4,201 results match your criteria Proctitis and Anusitis
Arq Gastroenterol 2018 Jul-Sep;55(3):290-295
Universidade do Estado da Bahia, Departamento de Ciências da Vida, Salvador, BA, Brasil.
Background: The diagnosis of inflammatory bowel disease is often delayed because of the lack of an ability to recognize its major clinical manifestations.
Objective: Our study aimed to describe the onset of clinical manifestations in inflammatory bowel disease patients.
Methods: A cross-sectional study. Read More
Sex Transm Dis 2018 Dec 3. Epub 2018 Dec 3.
Division of Infectious Diseases, Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles.
The incidence of syphilis is increasing. Syphilitic proctitis involving the rectal mucosa often presents with pain on defecation, rectal bleeding, or ulceration. We present a case of asymptomatic syphilitic proctitis diagnosed upon a routine screening colonoscopy. Read More
Eur J Gastroenterol Hepatol 2018 Nov 29. Epub 2018 Nov 29.
Nottingham Digestive Diseases Centre.
Background: Mesalazine-refractory ulcerative proctitis is common, with a significant proportion of the patients requiring escalation to immunomodulators or biological therapy. Three small preliminary cohort studies suggested good clinical efficacy for the organic arsenic derivative acetarsol in the management of proctitis. Our aim was to describe our experience on the use of acetarsol in proctitis and to review all existing evidence on its safety and efficacy. Read More
JGH Open 2018 Aug 6;2(4):129-133. Epub 2018 Jun 6.
Gastroenterology and Hepatology Unit Teaching Hospital Kandy Kandy Sri Lanka.
Background And Aim: There is increasing prevalence of inflammatory bowel disease (IBD) in Asia, but Sri Lankan data on the state of epidemiology and clinical course of IBD are scarce.
Methods: A hospital-based study was done by recruiting IBD patients who permanently reside in the Central Province (population 2.57 million, 12. Read More
Eur Rev Med Pharmacol Sci 2018 Nov;22(21):7562-7572
Radiotherapy Oncology Center, Azienda Ospedaliera of Cosenza, Cosenza, Italy.
Objective: The main limit of radiation therapy is the dose-dependent toxicity to healthy tissues. The 36% of patients exposed to radiotherapy for pelvic malignancies reporting gastrointestinal symptoms as incontinence, pain, mucus discharge, and bleeding (radiation proctopathy). In the cervix cancer, healthy tissues exposed to radiations easily develop inflammation of vaginal mucosa, bleeding and pain and to improve these symptoms, some medical devices were developed. Read More
Phytother Res 2018 Nov 14. Epub 2018 Nov 14.
Urology and Nephrology Research Center, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Clinical potential of curcumin in radiotherapy (RT) setting is outstanding and of high interest. The main purpose of this randomized controlled trial (RCT) was to assess the beneficial role of nanocurcumin to prevent and/or mitigate radiation-induced proctitis in prostate cancer patients undergoing RT. In this parallel-group study, 64 eligible patients with prostate cancer were randomized to receive either oral nanocurcumin (120 mg/day) or placebo 3 days before and during the RT course. Read More
Nutrients 2018 Nov 12;10(11). Epub 2018 Nov 12.
Department of Rheumatology and Clinical Immunology, Faculty of Medicine, School of Health Sciences, University of Thessaly, Biopolis, GR41110 Larissa, Greece.
Curcumin has demonstrated anti-inflammatory properties and has been investigated as an adjuvant therapy of ulcerative colitis (UC). The scope of this study was to systematically review and meta-analyze the efficacy of oral curcumin administration as an adjuvant therapy of UC. MEDLINE, Cochrane/CENTRAL, ClinicalTrials. Read More
Asian Pac J Cancer Prev 2018 Oct 26;19(10):2745-2750. Epub 2018 Oct 26.
