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    9557 results match your criteria Protein-Energy Malnutrition

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    Percutaneous Endoscopic Gastrostomy in Ile-Ife, Nigeria:An Initial Report.
    West Afr J Med 2018 Jan-Apr;35(1):47-52
    Department of surgery,Obafemi Awolowo University Teaching Hospital Complex, PMB 5538, Ile-Ife, Osun State, Nigeria.
    Background: Protein-energy malnutrition is a common problem in critically ill patient and it is a major cause of accelerated morbidity and mortality in this group of patients. Recent dramatic advances in both enteral and parenteral nutritional support have ensured that most of these critically ill patients are adequately nutritionally supported. Unfortunately, most of these advancements in nutritional supports are far from the reach of most patients in developing countries. Read More

    [Milk, Daily products and Bone health.Nutritional Value of Milk and Dairy Products.]
    Clin Calcium 2018 ;28(4):483-491
    Faculty of Nutrition, Kagawa Nutrition University, Sakado, Japan.
    Milk has been historically recognized as having great nutritional value;its high nutrient density per energy makes it useful for individuals recovering from malnutrition among others. Milk is composed of an excellent ratio of essential amino acids, with an amino acid score of 100, and enhances the protein content when served with a meal. Additionally, not only is milk rich in calcium, but the absorption rate of calcium contained in the meal increases when milk is served with a meal. Read More

    Global nutrition 1990-2015: A shrinking hungry, and expanding fat world.
    PLoS One 2018 27;13(3):e0194821. Epub 2018 Mar 27.
    Department of Human Nutrition and Metabolism, Braun School of Public Health, Hebrew University Hadassah Medical School, Jerusalem, Israel.
    Objectives: Following its publication in 2008, the Global Nutritional Index (GNI) which captures the triple burden of malnutrition, has been updated to assess the overall nutritional status and nutritional trends of countries, regions and the world, including both under-nutrition and over-nutrition.

    Methods: The GNI was modeled on the Human Development Index, using geometric means of three normalized indicators: protein-energy malnutrition (PEM, measured by Disability-Adjusted Life Years (DALYs) from PEM), micronutrient deficiency (MID, measured by DALYs from MID), and penalizing obesity (percent female obesity). GNI (range 0-1) was calculated from 1990-2015 for 186 countries, in seven World Bank income and WHO region groupings. Read More

    Identifying reliable predictors of protein-energy malnutrition in hospitalized frail older adults. A prospective longitudinal study.
    Int J Nurs Stud 2018 Mar 7;82:40-48. Epub 2018 Mar 7.
    School of Nursing, Dept. of Medical Science, University of Trieste, piazzale Valmaura 9, 34148, Trieste, Italy; Nutrition Team, Trieste University Hospital, Strada di Fiume 447, 34149, Trieste, Italy. Electronic address:
    Background: Decreased food intake is a risk factor for relevant complications (e.g. infections, pressure ulcers), longer hospital stays, higher readmission rates, greater health care costs and increased patient mortality, particularly in frail hospitalized older adults who are malnourished or at risk of malnutrition. Read More

    Improving nutrition care and intake for older hospital patients through system-level dietary and mealtime interventions.
    Clin Nutr ESPEN 2018 Apr 3;24:140-147. Epub 2018 Jan 3.
    Dept of Internal Medicine and Aged Care, Royal Brisbane and Women's Hospital, Butterfield St, Herston 4029, Australia.
    Background & Aims: Interventions such as oral nutritional supplements (ONS), fortified meals and mid-meals, feeding assistants and Protected Mealtimes have shown some impact on nutritional intake in research studies, but embedding them in practise remains challenging. This study monitored nutritional intake of older medical inpatients as dietary and mealtime interventions were progressively implemented into routine practise.

