4,251 results match your criteria Proctitis


Herpes Simplex Virus Proctitis Masquerading as Rectal Cancer.

Diseases 2019 Apr 21;7(2). Epub 2019 Apr 21.

Department of Pathology and Laboratory Medicine, Miller School of Medicine, University of Miami, Miami, FL 33136, USA.

Herpes simplex virus (HSV) is the leading cause of proctitis in HIV-infected individuals. However, no cases of rectal masses secondary to HSV infection have been reported to date. Herein, we present the case of a 45-year-old man with HIV infection who developed rectal pain and bleeding, along with dysuria and voiding difficulty. Read More

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http://dx.doi.org/10.3390/diseases7020036DOI Listing

The use of aloe vera in cancer radiation: An updated comprehensive review.

Complement Ther Clin Pract 2019 May 31;35:126-130. Epub 2019 Jan 31.

St. John Fisher College Wegmans School of Pharmacy, 3690 East Avenue, Rochester, NY, 14618, USA.

Introduction: Many cancer patients require radiation therapy and often experience adverse effects including erythema, itching, and pain. Aloe vera has been studied for its potential use in the prevention and treatment of radiation related adverse effects as it possesses a variety of properties and is considered an antioxidant and anti-inflammatory agent. Multiple controlled trials have been performed in order to evaluate the efficacy of aloe vera for the prevention and treatment of radiation side effects. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S17443881183051
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http://dx.doi.org/10.1016/j.ctcp.2019.01.013DOI Listing
May 2019
2 Reads

A 30-year trend analysis in the epidemiology of inflammatory bowel disease in the Songpa-Kangdong District of Seoul, Korea in 1986-2015.

J Crohns Colitis 2019 Apr 16. Epub 2019 Apr 16.

Department of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

Background And Aims: Although the incidence of inflammatory bowel disease (IBD) is increasing in Asia, data on long-term epidemiologic trends are limited. We performed a 30-year longitudinal study to investigate temporal trends in the epidemiology of Crohn's disease (CD) and ulcerative colitis (UC) in Seoul, Korea.

Methods: This population-based study included 1431 IBD patients (418 CD, 1013 UC) diagnosed between 1986 and 2015 in the Songpa-Kangdong district of Seoul, Korea. Read More

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http://dx.doi.org/10.1093/ecco-jcc/jjz081DOI Listing
April 2019
1 Read

Colitis cystica profunda of the rectum with adenomatous dysplastic features: Radiologic-pathologic correlation.

Radiol Case Rep 2019 Jun 3;14(6):740-745. Epub 2019 Apr 3.

Radiology Department, Fondazione di Ricerca e Cura "Giovanni Paolo II", Campobasso 86100, Italy.

Colitis cystica profunda is a rare nonneoplastic condition characterized by the presence of mucus-containing cysts in the submucosa of the right colon and rectum. The etiology is unclear, with a few cases reported in the literature. The presenting symptoms and signs may mimic colorectal adenocarcinoma. Read More

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http://dx.doi.org/10.1016/j.radcr.2019.03.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447733PMC
June 2019
2 Reads

Efficacy and complications of argon plasma coagulation for hemorrhagic chronic radiation proctitis.

World J Gastroenterol 2019 Apr;25(13):1618-1627

Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, Sun Yat-sen University, Guangzhou 510655, Guangdong Province, China.

Background: Chronic radiation proctitis (CRP) is a complication which occurs in 1%-5% of patients who undergo radiotherapy for pelvic malignancies. Although a wide range of therapeutic modalities are available, there is no literature to date showing any particularly appropriate therapeutic modality for each disease stage. Argon plasma coagulation (APC) is currently recommended as the first-choice treatment for hemorrhagic CRP, however, its indication based on long-term follow-up is still unclear. Read More

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http://dx.doi.org/10.3748/wjg.v25.i13.1618DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6452229PMC

Management of Severe Radiation Proctitis with Radiofrequency Ablation.

GE Port J Gastroenterol 2019 Mar 22;26(2):128-130. Epub 2018 Mar 22.

Department of Gastroenterology, Instituto Português de Oncologia de Lisboa Francisco Gentil, Lisbon, Portugal.

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http://dx.doi.org/10.1159/000487447DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454389PMC

Saponins regulate intestinal inflammation in colon cancer and IBD.

Pharmacol Res 2019 Apr 5;144:66-72. Epub 2019 Apr 5.

