52,297 results match your criteria Prosthetic Heart Valves


A large-volume academic center retrospective audit of the temporal evolution of immediate breast reconstruction protocols and the effect on breast prosthetic infection.

J Plast Reconstr Aesthet Surg 2018 Nov 2. Epub 2018 Nov 2.

Department of Plastic Surgery, Johns Hopkins University School of Medicine, 601 N. Caroline St., Baltimore, MD 21287, United States.

Background: Complications of tissue expanders (TEs) in breast reconstruction are challenging. We sought to identify TE infection risks and acellular dermal matrix (ADM) and infection control protocol impacts on infection in a longitudinal study.

Methods: We retrospectively analyzed TE/implant reconstructions in 2004 (no ADM), 2009 (TE and ADM), 2013 (TE, ADM, and infection control protocol), and 2015 (TE, ADM, and infection control protocol). Read More

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November 2018
1 Read

Influence of limb alignment and prosthetic orientation on patient-reported clinical outcomes in total knee arthroplasty.

J Orthop Sci 2018 Dec 12. Epub 2018 Dec 12.

Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine, Kobe, Japan. Electronic address:

Background: The relationship between postoperative limb alignment and clinical outcomes in primary total knee arthroplasty (TKA) is well reported, but the instruments used to evaluate clinical outcomes of TKA are mainly scoring systems from the physician's viewpoint, not patient-reported outcomes. The purpose of this study was to investigate retrospectively the relationship between postoperative limb alignment and patient-reported clinical outcomes using the 2011 Knee Society Knee Scoring System (2011 KSS).

Methods: The present study included 155 knees of patients (median age, 74 years) who underwent primary TKA for varus osteoarthritis, with a mean follow-up period of 46 months. Read More

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December 2018

Is sonication of antibiotic-loaded cement spacers useful in two-stage revision of prosthetic joint infection?

J Microbiol Methods 2018 Dec 12. Epub 2018 Dec 12.

IRCSS Istituto Ortopedico Rizzoli, Bologna, Italy.

Background: In a two-stage exchange protocol for prosthetic joint infection (PJI), bacteria surviving over the antibiotic-loaded cement spacers may cause the persistence of infection with renewed clinical symptoms following the surgery. Culture after sonication of removed prosthesis is more sensitive than conventional periprosthetic tissue culture for the microbiological diagnosis of PJI. The aim of this study was to assess whether sonication of the spacer at the time of the second-stage procedure may improve the diagnosis of persistent PJI. Read More

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December 2018

Feasibility of transcatheter prosthetic paravalvular leakage closure: a single-center, exploratory safety evaluation study of transcatheter closure of prosthetic paravalvular regurgitation in Japan (STOP PARA study).

Gen Thorac Cardiovasc Surg 2018 Dec 14. Epub 2018 Dec 14.

Department of Cardiovascular Surgery, National Cerebral and Cardiovascular Center, Suita, Japan.

Objective: The standard treatment of prosthetic paravalvular leakage (PVL) accompanied by heart failure or hemolytic anemia is repeat open surgery. Although favorable outcomes for transcatheter prosthetic PVL closure in patients with a high surgical risk for repeat open surgery have been reported, procedural feasibility has not been examined in Japan.

Methods: From March 2015 to November 2015, transcatheter PVL closure in mitral position was performed in four patients (age range 41-78, three females) with high surgical risk due to history of repeated surgeries, chest radiation and reconstruction of the mitral annulus after debridement of abscess owing to infective endocarditis. Read More

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December 2018
2 Reads

Penile Prosthesis Reservoir Removal: Surgical Description and Patient Outcomes.

J Sex Med 2018 Dec 11. Epub 2018 Dec 11.

Division of Urology, Rutgers New Jersey Medical School, East Orange, NJ, USA. Electronic address:

Background: Removal of the penile prosthesis reservoir can be technically challenging because of its difficult locations either deep in the pelvis or high in the abdominal wall.

Aim: To describe a detailed surgical technique for reservoir removal through a penoscrotal approach.

Methods: We describe our preferred method for removal of prosthetic reservoir and present a retrospective review of patient outcomes after reservoir removal. Read More

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December 2018
1 Read

Comparative study of cultures and next-generation sequencing in the diagnosis of shoulder prosthetic joint infections.

J Shoulder Elbow Surg 2019 Jan;28(1):1-8

Department of Orthopaedic Surgery, Rothman Institute-Thomas Jefferson University, Philadelphia, PA, USA.

Background: Serum and synovial markers used to diagnose lower extremity prosthetic joint infection (PJI) have performed poorly for shoulder PJI. As a result, diagnosis is commonly reliant on the accuracy of positive or negative cultures. Next-generation sequencing (NGS) can sequence an entire bacterial genome. Read More

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January 2019

[Megaimplants of the Proximal Femur: Current Concepts].

