711 results match your criteria Primary Lung Tuberculosis Imaging


Inflammatory Syndrome as the Initial Manifestation of Retroperitoneal Tuberculosis in a Pregnant Woman.

Eur J Case Rep Intern Med 2018 26;5(7):000865. Epub 2018 Jul 26.

Division of Pulmonary Diseases, Department of Internal Medicine Specialties, University Hospitals of Geneva, Switzerland.

A 20-year-old asylum seeker presented with vomiting and left thigh pain, with a biological inflammatory syndrome. Pregnancy was diagnosed. Investigations revealed a pseudo-cystic, 20-cm-long retroperitoneal abscess, biopsy of which confirmed the diagnosis of tuberculosis. Read More

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http://dx.doi.org/10.12890/2018_000865DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346775PMC

Clinical characteristics and etiologies of miliary nodules in the US; A single center study.

Am J Med 2019 Jan 16. Epub 2019 Jan 16.

Divisions of Critical Care, Pulmonary and Sleep Medicine, Department of Internal Medicine, University of Texas at Houston Health Science Center. Electronic address:

Background: Miliary nodules have been typically described as a radiological manifestation of disseminated tuberculosis. However, miliary nodules are known to occur in a wide variety of conditions. The primary objective of the study was to identify clinical characteristics and etiologies of miliary nodules within our institution. Read More

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http://dx.doi.org/10.1016/j.amjmed.2018.12.030DOI Listing
January 2019
2 Reads

Retrospective Analysis of 9 Cases of Primary Pulmonary Mucosa-Associated Lymphoid Tissue Lymphoma and Literature Review.

Med Sci Monit Basic Res 2018 Dec 24;24:233-240. Epub 2018 Dec 24.

Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China (mainland).

BACKGROUND Primary pulmonary mucosa-associated lymphoma tissue lymphoma is rare and is often misdiagnosed because of its diverse and nonspecific clinical features. The aim of this study was to raise awareness among clinicians and to share our experience of treating and managing such patients. MATERIAL AND METHODS This retrospective study was conducted between 1 January 2009 and 31 October 2017 at the First Affiliated Hospital of Guangxi Medical University. Read More

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http://dx.doi.org/10.12659/MSMBR.912762DOI Listing
December 2018
2 Reads

Comparative study of primary pulmonary cryptococcosis with multiple nodules or masses by CT and pathology.

Exp Ther Med 2018 Dec 17;16(6):4437-4444. Epub 2018 Sep 17.

Department of Respiratory Disease, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, P.R. China.

The manifestations of pulmonary cryptococcosis with multiple nodules or masses on computed tomography (CT) are diverse and difficult to differentiate from those of lung cancer and pulmonary tuberculosis. The present study compared the multislice spiral CT signs with pathological results and used the pathological results to explain the CT signs with the aim of improving the accuracy of the diagnosis of this disease. A retrospective analysis of 20 patients with primary pulmonary cryptococcosis with multiple nodules or masses was performed. Read More

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http://dx.doi.org/10.3892/etm.2018.6745DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257807PMC
December 2018
1 Read

Tuberculosis of the Thyroid Gland Presented as a Rapid Enlargement of a Preexisting Goiter.

Case Rep Endocrinol 2018 12;2018:4369531. Epub 2018 Nov 12.

Department of Endocrinology, La Rabta hospital, Faculty of Medicine, University of Tunis El Manar, Tunis, Tunisia.

Thyroid involvement with tuberculosis is an uncommon condition even in endemic countries. As its clinical presentation is not specific, diagnosis is often difficult and requires histopathological confirmation. Herein we report an observation of secondary tuberculosis of the thyroid gland in a woman with a type 2 diabetes mellitus and a primary hypothyroidism. Read More

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http://dx.doi.org/10.1155/2018/4369531DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260530PMC
November 2018
5 Reads

High-resolution mapping of fluoroquinolones in TB rabbit lesions reveals specific distribution in immune cell types.

Elife 2018 11 14;7. Epub 2018 Nov 14.

Public Health Research Institute, New Jersey Medical School, Rutgers, The State University of New Jersey, Newark, United States.

Understanding the distribution patterns of antibiotics at the site of infection is paramount to selecting adequate drug regimens and developing new antibiotics. Tuberculosis (TB) lung lesions are made of various immune cell types, some of which harbor persistent forms of the pathogen, . By combining high resolution MALDI MSI with histology staining and quantitative image analysis in rabbits with active TB, we have mapped the distribution of a fluoroquinolone at high resolution, and identified the immune-pathological factors driving its heterogeneous penetration within TB lesions, in relation to where bacteria reside. Read More

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https://elifesciences.org/articles/41115
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http://dx.doi.org/10.7554/eLife.41115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249001PMC
November 2018
10 Reads

Bronchial anthracofibrosis: The spectrum of radiological appearances.

