52,789 results match your criteria Proceedings of the Royal Society B - Biological Sciences [Journal]


Maternal probiotic supplementation for prevention of morbidity and mortality in preterm infants.

Cochrane Database Syst Rev 2018 Dec 12;12:CD012519. Epub 2018 Dec 12.

University of Vermont Medical Center, Burlington VT, USA.

Background: Inflammation may contribute to preterm birth and to morbidity of preterm infants. Preterm infants are at risk for alterations in the normal protective microbiome. Oral probiotics administered directly to preterm infants have been shown to decrease the risk for severe necrotizing enterocolitis (NEC) as well as the risk of death, but there are safety concerns about administration of probiotics directly to preterm infants. Read More

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December 2018

Conference proceedings of the 4th Masterclass Psychiatry: Transcultural Psychiatry - Diagnostics and Treatment, Luleå, Sweden, 22-23 February 2018 (Region Norrbotten in collaboration with the Maudsley Hospital and Tavistock Clinic London).

Authors:
Ursula Werneke

Nord J Psychiatry 2018 Dec 14. Epub 2018 Dec 14.

a Department of Clinical Sciences, Division of Psychiatry, Sunderby Research Unit , Umeå University , Umeå , Sweden.

Background: According to estimates from the European Commission, Europe has experienced the greatest mass movement of people since the Second World War. More than one million refugees and migrants have arrived in the European Union in the past few years. Mental health and primary care professionals are more likely than ever to meet patients from different cultures and backgrounds. Read More

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December 2018

Proceedings of the 8th International Conference on Children's Health and the Environment.

Authors:

J Health Pollut 2016 Dec 19;6(12):S1-S154. Epub 2016 Dec 19.

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December 2016

Proceedings of the 2018 next-generation Gamma Knife research meeting.

Authors:

J Neurosurg 2018 Dec;129(Suppl1):5-9

In order to determine what areas of research are a clinical priority, a small group of young Gamma Knife investigators was invited to attend a workshop discussion at the 19th International Leksell Gamma Knife Society Meeting. Two areas of interest and the need for future radiosurgical research involving multiple institutions were identified by the young investigators working group: 1) the development of additional imaging sequences to guide the understanding, treatment, and outcome tracking of diseases such as tremor, radiation necrosis, and AVM; and 2) trials to clarify the role of hypofractionation versus single-fraction radiosurgery in the treatment of large lesions such as brain metastases, postoperative cavities, and meningiomas. Read More

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December 2018

Clinical Opinion Letters Regarding Breastfeeding and Neonatal Abstinence Syndrome for Child Apprehension Family Court Proceedings.

J Hum Lact 2018 Dec 13:890334418818421. Epub 2018 Dec 13.

1 Dalhousie University School of Nursing, Halifax, NS, Canada.

The accelerating reach of opioid use disorder in North America includes increasing prevalence among pregnant people. In Canada, the rate of Neonatal Abstinence Syndrome (NAS) rose 27% between 2012-2013 and 2016-2017, and it is estimated that 0.51% of all infants now experience NAS after delivery. Read More

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December 2018

Contrast-enhanced ultrasound and/or colour duplex ultrasound for surveillance after endovascular abdominal aortic aneurysm repair: a systematic review and economic evaluation.

Health Technol Assess 2018 Dec;22(72):1-220

Regional Vascular Unit, Royal Liverpool University Hospital, Liverpool, UK.

Background: Endovascular abdominal aortic aneurysm repair (EVAR) of abdominal aortic aneurysm (AAA) is less invasive than open surgery, but may be associated with important complications. Patients receiving EVAR require long-term surveillance to detect abnormalities and direct treatments. Computed tomography angiography (CTA) has been the most common imaging modality adopted for EVAR surveillance, but it is associated with repeated radiation exposure and the risk of contrast-related nephropathy. Read More

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December 2018

[Proceedings of Regional Meeting of the Japan Geriatrics Society].

Authors:

Nihon Ronen Igakkai Zasshi 2018 ;55(4):698-733

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January 2018

Proceedings of the 9th International Conference on Children's Health and the Environment.

Authors:

J Health Pollut 2018 Sep 10;8(19):180908. Epub 2018 Sep 10.

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September 2018

Cockroaches, locusts, and envenomating arthropods: a promising source of antimicrobials.

