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    9316 results match your criteria Protein-Energy Malnutrition

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    Prognostic impact of nutritional risk assessment in patients with chronic schizophrenia.
    Schizophr Res 2017 Apr 22. Epub 2017 Apr 22.
    Institute of Clinical Medicine, National Yang-Ming University, Taipei, Taiwan; Department of Psychiatry, Yuli Hospital, Ministry of Health and Welfare, Hualien, Taiwan. Electronic address:
    Protein-energy wasting is associated with poor outcome in various clinical settings. However, the prevalence of malnutrition and the prognostic impact of nutritional status are poorly understood in institutionalized patients with chronic schizophrenia. This study aimed to assess the predictive ability of the Geriatric Nutritional Risk Index and Onodera's Prognostic Nutritional Index for long-term outcomes in patients with chronic schizophrenia. Read More

    Systematic review on evidence-based adolescent nutrition interventions.
    Ann N Y Acad Sci 2017 Apr;1393(1):34-50
    Centre of Excellence in Women and Child Health, Aga Khan University, Karachi, Pakistan.
    Adolescence is a critical stage in the life cycle, and adequate nutrition is necessary for the proper growth and development of individuals and their offspring. Here, we comprehensively review all published systematic reviews (through October 2016) on adolescents (10-19 years) and women of reproductive age, including pregnant women, which targeted interventions related to nutrition. For interventions where there was no existing systematic review on adolescents, we reviewed primary studies/trials. Read More

    Nutritional Status Predicts 10-Year Mortality in Patients with End-Stage Renal Disease on Hemodialysis.
    Nutrients 2017 Apr 18;9(4). Epub 2017 Apr 18.
    Department of Food and Nutrition, Hanyang University, 222 Wangsimni-ro, Seongdong-gu, Seoul 04763, Korea.
    Protein-energy wasting (PEW) is associated with mortality in patients with end-stage renal disease (ESRD) on maintenance hemodialysis. The correct diagnosis of PEW is extremely important in order to predict clinical outcomes. However, it is unclear which parameters should be used to diagnose PEW. Read More

    Effects of high-fat diet on somatic growth, metabolic parameters and function of peritoneal macrophages of young rats submitted to a maternal low-protein diet.
    Br J Nutr 2017 Apr 17:1-8. Epub 2017 Apr 17.
    1Department of Nutrition,Federal University of Pernambuco,Recife, 50670-901, Brazil.
    This study evaluated the effects of a post-weaning high-fat (HF) diet on somatic growth, food consumption, metabolic parameters, phagocytic rate and nitric oxide (NO) production of peritoneal macrophages in young rats submitted to a maternal low-protein (LP) diet. Male Wistar rats (aged 60 d) were divided in two groups (n 22/each) according to their maternal diet during gestation and lactation: control (C, dams fed 17 % casein) and LP (dams fed 8 % casein). At weaning, half of the groups were fed HF diet and two more groups were formed (HF and low protein-high fat (LP-HF)). Read More

    The Diet and Haemodialysis Dyad: Three Eras, Four Open Questions and Four Paradoxes. A Narrative Review, Towards a Personalized, Patient-Centered Approach.
    Nutrients 2017 Apr 10;9(4). Epub 2017 Apr 10.
    Nefrologia, Università di Pisa, 56100 Italy.
    The history of dialysis and diet can be viewed as a series of battles waged against potential threats to patients' lives. In the early years of dialysis, potassium was identified as "the killer", and the lists patients were given of forbidden foods included most plant-derived nourishment. As soon as dialysis became more efficient and survival increased, hyperphosphatemia, was identified as the enemy, generating an even longer list of banned aliments. Read More

    Vegetarian Diet in Chronic Kidney Disease-A Friend or Foe.
    Nutrients 2017 Apr 10;9(4). Epub 2017 Apr 10.
    Department of Nephrology, Hypertension and Family Medicine, Medical University of Lodz, Zeromskiego 113, 90-549 Lodz, Poland.
    Healthy diet is highly important, especially in patients with chronic kidney disease (CKD). Proper nutrition provides the energy to perform everyday activities, prevents infection, builds muscle, and helps to prevent kidney disease from getting worse. However, what does a proper diet mean for a CKD patient? Nutrition requirements differ depending on the level of kidney function and the presence of co-morbid conditions, including hypertension, diabetes, and cardiovascular disease. Read More

