53,134 results match your criteria Proceedings of the Institution of Mechanical Engineers. Part H Journal of engineering in medicine[Journal]


Use of Immunosuppressive therapy for management of myelodysplastic syndromes: a systematic review and meta-analysis.

Haematologica 2019 Apr 19. Epub 2019 Apr 19.

Department of Internal Medicine, Section of Hematology, Yale School of Medicine;

Immunosuppressive therapy is one therapy option for treatment of patients with lower-risk myelodysplastic syndromes. However, the use of several different immunosuppressive regimens, the lack of high-quality studies, and the absence of validated predictive biomarkers pose important challenges. We conducted a systematic review and meta-analysis according to the Meta-Analysis of Observational Studies in Epidemiology (MOOSE) guidelines and searched MEDLINE via PubMed, Ovid EMBASE, COCHRANE registry of clinical trials (CENTRAL), and the Web of Science without language restriction from inception through September 2018 as well as relevant conference proceedings and abstracts. Read More

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http://dx.doi.org/10.3324/haematol.2019.219345DOI Listing

Rapidly decreasing prevalence of Helicobacter pylori among Japanese children and adolescents.

J Infect Chemother 2019 Apr 16. Epub 2019 Apr 16.

Department of Public Health, Aichi Medical University School of Medicine, Japan. Electronic address:

Background: The secular trend in the prevalence of Helicobacter pylori (H. pylori) infection among children and adolescents in Japan has not been well documented.

Materials And Methods: We reviewed all relevant literature published between 1991 and 2017, focusing on the relationship between the prevalence of H. Read More

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http://dx.doi.org/10.1016/j.jiac.2019.02.016DOI Listing

Recent Advances on Metal-Free, Visible-Light- Induced Catalysis for Assembling Nitrogen- and Oxygen-Based Heterocyclic Scaffolds.

Molecules 2019 Apr 18;24(8). Epub 2019 Apr 18.

Institute of Organic Chemistry Polish Academy of Sciences, Kasprzaka 44/52, 01-224 Warsaw, Poland.

Heterocycles are important class of structures, which occupy a major space in the domain of natural and bioactive compounds. For this reason, development of new synthetic strategies for their controllable synthesis became of special interests. The development of novel photoredox systems with wide-range application in organic synthesis is particularly interesting. Read More

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http://dx.doi.org/10.3390/molecules24081533DOI Listing

The Impact of a Sparse Migration Topology on the Runtime of Island Models in Dynamic Optimization.

Algorithmica 2018 20;80(5):1634-1657. Epub 2017 Sep 20.

2DTU Compute, Technical University of Denmark, Kongens Lyngby, Denmark.

Island models denote a distributed system of evolutionary algorithms which operate independently, but occasionally share their solutions with each other along the so-called migration topology. We investigate the impact of the migration topology by introducing a simplified island model with behavior similar to islands optimizing the so-called Maze fitness function (Kötzing and Molter in Proceedings of parallel problem solving from nature (PPSN XII), Springer, Berlin, pp 113-122, 2012). Previous work has shown that when a complete migration topology is used, migration must not occur too frequently, nor too soon before the optimum changes, to track the optimum of the Maze function. Read More

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http://dx.doi.org/10.1007/s00453-017-0377-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438647PMC
September 2017

Interdisciplinary collaboration needed in obtaining high-quality medical information in child abuse investigations.

Child Abuse Negl 2019 Apr 15;92:167-178. Epub 2019 Apr 15.

Medical College of Wisconsin, 8701 W. Watertown Plank Rd., Wauwatosa, WI, 53226, USA.

Background: Despite reporting legislation, healthcare providers (HCPs) do not always report and collaborate in cases of suspected child abuse. Recognizing this leaves children at risk, the Wisconsin Child Abuse Network (WI CAN) sought to understand barriers to mandated reporting and collaboration with child abuse investigators.

Objective: The purpose of the study was to investigate barriers for professionals in providing and obtaining high-quality medical information in child abuse investigations. Read More

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http://dx.doi.org/10.1016/j.chiabu.2019.02.012DOI Listing

Strange Bedfellows: Native American Tribes, Big Pharma, and the Legitimacy of Their Alliance.

