences, 60-355 Poznan, Poland.

The positive impact of nutritional status on the health and treatment adequacy of peritoneal dialyzed patients has been well established. Protein intake is an important factor used to stratify malnutrition, with inadequate intake leading to protein-energy wasting during the course of therapy. In this review, we discuss the recommendations made by nephrological societies regarding nutrition in this population of dialysis patients. Read More

J Nephrol 2020 Jun 8. Epub 2020 Jun 8.

Department of Medical Epidemiology and Biostatistics (MEB), Karolinska Institutet, Nobels väg 12A, Box 281, 171 77, Stockholm, Sweden.

Background: In persons with CKD, adherence to plant-based diets is associated with lower risk of CKD progression and death, but underlying mechanisms are poorly characterized. We here explore associations between adherence to plant-based diets and measures of insulin sensitivity and inflammation in men with CKD stages 3-5.

Methods: Cross-sectional study including 418 men free from diabetes, aged 70-71 years and with cystatin-C estimated glomerular filtration rate (eGFR) <60 mL/min/1. Read More

Int J Food Sci 2020 14;2020:4803839. Epub 2020 May 14.

Department of Industrial Chemistry, Addis Ababa Science and Technology University, Addis Ababa, Ethiopia.

Consumption of nutritionally inadequate diets results in infant malnutrition. This study is aimed at formulating complementary foods from blend of orange-fleshed sweet potato, brown teff, and dark red kidney beans for infants aged 6-23 months. The Design-Expert 6. Read More

Can J Diet Pract Res 2020 06 4:1-7. Epub 2020 Jun 4.

Department of Kinesiology, University of Waterloo, Waterloo, ON.

To examine health characteristics of long-term care (LTC) residents prescribed therapeutic diets (promoting or restricting intake of key food components), to determine how these diets influenced intake and whether there were differences in food intake and malnutrition risk between residents with and without restrictive diets. Secondary analysis of the Making the Most of Mealtimes Study includes 435 residents with no/mild cognitive impairment in 32 LTC homes across 4 provinces. Health records were reviewed for diet prescriptions and other characteristics. Read More

PLoS One 2020 29;15(5):e0233615. Epub 2020 May 29.

Department of Public Health Sciences, The Pennsylvania State University College of Medicine, Hershey, PA, United States of America.

Background: Despite the high prevalence of childhood protein-energy malnutrition and vitamin A deficiency in sub-Saharan Africa, their association has not been explored in this region. A better understanding of the epidemiologic link could help define effective preventive strategies. We aimed to explore the association of vitamin A deficiency (VAD) with stunting, wasting, and underweight among preschool children in Uganda. Read More

Support Care Cancer 2020 May 20. Epub 2020 May 20.

Clinical Gerontology Department, CHU Bordeaux, 33000, Bordeaux, France.

Decreased health-related quality of life (HRQoL) is common in patients with cancer. We investigated the effects of dietary intervention and baseline nutritional status on worsening of HRQoL in older patients during chemotherapy. In this randomized control trial assessing the effect on mortality of dietary advice to increase dietary intake during chemotherapy, this post hoc analysis included 155 patients with cancer at risk of malnutrition. Read More

BMC Public Health 2020 May 20;20(1):736. Epub 2020 May 20.

Faculty of Nutrition, Federal University of Alagoas, Campus A.C. Simões, BR 104 Norte - Km 96.7 - Tabuleiro do Martins, CEP, Maceió, AL, 57072-970, Brazil.

Background: A study involving children from Alagoas (Northeast Brazil) revealed that, as a consequence of a drastic reduction in the prevalence of stunting between 1992 to 2005, (22.5 to 11.4%) combined with an increase in overweight prevalence (6. Read More

Cancer Chemother Pharmacol 2020 Jun 15;85(6):1049-1062. Epub 2020 May 15.

Department of Integrated Traditional Chinese and Western Medicine, Cancer Hospital of the University of Chinese Academy of Sciences/Zhejiang Cancer Hospital, Hangzhou, 310022, Zhejiang, China.

Background: Malnutrition is a common clinical symptom in cancer patients after chemotherapy, which is characterized by muscle wasting and metabolic dysregulation. The regulation of muscle metabolism by gut microbiota has been studied recently. However, there is no direct convincing evidence proving that manipulating gut microbiota homeostasis could regulate muscle metabolic disorder caused by chemotherapy. Read More

Nutrients 2020 May 12;12(5). Epub 2020 May 12.

Division of Nephrology, San Giovanni di Dio Hospital, 92100 Agrigento, Italy.

