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    9299 results match your criteria Protein-Energy Malnutrition

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    The UN Decade of Nutrition, the NOVA food classification and the trouble with ultra-processing.
    Public Health Nutr 2017 Mar 21:1-13. Epub 2017 Mar 21.
    1Department of Nutrition,School of Public Health,University of São Paulo,Av. Dr Arnaldo 715,São Paulo 01246-904,Brazil.
    Given evident multiple threats to food systems and supplies, food security, human health and welfare, the living and physical world and the biosphere, the years 2016-2025 are now designated by the UN as the Decade of Nutrition, in support of the UN Sustainable Development Goals. For these initiatives to succeed, it is necessary to know which foods contribute to health and well-being, and which are unhealthy. The present commentary outlines the NOVA system of food classification based on the nature, extent and purpose of food processing. Read More

    Impact of Nutritional Intervention on Length of Hospital Stay and Mortality among Hospitalized Patients with Malnutrition: A Clinical Randomized Controlled Trial.
    J Am Coll Nutr 2017 Mar 20:1-5. Epub 2017 Mar 20.
    b Biomedical Research Unit of the Mexican Social Security Institute at Durango , Durango , Dgo. , México.
    Objective: The objective of this study was to evaluate the impact of a nutritional intervention on hospital stay and mortality among hospitalized patients with malnutrition.

    Methods: Hospitalized patients with a diagnosis of malnutrition were enrolled and randomly allocated to either an intervention or control group. Participants in the intervention group received an individualized nutrition plan according to energy and protein (1. Read More

    Intrauterine growth restriction programs the hypothalamus of adult male rats: integrated analysis of proteomic and metabolomic data.
    J Proteome Res 2017 Mar 17. Epub 2017 Mar 17.
    Programming of hypothalamic functions regulating energy homeostasis may play a role in intrauterine growth restriction (IUGR)-induced adulthood obesity. The present study investigated the effects of IUGR on the hypothalamus proteome and metabolome of adult rats submitted to 50% protein-energy restriction throughout pregnancy. Proteomic and metabolomic analyzes were performed by data independent acquisition mass spectrometry and multiple reaction monitoring, respectively. Read More

    Relationship between pickiness and subsequent development in body mass index and diet intake in obesity prone normal weight preschool children.
    PLoS One 2017 15;12(3):e0172772. Epub 2017 Mar 15.
    Research Unit for Dietary Studies at The Parker Institute, Bispebjerg and Frederiksberg University Hospital, The Capital Region, Frederiksberg, Denmark.
    Background: Most children have periods in their life where they reject familiar as well as non-familiar food items and this is often referred to as pickiness. The consequences of pickiness may be malnutrition and, if prolonged, potentially lower body weight. However, studies investigating the consequence of pickiness on subsequent changes in diet intake and weight are limited. Read More

    Role of domiciliary and family carers in individualised nutrition support for older adults living in the community.
    Maturitas 2017 Apr 12;98:20-29. Epub 2017 Jan 12.
    Faculty of Health Sciences and Medicine, Bond University, Robina, Queensland, 4226, Australia; Department of Nutrition and Dietetics, Princess Alexandra Hospital, Woolloongabba, Queensland 4102, Australia.
    Protein-energy malnutrition is common amongst people aged 65 years and older, has a multifactorial aetiology, and numerous negative outcomes. Domiciliary carers (non-clinical paid carers) and family carers (including family, friends and neighbours) are required to support the increasing demand for in-home assistance with activities of daily living due to the ageing population. This review provides insight into the role of both domiciliary and family carers in providing individualised nutrition support for older, community-dwelling adults with malnutrition. Read More

    Protein Nutrition and Malnutrition in CKD and ESRD.
    Nutrients 2017 Feb 27;9(3). Epub 2017 Feb 27.
    Division of Nephrology and Hypertension, Department of Medicine, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA.
    Elevated protein catabolism and protein malnutrition are common in patients with chronic kidney disease (CKD) and end-stage renal disease (ESRD). The underlying etiology includes, but is not limited to, metabolic acidosis intestinal dysbiosis; systemic inflammation with activation of complements, endothelin-1 and renin-angiotensin-aldosterone (RAAS) axis; anabolic hormone resistance; energy expenditure elevation; and uremic toxin accumulation. All of these derangements can further worsen kidney function, leading to poor patient outcomes. Read More

    Health insurance or subsidy has universal advantage for management of hospital malnutrition unrelated to GDP.
    Asia Pac J Clin Nutr 2017 Mar;26(2):247-254
    Jagiellonian University Medical College, Chair of Epidemiology and Preventive Medicine, Department of Epidemiology, Krakow, Poland.
    Background And Objectives: Protein-energy and micronutrient malnutrition are global public health problems which, when not prevented and severe, require medical management by clinicians with nutrition expertise, preferably as a collectively skilled team, especially when disease-related. This study aimed to investigate barriers and facilitators of clinical nutrition services (CNS), especially the use of oral, enteral (EN) and parenteral (PN) nutrition in institutional and home settings.