Indian J Radiol Imaging 2018 Jul-Sep;28(3):333-341

Department of Imaging, Max Super Speciality Hospital, Saket, New Delhi, India.

Bronchial anthracofibrosis (BAF), caused by long-standing exposure to biomass fuel smoke, has emerged as a distinct pulmonary disease. It is usually seen in elderly females who have worked long hours in poorly ventilated kitchen full of smoke due to incomplete combustion of biomass fuel. The diagnosis is confirmed on bronchoscopic visualization of bluish-black anthracotic pigmentation along with narrowing/distortion of the affected bronchus. Read More

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http://www.ijri.org/text.asp?2018/28/3/333/242172
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http://dx.doi.org/10.4103/ijri.IJRI_339_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176667PMC
October 2018
24 Reads

A Young Patient with Stroke and Primary Tuberculosis.

J Neurosci Rural Pract 2018 Oct-Dec;9(4):613-615

Department of General Medicine, Sri Ramachandra Medical College and Research Institute, Chennai, Tamil Nadu, India.

A 21-year-old woman presented with left hemiparesis, fever, dyspnea, tachycardia, and pericardial rub on examination. She was provisionally diagnosed with infective endocarditis and received the final diagnosis of the primary pulmonary tuberculosis (PTB) and extra PTB (EPTB) with pericardial effusion and thoracic lymphadenitis. Left hemiparesis due to a pontine infarct was attributed to TB with neurovasculitis. Read More

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http://dx.doi.org/10.4103/jnrp.jnrp_59_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6126281PMC
October 2018
17 Reads

Impact of radiology reports on timely tuberculosis diagnosis.

Postgrad Med J 2018 Sep 19;94(1115):495-498. Epub 2018 Sep 19.

Division of Infectious Diseases and International Health, Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA

Purpose: As tuberculosis becomes less common in higher income countries, clinician familiarity with the disease is declining. Little is known about how chest radiograph interpretations affect tuberculosis care. We sought to determine how tuberculosis-related terminology in an initial chest radiograph reading impacted patient care. Read More

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http://dx.doi.org/10.1136/postgradmedj-2018-135984DOI Listing
September 2018

Nijmegen Breakage Syndrome Complicated With Primary Pulmonary Granulomas.

Pediatrics 2018 Oct 12;142(4). Epub 2018 Sep 12.

Departments of Pulmonology and Allergy and

Nijmegen breakage syndrome (NBS) is a rare autosomal recessive disease characterized by microcephaly, growth retardation, severe immunodeficiency, and predisposition to lymphoid malignancy. In this report, we describe a case of a 9-year-old boy, previously diagnosed with NBS and symptoms of dyspnea, dry cough, and fever. Despite initial recognition of pneumonia, there was no response to broad spectrum antimicrobial treatment, negative results from microbiological tests, and unclear changes in lung imaging were observed. Read More

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http://dx.doi.org/10.1542/peds.2018-0122DOI Listing
October 2018
2 Reads

Primary adrenal insufficiency due to bilateral infiltrative disease.

Endocrine 2018 12 3;62(3):721-728. Epub 2018 Sep 3.

Division of Endocrinology, Metabolism, and Nutrition, Department of Internal Medicine, Mayo Clinic, Rochester, MN, USA.

Purpose: Evidence on clinical presentation, evaluation, and management of patients with primary adrenal insufficiency (PAI) due to bilateral adrenal infiltrative disease is scarce. Our objective was to review the clinical presentation, biochemical work-up, imaging findings, and management of patients with PAI due to infiltrative adrenal disease in order to determine the best diagnostic and management approach.

Methods: Retrospective study of patients with PAI due to bilateral infiltrative adrenal disease referred for adrenal biopsy during 2000-2014 at Mayo Clinic, Rochester, Minnesota. Read More

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http://dx.doi.org/10.1007/s12020-018-1737-7DOI Listing
December 2018
10 Reads

Diffuse large B-cell lymphoma with pulmonary and cerebral involvement: A case report.

Mol Clin Oncol 2018 Sep 16;9(3):264-268. Epub 2018 Jul 16.

Department of Infectious Diseases, Capital Medical University Affiliated Beijing You An Hospital, Beijing 100069, P.R. China.

Primary diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin lymphoma; however, the involvement of the lung and central nervous system (CNS) in patients with DLBCL is rare. Furthermore, patients with DLBCL rarely exhibit specific clinical symptoms, which may delay definitive diagnosis. The present study reports the case of a 42-year-old man suffering from primary DLBCL with concurrent pulmonary and cerebral involvement. Read More

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http://dx.doi.org/10.3892/mco.2018.1673DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109671PMC
September 2018
9 Reads

Current trends and emerging diagnostic techniques for lung cancer.

Biomed Pharmacother 2018 Oct 28;106:1586-1599. Epub 2018 Jul 28.

Shobhaben Pratapbhai Patel School of Pharmacy and Technology Management, SVKM'S NMIMS, V.L. Mehta Road, Vile Parle (W), Mumbai, India.