    Methods: Series of three prospectively evaluated patient cohorts allowed comparison of nutritional intake of 320 consented medical inpatients aged 65 + years: cohort 1 (2007-8), cohort 2 (2009) and cohort 3 (2013-14) as nutrition care interventions were progressively introduced and embedded. Read More

    A preclinical study to model taurine pharmokinetics in the undernourished rat.
    Br J Nutr 2018 Apr;119(7):826-835
    1Department of Pharmacy and Pharmaceutical Technology and Parasitology,University of Valencia,46100 Burjassot, Valencia, Spain.
    Malnutrition is a common feature of chronic and acute diseases, often associated with a poor prognosis, including worsening of clinical outcome, owing, among other factors, to dysfunction of the most internal organs and systems affecting the absorption, metabolism and elimination of drugs and nutrients. Taurine is involved in numerous biological processes and is required in increased amounts in response to pathological conditions. The aim of this study was to describe the behaviour of taurine in well-nourished (WN) rats and to analyse the influence of protein-energy undernutrition on the pharmacokinetic (PK) parameters of taurine, using a PK model. Read More

    SERUM ELECTROLYTES AND OUTCOME IN PATIENTS UNDERGOING ENDOSCOPIC GASTROSTOMY.
    Arq Gastroenterol 2018 Jan-Mar;55(1):41-45
    Departamento de Gastroenterologia, GENE - Artificial Feeding Team, Hospital Garcia de Orta, Almada, Portugal.
    Background: Percutaneous endoscopic gastrostomy (PEG) is a gold standard for long term enteral feeding. Neurologic dysphagia and head/neck cancer are the most common indications for PEG as they can lead to protein-energy malnutrition and serum electrolyte abnormalities, with potential negative impact on metabolic balance. Refeeding syndrome may also be related with severe electrolyte changes in PEG-fed patients and contribute to poor prognosis. Read More

    Partnering with families to promote nutrition in cancer care: feasibility and acceptability of the PIcNIC intervention.
    BMC Palliat Care 2018 Mar 20;17(1):50. Epub 2018 Mar 20.
    National Centre of Research Excellence in Nursing, Menzies Health Institute Queensland, Griffith University, Gold Cost, Australia.
    Background: Malnutrition is frequent in patients with cancer, particularly those in advanced stages of the disease. The aim of the present study was to test the feasibility of a family-centred nutritional intervention, based on the Family Systems theory and past research.

    Methods: This was a single-arm trial assessing feasibility (eligibility, recruitment and retention rates); acceptability by patients, family caregivers and health professionals; intervention fidelity, and energy/protein intake (in one site only). Read More

    Optima Nutrition: an allocative efficiency tool to reduce childhood stunting by better targeting of nutrition-related interventions.
    BMC Public Health 2018 Mar 20;18(1):384. Epub 2018 Mar 20.
    Burnet Institute, Melbourne, Australia.
    Background: Child stunting due to chronic malnutrition is a major problem in low- and middle-income countries due, in part, to inadequate nutrition-related practices and insufficient access to services. Limited budgets for nutritional interventions mean that available resources must be targeted in the most cost-effective manner to have the greatest impact. Quantitative tools can help guide budget allocation decisions. Read More

    Ready-to-use food supplement, with or without arginine and citrulline, with daily chloroquine in Tanzanian children with sickle-cell disease: a double-blind, random order crossover trial.
    Lancet Haematol 2018 Apr 13;5(4):e147-e160. Epub 2018 Mar 13.
    Developmental Neurosciences Programme, UCL Great Ormond Street Institute of Child Health, London, UK; Clinical and Experimental Sciences Unit, Faculty of Medicine, University of Southampton, Southampton, UK; University Child Health, University Hospital Southampton, Southampton, UK.
    Background: Sickle-cell disease increases the risk of malnutrition. Low arginine and nitric oxide bioavailability are implicated in morbidity related to sickle-cell disease. Simple interventions are required, especially in low-income settings. Read More

    Prospective associations of poor diet quality with long-term incidence of protein-energy malnutrition in community-dwelling older adults: the Health, Aging, and Body Composition (Health ABC) Study.
    Am J Clin Nutr 2018 Feb;107(2):155-164
    Department of Health Sciences, Faculty of Earth and Life Sciences, Amsterdam Public Health Research Institute, Vrije Universiteit, Amsterdam, Netherlands.
    Background: Protein-energy malnutrition (PEM) is a major problem in older adults. Whether poor diet quality is an indicator for the long-term development of PEM is unknown.