    Methods And Study Design: An international survey was performed between January and December 2014 in twenty-six countries from all continents. Read More

    Serum zinc evolution in dysphagic patients that underwent endoscopic gastrostomy for long term enteral feeding.
    Asia Pac J Clin Nutr 2017 Mar;26(2):227-233
    Centro de Estudos de Doenças Crónicas, CEDOC, NOVA Medical School / Faculdade de Ciências Médicas, Universidade Nova de Lisboa, Lisbon, Portugal.
    Background And Objectives: Patients undergoing endoscopic gastrostomy (PEG) present with protein-energy malnutrition (PEM) but little is known about zinc status. Our aim was to evaluate serum zinc, its relationship with serum proteins and with the nature of the underlying disorder, during the first 3 months of PEG feeding.

    Methods And Study Design: Prospective observational study during a 3-month period after gastrostomy. Read More

    The Impact of Trained Volunteer Mealtime Assistants on the Dietary Intake of Older Female In-Patients: The Southampton Mealtime Assistance Study.
    J Nutr Health Aging 2017 ;21(3):320-328
    Dr Helen Roberts, Academic Geriatric Medicine Mailpoint 807, Southampton General Hospital, Southampton SO16 6YD, Tel: 023 8120 4354 Email :
    Objective: Malnutrition among older hospital inpatients is common and is associated with poor clinical outcomes. Time-pressured staff may struggle to provide mealtime assistance. This study aimed to evaluate the impact of trained volunteer mealtime assistants on the dietary intake of older inpatients. Read More

    Rehabilitation and nutritional support for sarcopenic dysphagia and tongue atrophy after glossectomy: A case report.
    Nutrition 2017 Mar 22;35:128-131. Epub 2016 Nov 22.
    Department of Otolaryngology, Head and Neck Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka City, Japan.
    Swallowing dysfunction is related to long-term weight loss and reduced body mass index in patients with head and neck cancer. We describe a 76-y-old woman who had severe sarcopenic dysphagia and atrophy of the reconstructed tongue for 17 mo after subtotal glossectomy due to tongue cancer and lost 14 kg during that period. Upon admission, the patient received diagnoses of malnutrition in the context of social or environmental circumstances with insufficient energy intake, loss of muscle mass, localized fluid accumulation, weight loss, and sarcopenia due to reduced skeletal muscle mass (skeletal muscle index <3. Read More

    Performance of subjective global assessment and malnutrition inflammation score for monitoring the nutritional status of older adults on hemodialysis.
    Clin Nutr 2017 Feb 3. Epub 2017 Feb 3.
    Nutrition Institute, Rio de Janeiro State University, Rio de Janeiro, Brazil. Electronic address:
    Background & Aims: Studies assessing the performance of 7-point subjective global assessment (7p-SGA) and malnutrition inflammation score (MIS) to assess longitudinal changes in nutritional status are lacking. Thus, we aimed to investigate whether longitudinal changes in 7p-SGA and MIS were associated with changes in objective parameters of nutritional status, as well as to evaluate the prognostic value of 7p-SGA and MIS on hospitalization events.

    Methods: One hundred and four patients aged ≥60 years (70. Read More

    Evidence-based interventions for improvement of maternal and child nutrition in low-income settings: what's new?
    Curr Opin Clin Nutr Metab Care 2017 Feb 15. Epub 2017 Feb 15.
    aCentre for Global Child Health, The Hospital for Sick Children, Toronto, Ontario, CanadabCentre of Excellence in Women and Child Health, Aga Khan University, Karachi, Pakistan.
    Purpose Of Review: Maternal and child malnutrition continues to disproportionately affect low and middle-income countries, contributing to high rates of morbidity, mortality, and suboptimal development. This article reviews evidence from recent systematic reviews and studies on the effectiveness of interventions to improve nutritional status in these especially vulnerable populations.