Cancer is one of most fatal forms of disease with rapid, abnormal and uncontrolled division of cells which spreads into different organs in the body. The primary aim of this review is to showcase the current and emerging diagnostic techniques that are used in lung cancer detection. Lung cancer is a leading cause of death among smokers and it has been emerging in non-smokers due to passive smoke inhalation by non-smokers. Read More

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http://dx.doi.org/10.1016/j.biopha.2018.07.145DOI Listing
October 2018
10 Reads

Post-primary pulmonary TB haemoptysis - When there is more than meets the eye.

Respir Med Case Rep 2018 29;25:96-99. Epub 2018 Jul 29.

Department of Internal Medicine, Chris Hani Baragwanath Academic Hospital and Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.

Haemoptysis is concerning for both patient and healthcare provider and points to the presence of severe underlying lung disease warranting investigation. Approximately 8% of patients with pulmonary tuberculosis (PTB) infection will experience haemoptysis at some point during their life . The aetiology of haemoptysis in the setting of PTB is diverse and may occur during active or following prior PTB infection due to pulmonary complications. Read More

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http://dx.doi.org/10.1016/j.rmcr.2018.07.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080505PMC
July 2018
1 Read

[Pulmonary metastatic angiosarcoma presenting with diffuse alveolar hemorrhage: 9 case reports].

Zhonghua Nei Ke Za Zhi 2018 Aug;57(8):582-587

Department of Respiratory Medicine, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China.

Pulmonary metastatic angiosarcoma is a rare, fatal disease that often presents as diffuse alveolar hemorrhage(DAH). In this report, clinical characteristics of pulmonary metastatic angiosarcoma were retrospectively reviewed. A total of 9 patients with angiosarcoma who presented as DAH were enrolled. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0578-1426.2018.08.009DOI Listing
August 2018
27 Reads

Patterns of uveitis in patients with proven systemic (pulmonary and extrapulmonary) tuberculosis.

Int Ophthalmol 2018 Jul 18. Epub 2018 Jul 18.

Retina and Uvea Services, Dr R P Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, 110029, India.

Purpose: To report patterns of uveitis in patients with systemic tuberculosis.

Methods: Records of patients presenting at uvea clinic of a tertiary eye care centre were evaluated retrospectively, and 47 cases with proven systemic tuberculosis were analyzed for patterns of uveitis. Tuberculosis had been proven with a combination of radio imaging and detection of acid fast bacilli in body fluids. Read More

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http://dx.doi.org/10.1007/s10792-018-0989-9DOI Listing
July 2018
21 Reads

Diagnosis of human bovine tuberculosis aided by PET/CT scanning and EBUS-TBNA.

BMJ Case Rep 2018 Jul 16;2018. Epub 2018 Jul 16.

Department of Radiology, South Tees Hospitals NHS Foundation Trust, Middlesbrough, UK.

Human bovine tuberculosis is a rare zoonotic infection in developed countries which has been achieved predominantly by effective eradication programmes in cattle. The principal modes of transmission are consumption of unpasteurised dairy products and close contact with infected cattle. The clinical and radiological presentation is indistinguishable from tuberculosis caused by The diagnosis should be considered in individuals with relevant risk factors who present with intra/extrathoracic pathology. Read More

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http://dx.doi.org/10.1136/bcr-2018-225351DOI Listing
July 2018
9 Reads

Isolated hepatobiliary tuberculosis: a diagnostic challenge.

BMJ Case Rep 2018 Jun 6;2018. Epub 2018 Jun 6.

Department of Surgical Oncology, Jawaharlal Institute of Postgraduate Medical Education & Research, Puducherry, India.

Hepatobiliary system involvement is frequently seen as part of disseminated tubercular infection. But primary isolated hepatobiliary tuberculosis with no evidence of tuberculosis elsewhere in the body is extremely rare. Isolated hepatobiliary tuberculosis can cause diagnostic dilemma as the clinical, laboratory and imaging features are non-specific in majority of the cases. Read More

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http://casereports.bmj.com/lookup/doi/10.1136/bcr-2017-22391
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http://dx.doi.org/10.1136/bcr-2017-223912DOI Listing
June 2018
10 Reads

Addressing diversity in tuberculosis using multidimensional approaches.

Authors:
M Lerm H M Dockrell

J Intern Med 2018 May 27. Epub 2018 May 27.

Faculty of Infectious and Tropical Diseases, Department of Immunology and Infection, London School of Hygiene and Tropical Medicine, London, UK.

Tuberculosis is a complex disease, which can affect many organs other than the lungs. Initial infection may be cleared without inducing immunological memory, or progress directly to primary disease. Alternatively, the infection may be controlled as latent TB infection, that may progress to active tuberculosis at a later stage. Read More

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http://dx.doi.org/10.1111/joim.12776DOI Listing
May 2018
2 Reads

Left lung hypoplasia with a right tuberculous pleural effusion after childbirth: A case report.