Radiation Oncology Research Center, Department of Radiation Oncology, Cancer Institute, Tehran University of Medical Sciences, Tehran, Iran. Email:
Objective: Cervical carcinoma is the third most common gynecologic cancer, after ovarian and uterine cancers in Iran. The aim of this study was to evaluate the efficacy (response rate) and toxicity of adding Medium Dose Rate (MDR) brachytherapy with concurrent chemotherapy to External Beam Radiotherapy (EBRT) for the treatment of locally advanced uterine cervical carcinoma. Methods: This phase I-II study was conducted in 2007-2008 at the cancer institute, Tehran University of Medical Sciences. Read More
Scand J Gastroenterol 2018 Oct 23:1-5. Epub 2018 Oct 23.
a Digestive Disease Department , General University Hospital of Valencia , Valencia , Spain.
Introduction: Ulcerative proctitis is a type of ulcerative colitis circumscribed to the rectum. Proximal progression rates of the disease have been reported as between 27% and 54%. Several predictive factors have been identified for its progression; however, none has been established as definitive. Read More
Acta Gastroenterol Belg 2018 Jul-Sep;81(3):430-432
Department of Gastroenterology, University Hospital Gasthuisberg, Leuven, Belgium.
Rectal ulcerations are an uncommon presentation of a primary syphilis infection. Anorectal syphilis is difficult to diagnose because of its often asymptomatic or atypical clinical presentation. It is important to consider sexually transmitted diseases (STD) in all patients presenting with rectal symptoms. Read More
Intern Med 2018 Oct 17. Epub 2018 Oct 17.
Department of Gastroenterology and Metabolism, Hiroshima University Hospital, Japan.
Objective Rectal lymphoid follicular aphthous (LFA) lesions are related to ulcerative colitis (UC) and can be initial lesions of UC. We investigated the clinical course and prognosis of rectal LFA lesions. Methods This is a retrospective analysis of the clinical records at a single center. Read More
Intest Res 2018 Oct 10;16(4):554-562. Epub 2018 Oct 10.
Department of Medicine, Shiga University of Medical Science, Otsu, Japan.
Background/aims: Noninvasive objective monitoring is advantageous for optimizing treatment strategies in patients inflammatory bowel disease (IBD). Fecal calprotectin (FCP) is superior to traditional biomarkers in terms of assessing the activity in patients with IBD. However, there are the differences among several FCP assays in the dynamics of FCP. Read More
Pediatr Dev Pathol 2018 Oct 4:1093526618803770. Epub 2018 Oct 4.
3 Department of Pediatrics, Division of gastroenterology, Children's Hospital of Eastern Ontario Research Institute, Ottawa, Canada.
Cow's milk protein allergy/intolerance (CMPA/CMPI) is a common entity in the pediatric population with a nonspecific presentation ranging from gastrointestinal symptoms to systemic manifestations. Most infants with CMPI are term, and symptoms often appear in the week following the introduction of cow's milk-based formula. There is typically a significant delay in the onset of milk allergy in premature infants compared to full term. Read More
Anticancer Res 2018 Oct;38(10):5959-5962
Department of Radiology, National Defense Medical College, Saitama, Japan.
Background/aim: To examine whether CT-guided daily adaptive radiation therapy (ART) can be safely administered against localized prostate cancer.
Patients And Methods: Twenty-six patients with localized prostate adenocarcinoma were irradiated through opposed AP/PA fields up to 46 Gy, then CT-guided daily ART was performed through opposed lateral fields until 76 Gy at 2 Gy/fraction.
Results: Biochemical relapse-free survival was 89% at 3 years and 85% at 5 years and 76% at 7 years after ART, respectively. Read More
World J Gastroenterol 2018 Sep;24(36):4186-4196
Division of Gastroenterology, Department of Internal Medicine, Faculty of Medicine, Dokuz Eylül University, İzmir 35360, Turkey.
Aim: To specify the type and prevalence of anemia along with a treatment approach for inflammatory bowel disease (IBD).
Methods: We conducted a retrospective study on 465 patients who were diagnosed with IBD and followed up at our hospital from June 2015 to June 2016 [male: 254, female: 211; average age: 47 ± 14.4; Crohn's disease (CD): 257, Ulcerative Colitis (UC): 208]. Read More
Dermatol Online J 2018 Jul 15;24(7). Epub 2018 Jul 15.