    Objective: The aim was to determine whether poor diet quality is associated with the incidence of PEM in community-dwelling older adults. Read More

    Maternal green tea polyphenol intake during lactation attenuates kidney injury in high-fat-diet-fed male offspring programmed by maternal protein restriction in rats.
    J Nutr Biochem 2018 Feb 9;56:99-108. Epub 2018 Feb 9.
    Aomori University of Health and Welfare, Graduate School of Health Sciences, Aomori, Japan; Department of Nutrition, Aomori University of Health and Welfare, Aomori, Japan. Electronic address:
    Maternal malnutrition is known to increase the risk of obesity in offspring. We investigated whether green tea extract (GTE) intake during lactation affects obesity-related fibrosis and inflammation in the kidney of high-fat-diet-fed adult offspring of protein-restricted-diet-fed dams during pregnancy and lactation. Pregnant Wistar rats received diets containing 20% (normal-protein, NP) or 8% (low-protein, LP) casein, and they received 0%-, 0. Read More

    Association of energy and protein intakes with length of stay, readmission and mortality in hospitalised patients with chronic obstructive pulmonary disease.
    Br J Nutr 2018 Mar;119(5):543-551
    1Unit for Nutrition Research,Landspitali University Hospital& Faculty of Food Science and Nutrition,University of Iceland,101 Reykjavik,Iceland.
    Low energy and protein intakes have been associated with an increased risk of malnutrition in outpatients with chronic obstructive pulmonary disease (COPD). We aimed to assess the energy and protein intakes of hospitalised COPD patients according to nutritional risk status and requirements, and the relative contribution from meals, snacks, drinks and oral nutritional supplements (ONS), and to examine whether either energy or protein intake predicts outcomes. Subjects were COPD patients (n 99) admitted to Landspitali University Hospital in 1 year (March 2015-March 2016). Read More

    [Effect of postoperative precision nutrition therapy on postoperative recovery for advanced gastric cancer after neoadjuvant chemotherapy].
    Zhonghua Zhong Liu Za Zhi 2018 Feb;40(2):127-132
    The Third Department of Surgery, the Fourth Affiliated Hospital, Hebei Medical University, Shijiazhuang 050011, China.
    To investigate the effect of postoperative precision nutrition therapy on postoperative recovery (PR) of patients with advanced gastric cancer (AGC) after neoadjuvant chemotherapy (NC). 71 subjects were randomly divided into 2 groups. The 34 patients of research group were treated with postoperative precision nutrition treatment according to the indirect energy measurement method. Read More

    Effect of mixed maize-legume silages on milk quality and quantity from lactating smallholder dairy cows.
    Trop Anim Health Prod 2018 Mar 3. Epub 2018 Mar 3.
    Department of Crop Science, University of Zimbabwe, Harare, Zimbabwe.
    The study investigated the effect of the following maize:legume (70:30) mixed crop silages: maize:cowpea, maize:velvet bean, and maize:lablab on milk production during the 2016 dry season. Using a 5 × 5 double Latin square design, five Holstein-Friesian crossbred cows in early lactation (30 ± 15 days) and five Jersey crossbred cows in early lactation (25 ± 10 days) were given the supplementary mixed crop silage diets at 0.5 kg/l of milk produced over 105 days. Read More

    [Malnutrition: from pathogenesis to current methods for diagnosis and treatment].
    Ter Arkh 2017 ;89(12. Vyp. 2):216-225
    N.I. Pirogov Russian National Research Medical University, Ministry of Health of Russia, Moscow, Russia.
    Progressive weight loss is a frequent companion to somatic pathology. The risk of death is known to increase dramatically among those with a body mass index of less than 19 kg/m. Even mild weight loss in the presence of severe diseases can have a substantial impact on the course of the disease. Read More

    Prevalence of obesity and diabetes in the socioeconomic transition of rural Mayas of Yucatan from 1962 to 2000.
    Ethn Health 2018 Feb 20:1-7. Epub 2018 Feb 20.
    e Facultad de Medicina , Universidad Autónoma de Yucatán , Mérida , México . Yucatán PAA: mi tendencia a indicar primero la obesidad tiene raices en la fisiopatología de estas enfermedades, ya que la obesidad suele preceder el desarrollo de la diabetes del adulto.
    Background: The Mayas of the State of Yucatan in Mexico are the only aboriginal group with obesity and diabetes data before 1997.

    Objective: To analyze socioeconomic trends associated with the increase in obesity and diabetes seen in rural Yucatan from 1962 to 2000.