Medicine (Baltimore) 2018 May;97(21):e10868

Department of Respiratory Medicine, Qinghai University Affiliated Hospital, Xining, China.

Rationale: Unilateral hypoplasia of the lung is a rare congenital condition, the mechanism of which is poorly understood. Primary pulmonary hypoplasia occurring in an adult is extremely rare and we present what is probably the first case of a link to a tuberculous pleural effusion in a young woman after childbirth.

Patient Concerns: Herein, we describe a 31-year-old woman with left lung hypoplasia, and she not only survived to adulthood without problems, but was able to deliver a baby in natural labor. Read More

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http://dx.doi.org/10.1097/MD.0000000000010868DOI Listing
May 2018
2 Reads

Correlation between clinical features, high-resolution computed tomography findings, and a visual scoring system in patients with pneumonia due to Mycoplasma pneumoniae.

Respir Investig 2018 Jul 4;56(4):320-325. Epub 2018 Apr 4.

Department of Respiratory Medicine, Kyorin University School of Medicine, Japan.

Background: Mycoplasma pneumoniae (MP) is the primary cause of community-acquired pneumonia. We aimed to evaluate the correlation between clinical features, with special reference to hypoxemia and the total affected area obtained using high-resolution computed tomography (HRCT).

Methods: Medical records of MP pneumonia patients > 15 years of age at Kyorin University Hospital between January 2006 and November 2013 were reviewed retrospectively and compared to patients with Streptococcus pneumoniae pneumonia, diagnosed between January 2013 and September 2014. Read More

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http://dx.doi.org/10.1016/j.resinv.2018.03.001DOI Listing
July 2018
9 Reads

Automated Chest X-Ray Screening: Can Lung Region Symmetry Help Detect Pulmonary Abnormalities?

IEEE Trans Med Imaging 2018 05;37(5):1168-1177

Our primary motivator is the need for screening HIV+ populations in resource-constrained regions for exposure to Tuberculosis, using posteroanterior chest radiographs (CXRs). The proposed method is motivated by the observation that radiological examinations routinely conduct bilateral comparisons of the lung field. In addition, the abnormal CXRs tend to exhibit changes in the lung shape, size, and content (textures), and in overall, reflection symmetry between them. Read More

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http://dx.doi.org/10.1109/TMI.2017.2775636DOI Listing
May 2018
3 Reads

Radiological signs associated with pulmonary multi-drug resistant tuberculosis: an analysis of published evidences.

Quant Imaging Med Surg 2018 Mar;8(2):161-173

Office of Cyber Infrastructure and Computational Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, USA.

Background: Despite that confirmative diagnosis of pulmonary drug-sensitive tuberculosis (DS-TB) and multidrug resistant tuberculosis (MDR-TB) is determined by microbiological testing, early suspicions of MDR-TB by chest imaging are highly desirable in order to guide diagnostic process. We aim to perform an analysis of currently available literatures on radiological signs associated with pulmonary MDR-TB.

Methods: A literature search was performed using PubMed on January 29, 2018. Read More

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http://dx.doi.org/10.21037/qims.2018.03.06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5891679PMC
March 2018
7 Reads

Mantle cell lymphoma presenting as bilateral adrenal huge masses.

BMJ Case Rep 2018 Apr 17;2018. Epub 2018 Apr 17.

Telemedicine Research Center (TRC), National Research Institute of Tuberculosis and Lung Diseases (NRITLD), University of Medical Sciences, Tehran, Iran.

We present a middle-aged woman complaining of weakness, lethargy and weight loss for 6 months. Positron emission tomography (PET)/CT scan revealed huge bilateral adrenal masses with intense 18F-fluorodeoxyglucose avidity. Biopsy and immunohistochemical staining were compatible with mantle cell lymphoma (MCL). Read More

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http://dx.doi.org/10.1136/bcr-2017-223247DOI Listing
April 2018
6 Reads

A review of the etiology and clinical presentation of non-cystic fibrosis bronchiectasis: A tertiary care experience.

Respir Med 2018 04 24;137:35-39. Epub 2018 Feb 24.

Hacettepe University Faculty of Medicine, Department of Pediatric Pulmonology, Ankara, Turkey.

Introduction: Non-cystic fibrosis(CF) bronchiectasis has been recognized in children for the past 200 years. Early childhood pneumonia and underlying conditions such as immunodeficiency, primary ciliary dyskinesia(PCD), and congenital lung pathology should be considered in the etiology. The aim of our study was to describe the clinical characteristics, laboratory, and radiological findings of a large population of patients with non-CF bronchiectasis at a tertiary center. Read More

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http://dx.doi.org/10.1016/j.rmed.2018.02.013DOI Listing
April 2018
8 Reads

Chronic Pulmonary Blastomycosis Mimicking Pulmonary Tuberculosis.