Naval Medical Center, San Diego, California.
Linear IgA bullous dermatosis is a rare bullous disease in children and adults that can be associated with autoimmune conditions, malignancies, infections, or medication exposure. The definitive diagnosis relies on the biopsy. A 58-year-old man presented to our clinic with a pruritic vesicular and bullous eruption. Read More
Jpn J Clin Oncol 2018 Nov;48(11):988-994
Department of Radiation Oncology, Yonsei University College of Medicine, Seoul.
Objectives: High-dose pelvic radiotherapy (RT) is known to be associated with chronic radiation proctitis (RP). However, the effects of intermediate radiation doses are unknown. We assessed the incidence of late clinical RP among patients with rectal cancer receiving intermediate-dose postoperative RT, as well as the role of early endoscopic abnormalities in predicting RP development. Read More
Clin J Gastroenterol 2018 Sep 20. Epub 2018 Sep 20.
Department of Pathology, Nikko Medical Center, Dokkyo Medical University, Tochigi, Japan.
Solitary extramedullary plasmacytoma (EMP) arising in the rectum is an extremely rare clinical entity. Only ten cases have been reported in the English-language literature. We experienced a case of an EMP in the rectum of a 55-year-old man with an 8-year history of proctitis-type ulcerative colitis (UC). Read More
Aliment Pharmacol Ther 2018 Nov 18;48(9):941-950. Epub 2018 Sep 18.
Background: Treatment paradigms for Crohn's disease with perianal fistulae (CD-pAF) are evolving.
Aims: To study the impact of multimodality treatment in CD-pAF on recurrence rates and the need for re-interventions and to identify predictive factors for these outcomes.
Methods: This was a multinational multicentre retrospective cohort study. Read More
Adv Radiat Oncol 2018 Jul-Sep;3(3):339-345. Epub 2018 May 8.
Department of Radiation and Cellular Oncology, The University of Chicago, Chicago, Illinois.
Purpose: Dose-volume histogram (DVH) toxicity relationships are poorly defined in men who receive radiation after radical prostatectomy (RP). We evaluated Radiation Therapy Oncology Group (RTOG) study 0534 and institutional intact normal-tissue sparing guidelines, as well as dose to bladder trigone, for ability to minimize late toxicity.
Methods And Materials: 164 men received intensity modulated radiation therapy (RT) to a median prostate bed dose of 66. Read More
Dis Colon Rectum 2018 Oct;61(10):1135-1140
Cleveland Clinic, Cleveland, Ohio.
Strahlenther Onkol 2018 Sep 6. Epub 2018 Sep 6.
Department of Radiotherapy and Special Oncology, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany.
Purpose: To compare relative and absolute dose-volume parameters (DV) of the rectum and their clinical correlation with acute and late radiation proctitis (RP) after radiotherapy (RT) for prostate cancer (PCa).
Patients And Methods: 366 patients received RT for PCa. In total, 49. Read More
Exp Ther Med 2018 Sep 18;16(3):2319-2324. Epub 2018 Jul 18.
Department of Gastroenterology, The Second Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi 530007, P.R. China.
The aim of the present study was to investigate the safety and efficacy of mesalazine suppository in the treatment of refractory ulcerative chronic radiation proctitis (CRP). In total, 10 refractory ulcerative CRP patients who did not respond to previous medical treatments were recruited for the present study and were treated with mesalazine suppository (0.5 g) twice daily for 24 weeks. Read More
Strahlenther Onkol 2018 Sep 4. Epub 2018 Sep 4.
Department of Radiation Oncology, Klinikum rechts der Isar, Technical University of Munich (TUM), Ismaninger Straße 22, 81675, Munich, Germany.
Purpose: The present study aims to evaluate both early and late toxicity profiles of patients receiving immediate postoperative radiotherapy (RT; adjuvant RT or additive RT) compared to salvage RT.
