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    1 OF 191

    Longitudinal Profiles of Metabolism and Bioenergetics Associated with Innate Immune Hormonal Inflammatory Responses and Amino-Acid Kinetics in Severe Sepsis and Systemic Inflammatory Response Syndrome in Children.
    JPEN J Parenter Enteral Nutr 2018 Jan 16. Epub 2018 Jan 16.
    Pediatric Intensive Care Unit, University Hospital, Medical School, University of Crete, Heraklion, Greece.
    Background: Experimental data indicate that sepsis influences the mitochondrial function and metabolism. We aim to investigate longitudinal bioenergetic, metabolic, hormonal, amino-acid, and innate immunity changes in children with sepsis.

    Methods: Sixty-eight children (sepsis, 18; systemic inflammatory response syndrome [SIRS], 23; healthy controls, 27) were enrolled. Read More

    Relationship between growth and illness, enteropathogens and dietary intakes in the first 2 years of life: findings from the MAL-ED birth cohort study.
    • Authors:
    BMJ Glob Health 2017 28;2(4):e000370. Epub 2017 Dec 28.
    Background: Dietary and illness factors affect risk of growth faltering; the role of enteropathogens is less clear. As part of the Etiology, Risk Factors and Interactions of Enteric Infections and Malnutrition and the Consequences for Child Health and Development (MAL-ED) study, we quantify the effects of enteropathogen infection, diarrhoea and diet on child growth.

    Methods: Newborns were enrolled and followed until 24 months. Read More

    Nutritional deficiency during colonoscopy preparation: the forgotten iatrogeny.
    Rev Esp Enferm Dig 2018 Jan 15;110. Epub 2018 Jan 15.
    Gastroenterology, Hospital Garcia de Orta.
    Background And Aims: Bowel preparation for colonoscopy induces a semi-fasting state, with a potential negative impact on fragile patients. The present study aims to quantify nutritional deficiency during colonoscopy preparation.

    Methods: This was an observational and cross-sectional study. Read More

    Dose-Dependent Effects of Randomized Intraduodenal Whey-Protein Loads on Glucose, Gut Hormone, and Amino Acid Concentrations in Healthy Older and Younger Men.
    Nutrients 2018 Jan 12;10(1). Epub 2018 Jan 12.
    Discipline of Medicine and National Health and Medical Research Council of Australia (NHMRC) Centre of Research Excellence in Translating Nutritional Science to Good Health, Adelaide Medical School, Adelaide 5000, Australia.
    Protein-rich supplements are used widely for the prevention and management of malnutrition in older people. We have reported that healthy older, compared to younger, adults have less suppression of energy intake by whey-protein-effects on appetite-related hormones are unknown. The objective was to determine the effects of intraduodenally administered whey-protein on glucose, gut hormone, and amino acid concentrations, and their relation to subsequent ad libitum energy intake at a buffet meal, in healthy older and younger men. Read More

    The Prediction of Deterioration of Nutritional Status during Chemoradiation Therapy in Patients with Esophageal Cancer.
    Nutr Cancer 2018 Jan 11:1-7. Epub 2018 Jan 11.
    a Department of Nutrition and Dietetics , Internal Medicine, VU University Medical Center , Amsterdam , The Netherlands.
    Patients with esophageal cancer are at high risk of developing malnutrition during neoadjuvant chemoradiation therapy (CRT), which in turn is associated with postoperative morbidity. The aim of the study is to explore whether parameters of a complete pre-treatment nutritional status may predict deterioration of nutritional status during CRT in patients with esophageal cancer. In this prospective cohort study, 101 patients with esophageal cancer treated with CRT were included. Read More

    Can fortified foods and snacks increase the energy and protein intake of hospitalised older patients? A systematic review.
    J Hum Nutr Diet 2018 Jan 10. Epub 2018 Jan 10.
    Academic Geriatric Medicine, University of Southampton, Southampton General Hospital Mailpoint, Southampton, UK.
    Background: Undernutrition affects over 44% of hospitalised older people, who often dislike oral nutritional supplements (ONS). This review summarises the evidence for an alternative strategy, using energy and protein dense meals (via fortification) or snacks (supplementation) to increase the dietary energy and protein intake of older inpatients.

