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Diagnostics (Basel) 2022 Jun 15;12(6). Epub 2022 Jun 15.

Department of Neurosciences, Reproductive Sciences and Odontostomatology, University of Naples Federico II, 80130 Naples, Italy.

The management of patients with prostate cancer (PCa) and previous or synchronous colorectal cancer (CRC) represents a challenging issue. A systematic review was performed in May 2022 to summarize available evidence about the diagnosis, management, and outcomes of these patients. Twenty-seven studies involving 252 patients were identified. Read More

Eur Urol Open Sci 2022 Jul 23;41:55-62. Epub 2022 May 23.

Department of Emergency and Organ Transplantation - Urology Unit, Aldo Moro University, Bari, Italy.

Background: Radical prostatectomy (RP) represents the standard of care for the treatment of patients with organ-confined prostatic cancer. Historically, perineal RP has been described as the first surgical approach for the complete removal of the prostatic gland. In the past years, robotic techniques provided some technical advantages that allow resuming alternative approaches, such as robotic radical perineal prostatectomy (r-RPP). Read More

Urologe A 2022 Apr 5. Epub 2022 Apr 5.

Zentrum für Urologische Rehabilitation, Klinik am Kurpark, Ziergartenstr. 19, 34537, Bad Wildungen-Reinhardshausen, Deutschland.

Purpose: Based on the work of Lent et al., the aim of this study was to compare and to evaluate the 2009 outcomes of maintaining continence after radical prostatectomy (rp) with those of patients from 2016.

Patients And Methods: The data of all patients who underwent follow-up treatment 1 to 8 weeks after rp in 2016 (n = 1392) were evaluated by quantitative measuring all day incontinence under a defined graduation and compared to the results of 2009 (n = 1750). Read More

Asian J Endosc Surg 2022 Mar 16. Epub 2022 Mar 16.

Department of Gastroenterological Surgery, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.

Introduction: The best surgical technique for rectal cancer invading the prostate remains controversial. Rectal resection with en bloc prostatectomy using a standard retropubic approach is an option but has disadvantages. We report a new surgical procedure applying Retzius-sparing robot-assisted radical prostatectomy. Read More

Int J Surg Case Rep 2022 Mar 25;92:106856. Epub 2022 Feb 25.

Division of Gastrointestinal Surgery, Department of Surgery, Asahikawa Medical University, 2-1, Midorigaoka-Higashi, Asahikawa 078-8510, Japan.

Introduction: Rectourethral fistula (RUF) after prostatectomy is a rare complication; however, when it occurs it is likely to be intractable and treatment requires surgical closure of the fistula. Several approaches to fistula closure have been reported, but there is no established treatment.

Case Presentation: The patient was a 66-year-old man who had undergone robot-assisted laparoscopic radical prostatectomy for prostate cancer. Read More

Int Neurourol J 2021 Sep 9;25(3):263-270. Epub 2021 Mar 9.

Department of Urology, Stanford University Medical Center, Stanford, CA, USA.

Purpose: This study aimed to examine the prevalence of surgery for postprostatectomy incontinence (PI) following minimally invasive surgery compared to conventional open surgery for prostate cancer.

Methods: This retrospective cohort study used the Florida State Ambulatory Surgery and State Inpatient Databases, 2008 to 2010, radical prostatectomy (RP) patients were identified using International Classification of Diseases (ICD)-9/10 procedure codes and among this cohort, PI was identified also using ICD-9/10 codes. Surgical approaches included minimally invasive (robotic or laparoscopic) versus open (retropubic or perineal) RP. Read More

BMC Urol 2021 Jan 28;21(1):12. Epub 2021 Jan 28.

Blanquerna School of Health Science-Universitat Ramon Llull, Barcelona, Spain.

Background: Radical prostatectomy is the gold standard treatment for men with localized prostate cancer. This technique is associated with post-operative urinary incontinence. Pelvic floor physiotherapy is a conservative, painless and economical treatment for this specific situation. Read More

Eur Urol 2021 03 21;79(3):384-392. Epub 2020 Dec 21.

Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH, USA. Electronic address:

Background: Radical perineal prostatectomy (RPP) has been revived with the advent of single-port (SP) robotic surgery. However, its interest and precise role need to be evaluated and better defined.

Objective: To describe in detail the technique of SP-RPP and compare initial perioperative outcomes with those of multiport robot-assisted transperitoneal radical prostatectomy (MP-RARP). Read More

J Contemp Brachytherapy 2020 Oct 30;12(5):492-496. Epub 2020 Oct 30.