Z Orthop Unfall 2018 Dec 14;156(6):685-691. Epub 2018 Dec 14.

Klinik und Poliklinik für Orthopädie und Sportorthopädie, Klinikum rechts der Isar, Technische Universität München.

In addition to their outstanding significance in the field of tumor orthopaedics, megaprostheses are becoming increasingly important for revision arthroplasty. Despite their wide application, the reported complication and failure rates remain high. The analysis of failure mechanisms roughly allows a breakdown into mechanical and non-mechanical causes; soft-tissue failure, loosening and periprosthetic infection play outstanding roles. Read More

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December 2018
2 Reads

In Vivo Photovoltaic Performance of a Silicon Nanowire Photodiode-Based Retinal Prosthesis.

Invest Ophthalmol Vis Sci 2018 Dec;59(15):5885-5892

Jacobs Retina Center at Shiley Eye Institute, Department of Ophthalmology, University of California, San Diego, California, United States.

Purpose: For more than 20 years, there has been an international, multidisciplinary effort to develop retinal prostheses to restore functional vision to patients blinded by retinal degeneration. We developed a novel subretinal prosthesis with 1512 optically addressed silicon nanowire photodiodes, which transduce incident light into an electrical stimulation of the remaining retinal circuitry. This study was conducted to evaluate the efficacy of optically driving the subretinal prosthesis to produce visual cortex activation via electrical stimulation of the retina. Read More

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December 2018
1 Read

Osseointegrated Percutaneous Prosthetic System for the Treatment of Patients With Transfemoral Amputation: A Prospective Five-year Follow-up of Patient-reported Outcomes and Complications.

J Am Acad Orthop Surg 2018 Dec 13. Epub 2018 Dec 13.

From the Centre for Advanced Reconstruction of Extremities (C.A.R.E.), Sahlgrenska University Hospital, Department of Orthopaedics, Institute for Clinical Sciences, The Sahlgrenska Academy, University of Gothenburg, Mölndal, Sweden (Dr. Brånemark, Dr. Hagberg, Mrs. Kulbacka-Ortiz, and Dr. Berlin), International Centre for Osseointegration Research, Education and Surgery (iCORES), Department of Orthopaedics, University of California, San Francisco, CA (Dr. Brånemark), and the Sahlgrenska University Hospital, Department of Orthopaedics, Institute for Clinical Sciences, The Sahlgrenska Academy, University of Gothenburg, Mölndal, Sweden (Dr. Rydevik).

Introduction: Direct skeletal attachment of prostheses has previously been shown to improve patient-reported outcome (PRO) measures of individuals with transfemoral amputation (TFA) at 2-year follow-up. This prospective study reports the outcomes at 5-year follow-up.

Methods: A total of 51 patients (55 legs) with TFA were included in a prospective study. Read More

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December 2018

Salivary creatinine and urea in patients with end-stage chronic kidney disease could not be used as diagnostic biomarkers for the effectiveness of dialysis treatment.

G Ital Nefrol 2018 Dec;35(6)

Department of Oral Surgery, Faculty of Dental medicine, Medical University, Plovdiv, Bulgaria.

Introduction: End-stage chronic kidney disease (CKD) is characterized by kidney failure with the organ's functions reduced or lost completely, where the kidneys are incapable of filtering excess fluids. Renal replacement therapy may be provided by peritoneal dialysis, hemodialysis or renal transplantation. Among the key indicators for tracking patients' current status are urea and creatinine levels. Read More

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December 2018

[Management of infection associated with prosthetic arthroplasty : What's new ?]

Rev Med Suisse 2018 Dec;14(631):2248-2253

Service de chirurgie orthopédique et traumatologie de l'appareil moteur, HUG, 1211 Genève 14.

Total hip and knee arthroplasties are associated with a risk of infection ranging between 0.5 and 2 %, and pose a difficult diagnosis and prolonged treatment for the infected patient. The treatment must be multidisciplinary, consisting of orthopaedic surgeons, infectious diseases specialists, and radiologists, aiming at an accurate diagnosis and appropriate decisions, adapted to the clinical situation of the patient. Read More

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December 2018

[Robotic surgery : the future of prosthetic surgery ?]

Rev Med Suisse 2018 Dec;14(631):2238-2242

Service d'orthopédie et traumatologie de l'appareil moteur, HUG, 1211 Genève 14.

Indications for hip and knee replacement will continue to grow over the next few years. Robotic systems have been developed since the early 1990s in order to optimize implant positioning, to potentially improve clinical results, and to reduce perioperative morbidity. Currently, the different available systems certainly improve the accuracy and reproducibility of prosthetic components placement. Read More

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December 2018

Repair of tricuspid papillary muscle rupture after percutaneous coronary intervention.