Dalian Medical University, Dalian 116044, China. Electronic address:

The saponins are natural surface-active glycosides which are the principal components of many popular herbal medicinal plants such as ginseng, astragalus, and bupleurum. Recent studies have suggested that saponins can exert strong anti-inflammatory effects and induce immune homeostasis in many diseases. Intestinal-inflammation-related digestive diseases include inflammatory bowel disease (IBD), irritable bowel syndrome, intestinal ischemia-reperfusion injury, necrotizing enterocolitis and radiation proctitis, as well as intestinal inflammation caused by nonsteroidal anti-inflammatory drugs. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10436618183196
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http://dx.doi.org/10.1016/j.phrs.2019.04.010DOI Listing
April 2019
3 Reads
4.408 Impact Factor

Predictive factors for response and toxicity after brachytherapy for rectal cancer; results from the HERBERT study.

Radiother Oncol 2019 Apr 18;133:176-182. Epub 2019 Feb 18.

Leiden University Medical Center LUM, Department of Radiation Oncology, the Netherlands.

Purpose: The HERBERT study was a dose-finding feasibility study of a high-dose rate endorectal brachytherapy (HDREBT) boost after external beam radiotherapy (EBRT) in elderly patients with rectal cancer who were unfit for surgery. This analysis evaluates the association of patient, tumor and dosimetric parameters with tumor response and toxicity after HDREBT in definitive radiotherapy for rectal cancer.

Patients And Methods: The HERBERT study included 38 inoperable patients with T2-3N0-1 rectal cancer. Read More

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http://dx.doi.org/10.1016/j.radonc.2019.01.034DOI Listing
April 2019
1 Read

Bacterial sexually transmitted infections.

J Dtsch Dermatol Ges 2019 Mar;17(3):287-315

WIR "Walk In Ruhr", competence network HIV/AIDS, Center for Sexual Health and Medicine, Department of Dermatology, Venereology and Allergology, Ruhr University, Bochum, Germany.

Worldwide, the incidence of bacterial sexually transmitted infections (STIs) has shown a significant increase in recent years. In Germany, this circumstance is reflected by a rise in the number of reported syphilis cases. There has also been an uptick in the incidence of non-notifiable STIs such as gonorrhea and infections caused by Chlamydia trachomatis and Mycoplasma genitalium. Read More

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http://dx.doi.org/10.1111/ddg.13804DOI Listing
March 2019
2 Reads

[Rectal bleeding: easy to overcome or still a challenge in proctology?]

Authors:
O Schwandner O Pech

Chirurg 2019 Mar 25. Epub 2019 Mar 25.

Klinik für Gastroenterologie und interventionelle Endoskopie, Krankenhaus Barmherzige Brüder Regensburg, Regensburg, Deutschland.

Rectal bleeding is a frequent symptom in proctology. In most cases frequent causes, such as anal fissures and hemorrhoidal disease can be diagnosed and treated using a structured patient history and basic proctological diagnostic assessment; however, it is not uncommon for proctitis to be the reason for rectal bleeding, which necessitates interdisciplinary diagnostics and treatment. In addition to proctitis associated with chronic inflammatory bowel disease, prolapse-induced, radiogenic, ischemic, infectious types and proctitis associated with sexually transmitted diseases represent important differential diagnoses. Read More

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http://dx.doi.org/10.1007/s00104-019-0944-yDOI Listing
March 2019
1 Read

Evaluation of Rectal Vancomycin Irrigation for Treatment of Clostridioides difficile Infection in Patients Post-Colectomy for Toxic Colitis.

Surg Infect (Larchmt) 2019 Mar 22. Epub 2019 Mar 22.

2 Department of Pharmacy, The Ohio State University Wexner Medical Center, Columbus, Ohio.

Background: Clostridioides difficile infection (CDI) accounts for as many as 25% of episodes of antibiotic-associated diarrhea and is the most common cause of healthcare-associated diarrhea. Rectal vancomycin irrigation is a therapy option; however, evidence is limited for its value post-colectomy. The objective of this study was to describe outcomes of patients who underwent total colectomy for fulminant C. Read More

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http://dx.doi.org/10.1089/sur.2018.265DOI Listing

Stromal Fibroblasts Drive Host Inflammatory Responses That Are Dependent on Chlamydia trachomatis Strain Type and Likely Influence Disease Outcomes.

MBio 2019 03 19;10(2). Epub 2019 Mar 19.

