J Pain Symptom Manage 2021 Jun 17. Epub 2021 Jun 17.
Neuro-Oncology Branch, National Cancer Institute, National Institutes of Health, 9030 Old Georgetown Rd, Bethesda, Maryland, 20892, USA; Office of Research Services, Division of Library Services, National Institutes of Health, Bethesda, Maryland, USA.
Context: Interest in implementing palliative care for adults living with progressive central nervous system diseases (PCNSD) and their caregivers is increasing.
Objectives: To inform evidence-based practice and future research by critically evaluating randomized clinical trials (RCTs) investigating palliative care interventions (PCIs) for adults living with PCNSD and their caregivers using self-reported outcomes and the patient- and caregiver-reported outcome measures employed.
Methods: A systematic search using PRISMA methods of EMBASE, PubMed, Scopus, Web of Science databases using index and keyword methods for articles published from inception through 28 February 2021 was performed. Read More