Iran J Basic Med Sci 2018 Sep;21(9):873-877

Department of Biological Sciences, School of Science and Technology, Sunway University, Selangor, Malaysia.

Objectives: To present a brief overview of various natural sources of antimicrobials with the aim of highlighting invertebrates living in polluted environments as additional sources of antimicrobials.

Materials And Methods: A PubMed search using antibacterials, antimicrobials, invertebrates, and natural products as keywords was carried out. In addition, we consulted conference proceedings, original unpublished research undertaken in our laboratories, and discussions in specific forums. Read More

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September 2018

Understanding Subdural Collections in Pediatric Abusive Head Trauma.

AJNR Am J Neuroradiol 2018 Dec 6. Epub 2018 Dec 6.

Institute of Diagnostic and Interventional Radiology and Neuroradiology (M.L.H.), University Hospital Essen, Essen, Germany.

Life-threatening physical abuse of infants and toddlers is frequently correlated with head injuries. A common variant of the abusive head trauma is the shaken baby syndrome. The present review article sheds light on subdural collections in children with abusive head trauma and aims at providing a recent knowledge base for various medical disciplines involved in diagnostic procedures and legal proceedings. Read More

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December 2018

Immaculate Conception of Los Venerables by Bartolomé Estaban Murillo.

Authors:
Margaret R Wentz

Mayo Clin Proc 2018 Dec;93(12):e131-e132

Recognizing the contribution art has had in the Mayo Clinic environment since the original Mayo Clinic Building was finished in 1914, Mayo Clinic Proceedings features some of the numerous works of art displayed throughout the buildings and grounds on Mayo Clinic campuses as interpreted by the author. Read More

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December 2018

ASET 59th Annual Conference Proceedings.

Authors:

Neurodiagn J 2018 ;58(4):235-256

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January 2018

Conclusions of the digital health hub of the Transform Africa Summit (2018): strong government leadership and public-private-partnerships are key prerequisites for sustainable scale up of digital health in Africa.

BMC Proc 2018 15;12(Suppl 11):17. Epub 2018 Aug 15.

WHO Country Office, Kigali, Rwanda.

Background: The use of digital technologies to improve access to health is gaining momentum in Africa. This is more pertinent with the increasing penetration of mobile phone technology and internet use, and calls for innovative strategies to support implementation of the health-related Sustainable Development Goals and Universal Health Coverage on the continent. However, the huge potential benefits of digital health to advance health services delivery in Africa is yet to be fully harnessed due to critical challenges such as proliferation of pilot projects, poor coordination, inadequate preparedness of the African health workforce for digital health, lack of interoperability and inadequate sustainable financing, among others. Read More

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Capecitabine monotherapy in advanced breast cancer resistant to anthracycline and taxane: A meta-analysis.

J Cancer Res Ther 2018 Dec;14(Supplement):S957-S963

Department of Integrative Oncology, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center of Cancer, Key Laboratory of Breast Cancer Prevention and Therapy, Ministry of Education, Tianjin Key Laboratory of Cancer Prevention and Therapy, Tianjin, China.

Background: Capecitabine monotherapy is usually used for advanced breast cancer (ABC) resistant to anthracycline and taxane, but there are still many other options too. Our meta-analysis assessed whether capecitabine monotherapy was superior or noninferior to the other regimens in ABC pretreated with anthracycline and taxane.

Materials And Methods: PubMed databases and abstracts from the proceedings of American Society of Clinical Oncology and San Antonio Breast Cancer Symposium were searched for randomized controlled trials that compared capecitabine monotherapy with other regimens for ABC progression after anthracycline- and taxane-treatment. Read More

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December 2018

Comparison of body weight estimation equations for camels (Camelus dromedarius).

Trop Anim Health Prod 2018 Dec 11. Epub 2018 Dec 11.

Department of Animal Production and Biotechnology, Institut Agronomique et Vétérinaire Hassan II, PO Box 6202, Rabat-Instituts, 10101, Rabat, Morocco.

