Search Our Scientific Publications & Authors

Restor Dent Endod 2022 May 4;47(2):e17. Epub 2022 Mar 4.

Department of Endodontics, Faculdade de Medicina Dentária, Universidade de Lisboa, Lisboa, Portugal.

Endodontic microsurgery is a predictable treatment option when orthograde treatment or retreatment is unsuccessful or unfeasible. However, when there is a gross compromise of periapical bone, achievement of bone regeneration after the surgical procedure may be hampered. In such cases, the application of guided tissue regeneration principles, with adjunctive use of leukocyte platelet-rich fibrin to fill the bone defect as a bone substitute and as a membrane to cover the site, provides a cost-effective solution with the benefits of accelerated physiological healing and reduced post-surgical pain and discomfort. Read More

Plast Reconstr Surg 2022 Jun 9. Epub 2022 Jun 9.

Institute for Molecular and Cellular Anatomy, University of Regensburg, Regensburg, Germany.

Summary: Microsurgery and supermicrosurgery are surgical subdomains necessary for a large variety of surgical disciplines. So far, there is no training model for lymphatic surgery or perforator flap surgery and the most commonly used microsurgical training models are living animals. However, the ethical principles of replacement, refinement, and reduction (3R´s) of living animals for training purposes were implemented, highlighting the necessity of an animal-sparing microsurgical training model. Read More

J Plast Reconstr Aesthet Surg 2022 Feb 19. Epub 2022 Feb 19.

Division of Plastic Surgery, Mayo Clinic, Rochester, MN, USA.

Introduction: Our objective was to measure the impact of a basic microsurgery training course on trainees' confidence and workload in performing microsurgery.

Methods: A prospective study of participants in an accredited 5-day microsurgery course over a 3-month period. The confidence and workload of the participants were assessed after the first and final day. Read More

Micromachines (Basel) 2022 Mar 20;13(3). Epub 2022 Mar 20.

Laboratory of Microscale Green Chemical Process Intensification, School of Chemical Engineering and Technology, Xi'an Jiaotong University, 28 Xianning West Road, Xi'an 710049, China.

Microrobots can operate in tiny areas that traditional bulk robots cannot reach. The combination of acoustic actuation with microrobots extensively expands the application areas of microrobots due to their desirable miniaturization, flexibility, and biocompatibility features. Herein, an overview of the research and development of acoustics-actuated microrobots is provided. Read More

Mol Biol Cell 2022 May 2;33(6):ar61. Epub 2022 Mar 2.

Laboratory of Biology and Modeling of the Cell, Ecole Normale Supérieure de Lyon, CNRS, Inserm, UCBL, 69007 Lyon, France.

Cellular functions such as cell division are remarkably conserved across phyla. However, the evolutionary principles of cellular organization that drive them are less well explored. Thus, an essential question remains: to what extent do cellular parameters evolve without altering the basic functions they sustain? Here we have observed six different nematode species for which the mitotic spindle is positioned asymmetrically during the first embryonic division. Read More

Pharmaceutics 2022 Feb 14;14(2). Epub 2022 Feb 14.

Division of Reconstructive Microsurgery, Department of Plastic and Reconstructive Surgery, Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Taoyuan City 333, Taiwan.

Mechanically processed stromal vascular fraction (mSVF) is a promising source for regenerative purposes. To study the in vivo fate of the mSVF, we herein used a vascularized tissue engineering chamber that insulates the target mSVF from the surrounding environment. In contrast to previous models, we propose an arteriovenous (AV) shunt between saphenous vessels in rats without a venous graft. Read More

J Hand Surg Asian Pac Vol 2022 Feb 23;27(1):10-21. Epub 2022 Feb 23.

Department of Plastic, Hand and Reconstructive Microsurgery, Ganga Medical Center and Hospitals Pvt. Ltd., Coimbatore, Tamil Nadu, India.

The advent of nerve transfers has revolutionised the treatment of brachial plexus and peripheral nerve injuries of the upper extremity. Nerve transfers offer faster reinnervation of a denervated muscle by taking advantage of a donor nerve, branch or fascicle close to the recipient muscle. A number of considerations in respect of donor selection for nerve transfers underlie their success. Read More

World Neurosurg 2022 Apr 29;160:67. Epub 2022 Jan 29.

Departments of Neurosurgery and Interventional Neuroradiology, Rothschild Foundation Hospital, Paris, France.