Department of Radiotherapy, IEO European Institute of Oncology IRCCS, Milan, Italy.

Perineal seeding of tumor cells from prostate cancer (PCa) is very rare, and no standard treatment exists for this atypical presentation with no evidence of distant metastases. Local excision or external beam radiotherapy are used as local salvage treatments for such perineal masses, including those occurring after biopsy, surgery, or interstitial brachytherapy. We report on a patient who presented no evidence of disease and no late urinary or gastrointestinal toxicities at 58 months after receiving high-dose-rate brachytherapy (HDR-BT) for perineal recurrence of PCa after radical prostatectomy and salvage external beam radiotherapy. Read More

Curr Opin Urol 2021 01;31(1):11-17

Department of Emergency and Organ Transplantation -Urology, Andrology, and Kidney Transplantation Unit, University of Bari 'Aldo Moro', Bari, Italy.

Purpose Of Review: To provide an updated review of robotic radical perineal prostatectomy (r-RPP) with emphasis on the recent advances in terms of surgical technique, outcomes, and new robotic platforms.

Recent Finding: The technological innovations in the urological field have been applied to radical prostatectomy with the aim of preserving important anatomical structures and reduce patients' morbidity and mortality. In recent years, robotic surgery contributed to resurge radical perineal prostatectomy. Read More

Urologe A 2021 Aug;60(8):1039-1050

Lehrstuhl für Urologie, Klinikum der Universität Regensburg, Franz-Josef-Strauß-Allee 11, 93053, Regensburg, Deutschland.

The question of what came first-in this case the diagnosis of prostate cancer or its therapy-seems absurd at first glance and is reminiscent of the classic metaphor-like problem that preoccupied the Greek writer Plutarch (45-125). Today it is a matter of course that a reliable diagnosis is made before treating a disease, but this must be viewed as inconsistent in medical history. The beginnings of radical prostatectomy for the treatment of prostate cancer, like the first surgical therapies for kidney and bladder tumors, can be located in the pioneering period of organ surgery in the German Empire (1871-1918). Read More

Turk J Urol 2021 Jan 1;47(1):51-57. Epub 2021 Oct 1.

Department of Urology, Bakırköy Dr. Sadi Konuk Training and Research Hospital, İstanbul, Turkey.

Objective: Vesicourethral anastomotic stenosis (VUAS) is frequently seen after prostate surgery because of various operative and postoperative factors. In this study, we aimed to present our results of perineoscopic bladder neck reconstruction, which is a new technique of the perineal approach in the treatment of patients with VUAS after prostate cancer surgery.

Material And Methods: Sixteen consecutive patients who underwent perineoscopic bladder neck reconstruction in our clinic between July 2017 and March 2019 were included in the study. Read More

Urol Oncol 2020 08 3;38(8):650-660. Epub 2020 Jun 3.

Lee Kong Chian School of Medicine, Nanyang Technology University, Singapore; Department of Diagnostic Radiology, Tan Tock Seng Hospital, Singapore. Electronic address:

Targeted biopsy using multiparametric magnetic resonance imaging increases the detection rate of clinically significant prostate cancer (csCaP). In this meta-analysis, we compare the diagnostic accuracy of transrectal (TR) vs transperineal (TP) approaches for MRI-guided software fusion biopsy (FB) in the detection of csCaP. A literature search was performed in PubMed, Cochrane and Embase electronic databases up until July 2019 following the preferred reporting items for systematic review and meta-analysis system. Read More

BJU Int 2021 01 2;127(1):122-130. Epub 2020 Aug 2.

Department of Urology, San Giovanni Battista Hospital, Città della Salute e della Scienza and University of Turin, Turin, Italy.

Objective: To assess the outcomes of multiparametric magnetic resonance imaging (mpMRI) transperineal targeted fusion biopsy (TPFBx) under local anaesthesia.

Patients And Methods: We prospectively screened 1327 patients with a positive mpMRI undergoing TPFBx (targeted cores and systematic cores) under local anaesthesia, at two tertiary referral institutions, between September 2016 and May 2019, for inclusion in the present study. Primary outcomes were detection of clinically significant prostate cancer (csPCa) defined as (1) International Society of Urological Pathologists (ISUP) grade >1 or ISUP grade 1 with >50% involvement of prostate cancer (PCa) in a single core or in >2 cores (D1) and (2) ISUP grade >1 PCa (D2). Read More

Transl Androl Urol 2020 Apr;9(2):848-855

Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH, USA.