    Methods: Body weight, height and venous Fasting Blood Glucose (FBG) were measured in 263 rural Maya adults participating in a 2000 nutrition survey. Read More

    Association between Bone Mineral Density of Femoral Neck and Geriatric Nutritional Risk Index in Rheumatoid Arthritis Patients Treated with Biological Disease-Modifying Anti-Rheumatic Drugs.
    Nutrients 2018 Feb 18;10(2). Epub 2018 Feb 18.
    The Near-Future Locomotor Organ Medicine Creation Course (Kusunoki Kai), Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima 890-8520, Japan.
    Treatment of rheumatoid arthritis (RA) with biological disease-modifying anti-rheumatic drugs (bDMARDs) induces rapid remission. However, osteoporosis and its management remains a problem. The Geriatric Nutritional Risk Index (GNRI) evaluates the risk of malnutrition-related complications in elderly patients and has been shown to be a significant predictor of many diseases. Read More

    Improved nutrition for extremely preterm infants - A population based observational study.
    Clin Nutr ESPEN 2018 Feb 10;23:245-251. Epub 2017 Oct 10.
    Department of Food and Nutrition, Umeå University, Umeå, Sweden.
    Background And Aims: Extremely preterm (EPT) infants are at high risk for malnutrition due to immaturity and medical complications and they often accumulate nutritional deficits and experience growth faltering during treatment at neonatal intensive care units (NICUs). Enhanced intake of energy and protein during the first weeks of life improves weight gain and head circumference growth. The optimal nutritional strategy for these infants' health and long-term development remains unknown. Read More

    Customized nutrition intervention and personalized counseling helps achieve nutrition targets in perioperative liver transplant patients.
    Clin Nutr ESPEN 2018 Feb 26;23:200-204. Epub 2017 Oct 26.
    Department of Liver Transplantation, Apollo Hospitals, Chennai, India.
    Background And Aim: Nutritional therapy is an integral part of care in all phases of liver transplantation (LTx). However, there are several factors that make it a challenge to manage malnutrition in these patients including, but not limited to, loss of appetite, dietary restrictions and dietary habits. Dietary habits are guided by personal choice, social, cultural and regional background with diversity ranging from veganism to vegetarianism with the latter predominant in Indian population. Read More

    N-terminal-pro-B-type-natriuretic peptide associated with 2-year mortality from both cardiovascular and non-cardiovascular origins in prevalent chronic hemodialysis patients.
    Ren Fail 2018 Nov;40(1):127-134
    b Department of Hemovascular Medicine and Artificial Organs, Faculty of Medicine , University of Miyazaki , Miyazaki , Japan.
    N-terminal-pro-B-type-natriuretic peptide (NT-proBNP) was a predictive marker of cardiovascular disease (CVD)-related death in chronic dialysis patients. NT-proBNP was also correlated with markers of inflammation, malnutrition and protein-energy wasting. We hypothesized whether NT-proBNP was also associated with non-CVD death in chronic dialysis patients. Read More

    Global disability-adjusted life-year estimates of long-term health burden and undernutrition attributable to diarrhoeal diseases in children younger than 5 years.
    Lancet Glob Health 2018 Mar;6(3):e255-e269
    Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA. Electronic address:
    Background: Diarrhoea is a leading cause of death and illness globally among children younger than 5 years. Mortality and short-term morbidity cause substantial burden of disease but probably underestimate the true effect of diarrhoea on population health. This underestimation is because diarrhoeal diseases can negatively affect early childhood growth, probably through enteric dysfunction and impaired uptake of macronutrients and micronutrients. Read More

    Are patients affected by mitochondrial disorders at nutritional risk?
    Nutrition 2018 Mar 12;47:56-62. Epub 2017 Oct 12.
    Division of Diabetes, Endocrinology, Nutritional Medicine and Metabolism, Bern University Hospital and University of Bern, Switzerland.
    Objectives: Patients with mitochondrial disorders (MD) frequently present with gastrointestinal complaints, mainly gastrointestinal dysmotility, that interfere with their food intake. A deterioration of their nutritional state may worsen the course of the disease. Our study aimed to evaluate a simple screening tool to identify nutritional risk and perform an extended nutritional assessment to explore the potential presence of deficiencies in this population compared with controls. Read More