Protein Energy Wasting (PEW) in hemodialysis (HD) patients is a multifactorial condition due to specific pathology-related pathogenetic mechanisms, leading to loss of skeletal muscle mass in HD patients. Computed Tomography and Magnetic Resonance Imaging still represent the gold standard techniques for body composition assessment. However, their widespread application in clinical practice is difficult and body composition evaluation in HD patients is mainly based on conventional anthropometric nutritional indexes and bioelectrical impedance vector analysis (BIVA). Read More

Cochrane Database Syst Rev 2020 May 11;5:CD012616. Epub 2020 May 11.

Integrated Renal Service, Eastern Health, Box Hill, Australia.

Background: Malnutrition is common in patients with chronic kidney disease (CKD) on dialysis. Oral protein-based nutritional supplements are often provided to patients whose oral intake is otherwise insufficient to meet their energy and protein needs. Evidence for the effectiveness of oral protein-based nutritional supplements in this population is limited. Read More

Nutrients 2020 May 6;12(5). Epub 2020 May 6.

Division of Gastroenterology, Department of Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB T6G 2R3, Canada.

Malnutrition is associated with poor surgical outcomes, and therefore optimizing nutritional status preoperatively is very important. The purpose of this paper is to review the literature related to preoperative parenteral nutrition (PN) and to provide current evidence based guidance. A systemic online search of PubMed, Medline, and Cochrane Databases from January 1990 to February 2020 was done. Read More

J Hum Nutr Diet 2020 May 8. Epub 2020 May 8.

Division of Medical Sciences and Graduate Entry Medicine, School of Medicine, Centre for Kidney Research and Innovation, University of Nottingham, Royal Derby Hospital, Derby, UK.

Background: Skin autofluorescence (SAF), which is a measure of accumulation of advanced glycation end-products (AGE), and malnutrition are each associated with higher mortality in dialysis populations, although no studies have investigated these potentially related associations together. We simultaneously assessed SAF and malnutrition as risk factors for mortality in persons receiving dialysis.

Methods: SAF was measured in 120 haemodialysis and 31 peritoneal dialysis patients using an AGE Reader (DiagnOptics, Groningen, The Netherlands). Read More

Int Urol Nephrol 2020 Jun 4;52(6):1143-1153. Epub 2020 May 4.

Division of Nephrology, National Clinical Research Center for Aging and Medicine, Huashan Hospital, Shanghai Medical College, Fudan University, No. 12 Wulumuqi Road, Shanghai, 200040, China.

Purpose: Protein-energy wasting, characterized by decreased muscle mass, is one of the strongest predictors of mortality in patients on maintenance hemodialysis (MHD). As people get older, their muscle strength usually declines faster than muscle mass. However, the association between lower-limb muscle strength and all-cause mortality remains unclear. Read More

Clin Nutr 2020 Apr 18. Epub 2020 Apr 18.

Klinik für Allgemein-, Viszeral- und Onkologische Chirurgie, Klinikum St. Georg gGmbH, Delitzscher Straße 141, 04129, Leipzig, Germany.

Background & Aims: Malnutrition has been recognized as a major risk factor for adverse postoperative outcomes. The ESPEN Symposium on perioperative nutrition was held in Nottingham, UK, on 14-15 October 2018 and the aims of this document were to highlight the scientific basis for the nutritional and metabolic management of surgical patients.

Methods: This paper represents the opinion of experts in this multidisciplinary field and those of a patient and caregiver, based on current evidence. Read More

Clin Nutr ESPEN 2020 Jun 14;37:195-201. Epub 2020 Mar 14.

Department of Pediatric and Gastrointestinal and Surgery, Oslo University Hospital, Ullevål, Norway; Institute of Clinical Medicine, University of Oslo, Norway.

Background And Aims: Gastrointestinal (GI) symptoms, malabsorption, reduced food intake and weight loss are common sequela of gastrectomy. This can result in malnutrition with a subsequent prolonged recovery, reduced physical functioning and deteriorated quality of life (QoL). Few studies have investigated the relationship between GI-symptoms, QoL and malnutrition in long-term survivors of gastric cancer. Read More

Clin Nutr ESPEN 2020 Jun 2;37:121-128. Epub 2020 Apr 2.

Division of Surgery, Department of Clinical Science, Intervention and Technology (CLINTEC), Karolinska Institutet, Stockholm, Sweden; Department of Upper Abdominal Diseases, Karolinska University Hospital, Stockholm, Sweden.

Background: Assessment of malnutrition and its consequences are important aspects of curative management of patients with oesophageal cancer. The objective of the present study was to assess total energy expenditure using SenseWear Armband Mini® (SWA) as well as energy and protein intake in oesophageal cancer patients submitted to modern multimodality therapy.

Material And Methods: Twenty patients were recruited at the time of diagnosis of oesophageal cancer. Read More

Nutrients 2020 Apr 26;12(5). Epub 2020 Apr 26.