    Methods: A search was conducted through PubMed, EMBASE, CINAHL and the Cochrane database of systematic reviews (May 1996 to May 2016) that used fortification or supplementation to increase the energy or protein intake of patients (mean age ≥60 years) in hospitals or rehabilitation centres. Read More

    Dysphagia in Hospitalized Older Patients: Associated Factors and Nutritional Interventions.
    J Nutr Health Aging 2018 ;22(1):103-110
    Doris Eglseer, Research Assistant, Medical University of Graz, Institute of Nursing Science, Billrothgasse 6, 8010 Graz, Phone: +43/316/385-71635, E-Mail:
    Objectives: To (1) assess the association between dysphagia and malnutrition as well as other related factors and (2) investigate the nutritional interventions that are initiated in dysphagic older patients.

    Design: Cross-sectional, multi-center point prevalence measurement.

    Setting: 53 Austrian hospitals. Read More

    Tailoring nutrition therapy to illness and recovery.
    Crit Care 2017 Dec 28;21(Suppl 3):316. Epub 2017 Dec 28.
    Department of Anesthesiology and Surgery, Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC, USA.
    Without doubt, in medicine as in life, one size does not fit all. We do not administer the same drug or dose to every patient at all times, so why then would we live under the illusion that we should give the same nutrition at all times in the continuum of critical illness? We have long lived under the assumption that critical illness and trauma lead to a consistent early increase in metabolic/caloric need, the so-called "hypermetabolism" of critical illness. What if this is incorrect? Recent data indicate that early underfeeding of calories (trophic feeding) may have benefits and may require consideration in well-nourished patients. Read More

    Food intake, plate waste and its association with malnutrition in hospitalized patients.
    Nutr Hosp 2017 Nov 16;34(5):1376-1381. Epub 2017 Nov 16.
    .
    Background: Hospital malnutrition is a worldwide dilemma and challenge. High levels of plate waste contribute to malnutrition-related complications in hospital. We investigated the association between the levels of plate waste, food intake and patient satisfaction with nutritional risk and malnutrition prevalence in three hospital settings. Read More

    Dietary intake and zinc status in amyotrophic lateral sclerosis patients.
    Nutr Hosp 2017 Oct 27;34(5):1361-1367. Epub 2017 Oct 27.
    Graduate Program in Nutrition Department of Nutrition, Federal University of Rio Grande do Norte.
    Background: There is considerable evidence that abnormal zinc homeostasis is related to amyotrophic lateral sclerosis (ALS) pathogenesis, and malnutrition is an independent prognostic factor for worsened survival of ALS patients.

    Objective: To evaluate the dietary intake and zinc status in patients with ALS, treated in a specialized outpatient facility in Natal, Brazil.

    Methods: Twenty patients with ALS (case group) and 37 healthy subjects (control group) were included. Read More

    Texture-modified diets are associated with decreased muscle mass in older adults admitted to a rehabilitation ward.
    Geriatr Gerontol Int 2017 Dec 26. Epub 2017 Dec 26.
    Department of Health Sciences, Faculty of Human Culture and Science, Prefectural University of Hiroshima, Hiroshima, Japan.
    Aim: Texture-modified diets (TMD) have significantly lower energy and protein content than normal diets. Therefore, TMD can cause malnutrition and loss of muscle mass. However, few studies have reported the relationship between TMD and decreased skeletal muscle mass. Read More

    Ready-to-Use Therapeutic Food Made From Locally Available Food Ingredients Is Well Accepted by Children Having Severe Acute Malnutrition in Bangladesh.
    Food Nutr Bull 2017 Jan 1:379572117743929. Epub 2017 Jan 1.
    1 International Centre for Diarrhoeal Disease Research, Bangladesh, Mohakhali, Dhaka, Bangladesh.
    Background: With a prevalence of 3.1%, approximately, 450 000 children in Bangladesh are having severe acute malnutrition (SAM). There is currently no national community-based program run by government to take care of these children, one of the reasons being lack of access to ready-to-use therapeutic food (RUTF). Read More