    Protein Requirements of the Critically Ill Pediatric Patient.
    Nutr Clin Pract 2017 Apr 1;32(1_suppl):128S-141S. Epub 2017 Mar 1.
    6 Division of General Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA.
    This article includes a review of protein needs in children during health and illness, as well as a detailed discussion of protein metabolism, including nitrogen balance during critical illness, and assessment and prescription/delivery of protein to critically ill children. The determination of protein requirements in children has been difficult and challenging. The protein needs in healthy children should be based on the amount needed to ensure adequate growth during infancy and childhood. Read More

    How Much and What Type of Protein Should a Critically Ill Patient Receive?
    Nutr Clin Pract 2017 Apr 1;32(1_suppl):6S-14S. Epub 2017 Mar 1.
    7 Department of Medicine, University of Louisville, Louisville, Kentucky, USA.
    Protein loss, manifested as loss of muscle mass, is observed universally in all critically ill patients. Depletion of muscle mass is associated with impaired function and poor outcomes. In extreme cases, protein malnutrition is manifested by respiratory failure, lack of wound healing, and immune dysfunction. Read More

    Nutritional assessment of elderly patients on dialysis: pitfalls and potentials for practice.
    Nephrol Dial Transplant 2017 Mar 22. Epub 2017 Mar 22.
    Nutrition Institute, Rio de Janeiro, Brazil.
    The chronic kidney disease (CKD) population is aging. Currently a high percentage of patients treated on dialysis are older than 65 years. As patients get older, several conditions contribute to the development of malnutrition, namely protein energy wasting (PEW), which may be compounded by nutritional disturbances associated with CKD and from the dialysis procedure. Read More

    How to measure energy and protein intake in a geriatric department - A comparison of three visual methods.
    Clin Nutr ESPEN 2017 Feb 27;17:110-113. Epub 2016 Oct 27.
    Department of Geriatric Medicine, Odense University Hospital, Sdr. Boulevard 29, DK-5000 Odense C, Denmark.
    Background & Aims: Sufficient energy and protein intake are essential to treatment and recovery of hospitalized older adults. The food intake should be assessed in order to detect patients in need of nutritional intervention. The aim of this study was to compare the accuracy of three visual methods for assessing energy and protein intake as compared to weighing food items. Read More

    Using stable isotope techniques in nutrition assessments and tracking of global targets post-2015.
    Proc Nutr Soc 2017 Mar 28:1-9. Epub 2017 Mar 28.
    Nutritional and Health-Related Environmental Studies Section,Division of Human Health,International Atomic Energy Agency, Vienna International Centre,PO Box 100,1400 Vienna,Austria.
    Stable isotopes are non-radioactive, safe and are applied for various purposes in human health assessment in trace amounts that minimally disturb normal physiology. The International Atomic Energy Agency supports the use of stable isotope techniques to design and evaluate interventions addressing malnutrition in all its forms with focus on infant and young child feeding; maternal and adolescent nutrition; diet quality; prevention and control of non-communicable diseases; healthy ageing and gut function. These techniques can be used to objectively measure: (1) amount of human milk consumed and whether an infant is exclusively breastfed; (2) body composition in the context of re-feeding programmes for moderate and severe acute malnutrition and as an indicator of the risk for obesity; (3) bioavailability and bioconversion of pro-vitamin A and vitamin A body stores following vitamin A intervention programmes; (4) absorption and retention of iron, zinc and protein; (5) total energy expenditure for validation of physical activity measurement and dietary assessment tools and (6) diagnosis of Helicobacter pylori. Read More

    Patients With Mitochondrial Disease Have an Inadequate Nutritional Intake.
    JPEN J Parenter Enteral Nutr 2017 Mar 1:148607117699792. Epub 2017 Mar 1.
    1 Radboud Center for Mitochondrial Medicine, Radboudumc, Nijmegen, The Netherlands.
    Background: Mitochondrial disease (MD) is a group of disorders caused by dysfunctional mitochondria, the organelles that generate energy for the cell. Malnutrition in patients with MD may lead to increased mitochondrial dysfunction, which may enhance already existing symptoms. The aim of this study was to investigate whether patients with MD have an insufficient or unbalanced food intake and to establish which nutrients and product groups are particularly compromised in this patient group. Read More

    The UN Decade of Nutrition, the NOVA food classification and the trouble with ultra-processing.
    Public Health Nutr 2017 Mar 21:1-13. Epub 2017 Mar 21.
    1Department of Nutrition,School of Public Health,University of São Paulo,Av. Dr Arnaldo 715,São Paulo 01246-904,Brazil.
    Given evident multiple threats to food systems and supplies, food security, human health and welfare, the living and physical world and the biosphere, the years 2016-2025 are now designated by the UN as the Decade of Nutrition, in support of the UN Sustainable Development Goals. For these initiatives to succeed, it is necessary to know which foods contribute to health and well-being, and which are unhealthy. The present commentary outlines the NOVA system of food classification based on the nature, extent and purpose of food processing. Read More

    Impact of Nutritional Intervention on Length of Hospital Stay and Mortality among Hospitalized Patients with Malnutrition: A Clinical Randomized Controlled Trial.
    J Am Coll Nutr 2017 Mar 20:1-5. Epub 2017 Mar 20.
    b Biomedical Research Unit of the Mexican Social Security Institute at Durango , Durango , Dgo. , México.
    Objective: The objective of this study was to evaluate the impact of a nutritional intervention on hospital stay and mortality among hospitalized patients with malnutrition.