    The relationship between nutritional status and handgrip strength in adult cancer patients: a cross-sectional study.
    Support Care Cancer 2018 Feb 9. Epub 2018 Feb 9.
    Faculty of Health Sciences, Department of Nutrition and Dietetics, Hacettepe University, 06100, Ankara, Turkey.
    Purpose: Malnutrition is a common complication in head, neck and lung cancer patients, particularly in cases of gastrointestinal system (GIS) cancer. Therefore, an assessment of malnutrition is crucial for early nutritional interventions. It was conducted as a cross-sectional study to evaluate nutritional status of adult cancer patients. Read More

    Dietetic intervention for inpatients on fluid-only diets helps to achieve nutritional requirements.
    Nutr Diet 2018 Feb 14;75(1):17-23. Epub 2017 Jun 14.
    Allied Health Management Unit, The Townsville Hospital, Townsville Hospital and Health Service, Townsville, Queensland, Australia.
    Aim: The present study aimed to assess whether dietetic intervention helps patients on fluid-only diets to meet their energy and protein requirements. This topic has not been previously investigated.

    Methods: A quasi-experimental study of 57 patients receiving fluid-only diets was conducted at The Townsville Hospital. Read More

    Fasciolopsiasis in children: Clinical, sociodemographic profile and outcome.
    Indian J Med Microbiol 2017 Oct-Dec;35(4):551-554
    Department of Community Medicine, Government Medical College, Bettiah, Bihar, India.
    Purpose: To describe the clinical and sociodemographic profile of fasciolopsiasis in children.

    Materials And Methods: A chart review of 56 children presenting with the passage of adult Fasciolopsis buski per stool from February 2015 to January 2016 was done for their clinical profile and risk factors for acquiring fasciolopsiasis in the Paediatric Unit of a medical college of Northern India.

    Results: The mean age of presentation was 8. Read More

    A multi-center survey on dietary knowledge and behavior among inpatients in oncology department.
    Support Care Cancer 2018 Feb 5. Epub 2018 Feb 5.
    Oncology Department, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China.
    Objective: To investigate the current associated factors of dietary knowledge and behavior, the intake and nutritional status in malignancy Chinese inpatients, and the malnutrition causes involved in dietary nutrition knowledge level and behavior, providing recommendations to patients for nutrition education and intervention.

    Method: Five hundred and thirty-five participants from 18 hospitals were investigated by a questionnaire related to dietary knowledge and behavior. Physicians asked and recorded the level of dietary intake and appetite scoring of the participants. Read More

    Effect of the 2015 earthquake on pediatric inpatient pattern at a tertiary care hospital in Nepal.
    BMC Pediatr 2018 02 5;18(1):28. Epub 2018 Feb 5.
    American International Medical University, Gros Islet, Saint Lucia.
    Background: Earthquakes impact child health in many ways. Diseases occurring immediately following an earthquake have been studied in field based hospitals but studies on the inpatient disease pattern among children without trauma in a permanent hospital setup is lacking.

    Methods: We examined the diagnoses of all children without trauma, admitted to Kanti Children's Hospital, Kathmandu for fifteen-week duration (from 4th week to end of the 18th week) following the 7. Read More

    Protein-Energy Malnutrition Exacerbates Stroke-Induced Forelimb Abnormalities and Dampens Neuroinflammation.
    Transl Stroke Res 2018 Feb 3. Epub 2018 Feb 3.
    College of Pharmacy and Nutrition, University of Saskatchewan, D Wing Health Sciences, 107 Wiggins Road, Saskatoon, SK, S7N 5E5, Canada.
    Protein-energy malnutrition (PEM) pre-existing at stroke onset is believed to worsen functional outcome, yet the underlying mechanisms are not fully understood. Since brain inflammation is an important modulator of neurological recovery after stroke, we explored the impact of PEM on neuroinflammation in the acute period in relation to stroke-initiated sensori-motor abnormalities. Adult rats were fed a low-protein (LP) or normal protein (NP) diet for 28 days before inducing photothrombotic stroke (St) in the forelimb region of the motor cortex or sham surgery; the diets continued for 3 days after the stroke. Read More

    Contributors to nutritional status in continuous ambulatory peritoneal dialysis as practised in Henan Province, China.
    Asia Pac J Clin Nutr 2018 ;27(2):318-321
    Kidney Internal Medicine Department, the First Affiliated Hospital of Zhengzhou University, Zhengzhou City, Henan province, China. Email:
    Background And Objectives: To investigate the nutritional status of patients undergoing continuous ambulatory peritoneal dialysis (CAPD) and the factors involved.