Authors:
Shinji Kanemitsu

Multimed Man Cardiothorac Surg 2018 Dec 6;2018. Epub 2018 Dec 6.

Department of Thoracic and Cardiovascular Surgery Mie University Graduate School of Medicine 2-174 Edobashi, Tsu, Mie 514-8507, Japan.

Papillary muscle rupture is a rare complication after myocardial infarction and almost all cases occur in the mitral valve papillary muscle. Tricuspid regurgitation development after right ventricular myocardial infarction caused by papillary muscle rupture is extremely rare.  In this video tutorial we present a 70-year-old man with massive tricuspid regurgitation caused by papillary muscle rupture after percutaneous stenting of the right coronary artery. Read More

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December 2018

Assessment of the influence of selected electrolytic polishing process parameters on the surface roughness of casts made of the CoCrMo alloy.

Dent Med Probl 2018 Dec 10. Epub 2018 Dec 10.

Department of Dental Propedeutics and Prophylaxis, Faculty of Medicine and Dentistry, Medical University of Warsaw, Poland.

Background: To fabricate some prosthetic restorations, such as metal alloy frameworks for removable partial dentures (RPDs), casting techniques must be used. The penultimate stage of the cast finishing procedure is electropolishing.

Objectives: The aim of the study was to assess the influence of selected electrolytic polishing process parameters on the resulting surface smoothness of the cobalt-chromium-molybdenum (CoCrMo) alloy. Read More

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December 2018

The functional loading of implants increases their stability: A retrospective clinical study.

Clin Implant Dent Relat Res 2018 Dec 13. Epub 2018 Dec 13.

Department of Stomatology I, Faculty of Medicine and Dentistry, University of the Basque Country, Leioa, Spain.

Purpose: To assess the difference in the evolution of implant stability values, determined by resonance frequency analysis (RFA), between two groups of implants subjected to two different loading protocols: immediate and delayed.

Materials And Methods: A retrospective clinical study was conducted, including a total of 93 implants placed in 38 patients. All implants corresponded to one of two models of the Klockner Implant System (Essential Cone and Vega) and were divided into two groups according to the loading protocol adopted: delayed loading in group A (>10 weeks) and immediate loading in group B (<48 hours). Read More

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December 2018

Clinical indices and local levels of inflammatory biomarkers in per-implant health of obese and nonobese individuals.

Clin Implant Dent Relat Res 2018 Dec 13. Epub 2018 Dec 13.

Department of Periodontology, Faculty of Dentistry, Ziauddin University, Karachi, Pakistan.

Background: Obesity seem to regulate peri-implant health. It is proposed that peri-implant crevicular fluid (PICF) levels of interleukin (IL)-1β and IL-6 are higher in obese as compared to nonobese individuals.

Objective: The purpose of the present clinico-laboratory study is to estimate and compare the clinical and radiographic indices and PICF levels of IL-1β and IL-6 among obese and nonobese patients. Read More

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December 2018

Explantation of infected thoracic endovascular aortic repair.

J Vasc Surg Cases Innov Tech 2018 Dec 4;4(4):307-310. Epub 2018 Dec 4.

Division of Vascular and Endovascular Surgery, University of Massachusetts Medical School, Worcester, Mass.

Prosthetic graft infection is a rare and serious complication of thoracic endovascular aortic repair associated with high mortality and posing unique challenges for treatment. The prosthetic graft infection is often identified late as patients present with mild nonspecific symptoms. We describe the successful medical management and surgical explantation of an infected thoracic endograft with an aorta-bronchial fistula, using an inline reconstruction with an antibiotic-soaked synthetic graft. Read More

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December 2018

Aneurysmal degeneration and rupture of deep vein conduit with formation of an arterial-vaginal fistula 13 years after creation of a femoral-femoral bypass.

J Vasc Surg Cases Innov Tech 2018 Dec 4;4(4):287-291. Epub 2018 Dec 4.

Department of Surgery, UT Southwestern Medical Center, Dallas, Tex.

The autologous deep vein is a suitable alternative to prosthetic or cadaveric grafts as a bypass conduit because of its superior durability and lower risk of complications. Aneurysmal degeneration of deep vein grafts is rarely seen but can potentially be fatal when it does occur. We describe the case of an 87-year-old woman who presented with acute vaginal bleeding due to the rupture of an aneurysmal femorofemoral bypass vein graft into the vagina. Read More

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December 2018

Comparison of implant survivability in primary 1- to 2-level lumbar fusion amongst opioid abusers and non-opioid abusers.