Dural arteriovenous fistulas are rare acquired vascular lesions that represent 15% of the vascular malformations. While endovascular treatment has recently became the first line of treatment, microsurgical ligation may still be indicated in specific cases. We present the case of a 75-year-old patient who presented a progressive tetraparesis culminating in a spastic paraplegia and urinary retention. Read More

Int J Surg Case Rep 2022 Feb 17;91:106768. Epub 2022 Jan 17.

Mogadishu Somali Turkish Research and Training Hospital, Mogadishu, Somalia.

Introduction And Importance: Meat grinder injury to the hand is not a common case but can cause a wide spectrum of injuries that are difficult to treat. Management of meat grinder hand injuries is complex and should be based on a clear understanding of principles of wound management, fracture fixation, and soft-tissue reconstruction. To our knowledge, here we reported the first case of meat grinder hand injury faced by a practicing surgeon in an underdeveloped country (Somalia) with a Successful outcome. Read More

Plast Reconstr Surg Glob Open 2021 Dec 10;9(12):e3980. Epub 2021 Dec 10.

Department of Surgery, Division of Plastic Surgery, University of California San Diego, San Diego, Calif.

Background: Medical students receive limited exposure to the field of plastic surgery because most students will not rotate in plastic surgery, especially those at schools without dedicated plastic surgery residency programs. This study aimed to create and validate a plastic surgery learning module for medical students to dispel media-propagated myths and misrepresentation of the breadth of plastic surgery and equip students with referral-making capabilities.

Methods: The plastic surgery learning module was created using Articulate Storyline 360 (New York, N. Read More

Med Sci (Basel) 2021 11 13;9(4). Epub 2021 Nov 13.

Klinik für Plastische, Rekonstruktive und Ästhetische Chirurgie, Handchirurgie, Alfried Krupp Krankenhaus Essen, 45276 Essen, Germany.

Wounds and tissue defects of the hand and foot often lead to severe functional impairment of the affected extremity. Next to general principles of wound healing, special functional and anatomic considerations must be taken into account in the treatment of wounds in these anatomical regions to achieve a satisfactory reconstructive result. In this article, we outline the concept of wound healing and focus on the special aspects to be considered in wounds of the hand and foot. Read More

Zhonghua Yan Ke Za Zhi 2021 Nov;57(11):819-824

Intraocular foreign body injury, as a special type of eye trauma, threatens visual function seriously via mechanical damage and a series of pathological changes to the eyeball due to the presence of a foreign body in the eye. Recently, the diagnosis of intraocular foreign body injury has been distinctly improved attributing to the advancement of medical imaging technology. Moreover, the ophthalmic microsurgery technology has been promoted and popularized, especially the technology of vitrectomy, which enhances the success rate of intraocular foreign body removal remarkably. Read More

J Hand Surg Eur Vol 2022 01 5;47(1):31-39. Epub 2021 Nov 5.

Department of Hand Surgery, Yixing People's Hospital, Yixing, Wuxi, Jiangsu, China.

The current clinical methods of flexor tendon repair are remarkably different from those used 20 years ago. This article starts with a review of the current methods, followed by presentation of past experience and current status of six eminent hand surgery units from four continents/regions. Many units are using, or are moving toward using, the recent strong (multi-strand) core suture method together with a simpler peripheral suture. Read More

J Minim Access Surg 2021 Oct-Dec;17(4):490-494

Department of Surgery, Rabin Medical Center, Hasharon Hospital, Petach Tikva; Sackler School of Medicine, Tel-Aviv University, Tel Aviv, Israel.

Background: Transanal endoscopic microsurgery (TEM) is considered the procedure of choice for rectal adenomas non-amendable for endoscopic excision and for early rectal cancer. TEM may gain more importance in patients who are considered unfit for major surgery. The option of spinal anaesthesia may offer many advantages for patients undergoing TEM while maintaining the principles of complete tumour excision. Read More

Oper Orthop Traumatol 2021 Oct 13;33(5):377-383. Epub 2021 Sep 13.

Klinik für Plastische Chirurgie, Universitätsklinikum Basel (CH), Basel, Schweiz.

This review article presents the history, indications and techniques for the usual nerve transpositions in the upper extremities. By means of nerve transposition paralyzed muscles are reinnervated using dispensable donor motor axons. Many standard operations on the upper extremities are attributable to concepts of German-speaking surgeons and orthopedists. Read More

Urologiia 2021 09(4):106-113

Department of Urology of A.I. Evdokimov Moscow State University of Medicine and Dentistry, Moscow, Russia.