    Methods: Hospitalized patients with a diagnosis of malnutrition were enrolled and randomly allocated to either an intervention or control group. Participants in the intervention group received an individualized nutrition plan according to energy and protein (1. Read More

    Intrauterine Growth Restriction Programs the Hypothalamus of Adult Male Rats: Integrated Analysis of Proteomic and Metabolomic Data.
    J Proteome Res 2017 Apr 30;16(4):1515-1525. Epub 2017 Mar 30.
    Department of Physiology, Universidade Federal de São Paulo UNIFESP , São Paulo, SP 04021-001, Brazil.
    Programming of hypothalamic functions regulating energy homeostasis may play a role in intrauterine growth restriction (IUGR)-induced adulthood obesity. The present study investigated the effects of IUGR on the hypothalamus proteome and metabolome of adult rats submitted to 50% protein-energy restriction throughout pregnancy. Proteomic and metabolomic analyzes were performed by data independent acquisition mass spectrometry and multiple reaction monitoring, respectively. Read More

    Relationship between pickiness and subsequent development in body mass index and diet intake in obesity prone normal weight preschool children.
    PLoS One 2017 15;12(3):e0172772. Epub 2017 Mar 15.
    Research Unit for Dietary Studies at The Parker Institute, Bispebjerg and Frederiksberg University Hospital, The Capital Region, Frederiksberg, Denmark.
    Background: Most children have periods in their life where they reject familiar as well as non-familiar food items and this is often referred to as pickiness. The consequences of pickiness may be malnutrition and, if prolonged, potentially lower body weight. However, studies investigating the consequence of pickiness on subsequent changes in diet intake and weight are limited. Read More

    Role of domiciliary and family carers in individualised nutrition support for older adults living in the community.
    Maturitas 2017 Apr 12;98:20-29. Epub 2017 Jan 12.
    Faculty of Health Sciences and Medicine, Bond University, Robina, Queensland, 4226, Australia; Department of Nutrition and Dietetics, Princess Alexandra Hospital, Woolloongabba, Queensland 4102, Australia.
    Protein-energy malnutrition is common amongst people aged 65 years and older, has a multifactorial aetiology, and numerous negative outcomes. Domiciliary carers (non-clinical paid carers) and family carers (including family, friends and neighbours) are required to support the increasing demand for in-home assistance with activities of daily living due to the ageing population. This review provides insight into the role of both domiciliary and family carers in providing individualised nutrition support for older, community-dwelling adults with malnutrition. Read More

    Protein Nutrition and Malnutrition in CKD and ESRD.
    Nutrients 2017 Feb 27;9(3). Epub 2017 Feb 27.
    Division of Nephrology and Hypertension, Department of Medicine, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA.
    Elevated protein catabolism and protein malnutrition are common in patients with chronic kidney disease (CKD) and end-stage renal disease (ESRD). The underlying etiology includes, but is not limited to, metabolic acidosis intestinal dysbiosis; systemic inflammation with activation of complements, endothelin-1 and renin-angiotensin-aldosterone (RAAS) axis; anabolic hormone resistance; energy expenditure elevation; and uremic toxin accumulation. All of these derangements can further worsen kidney function, leading to poor patient outcomes. Read More

    Health insurance or subsidy has universal advantage for management of hospital malnutrition unrelated to GDP.
    Asia Pac J Clin Nutr 2017 Mar;26(2):247-254
    Jagiellonian University Medical College, Chair of Epidemiology and Preventive Medicine, Department of Epidemiology, Krakow, Poland.
    Background And Objectives: Protein-energy and micronutrient malnutrition are global public health problems which, when not prevented and severe, require medical management by clinicians with nutrition expertise, preferably as a collectively skilled team, especially when disease-related. This study aimed to investigate barriers and facilitators of clinical nutrition services (CNS), especially the use of oral, enteral (EN) and parenteral (PN) nutrition in institutional and home settings.