Authors:
Daniel C Kennedy

Duke Law J 2019 Apr;68(7):1433-68

Lost in the cacophony surrounding the debate about high drug prices is the fundamental principle that pharmaceutical innovation will not occur without the prospect of outsized returns enabled through market exclusivity. Biopharmaceutical patents are currently under siege, subject to challenge both in inter partes review ("IPR") proceedings and in Hatch-Waxman actions. These twin assaults threaten to eliminate the incentives necessary for biotechnological innovation--particularly for discoveries made upstream in the innovation pipeline--thus imperiling the development of new drug therapies. Read More

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Screening hysteroscopy in subfertile women and women undergoing assisted reproduction.

Cochrane Database Syst Rev 2019 Apr 16;4:CD012856. Epub 2019 Apr 16.

Department of Reproductive Medicine, Christian Medical College, Ida Scudder Road, Vellore, Tamil Nadu, India, 632004.

Background: Screening hysteroscopy in infertile women with unexplained infertility, or prior to intrauterine insemination (IUI) or in vitro fertilisation (IVF) may reveal intrauterine pathology that may not be detected by routine transvaginal ultrasound. Hysteroscopy, whether purely diagnostic or operative may improve reproductive outcomes.

Objectives: To assess the effectiveness and safety of screening hysteroscopy in subfertile women undergoing evaluation for infertility, and subfertile women undergoing IUI or IVF. Read More

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http://dx.doi.org/10.1002/14651858.CD012856.pub2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472583PMC
April 2019
2 Reads

Proceedings of the First Workshop Organized by the IAFSS Working Group on Measurement and Computation of Fire Phenomena (MaCFP).

Fire Saf J 2018 ;101

Department of Mechanical and Mechatronics Engineering, University of Waterloo,Waterloo, Ontario, N2L 3G1, Canada.

This paper provides a report of the discussions held at the first workshop on Measurement and Computation of Fire Phenomena (MaCFP) on June 10-11 2017. The first MaCFP work-shop was both a technical meeting for the gas phase subgroup and a planning meeting for the condensed phase subgroup. The gas phase subgroup reported on a first suite of experimental- computational comparisons corresponding to an initial list of target experiments. Read More

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http://dx.doi.org/10.1016/j.firesaf.2018.08.009DOI Listing
January 2018

Hepatic late adverse effects after antineoplastic treatment for childhood cancer.

Cochrane Database Syst Rev 2019 Apr 15;4:CD008205. Epub 2019 Apr 15.

Department of Paediatric Oncology, Emma Children's Hospital, Amsterdam UMC, University of Amsterdam, PO Box 22660, Amsterdam, Netherlands, 1100 DD.

Background: Survival rates have greatly improved as a result of more effective treatments for childhood cancer. Unfortunately, the improved prognosis has been accompanied by the occurrence of late, treatment-related complications. Liver complications are common during and soon after treatment for childhood cancer. Read More

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http://doi.wiley.com/10.1002/14651858.CD008205.pub3
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http://dx.doi.org/10.1002/14651858.CD008205.pub3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463806PMC
April 2019
3 Reads

Psychiatrist in Court: Indian Scenario.

Indian J Psychol Med 2019 Mar-Apr;41(2):126-132

Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bengaluru, Karnataka, India.

The impetus for practical exposure to legalities that arise in the context of psychiatry and law is minimal in postgraduate training in psychiatry and curriculum. Those who choose to get trained often do not get first-hand exposure to court proceedings. Law and psychiatry often come into each other's interface, and psychiatry is regulated by the legal system more often than the other specialties in medicine. Read More

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http://dx.doi.org/10.4103/IJPSYM.IJPSYM_53_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436416PMC

Adjuvant therapy with antidepressants for the management of inflammatory bowel disease.

Cochrane Database Syst Rev 2019 Apr 12;4:CD012680. Epub 2019 Apr 12.

School of Psychology, Deakin University Geelong, 221 Burwood Highway, Burwood, VIC, Victoria, Australia, 3025.

Background: Symptoms of anxiety and depression are common in inflammatory bowel disease (IBD). Antidepressants are taken by approximately 30% of people with IBD. However, there are no current guidelines on treating co-morbid anxiety and depression in people with IBD with antidepressants, nor are there clear data on the role of antidepressants in managing physical symptoms of IBD. Read More

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http://doi.wiley.com/10.1002/14651858.CD012680.pub2
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http://dx.doi.org/10.1002/14651858.CD012680.pub2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6459769PMC
April 2019
2 Reads

Bootstrapping variables in algebraic circuits.