Center for Immunobiology and Vaccine Development, UCSF Benioff Children's Hospital Oakland Research Institute, Oakland, California, USA

ocular strains cause a blinding disease known as trachoma. These strains rarely cause urogenital infections and are not found in the upper genital tract or rectum. Urogenital strains are responsible for a self-limited conjunctivitis and the sequelae of infertility, ectopic pregnancy, and hemorrhagic proctitis. Read More

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http://dx.doi.org/10.1128/mBio.00225-19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426598PMC
March 2019
2 Reads

Symptoms, Sites, and Significance of Mycoplasma genitalium in Men Who Have Sex with Men.

Emerg Infect Dis 2019 Apr;25(4):719-727

During 2016-2017, we tested asymptomatic men who have sex with men (MSM) in Melbourne, Australia, for Mycoplasma genitalium and macrolide resistance mutations in urine and anorectal swab specimens by using PCR. We compared M. genitalium detection rates for those asymptomatic men to those for MSM with proctitis and nongonococcal urethritis (NGU) over the same period. Read More

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http://dx.doi.org/10.3201/eid2504.181258DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433010PMC
April 2019
2 Reads

Four percent formalin application for the management of radiation proctitis in carcinoma cervix patients: An effective, safe, and economical practice.

J Cancer Res Ther 2019 Jan-Mar;15(1):92-95

Department of Radiotherapy, IGMC, Shimla, Himachal Pradesh, India.

Context: Radiotherapy is a very effective treatment modality for pelvic malignancies such as carcinoma of the cervix. However, it is quite common for chronic radiation proctitis (CRP) to manifest after radical radiotherapy. CRP is a source of significant morbidity, and there is a lack of effective treatment modalities. Read More

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http://dx.doi.org/10.4103/jcrt.JCRT_393_17DOI Listing
March 2019
4 Reads

Infections caused by Chlamydia trachomatis (including lymphogranuloma venereum) and Mycoplasma genitalium.

Enferm Infecc Microbiol Clin 2019 Mar 13. Epub 2019 Mar 13.

Unidad de ITS Vall d'Hebron-Drassanes, Servicio de Enfermedades Infecciosas, Hospital Vall d'Hebron, Barcelona, España.

Sexually transmitted infections caused by Chlamydia trachomatis, including lymphogranuloma venereum and Mycoplasma genitalium have increased in last decade. This epidemiological scenario presents new challenges in order to improve and strengthen our control and prevention strategies. The routine clinical diagnosis of urethritis and cervicitis must be combined with the active search for the causal agent in men with symptoms of dysuria or proctitis, and in women with pelvic inflammatory disease. Read More

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http://dx.doi.org/10.1016/j.eimc.2019.01.014DOI Listing
March 2019
2 Reads

Rectal syphilis in a HIV patient from Peru.

Rev Gastroenterol Peru 2018 Oct-Dec;38(4):381-383

Servicio de Patología, Hospital Nacional Arzobispo Loayza. Lima, Perú.

We present the case of a 53-year-old male patient, a man who had sex with men. He described the presence of inguinal adenopathy and non-painful ulcer with indurated edges on his penis that heal spontaneously after 3 months. In the same period of time the patient presented: tenesmus, bleeding and rectal pain. Read More

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A comprehensive review and update on ulcerative colitis.

Dis Mon 2019 Mar 2. Epub 2019 Mar 2.

Division of Gastroenterology, American University of Beirut, Beirut, Lebanon; Division of Gastroenterology, Hepatology and Nutrition, University of Pittsburgh, M2, C Wing, 200 Lothrop Street, Pittsburgh, PA 15213, USA.

Ulcerative colitis (UC) is a chronic idiopathic inflammatory bowel disorder of the colon that causes continuous mucosal inflammation extending from the rectum to the more proximal colon, with variable extents. UC is characterized by a relapsing and remitting course. UC was first described by Samuel Wilks in 1859 and it is more common than Crohn's disease worldwide. Read More

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http://dx.doi.org/10.1016/j.disamonth.2019.02.004DOI Listing
March 2019
5 Reads

Stereotactic Re-irradiation for Local Recurrence in the Prostatic Bed After Prostatectomy: Preliminary Results.

Front Oncol 2019 15;9:71. Epub 2019 Feb 15.

Academic Department of Radiation Oncology, Centre Oscar Lambret, Lille, France.

To report the preliminary results of salvage re-irradiation in the prostatic bed after radical prostatectomy and salvage external beam radiation therapy (EBRT) using robotic stereotactic body radiation therapy (SBRT) with Cyberknife® for local recurrence of prostate cancer. Retrospective monocentric analysis was performed on patients treated with SBRT for isolated macroscopic recurrence in the prostatic bed. All patients had radical prostatectomy and salvage or adjuvant EBRT. Read More

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http://dx.doi.org/10.3389/fonc.2019.00071DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384250PMC
February 2019
3 Reads

Ulcerative Colitis: Shifting Sands.