The objective of the present study was to evaluate the accuracy of six different equations for weight estimation of camels using body measurements as chest girth, height at withers, and hump girth in order to identify the most reliable equation for use in the field. The prediction equations that were compared were those of Boué Revue d'Élevage et de Médecine vétérinaire des Pays tropicaux 3 (1), 13-16, 1949; Graber Revue d'Élevage et de Médecine vétérinaire des Pays tropicaux, 19, 527-543, 1966; Wilson Tropical Animal Health and Production, 10, 19-25, 1978; Field Proceedings of the Khartoum workshop on camels V1, 209-230, 1979; Bucci et al. Indian Veterinary Journal, 61, 26-30, 1984; and Yagil A Handbook for Camel Breeding, 1994 noticed as BW1, BW2, BW3, BW4, BW5, and BW6, respectively. Read More

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December 2018

Laryngeal mask airway versus endotracheal tube for percutaneous dilatational tracheostomy in critically ill adults.

Cochrane Database Syst Rev 2018 Nov 15;11:CD009901. Epub 2018 Nov 15.

Wiesbaden Business School, RheinMain University of Applied Science, Bleichstr. 44, Wiesbaden, Germany, 65183.

Background: Percutaneous dilatational tracheostomy (PDT) is one of the most common bedside surgical procedures performed in critically ill adults, on intensive care units (ICUs), who require long-term ventilation. PDT is associated with relevant life-threatening complications: Cuff rupture or accidental extubation may lead to hypoxia, aspiration or loss of airway. Puncture of the oesophagus, or creating a false passage during dilatation or replacement of the tracheostomy tube, can lead to pneumothorax or emphysema. Read More

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November 2018
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Pharmacotherapy in Older Adults with Cardiovascular Disease: Report from an American College of Cardiology, American Geriatrics Society, and National Institute on Aging Workshop.

J Am Geriatr Soc 2018 Dec 7. Epub 2018 Dec 7.

Cardiovascular Division, Department of Internal Medicine, Washington University, St. Louis, Missouri.

Objectives: To identify the top priority areas for research to optimize pharmacotherapy in older adults with cardiovascular disease (CVD).

Design: Consensus meeting.

Setting: Multidisciplinary workshop supported by the National Institute on Aging, the American College of Cardiology, and the American Geriatrics Society, February 6-7, 2017. Read More

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December 2018
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Systematic Review: Efficacy and Safety of Accelerated Induction Regimes in Infliximab Rescue Therapy for Hospitalized Patients with Acute Severe Colitis.

Dig Dis Sci 2018 Dec 7. Epub 2018 Dec 7.

The Royal Liverpool and Broad Green University Hospitals NHS Foundation Trust, Liverpool, UK.

Background: Pharmacokinetic data suggest that standard induction dosing schedules may not be sufficient in patients with acute severe colitis (ASUC). Hence, intensified induction regimes are increasingly used in the rescue treatment of hospitalized patients with ASUC to avoid the need for colectomy although the evidence for this is uncertain.

Aim: To conduct a systematic review of short- and long-term efficacy outcomes from accelerated infliximab induction studies. Read More

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December 2018
1 Read

Conference proceedings.

Authors:
N Gopi Chander

J Indian Prosthodont Soc 2018 Oct;18(Suppl 1):S1

Editor The Journal of Indian Prosthodontic Society, Department of Prosthodontics, SRM Dental College, SRM University, Chennai, Tamil Nadu, India.

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October 2018

Psychosocial interventions to reduce alcohol consumption in concurrent problem alcohol and illicit drug users.

Cochrane Database Syst Rev 2018 Dec 5;12:CD009269. Epub 2018 Dec 5.

BC Centre on Substance Use, BC Centre for Excellence in HIV/AIDS, 611 Powell Street, Vancouver, BC, Canada, V6A 1H2.

Background: Problem alcohol use is common among people who use illicit drugs (PWID) and is associated with adverse health outcomes. It is also an important factor contributing to a poor prognosis among drug users with hepatitis C virus (HCV) as it impacts on progression to hepatic cirrhosis or opioid overdose in PWID.

Objectives: To assess the effectiveness of psychosocial interventions to reduce alcohol consumption in PWID (users of opioids and stimulants). Read More

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December 2018
6 Reads

Vaccines for preventing invasive salmonella infections in people with sickle cell disease.

Cochrane Database Syst Rev 2018 Dec 5;12:CD006975. Epub 2018 Dec 5.

Department of Paediatrics, University of Calabar Teaching Hospital, PMB 1115, Calabar, Cross River State, Nigeria, 540261.