    Methods And Study Design: We used the Subjective Global Assessment (SGA) of nutritional status, a general questionnaire, dietary records, and laboratory parameters from 3 consecutive days to develop a NS assessment with it, we assessed 240 patients undergoing CAPD at a dialysis center in Henan Province.

    Results: In this setting, the prevalence of malnutrition in patients undergoing CAPD was 11. Read More

    Fructose Feeding during the Postabsorptive State Alters Body Composition and Spares Nitrogen in Protein-Energy-Restricted Old Rats.
    J Nutr 2018 Jan;148(1):40-48
    Université Clermont Auvergne, INRA, UNH, Unité de Nutrition Humaine, CRNH Auvergne, Clermont-Ferrand, France.
    Background: Fructose feeding in the context of high energy intake is recognized as being responsible for metabolic dysregulation. However, its consumption in the postabsorptive state might contribute to reducing the use of amino acids (AAs) as energy substrates and thus spare nitrogen resources, which could be beneficial during catabolic states.

    Objective: We hypothesized that fructose feeding during a catabolic situation corresponding to protein-energy restriction (PER) in older rats would reduce AA utilization for energy purposes, thus slowing down the loss of body weight (BW) and improving body composition. Read More

    Age modifies the association between serum obestatin, appetite and nutritional status in maintenance hemodialysis patients.
    Eur J Clin Nutr 2018 Jan 23. Epub 2018 Jan 23.
    Nephrology Division, Assaf Harofeh Medical Center, Zerifin, Affiliated to Sackler Faculty of Medicine Tel Aviv University, Tel Aviv, Israel.
    Background/objectives: Increased age is strongly associated with anorexia and protein-energy wasting (PEW) in maintenance hemodialysis (MHD) population. We hypothesized that the association of obestatin, a recently discovered anorexigenic gut hormone, with appetite and nutritional status differs by age groups.

    Subjects/methods: We performed a cross-sectional study on 261MHD patients. Read More

    Effects of Substitution, and Adding of Carbohydrate and Fat to Whey-Protein on Energy Intake, Appetite, Gastric Emptying, Glucose, Insulin, Ghrelin, CCK and GLP-1 in Healthy Older Men-A Randomized Controlled Trial.
    Nutrients 2018 Jan 23;10(2). Epub 2018 Jan 23.
    Discipline of Medicine and National Health and Medical Research Council of Australia (NHMRC) Centre of Research Excellence in Translating Nutritional Science to Good Health, Adelaide Medical School, Adelaide, SA 5000, Australia.
    Protein-rich supplements are used widely for the management of malnutrition in the elderly. We reported previously that the suppression of energy intake by whey protein is less in older than younger adults. The aim was to determine the effects of substitution, and adding of carbohydrate and fat to whey protein, on ad libitum energy intake from a buffet meal (180-210 min), gastric emptying (3D-ultrasonography), plasma gut hormone concentrations (0-180 min) and appetite (visual analogue scales), in healthy older men. Read More

    Longitudinal Profiles of Metabolism and Bioenergetics Associated with Innate Immune Hormonal Inflammatory Responses and Amino-Acid Kinetics in Severe Sepsis and Systemic Inflammatory Response Syndrome in Children.
    JPEN J Parenter Enteral Nutr 2018 Jan 16. Epub 2018 Jan 16.
    Pediatric Intensive Care Unit, University Hospital, Medical School, University of Crete, Heraklion, Greece.
    Background: Experimental data indicate that sepsis influences the mitochondrial function and metabolism. We aim to investigate longitudinal bioenergetic, metabolic, hormonal, amino-acid, and innate immunity changes in children with sepsis.