Mil Med 2018 07;183(7-8):e332-e333

Pulmonary and Critical Care Medicine, San Antonio Military Medical Center, 3551 Roger Brooke Drive, Fort Sam Houston, TX.

Introduction: Blastomyces dermatitidis is a dimorphic fungus endemic to the Mississippi River valley. We describe a rare case of chronic pulmonary blastomycosis complicated by large pulmonary cavitation in a young service member who was misdiagnosed with active pulmonary tuberculosis.

Case Presentation: A 25-year-old active duty male presented to his primary care provider with complaints of hemoptysis, fatigue, weight loss, and fever. Read More

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http://dx.doi.org/10.1093/milmed/usx122DOI Listing
July 2018
4 Reads

Diagnosis and management of Aspergillus diseases: executive summary of the 2017 ESCMID-ECMM-ERS guideline.

Clin Microbiol Infect 2018 May 12;24 Suppl 1:e1-e38. Epub 2018 Mar 12.

First Department of Medicine, Laiko Hospital, National and Kapodistrian University of Athens, Athens, Greece; German Centre for Infection Research (DZIF) partner site Bonn-Cologne, Cologne, Germany; CECAD Cluster of Excellence, University of Cologne, Cologne, Germany; Clinical Trials Center Cologne, University Hospital of Cologne, Cologne, Germany; ESCMID Fungal Infection Study Group (EFISG); European Confederation of Medical Mycology (ECMM); ESCMID European Study Group for Infections in Compromised Hosts (ESGICH). Electronic address:

The European Society for Clinical Microbiology and Infectious Diseases, the European Confederation of Medical Mycology and the European Respiratory Society Joint Clinical Guidelines focus on diagnosis and management of aspergillosis. Of the numerous recommendations, a few are summarized here. Chest computed tomography as well as bronchoscopy with bronchoalveolar lavage (BAL) in patients with suspicion of pulmonary invasive aspergillosis (IA) are strongly recommended. Read More

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http://dx.doi.org/10.1016/j.cmi.2018.01.002DOI Listing
May 2018
8 Reads

Clinical and misdiagnosed analysis of primary pulmonary lymphoma: a retrospective study.

BMC Cancer 2018 03 12;18(1):281. Epub 2018 Mar 12.

The First Affiliated Hospital of Wenzhou Medical University & Key Laboratory of Heart and Lung, Zhejiang, 325035, China.

Background: The primary pulmonary lymphoma (PPL), with a low incidence, was highly misdiagnosed in clinic. The present study analyzes the clinical features, laboratory and imaging data, pathologic characteristics, and summarizes misdiagnosis reasons of PPL cases, aims to provide a better understanding and increase the accuracy of early diagnosis and minimize the misdiagnosis of PPL.

Methods: The clinical data of 19 cases were collected from the first affiliated hospital of Wenzhou medical university (PRC) from April 2010 to May 2016. Read More

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http://dx.doi.org/10.1186/s12885-018-4184-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5848441PMC
March 2018
8 Reads

Frontal Lobe Tuberculoma: A Clinical and Imaging Challenge.

Ethiop J Health Sci 2017 Nov;27(6):677-680

Department of Pediatrics and Child Health, School of Medicine, College of Health Sciences, Addis Ababa University, Ethiopia.

Background: Pediatric nervous system tuberculomas are usually infra-tentorial and multiple. A frontal lobe location is rare.

Case Details: We report a 10 year-old boy who presented with a chronic headache and episodes of loss of consciousness. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811947PMC
November 2017
2 Reads

Pregnancy outcome in a pregnant patient with idiopathic Pulmonary Arterial Hypertension: a case report and review of the literature.

J Med Case Rep 2018 Feb 13;12(1):31. Epub 2018 Feb 13.

Department of Cardiology, Cardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.

Background: Idiopathic pulmonary arterial hypertension is a rare and progressive condition which is aggravated by the physiologic changes during pregnancy. Because of high mortality rate, most physicians recommend early termination of pregnancy in patients with idiopathic pulmonary arterial hypertension.

Case Presentation: Here we describe a case of a 30-year-old primigravida Caucasian housewife with functional class 1 idiopathic pulmonary arterial hypertension and a positive vasoreactive response to adenosine who had a full-term non-complicated delivery. Read More

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http://dx.doi.org/10.1186/s13256-017-1547-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5810109PMC
February 2018

The correlation between CT features and glycosylated hemoglobin level in patients with T2DM complicated with primary pulmonary tuberculosis.

Infect Drug Resist 2018 30;11:187-193. Epub 2018 Jan 30.

Department of Endocrinology, Shanghai Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China.