Drugs R D 2019 Mar 2. Epub 2019 Mar 2.

Klinik für Innere Medizin I, Universitätsklinikum Schleswig-Holstein, Campus Kiel, 24105, Kiel, Germany.

Ulcerative colitis (UC) is a chronic inflammatory bowel disease associated with considerable disease burden. We review some current misconceptions about UC in adults with the aim of optimizing care for patients. Although UC and Crohn's disease (CD) are considered discrete diseases, distinctions between them are not always clear-cut and phenotypes may change over time. Read More

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http://dx.doi.org/10.1007/s40268-019-0263-2DOI Listing

Risk factors and timing for colectomy in chronically active refractory ulcerative colitis: A systematic review.

Dig Liver Dis 2019 Feb 6. Epub 2019 Feb 6.

IBD Unit, "Villa Sofia-Cervello" Hospital, Palermo, Italy.

Background: In patients with chronic refractory ulcerative colitis (UC) the precise timing for indication to colectomy is unclear.

Aims: We performed a systematic review of the literature on the risk factors for colectomy in patients with chronic refractory UC in the biologic era.

Methods: PubMed Central/Medline and Embase were systemically searched for records published between January 2000 and December 2017. Read More

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http://dx.doi.org/10.1016/j.dld.2019.01.018DOI Listing
February 2019
2 Reads

Rectal retractor application during image-guided dose-escalated prostate radiotherapy.

Strahlenther Onkol 2019 Mar 1. Epub 2019 Mar 1.

Department of Biostatistics, School of Public Health, Iran University of Medical Sciences, Tehran, Iran.

Purpose: To investigate efficacy of a rectal retractor (RR) on rectal dose during image-guided dose-escalated prostate three-dimensional conformal radiotherapy (3DCRT).

Patients And Methods: In all, 21 patients with localized prostate cancer were treated with a RR for 3DCRT in 40 × 2 Gy. Patient underwent two scans for radiotherapy planning, without and with RR. Read More

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http://dx.doi.org/10.1007/s00066-019-01445-6DOI Listing
March 2019
5 Reads

Tacrolimus Suppositories in Therapy-Resistant Ulcerative Proctitis.

Inflamm Intest Dis 2019 Feb 9;3(3):116-124. Epub 2018 Nov 9.

Department of Internal Medicine I, University Hospital, University of Tübingen, Tübingen, Germany.

Background: Ulcerative proctitis may often be managed with topical salicylates or steroids alone, but in some patients, symptoms are persistent and severe. We analyzed the efficacy of tacrolimus suppositories in patients who had proven refractory to combined topical and systemic treatment.

Methods: In this retrospective analysis, ulcerative colitis activity index (CAI), side effects, co-medication and drug levels were assessed in 43 patients with distal ulcerative colitis who received suppositories containing 2 mg of tacrolimus b. Read More

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http://dx.doi.org/10.1159/000493979DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390495PMC
February 2019

Lymphogranuloma venereum (LGV) proctocolitis mimicking rectal lymphoma.

Radiol Case Rep 2018 Dec 13;13(6):1119-1122. Epub 2018 Sep 13.

Division of Gastroenterology, Department of Medicine, Duke University Medical Center, 2400 Pratt Street, Suite 8007, Durham, NC 27710, USA.

Lymphogranuloma venereum is a sexually transmitted infection caused by serotypes L1-3 of and may present as hemorrhagic proctocolitis. The diagnosis of an active infection is difficult to establish, as confirmatory testing can be unreliable or unavailable. Imaging findings can be nonspecific and mimic malignancy or other chronic infectious and inflammatory disorders. Read More

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http://dx.doi.org/10.1016/j.radcr.2018.08.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372233PMC
December 2018
1 Read

Rectal Lymphogranuloma Venereum, Buenos Aires, Argentina.

Emerg Infect Dis 2019 Mar;25(3):598-599

Among 34 men with proctitis in Buenos Aires, Argentina, 16 (47%) had Chlamydia trachomatis infection, 11 (68.8%) of which were biovar lymphogranuloma venereum. The outbreak was probably local, as in Europe. Read More

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http://dx.doi.org/10.3201/eid2503.180600DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390746PMC
March 2019
1 Read

Total neoadjuvant approach with FOLFOXIRI plus bevacizumab followed by chemoradiotherapy plus bevacizumab in locally advanced rectal cancer: the TRUST trial.