Background: Salmonella infections are a common bacterial cause of invasive disease in people with sickle cell disease especially children, and are associated with high morbidity and mortality rates. Although available in some centres, people with sickle cell anaemia are not routinely immunized with salmonella vaccines. This is an update of a previously published Cochrane Review. Read More

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December 2018
7 Reads

Pre-emptive and preventive opioids for postoperative pain in adults undergoing all types of surgery.

Cochrane Database Syst Rev 2018 Dec 3;12:CD012624. Epub 2018 Dec 3.

Department of Surgery and Anaesthesia, Division of Medical Sciences and Graduate Entry Medicine, School of Medicine, University of Nottingham, Uttoxeter New Road, Derby, UK, DE22 3DT.

Background: Postoperative pain is a common consequence of surgery and can have deleterious effects. It has been suggested that the administration of opioid analgesia before a painful stimulus may improve pain control. This can be done in two ways. Read More

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December 2018
8 Reads

Hysteroscopy for treating subfertility associated with suspected major uterine cavity abnormalities.

Cochrane Database Syst Rev 2018 Dec 5;12:CD009461. Epub 2018 Dec 5.

Academic Centre for General Practice, Cochrane Belgium, Kapucijnenvoer 33, blok J bus 7001, Leuven, Belgium, 3000.

Background: Observational studies suggest higher pregnancy rates after the hysteroscopic removal of endometrial polyps, submucous fibroids, uterine septum or intrauterine adhesions, which are present in 10% to 15% of women seeking treatment for subfertility.

Objectives: To assess the effects of the hysteroscopic removal of endometrial polyps, submucous fibroids, uterine septum or intrauterine adhesions suspected on ultrasound, hysterosalpingography, diagnostic hysteroscopy or any combination of these methods in women with otherwise unexplained subfertility or prior to intrauterine insemination (IUI), in vitro fertilisation (IVF) or intracytoplasmic sperm injection (ICSI).

Search Methods: We searched the following databases from their inception to 16 April 2018; The Cochrane Gynaecology and Fertility Group Specialised Register, the Cochrane Central Register of Studies Online, ; MEDLINE, Embase , CINAHL , and other electronic sources of trials including trial registers, sources of unpublished literature, and reference lists. Read More

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December 2018
1 Read

Effect of regional versus general anaesthesia on postoperative delirium in elderly patients undergoing surgery for hip fracture: a systematic review.

BMJ Open 2018 Dec 4;8(12):e020757. Epub 2018 Dec 4.

Warwick Medical School, University of Warwick, Coventry, UK.

Objective: Older patients with hip fractures who are undergoing surgery are at high risk of significant mortality and morbidity including postoperative delirium. It is unclear whether different types of anaesthesia may reduce the incidence of postoperative delirium. This systematic review will investigate the impact of anaesthetic technique on postoperative delirium. Read More

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December 2018
1 Read

Alcohol markers in hair: an issue of interpretation.

Authors:
Richard Paul

Forensic Sci Med Pathol 2018 Nov 30. Epub 2018 Nov 30.

Faculty of Science and Technology, Bournemouth University, Poole, BH12 5BB, UK.

Ethyl glucuronide (EtG) and fatty acid ethyl esters (FAEEs) are metabolites of alcohol that when detected in hair can provide evidence of a person's drinking behavior. The analysis of these compounds in hair has become commonplace in recent years and has been used as evidence in legal proceedings. Despite the routine use of such toxicological analysis, the correct interpretation of alcohol biomarker hair testing can be complex, and there may be debate as to the significance of the data. Read More

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November 2018

Brexit fuels demand for BVA input at Westminster.

Authors:

Vet Rec 2018 Dec;183(21):667

As Brexit continues to dominate proceedings, Parliament has sought the expertise of the veterinary profession in an unprecedented way, says BVA Policy Officer . Read More

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December 2018

Assessing prognosis and prediction of treatment response in early rheumatoid arthritis: systematic reviews.

Health Technol Assess 2018 Nov;22(66):1-294

School of Health and Related Research (ScHARR), University of Sheffield, Sheffield, UK.

Background: Rheumatoid arthritis (RA) is a chronic, debilitating disease associated with reduced quality of life and substantial costs. It is unclear which tests and assessment tools allow the best assessment of prognosis in people with early RA and whether or not variables predict the response of patients to different drug treatments.