    Methods: Sixty-eight children (sepsis, 18; systemic inflammatory response syndrome [SIRS], 23; healthy controls, 27) were enrolled. Read More

    Relationship between growth and illness, enteropathogens and dietary intakes in the first 2 years of life: findings from the MAL-ED birth cohort study.
    • Authors:
    BMJ Glob Health 2017 28;2(4):e000370. Epub 2017 Dec 28.
    Background: Dietary and illness factors affect risk of growth faltering; the role of enteropathogens is less clear. As part of the Etiology, Risk Factors and Interactions of Enteric Infections and Malnutrition and the Consequences for Child Health and Development (MAL-ED) study, we quantify the effects of enteropathogen infection, diarrhoea and diet on child growth.

    Methods: Newborns were enrolled and followed until 24 months. Read More

    Nutritional deficiency during colonoscopy preparation: the forgotten iatrogeny.
    Rev Esp Enferm Dig 2018 Jan 15;110. Epub 2018 Jan 15.
    Gastroenterology, Hospital Garcia de Orta.
    Background And Aims: Bowel preparation for colonoscopy induces a semi-fasting state, with a potential negative impact on fragile patients. The present study aims to quantify nutritional deficiency during colonoscopy preparation.

    Methods: This was an observational and cross-sectional study. Read More

    Dose-Dependent Effects of Randomized Intraduodenal Whey-Protein Loads on Glucose, Gut Hormone, and Amino Acid Concentrations in Healthy Older and Younger Men.
    Nutrients 2018 Jan 12;10(1). Epub 2018 Jan 12.
    Discipline of Medicine and National Health and Medical Research Council of Australia (NHMRC) Centre of Research Excellence in Translating Nutritional Science to Good Health, Adelaide Medical School, Adelaide 5000, Australia.
    Protein-rich supplements are used widely for the prevention and management of malnutrition in older people. We have reported that healthy older, compared to younger, adults have less suppression of energy intake by whey-protein-effects on appetite-related hormones are unknown. The objective was to determine the effects of intraduodenally administered whey-protein on glucose, gut hormone, and amino acid concentrations, and their relation to subsequent energy intake at a buffet meal, in healthy older and younger men. Read More

    The Prediction of Deterioration of Nutritional Status during Chemoradiation Therapy in Patients with Esophageal Cancer.
    Nutr Cancer 2018 Feb-Mar;70(2):229-235. Epub 2018 Jan 11.
    a Department of Nutrition and Dietetics , Internal Medicine, VU University Medical Center , Amsterdam , The Netherlands.
    Patients with esophageal cancer are at high risk of developing malnutrition during neoadjuvant chemoradiation therapy (CRT), which in turn is associated with postoperative morbidity. The aim of the study is to explore whether parameters of a complete pre-treatment nutritional status may predict deterioration of nutritional status during CRT in patients with esophageal cancer. In this prospective cohort study, 101 patients with esophageal cancer treated with CRT were included. Read More

    Can fortified foods and snacks increase the energy and protein intake of hospitalised older patients? A systematic review.
    J Hum Nutr Diet 2018 Jan 10. Epub 2018 Jan 10.
    Academic Geriatric Medicine, University of Southampton, Southampton General Hospital Mailpoint, Southampton, UK.
    Background: Undernutrition affects over 44% of hospitalised older people, who often dislike oral nutritional supplements (ONS). This review summarises the evidence for an alternative strategy, using energy and protein dense meals (via fortification) or snacks (supplementation) to increase the dietary energy and protein intake of older inpatients.

    Methods: A search was conducted through PubMed, EMBASE, CINAHL and the Cochrane database of systematic reviews (May 1996 to May 2016) that used fortification or supplementation to increase the energy or protein intake of patients (mean age ≥60 years) in hospitals or rehabilitation centres. Read More

    Dysphagia in Hospitalized Older Patients: Associated Factors and Nutritional Interventions.
    J Nutr Health Aging 2018 ;22(1):103-110
    Doris Eglseer, Research Assistant, Medical University of Graz, Institute of Nursing Science, Billrothgasse 6, 8010 Graz, Phone: +43/316/385-71635, E-Mail:
    Objectives: To (1) assess the association between dysphagia and malnutrition as well as other related factors and (2) investigate the nutritional interventions that are initiated in dysphagic older patients.

    Design: Cross-sectional, multi-center point prevalence measurement.