Methods: We evaluated 253 patients with prostate cancer treated with either immediate postoperative (adjuvant RT, n = 42; additive RT, n = 39) or salvage RT (n = 137). Thirty-five patients received salvage treatment but did not achieve a postoperative prostate specific antigen (PSA) level <0. Read More
J Coll Physicians Surg Pak 2018 Sep;28(9):S162-S163
Department of Radiology, Shifa International Hospital, Islamabad.
Colitis cystica profunda (CCP) is a rare benign disease characterised by mucin-filled cysts beneath the muscularis mucosae, which commonly involves the rectum and sigmoid colon. The disease process involving rectum is termed as proctitis cystica profunda. Trans-rectal ultrasound (TRUS) and magnetic resonance imaging (MRI) are an aid to diagnosis. Read More
Radiat Oncol 2018 Aug 29;13(1):162. Epub 2018 Aug 29.
Department of Radiation Oncology, Sir Charles Gairdner Hospital, Perth, Western Australia.
Background: Although patients experience radiation proctitis post radiotherapy no internationally tested instruments exist to measure these symptoms. This Phase IV study tested the scale structure, reliability and validity and cross-cultural applicability of the EORTC proctitis module (QLQ-PRT23) in patients who were receiving pelvic radiotherapy.
Methods: Patients (n = 358) from six countries completed the EORTC QLQ-C30, QLQ-PRT23 and EORTC Quality of Life Group debriefing questions. Read More
Int J Infect Dis 2018 Oct 17;75:34-38. Epub 2018 Aug 17.
Infectious Disease Unit, Sheba Medical Center, Ramat Gan, Israel; Sackler Medical School, Tel Aviv University, Tel Aviv, Israel.
Objective: Sexually transmitted diseases (STDs), mainly lymphogranuloma venereum (LGV), induce colorectal symptoms that may be misdiagnosed as inflammatory bowel disease (IBD). This study describes patients who presented with STDs masquerading as IBD in order to improve understanding of missed diagnosis of colorectal STDs and their association with LGV in Israel.
Methods: This retrospective, descriptive study characterized the clinical, endoscopic, and pathological findings of 16 patients who were diagnosed with a colorectal STD after erroneously being diagnosed with IBD. Read More
Int J Radiat Oncol Biol Phys 2018 Aug 17. Epub 2018 Aug 17.
Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, USA. Electronic address:
Purpose: The aim of this study was to systematically review tolerance doses for late distinct gastrointestinal, genitourinary, and sexual dysfunction (GI/GU/SD) symptoms following external-beam RT (EBRT) alone and treatments involving brachytherapy (BT±EBRT) for prostate cancer post-QUANTEC, and to ultimately perform quantitative syntheses of identified dose/volume tolerances represented by dose-volume histogram (DVH) thresholds, i.e., statistically significant (p≤0. Read More
Int J STD AIDS 2018 Aug 16:956462418788418. Epub 2018 Aug 16.
1 Anova Health Institute, Johannesburg, South Africa.
This study from South Africa highlights the importance of rectal Trichomonas vaginalis infection as a sexually transmitted infection among men who have sex with men (MSM). We report seven MSM presenting with rectal T. vaginalis infection. Read More
Endosc Int Open 2018 Aug 10;6(8):E1059-E1064. Epub 2018 Aug 10.
Gastrointestinal Diseases Research Unit (GIDRU), Department of Medicine, Queen's University, Kingston ON, Canada.
Background And Aims: Rectal bleeding affects ~15 % of the general population and is a common reason for referral to gastroenterologists by primary care physicians. Direct to procedure flexible sigmoidoscopy is an appealing modality to investigate rectal bleeding due its diagnostic yield, safety profile, and accessibility. Patients referred on a routine basis for direct to procedure clinic by primary care physicians with the sole complaint of rectal bleeding have not previously been studied. Read More
Clin Oncol (R Coll Radiol) 2018 Sep 30;30(9):534-538. Epub 2018 Jun 30.
Sussex Cancer Centre, Brighton & Sussex University Hospitals NHS Trust, Brighton, UK.