Proc Natl Acad Sci U S A 2019 Apr 11. Epub 2019 Apr 11.

Department of Computer Science & Engineering, Indian Institute of Technology Kanpur, Kanpur 208016, India

We show that for the blackbox polynomial identity testing (PIT) problem it suffices to study circuits that depend only on the first extremely few variables. One needs only to consider size-s degree-s circuits that depend on the first [Formula: see text] variables (where c is a constant and composes a logarithm with itself c times). Thus, the hitting-set generator (hsg) manifests a bootstrapping behavior-a partial hsg against very few variables can be efficiently grown to a complete hsg. Read More

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http://dx.doi.org/10.1073/pnas.1901272116DOI Listing

Patients' and health professionals' attitudes and perceptions towards the initiation of preventive drugs for primary prevention of cardiovascular disease: protocol for a systematic review of qualitative studies.

BMJ Open 2019 Apr 11;9(4):e025587. Epub 2019 Apr 11.

Institute of Applied Health Research, University of Birmingham, Birmingham, West Midlands, UK.

Introduction: Lipid-lowering drugs and antihypertensive agents can be prescribed for the primary prevention of cardiovascular disease. In some cases, patients eligible for primary prevention of cardiovascular disease according to the European guidelines are not always started on preventive drugs. Existing research explores the attitudes of health professionals and patients towards cardiovascular preventive drugs but does not always differentiate between the attitudes towards drug initiation for primary or secondary prevention. Read More

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http://dx.doi.org/10.1136/bmjopen-2018-025587DOI Listing

Community-based antibiotic delivery for possible serious bacterial infections in neonates in low- and middle-income countries.

Cochrane Database Syst Rev 2019 Apr 11;4:CD007646. Epub 2019 Apr 11.

Division of Neonatology, University of Toronto, Toronto, Canada.

Background: The recommended management for neonates with a possible serious bacterial infection (PSBI) is hospitalisation and treatment with intravenous antibiotics, such as ampicillin plus gentamicin. However, hospitalisation is often not feasible for neonates in low- and middle-income countries (LMICs). Therefore, alternative options for the management of neonatal PSBI in LMICs needs to be evaluated. Read More

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http://dx.doi.org/10.1002/14651858.CD007646.pub3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458055PMC
April 2019
2 Reads

Venetoclax in the treatment of chronic lymphocytic leukemia.

Expert Opin Drug Metab Toxicol 2019 Apr 10. Epub 2019 Apr 10.

a Department of Hematology , Medical University of Lodz , 93-510 Lodz, Ciolkowskiego 2, Poland.

Introduction: Venetoclax, an antagonist of BCL-2 protein plays an important role in the pathogenesis of chronic lymphocytic leukemia (CLL). It has been approved by the FDA for the treatment of relapsed/refractory CLL with del17p, and by the EMA for patients with del17p/TP53 mutation who have failed a BCR inhibitor, or in patients without those aberrations who have failed previous therapy, regardless of their genetic/molecular profile. Venetoclax in combination with rituximab has been also approved for the treatment of CLL after at least 1 prior therapy, regardless of del17p. Read More

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http://dx.doi.org/10.1080/17425255.2019.1606211DOI Listing
April 2019
1 Read

Can the development of fusion energy be accelerated? An introduction to the proceedings.

Authors:
Colin Windsor

Philos Trans A Math Phys Eng Sci 2019 Mar;377(2141):20170446

Tokamak Energy Ltd , 173 Brook Drive, Milton Park OX14 4SD , UK.

This introduction reviews the unique opportunity of fusion power to deliver safe, carbon-free, abundant, base-load power. The differences from fission power are considered: especially why a Chernobyl, Three Mile Island or Fukushima accident could not happen with a fusion reactor. The Lawson triple product is introduced, along with tokamaks, or magnetic bottles, whose ability to approach close to the fusion burn conditions has so far put them above their competitors. Read More

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http://www.royalsocietypublishing.org/doi/10.1098/rsta.2017.
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http://dx.doi.org/10.1098/rsta.2017.0446DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365849PMC
March 2019
1 Read

Proceedings B 2018: the year in review.

Proc Biol Sci 2019 Jan;286(1894):20182590

Editor-in-Chief.