Department of Nutrition and Dietetics, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Seri Kembangan 43400, Selangor, Malaysia.

Background: The purpose of this study is to evaluate changes in nutrition impact symptoms (NIS) and nutritional and functional status that occur throughout radiotherapy in head and neck cancer (HNC) patients.

Methods: A prospective observational study of HNC inpatients who underwent radiotherapy with or without chemotherapy were recruited to participate. Fifty patients were followed for the periods before, in the middle and at the end of radiotherapy. Read More

Trials 2020 Apr 28;21(1):365. Epub 2020 Apr 28.

Dietetic and Nutritional Research Unit, Herlev-Gentofte University Hospital, Herlev, Denmark.

Background: During hospitalization, many older patients are at nutritional risk or malnourished, and their nutritional condition is often further impaired during hospitalization. After discharge, a "nutrition gap" often occurs in which the patient does not receive enough nutrition to ensure an optimal recovery.

Methods: The study is a randomized controlled study ongoing over 112 days. Read More

Food Sci Nutr 2020 Apr 20;8(4):2156-2164. Epub 2020 Mar 20.

Food and Nutritional Science Department of Food Technology and Process Engineering Wollega University Nekemte Ethiopia.

This study was aimed to evaluate nutritional and antinutritional contents of complementary foods from locally available and affordable raw materials (maize, pea, and anchote) grown in Western Ethiopia. The six formulated complementary diets analyzed for their proximate, mineral, and antinutritional continents were compared with Codex standards. The mineral ratios and molar ratios of the formulated diets were also evaluated and compared with each standard values. Read More

Eur Geriatr Med 2020 Feb 20;11(1):169-177. Epub 2019 Nov 20.

HAN University of Applied Sciences, Nijmegen, The Netherlands.

Purpose: The Joint Action Malnutrition in the Elderly (MaNuEL) Knowledge Hub was established to extend scientific knowledge, strengthen evidence-based practice, build a sustainable, transnational network of experts and harmonize research and clinical practice in the field of protein-energy malnutrition in older persons. This paper aims to summarize the main scientific results achieved during the 2-year project and to outline the recommendations derived.

Methods: 22 research groups from seven countries (Austria, France, Germany, Ireland, Spain, The Netherlands and New Zealand) worked together on 6 relevant domains of malnutrition-i. Read More

Eur Geriatr Med 2020 Apr 12;11(2):195-207. Epub 2020 Feb 12.

Center for Geriatric Medicine, Agaplesion Bethanien Hospital Heidelberg, Geriatric Center at the Heidelberg University, Rohrbacher Straße 149, 69126, Heidelberg, Germany.

Purpose: Since there is only limited evidence available for geriatric rehabilitation patients, this systematic review and meta-analysis aims to characterize the nutritional status in this population and its relationship with functionality.

Methods: Eight databases were searched for full-text articles reporting baseline nutritional intake and status of adults ≥ 60 years in rehabilitation settings. Pooled estimates were calculated for prevalence of malnutrition and risk of malnutrition based on the Mini Nutritional Assessment (MNA) and for mean body mass index (BMI). Read More

Front Med (Lausanne) 2020 27;7:99. Epub 2020 Mar 27.

School of Biomedical Engineering, Taipei Medical University, Taipei, Taiwan.

Cardiac sympathetic response (CSR) and malnutrition-inflammation syndrome (MIS) score are validated assessment tools for patients' health condition. We aim to evaluate the joint effect of CSR and MIS on all-cause and cardiovascular (CV) mortality in patients with hemodialysis (HD). Changes in normalized low frequency (ΔnLF) during HD were utilized for quantification of CSR. Read More

J Am Coll Nutr 2020 Apr 10:1-7. Epub 2020 Apr 10.

Internal Medicine Department, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brasil.

The aim of this study was to characterize nutritional status, body composition, oxidative stress, and inflammatory activity and to determine the possible associations between nutritional status and clinical variables in advanced cancer patients. This was a cross-sectional study of 46 elderly cancer patients under palliative care with a prognosis of 30 days or more. Nutritional status, food intake, anthropometry, body composition (deuterium oxide method), metabolic profile, inflammation damage (C-reactive protein), oxidative damage (8-hydroxy-2'-deoxyguanosine), and symptom intensity were evaluated. Read More

Appl Physiol Nutr Metab 2020 Apr 9. Epub 2020 Apr 9.

University of Saskatchewan College of Pharmacy and Nutrition, 70398, Saskatoon, Saskatchewan, Canada ;

Protein-energy malnutrition (PEM) commonly arises after stroke. We investigated the effects of preventing PEM on spontaneous recovery of forelimb use, infarct size, and the acute phase response (APR) in the chronic post-stroke period. Male, adult Sprague-Dawley rats were acclimatized to control diet (12. Read More

Transl Gastroenterol Hepatol 2020 5;5:22. Epub 2020 Apr 5.