Patients with non-obstructive azoospermia (NOA), which accounts for up to 10-15% of all cases of male infertility, until recently could only become parents using donor sperm or through adoption. Modern technical capabilities of sperm extraction in combination with the use of assisted reproductive technologies, make it possible to effectively overcome infertility in this group of patients. A number of highly effective techniques have been proposed for spermatozoa retrieval. Read More

Oper Neurosurg (Hagerstown) 2021 10;21(5):E435

Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

Hemangioblastomas are benign vascular tumors that can be sporadic or multiple, as part of Von Hippel-Lindau disease. They develop at any level of the central nervous system, with a predilection for the dorsal medulla among brainstem locations. Radical resection of the solid portion of the tumor is the best treatment option. Read More

Neuro Endocrinol Lett 2021 May 4;42(2):70-80. Epub 2021 May 4.

Department of Orthopedics, the Second Affiliated Hospital of Southern Medical University, Guangzhou 51030, China.

Background: Sectional image of the peripheral nerves is a prerequisite for studying the morphological parameters of fascicular groups. Ultra-high precision MicroCT scan can explicitly display the internal morphology of physiological tissues. This study aimed to quantitatively measure the basic morphological parameters of fascicular groups of a peripheral nerve on MicroCT images, obtain the statistical principles and investigate the variation pattern of these morphological parameters during the process of fascicular group extension. Read More

World Neurosurg 2021 08 18;152:144-151. Epub 2021 Jun 18.

Deputy Rapporteur Arabian Board of Neurosurgery, Director Local Committee of Arabian Board of Neurosurgery/Iraq, College of Medicine, University of Baghdad, Salihyia, Baghdad, Iraq. Electronic address:

Background: Most microsurgical instrument designs concentrate on manipulating the targeted tissue more than the detailed design of the user's hand. Microergonomics is a new area of study on hand design in order to redesign the instruments in a better way for the surgeon's hand.

Methods: The article describes how the concept of microergonomics could improve the design of microinstruments. Read More

Microsurgery 2022 Feb 4;42(2):176-180. Epub 2021 Jun 4.

Department of Plastic Surgery, Norfolk and Norwich University Hospital, Norwich, United Kingdom.

When performing breast reconstruction, reduction of the contralateral breast is often required to achieve symmetry. The tissue that would otherwise be discarded from the reduced breast has been utilized as a free flap. This has the benefit of minimizing donor site morbidity, and combining the principles of "spare-part-surgery" and replacing "like-with-like. Read More

J Pers Med 2021 May 12;11(5). Epub 2021 May 12.

Division of Plastic and Reconstructive Surgery, Department of Medical and Surgical Sciences, Modena Policlinico Hospital, University of Modena and Reggio Emilia, 41124 Modena, Italy.

Breast cancer-related lymphedema (BCRL) represents a global healthcare issue affecting the emotional and life quality of breast cancer survivors significantly. The clinical presentation is characterized by swelling of the affected upper limb, that may be accompanied by atrophic skin findings, pain and recurrent cellulitis. Cardinal principles of lymphedema management are the use of complex decongestive therapy and patient education. Read More

Ann Thorac Surg 2022 02 27;113(2):e107-e110. Epub 2021 Apr 27.

Division of Cardiac Surgery, Royal Victoria Hospital, McGill University Health Centre, McGill University, Faculty of Medicine, Montreal, Quebec, Canada. Electronic address:

Intracardiac cement embolism after percutaneous vertebroplasty is a rare, but dangerous, complication, and guiding principles for its management are not well described. The management of this present case of intracardiac cement embolism offers insight to facilitate the treatment decision-making process in symptomatic patients requiring extraction. Read More

J Hand Surg Asian Pac Vol 2021 Jun;26(2):152-157

Department of Hand and Reconstructive Microsurgery, National University Health System, Singapore.

Upper extremity trauma is one of the most common types of injuries, accounting for 20 to 40 percent of injured patients presenting to the emergency department. In severe upper extremity injury, the likelihood of secondary procedures to improve function and resolve outstanding clinical problems is high. Secondary procedures are performed later than initial primary surgery, usually after wound healing and with a discernible time gap of days, weeks or occasionally longer. Read More

Clin Oral Investig 2021 Jul 29;25(7):4269-4280. Epub 2021 Apr 29.