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http://dx.doi.org/10.1098/rspb.2018.2590DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367163PMC
January 2019

The effect of neoadjuvant platinum-based chemotherapy in mutated triple negative breast cancers -systematic review and meta-analysis.

Hered Cancer Clin Pract 2019 25;17:11. Epub 2019 Mar 25.

4Centre for Fertility Preservation, Human Reproduction Department, Coimbra Hospital and University Centre (CHUC), EPE, Praceta Prof. Mota Pinto, 3000-075 Coimbra, Portugal.

Background: Triple negative breast cancers (TNBC) are associated with an aggressive clinical course, earlier recurrence and short survival. - mutated tumours represent up to 25% of all TNBC. status is being studied as a predictive biomarker of response to platinum agents. Read More

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https://hccpjournal.biomedcentral.com/articles/10.1186/s1305
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http://dx.doi.org/10.1186/s13053-019-0111-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434625PMC
March 2019
4 Reads

Non-antistreptococcal interventions for acute guttate psoriasis or an acute guttate flare of chronic psoriasis.

Cochrane Database Syst Rev 2019 Apr 8;4:CD011541. Epub 2019 Apr 8.

Department of Dermatology, Université François-Rabelais de Tours, Tours, France, 37044.

Background: Guttate psoriasis displays distinctive epidemiological and clinical features, making it a separate entity within the heterogeneous group of cutaneous psoriasis types. It is associated with genetic, immune, and environmental factors (such as stress and infections) and usually arises in younger age groups (including children, teenagers, and young adults). There is currently no cure for psoriasis, but various treatments can help to relieve the symptoms and signs. Read More

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http://dx.doi.org/10.1002/14651858.CD011541.pub2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6452774PMC

Povidone-iodine 1% is the most effective vaginal antiseptic for preventing post-cesarean endometritis: A systematic review and network meta-analysis.

Am J Obstet Gynecol 2019 Apr 4. Epub 2019 Apr 4.

University of Florida College of Medicine-Jacksonville Department of Obstetrics and Gynecology.

Background: Direct comparison meta-analyses have reported benefits with pre-surgical vaginal preparation prior to cesarean delivery for the reduction of endometritis. These reports did not perform a multi-treatment comparison of the various antiseptic solutions assessed in prior studies.

Objective: To systematically review the literature and indirectly quantitate and summarize the comparative efficacy of antiseptic formulations and their concentrations employed for preparation of the vagina prior to cesarean delivery in preventing endometritis and other infectious complications. Read More

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http://dx.doi.org/10.1016/j.ajog.2019.04.002DOI Listing
April 2019
1 Read

Physical activity for lower urinary tract symptoms secondary to benign prostatic obstruction.

Cochrane Database Syst Rev 2019 Apr 6;4:CD012044. Epub 2019 Apr 6.

Postgraduate Program on Society, Technology and Public Policies (SOTEPP); Department of Medicine, Centro Universitário Tiradentes (UNIT/AL), Av. Comendador Gustavo Paiva, 5017, Cruz das Almas, Maceió, AL, Brazil, 57038-000.

Background: Lower urinary tract symptoms caused by benign prostatic obstruction (LUTS/BPO) represents one of the most common clinical complaints in men. Physical activity might represent a viable first-line intervention for treating LUTS/BPO.

Objectives: To assess the effects of physical activity for lower urinary tract symptoms caused by benign prostatic obstruction (LUTS/BPO). Read More

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http://dx.doi.org/10.1002/14651858.CD012044.pub2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450803PMC
April 2019
2 Reads

Wading and Wandering and Swooping and Swirling by Lisa Houck.

Authors:
Margaret R Wentz

Mayo Clin Proc 2019 Apr;94(4):e57

Recognizing the contribution art has had in the Mayo Clinic environment since the original Mayo Clinic Building was finished in 1914, Mayo Clinic Proceedings features some of the numerous works of art displayed throughout the buildings and grounds on Mayo Clinic campuses as interpreted by the author. Read More

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http://dx.doi.org/10.1016/j.mayocp.2019.01.027DOI Listing

A Lexicon of Concepts of Humanistic Medicine: Exploring Different Meanings of Caring and Compassion at One Organization.

Acad Med 2019 Apr 2. Epub 2019 Apr 2.