Department of Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.

Malnutrition is a critical problem in patients with gastric cancer (GC); however, no universally accepted marker that is convenient for clinical use has been defined. Recently, body composition has attracted considerable attention as a means to assess nutrition status in patients with cancer. The clinical role of skeletal muscle mass has also been increasingly recognized. Read More

Nutrition 2020 Jul - Aug;75-76:110747. Epub 2020 Feb 11.

Center for Nutrition and Bowel Disease, Aalborg University Hospital, Aalborg, Denmark; Clinical Institute, Aalborg University, Aalborg, Denmark. Electronic address:

Objective: Disease-related malnutrition (DRM) in hospitalized patients is known to have significant negative impact on clinical outcomes. Meanwhile, DRM in gastroenterology outpatients is scarcely investigated. The aim of this study was to investigate the prevalence of unintentional weight loss (UWL) and reduced food intake (RFI) as contributors to the risk of DRM in outpatients. Read More

Clin Nutr ESPEN 2020 Apr 4;36:134-138. Epub 2020 Feb 4.

Department of Therapeutic Nutrition, Institute of Biomedical Sciences, Tokushima University Graduate School, Japan; Department of Nutrition, Tokushima University Hospital, Japan. Electronic address:

Background & Aims: In dialysis patients, malnutrition is a poor prognostic factor. In patients with chronic kidney disease (CKD), malnutrition is qualitatively different from general malnutrition, which is defined as "Protein-Energy Wasting (PEW)." Dietary therapy for the enhancement of PEW requires the aggressive intake of protein. Read More

Clin Nutr ESPEN 2020 Apr 6;36:116-127. Epub 2020 Feb 6.

School of Public Health, Physiotherapy and Sports Science, University College Dublin, Dublin, Ireland; UCD Institute of Food and Health, University College Dublin, Dublin, Ireland.

Background & Aims: Malnutrition or undernutrition, arising from a deficiency of energy and protein intake, occurs commonly among community-dwelling individuals in developed countries. Once identified, malnutrition can be effectively treated in the majority of cases with dietary advice and the prescription of oral nutritional supplements (ONS) for patients who can eat and drink orally. However, previous research has reported inadequate screening and treatment of malnutrition in the community. Read More

Pediatric Health Med Ther 2020 10;11:95-100. Epub 2020 Mar 10.

Department of Pediatrics, MIMER Medical College, Talegaon Dabhade 410507, India.

Objective: To compare age and protein-energy malnutrition (PEM) - the predispositions - and fever and abnormal leukocyte count (ALC) - the SIRS criteria - in hospitalized children with and without diarrhea.

Design: A prospective case-control study.

Setting: A pediatric ward of a general hospital in a low-resource setting. Read More

Int J Nephrol 2020 5;2020:9528014. Epub 2020 Mar 5.

Service de Cardiologie, Centre Hospitalier Universitaire, Guadeloupe, France.

Natriuretic peptides, brain natriuretic peptide (BNP), and N-terminal probrain natriuretic peptide (NT-proBNP) are mainly known as diagnostic markers for heart failure with high diagnostic and prognostic values in the general population. In patients who are undergoing hemodialysis (HD), changes in NT-proBNP can be related to noncardiac problems such as fluid overload, inflammation, or malnutrition and can also be influenced by the dialysis characteristics. The current review aimed to summarize findings from studies on the association between NT-proBNP and malnutrition in HD patients. Read More

Biotechnol Adv 2020 Jul - Aug;41:107536. Epub 2020 Mar 16.

The California Center for Algae Biotechnology, University of California, San Diego, La Jolla, CA, USA; Division of Biological Sciences, University of California, San Diego, La Jolla, CA, USA. Electronic address:

One of the key challenges that we face in the 21st century is the need to feed an ever-increasing human population with increasingly limited natural resources. Even today it is estimated that roughly 1 out of 9 people in the world are undernourished, of which the most important factor is protein-energy malnutrition. By establishing microalgae as a new food and feed platform, we have the opportunity to increase the supply of these essential products to address global demands in a more efficient and environmentally sustainable way. Read More

JPEN J Parenter Enteral Nutr 2020 Mar 19. Epub 2020 Mar 19.

Department of Gastroenterology and Hepatology-Dietetics, Radboudumc, Nijmegen, the Netherlands.

Background: Whether decreased physical functioning of patients with mitochondrial disease (MD) is related to altered body composition or low protein intake needs clarification at the background of the nutrition state.

Methods: In this 2-site cross-sectional study, MD patients were age-, body mass index (BMI)-, and gender-matched to controls. Body composition was assessed by dual-energy x-ray absorptiometry. Read More