    Methods And Study Design: An international survey was performed between January and December 2014 in twenty-six countries from all continents. Read More

    Serum zinc evolution in dysphagic patients that underwent endoscopic gastrostomy for long term enteral feeding.
    Asia Pac J Clin Nutr 2017 Mar;26(2):227-233
    Centro de Estudos de Doenças Crónicas, CEDOC, NOVA Medical School / Faculdade de Ciências Médicas, Universidade Nova de Lisboa, Lisbon, Portugal.
    Background And Objectives: Patients undergoing endoscopic gastrostomy (PEG) present with protein-energy malnutrition (PEM) but little is known about zinc status. Our aim was to evaluate serum zinc, its relationship with serum proteins and with the nature of the underlying disorder, during the first 3 months of PEG feeding.

    Methods And Study Design: Prospective observational study during a 3-month period after gastrostomy. Read More

    The Impact of Trained Volunteer Mealtime Assistants on the Dietary Intake of Older Female In-Patients: The Southampton Mealtime Assistance Study.
    J Nutr Health Aging 2017 ;21(3):320-328
    Dr Helen Roberts, Academic Geriatric Medicine Mailpoint 807, Southampton General Hospital, Southampton SO16 6YD, Tel: 023 8120 4354 Email :
    Objective: Malnutrition among older hospital inpatients is common and is associated with poor clinical outcomes. Time-pressured staff may struggle to provide mealtime assistance. This study aimed to evaluate the impact of trained volunteer mealtime assistants on the dietary intake of older inpatients. Read More

    Rehabilitation and nutritional support for sarcopenic dysphagia and tongue atrophy after glossectomy: A case report.
    Nutrition 2017 Mar 22;35:128-131. Epub 2016 Nov 22.
    Department of Otolaryngology, Head and Neck Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka City, Japan.
    Swallowing dysfunction is related to long-term weight loss and reduced body mass index in patients with head and neck cancer. We describe a 76-y-old woman who had severe sarcopenic dysphagia and atrophy of the reconstructed tongue for 17 mo after subtotal glossectomy due to tongue cancer and lost 14 kg during that period. Upon admission, the patient received diagnoses of malnutrition in the context of social or environmental circumstances with insufficient energy intake, loss of muscle mass, localized fluid accumulation, weight loss, and sarcopenia due to reduced skeletal muscle mass (skeletal muscle index <3. Read More

    Performance of subjective global assessment and malnutrition inflammation score for monitoring the nutritional status of older adults on hemodialysis.
    Clin Nutr 2017 Feb 3. Epub 2017 Feb 3.
    Nutrition Institute, Rio de Janeiro State University, Rio de Janeiro, Brazil. Electronic address:
    Background & Aims: Studies assessing the performance of 7-point subjective global assessment (7p-SGA) and malnutrition inflammation score (MIS) to assess longitudinal changes in nutritional status are lacking. Thus, we aimed to investigate whether longitudinal changes in 7p-SGA and MIS were associated with changes in objective parameters of nutritional status, as well as to evaluate the prognostic value of 7p-SGA and MIS on hospitalization events.

    Methods: One hundred and four patients aged ≥60 years (70. Read More

    Evidence-based interventions for improvement of maternal and child nutrition in low-income settings: what's new?
    Curr Opin Clin Nutr Metab Care 2017 May;20(3):204-210
    aCentre for Global Child Health, The Hospital for Sick Children, Toronto, Ontario, Canada bCentre of Excellence in Women and Child Health, Aga Khan University, Karachi, Pakistan.
    Purpose Of Review: Maternal and child malnutrition continues to disproportionately affect low and middle-income countries, contributing to high rates of morbidity, mortality, and suboptimal development. This article reviews evidence from recent systematic reviews and studies on the effectiveness of interventions to improve nutritional status in these especially vulnerable populations.

    Recent Findings: Macronutrients provided to expectant mothers in the form of balanced protein energy supplements can improve fetal growth and birth outcomes, and new research suggests that lipid nutrient supplements can reduce both stunting and wasting in newborns. Read More

    Parallel changes in cortical neuron biochemistry and motor function in protein-energy malnourished adult rats.
    Neuroimage 2017 Apr 4;149:275-284. Epub 2017 Feb 4.
    Neuroscience Research Group, Department of Anatomy and Cell Biology and College of Pharmacy and Nutrition University of Saskatchewan, D Wing GD30 (Box 1) Health Sciences, 107 Wiggins Road, Saskatoon, SK, Canada, S7N 5E5; College of Pharmacy and Nutrition, Canada; Cameco MS Neuroscience Center, University of Saskatchewan, Saskatoon, Canada. Electronic address:
    While protein-energy malnutrition in the adult has been reported to induce motor abnormalities and exaggerate motor deficits caused by stroke, it is not known if alterations in mature cortical neurons contribute to the functional deficits. Therefore, we explored if PEM in adult rats provoked changes in the biochemical profile of neurons in the forelimb and hindlimb regions of the motor cortex. Fourier transform infrared spectroscopic imaging using a synchrotron generated light source revealed for the first time altered lipid composition in neurons and subcellular domains (cytosol and nuclei) in a cortical layer and region-specific manner. Read More