Objective: To systematically review evidence on the use of selected tests and assessment tools in patients with early RA (1) in the evaluation of a prognosis (review 1) and (2) as predictive markers of treatment response (review 2). Read More

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November 2018
1 Read

Proceedings from the 2018 Association for Chemoreception Annual Meeting Symposium: Bariatric Surgery and Its Effects on Taste and Food Selection.

Chem Senses 2018 Dec 4. Epub 2018 Dec 4.

Diabetes Complications Research Centre, University College Dublin, Dublin, Ireland.

This article provides a summary of the topics discussed at the symposium titled Bariatric Surgery and Its Effects on Taste and Food Selection which was held at the Fortieth Annual Meeting of the Association for Chemoreception Sciences. Bariatric surgery such as Roux-en-Y gastric bypass (RYGB) is currently one of the most effective treatments available for weight loss and Type-2 diabetes. For this reason, it is of great interest to clinicians as well as to basic scientists studying the controls of feeding and energy balance. Read More

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December 2018
2 Reads

Building capacity for advances in tuberculosis research; proceedings of the third RePORT international meeting.

Tuberculosis (Edinb) 2018 Dec 1;113:153-162. Epub 2018 Oct 1.

FHI 360 and Duke University, Durham, NC, USA. Electronic address:

RePORT International is a global network of research sites in India, Brazil, Indonesia, South Africa, China, and the Philippines dedicated to collaborative tuberculosis research in the context of HIV. A standardized research protocol (the Common Protocol) guides the enrollment of participants with active pulmonary tuberculosis and contacts into observational cohorts. The establishment of harmonized clinical data and bio-repositories will allow cutting-edge, large-scale advances in the understanding of tuberculosis, including identification of novel biomarkers for progression to active tuberculosis and relapse after treatment. Read More

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December 2018

Personalized Nutrition in Disrupting Cancer - Proceedings From the 2017 American College of Nutrition Annual Meeting.

J Am Coll Nutr 2018 Dec 4:1-14. Epub 2018 Dec 4.

o Weill Cornell Breast Center, Weill Cornell Medicine.

Cancer is a major public health problem and is the second leading cause of death in the United States and worldwide; nearly one in six deaths are attributable to cancer. Approximately 20% of all cancers diagnosed in the United States are attributable to unhealthy diet, excessive alcohol consumption, physical inactivity, and body fatness. Individual cancers are distinct disease states that are multifactorial in their causation, making them exceedingly cumbersome to study from a nutrition standpoint. Read More

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December 2018
1 Read

Targeting lifestyle energy expenditure in the management of obesity and health: from biology to built environment.

Obes Rev 2018 Dec;19 Suppl 1:3-7

Department of Endocrinology, Metabolism and Cardiovascular System, Faculty of Sciences and Medicine, University of Fribourg, Fribourg, Switzerland.

Increasing lifestyle energy expenditure has long been advocated in the prevention and treatment of obesity, as embodied in the ancient prescription of Hippocrates (the 'father of modern medicine') that people with obesity should eat less and exercise more. However, the long-term outcome of exercise alone or in combination with dieting in obesity management is poor. To understand the reasons underlying these failures and to develop novel strategies that target lifestyle energy expenditure in both prevention and treatment of obesity, research over the past decades has focused on (i) the interactions between physical activity and body weight (and its composition) throughout the lifespan; (ii) the influence of biology and potential compensatory changes in energy expenditure, food intake and food assimilation in response to energy deficits; and (iii) the impact of the built environment (outdoor and indoor) and smart technology on physical activity behaviours, thermoregulatory thermogenesis and metabolic health. Read More

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December 2018
2 Reads

Guidelines for exercise during normal pregnancy and gestational diabetes: a review of international recommendations.

Hormones (Athens) 2018 Dec 3. Epub 2018 Dec 3.

School of Physical Education and Sports Science, Democritus University of Thrace, 69100, Komotini, Greece.

Objective: Τo summarize and present the main guidelines for exercise during normal pregnancy and pregnancy complicated by gestational diabetes mellitus (GDM).

Methods: Relevant guidelines were retrieved through the electronic databases PubMed (MEDLINE), CENTRAL (Cochrane), and Embase; reference sections of the retrieved publications; proceedings of the main congresses in the field; and websites of relevant organizations published during the years 2000-2018.