To investigate the correlation between computed tomography (CT) features and glycosylated hemoglobin (HbAlc) levels in patients with type 2 diabetes mellitus (T2DM) complicated with primary pulmonary tuberculosis (PTB). One hundred and eighty untreated PTB patients complicated with T2DM were selected. Based on the HbAlc level, the patients were divided into three groups: HbAlc level <7% (Group I: 32 patients), 7%-9% (Group II: 48 patients), and >9% (Group III: 100 patients). Read More

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http://dx.doi.org/10.2147/IDR.S146741DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796470PMC
January 2018
6 Reads

Calvarial Tuberculosis in a Preschool-Aged Child: An uncommon entity.

Sultan Qaboos Univ Med J 2017 Nov 10;17(4):e484-e486. Epub 2018 Jan 10.

Department of Neurology, AMRI Hospital, Kolkata, West Bengal, India.

Calvarial tuberculosis is a rare manifestation of tuberculosis, especially in children under five years of age. We report a two-and-a-half-year-old male child who presented to the Nilratan Sircar Medical College, Kolkata, India, in 2015 with frontoparietal fluctuant swelling of three months' duration. He had also had chronic sinus discharge from the left lower eyelid over the previous six months. Read More

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http://dx.doi.org/10.18295/squmj.2017.17.04.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766310PMC
November 2017

Humans in a Dish: The Potential of Organoids in Modeling Immunity and Infectious Diseases.

Front Microbiol 2017 5;8:2402. Epub 2017 Dec 5.

Division of Nanoscopy, Maastricht Multimodal Molecular Imaging Institute, Maastricht University, Maastricht, Netherlands.

For many decades, human infectious diseases have been studied in immortalized cell lines, isolated primary cells from blood and a range of animal hosts. This research has been of fundamental importance in advancing our understanding of host and pathogen responses but remains limited by the absence of multicellular context and inherent differences in animal immune systems that result in altered immune responses. Recent developments in stem cell biology have led to the growth of organoids that faithfully recapitulate a variety of human tissues including lung, intestine and brain amongst many others. Read More

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http://dx.doi.org/10.3389/fmicb.2017.02402DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5723307PMC
December 2017
7 Reads

Xpert MTB/RIF Ultra for detection of Mycobacterium tuberculosis and rifampicin resistance: a prospective multicentre diagnostic accuracy study.

Lancet Infect Dis 2018 01 30;18(1):76-84. Epub 2017 Nov 30.

FIND, Geneva, Switzerland. Electronic address:

Background: The Xpert MTB/RIF assay is an automated molecular test that has improved the detection of tuberculosis and rifampicin resistance, but its sensitivity is inadequate in patients with paucibacillary disease or HIV. Xpert MTB/RIF Ultra (Xpert Ultra) was developed to overcome this limitation. We compared the diagnostic performance of Xpert Ultra with that of Xpert for detection of tuberculosis and rifampicin resistance. Read More

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http://dx.doi.org/10.1016/S1473-3099(17)30691-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168783PMC
January 2018
24 Reads

Intrathoracic tuberculous lymphadenopathy in children: a guide to chest radiography.

Pediatr Radiol 2017 Sep 29;47(10):1277-1282. Epub 2017 Aug 29.

Department of Paediatrics and Child Health, Red Cross War Memorial Children's Hospital, University of Cape Town and Medical Research Council Unit on Child and Adolescent Health, Cape Town, South Africa.

Making the diagnosis of pulmonary tuberculosis in children can be difficult because microbiological confirmation is not often achieved. Diagnosis is therefore often based on clinical features in combination with chest radiograph findings. Chest radiographs can demonstrate lymphadenopathy of the hilar and para-tracheal regions on the anteroposterior view, and subcarinal lymphadenopathy on the lateral view. Read More

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http://dx.doi.org/10.1007/s00247-017-3890-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574962PMC
September 2017
6 Reads

Standardized radiographic interpretation of thoracic tuberculosis in children.

Pediatr Radiol 2017 Sep 29;47(10):1237-1248. Epub 2017 Aug 29.

Section of Pediatric Radiology, Institute of Radiology, St. Luke's Medical Center, Quezon City, Philippines.

There is a lack of standardized approach and terminology to classify the diverse spectrum of manifestations in tuberculosis. It is important to recognize the different clinical and radiographic patterns to guide treatment. As a result of changing epidemiology, there is considerable overlap in the radiologic presentations of primary tuberculosis and post-primary tuberculosis. Read More

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http://dx.doi.org/10.1007/s00247-017-3868-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574960PMC
September 2017
6 Reads

[Atypical inflammation of the middle ear].

Vestn Otorinolaringol 2017;82(4):9-15

L.I. Sverzhevskiy Research Institute of Clinical Otorhinolaryngology, Moscow Health Department, Moscow, Russia, 117152.

The objective of the present study was to characterize the patients presenting with atypical inflammation of the middle ear and consider the currently available methods for their examination. A total of 20 patients at the age from 16 to 66 years were admitted to the Department of Ear Microsurgery during the period from 2008 and 2016 for the treatment of atypical inflammation of the middle ear. Eleven of them (18 ears) were found to have tuberculous lesions (TL) of the middle ear while the remaining 9 patients (11 ears) suffered giant cell vasculitis (GCV). Read More

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http://dx.doi.org/10.17116/otorino20178249-15DOI Listing
November 2017
7 Reads

Two cases of the bronchial carcinoid tumors successfully treated with the parenchymal-sparing bronchoplastic resections.