    Relationship between epigenetic regulation, dietary habits, and the developmental origins of health and disease theory.
    Congenit Anom (Kyoto) 2017 Feb 7. Epub 2017 Feb 7.
    Laboratory of Nutritional Physiology, Graduate School of Nutritional and Environmental Sciences, University of Shizuoka, Shizuoka, Japan.
    Environmental stressors during developmental stages are hypothesized to increase the risk of developing metabolic diseases such as obesity, type 2 diabetes, hypertension, and psychiatric diseases during later life. This theory is known as the Developmental Origins of Health and Disease (DOHaD). Recent studies suggest that accumulation of environmental stress, including those during developmental stages, is internalized as acquired information designated as "epigenetic memory. Read More

    Biofortification in Millets: A Sustainable Approach for Nutritional Security.
    Front Plant Sci 2017 23;8:29. Epub 2017 Jan 23.
    T. A. Lourdusamy Unit for Plant Tissue Culture and Molecular Biology, Department of Plant Biology and Biotechnology, Loyola College Chennai, India.
    Nutritional insecurity is a major threat to the world's population that is highly dependent on cereals-based diet, deficient in micronutrients. Next to cereals, millets are the primary sources of energy in the semi-arid tropics and drought-prone regions of Asia and Africa. Millets are nutritionally superior as their grains contain high amount of proteins, essential amino acids, minerals, and vitamins. Read More

    The efficacy of Protected Mealtimes in hospitalised patients: a stepped wedge cluster randomised controlled trial.
    BMC Med 2017 Feb 7;15(1):25. Epub 2017 Feb 7.
    Department of Nutrition, Dietetics and Food, Monash University, 264 Ferntree Gully Road, Notting Hill, Victoria, 3168, Australia.
    Background: Protected Mealtimes is an intervention developed to address the problem of malnutrition in hospitalised patients through increasing positive interruptions (such as feeding assistance) whilst minimising unnecessary interruptions (including ward rounds and diagnostic procedures) during mealtimes. This clinical trial aimed to measure the effect of implementing Protected Mealtimes on the energy and protein intake of patients admitted to the subacute setting.

    Methods: A prospective, stepped wedge cluster randomised controlled trial was undertaken across three hospital sites at one health network in Melbourne, Australia. Read More

    Nutrition, frailty, and sarcopenia.
    Aging Clin Exp Res 2017 Feb 2;29(1):43-48. Epub 2017 Feb 2.
    Institute for Biomedicine of Aging, University of Erlangen-Nürnberg, Nuremberg, Germany.
    Frailty and sarcopenia are important concepts in the quest to prevent physical dependence, as geriatrics are shifting towards identifications of early stages of disability. Definitions of both sarcopenia and frailty are still developing, and both concepts clearly overlap in their physical aspects. Malnutrition (both undernutrition and obesity) plays a key role in the pathogenesis of frailty and sarcopenia. Read More

    From Evidence to Clinical Practice.
    Nutr Clin Pract 2017 Jan 1:884533616688432. Epub 2017 Jan 1.
    4 Abdominal Centre, Rigshospital, Copenhagen University Hospital, Copenhagen, Denmark.
    Background: The aim of this study was to investigate if a protein-enriched menu in conjunction with individualized dietary counseling would increase energy and protein intake in hospitalized patients at nutrition risk compared with providing the protein-enriched menu as a stand-alone intervention.

    Method: Data from medical and surgical hospitalized patients were prospectively collected and compared with a historical intervention group (HIG). Primary outcome was the number of patients achieving >75% of energy and protein requirements. Read More

    Resting energy expenditure in the risk assessment of anticancer treatments.
    Clin Nutr 2017 Jan 19. Epub 2017 Jan 19.
    Medical Oncology Department, Cancer Research for Personalized Medicine (CARPEM), Paris Centre Teaching Hospitals, Paris Descartes University, USPC, Paris, France.
    Background & Aims: Alterations of nutritional and performance status (PS) are associated with higher risk of chemotherapy toxicity. Increased resting energy expenditure (REE) is frequent in cancer patients and may contribute to cachexia. We investigated whether abnormal energetic metabolism could predict early acute limiting toxicities (ELT) of anticancer treatments. Read More

    ESPEN guideline: Clinical nutrition in inflammatory bowel disease.
    Clin Nutr 2017 Apr 31;36(2):321-347. Epub 2016 Dec 31.
    Institut für Ernährungsmedizin (180) Universität Hohenheim, Fruwirthstr. 12, 70593 Stuttgart, Germany. Electronic address:
    Introduction: The ESPEN guideline presents a multidisciplinary focus on clinical nutrition in inflammatory bowel disease (IBD).