J Spine Surg 2018 Sep;4(3):568-574

Department of Neurological Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.

Background: Primary lumbar fusion (LF) is a treatment option for degenerative disc disease. The literature is limited regarding postoperative complications in opioid abusers undergoing LF. The purpose of this study was to compare 2-year short term implant-related complications, infection rates, 90-day readmission rates, in-hospital length of stay, and cost of care amongst opioid abusers (OAS) and non-opioid abusers (NAS) undergoing primary 1- to 2-level primary lumbar fusion (1-2LF). Read More

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September 2018
1 Read

Trends in cervical disc arthroplasty and revisions in the Medicare database.

J Spine Surg 2018 Sep;4(3):522-528

East Coast Orthopedics, Pompano, FL, USA.

Background: Due to increased postoperative complications with anterior cervical discectomy and fusion (ACDF), there has been an increasing interest in the use of cervical disc arthroplasty (CDA). Advancements in prosthetic designs and techniques have improved patient reported outcome measurements and minimized revision rates. There is a paucity in the literature regarding recent trends in CDA utilization and revision rates. Read More

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September 2018
1 Read

Anchorage possibilities in case of a unilateral maxillary defect using the concept of Strategic Implant.

Natl J Maxillofac Surg 2018 Jul-Dec;9(2):235-239

Reg-Med Dental Clinic, Rzeszowska, Zary, Poland.

The aim of this article was to present the treatment method applied to a patient who suffered from a multiple fracture of the right maxilla, as a result of an accident that happened to him at an early age. The main consequence of this injury was an inhibited growth of the maxillary bone segment due to the lack of functional stimulus. The treatment consisted of four phases: the removal of all the teeth in the upper right maxilla, the immediate restoration with bicortical implants, the immediate prosthetic rehabilitation, and closing the oroantral communication. Read More

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December 2018
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Prosthodontic rehabilitation of a sub-total maxillectomy defect with a definitive hollow obturator prosthesis using the modified lost-wax concept: A novel technique.

Natl J Maxillofac Surg 2018 Jul-Dec;9(2):225-228

Department of Prosthodontics, Christian Dental College, Ludhiana, Punjab, India.

Squamous cell carcinoma (SCC) of the oral cavity is relatively common in the Indian subcontinent with surgical resection and adjuvant radiotherapy/chemotherapy being the treatment modality of choice. Prosthetic rehabilitation with an obturator following resection is more economical and yields satisfactory results. Better patient acceptance and comfort necessitates hollowing the prosthesis to a great extent. Read More

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December 2018

Is Operative Time a Predictor for Post-Operative Infection in Primary Total Knee Arthroplasty?

J Arthroplasty 2018 Nov 22. Epub 2018 Nov 22.

Department of Orthopaedic Surgery, Cleveland Clinic Foundation, Cleveland, OH.

Background: The purpose of this study is to identify factors affecting operative times and to evaluate the associations of operative times with prosthetic joint infections (PJIs) and surgical site infections (SSIs) in primary total knee arthroplasty.

Methods: A total of 11,840 primary total knee arthroplasties with a mean 2-year post-operative follow-up were studied. Operative times were analyzed both as categorical and continuous variables. Read More

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November 2018

Multicenter Retrospective Analysis of Implant Overdentures Delivered with Different Design and Attachment Systems: Results Between One and 17 Years of Follow-Up.

Dent J (Basel) 2018 Dec 11;6(4). Epub 2018 Dec 11.

Department of Clinical, Surgical, Diagnostic and Pediatric Sciences, School of Dentistry, University of Pavia, 27100 Pavia, Italy.

Purpose: To analyze implant and prosthetic survival rates, complications, patient satisfaction, and biological parameters of patients rehabilitated with implant overdentures (IOV) on splinted and nonsplinted implants and different attachment systems, in function for one to 17 years.

Methods: This retrospective study evaluated data collected from patients rehabilitated with implant overdentures between January 2001 and December 2016 in nine different centers. Outcome measures were implant and prosthetic success rates, mechanical complications, marginal bone loss (MBL), oral health impact profile (OHIP), bleeding on probing, and plaque index. Read More

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December 2018

Ultrasonic vs Drill Implant Site Preparation: Post-Operative Pain Measurement Through VAS, Swelling and Crestal Bone Remodeling: A Randomized Clinical Study.

Materials (Basel) 2018 Dec 11;11(12). Epub 2018 Dec 11.

Department of Medical Sciences, University of Trieste, 34127, Trieste, Italy.