Eur J Cancer 2019 Mar 7;110:32-41. Epub 2019 Feb 7.

Unit of Medical Oncology 2, Azienda Ospedaliero-Universitaria Pisana, Via Roma, 56126 Pisa, Italy; Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Via Roma, 56126 Pisa, Italy. Electronic address:

Background: Neoadjuvant chemoradiotherapy (CRT) in locally advanced rectal cancer (LARC) does not achieve effective control of distant metastases. Induction chemotherapy is a promising strategy, and bevacizumab (BV) could improve the results of CRT. 5-Fluorouracil, oxaliplatin and irinotecan (FOLFOXIRI) plus BV is a treatment option in metastatic colorectal cancer. Read More

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http://dx.doi.org/10.1016/j.ejca.2019.01.006DOI Listing
March 2019
2 Reads

A rare case of Fitz-Hugh-Curtis syndrome caused by in an HIV-positive male patient.

SAGE Open Med Case Rep 2019 16;7:2050313X18823592. Epub 2019 Jan 16.

University Hospital for Infectious Diseases 'Dr. Fran Mihaljević', Zagreb, Croatia.

Fitz-Hugh-Curtis syndrome, a rare complication of pelvic inflammatory disease, is an inflammation of the liver capsule (thus called perihepatitis) and the surrounding peritoneum. It occurs extremely rarely in men and is typically characterized by a sudden onset of severe pain in the right upper abdominal quadrant. Ultrasound examination of the liver does not reveal any morphologic changes, and liver function tests are usually normal. Read More

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http://dx.doi.org/10.1177/2050313X18823592DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350016PMC
January 2019
5 Reads

A case report of proctitis associated with Mycoplasma genitalium in a man who has sex with men.

Int J STD AIDS 2019 Feb 5:956462419825896. Epub 2019 Feb 5.

3 STI Unit Vall d'Hebron - Drassanes, Infectious Diseases Department, Hospital Vall d'Hebron, Barcelona, Spain.

Mycoplasma genitalium is an infection of increasing concern due to its potential to cause sequelae in the reproductive tract and the development of antimicrobial resistance. Its role as a cause of proctitis in people with high-risk sexual behaviour has not been properly defined yet but it seems to be less symptomatic than proctitis caused by Chlamydia trachomatis or Neisseria gonorrhoeae. We present a case of a man who has sex with men with proctitis associated with M. Read More

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http://dx.doi.org/10.1177/0956462419825896DOI Listing
February 2019
2 Reads

Gastrointestinal: Radiation proctitis: Or is it something else?

J Gastroenterol Hepatol 2019 Jan 28. Epub 2019 Jan 28.

Department of Gastroenterology, GB Pant Institute of Post Graduate Medical Education and Research, New Delhi, India.

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http://dx.doi.org/10.1111/jgh.14592DOI Listing
January 2019
1 Read

Rubber Band Ligation of Hemorrhoids is often a Necessary Complement in the Management of Hemorrhagic Radiation Proctitis.

Scand J Surg 2019 Jan 11:1457496918822619. Epub 2019 Jan 11.

1 Department of Colorectal Surgery, Royal Prince Alfred Hospital, Sydney, NSW, Australia.

Background:: Management of radiation proctitis presents a treatment challenge. Limited data exist on the management of symptomatic hemorrhoids in radiated patients. This study aims to present a practical approach to the management of radiation proctitis, particularly in patients with synchronous hemorrhoids. Read More

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http://dx.doi.org/10.1177/1457496918822619DOI Listing
January 2019
2 Reads

Rectal Submucosal Tumor Mimicking a Neuroendocrine Tumor.

Intern Med 2019 Jan 10. Epub 2019 Jan 10.

Department of Gastroenterology and Hepatology, Kyoto University Graduate School of Medicine, Japan.

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http://dx.doi.org/10.2169/internalmedicine.2171-18DOI Listing
January 2019

A Phase 1 Pilot Study of Preoperative Radiation Therapy for Prostate Cancer: Long-Term Toxicity and Oncologic Outcomes.

Int J Radiat Oncol Biol Phys 2019 May 6;104(1):61-66. Epub 2019 Jan 6.