    Rural protein insufficiency in a wildlife-depleted West African farm-forest landscape.
    PLoS One 2017 13;12(12):e0188109. Epub 2017 Dec 13.
    Zoological Society of London, Institute of Zoology, London, United Kingdom.
    Introduction: Wildlife is an important source of protein for many people in developing countries. Yet wildlife depletion due to overexploitation is common throughout the humid tropics and its effect on protein security, especially for vulnerable households, is poorly understood. This is problematic for both sustainable rural development and conservation management. Read More

    Nutrition and Muscle in Cirrhosis.
    J Clin Exp Hepatol 2017 Dec 8;7(4):340-357. Epub 2017 Nov 8.
    Indraprastha Apollo Hospital, New Delhi, India.
    As the cirrhosis progresses, development of complication like ascites, hepatic encephalopathy, variceal bleeding, kidney dysfunction, and hepatocellular carcinoma signify increasing risk of short term mortality. Malnutrition and muscle wasting (sarcopenia) is yet other complications that negatively impact survival, quality of life, and response to stressors, such as infection and surgery in patients with cirrhosis. Conventionally, these are not routinely looked for, because nutritional assessment can be a difficult especially if there is associated fluid retention and/or obesity. Read More

    Effectiveness of nutritional interventions addressed to elderly persons: umbrella systematic review with meta-analysis.
    Eur J Public Health 2017 Dec 8. Epub 2017 Dec 8.
    Department of Hygiene, Institute of Public Health, Università Cattolica del Sacro Cuore, Rome, Italy.
    Background: The number of Europeans aged over 65 will double between 2010 and 2060, reaching 30% of the European population. Nutrition is emerging as a key element of healthy life since both obesity and malnutrition are established risk factors for morbidity and disability. The aim of this umbrella review (UR) is to summarize the findings of all current systematic reviews (SRs) and meta-analyzes (MAs) on the effectiveness of nutritional intervention designed to promote healthy aging in older individuals. Read More

    Optimization of perioperative management of proximal femoral fracture in the elderly.
    Orthop Traumatol Surg Res 2017 Dec 1. Epub 2017 Dec 1.
    Clinique Universitaire d'Orthopédie-Traumatologie, CHU Albert Michallon, Grenoble, France. Electronic address:
    Proximal femoral fracture in elderly subjects is a major event that is life-threatening in the medium-to-long term. Advanced age, male gender and number of comorbidities largely account for high mortality and require geriatric expertise. Protein-energy malnutrition and bone demineralization increase mortality. Read More

    Nutritional status and management of risks due to physical therapy in patients hospitalized for long periods.
    J Phys Ther Sci 2017 Nov 24;29(11):1910-1913. Epub 2017 Nov 24.
    Department of Community Health Care Medicine, Hyogo College of Medicine, Japan.
    [Purpose] This study aimed to understand the nutritional status of patients hospitalized for long periods and the risk of physical therapy (PT) for such patients. [Subjects and Methods] Participants were selected from patients who were hospitalized at a designated medical long-term care sanatorium. The participants were divided into 5 groups (A-E) depending on their mode of energy intake and ambulatory ability during PT. Read More

    Association of Insulin-like Growth Factor-1, Bone Mass and Inflammation to Low-energy Distal Radius Fractures and Fracture Healing in Elderly Women Attending Emergency Care.
    Orthop Surg 2017 Nov;9(4):380-385
    Department of Endocrinology and Department of Medicine and Health Sciences, Linköping University, Linköping, Sweden.
    Objective: Elderly patients suffer fractures through low-energy mechanisms. The distal radius is the most frequent fracture localization. Insulin-like growth factor-1 (IGF1) plays an important role in the maintenance of bone mass and its levels decline with advancing age and in states of malnutrition. Read More

    An Even Distribution of Protein Intake Daily Promotes Protein Adequacy but Does Not Influence Nutritional Status in Institutionalized Elderly.
    J Am Med Dir Assoc 2018 Jan 22;19(1):33-39. Epub 2017 Nov 22.
    Department of Endocrinology/Medicine, University of Melbourne/Austin Health, West Heidelberg, Australia. Electronic address:
    Objective: Although it has been established that sufficient protein is required to maintain good nutritional status and support healthy aging, it is not clear if the pattern of protein consumption may also influence nutritional status, especially in institutionalized elderly who are at risk of malnutrition. Therefore, we aim to determine the association between protein intake distribution and nutritional status in institutionalized elderly people.