: Piezosurgery is a surgical procedure that is able to perform osteotomies by a micrometric and selective cut of the bone tissue. The objective of this investigation was to evaluate two different techniques; an ultrasonic device, and a drill approach for implant site preparation. : A total of fifty patients were recruited for the randomized clinical trial to receive dental implants for fixed prosthetic restoration in the posterior mandible and were allotted to two groups. Read More

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December 2018

Emergence of daptomycin non-susceptible coagulase-negative Staphylococci in patients with cardiovascular device infections: Two cases report investigated by whole genome analysis.

Medicine (Baltimore) 2018 Dec;97(49):e13487

Division of Infection Control and Prevention, Osaka University Hospital.

Rationale: Daptomycin (DAP) is a key drug for treating severe Staphylococcus infections. The emergence of DAP non-susceptible Staphylococcus aureus has been widely recognized in clinical situations, although the clinical status of DAP non-susceptible coagulase-negative Staphylococcus (CoNS) infections is unclear. We encountered 2 cases of cardiovascular device infections that were associated with DAP non-susceptible CoNS. Read More

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December 2018

Femoral Intramedullary Alignment in Total Knee Arthroplasty: Indications, Results, Pitfalls, Alternatives, and Controversies.

J Knee Surg 2018 Dec 13. Epub 2018 Dec 13.

Department of Orthopedic Surgery, New England Baptist Hospital, Boston, Massachusetts.

While femoral intramedullary alignment has been found to be the most accurate and reproducible method for proper femoral component orientation in total knee arthroplasty, certain situations preclude the use of intramedullary alignment, such as ipsilateral long-stem total hip arthroplasty, femoral shaft deformity (congenital or post-traumatic), capacious femoral canal, and retained hardware. These cases require alternative alignment guides, that is, extramedullary alignment. The purpose of this study was to determine the accuracy of intramedullary alignment in reproducing the femoral anatomic axis. Read More

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December 2018

Post-sternotomy deep wound infection following aortic surgery: wound care strategies to prevent prosthetic graft replacement.

Eur J Cardiothorac Surg 2018 Dec 12. Epub 2018 Dec 12.

Department of Cardiovascular Surgery, Kobe University Graduate School of Medicine, Kobe, Japan.

Objectives: The aim of this study was to evaluate the early and long-term outcomes of our multidisciplinary strategy for treating deep sternal wound infection after aortic grafting, which consisted of debridement by a plastic surgeon, negative pressure wound therapy with continuous irrigation and chest wall reconstruction.

Methods: We performed a retrospective analysis of 18 patients who had a deep sternal wound infection following aortic grafting through a median sternotomy between January 2009 and December 2017. All patients had organisms cultured from mediastinal tissue within 2 months from the initial aortic surgery. Read More

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December 2018

Randomized Controlled Clinical Trial of All-Ceramic Single-Tooth Implant Reconstructions Using Modified Zirconia Abutments: Results at 5 Years After Loading.

Int J Periodontics Restorative Dent 2019 Jan/Feb;39(1):17-27

The objective of this trial study was to assess whether submucosal veneering of internally connected zirconia abutments influences clinical, radiographic, and technical outcomes of single-tooth implant-borne reconstructions at 5 years after loading. A total of 20 patients with 20 single-tooth implants in the anterior or premolar area of the maxilla or mandible were included. The implants were randomly restored with fixed single-tooth reconstructions using either pink-veneered customized zirconia abutments (test group = 10) or nonveneered customized zirconia abutments (control group = 10). Read More

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December 2018

LbL-assembled gentamicin delivery system for PMMA bone cements to prolong antimicrobial activity.

PLoS One 2018 13;13(12):e0207753. Epub 2018 Dec 13.

School of Pharmacy and Pharmaceutical Science, Cardiff University, Cardiff, United Kingdom.

Introduction: Antibiotic-loaded poly(methyl methacrylate) bone cements (ALBCs) are widely used in total joint replacement (TJR), for local delivery of antibiotics to provide prophylaxis against prosthetic joint infections (PJI). One of the shortcomings of the current generation of ALBCs is that the antibiotic release profile is characterized by a burst over the first few hours followed by a sharp decrease in rate for the following several days (often below minimum inhibitory concentration (MIC)), and, finally, exhaustion (after, typically, ~ 20 d). This profile means that the ALBCs provide only short-term antimicrobial action against bacterial strains involved PJI. Read More

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December 2018

[A 3-D reprint of the prosthetic hand of Götz of the Iron Hand].

MMW Fortschr Med 2018 Dec;160(21-22):71-73

Hochschule für Technik, Wirtschaft und Medien, Offenburg, Deutschland.

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December 2018

Facile folding of insulin variants bearing a prosthetic C-peptide prepared by α-ketoacid-hydroxylamine (KAHA) ligation.

Chem Sci 2018 Nov 11;9(44):8388-8395. Epub 2018 Sep 11.