Department of Radiation Oncology, University of Toronto, Toronto, Canada; Radiation Medicine Program, Princess Margaret Cancer Centre, University Health Network, Toronto, Canada; Techna Institute, University Health Network, Toronto, Canada. Electronic address:

Purpose: Neoadjuvant radiation therapy (RT) improves disease control in various cancers and has become an established oncologic treatment strategy. During 2001 to 2004, we conducted a phase 1 pilot study assessing the role of short-course preoperative RT (PreORT) for men with unfavorable intermediate- and high-risk localized prostate cancer. Herein, we present long-term follow-up toxicity and oncologic outcomes. Read More

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http://dx.doi.org/10.1016/j.ijrobp.2018.12.054DOI Listing
May 2019
8 Reads

[Chinese consensus on diagnosis and treatment of radiation proctitis (2018)].

Zhonghua Wei Chang Wai Ke Za Zhi 2018 Dec;21(12):1321-1336

Surgeon Branch of Chinese Medical Doctor Association, Colorectal Surgery Group of Surgery Branch in the Chinese Medical Association.

Radiation proctitis denotes the radiation damage of rectum caused by radiotherapy to pelvic malignancy. The clinical practices of radiation proctitis should be fully considered from diagnosis, treatment and prevention. In order to determine appropriate treatment strategies, the diagnosis of radiation proctitis should be based on clinical symptoms, endoscopic findings, imaging and histopathology to assess severity of symptoms and stage of disease. Read More

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December 2018
42 Reads

Argon plasma coagulation is an effective treatment for chronic radiation proctitis in gynaecological malignancy: an observational study.

Colorectal Dis 2019 Apr 22;21(4):465-471. Epub 2019 Jan 22.

Department of Gastroenterology, School of Digestive and Liver disease, Kolkata, West Bengal, India.

Aim: Chronic radiation proctitis (CRP) develops in 5-15% of patients after pelvic radiation therapy, with rectal bleeding being the main symptom. Reports suggest that argon plasma coagulation (APC) can be an effective therapy for CRP following radiotherapy for prostate cancer, but there is less information about how useful it is after radiotherapy for gynaecological malignancy. The aim of this work therefore was to study the efficacy of APC for CRP after radiotherapy for gynaecological malignancy. Read More

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http://dx.doi.org/10.1111/codi.14541DOI Listing
April 2019
1 Read

Looking at the positives: proactive management of STIs in people with HIV.

AIDS Res Ther 2018 Dec 21;15(1):28. Epub 2018 Dec 21.

Melbourne Sexual Health Centre, Alfred Health, Melbourne, VIC, Australia.

Patients who are HIV-positive and co-infected with other sexually transmitted infections (STIs) are at risk of increased morbidity and mortality. This is of clinical significance. There has been a dramatic increase in the incidence of STIs, particularly syphilis, gonorrhoea, Mycoplasma genitalium and hepatitis C virus (HCV) in HIV-positive patients. Read More

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https://aidsrestherapy.biomedcentral.com/articles/10.1186/s1
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http://dx.doi.org/10.1186/s12981-018-0216-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302453PMC
December 2018
15 Reads

[Diagnostic validity of fecal occult blood test in infants with food protein-induced allergic proctocolitis].

Rev Chil Pediatr 2018 Oct;89(5):630-637

Laboratorio de Inmunología y Alergia Traslacional, Departamento de Enfermedades Infecciosas e Inmunología Pediátrica, Pontificia Universidad Católica de Chile, Chile.

Introduction: Food protein-induced allergic proctocolitis (FPIAP) is the most frequent presenta tion of non-IgE mediated food allergy (FA). The diagnosis is made by oral food challenge, however, non-invasive diagnostic tests are not available. In Chile, the fecal occult blood test (FOBT) is fre quently used to confirm FPIAP, however, there are no studies that support this practice. Read More

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http://dx.doi.org/10.4067/S0370-41062018005000901DOI Listing
October 2018
5 Reads

Interference with the lower gut-liver axis induces remission of primary sclerosing cholangitis in a patient with ulcerative colitis.

BMJ Open Gastroenterol 2018 14;5(1):e000239. Epub 2018 Nov 14.

Department of Gastroenterology, Bedford Hospital South Wing, Bedford, UK.

The gut-liver axis describes the complex interactions between gut microbiota, the small and large bowel, the immune system and the liver. Current evidence associates abnormalities within the gut-liver axis with liver disease such as primary sclerosing cholangitis (PSC). PSC is believed to be an immune-mediated disease though the exact mechanism of its pathogenesis remains unknown. Read More

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http://dx.doi.org/10.1136/bmjgast-2018-000239DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6267462PMC
November 2018
2 Reads

THE ONSET OF CLINICAL MANIFESTATIONS IN INFLAMMATORY BOWEL DISEASE PATIENTS.