    Design: Cross-sectional study among 481 institutionalized older adults. Read More

    A novel in-hospital meal service improves protein and energy intake.
    Clin Nutr 2017 Nov 9. Epub 2017 Nov 9.
    Department of Gastroenterology and Hepatology, Radboudumc, Nijmegen, The Netherlands. Electronic address:
    Background & Aims: Improvement of hospital meal services is a strategy to optimize protein and energy intake and prevent or treat malnutrition during hospitalization. FoodforCare (FfC) is a new concept comprising 6-protein-rich meals per day, provided directly at the bedside following proactive advice from a nutritional assistant. Our aim is to investigate whether this new concept, FfC, improves dietary intake and patient satisfaction, compared to the traditional 3-meals a day service (TMS). Read More

    Exocrine pancreas glutamate secretion help to sustain enterocyte nutritional needs under protein restriction.
    Am J Physiol Gastrointest Liver Physiol 2017 Nov 22:ajpgi001352017. Epub 2017 Nov 22.
    1 University of Zurich.
    Glutamine (Gln) is the most concentrated amino acid in blood and considered conditionally essential. Its requirement is increased during physiological stress, such as malnutrition or illness, despite its production by muscle and other organs. In the malnourished state Gln has been suggested to have a trophic effect on the exocrine pancreas and small intestine. Read More

    Con: The role of diet for people with advanced Stage 5 CKD.
    Nephrol Dial Transplant 2017 Nov 17. Epub 2017 Nov 17.
    Renal Unit, St James's University Hospital, Leeds, UK.
    Restriction of dietary protein intake has been used in the management of chronic kidney disease (CKD) for many decades, yet remains controversial, with marked variations in its application in clinical practice. There is extensive literature on the subject, with some expert opinion advocating the use of protein restriction based on the balance of the available evidence. The largest randomized trial of low-protein diets is the Modification of Diet in Renal Disease study. Read More

    Nutritional screening and dietitian consultation rates in a geriatric evaluation and management unit.
    Nutr Diet 2017 Nov 22. Epub 2017 Nov 22.
    Centre for Research in Geriatric Medicine, Faculty of Medicine, The University of Queensland, Brisbane, Queensland, Australia.
    Aim: Nutritional screening may not always lead to intervention. The present study aimed to determine: (i) the rate of nutritional screening in hospitalised older adults; (ii) whether nutritional screening led to dietitian consultation and (iii) factors associated with malnutrition.

    Methods: In this prospective study of patients aged ≥70 years admitted to a Geriatric Evaluation and Management Unit (GEMU), malnutrition was screened for using the Mini Nutritional Assessment Short Form (MNA-SF) and identified using the Mini Nutritional Assessment (MNA). Read More

    Nutrition and immune system disorders
    Nutr Hosp 2017 10 15;34(Suppl 4):68-71. Epub 2017 Oct 15.
    .
    Introduction: Energy and nutrients obtained through food play an important role in the development and preservation of the immune system therefore any nutritional imbalance affects its competence and integrity.

    Objectives: Knowing the nutritional approach on different disorders of the immune system.

    Methods: A review has been carried out on the most prevalent immunological disorders in developed countries, the nutritional characteristics to which they are associated and their nutritional approach. Read More

    Predictors for achieving adequate protein and energy intake in nursing home rehabilitation patients.
    Aging Clin Exp Res 2017 Nov 17. Epub 2017 Nov 17.
    Dutch Malnutrition Steering Group, Nicolaas Witsenkade 13hs, 1017 ZR, Amsterdam, The Netherlands.
    Background: Adequate energy and protein intake could be essential for contributing significantly to the rehabilitations process. Data on the actual nutritional intake of older nursing home rehabilitation patients have not yet been investigated.