    Recent Findings: Macronutrients provided to expectant mothers in the form of balanced protein energy supplements can improve fetal growth and birth outcomes, and new research suggests that lipid nutrient supplements can reduce both stunting and wasting in newborns. Read More

    Parallel changes in cortical neuron biochemistry and motor function in protein-energy malnourished adult rats.
    Neuroimage 2017 Feb 4;149:275-284. Epub 2017 Feb 4.
    Neuroscience Research Group, Department of Anatomy and Cell Biology and College of Pharmacy and Nutrition University of Saskatchewan, D Wing GD30 (Box 1) Health Sciences, 107 Wiggins Road, Saskatoon, SK, Canada, S7N 5E5; College of Pharmacy and Nutrition, Canada; Cameco MS Neuroscience Center, University of Saskatchewan, Saskatoon, Canada. Electronic address:
    While protein-energy malnutrition in the adult has been reported to induce motor abnormalities and exaggerate motor deficits caused by stroke, it is not known if alterations in mature cortical neurons contribute to the functional deficits. Therefore, we explored if PEM in adult rats provoked changes in the biochemical profile of neurons in the forelimb and hindlimb regions of the motor cortex. Fourier transform infrared spectroscopic imaging using a synchrotron generated light source revealed for the first time altered lipid composition in neurons and subcellular domains (cytosol and nuclei) in a cortical layer and region-specific manner. Read More

    Relationship between epigenetic regulation, dietary habits, and the Developmental Origins of Health and Disease theory.
    Congenit Anom (Kyoto) 2017 Feb 7. Epub 2017 Feb 7.
    Laboratory of Nutritional Physiology, Graduate School of Nutritional and Environmental Sciences, University of Shizuoka, Shizuoka, Japan.
    Environmental stressors during developmental stages are hypothesized to increase the risk of developing metabolic diseases such as obesity, type 2 diabetes, hypertension, and psychiatric diseases during later life. This theory is known as the Developmental Origins of Health and Disease (DOHaD). Recent studies suggest that accumulation of environmental stress, including during developmental stages, is internalized as acquired information designated as "epigenetic memory. Read More

    Biofortification in Millets: A Sustainable Approach for Nutritional Security.
    Front Plant Sci 2017 23;8:29. Epub 2017 Jan 23.
    T. A. Lourdusamy Unit for Plant Tissue Culture and Molecular Biology, Department of Plant Biology and Biotechnology, Loyola College Chennai, India.
    Nutritional insecurity is a major threat to the world's population that is highly dependent on cereals-based diet, deficient in micronutrients. Next to cereals, millets are the primary sources of energy in the semi-arid tropics and drought-prone regions of Asia and Africa. Millets are nutritionally superior as their grains contain high amount of proteins, essential amino acids, minerals, and vitamins. Read More

    The efficacy of Protected Mealtimes in hospitalised patients: a stepped wedge cluster randomised controlled trial.
    BMC Med 2017 Feb 7;15(1):25. Epub 2017 Feb 7.
    Department of Nutrition, Dietetics and Food, Monash University, 264 Ferntree Gully Road, Notting Hill, Victoria, 3168, Australia.
    Background: Protected Mealtimes is an intervention developed to address the problem of malnutrition in hospitalised patients through increasing positive interruptions (such as feeding assistance) whilst minimising unnecessary interruptions (including ward rounds and diagnostic procedures) during mealtimes. This clinical trial aimed to measure the effect of implementing Protected Mealtimes on the energy and protein intake of patients admitted to the subacute setting.

    Methods: A prospective, stepped wedge cluster randomised controlled trial was undertaken across three hospital sites at one health network in Melbourne, Australia. Read More

    Nutrition, frailty, and sarcopenia.
    Aging Clin Exp Res 2017 Feb 2;29(1):43-48. Epub 2017 Feb 2.
    Institute for Biomedicine of Aging, University of Erlangen-Nürnberg, Nuremberg, Germany.
    Frailty and sarcopenia are important concepts in the quest to prevent physical dependence, as geriatrics are shifting towards identifications of early stages of disability. Definitions of both sarcopenia and frailty are still developing, and both concepts clearly overlap in their physical aspects. Malnutrition (both undernutrition and obesity) plays a key role in the pathogenesis of frailty and sarcopenia. Read More

    From Evidence to Clinical Practice.
    Nutr Clin Pract 2017 Jan 1:884533616688432. Epub 2017 Jan 1.
    4 Abdominal Centre, Rigshospital, Copenhagen University Hospital, Copenhagen, Denmark.
    Background: The aim of this study was to investigate if a protein-enriched menu in conjunction with individualized dietary counseling would increase energy and protein intake in hospitalized patients at nutrition risk compared with providing the protein-enriched menu as a stand-alone intervention.