Arq Gastroenterol 2018 Jul-Sep;55(3):290-295

Universidade do Estado da Bahia, Departamento de Ciências da Vida, Salvador, BA, Brasil.

Background: The diagnosis of inflammatory bowel disease is often delayed because of the lack of an ability to recognize its major clinical manifestations.

Objective: Our study aimed to describe the onset of clinical manifestations in inflammatory bowel disease patients.

Methods: A cross-sectional study. Read More

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S
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http://dx.doi.org/10.1590/S0004-2803.201800000-73DOI Listing
January 2019
7 Reads

A Case of Asymptomatic Syphilitic Proctitis.

Sex Transm Dis 2018 Dec 3. Epub 2018 Dec 3.

Division of Infectious Diseases, Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles.

The incidence of syphilis is increasing. Syphilitic proctitis involving the rectal mucosa often presents with pain on defecation, rectal bleeding, or ulceration. We present a case of asymptomatic syphilitic proctitis diagnosed upon a routine screening colonoscopy. Read More

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http://dx.doi.org/10.1097/OLQ.0000000000000955DOI Listing
December 2018
4 Reads

Acetarsol in the management of mesalazine-refractory ulcerative proctitis: a tertiary-level care experience.

Eur J Gastroenterol Hepatol 2019 02;31(2):183-186

Nottingham Digestive Diseases Centre.

Background: Mesalazine-refractory ulcerative proctitis is common, with a significant proportion of the patients requiring escalation to immunomodulators or biological therapy. Three small preliminary cohort studies suggested good clinical efficacy for the organic arsenic derivative acetarsol in the management of proctitis. Our aim was to describe our experience on the use of acetarsol in proctitis and to review all existing evidence on its safety and efficacy. Read More

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http://dx.doi.org/10.1097/MEG.0000000000001326DOI Listing
February 2019
26 Reads

Epidemiology and clinical course of inflammatory bowel disease in the Central Province of Sri Lanka: A hospital-based study.

JGH Open 2018 Aug 6;2(4):129-133. Epub 2018 Jun 6.

Gastroenterology and Hepatology Unit Teaching Hospital Kandy Kandy Sri Lanka.

Background And Aim: There is increasing prevalence of inflammatory bowel disease (IBD) in Asia, but Sri Lankan data on the state of epidemiology and clinical course of IBD are scarce.

Methods: A hospital-based study was done by recruiting IBD patients who permanently reside in the Central Province (population 2.57 million, 12. Read More

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http://doi.wiley.com/10.1002/jgh3.12058
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http://dx.doi.org/10.1002/jgh3.12058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6207030PMC
August 2018
7 Reads

Hyaluronic acid for treatment of the radiation therapy side effects: a systematic review.

Authors:
D Cosentino F Piro

Eur Rev Med Pharmacol Sci 2018 Nov;22(21):7562-7572

Radiotherapy Oncology Center, Azienda Ospedaliera of Cosenza, Cosenza, Italy.

Objective: The main limit of radiation therapy is the dose-dependent toxicity to healthy tissues. The 36% of patients exposed to radiotherapy for pelvic malignancies reporting gastrointestinal symptoms as incontinence, pain, mucus discharge, and bleeding (radiation proctopathy). In the cervix cancer, healthy tissues exposed to radiations easily develop inflammation of vaginal mucosa, bleeding and pain and to improve these symptoms, some medical devices were developed. Read More

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http://dx.doi.org/10.26355/eurrev_201811_16298DOI Listing
November 2018
11 Reads

Randomized, double-blind, placebo-controlled phase II trial of nanocurcumin in prostate cancer patients undergoing radiotherapy.

Phytother Res 2019 Feb 14;33(2):370-378. Epub 2018 Nov 14.

Urology and Nephrology Research Center, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Clinical potential of curcumin in radiotherapy (RT) setting is outstanding and of high interest. The main purpose of this randomized controlled trial (RCT) was to assess the beneficial role of nanocurcumin to prevent and/or mitigate radiation-induced proctitis in prostate cancer patients undergoing RT. In this parallel-group study, 64 eligible patients with prostate cancer were randomized to receive either oral nanocurcumin (120 mg/day) or placebo 3 days before and during the RT course. Read More

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http://doi.wiley.com/10.1002/ptr.6230
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http://dx.doi.org/10.1002/ptr.6230DOI Listing
February 2019
9 Reads

Oral Adjuvant Curcumin Therapy for Attaining Clinical Remission in Ulcerative Colitis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Nutrients 2018 Nov 12;10(11). Epub 2018 Nov 12.