J Thorac Dis 2017 Aug;9(8):E669-E673

Division of Angiology, Faculty of Health Science, Wroclaw Medical University, Wroclaw, Poland.

Carcinoid tumors account for 2% of primary lung tumors. We report two cases of the relatively young patients with typical and atypical carcinoid (AC) tumors that were managed successfully with a parenchymal-sparing bronchoplastic procedure. Read More

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http://dx.doi.org/10.21037/jtd.2017.06.141DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5594198PMC
August 2017
9 Reads

Predictors of conversion to thoracotomy during video-assisted thoracoscopic surgery lobectomy in lung cancer: additional predictive value of FDG-PET/CT in a tuberculosis endemic region.

J Thorac Dis 2017 Aug;9(8):2427-2436

Department of Nuclear Medicine, Kyungpook National University Medical Center, Daegu, South Korea.

Background: To evaluate the added clinical value of F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) scans to chest CT imaging in predicting the conversion to thoracotomy during video-assisted thoracoscopic surgery (VATS) lobectomy in patients with lung cancer.

Methods: This is a retrospective study of 235 consecutive patients who underwent planned VATS lobectomy for primary lung cancer between 2011 and 2015. CT images were interpreted in terms of the presence and the attenuation of peribronchial lymph nodes (PLN) and peribronchial cuffs of soft (PCS) tissue, pleural calcification, and parenchymal calcified nodule. Read More

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http://dx.doi.org/10.21037/jtd.2017.07.40DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5594172PMC
August 2017
62 Reads

Holistic care of complicated tuberculosis in healthcare settings with limited resources.

Arch Dis Child 2017 12 14;102(12):1161-1168. Epub 2017 Sep 14.

Discipline of Child Health, School of Medicine and Health Sciences, University of Papua New Guinea, Moresby, Papua New Guinea.

In recent years, most of the focus on improving the quality of paediatric care in low-income countries has been on improving primary care using the Integrated Management of Childhood Illness, and improving triage and emergency treatment in hospitals aimed at reducing deaths in the first 24 hours. There has been little attention paid to improving the quality of care for children with chronic or complex diseases. Children with complicated forms of tuberculosis (TB), including central nervous system and chronic pulmonary TB, provide examples of acute and chronic multisystem paediatric illnesses that commonly present to district-level and second-level referral hospitals in low-income countries. Read More

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http://dx.doi.org/10.1136/archdischild-2017-313095DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5754861PMC
December 2017
6 Reads

Primary Epithelioid Angiosarcoma of Lung: Radiologic and Clinicopathologic Correlation.

J Clin Imaging Sci 2017 24;7:33. Epub 2017 Aug 24.

Department of Radiology and Organ Imaging, United Christian Hospital, Kowloon, Hong Kong.

Primary pulmonary angiosarcoma is extremely rare. It is often characterized by a clinically indolent course and delayed diagnosis. To date, there have been <20 cases reported. Read More

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http://dx.doi.org/10.4103/jcis.JCIS_71_16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5582536PMC
August 2017
16 Reads

Clinical and diagnostic features of angiosarcoma with pulmonary metastases: A retrospective observational study.

Medicine (Baltimore) 2017 Sep;96(36):e8033

aDepartment of Respiratory Medicine bPathology Department cDepartment of Thoracic Surgery dRadiology Department, Peking Union Medical College Hospital, Dong Cheng District, Beijing, China.

Angiosarcoma with pulmonary metastasis is a rare, fatal disease that often presents with multiple pulmonary nodules and diffuse alveolar hemorrhage. We herein review the detailed clinical characteristics of pulmonary metastatic angiosarcoma and determine a reasonable diagnostic strategy.The medical records of 11 patients with pulmonary angiosarcoma were reviewed. Read More

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http://dx.doi.org/10.1097/MD.0000000000008033DOI Listing
September 2017
19 Reads

Etiology and outcome of moderate-to-massive hemoptysis: Experience from a tertiary care center of North India.

Int J Mycobacteriol 2017 Jul-Sep;6(3):307-310

Department of Internal Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Background: The aim of this study was to evaluate the etiology of hemoptysis in patients presenting to emergency department of Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.

Method: Prospectively 110 patients presenting to the emergency department with history of hemoptysis were screened for a period of one and half years. Out of these, 64 patients having true hemoptysis were enrolled in the study. Read More

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http://dx.doi.org/10.4103/ijmy.ijmy_54_17DOI Listing
April 2018
9 Reads

Role of FDG PET/CT Scan in Head and Neck Cancer Patients.