    Method: Data from medical and surgical hospitalized patients were prospectively collected and compared with a historical intervention group (HIG). Primary outcome was the number of patients achieving >75% of energy and protein requirements. Read More

    Resting energy expenditure in the risk assessment of anticancer treatments.
    Clin Nutr 2017 Jan 19. Epub 2017 Jan 19.
    Medical Oncology Department, Cancer Research for Personalized Medicine (CARPEM), Paris Centre Teaching Hospitals, Paris Descartes University, USPC, Paris, France.
    Background & Aims: Alterations of nutritional and performance status (PS) are associated with higher risk of chemotherapy toxicity. Increased resting energy expenditure (REE) is frequent in cancer patients and may contribute to cachexia. We investigated whether abnormal energetic metabolism could predict early acute limiting toxicities (ELT) of anticancer treatments. Read More

    ESPEN guideline: Clinical nutrition in inflammatory bowel disease.
    Clin Nutr 2017 Apr 31;36(2):321-347. Epub 2016 Dec 31.
    Institut für Ernährungsmedizin (180) Universität Hohenheim, Fruwirthstr. 12, 70593 Stuttgart, Germany. Electronic address:
    Introduction: The ESPEN guideline presents a multidisciplinary focus on clinical nutrition in inflammatory bowel disease (IBD).

    Methodology: The guideline is based on extensive systematic review of the literature, but relies on expert opinion when objective data were lacking or inconclusive. The conclusions and 64 recommendations have been subject to full peer review and a Delphi process in which uniformly positive responses (agree or strongly agree) were required. Read More

    The Effects of Compliance with Nutritional Counselling on Body Composition Parameters in Head and Neck Cancer Patients under Radiotherapy.
    J Nutr Metab 2017 1;2017:8631945. Epub 2017 Jan 1.
    Department of Anesthesiology and Intensive Care, Ege University School of Medicine, Bornova, 35100 Izmir, Turkey.
    Background. Radiotherapy (RT) has been associated with increased risk of malnutrition in cancer patients, particularly in those with head and neck cancer (HNC). The aim of this prospective study was to evaluate the effects of compliance of patients with individual dietary counselling on body composition parameters in HNC patients under RT. Read More

    Prognostic significance of nonprotein respiratory quotient in patients with liver cirrhosis.
    Medicine (Baltimore) 2017 Jan;96(3):e5800
    Division of Hepatobiliary and Pancreatic Disease, Department of Internal Medicine, Hyogo College of Medicine, Hyogo, Japan.
    The aim of this study was to examine the effect of nonprotein respiratory quotient (npRQ), as assessed using indirect calorimetry, on clinical outcomes in patients with liver cirrhosis (LC). A total of 244 LC patients were evaluated in this study. For the univariate analysis, for each continuous variable, the optimal cutoff value that maximized the sum of sensitivity and specificity was selected using receiver operating curve (ROC) analysis for survival. Read More

    Low-dose dialysis combined with low protein intake can maintain nitrogen balance in peritoneal dialysis patients in poor economies
    Clin Nephrol 2017 Feb;87 (2017)(2):84-92
    Objective: Due to limited economic conditions, we tried to provide "fitted" dialysis doses instead of the doses recommended by the international guidelines to the individual patients. In the present cross-sectional study, we studied the dialysis adequacy and nutritional status of 5 peritoneal dialysis patients who had a low dialysis dose (2 bags, 4,000 mL/day).

    Methods: The 3-day dietary records were reviewed to calculate patients' energy, protein, and nitrogen intake (NI). Read More

    Previous Repeated Exposure to Food Limitation Enables Rats to Spare Lipid Stores during Prolonged Starvation.
    Physiol Biochem Zool 2017 Jan/Feb;90(1):63-74. Epub 2016 Nov 7.
    The risk of food limitation and, ultimately, starvation dates back to the dawn of heterotrophy in animals, yet starvation remains a major factor in the regulation of modern animal populations. Researchers studying starvation more than a century ago suggested that animals subjected to sublethal periods of food limitation are somehow more tolerant of subsequent starvation events. This possibility has received little attention over the past decades, yet it is highly relevant to modern science for two reasons. Read More