Background: To describe our step-by-step techniques for single-port robotic-assisted extraperitoneal and perineal radical prostatectomy as recent technical advancements in this field.

Methods: An English-language literature review was done using search terms including extraperitoneal, transperineal, single-port, robotic surgery, prostate cancer, radical prostatectomy in various combinations. Unique features of the da Vinci SP platform are discussed. Read More

BJU Int 2020 08 19;126(2):280-285. Epub 2020 May 19.

Department of Urology, Guy's and Saint Thomas' NHS Foundation Trust, London, UK.

Objectives: To assess whether targeted cognitive freehand-assisted transperineal biopsies using a Precisionpoint device still require additional systematic biopsies to avoid missing clinically significant prostate cancer, and to investigate the benefit of a quadrant-only biopsy approach to analyse whether a quadrant or extended target of the quadrant containing the target only would have been equivalent to systematic biopsy.

Patients And Methods: Patients underwent combined systematic mapping and targeted transperineal prostate biopsies at a single institution. Biopsies were performed using the Precisionpoint device (Perineologic, Cumberland, MD, USA) under either local anaesthetic (58%, 163/282), i. Read More

Urol Int 2020 14;104(9-10):710-715. Epub 2020 Apr 14.

Department of Urology, Shanghai Changhai Hospital, Naval Medical University, Shanghai, China,

Purpose: To investigate the feasibility and surgical technique of robotic perineal radical prostatectomy (RPRP).

Materials And Methods: We retrospectively analyzed 6 consecutive patients diagnosed with prostate cancer from December 2018 to May 2019 who underwent RPRP at our center. Perioperative outcomes were recorded for safety and feasibility analysis. Read More

BJU Int 2020 07 1;126(1):55-64. Epub 2020 May 1.

Department of Urology, San Luigi Gonzaga Hospital, University of Turin, Turin, Italy.

Objective: To summarize the clinical experiences with single-port (SP) robot-assisted radical prostatectomy (RARP) reported in the literature and to describe the peri-operative and short-term outcomes of this procedure.

Material And Methods: A systematic review of the literature was performed in December 2019 using Medline (via PubMed), Embase (via Ovid), Cochrane databases, Scopus and Web of Science (PROSPERO registry number 164129). All studies that reported intra- and peri-operative data on SP-RARP were included. Read More

Arch Esp Urol 2020 Apr;73(3):236-241

Department of Urology. University of Health Sciences. Bakirkoy Dr. Sadi Konuk Training and Research Hospital. Istanbul. Turkey.

Objective: To present our results of first 12 patients on whom we performed gasless robotic perineal radical prostatectomy (r-PRP).

Methods: We performed gasless r-PRP on 12 patients between August 2018 and October 2018. Multiparametric magnetic resonance imaging was performed forall patients to exclude local advanced disease. Read More

Int Braz J Urol 2020 May-Jun;46(3):434-435

Instituto do Câncer do Estado de São Paulo, Faculdade de Medicina da Universidade de São Paulo - USP, São Paulo, SP, Brasil.

Int Braz J Urol 2020 May-Jun;46(3):425-433

Department of Urology, University of Health Sciences, Istanbul Bakirkoy Dr. Sadi Konuk Training and Research Hospital, Istanbul, Turkey.

Objective: Minimally invasive techniques are used increasingly by virtue of advancements in technology. Surgery for prostate cancer, which has high morbidity, is performed with an increasing momentum based on the successful oncological and functional outcomes as well as cosmetic aspects.

Materials And Methods: 62 patients underwent robot-assisted perineal radical prostatectomy (R-PRP) surgery at our clinic between November 2016 and August 2017. Read More

Nat Rev Urol 2020 03 21;17(3):177-188. Epub 2020 Feb 21.

Department of Urology, Royal Melbourne Hospital, University of Melbourne, Melbourne, Australia.

The practice of radical prostatectomy for treating prostate cancer has evolved remarkably since its general introduction around 1900. Initially described using a perineal approach, the procedure was later popularized using a retropubic one, after it was first described as such in 1948. The open surgical method has now largely been abandoned in favour of the minimally invasive robot-assisted method, which was first described in 2000. Read More

Urologe A 2020 Apr;59(4):398-407

Klinik für Urologie, Asklepios Klinik Barmbek, Rübenkamp 220, 22307, Hamburg, Deutschland.