    Aims: To investigate the nutritional intake and predictors for achieving protein and energy requirements on the 14th day of admission in nursing home rehabilitation patients. Read More

    Nutrition Therapy in Sepsis.
    Crit Care Clin 2018 Jan 13;34(1):107-125. Epub 2017 Oct 13.
    Department of Anesthesiology, Duke University School of Medicine, 2400 Pratt Street, Office: NP 7060, Durham, NC 27705, USA. Electronic address:
    Sepsis is characterized by early massive catabolism, lean body mass (LBM) loss, and escalating hypermetabolism persisting for months to years. Early enteral nutrition should attempt to correct micronutrient/vitamin deficiencies, deliver adequate protein and moderated nonprotein calories, as well-nourished patients can generate reasonable endogenous energy. After resuscitation, increasing protein/calories are needed to attenuate LBM loss and promote recovery. Read More

    Defining, Recognizing, and Reporting Malnutrition.
    Int J Low Extrem Wounds 2017 Dec 16;16(4):230-237. Epub 2017 Nov 16.
    1 Faculty of Medicine, University of Southampton, Southampton, UK.
    Although malnutrition is a common health and social care problem, there is no universal agreement about its definition, prevalence, or method of identification and report. Fifteen definitions of malnutrition were critically examined to assess their variability. They ranged from descriptions of undernutrition alone to under- and overnutrition, with intakes ranging from dietary protein and energy alone to dietary and nondietary sources of all nutrients and energy. Read More

    Chronic Diarrhea in Common Variable Immunodeficiency: a Case Series and Review of the Literature.
    J Clin Immunol 2018 Jan 14;38(1):67-76. Epub 2017 Nov 14.
    Department of Translational Medical Sciences, Allergy and Clinical Immunology. Center for Basic and Clinical Immunology Research (CISI), University of Naples Federico II, Via S. Pansini 5, 80131, Naples, Italy.
    Common variable immunodeficiency (CVID) is a primary immunodeficiency characterized by reduced immunoglobulin serum levels and absent or impaired antibody production. Clinical manifestations, including infections, inflammatory and autoimmune diseases, and malignancies, also involve various segments of the gastrointestinal tract. Chronic diarrhea is one of the most common gastrointestinal symptoms and may cause a wide spectrum of potentially life-threatening conditions as malabsorption and protein-energy malnutrition. Read More

    A Cross-Sectional Study of Nutrient Intake and Health Status among Older Adults in Yogyakarta Indonesia.
    Nutrients 2017 Nov 13;9(11). Epub 2017 Nov 13.
    Discipline of Medicine and National Health and Medical Research Council (NHMRC), Centre of Research Excellence in Translating Nutritional Science to Good Health, The University of Adelaide, Adelaide, SA 5005, Australia.
    Many communities around the world, particularly developing countries including Indonesia, are experiencing population ageing. There is little knowledge regarding the impact of malnutrition, or its prevalence within rural compared to urban areas, on the nutritional, functional and mental status of community-living older residents in these countries. Hence, a cross-sectional study was conducted to determine socio-demographic and anthropometric characteristics, nutritional, mental and functional status, and energy and nutrient intake of community-dwelling Indonesians from both rural and urban areas of Yogyakarta. Read More

    Combined assessment of nutritional status in patients with peritoneal dialysis using bioelectrical impedance vectors and malnutrition inflammation score.
    Nutr Hosp 2017 Oct 24;34(5):1125-1132. Epub 2017 Oct 24.
    Universidad de Guanajuato.
    Background And Objective: Protein energy wasting (PEW) is a common syndrome in patients with chronic kidney disease, related to changes in hydration status, decreased food intake and inflammation. There are several tools for the assessment and diagnosis of such alterations. Bioimpedance vector analysis (BIVA) assess the state of nutrition and hydration, but not the inflammatory component, while the malnutrition inflammation score (MIS) comprises the inflammatory and nutritional factors, but not the state of hydration. Read More