    Maternal undernutrition programs the apelinergic system of adipose tissue in adult male rat offspring.
    J Dev Orig Health Dis 2017 Feb;8(1):3-7
    1EA4489,Équipe Malnutrition Maternelle et Programmation des Maladies Métaboliques,Univ. Lille,Lille,France.
    Based on the Developmental Origin of Health and Disease concept, maternal undernutrition has been shown to sensitize adult offspring to metabolic pathologies such as obesity. Using a model of maternal 70% food restriction in pregnant female rats throughout gestation (called FR30), we previously reported that obesity-prone adult male rat offspring displayed hyperleptinemia with modifications in leptin and leptin receptor messenger RNA (mRNA) levels in white adipose tissue (WAT). Apelin is a member of the adipokine family that regulates various aspects of energy metabolism and WAT functionality. Read More

    A rapid assessment and response approach for socially marketed nutrition commodities in Viet Nam.
    Asia Pac J Clin Nutr 2017 Jan;26(1):182-189
    National Institute for Nutrition (NIN), Ha Noi, Vietnam.
    Background: The leading cause of death in children in developing countries is protein-energy malnutrition. In Viet Nam, 25.9% of children under 5 experience stunted growth and 6. Read More

    Nutrition assessment and its relationship with performance and Glasgow prognostic scores in Vietnamese patients with esophageal cancer.
    Asia Pac J Clin Nutr 2017 Jan;26(1):49-58
    National Cancer Hospital, Hanoi, Vietnam.
    Background And Objectives: To determine the nutritional status of patients with esophageal cancer, and to investigate its relationship with performance status and prognosis.

    Methods And Study Design: This clinical, cross-sectional study was conducted from August 2014 to February 2015 at National Cancer Hospital, Hanoi, Vietnam. Stage III/IV esophageal cancer patients were assessed for their nutritional status (patient-generated subjective global assessment (PG-SGA) and SGA scores, BMI, mid-arm circumference (MAC), energy and protein intakes, weight changes, Karnofsky and Eastern cooperative oncology group performance scores (KPS/ECOG), and Glasgow prognostic score (GPS). Read More

    Relationship of aging and nutritional status to innate immunity in tube-fed bedridden patients.
    Asia Pac J Clin Nutr 2017 Jan;26(1):36-41
    Department of Internal Medicine, Division of Gastroenterology, Showa University School of Medicine, Shinagawa-ku, Tokyo, Japan.
    Background And Objectives: Aging and malnutrition are known to influence immune functions. The aim of this study was to investigate the relationship of aging and malnutrition to innate immune functions in tube-fed bedridden patients.

    Methods And Study Design: A cross-sectional survey was performed in 71 tube-fed bedridden patients aged 50-95 years (mean age±SD, 80. Read More

    Nutrient composition of premixed and packaged complementary foods for sale in low- and middle-income countries: Lack of standards threatens infant growth.
    Matern Child Nutr 2016 Dec 22. Epub 2016 Dec 22.
    Friedman School of Nutrition Science and Policy, Tufts University, Boston, Massachusetts, USA.
    Premixed flours for infant porridge are increasingly produced and sold in developing countries to complement continued breastfeeding. Such complementary food (CF) products have known efficacy against malnutrition in children from 6 to 24 months of age, but ingredient ratios and production processes may vary. This study provides the first systematic measurement of their actual nutrient composition. Read More

    Keto-analogues and essential aminoacids and other supplements in the conservative management of chronic kidney disease.
    Panminerva Med 2017 Jun 21;59(2):149-156. Epub 2016 Dec 21.
    Territorial Department of Nephrology and Dialysis, ASL 8, Cagliari, Italy.
    The manipulation of dietary protein intake is the mainstay of nutritional treatment of patients affected by chronic renal insufficiency, with the aim to reduce the burden of uremic toxins in order to decrease uremic toxicity and delay the need for dialysis. Consensus exists regarding the benefit of progressive protein restriction towards delaying the progression of renal failure and the need for dialysis, provided adequate energy supply. Although pivotal, protein restriction is only one aspect of the dietary management of chronic kidney disease (CKD) patients. Read More

    A short nutritional intervention in a cohort of hematological inpatients improves energy and protein intake and stabilizes nutritional status.
    Nutr Hosp 2016 Nov 29;33(6):1347-1353. Epub 2016 Nov 29.
    Clinical Nutrition and Dietetics Unit. Department of Endocrinology and Nutrition, Complejo Asistencial Universitario de León. León.
    Introduction: Oncohematological diseases are associated with an important prevalence of malnutrition.

    Aim: Our aim is to determine if early recognition and treatment of malnourished hematological inpatients can improve their oral intake, nutritional status and reduce the length of hospital stay.