E. Stergiopoulos is a fourth-year medical student, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada. R.H. Ellaway is professor, Department of Community Health Sciences, and director, Office of Health & Medical Education Scholarship, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada; ORCID: https://orcid.org/0000-0002-3759-6624. N. Nahiddi is a resident, Department of Psychiatry, Faculty of Medicine, McGill University, Montreal, Québec, Canada. M.A. Martimianakis is associate professor and director, Medical Education Scholarship, Department of Paediatrics, and scientist and associate director International and Partnerships, The Wilson Centre, Faculty of Medicine University of Toronto, Toronto, Ontario, Canada; ORCID: https://orcid.org/0000-0002-2531-3156.

Purpose: There has been scant scholarly attention paid to characterizing how the numerous definitions of terms associated with compassion and humanism have been mobilized or what the organizational implications of pursuing different constructs might be. This study explored the uses and implications of the terminology associated with humanistic medicine in the work of the Associated Medical Services (AMS) Phoenix Project.

Method: This study involved two phases (2014-2015). Read More

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http://dx.doi.org/10.1097/ACM.0000000000002732DOI Listing
April 2019
1 Read

Early histological changes of pulmonary arterial hypertension disclosed by invasive cardiopulmonary exercise testing.

Pulm Circ 2019 Apr-Jun;9(2):2045894019845615

1 Adult Centre for Pulmonary Hypertension, Royal Brompton Hospital, London, UK.

Early diagnosis of pulmonary artery hypertension (PAH) is diagnostically challenging given the extent of pulmonary vascular remodeling required to bring about clinical signs and symptoms. Exercise testing can be invaluable in this setting, as stressing the cardiopulmonary system may unmask early disease. This report describes a young patient with a positive family history of PAH in whom contemporaneous invasive cardiopulmonary exercise testing and surgical lung biopsy reveal the novel association between exercise pulmonary hypertension (ePH) and early histological changes of PAH. Read More

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http://dx.doi.org/10.1177/2045894019845615DOI Listing
April 2019
1 Read

Information-Theoretic Inference of an Optimal Dictionary of Protein Supersecondary Structures.

Methods Mol Biol 2019 ;1958:123-131

Department of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, PA, USA.

We recently developed an unsupervised Bayesian inference methodology to automatically infer a dictionary of protein supersecondary structures (Subramanian et al., IEEE data compression conference proceedings (DCC), 340-349, 2017). Specifically, this methodology uses the information-theoretic framework of minimum message length (MML) criterion for hypothesis selection (Wallace, Statistical and inductive inference by minimum message length, Springer Science & Business Media, New York, 2005). Read More

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http://dx.doi.org/10.1007/978-1-4939-9161-7_6DOI Listing
January 2019

Sometimes a stick might just be a stick.

Learn Behav 2019 Apr 3. Epub 2019 Apr 3.

Department of Psychology, University of Alberta, Edmonton, Alberta, Canada.

Suzuki (Proceedings of the Natural Academy of Sciences, 115, 1541-1545, 2018) conducted elegant field experiments examining referential communication in Japanese tits. Bond (Learning & Behavior, in press, 2019) explains some key considerations and future experimentation that should be conducted to solidify these conclusions. An important takeaway from both Suzuki and Bond is that scientists can, and should, both be excited for new, interesting scientific discoveries, and also view such findings with a critical, but collegial, eye for more parsimonious explanations and the manipulations required to test such explanations. Read More

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http://dx.doi.org/10.3758/s13420-019-00378-5DOI Listing
April 2019
1 Read

The Comparative Effectiveness of Mobile Phone Interventions in Improving Health Outcomes: Meta-Analytic Review.

JMIR Mhealth Uhealth 2019 Apr 3;7(4):e11244. Epub 2019 Apr 3.

Department of Communication and Media, University of Missouri-St. Louis, St. Louis, MO, United States.

Background: As mobile technology continues expanding, researchers have been using mobile phones to conduct health interventions (mobile health-mHealth-interventions). The multiple features of mobile phones offer great opportunities to disseminate large-scale, cost-efficient, and tailored messages to participants. However, the interventions to date have shown mixed results, with a large variance of effect sizes (Cohen d=-0. Read More

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http://dx.doi.org/10.2196/11244DOI Listing

Radix Sophorae flavescentis versus no intervention or placebo for chronic hepatitis B.

Cochrane Database Syst Rev 2019 Apr 3;4:CD013089. Epub 2019 Apr 3.