Aims: Inflammatory bowel disease (IBD) has historically been considered a risk factor for increased bowel toxicity in patients receiving pelvic external beam radiotherapy. The risk is reduced in intensity-modulated radiotherapy compared with three-dimensional conformal radiotherapy. The effect of brachytherapy has been less extensively researched. Read More
J Glob Oncol 2018 Jul(4):1-9
All authors: Tata Memorial Centre, Navi Mumbai, India.
Purpose Recent guidelines recommend magnetic resonance imaging-based brachytherapy (MRBT) for locally advanced cervical cancer. However, its implementation is challenging within the developing world. This article reports the outcomes of patients with locally advanced cervical cancer treated with chemoradiation and point A-based brachytherapy (BT) using x-ray- or computed tomography-based planning. Read More
Inflamm Bowel Dis 2018 Aug 1. Epub 2018 Aug 1.
Department of Gastroenterology and Hepatology, University Medical Center Utrecht, Utrecht, the Netherlands.
Background: Patients with refractory inflammatory bowel disease (IBD) might require a subtotal colectomy with construction of an ileostomy. Due to the risk of nerve damage and pelvic sepsis, the diverted rectum is often left in situ. Evidence on long-term complications of this rectal stump is limited, particularly in patients with Crohn's disease (CD). Read More
Clin Gastroenterol Hepatol 2018 Aug 3. Epub 2018 Aug 3.
Gastroenterology Department, Amiens University Hospital, Amiens, France.
Future Oncol 2018 Aug 3;14(19):1977-1988. Epub 2018 Aug 3.
Division of Respiratory Medicine, Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya, Hyogo, Japan.
Chemoradiotherapy is important for treating malignancies. However, radiation-induced toxicities develop as chemoradiotherapy-related complications. Various agents reduce or prevent toxicities, but there are no standard treatments. Read More
Am Surg 2018 Jul;84(7):1175-1179
Patients presenting with near-obstructing colon lesions requiring segmental colectomy may benefit from intraoperative colonoscopy (IOC) after primary anastomosis for a more timely and accurate diagnosis of synchronous lesions. The aim of this study is to demonstrate the feasibility and safety of this technique. A retrospective cohort study of patients undergoing single-stage segmental colectomy and anastomosis at a single tertiary care institution from 2011 to 2013 was performed. Read More
Best Pract Res Clin Gastroenterol 2018 Feb - Apr;32-33:49-57. Epub 2018 May 18.
Department of Gastroenterology, Saint-Eloi Hospital, Montpellier University Hospital, Montpellier University, Montpellier, France.
Ulcerative proctitis is defined as a mucosal inflammation limited to the rectum. Ulcerative proctitis is responsible for distressing symptoms and alteration of patient quality of life. Effective treatment is important to prevent or delay proximal extension of the disease and to improve quality of life. Read More
Zhonghua Wei Chang Wai Ke Za Zhi 2018 Jul;21(7):772-778
Department of General Surgery, Jinling Hospital, Nanjing 210002, China.
Objective: To summarize the application of staged ileostomy and closure operation combined with nutritional support therapy in the treatment of chronic radiation intestinal injury(CRII).
Methods: Clinical data of patients with definite radiation history and pathological diagnosis of CRII receiving treatment at Department of General Surgery, Jinling Hospital from January 2012 to December 2016 were retrospectively analyzed. Patients who were diagnosed with tumor recurrence during operation or by postoperative pathology were excluded. Read More
Case Rep Gastroenterol 2018 May-Aug;12(2):254-259. Epub 2018 Jun 15.
Division of Gastroenterology and Hepatology, Department of Internal Medicine, Faculty of Medicine, Prince of Songkla University, Hat Yai, Thailand.
Phlegmonous proctitis is a rare condition; it was first described in 1940. We report the case of an elderly woman who presented with acute severe lower abdominal pain, tenesmus, and fever. A computed tomography of the whole abdomen revealed a long segment of circumferential wall thickening of the rectum and rectosigmoid colon. Read More
Paediatr Int Child Health 2018 Jul 17:1-9. Epub 2018 Jul 17.
a Department of Pediatrics, Faculty of Medicine , Mahidol University , Bangkok , Thailand.