Laboratorium für Organische Chemie , Department of Chemistry and Applied Biosciences , ETH Zürich , 8093 Zürich , Switzerland . Email: ; http://www.bode.ethz.ch/.

The chemical synthesis of insulin is an enduring challenge due to the hydrophobic peptide chains and construction of the correct intermolecular disulfide pattern. We report a new approach to the chemical synthesis of insulin using a short, traceless, prosthetic C-peptide that facilitates the formation of the correct disulfide pattern during folding and its removal by basic treatment. The linear precursor is assembled by an ester forming α-ketoacid-hydroxylamine (KAHA) ligation that provides access to the linear insulin precursors in good yield from two readily prepared segments. Read More

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November 2018

Sonication Culture of Antimicrobial Agent-Containing Cement Spacers Removed During Staged Revisions for Arthroplasty Infection.

J Clin Microbiol 2018 Dec 12. Epub 2018 Dec 12.

Division of Infectious Diseases, Department of Medicine, Mayo Clinic, Rochester, MN.

Diagnosis of persistent infection at the time of reimplantation for staged revision of infected arthroplasties is challenging. Implant sonication culture for the diagnosis of prosthetic joint infection (PJI) has improved sensitivity compared to standard periprosthetic tissue culture. We report our experience with periprosthetic tissue culture and sonication culture of antimicrobial agent-containing cement spacers (ACSs) collected during second stages of staged revisions for arthroplasty infection. Read More

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December 2018

Surgical Scar Recurrence of Bone Metastases to the Femur: A Case Report.

Cureus 2018 Sep 29;10(9):e3385. Epub 2018 Sep 29.

Radiation Oncology, The Ottawa Hospital & University of Ottawa, Ottawa, CAN.

We report the case of a woman who presented with breast cancer metastases to the femur causing pathologic fracture of the femoral neck requiring surgery. She received adjuvant radiotherapy to the femur at that time that did not include the surgical scar tract. Almost four years after her surgery she presented with biopsy proven skin recurrence of breast cancer on the skin overlying her incision from her femoral surgery. Read More

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September 2018

Motor unit drive: A neural interface for real-time upper limb prosthetic control.

J Neural Eng 2018 Oct 24. Epub 2018 Oct 24.

Delsys Inc. and Altec Inc., Natick, Massachusetts, UNITED STATES.

Objective: Modern prosthetic limbs have made strident gains in recent years, incorporating terminal electromechanical devices that are capable of mimicking the human hand. However, access to these advanced control capabilities has been prevented by fundamental limitations of neural interfaces, which have remained virtually unchanged for nearly five decades. Consequently, nearly 23% of adults and 32% of children with major traumatic or congenital upper-limb loss abandon regular use of their myoelectric prostheses. Read More

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October 2018

Micro-channel sieve electrode for concurrent bidirectional peripheral nerve interface. Part B: Stimulation.

J Neural Eng 2018 Nov 9. Epub 2018 Nov 9.

Department of Biomedical Engineering, Washington University in St Louis, Campus Box 1097, One Brookings Drive, Saint Louis, Missouri, 63130-4899, UNITED STATES.

Objective: Successful use of a prosthetic limb by an amputee is facilitated by haptic feedback - both a sense of touch and proprioception. Stimulating afferent fibers within peripheral nerves has been shown to provide somatosensation enabling amputees to modulate the control of prosthetic limbs. Peripheral nerve interfaces (PNIs) have also been used to decode patients' motor intentions. Read More

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November 2018

Micro-channel sieve electrode for concurrent bidirectional peripheral nerve interface. Part A: Recording.

J Neural Eng 2018 Nov 9. Epub 2018 Nov 9.

Department of Biomedical Engineering, Washington University in St Louis, Campus Box 1097, One Brookings Drive, Saint Louis, Missouri, 63130-4899, UNITED STATES.

Objective: Advancement in prosthetic limb technology requires corresponding improvements in the capability of the amputee to naturally control the device via original motor pathways while simultaneously receiving haptic feedback via sensory pathways. Recording efferent axonal activity using a peripheral neural interface (PNI) allows a good tradeoff between invasiveness and selectivity while possibly preserving the phenomenology of controlling the original limb. One such PNI, the thin-film transverse intrafascicular multichannel electrode (tfTIME), has been shown to be successful in controlling powered prosthetics. Read More

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November 2018

[Analysis of risk factors of 19 fractured implants].

Zhonghua Kou Qiang Yi Xue Za Zhi 2018 Dec;53(12):815-820

Fourth Clinical Division, Peking University School and Hospital of Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Laboratory for Digital and Material Technology of Stomatology & Beijing Key Laboratory of Digital Stomatology, Beijing 100025, China.