Centre for Evidence-Based Chinese Medicine, Beijing University of Chinese Medicine, Bei San Huan Dong Lu 11, Chaoyang District, Beijing, China, 100029.

Background: Hepatitis B virus (HBV) infection, a liver disease caused by hepatitis B virus, may lead to serious complications such as cirrhosis and hepatocellular carcinoma. People with HBV infection may have co-infections including HIV and other hepatitis viruses (hepatitis C or D), and co-infection may increase the risk of all-cause mortality. Chronic HBV infection increases morbidity and psychological stress and is an economic burden on people with chronic hepatitis B and their families. Read More

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http://dx.doi.org/10.1002/14651858.CD013089.pub2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446139PMC
April 2019
4 Reads

Entomopathogenic nematology in Latin America: A brief history, current research and future prospects.

J Invertebr Pathol 2019 Mar 30. Epub 2019 Mar 30.

Department of Entomology, University of Arizona, Forbes Bldg., Room 410, 1140 E. South Campus Dr., Tucson, AZ 85721-0036, USA.

Since the 1980s, research into entomopathogenic nematodes (EPNs) in Latin America has produced many remarkable discoveries. In fact, 16 out of the 117 recognized species of EPNs have been recovered and described in the subcontinent, with many more endemic species and/or strains remaining to be discovered and identified. In addition, from an applied perspective, numerous technological innovations have been accomplished in relation to their implementation in biocontrol. Read More

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http://dx.doi.org/10.1016/j.jip.2019.03.010DOI Listing
March 2019
1 Read
2.110 Impact Factor

The Israel Family Court - Therapeutic jurisprudence and jurisprudential therapy from the start.

Authors:
Philip Marcus

Int J Law Psychiatry 2019 Mar - Apr;63:68-75. Epub 2018 Jul 7.

Jerusalem Family Court, Israel. Electronic address:

Based on the recommendations of a commission set up to review the handling of Family Law cases in Israel, the Family Courts Law 5755-1995 included a revolutionary provision - that a Social Services Unit, staffed by senior social workers, would be an integral part of each Family Court. Their mandate includes giving assessment, advice and assistance services to litigants and to the court, and this provision has been broadly interpreted, to include mediation and referrals for therapy. The activities of the Unit are confidential and free of charge to the parties. Read More

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http://dx.doi.org/10.1016/j.ijlp.2018.06.006DOI Listing
July 2018
1 Read

Task Force on Design and Analysis in Oral Health Research: Medication-Related Osteonecrosis of the Jaw.

JDR Clin Trans Res 2018 Jul 12;3(3):222-225. Epub 2018 Apr 12.

7 Division of Periodontology, UConn Health, Farmington, CT, USA.

Knowledge Transfer Statement: This article discusses the proceedings of the conference organized by the Task Force on Design and Analysis in Oral Health Research on the understanding of the translational evidence on the etiology and pathogenesis of medication-related osteonecrosis of the jaw as well as the clinical protocols on patient management. Read More

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http://dx.doi.org/10.1177/2380084418770662DOI Listing
July 2018
8 Reads

International review of sexual behaviour assessment labs.

Int Rev Psychiatry 2019 Apr 2:1-12. Epub 2019 Apr 2.

b Sexual Behaviours Clinic, Integrated Forensic Program , The Royal , Ottawa , ON , Canada.

This article provides a comparison and comprehensive analysis of varied approaches to the assessment of sexual interest and behaviours at different international sexual behaviour assessment labs. The assessment protocols are described for four sexual behaviour laboratories: the Royal Ottawa Mental Health Centre's Sexual Behaviours Clinic in Canada; the Medical University of South Carolina's Sexual Behaviours Clinic and Laboratory in the US; the Laboratory of Evolutionary Sexology and Psychopathology in the Czech Republic; and the Laboratory of Forensic Sexology in Russia. An overview of examinee demographics and types of cases assessed is provided for each lab. Read More

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http://dx.doi.org/10.1080/09540261.2018.1559135DOI Listing
April 2019
1 Read

Meeting report: 32nd international mammalian genome conference.

Mamm Genome 2019 Apr 1. Epub 2019 Apr 1.

The Jackson Laboratory, 600 Main Street, Bar Harbor, ME, 04609, USA.