The prevalence of food allergy and food intolerance is increasing and it is an important public health problem affecting children. Food allergy results from an immunological reaction to certain food(s) and affects numerous organs in the body. Food intolerances are non-immunological reactions including metabolic, toxic, pharmacological and undefined mechanisms. Read More
Int J Radiat Oncol Biol Phys 2018 Aug 5;101(5):1194-1201. Epub 2018 May 5.
Duke University School of Medicine, Department of Radiation Oncology, Durham, North Carolina. Electronic address:
Purpose: Radiotherapy (RT) is commonly used to treat most pelvic malignancies. While treatment is often effective, curative radiation doses to the rectum can result in chronic radiation-induced proctitis, which is characterized by diarrhea, tenesmus, and/or rectal bleeding, recently termed pelvic radiation disease. An animal model of chronic radiation-induced proctitis would be useful to test both preventative and therapeutic strategies to limit this morbidity but has been elusive because of the high rodent mortality associated with acute bowel RT injury. Read More
Perm J 2018 06;22
Gastroenterologist at Nakadori General Hospital in Japan.
Context: No known published study has focused on a plant-based diet (PBD) in the treatment of ulcerative colitis (UC).
Objective: To investigate relapse prevention in UC after consumption of a PBD during educational hospitalization in Japan.
Design: Prospective study of patients with mild UC or UC in remission who did not need immediate treatment. Read More
Int J Radiat Oncol Biol Phys 2018 Jul 11;101(4):957-963. Epub 2018 Apr 11.
The University of Manchester and Christie NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, United Kingdom.
Purpose: To test the hypothesis that increased acute toxicity, measured using subdomains reflective of epithelial cell damage, will be associated with reduced late biochemical failure, as a surrogate for tumor radiosensitivity.
Methods And Materials: The study design was retrospective, with discovery and validation cohorts involving routinely collected data. Eligible patients had prostate cancer, underwent radiation therapy with curative intent, and had acute toxicity assessed prospectively. Read More
Dig Dis Sci 2018 Sep;63(9):2180-2188
Department of Colon and Rectal Surgery, Digestive Disease Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates.
Radiation proctitis is radiation-induced rectal mucositis, occurring as a result of radiation therapy for various pelvic malignancies. The management of radiation proctitis is challenging as guidelines are not currently available, and studies of the various treatment modalities are limited. There are various medical, endoscopic, and surgical measures for treating chronic radiation proctitis. Read More
Radiat Oncol 2018 Jun 25;13(1):119. Epub 2018 Jun 25.
National Institute of Radiological Sciences Hospital, National Institutes for Quantum and Radiological Science and Technology, 4-9-1 Anagawa, Inage-ku, Chiba, 263-8555, Japan.
Background: Carbon-ion radiotherapy (C-ion RT) provides better dose distribution in cancer treatment compared to photons. Additionally, carbon-ion beams provide a higher biological effectiveness, and thus a higher tumor control probability. However, information regarding the dose constraints for organs at risk in C-ion RT is limited. Read More
Medicina (B Aires) 2018 ;78(3):207-210
Cátedra de Microbiología Clínica, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Argentina.
From 2003 to date there has been a rising number of reports from developed countries on cases of lymphogranuloma venereum with anorectal localization in HIV-infected men who have sex with men. This localization differs from the classical inguinal abscesses which are typical of the disease in the tropics. The objective of this work is to document the presence of anorectal lymphogranuloma venereum in Buenos Aires and to describe its varied clinical manifestations. Read More
Rev Esp Enferm Dig 2018 Sep;110(9):591-593
Zhujiang Hospital, Southern Medical University.
Lymphoid follicular proctitis (LFP) is an uncommon inflammatory disease that is characterized by rectal bleeding, congested and granular mucosa without ulceration and abnormal and coalescing hyperplastic lymphoid follicles without acute inflammatory changes. The lesions are usually confined to the rectal mucosa. LFP therapy is not well defined. Read More