    Effect of Personalized Nutritional Counseling on the Nutritional Status of Hemodialysis Patients.
    Clin Nutr Res 2017 Oct 30;6(4):285-295. Epub 2017 Oct 30.
    Department of Nutrition Care, Severance Hospital, Yonsei University College of Medicine, Seoul 03722, Korea.
    This study set out to evaluate the impact of personalized nutritional counseling (PNC) on the nutritional status of hemodialysis (HD) patients. This was an intervention study for 10 months at 2 hospitals. Anthropometric, biochemical, dietary, and body composition parameters were measured at baseline and after 3 and 6 months of PNC. Read More

    Nutrition strategies before and during ultra-endurance event: A significant gap between science and practice.
    Scand J Med Sci Sports 2017 Nov 8. Epub 2017 Nov 8.
    Department of Nutrition and Dietetics, Technological Institute of Thessaloniki, Thessaloniki, Greece.
    The purpose of this study was to investigate and assess the nutritional practices of open-water swimmers, during the preparation period and the competition, as well as their implications on performance and anthropometric parameters according to their age. Twenty-four (n = 24) men open-water swimmers, twelve young (26.3 ± 4. Read More

    Assessing the prevalence of protein-energy wasting in haemodialysis patients: A cross-sectional monocentric study.
    Nephrol Ther 2017 Dec 4;13(7):537-543. Epub 2017 Nov 4.
    Laboratory of biology and health, URAC 34, Hassan II university-Casablanca, faculty of sciences Ben M'Sik, avenue Cdt Driss El Harti, BP 7955, Sidi Othmane, Casablanca, Morocco. Electronic address:
    Introduction: Protein-energy wasting (PEW) is a strong predictive factor for morbidity and mortality in haemodialysis (HD) patients. However, there is no consensus for its assessment. The present study aimed to assess the nutritional status of patients on chronic HD by use of different nutritional assessment parameters, and at verifying which can identify the greatest number of HD patients with PEW. Read More

    A systematic review and meta-analysis of the criterion validity of nutrition assessment tools for diagnosing protein-energy malnutrition in the older community setting (the MACRo study).
    Clin Nutr 2017 Oct 12. Epub 2017 Oct 12.
    Faculty of Health Sciences and Medicine, Bond University, Robina, Queensland, 4226, Australia. Electronic address:
    Background & Aims: Malnutrition is a significant barrier to healthy and independent ageing in older adults who live in their own homes, and accurate diagnosis is a key step in managing the condition. However, there has not been sufficient systematic review or pooling of existing data regarding malnutrition diagnosis in the geriatric community setting. The current paper was conducted as part of the MACRo (Malnutrition in the Ageing Community Review) Study and seeks to determine the criterion (concurrent and predictive) validity and reliability of nutrition assessment tools in making a diagnosis of protein-energy malnutrition in the general older adult community. Read More

    Low-protein diet for conservative management of chronic kidney disease: a systematic review and meta-analysis of controlled trials.
    J Cachexia Sarcopenia Muscle 2017 Nov 2. Epub 2017 Nov 2.
    Harold Simmons Center for Kidney Disease Research and Epidemiology, Division of Nephrology and Hypertension, University of California Irvine Medical Center, Orange, CA, USA.
    Background: Recent data pose the question whether conservative management of chronic kidney disease (CKD) by means of a low-protein diet can be a safe and effective means to avoid or defer transition to dialysis therapy without causing protein-energy wasting or cachexia. We aimed to systematically review and meta-analyse the controlled clinical trials with adequate participants in each trial, providing rigorous contemporary evidence of the impact of a low-protein diet in the management of uraemia and its complications in patients with CKD.