Over 150 scientists from more than 50 research institutions and eight countries attended the 32nd annual meeting of the International Mammalian Genome Society (IMGS) held in Rio Mar, Puerto Rico. Attendees included predoctoral and postdoctoral trainees, junior investigators, clinicians, industry professionals, and established leaders in mammalian genetics and genomics. From November 11-14, major scientific advances in the fields of systems genetics, developmental biology, cancer, human disease modeling, and bioinformatics were showcased in a series of 66 poster and 54 platform presentations. Read More

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http://dx.doi.org/10.1007/s00335-019-09797-1DOI Listing

Hybrid graft vs autograft in anterior cruciate ligament reconstruction: a meta-analysis.

Ther Clin Risk Manag 2019 14;15:487-495. Epub 2019 Mar 14.

Department of Joint Surgery, Tianjin Hospital, Tianjin, People's Republic of China,

Purpose: We conducted this meta-analysis to evaluate the efficacy of hybrid grafts in anterior cruciate ligament reconstruction (ACLR).

Methods: We performed an electronic search of the Cochrane Library, PubMed, Embase, and ScienceDirect from the inception of these databases to February 2018, based on the terms "anterior cruciate ligament or ACL reconstruction", "autograft", "hybrid", and "augment". Relevant journals and conference proceedings were searched manually. Read More

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http://dx.doi.org/10.2147/TCRM.S187979DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422411PMC
March 2019
3 Reads
1.343 Impact Factor

Long-term antibiotics for preventing recurrent urinary tract infection in children.

Cochrane Database Syst Rev 2019 Apr 1;4:CD001534. Epub 2019 Apr 1.

Centre for Kidney Research, The Children's Hospital at Westmead, Locked Bag 4001, Westmead, NSW, Australia, 2145.

Background: Urinary tract infection (UTI) is common in children. Symptoms include fever, lethargy, anorexia, and vomiting. UTI is caused by Escherichia coli in over 80% of cases and treatment is a course of antibiotics. Read More

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http://dx.doi.org/10.1002/14651858.CD001534.pub4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442022PMC
April 2019
3 Reads

Informed consent in spinal surgery.

Authors:
N V Todd N C Birch

Bone Joint J 2019 Apr;101-B(4):355-360

The Chris Moody Rehabilitation and Sports Injury Centre, Moulton, UK.

Informed consent is a very important part of surgical treatment. In this paper, we report a number of legal judgements in spinal surgery where there was no criticism of the surgical procedure itself. The fault that was identified was a failure to inform the patient of alternatives to, and material risks of, surgery, or overemphasizing the benefits of surgery. Read More

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http://dx.doi.org/10.1302/0301-620X.101B4.BJJ-2018-1045.R2DOI Listing

Proceedings of the Inaugural Strategy Meeting for the Establishment of a Southeast Asia (SEA) Regional Therapeutic Plasma Exchange (TPE) Consortium for Neurological Disorders.

Ther Apher Dial 2019 Mar 30. Epub 2019 Mar 30.

Department of Neurology, Kuala Lumpur Hospital, Kuala Lumpur, Malaysia.

In conjunction with the 3 regional Southeast Asian (SEA) therapeutic plasma exchange (TPE) conference in Kuala Lumpur, Malaysia, 25 clinicians and researchers from SEA and South Asian countries attended the inaugural strategy meeting for the establishment of a regional TPE consortium for neurological disorders. The primary objective was to establish regional collaboration to improve delivery of TPE services in SEA. A pre-meeting survey was conducted to gather insights on disease spectrum, contextual practice challenges and the need for a regional TPE consensus. Read More

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http://dx.doi.org/10.1111/1744-9987.12806DOI Listing
March 2019
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Quality insurance in head and neck cancer multidisciplinary team meetings: A watchful eye on real-life experience.

Oral Oncol 2019 Apr 26;91:35-38. Epub 2019 Feb 26.

Department of Radiotherapy, Lucien Neuwirth Cancer Institute, Saint-Priest en Jarez, France. Electronic address:

Introduction: Although Multidisciplinary Team Management (MDT) is integrated in most international head and neck cancer treatment guidelines, its applications and proceedings were rarely described. The present study explores a 6-year real-life experience in a French Comprehensive Cancer Care Center.

Methods: Patients, tumor and meeting characteristics of all consecutive cases discussed in head and neck MDT meetings between 2010 and 2015 were retrospectively reviewed. Read More

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http://dx.doi.org/10.1016/j.oraloncology.2019.02.020DOI Listing