    Methodology: The guideline is based on extensive systematic review of the literature, but relies on expert opinion when objective data were lacking or inconclusive. The conclusions and 64 recommendations have been subject to full peer review and a Delphi process in which uniformly positive responses (agree or strongly agree) were required. Read More

    The Effects of Compliance with Nutritional Counselling on Body Composition Parameters in Head and Neck Cancer Patients under Radiotherapy.
    J Nutr Metab 2017 1;2017:8631945. Epub 2017 Jan 1.
    Department of Anesthesiology and Intensive Care, Ege University School of Medicine, Bornova, 35100 Izmir, Turkey.
    Background. Radiotherapy (RT) has been associated with increased risk of malnutrition in cancer patients, particularly in those with head and neck cancer (HNC). The aim of this prospective study was to evaluate the effects of compliance of patients with individual dietary counselling on body composition parameters in HNC patients under RT. Read More

    Prognostic significance of nonprotein respiratory quotient in patients with liver cirrhosis.
    Medicine (Baltimore) 2017 Jan;96(3):e5800
    Division of Hepatobiliary and Pancreatic Disease, Department of Internal Medicine, Hyogo College of Medicine, Hyogo, Japan.
    The aim of this study was to examine the effect of nonprotein respiratory quotient (npRQ), as assessed using indirect calorimetry, on clinical outcomes in patients with liver cirrhosis (LC). A total of 244 LC patients were evaluated in this study. For the univariate analysis, for each continuous variable, the optimal cutoff value that maximized the sum of sensitivity and specificity was selected using receiver operating curve (ROC) analysis for survival. Read More

    Low-dose dialysis combined with low protein intake can maintain nitrogen balance in peritoneal dialysis patients in poor economies
    Clin Nephrol 2017 Feb;87 (2017)(2):84-92
    Objective: Due to limited economic conditions, we tried to provide "fitted" dialysis doses instead of the doses recommended by the international guidelines to the individual patients. In the present cross-sectional study, we studied the dialysis adequacy and nutritional status of 5 peritoneal dialysis patients who had a low dialysis dose (2 bags, 4,000 mL/day).

    Methods: The 3-day dietary records were reviewed to calculate patients' energy, protein, and nitrogen intake (NI). Read More

    Previous Repeated Exposure to Food Limitation Enables Rats to Spare Lipid Stores during Prolonged Starvation.
    Physiol Biochem Zool 2017 Jan/Feb;90(1):63-74. Epub 2016 Nov 7.
    The risk of food limitation and, ultimately, starvation dates back to the dawn of heterotrophy in animals, yet starvation remains a major factor in the regulation of modern animal populations. Researchers studying starvation more than a century ago suggested that animals subjected to sublethal periods of food limitation are somehow more tolerant of subsequent starvation events. This possibility has received little attention over the past decades, yet it is highly relevant to modern science for two reasons. Read More

    Maternal undernutrition programs the apelinergic system of adipose tissue in adult male rat offspring.
    J Dev Orig Health Dis 2017 Feb;8(1):3-7
    1EA4489,Équipe Malnutrition Maternelle et Programmation des Maladies Métaboliques,Univ. Lille,Lille,France.
    Based on the Developmental Origin of Health and Disease concept, maternal undernutrition has been shown to sensitize adult offspring to metabolic pathologies such as obesity. Using a model of maternal 70% food restriction in pregnant female rats throughout gestation (called FR30), we previously reported that obesity-prone adult male rat offspring displayed hyperleptinemia with modifications in leptin and leptin receptor messenger RNA (mRNA) levels in white adipose tissue (WAT). Apelin is a member of the adipokine family that regulates various aspects of energy metabolism and WAT functionality. Read More

    A rapid assessment and response approach for socially marketed nutrition commodities in Viet Nam.
    Asia Pac J Clin Nutr 2017 Jan;26(1):182-189
    National Institute for Nutrition (NIN), Ha Noi, Vietnam.
    Background: The leading cause of death in children in developing countries is protein-energy malnutrition. In Viet Nam, 25.9% of children under 5 experience stunted growth and 6. Read More

    Nutrition assessment and its relationship with performance and Glasgow prognostic scores in Vietnamese patients with esophageal cancer.
    Asia Pac J Clin Nutr 2017 Jan;26(1):49-58
    National Cancer Hospital, Hanoi, Vietnam.
    Background And Objectives: To determine the nutritional status of patients with esophageal cancer, and to investigate its relationship with performance status and prognosis.