    Methods: We searched MEDLINE (PubMed) and other sources for controlled trials on CKD to compare clinical management of CKD patients under various levels of dietary protein intake or to compare restricted protein intake with other interventions. Read More

    [DIET CHARACTERISTICS IN PATIENTS WITH CHRONIC KIDNEY DISEASE].
    Acta Med Croatica 2016 12;70(4-5):275-81
    Because of the increasing number of patients, chronic kidney disease (CKD) has become a significant public health problem. As kidney function decreases, it is necessary to introduce certain dietary modifications. The aim was to investigate what is the appropriate approach to diet of CKD patients, which could contribute to slowing down progression of the disease. Read More

    The Impact of Trained Volunteer Mealtime Assistants on Dietary Intake and Satisfaction with Mealtime Care in Adult Hospital Inpatients: A Systematic Review.
    J Nutr Health Aging 2017 ;21(9):1038-1049
    F.F.A. Howson, University Hospital Southampton, Medicine for Older People, Tremona Rd, Southampton, Hants SO16 6YD, United Kingdom,
    Background: Malnutrition is common in hospital inpatients and is associated with increased morbidity and mortality. Insufficient assistance at mealtimes can contribute to this and therefore trained volunteer mealtime assistants may be of benefit.

    Objectives: To identify and review the current evidence for the impact of trained volunteer mealtime assistants on dietary intake and satisfaction with mealtime care in adult hospital inpatients. Read More

    NT-proBNP, Cardiometabolic Risk Factors, and Nutritional Status in Hemodialysis Patients.
    Int J Nephrol 2017 17;2017:1312547. Epub 2017 Sep 17.
    Centre de Dialyse AUDRA, Hôpital RICOU, Pointe-à-Pitre, Guadeloupe, France.
    Background: We aimed to evaluate the association between NT-proBNP and malnutrition in HD patients while taking into account the four established categories of parameters for diagnosis of protein energy wasting (PEW).

    Methods: A cross-sectional study was performed in Afro-Caribbean dialysis patients. One component in each of the 4 categories for the wasting syndrome was retained: serum albumin ≤ 38 g/L, BMI ≤ 23 Kg/m2, serum creatinine ≤ 818 µmol/L, and normalized protein catabolic rate (nPCR) ≤ 0. Read More

    Childhood stunting in relation to the pre- and postnatal environment during the first 2 years of life: The MAL-ED longitudinal birth cohort study.
    • Authors:
    PLoS Med 2017 Oct 25;14(10):e1002408. Epub 2017 Oct 25.
    Background: Stunting is the most prevalent manifestation of childhood malnutrition. To characterize factors that contribute to stunting in resource-poor settings, we studied a priori selected biological and social factors collected longitudinally in a cohort of newborns.

    Methods And Findings: We enrolled 1,868 children across 7 resource-poor settings in Bangladesh, Brazil, India, Nepal, Peru, South Africa, and Tanzania shortly after birth and followed them for 24 months between 2 November 2009 and 28 February 2014. Read More

    The role of nutrition in geriatric rehabilitation.
    Curr Opin Clin Nutr Metab Care 2018 Jan;21(1):14-18
    Department for Health Services Research, Assistance Systems and Medical Devices, Carl von Ossietzky University Oldenburg, Oldenburg, Germany.
    Purpose Of Review: To highlight the importance of nutrition in older adults undergoing a rehabilitation program. Geriatric rehabilitation aims at the recovery of physical abilities for a largely independent life in the community. The term 'geriatric rehabilitation' is wide and includes inpatient and ambulatory care as well as rehabilitation programs in hospitals, also outside geriatric wards. Read More

    Glycaemic response after intake of a high energy, high protein, diabetes-specific formula in older malnourished or at risk of malnutrition type 2 diabetes patients.
    Clin Nutr 2017 Oct 6. Epub 2017 Oct 6.
    CHU Bordeaux, Bordeaux, France.
    Background & Aims: Several studies with diabetes-specific formulas (DSFs) for hyperglycaemic patients in need of nutritional support have been conducted in non-malnourished patients, mainly comparing products with varying macronutrient compositions. Here, the effect of a high energy, high protein DSF on postprandial responses was compared to a product with a similar macronutrient composition in malnourished or at risk of malnutrition patients with type 2 diabetes.