Results: All guidelines recommend aerobic training from 60 to 150 min/week, with an upper limit of 30 min/day. Read More

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December 2018
2 Reads

Proceedings of the Third Freiburg Thrombosis Meeting.

Hamostaseologie 2018 Nov 30;38(4):183-185. Epub 2018 Nov 30.

Department of Cardiology and Angiology I, Heart Center, University of Freiburg, Freiburg, Germany.

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November 2018
2 Reads

Protocol for the systematic review of research on professional learning to promote implementation of a multitiered system of support in education.

BMJ Open 2018 Nov 28;8(11):e024057. Epub 2018 Nov 28.

Department of Educational and Psychological Studies, University of South Florida, Tampa, Florida, USA.

Introduction: A multitiered system of supports (MTSS) represents a widely adopted public health approach to education in the USA. Researchers agree professional learning is critical for educators to implement the critical components of MTSS; however, professional learning approaches vary in their designs and targeted outcomes. While researchers increasingly focus their inquiries on professional learning for MTSS, no systematic research review exists. Read More

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November 2018
1 Read

Prime time for immunotherapy in advanced urothelial cancer.

Asia Pac J Clin Oncol 2018 Nov;14 Suppl 5:24-32

Princess Margaret Cancer Centre, University Health Network, University of Toronto, Toronto, Ontario.

Background: Metastatic urothelial cancer (UC) is a lethal disease. Until 2016, cytotoxic chemotherapy with substantial toxicity was the only therapeutic option. In the first-line metastatic setting, cisplatin-based combination chemotherapy remains the standard of care. Read More

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November 2018
1 Read

SCAI 2018 Think Tank Proceedings: "What skillsets are required of vascular interventional cardiologists in evaluating and managing critical limb ischemia (CLI)? What role should SCAI play in supporting interventional cardiologists in their CLI practices, individually and collectively?"

Catheter Cardiovasc Interv 2018 Nov 29. Epub 2018 Nov 29.

Medtronic, Minneapolis, MN, USA.

The aim of this article is to discuss the poor outcomes associated with critical limb ischemia (CLI) and the required knowledge needed for optimal care. There is an opportunity for the Society for Cardiovascular Angiography and Interventions (SCAI) to assist interventional cardiologists in enhancing CLI care through creation of training standards and development of educational content. Read More

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November 2018
2.110 Impact Factor

Effects of peri-operative nonsteroidal anti-inflammatory drugs on post-operative kidney function for adults with normal kidney function.

Cochrane Database Syst Rev 2018 Nov 29;11:CD011274. Epub 2018 Nov 29.

Renal Unit, NHS Tayside, Ninewells Hospital, Dundee, UK, DD1 9SY.

Background: Nonsteroidal anti-inflammatory drugs (NSAIDs) provide effective analgesia during the post-operative period but can cause acute kidney injury (AKI) when used peri-operatively (at or around the time of surgery). This is an update of a Cochrane review published in 2007.

Objectives: This review looked at the effect of NSAIDs used in the peri-operative period on post-operative kidney function in patients with normal kidney function. Read More

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November 2018
2 Reads

Selected conference proceedings of the XIth Barcelona International Mediterranean Diet Conference.

Authors:

Eur J Clin Nutr 2018 Nov 28. Epub 2018 Nov 28.

April 27-28, 2016Barcelona, SpainOrganized by: Mediterranean Diet FoundationThis supplement is a selection of papers presented at the XI Barcelona International Mediterranean Diet Conference that took place in Barcelona, Spain on April 27-28, 2016 within the framework of the International Food and Beverage Exhibition, Alimentaria 2016. This conference discussed various aspects of achieving an even healthier lifestyle, taking into account that the Mediterranean Diet is regarded as a lifestyle as well as a dynamic food pattern.Sponsorship statement: This supplement is sponsored by the Mediterranean Diet Foundation and the Diputació de Barcelona. Read More

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November 2018

Laparoscopic versus open surgery for suspected appendicitis.

Cochrane Database Syst Rev 2018 11 28;11:CD001546. Epub 2018 Nov 28.

Institute for Research in Operative Medicine (IFOM) - Department for Evidence-based Health Services Research, University Witten/Herdecke, Ostmerheimer Str. 200 (Building 38), Cologne, Germany, 51109.