    Methods: Prospective 2-year study conducted in a cohort of hematology inpatients. Read More

    Dilated Cardiomyopathy Induced by Chronic Starvation and Selenium Deficiency.
    Case Rep Pediatr 2016 22;2016:8305895. Epub 2016 Nov 22.
    Department of Pediatric Cardiology, University of Texas Medical Branch, Galveston, TX 77555, USA.
    Protein energy malnutrition (PEM) has been rarely documented as a cause of cardiovascular abnormalities, including dilated cardiomyopathy. Selenium is responsible for antioxidant defense mechanisms in cardiomyocytes, and its deficiency in the setting of PEM and disease related malnutrition (DRM) may lead to exacerbation of the dilated cardiomyopathy. We report a rare case of a fourteen-year-old boy who presented with symptoms of congestive heart failure due to DRM and PEM (secondary to chronic starvation) along with severe selenium deficiency. Read More

    Communication: Homocysteine, Thioretinaco Ozonide, Oxidative Phosphorylation, Biosynthesis of Phosphoadenosine Phosphosulfate and the Pathogenesis of Atherosclerosis.
    Ann Clin Lab Sci 2016 Dec;46(6):701-704
    Pathology and Laboratory Medicine Service, Boston Veterans Affairs Healthcare System, and Department of Pathology, Harvard Medical School, Boston, MA, USA
    The formation of phosphoadenosine phosphosulfate (PAPS) is accomplished by the action of the enzyme 3'-phosphoadenosine 5'-phosphosulfate synthase (PAPSS) in two sequential reactions, consisting of (1) reaction of inorganic sulfate with adenosine triphosphate (ATP) to form adenosine phosphosulfate (APS) and pyrophosphate and (2) reaction of APS with inorganic phosphate to form PAPS and adenosine diphosphate (ADP). The hydrolysis of guanosine triphosphate (GTP) is coordinated with synthesis of APS in a reaction sequence which provides the chemical energy for synthesis of APS. The present proposal is that the active site of oxidative phosphorylation, thioretinaco ozonide oxygen (TR2CoO3O2), functions as the source of APS synthesis from nicotinamide adenine dinucleotide (NAD(+)) and hydrosulfate (HSO4(-)) by reduction of the complex with electrons from electron transport complexes, releasing APS and thioretinaco hydroperoxide (TR2CoO3O2H) upon protonation. Read More

    A foodservice approach to enhance energy intake of elderly subacute patients: a pilot study to assess impact on patient outcomes and cost.
    Age Ageing 2016 Dec 14. Epub 2016 Dec 14.
    Department of Nutrition and Dietetics, Monash University, Level 1, 264 Ferntree Gully Road , Notting Hill, Victoria 3168, Australia.
    Background: effective strategies are required to support the nutritional status of patients.

    Objectives: to evaluate a foodservice nutrition intervention on a range of participant outcomes and estimate its cost.

    Design: parallel controlled pilot study. Read More

    Nutrient deficiencies prior to bariatric surgery.
    Curr Opin Clin Nutr Metab Care 2017 Mar;20(2):138-144
    aDivisions of Endocrinology bGastroenterology and Hepatology, Mayo Clinic, Scottsdale, Arizona, USA.
    Purpose Of Review: The purpose of this review is to provide an update of recent additions to our understanding of the prevalence of nutrient deficiencies and the potential role of preoperative weight loss in contributing to these deficiencies in obese individuals planning to undergo bariatric surgery.

    Recent Findings: Recent reports that have included bariatric surgery candidates from sites around the world have shown consistent deficiencies in a variety of nutrients. Although protein-energy malnutrition is uncommon preoperatively, micronutrient deficiencies occur commonly with multiple deficiencies often present in the same individual. Read More

    Older patients' use of technology for a post-discharge nutritional intervention - A mixed-methods feasibility study.
    Int J Med Inform 2017 Jan 6;97:312-321. Epub 2016 Nov 6.
    Copenhagen University Hospital, Department of Internal Medicine, Herlev Ringvej 75, DK-2730 Herlev, Denmark. Electronic address:
    Background: Malnutrition is frequent in older people and a precursor for morbidity and hospitalisation; furthermore low intake and weight loss during and after hospitalisation is well-described. Such patients are often excluded from technology projects on account of lack of skills. This is a barrier for their access to many current and future health care offers. Read More

    Nutritional supplementation for hip fracture aftercare in older people.
    Cochrane Database Syst Rev 2016 Nov 30;11:CD001880. Epub 2016 Nov 30.
    Health Services Research Unit, School of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Health Sciences Building, Foresterhill, Aberdeen, UK, AB25 2ZD.
    Background: Older people with hip fractures are often malnourished at the time of fracture, and subsequently have poor food intake. This is an update of a Cochrane review first published in 2000, and previously updated in 2010.