Department of Periodontics and Oral Medicine, University of Michigan - School of Dentistry, 1011 North University Avenue, Ann Arbor, MI, USA.

Objectives: Microsurgical principles, techniques, and armamentarium have made significant contributions to the periodontal plastic surgery. The present meta-analysis aimed to investigate the overall efficacy of microsurgery on root coverage, and its clinical outcomes when compared to traditional macrosurgery.

Material And Methods: Electronic searches on PubMed, Embase, and CINAHL were used to retrieve prospective clinical trials. Read More

Fertil Steril 2021 06 27;115(6):1384-1392. Epub 2021 Apr 27.

Department of Urology, Northwestern University Feinberg School of Medicine, Chicago, Illinois. Electronic address:

The basic principles of vasal reconstruction have endured since their initial description over a century ago, yet the nuances and technical approaches have evolved. Prior to performing vasectomy reversal, the clinician should perform a focused history, physical and laboratory assessment, all of which are critical for patient counseling and preoperative planning. Operative success is contingent on appropriate intraoperative decision making and technical precision in completing a tension-free, watertight, and patent anastomosis. Read More

World Neurosurg 2021 08 27;152:152-153. Epub 2021 Apr 27.

Department of Neurosurgery, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, Arizona, USA. Electronic address:

Optic chiasm cavernous malformations (CMs) are rare. Patients with these CMs typically present with progressive vision loss and are treated via microsurgical resection. We present a middle-aged man with a CM of the optic chiasm and right optic nerve treated via microsurgical resection. Read More

Injury 2021 Dec 7;52(12):3616-3623. Epub 2021 Apr 7.

Department of Orthopaedic Surgery, Faculty of Medicine, University of Thessaly, 3 Panepistimiou St, Biopolis41500Larissa, Greece; Hand, Upper Extremity and Microsurgery Department, IASO Thessalias, Nikaia41500Larissa, Greece. Electronic address:

Introduction: Among various patterns of complex injuries of the wrist and forearm, "spaghetti wrist" refers to an extensive volar forearm laceration, in which several of the 12 tendons, 2 major nerves and 2 major arteries are transected, leading to lifelong disability and psychological, social and economic consequences. The aim of the study is to emphasize the keynote principles for the management of these injuries through retrospective review of a large group of patients treated by a team of experienced hand surgeons.

Material-methods: Data were retrospectively obtained for 61 patients (49 males and 12 females with average age of 34. Read More

Clin Plast Surg 2021 Apr 10;48(2):331-340. Epub 2021 Feb 10.

Department of Plastic, Reconstructive, Aesthetic and Hand Surgery, University Hospital Basel, Spitalstrasse 21, Basel CH-4031, Switzerland; Centre for Musculoskeletal Infections, University Hospital Basel, Spitalstrasse 21, Basel CH-4031, Switzerland. Electronic address:

Demand has increased for complex lower-extremity reconstruction in the steadily growing elderly patient group in many highly developed countries. Microsurgery is indispensable for soft tissue reconstruction and osseous consolidation salvaging leg function and preventing amputation, with its devastating consequences. Microvascular reconstruction can be performed successfully in specialized centers with low donor-site morbidity, minimal operative time, and comparably low complication rates. Read More

J Neurosurg 2021 Feb 5:1-10. Epub 2021 Feb 5.

1The Loyal and Edith Davis Neurosurgical Research Laboratory, Department of Neurosurgery, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, Arizona; and.

Transorbital surgery has gained recent notoriety because of its incorporation into endoscopic skull base surgery. The use of this surgical corridor has been pervasive throughout the 20th century. It has been utilized by multiple disciplines for both clinical and experimental purposes, although its historical origin is medically and ethically controversial. Read More

Nat Rev Urol 2021 03 11;18(3):160-169. Epub 2021 Jan 11.

The James Buchanan Brady Urological Institute and Department of Urology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

Poor ergonomics in the operating room can have detrimental effects on a surgeon's physical, psychological and economic well-being. This problem is of particular importance to urologists who are trained in nearly all operative approaches (open, laparoscopic, robotic-assisted, microscopic and endoscopic surgery), each with their own ergonomic considerations. The vast majority of urologists have experienced work-related musculoskeletal pain or injury at some point in their career, which can result in leaves of absence, medical and/or surgical treatment, burnout, changes of specialty and even early retirement. Read More