Arch Iran Med 2017 07;20(7):452-458

Chronic Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Introduction: PET/CT scan has an emerging role in head and neck oncology with a few well-established indications, including: detection of unknown primary tumor site, tumor staging, radiotherapy planning, treatment response assessment and detection of recurrent disease. The purpose of this study is reporting PET/CT findings in head and neck cancer patients to emphasize its role in head and neck oncology.

Materials And Methods: In a retrospective study, we reviewed our PET/CT database and found 94 patients with primary head and neck cancer. Read More

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July 2017
11 Reads

Defective positioning in granulomas but not lung-homing limits CD4 T-cell interactions with Mycobacterium tuberculosis-infected macrophages in rhesus macaques.

Mucosal Immunol 2018 03 26;11(2):462-473. Epub 2017 Jul 26.

T Lymphocyte Biology Unit, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.

Protection against Mycobacterium tuberculosis (Mtb) infection requires CD4 T cells to migrate into the lung and interact with infected macrophages. In mice, less-differentiated CXCR3 CD4 T cells migrate into the lung and suppress growth of Mtb, whereas CX3CR1 terminally differentiated Th1 cells accumulate in the blood vasculature and do not control pulmonary infection. Here we examine CD4 T-cell differentiation and lung homing during primary Mtb infection of rhesus macaques. Read More

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http://dx.doi.org/10.1038/mi.2017.60DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785573PMC
March 2018
6 Reads

Tuberculosis and its particularities in Romania and worldwide.

Rom J Morphol Embryol 2017 ;58(2):385-392

Department of Pulmonology, University of Medicine and Pharmacy of Craiova, Romania;

Tuberculosis (TB) is a global health issue, with a rising incidence since the beginning of this century. It poses a severe mortality risk and also poses a serious economic risk as it reduces the working capacity of an individual in the most productive part of life. Developing countries face widespread tuberculosis infection - up to 95% of all cases and 98% of deaths, respectively. Read More

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April 2018
10 Reads

Etiologic and differential diagnostic significance of tumor location in the supraclavicular fossa.

Laryngoscope 2018 03 20;128(3):646-650. Epub 2017 Jul 20.

Department of Otorhinolaryngology, Head and Neck Surgery, Charite'-Universitätsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany.

Objective: Patients presenting with a cervical mass are common for head and neck specialists and present a diagnostic challenge against the backdrop of a wide variety of etiologies. The objective of the present study was to evaluate the significance of a mass in the supraclavicular fossa for etiology, diagnostic procedure, and therapy.

Study Design: Individual retrospective cohort study. Read More

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http://doi.wiley.com/10.1002/lary.26775
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http://dx.doi.org/10.1002/lary.26775DOI Listing
March 2018
6 Reads

The impact of glycemic status on radiological manifestations of pulmonary tuberculosis in diabetic patients.

PLoS One 2017 19;12(6):e0179750. Epub 2017 Jun 19.

Department of Chest Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.

Setting: Diabetes mellitus (DM) may increase risk of pulmonary tuberculosis (PTB) and influence its radiological manifestations.

Objective: To evaluate the impact of glycemic status on radiological findings of PTB in diabetic patients.

Methods: Between January 2010 and December 2015, chest radiographs (CXRs) in consecutive 214 DM patients with culture-proved PTB and 123 available thoracic computed tomography (CT) scans were enrolled. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0179750PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476287PMC
September 2017
12 Reads

Characteristics and clinical role of bronchoscopy in diagnosis of childhood endobronchial tuberculosis.

World J Pediatr 2017 Dec 15;13(6):599-603. Epub 2017 Jun 15.

Department of Respiratory Diseases, Beijing Children'ss Hospital, Capital Medical University, National Center for Children'ss Health, Beijing, China.

Background: Endobronchial tuberculosis (EBTB) is the most frequent complication of primary pulmonary tuberculosis (PTB) in children. The aim of the study was to analyze characteristics and clinical role of bronchoscopy in diagnosis of childhood EBTB.

Methods: A retrospective, descriptive study was undertaken in 157 children with EBTB undergone flexible bronchoscopy (FB) between January 2006 and June 2014. Read More

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http://dx.doi.org/10.1007/s12519-017-0046-1DOI Listing
December 2017
49 Reads

Efficacy of Mycobacterium vaccae immunotherapy for patients with tuberculosis: A systematic review and meta-analysis.

Hum Vaccin Immunother 2017 09 12;13(9):1960-1971. Epub 2017 Jun 12.

a Division of Chest Medicine, Department of Internal Medicine , Hsinchu Mackay Memorial Hospital , Hsinchu , Taiwan.

Tuberculosis (TB) is a significant cause of illness and death worldwide. Immunotherapy has been investigated in the treatment of TB. The purpose of this study was to perform a meta-analysis investigating the effectiveness of the M. Read More

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http://dx.doi.org/10.1080/21645515.2017.1335374DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5612516PMC
September 2017
8 Reads