    Methods And Study Design: This clinical, cross-sectional study was conducted from August 2014 to February 2015 at National Cancer Hospital, Hanoi, Vietnam. Stage III/IV esophageal cancer patients were assessed for their nutritional status (patient-generated subjective global assessment (PG-SGA) and SGA scores, BMI, mid-arm circumference (MAC), energy and protein intakes, weight changes, Karnofsky and Eastern cooperative oncology group performance scores (KPS/ECOG), and Glasgow prognostic score (GPS). Read More

    Relationship of aging and nutritional status to innate immunity in tube-fed bedridden patients.
    Asia Pac J Clin Nutr 2017 Jan;26(1):36-41
    Department of Internal Medicine, Division of Gastroenterology, Showa University School of Medicine, Shinagawa-ku, Tokyo, Japan.
    Background And Objectives: Aging and malnutrition are known to influence immune functions. The aim of this study was to investigate the relationship of aging and malnutrition to innate immune functions in tube-fed bedridden patients.

    Methods And Study Design: A cross-sectional survey was performed in 71 tube-fed bedridden patients aged 50-95 years (mean age±SD, 80. Read More

    Nutrient composition of premixed and packaged complementary foods for sale in low- and middle-income countries: Lack of standards threatens infant growth.
    Matern Child Nutr 2016 Dec 22. Epub 2016 Dec 22.
    Friedman School of Nutrition Science and Policy, Tufts University, Boston, Massachusetts, USA.
    Premixed flours for infant porridge are increasingly produced and sold in developing countries to complement continued breastfeeding. Such complementary food (CF) products have known efficacy against malnutrition in children from 6 to 24 months of age, but ingredient ratios and production processes may vary. This study provides the first systematic measurement of their actual nutrient composition. Read More

    Keto-analogues and essential aminoacids and other supplements in the conservative management of chronic kidney disease.
    Panminerva Med 2017 Jun 21;59(2):149-156. Epub 2016 Dec 21.
    Territorial Department of Nephrology and Dialysis, ASL 8, Cagliari, Italy.
    The manipulation of dietary protein intake is the mainstay of nutritional treatment of patients affected by chronic renal insufficiency, with the aim to reduce the burden of uremic toxins in order to decrease uremic toxicity and delay the need for dialysis. Consensus exists regarding the benefit of progressive protein restriction towards delaying the progression of renal failure and the need for dialysis, provided adequate energy supply. Although pivotal, protein restriction is only one aspect of the dietary management of chronic kidney disease (CKD) patients. Read More

    A short nutritional intervention in a cohort of hematological inpatients improves energy and protein intake and stabilizes nutritional status.
    Nutr Hosp 2016 Nov 29;33(6):1347-1353. Epub 2016 Nov 29.
    Clinical Nutrition and Dietetics Unit. Department of Endocrinology and Nutrition, Complejo Asistencial Universitario de León. León.
    Introduction: Oncohematological diseases are associated with an important prevalence of malnutrition.

    Aim: Our aim is to determine if early recognition and treatment of malnourished hematological inpatients can improve their oral intake, nutritional status and reduce the length of hospital stay.

    Methods: Prospective 2-year study conducted in a cohort of hematology inpatients. Read More

    Dilated Cardiomyopathy Induced by Chronic Starvation and Selenium Deficiency.
    Case Rep Pediatr 2016 22;2016:8305895. Epub 2016 Nov 22.
    Department of Pediatric Cardiology, University of Texas Medical Branch, Galveston, TX 77555, USA.
    Protein energy malnutrition (PEM) has been rarely documented as a cause of cardiovascular abnormalities, including dilated cardiomyopathy. Selenium is responsible for antioxidant defense mechanisms in cardiomyocytes, and its deficiency in the setting of PEM and disease related malnutrition (DRM) may lead to exacerbation of the dilated cardiomyopathy. We report a rare case of a fourteen-year-old boy who presented with symptoms of congestive heart failure due to DRM and PEM (secondary to chronic starvation) along with severe selenium deficiency. Read More