    Setting: 53 Austrian hospitals. Read More

    Diet, Microbiota, and Metabolic Health: Trade-Off Between Saccharolytic and Proteolytic Fermentation.
    Annu Rev Food Sci Technol 2018 Mar 3;9:65-84. Epub 2018 Jan 3.
    Department of Bacteriology and Immunology, Immunobiology Research Program, 00014 University of Helsinki, Finland; email:
    The intestinal microbiota have emerged as a central regulator of host metabolism and immune function, mediating the effects of diet on host health. However, the large diversity and individuality of the gut microbiota have made it difficult to draw conclusions about microbiota responses to dietary interventions. In the light of recent research, certain general patterns are emerging, revealing how the ecology of the gut microbiota profoundly depends on the quality and quantity of dietary carbohydrates and proteins. Read More

    Tailoring nutrition therapy to illness and recovery.
    Crit Care 2017 Dec 28;21(Suppl 3):316. Epub 2017 Dec 28.
    Department of Anesthesiology and Surgery, Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC, USA.
    Without doubt, in medicine as in life, one size does not fit all. We do not administer the same drug or dose to every patient at all times, so why then would we live under the illusion that we should give the same nutrition at all times in the continuum of critical illness? We have long lived under the assumption that critical illness and trauma lead to a consistent early increase in metabolic/caloric need, the so-called "hypermetabolism" of critical illness. What if this is incorrect? Recent data indicate that early underfeeding of calories (trophic feeding) may have benefits and may require consideration in well-nourished patients. Read More

    Food intake, plate waste and its association with malnutrition in hospitalized patients.
    Nutr Hosp 2017 Nov 16;34(5):1376-1381. Epub 2017 Nov 16.
    .
    Background: Hospital malnutrition is a worldwide dilemma and challenge. High levels of plate waste contribute to malnutrition-related complications in hospital. We investigated the association between the levels of plate waste, food intake and patient satisfaction with nutritional risk and malnutrition prevalence in three hospital settings. Read More

    Dietary intake and zinc status in amyotrophic lateral sclerosis patients.
    Nutr Hosp 2017 Oct 27;34(5):1361-1367. Epub 2017 Oct 27.
    Graduate Program in Nutrition Department of Nutrition, Federal University of Rio Grande do Norte.
    Background: There is considerable evidence that abnormal zinc homeostasis is related to amyotrophic lateral sclerosis (ALS) pathogenesis, and malnutrition is an independent prognostic factor for worsened survival of ALS patients.

    Objective: To evaluate the dietary intake and zinc status in patients with ALS, treated in a specialized outpatient facility in Natal, Brazil.

    Methods: Twenty patients with ALS (case group) and 37 healthy subjects (control group) were included. Read More

    Texture-modified diets are associated with decreased muscle mass in older adults admitted to a rehabilitation ward.
    Geriatr Gerontol Int 2017 Dec 26. Epub 2017 Dec 26.
    Department of Health Sciences, Faculty of Human Culture and Science, Prefectural University of Hiroshima, Hiroshima, Japan.
    Aim: Texture-modified diets (TMD) have significantly lower energy and protein content than normal diets. Therefore, TMD can cause malnutrition and loss of muscle mass. However, few studies have reported the relationship between TMD and decreased skeletal muscle mass. Read More

    Ready-to-Use Therapeutic Food Made From Locally Available Food Ingredients Is Well Accepted by Children Having Severe Acute Malnutrition in Bangladesh.
    Food Nutr Bull 2018 Mar 19;39(1):116-126. Epub 2017 Dec 19.
    1 International Centre for Diarrhoeal Disease Research, Bangladesh, Mohakhali, Dhaka, Bangladesh.
    Background: With a prevalence of 3.1%, approximately, 450 000 children in Bangladesh are having severe acute malnutrition (SAM). There is currently no national community-based program run by government to take care of these children, one of the reasons being lack of access to ready-to-use therapeutic food (RUTF). Read More

    Rural protein insufficiency in a wildlife-depleted West African farm-forest landscape.
    PLoS One 2017 13;12(12):e0188109. Epub 2017 Dec 13.
    Zoological Society of London, Institute of Zoology, London, United Kingdom.
    Introduction: Wildlife is an important source of protein for many people in developing countries. Yet wildlife depletion due to overexploitation is common throughout the humid tropics and its effect on protein security, especially for vulnerable households, is poorly understood. This is problematic for both sustainable rural development and conservation management. Read More

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