Department of Rheumatology and Clinical Immunology, Faculty of Medicine, School of Health Sciences, University of Thessaly, Biopolis, GR41110 Larissa, Greece.

Curcumin has demonstrated anti-inflammatory properties and has been investigated as an adjuvant therapy of ulcerative colitis (UC). The scope of this study was to systematically review and meta-analyze the efficacy of oral curcumin administration as an adjuvant therapy of UC. MEDLINE, Cochrane/CENTRAL, ClinicalTrials. Read More

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http://www.mdpi.com/2072-6643/10/11/1737
Publisher Site
http://dx.doi.org/10.3390/nu10111737DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6266508PMC
November 2018
16 Reads

Concurrent Chemo- Radiobrachytherapy with Cisplatin and Medium Dose Rate Intra- Cavitary Brachytherapy for Locally Advanced Uterine Cervical Cancer

Asian Pac J Cancer Prev 2018 Oct 26;19(10):2745-2750. Epub 2018 Oct 26.

Radiation Oncology Research Center, Department of Radiation Oncology, Cancer Institute, Tehran University of Medical Sciences, Tehran, Iran. Email:

Objective: Cervical carcinoma is the third most common gynecologic cancer, after ovarian and uterine cancers in Iran. The aim of this study was to evaluate the efficacy (response rate) and toxicity of adding Medium Dose Rate (MDR) brachytherapy with concurrent chemotherapy to External Beam Radiotherapy (EBRT) for the treatment of locally advanced uterine cervical carcinoma. Methods: This phase I-II study was conducted in 2007-2008 at the cancer institute, Tehran University of Medical Sciences. Read More

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http://journal.waocp.org/article_70390.html
Publisher Site
http://dx.doi.org/10.22034/APJCP.2018.19.10.2745DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291044PMC
October 2018
13 Reads

Endoscopic progression of ulcerative proctitis to proximal disease. Can we identify predictors of progression?

Scand J Gastroenterol 2018 Oct - Nov;53(10-11):1286-1290. Epub 2018 Oct 23.

a Digestive Disease Department , General University Hospital of Valencia , Valencia , Spain.

Introduction: Ulcerative proctitis is a type of ulcerative colitis circumscribed to the rectum. Proximal progression rates of the disease have been reported as between 27% and 54%. Several predictive factors have been identified for its progression; however, none has been established as definitive. Read More

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https://www.tandfonline.com/doi/full/10.1080/00365521.2018.1
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http://dx.doi.org/10.1080/00365521.2018.1524026DOI Listing
April 2019
13 Reads

Primary syphilitic proctitis : case report and literature review.

Acta Gastroenterol Belg 2018 Jul-Sep;81(3):430-432

Department of Gastroenterology, University Hospital Gasthuisberg, Leuven, Belgium.

Rectal ulcerations are an uncommon presentation of a primary syphilis infection. Anorectal syphilis is difficult to diagnose because of its often asymptomatic or atypical clinical presentation. It is important to consider sexually transmitted diseases (STD) in all patients presenting with rectal symptoms. Read More

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February 2019
6 Reads

Rectal Lymphoid Follicle Aphthous Lesions Frequently Progress to Ulcerative Colitis with Proximal Extension.

Intern Med 2019 Mar 17;58(5):625-631. Epub 2018 Oct 17.

Department of Gastroenterology and Metabolism, Hiroshima University Hospital, Japan.

Objective Rectal lymphoid follicular aphthous (LFA) lesions are related to ulcerative colitis (UC) and can be initial lesions of UC. We investigated the clinical course and prognosis of rectal LFA lesions. Methods This is a retrospective analysis of the clinical records at a single center. Read More

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http://dx.doi.org/10.2169/internalmedicine.1635-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443555PMC
March 2019
10 Reads

Usefulness of fecal calprotectin by monoclonal antibody testing in adult Japanese with inflammatory bowel diseases: a prospective multicenter study.

Intest Res 2018 Oct 10;16(4):554-562. Epub 2018 Oct 10.

Department of Medicine, Shiga University of Medical Science, Otsu, Japan.

Background/aims: Noninvasive objective monitoring is advantageous for optimizing treatment strategies in patients inflammatory bowel disease (IBD). Fecal calprotectin (FCP) is superior to traditional biomarkers in terms of assessing the activity in patients with IBD. However, there are the differences among several FCP assays in the dynamics of FCP. Read More

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http://irjournal.org/journal/view.php?doi=10.5217/ir.2018.00
Publisher Site
http://dx.doi.org/10.5217/ir.2018.00027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6223455PMC
October 2018
18 Reads