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Procedia Vaccinol 2015;9:16-23

University of Maryland School of Medicine, USA.

A safe, effective, and inexpensive vaccine against typhoid and other diseases is urgently needed. In order to address this need, we are developing a novel vaccine platform employing buoyant, self-adjuvanting gas vesicle nanoparticles (GVNPs) from the halophilic archaeon sp. NRC-1, bioengineered to display highly conserved antigens. Read More

Procedia Vaccinol 2014 Jan;8:38-42

Tulane University School of Medicine, New Orleans LA 70112, USA.

()is the causative agent of melioidosis and is endemic in regions of northern Australia and Southeast Asia. is inherently resistant to multiple antibiotics and is considered a potential biological warfare agent by the U.S. Read More

Procedia Vaccinol 2010 ;2(1)

Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, Texas 77555-1070 ; Department of Pathology, University of Texas Medical Branch, Galveston, Texas 77555-1070 ; The Sealy Center for Vaccine Development, University of Texas Medical Branch, Galveston, Texas 77555-1070.

and are Gram-negative pathogenic bacteria, responsible for the diseases glanders and melioidosis, respectively. Furthermore, there is currently no vaccine available against these species. In this study, we aimed to identify protective proteins against these pathogens. Read More

Procedia Vaccinol 2010 ;3:12-18

Department of Biomedical Sciences, College of Medicine, University of Illinois Rockford, 1601 Parkview Avenue, Rockford, Illinois, USA. 61107.

Lymphatic filariasis is a mosquito borne parasitic infection that cause severe economic burden in several parts of the world. Currently there is no vaccine available to prevent this infection in human. Multidrug therapy is effective, however, requires annual treatment and there is significant concern of drug resistance. Read More

Procedia Vaccinol 2010 ;2(1):15-19

School of Chemical and Biomolecular Engineering, Georgia Institute of Technology.

Morbidity and mortality due to seasonal and pandemic influenza could be reduced by simpler vaccination methods that enable improved vaccination coverage. In this study, solid metal microneedles coated with influenza virus-like particle (VLP) vaccine were inserted into skin for intradermal immunization. Microneedles were applied to the skin by hand and designed for simple administration with little or no training. Read More