    Objectives: To review the effects (benefits and harms) of nutritional interventions in older people recovering from hip fracture. Read More

    The Effect of BCAA and ISO-WHEY Oral Nutritional Supplements on Dialysis Adequacy.
    Nephrourol Mon 2016 Nov 5;8(6):e34993. Epub 2016 Sep 5.
    Faculty of Physical Education and Sport Sciences, Shahid Rajaee Teacher Training University, Tehran, IR Iran.
    Background: Protein-energy malnutrition is a common problem in hemodialysis patients and has different outcomes such as reduced quality of life, longer hospitalization time, lower dialysis adequacy, and higher mortality rate. Investigation of dialysis adequacy is an important method for assessing hemodialysis patients, and improving the dialysis adequacy is an important healthcare team goal.

    Objectives: The present study aims to investigate and compare the effects of BCAA and ISO-WHEY oral nutritional supplements on dialysis adequacy. Read More

    Trends, causes, and risk factors of mortality among children under 5 in Ethiopia, 1990-2013: findings from the Global Burden of Disease Study 2013.
    Popul Health Metr 2016 14;14:42. Epub 2016 Nov 14.
    Institute for Health Metrics and Evaluation, University of Washington, Seattle, USA.
    Background: Ethiopia has made remarkable progress in reducing child mortality over the last two decades. However, the under-5 mortality rate in Ethiopia is still higher than the under-5 mortality rates of several low- and middle-income countries (LMIC). On the other hand, the patterns and causes of child mortality have not been well investigated in Ethiopia. Read More

    N-Terminal Pro-B-Type Natriuretic Peptide as a Biomarker for Loss of Muscle Mass in Prevalent Hemodialysis Patients.
    PLoS One 2016 21;11(11):e0166804. Epub 2016 Nov 21.
    Division of Nephrology, Department of Medicine, Showa University School of Medicine, Tokyo, Japan.
    Protein-energy wasting (PEW) is common in hemodialysis (HD) patients. A recent study demonstrated that a high level of N-terminal pro-B-type natriuretic peptide (NT-proBNP) may be associated with PEW in those patients. This prospective study aimed to assess the association of NT-proBNP with body composition and muscle loss. Read More

    Protected Mealtimes in hospitals and nutritional intake: Systematic review and meta-analyses.
    Int J Nurs Stud 2017 Jan 10;65:62-69. Epub 2016 Nov 10.
    Department of Nutrition & Dietetics, Monash University, Australia. Electronic address:
    Objectives: Protected Mealtimes is an intervention developed to address the problem of malnutrition, particularly in the hospital setting. The intervention aims to provide interruption-free time to eat during a hospital admission, thus supporting increased nutritional intake. This review aimed to determine the impact of Protected Mealtimes on the nutritional intake of hospitalised patients. Read More

    Prognostic significance of low skeletal muscle mass compared with protein-energy malnutrition in liver cirrhosis.
    Hepatol Res 2016 Nov 15. Epub 2016 Nov 15.
    Division of Hepatobiliary and Pancreatic disease, Department of Internal Medicine, Hyogo College of Medicine, Hyogo, Japan.
    Aims: To investigate the impact of low skeletal muscle mass (LSMM) on survival as compared with protein-energy malnutrition (PEM) in patients with liver cirrhosis (LC).

    Methods: A total of 206 individuals with LC were analyzed. We retrospectively examined the impact of LSMM, as defined by psoas muscle mass at the third lumber on computed tomography, on survival as compared with PEM. Read More

    Proximate composition and fatty acid analysis of Lablab purpureus (L.) legume seed: implicates to both protein and essential fatty acid supplementation.
    Springerplus 2016 28;5(1):1899. Epub 2016 Oct 28.
    Department of Environmental Physiology, Faculty of Medicine, Shimane University, Izumo, Shimane 693-8501 Japan.
    The high mortality rate in Bangladesh is related to poverty, which results in protein malnutrition, essential fatty acid deficiency and lacks in adequate vitamins, minerals and calorie. Exploring new food items with improved dietary nutrition factors may, therefore, help to decrease the mortality rate in the poor countries like Bangladesh. Accordingly, the present study was a proximate composition and fatty acid analysis of L. Read More