Bladder neck stenosis (BNS) after simple prostatectomy and vesicourethral anastomosis stenosis (VUAS) after radical prostatectomy for prostate cancer are common sequelae. However, the two entities differ in their pathology, anatomy and their surgical results. VUAS has an incidence of 0. Read More

Aktuelle Urol 2020 Jan 28. Epub 2020 Jan 28.

Bakirkoy Dr. Sadi Konuk Training and Research Hospital, Department of Urology, Istanbul.

Radical prostatectomy (RP) is the primary and standard treatment for localized prostate cancer. As in many surgical procedures, RP can now be accomplished through minimally invasive methods. RP in a patient with a pre-existing 3-piece inflatable penile prosthesis (IPP) is an exceptional condition and involves coping with many difficulties. Read More

BJU Int 2020 04 21;125(4):573-578. Epub 2020 Feb 21.

Department of Urology, Istanbul Bakirkoy Dr Sadi Konuk Training and Research Hospital, University of Health Sciences, Istanbul, Turkey.

Objectives: To assess the early functional and oncological outcomes of a large series of patients who underwent robot-assisted radical perineal prostatectomy (RPP).

Materials And Methods: We retrospectively analysed the patients who underwent robot-assisted RPP for localized prostate cancer between November 2016 and September 2018. Patients who had locally advanced disease proven on biopsy or were suspected to have locally advanced disease on multiparametric magnetic resonance imaging and patients who had a contraindication for the exaggerated lithotomy position were not included in this study. Read More

World J Urol 2020 Apr 6;38(4):821-828. Epub 2019 Dec 6.

Glickman Urology and Kidney Institute, Cleveland Clinic, 9500 Euclid Avenue, Q10, Cleveland, OH, 44195, USA.

Purpose: To review the recent advances in terms of surgical technique and new robotic platforms applied to radical perineal prostatectomy (RPP).

Methods: A literature review was performed focusing on original articles on perineal prostatectomy searching via Medline/Pubmed and Embase. The entire spectrum was covered such as development of surgical technique including pelvic lymphadenectomy, adoption of novel surgical platforms, learning curve and future directions. Read More

Asian J Urol 2019 Oct 21;6(4):364-367. Epub 2018 Jun 21.

Department of Neurourology, Tenon Hospital, GRC01 GREEN Group de Recherche Clinical Neurourology, Sorbonne University UPMC, Paris, France.

Objective: Prostate cancer is the most frequent cancer in men and radical retropubic prostatectomy (RRP) is one of the first-line treatment. However, RRP has some side effects and can lead to chronic perineal pain. The objective of the study was to determine in patients suffering from perineal pain after RRP the possibility of a neurogenic damage by means of a specific questionnaire dedicated to track down neuropathic pain. Read More

Urology 2020 Feb 24;136:257-262. Epub 2019 Oct 24.

Hospital Universitário Pedro Ernesto-State University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil.

Objective: To compare ultrasonographic patterns of 2-dimensional perineal ultrasonography in men in the preoperative and postoperative periods after transobturator sling deployment for the treatment of urinary incontinence after radical prostatectomy. Radiotherapy and radical prostatectomy are the primary treatments for localized prostate cancer. Studies comparing anatomic changes in men before and after radical prostatectomy based on perineal ultrasonography are scarce in the literature. Read More

Front Oncol 2019 9;9:758. Epub 2019 Aug 9.

Department of Urology, Shanghai Changhai Hospital, Second Military Medical University, Shanghai, China.

The present study aimed to investigate the diagnostic efficacy and the regional location of prostate cancer (PCa) as well as the accuracy of assessment between trans-perineal template-guided mapping biopsy (TTMB) and freehand trans-perineal biopsy (FTPB) for men with PSA < 20 ng/ml. Thus, we evaluated 623 consecutive patients with PSA < 20 ng/ml who had prostate biopsies in our institute between July 2017 and September 2018. Patients were divided into two groups based on different biopsy methods: 217 (34. Read More

Turk J Urol 2019 07 3;45(4):265-272. Epub 2019 Apr 3.

Department of Urology, Health Sciences University, Bakırköy Dr. Sadi Konuk Training and Research Hospital, İstanbul, Turkey.

Objective: We compared the outcomes of robotic-assisted radical perineal prostatectomy (r-PRP) versus robotic-assisted transperitoneal laparoscopic radical prostatectomy (RARP).

Material And Methods: Between November 2016 and September 2017 in our center, 40 patients underwent r-PRP, and 40 patients underwent RARP. All patients also underwent multiparametric magnetic resonance imaging (mpMRI) to exclude the cases with locally advanced disease. Read More