Background: The removal of the acute appendix is one of the most frequently performed surgical procedures. Open surgery associated with therapeutic efficacy has been the treatment of choice for acute appendicitis. However, in consequence of the evolution of endoscopic surgery, the operation can also be performed with minimally invasive surgery. Read More

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November 2018
1 Read

European perspective on the 2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer. Proceedings of an interactive international symposium.

Thyroid 2018 Nov 28. Epub 2018 Nov 28.

University Hospital Essen, Department of Endocrinology and Metabolism, and Division of Laboratory Research, Essen, Germany ;

Background: The American Thyroid Association (ATA) Management Guidelines for Patients with Thyroid Nodules and Differentiated Thyroid Cancer (DTC) are highly influential practice recommendations. The latest revision appeared in 2015 ("ATA 2015"). These guidelines were developed predominantly by North American experts. Read More

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November 2018
3 Reads

Oral isotretinoin for acne.

Cochrane Database Syst Rev 2018 Nov 24;11:CD009435. Epub 2018 Nov 24.

Emergency Medicine and Evidence Based Medicine, Universidade Federal de São Paulo, Rua Napoleão de Barros, 865, São Paulo, Sao Paulo, Brazil, 04024-002.

Background: Acne vulgaris, a chronic inflammatory disease of the pilosebaceous unit associated with socialisation and mental health problems, may affect more than 80% of teenagers. Isotretinoin is the only drug that targets all primary causal factors of acne; however, it may cause adverse effects.

Objectives: To assess efficacy and safety of oral isotretinoin for acne vulgaris. Read More

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November 2018

Baclofen for alcohol use disorder.

Cochrane Database Syst Rev 2018 Nov 26;11:CD012557. Epub 2018 Nov 26.

Department of Epidemiology, Lazio Regional Health Service, Via Cristoforo Colombo, 112, Rome, Italy, 00154.

Background: Alcohol use disorder (AUD) and alcohol-related impairments belong to the most widespread psychiatric disorders leading to specific psychophysical, affective and cognitive symptoms and consequences for psychosocial well-being and health. Alcohol consumption is increasingly becoming a problem in many developing regions and AUD prevalence is estimated at 4.1% worldwide, with highest prevalence in European countries (7. Read More

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November 2018
1 Read

PowerPlex® fusion 6C system: internal validation study.

Forensic Sci Res 2018 9;3(2):130-137. Epub 2018 Feb 9.

Forensic Genetic Service, Centre Branch, National Institute of Legal Medicine and Forensic Sciences,Coimbra, Portugal.

This work is aimed at describing the proceedings and parameters used to validate PowerPlex® Fusion 6C System, the polymerase chain reaction (PCR) amplification kit by Promega, for posterior implementation in the laboratorial routine of the Forensic Genetic Service. The PowerPlex® Fusion 6C System allows multiplex PCR, through simultaneous amplification and posterior detection by fluorescence of 27 loci. Characterization of the kit was made according to the laboratory's internal validation procedure based on validation guidelines from Scientific Working Group on DNA Analysis Methods. Read More

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February 2018

Women's experiences of a randomised controlled trial of a specialist psychological advocacy intervention following domestic violence: A nested qualitative study.

PLoS One 2018 27;13(11):e0193077. Epub 2018 Nov 27.

Centre for Academic Primary Health Care, Bristol Medical School, University of Bristol, Bristol, United Kingdom.

Background: Women's experience of domestic violence and abuse (DVA) is associated with mental illness which may not be addressed by domestic violence advocacy. The study aimed to compare the experiences of women receiving a psychological intervention with women receiving usual advocacy in a randomized controlled trial (PATH: Psychological Advocacy Towards Healing), to illuminate the trial results by exploring women's experiences of benefits and difficulties.

Methods: A qualitative study nested within the PATH trial, based in two DVA agencies in the UK. Read More

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November 2018
2 Reads

Anti-angiogenic therapy for high-grade glioma.

Cochrane Database Syst Rev 2018 11 22;11:CD008218. Epub 2018 Nov 22.

Medical Oncology, Alfred Hospital, Commercial Road, Melbourne, Victoria, Australia, 3004.

Background: This is an updated version of the original Cochrane Review published in September 2014. The most common primary brain tumours in adults are gliomas. Gliomas span a spectrum from low to high grade and are graded pathologically on a scale of one to four according to the World Health Organization (WHO) classification. Read More

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November 2018
2 Reads