To analyze the incidence and possible risk factors of 19 fractured implants out of 8 468 implants in 3 184 cases. During the 22-year clinical practice, clinical records of 18 patients with 19 fractured implants in 3 184 cases with 8 468 implants were analyzed to determine the following factors: location of the fractured implants, prosthodontics option, date of implant fracture, dimensions of fractured implants, complications prior to implant fracture and parafunctional habit. An evaluation of fractured implants was performed to identify possible factors that may predispose an implant to a higher risk of fracture. Read More

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December 2018
1 Read

Comparative biomechanical evaluation of two technologically different microprocessor-controlled prosthetic knee joints in safety-relevant daily-life situations.

Biomed Tech (Berl) 2018 Dec 12. Epub 2018 Dec 12.

Ottobock SE & Co. KGaA, Clinical Research and Services, Research Biomechanics, 37075 Göttingen, Germany.

Safety-relevant gait situations (walking on stairs and slopes, walking backwards, walking with small steps, simulated perturbations of swing phase extension) were investigated in a motion analysis laboratory with six unilateral transfemoral amputees using two different microprocessor-controlled prosthetic knee joints (Rheo Knee XC, C-Leg). A randomized crossover design was chosen. The study results imply that the performance and safety potential of a microprocessor-controlled knee joint can be associated with the individual control algorithms and the technological concepts that are implemented to generate motion resistances for controlling flexion and extension movements. Read More

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December 2018

Parallelism of Dental Implants.

Authors:
Dennis Flanagan

J Oral Implantol 2018 Dec 12. Epub 2018 Dec 12.

1 Connecticut Dental Groups Pres n/a Connecticut Dental Groups.

Parallelism in dental implant positioning may not be detrimental. Read More

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December 2018

On the development of optical peripheral nerve interfaces.

Neural Regen Res 2019 Mar;14(3):425-436

Department of Bioengineering, University of Colorado Denver | Anschutz Medical Campus, Aurora, CO, USA.

Limb loss and spinal cord injury are two debilitating conditions that continue to grow in prevalence. Prosthetic limbs and limb reanimation present two ways of providing affected individuals with means to interact in the world. These techniques are both dependent on a robust interface with the peripheral nerve. Read More

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March 2019
1 Read

Preoperative valgus deformity has twice the risk of failure as compared to varus deformity after total knee arthroplasty.

Knee Surg Sports Traumatol Arthrosc 2018 Dec 11. Epub 2018 Dec 11.

1st Orthopaedic and Traumatologic Clinic, IRCCS Istituto Ortopedico Rizzoli, Via Giulio Cesare Pupilli 1, 40136, Bologna, Italy.

Purpose: The aim of this study was to assess whether preoperative valgus or varus deformity affected survivorship after total knee arthroplasty (TKA) and to quantify the risk factors for implant failure in a registry-based population.

Methods: The Emilia-Romagna Registry of Prosthetic Orthopedic Implants was examined regarding TKAs performed on patients with a preoperative diagnosis of valgus or varus deformity. Demographics, implant characteristic and survivorships were investigated and compared. Read More

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December 2018

Prevention of postoperative bleeding in hip fractures treated with prosthetic replacement: efficacy and safety of fibrin sealant and tranexamic acid. A randomised controlled clinical trial (TRANEXFER study).

Arch Orthop Trauma Surg 2018 Dec 11. Epub 2018 Dec 11.

Public Health and Clinical Epidemiology Service-Iberoamerican Cochrane Centre, IIB Sant Pau. CIBERESP, Barcelona, Spain.

Introduction: We assessed the efficacy of fibrin sealant (FS) and tranexamic acid (TXA) administered topically in patients with a hip fracture treated with prosthetic replacement.

Materials And Methods: Parallel, multicentre, open label, randomised, clinical trial. We compared three interventions to reduce blood loss: (1) 10 ml of FS, (2) 1 g of topical TXA, both administered at the end of the surgery, and (3) usual haemostasis (control group). Read More

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December 2018
2 Reads

Arthroscopic treatment of osteochondral knee defects with resorbable biphasic synthetic scaffold: clinical and radiological results and long-term survival analysis.

Int Orthop 2018 Dec 11. Epub 2018 Dec 11.

Unità Operativa C.A.S.C.O, IRCCS Istituto Ortopedico Galeazzi, 20161, Milan, Italy.

Purpose: The aim of our study is to evaluate the long-term results in patients treated with a fully arthroscopic TruFit system for osteochondral lesions of the femoral condyle, analyzing the clinical and radiological outcomes, survival rate, complications, and correlations.