    Communication: Homocysteine, Thioretinaco Ozonide, Oxidative Phosphorylation, Biosynthesis of Phosphoadenosine Phosphosulfate and the Pathogenesis of Atherosclerosis.
    Ann Clin Lab Sci 2016 Dec;46(6):701-704
    Pathology and Laboratory Medicine Service, Boston Veterans Affairs Healthcare System, and Department of Pathology, Harvard Medical School, Boston, MA, USA
    The formation of phosphoadenosine phosphosulfate (PAPS) is accomplished by the action of the enzyme 3'-phosphoadenosine 5'-phosphosulfate synthase (PAPSS) in two sequential reactions, consisting of (1) reaction of inorganic sulfate with adenosine triphosphate (ATP) to form adenosine phosphosulfate (APS) and pyrophosphate and (2) reaction of APS with inorganic phosphate to form PAPS and adenosine diphosphate (ADP). The hydrolysis of guanosine triphosphate (GTP) is coordinated with synthesis of APS in a reaction sequence which provides the chemical energy for synthesis of APS. The present proposal is that the active site of oxidative phosphorylation, thioretinaco ozonide oxygen (TR2CoO3O2), functions as the source of APS synthesis from nicotinamide adenine dinucleotide (NAD(+)) and hydrosulfate (HSO4(-)) by reduction of the complex with electrons from electron transport complexes, releasing APS and thioretinaco hydroperoxide (TR2CoO3O2H) upon protonation. Read More

    A foodservice approach to enhance energy intake of elderly subacute patients: a pilot study to assess impact on patient outcomes and cost.
    Age Ageing 2016 Dec 14. Epub 2016 Dec 14.
    Department of Nutrition and Dietetics, Monash University, Level 1, 264 Ferntree Gully Road , Notting Hill, Victoria 3168, Australia.
    Background: effective strategies are required to support the nutritional status of patients.

    Objectives: to evaluate a foodservice nutrition intervention on a range of participant outcomes and estimate its cost.

    Design: parallel controlled pilot study. Read More

    Nutrient deficiencies prior to bariatric surgery.
    Curr Opin Clin Nutr Metab Care 2017 Mar;20(2):138-144
    aDivisions of Endocrinology bGastroenterology and Hepatology, Mayo Clinic, Scottsdale, Arizona, USA.
    Purpose Of Review: The purpose of this review is to provide an update of recent additions to our understanding of the prevalence of nutrient deficiencies and the potential role of preoperative weight loss in contributing to these deficiencies in obese individuals planning to undergo bariatric surgery.

    Recent Findings: Recent reports that have included bariatric surgery candidates from sites around the world have shown consistent deficiencies in a variety of nutrients. Although protein-energy malnutrition is uncommon preoperatively, micronutrient deficiencies occur commonly with multiple deficiencies often present in the same individual. Read More

    Older patients' use of technology for a post-discharge nutritional intervention - A mixed-methods feasibility study.
    Int J Med Inform 2017 Jan 6;97:312-321. Epub 2016 Nov 6.
    Copenhagen University Hospital, Department of Internal Medicine, Herlev Ringvej 75, DK-2730 Herlev, Denmark. Electronic address:
    Background: Malnutrition is frequent in older people and a precursor for morbidity and hospitalisation; furthermore low intake and weight loss during and after hospitalisation is well-described. Such patients are often excluded from technology projects on account of lack of skills. This is a barrier for their access to many current and future health care offers. Read More

    Nutritional supplementation for hip fracture aftercare in older people.
    Cochrane Database Syst Rev 2016 Nov 30;11:CD001880. Epub 2016 Nov 30.
    Health Services Research Unit, School of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Health Sciences Building, Foresterhill, Aberdeen, UK, AB25 2ZD.
    Background: Older people with hip fractures are often malnourished at the time of fracture, and subsequently have poor food intake. This is an update of a Cochrane review first published in 2000, and previously updated in 2010.

    Objectives: To review the effects (benefits and harms) of nutritional interventions in older people recovering from hip fracture. Read More

    The Effect of BCAA and ISO-WHEY Oral Nutritional Supplements on Dialysis Adequacy.
    Nephrourol Mon 2016 Nov 5;8(6):e34993. Epub 2016 Sep 5.
    Faculty of Physical Education and Sport Sciences, Shahid Rajaee Teacher Training University, Tehran, IR Iran.
    Background: Protein-energy malnutrition is a common problem in hemodialysis patients and has different outcomes such as reduced quality of life, longer hospitalization time, lower dialysis adequacy, and higher mortality rate. Investigation of dialysis adequacy is an important method for assessing hemodialysis patients, and improving the dialysis adequacy is an important healthcare team goal.

    Objectives: The present study aims to investigate and compare the effects of BCAA and ISO-WHEY oral nutritional supplements on dialysis adequacy. Read More

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