    Socioeconomic and Demographic Factors Influencing Feeding Practices, Morbidity Status, and Dietary Intakes of Children Aged 7-24 Months in Rural Uganda.
    Ecol Food Nutr 2017 Jan-Feb;56(1):1-16. Epub 2016 Nov 14.
    c Regional Centre for Quality Health Care , Makerere University , Kampala , Uganda.
    The objective of this study was to analyze the nutritional and morbidity patterns of children aged 7-24 months in relationship to household socioeconomic and demographic characteristics. Structured questionnaires and repeated 24-hour recalls were used to collect data. Maternal education and age influenced timing of complementary foods, dietary diversity score, meal frequency, and diarrhea incidences (p < . Read More

    Nutritional management in head and neck cancer: United Kingdom National Multidisciplinary Guidelines.
    J Laryngol Otol 2016 May;130(S2):S32-S40
    Department of Dietetics and Nutrition,QMC Campus,Nottingham University Hospitals NHS Trust,Nottingham,UK.
    Nutritional support and intervention is an integral component of head and neck cancer management. Patients can be malnourished at presentation, and the majority of patients undergoing treatment for head and neck cancer will need nutritional support. This paper summarises aspects of nutritional considerations for this patient group and provides recommendations for the practising clinician. Read More

    Targeting the underlying causes of undernutrition. Cost-effectiveness of a multifactorial personalized intervention in community-dwelling older adults: A randomized controlled trial.
    Clin Nutr 2016 Oct 15. Epub 2016 Oct 15.
    Department of Health Sciences and the EMGO+ Institute for Health and Care Research, Faculty of Earth and Life Sciences, Vrije Universiteit, Amsterdam, The Netherlands; Department of Nutrition and Dietetics, Internal Medicine, Vrije Universiteit Medical Center, Amsterdam, The Netherlands.
    Background & Aims: Undernutrition in old age is associated with increased morbidity, mortality and health care costs. Treatment by caloric supplementation results in weight gain, but compliance is poor in the long run. Few studies targeted underlying causes of undernutrition in community-dwelling older adults. Read More

    Effect of L-Carnitine in Patients With Liver Cirrhosis on Energy Metabolism Using Indirect Calorimetry: A Pilot Study.
    J Clin Med Res 2016 Dec 26;8(12):863-869. Epub 2016 Oct 26.
    Division of Hepatobiliary and Pancreatic Disease, Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya, Hyogo 663-8501, Japan.
    Background: L-carnitine supplementation has been suggested to show several favorable effects on patients with liver cirrhosis (LC). However, there have been no reports regarding the effect of L-carnitine on energy metabolism in patients with LC using indirect calorimetry which is a well-established method for assessing the degree of liver malnutrition. We examined the effect of L-carnitine in patients with LC on energy metabolism using indirect calorimetry. Read More

    Malnutrition at Intensive Care Unit Admission Predicts Mortality in Emergency General Surgery Patients.
    JPEN J Parenter Enteral Nutr 2016 Nov 7. Epub 2016 Nov 7.
    Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.
    Background: Emergency general surgery (EGS) patients are at an increased risk for morbidity and mortality compared with non-EGS patients. Limited information exists regarding the contribution of malnutrition to the outcome of critically ill patients who undergo EGS. We hypothesized that malnutrition would be associated with increased risk of 90-day all-cause mortality following intensive care unit (ICU) admission in EGS patients. Read More

    A Study on the Dietary Intake and the Nutritional Status among the Pancreatic Cancer Surgical Patients.
    Clin Nutr Res 2016 Oct 31;5(4):279-289. Epub 2016 Oct 31.
    Department of Nutritional Science and Food Management, Ewha Womans University, Seoul 03760, Korea .
    The adequate dietary intake is important to maintain the nutritional status of the patients after pancreatic cancer surgery. This prospective study was designed to investigate the dietary intake and the nutritional status of the patients who had pancreatic cancer surgery. Thirty-one patients (15 men, 16 women) were enrolled and measured body weight, body mass index (BMI), nutritional risk index (NRI), and Malnutrition Universal Screening Tool (MUST). Read More

    Protein- and zinc-deficient diets modulate the murine microbiome and metabolic phenotype.
    Am J Clin Nutr 2016 Nov 12;104(5):1253-1262. Epub 2016 Oct 12.
    University of Virginia Center for Global Health and.
    Background: Environmental enteropathy, which is linked to undernutrition and chronic infections, affects the physical and mental growth of children in developing areas worldwide. Key to understanding how these factors combine to shape developmental outcomes is to first understand the effects of nutritional deficiencies on the mammalian system including the effect on the gut microbiota.

    Objective: We dissected the nutritional components of environmental enteropathy by analyzing the specific metabolic and gut-microbiota changes that occur in weaned-mouse models of zinc or protein deficiency compared with well-nourished controls. Read More

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