Methods: The study included all patients treated with the TruFit system with a full-thickness focal lesion of the knee cartilage (grade IV according to the ICRS classification), entirely arthroscopically with a minimum follow-up of five years. All patients were evaluated clinically prior to surgery (T) and at two consecutive follow-ups (T 36. Read More

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December 2018
1 Read

A new classification for proximal femur bone defects in conservative hip arthroplasty revisions.

Int Orthop 2018 Dec 11. Epub 2018 Dec 11.

Orthopaedic and Traumatologic Department, Santo Spirito General Hospital, Rome, Italy.

Introduction: In the last three decades, total hip replacement in young patient became a habitual procedure. Principles of bone preservation are pushing many surgeons to implant conservative femoral components in patient younger than 65 years. Despite an overall good survivorship and clinical outcomes of conservative implants, failed cases are reported and the need to revise a conservative femoral component became an occasional procedure (with high prevalence of failed resurfacing implants). Read More

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December 2018
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Mandibular reconstruction with a ready-made type and a custom-made type titanium mesh after mandibular resection in patients with oral cancer.

Maxillofac Plast Reconstr Surg 2018 Dec 25;40(1):35. Epub 2018 Nov 25.

Department of Oral and Maxillofacial Surgery, School of Dentistry, Pusan National University, 20, Geumo-ro, Mulgeum-eup, Yangsan, Gyeongsangnam-do South Korea.

Background: After the resection at the mandibular site involving oral cancer, free vascularized fibular graft, a type of vascularized autograft, is often used for the mandibular reconstruction. Titanium mesh (T-mesh) and particulate cancellous bone and marrow (PCBM), however, a type of non-vascularized autograft, can also be used for the reconstruction. With the T-mesh applied even in the chin and angle areas, an aesthetic contour with adequate strength and stable fixation can be achieved, and the pores of the mesh will allow the rapid revascularization of the bone graft site. Read More

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December 2018
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Initial osteoblast adhesion and subsequent differentiation on zirconia surfaces are regulated by integrins and heparin-sensitive molecule.

Int J Nanomedicine 2018 19;13:7657-7667. Epub 2018 Nov 19.

Division of Advanced Prosthetic Dentistry, Graduate School of Dentistry, Tohoku University, Sendai, Japan.

Purpose: It is well known that zirconia materials have good biocompatibility; however, little is known regarding the mechanism by which cells attach to these materials. The purpose of this study is to elucidate the mechanism of cell attachment.

Materials And Methods: In this study, we examined the surface characteristics of ceria-stabilized zirconia/alumina nanocomposite (NANOZR), yttria-stabilized zirconia (Y-TZP) and commercially pure titanium (CpTi), and we evaluated the initial response of osteoblast-like cells to them with different inhibitors. Read More

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November 2018

Resection of the Inferior Vena Cava for Retroperitoneal Sarcoma: Six Cases and a Review of Literature.

Indian J Surg Oncol 2018 Dec 19;9(4):538-546. Epub 2018 Jul 19.

1Gastrointestinal Surgical Oncology, Department of Surgical Oncology and HPB services, Tata Memorial Hospital, Dr. E Borges Rd., Parel (E), Mumbai, 400012 India.

Resection of the inferior vena cava (IVC) for malignancy is a technically demanding procedure. We present a series of six cases of resection of the IVC for retroperitoneal sarcomas, four of which were primary caval tumors. We outline the technical difficulties faced in these complex procedures and discuss the oncological outcomes of these rare tumors. Read More

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December 2018

Functional performance and safety of bone-anchored prostheses in persons with a transfemoral or transtibial amputation: a prospective one-year follow-up cohort study.

Clin Rehabil 2018 Dec 12:269215518815215. Epub 2018 Dec 12.

4 Department of IQ Healthcare, Radboud Institute for Health Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.

Objectives:: (1) To compare level of function, activity, health-related quality of life (HRQoL) and satisfaction in persons with a lower extremity amputation before surgery and 6- and 12-months after implantation of an osseointegration implant and (2) to report adverse events.

Design:: Prospective cohort study.

Setting:: University medical centre. Read More

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December 2018

Mechanical loading releases osteoclastogenesis-modulating factors through stimulation of the P2X7 receptor in hematopoietic progenitor cells.

J Cell Physiol 2018 Dec 7. Epub 2018 Dec 7.

Department of Clinical and Experimental Medicine, Division of Cell Biology, Linköping University, Linköping, Sweden.

Mechanical instability of bone implants stimulate osteoclast differentiation and peri-implant bone loss, leading to prosthetic loosening. It is unclear which cells at the periprosthetic interface transduce mechanical signals into a biochemical response, and subsequently facilitate bone loss. We hypothesized that mechanical overloading of hematopoietic bone marrow progenitor cells, which are located near to the inserted bone implants, stimulates the release of osteoclast-inducing soluble factors. Read More

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December 2018
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