    Methods: In this randomised, double-blind cross-over study, 20 patients were included. Read More

    Nutritional profile of hemodialysis patients concerning treatment time.
    J Bras Nefrol 2017 Jul-Sep;39(3):283-286
    Universidade Federal Fluminense.
    Introduction: The mortality of the population with chronic kidney disease (CKD) on hemodialysis (HD) is very high and the protein-energy malnutrition stands out as one of the most common consequences in relation to this condition.

    Objective: To evaluate the association between time of hemodialysis and nutritional parameters of patients.

    Methods: It is a cross-sectional study with secondary data, developed of the University Hospital of the Federal University of Juiz de Fora (HU/UFJF). Read More

    Nutritional Therapy in Liver Transplantation.
    Nutrients 2017 Oct 16;9(10). Epub 2017 Oct 16.
    Division of Hepato-Biliary-Pancreatic and Transplant Surgery, Department of Surgery, Graduate School of Medicine, Kyoto University, Kyoto 606-8501, Japan.
    Protein-energy malnourishment is commonly encountered in patients with end-stage liver disease who undergo liver transplantation. Malnutrition may further increase morbidity, mortality and costs in the post-transplantation setting. The importance of carefully assessing the nutritional status during the work-up of patients who are candidates for liver replacement is widely recognized. Read More

    Protein malnutrition after weaning disrupts peripheral clock and daily insulin secretion in mice.
    J Nutr Biochem 2017 Dec 4;50:54-65. Epub 2017 Sep 4.
    Department of Structural and Functional Biology, Institute of Biology, University of Campinas/UNICAMP, Campinas, SP, Brazil.
    Changes in nutritional state may alter circadian rhythms through alterations in expression of clock genes. Protein deficiency has a profound effect on body metabolism, but the effect of this nutrient restriction after weaning on biological clock has not been explored. Thus, this study aims to investigate whether the protein restriction affects the daily oscillation in the behavior and metabolic rhythms, as well as expression of clock genes in peripheral tissues. Read More

    Survival in Malnourished Older Patients Receiving Post-Discharge Nutritional Support; Long-Term Results of a Randomized Controlled Trial.
    J Nutr Health Aging 2017 ;21(8):855-860
    M.A.E. de van der Schueren, VU University Medical Center, De Boelelaan 1117, 1081 HV Amsterdam, the Netherlands, tel. +31-20-4443410,
    Background: Previous analyses have shown that a post-discharge individualized nutritional intervention had positive effects on body weight, lean body mass, functional limitations and fall incidents in malnourished older patients. However, the impact of this intervention on survival has not yet been studied.

    Objective: The objective of this randomized controlled study was to examine the effect of a post-discharge individualized nutritional intervention on survival in malnourished older patients. Read More

    Protein blend ingestion before allogeneic stem cell transplantation improves protein-energy malnutrition in patients with leukemia.
    Nutr Res 2017 Oct 25;46:68-77. Epub 2017 Aug 25.
    Institute of Food and Nutrition Development, Ministry of Agriculture, Beijing 100081, China. Electronic address:
    Severe protein-energy malnutrition (PEM) and skeletal muscle wasting are commonly observed in patients with acute leukemia. Recently, the ingestion of a soy-whey protein blend has been shown to promote muscle protein synthesis (MPS). Thus, we tested the hypothesis that the ingestion of a soy-whey blended protein (BP) may improve the PEM status and muscle mass in acute leukemia patients. Read More

    Prevalence and determinants of low protein intake in very old adults: insights from the Newcastle 85+ Study.
    Eur J Nutr 2017 Sep 25. Epub 2017 Sep 25.
    Newcastle University Institute for Ageing, Newcastle University, Newcastle upon Tyne, NE2 4AX, UK.
    Purpose: The very old (aged ≥ 85 years), fastest growing age group in most western societies, are at especially high risk of muscle mass and strength loss. The amount, sources and timing of protein intake may play important roles in the aetiology and management of sarcopenia. This study investigated the prevalence and determinants of low protein intake in 722 very old adults participating in the Newcastle 85+ Study. Read More

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