15,052 results match your criteria Primary Insomnia


Comparative Effectiveness of Cheonwangbosimdan (Tian Wang Bu Xin Dan) Versus Cognitive-Behavioral Therapy for Insomnia in Cancer Patients: A Randomized, Controlled, Open-Label, Parallel-Group, Pilot Trial.

Integr Cancer Ther 2020 Jan-Dec;19:1534735420935643

Korea Institute of Oriental Medicine, Daejeon, Republic of Korea.

Cancer patients have a 2 times higher prevalence of insomnia than healthy populations and cancer-related insomnia has received minimal attention while insomnia can aggravate the rehabilitation of cancer patients. Cheonwangbosimdan is a Korean herbal medicine generally used to relieve sleep deprivation, however, few studies presented the effects of Cheonwangbosimdan on cancer-related insomnia. The purpose of study is to examine the feasibility of Cheonwangbosimdan treatments for cancer patients. Read More

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http://dx.doi.org/10.1177/1534735420935643DOI Listing

Sleep in hospitalized patients with chronic obstructive pulmonary disease: an observational study.

J Clin Sleep Med 2020 Jun 29. Epub 2020 Jun 29.

Section of General Internal Medicine, University of Chicago Medical Center, Chicago, Illinois.

Study Objectives: The aim of this study was to compare risk of undiagnosed sleep disorders among medical inpatients with COPD compared to those without COPD.

Methods: In a prospective cohort study, hospitalized medical ward patients without a known sleep disorder were screened for sleep disorders such as obstructive sleep apnea and insomnia while hospitalized using validated questionnaires. Daily sleep duration and efficiency in the hospital were measured via wrist actigraphy. Read More

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http://dx.doi.org/10.5664/jcsm.8646DOI Listing

Adolescent Alcohol Exposure Increases Orexin-A/Hypocretin-1 in the Anterior Hypothalamus.

Alcohol 2020 Jun 30. Epub 2020 Jun 30.

Department of Neuroscience, The Scripps Research Institute, La Jolla CA 92037. Electronic address:

Adolescence is a time of marked changes in sleep, neuromaturation, and alcohol use. While there is substantial evidence that alcohol disrupts sleep and that disrupted sleep may play a role in the development of alcohol use disorders (AUD), there is very little known about the brain mechanisms underlying this phenomenon. The orexin (also known as hypocretin) system is fundamental for a number of homeostatic mechanisms including the initiation and maintenance of wakefulness that may be impacted by adolescent alcohol exposure. Read More

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http://dx.doi.org/10.1016/j.alcohol.2020.06.003DOI Listing

Altered response to repetitive transcranial magnetic stimulation in patients with chronic primary insomnia.

Sleep Med 2020 Apr 5;72:126-129. Epub 2020 Apr 5.

Department of Psychology, University of Akureyri, Iceland.

Background: We aimed at evaluating the amplitude changes of the motor evoked potentials (MEPs) induced by of low-frequency (LF) repetitive transcranial magnetic stimulation (rTMS) over the primary motor cortex (M1) in10 patients with primary insomnia (PI) and in 10 age-matched healthy controls.

Methods: Median peak-to-peak MEP amplitudes were assessed in all subjects at three times: at baseline (T), after the first train of a single rTMS session (T), and after the whole rTMS procedure (T). This consists of 20 trains of 1 Hz stimulation with 50 stimuli per train and an intertrain interval of 30 s. Read More

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http://dx.doi.org/10.1016/j.sleep.2020.03.030DOI Listing

Healthcare Utilization and Prevalence of Symptoms in Women with Menopause: A Real-World Analysis.

Int J Womens Health 2020 3;12:445-454. Epub 2020 Jun 3.

Kahn-Sagol-Maccabi Research and Innovation Institute, Maccabi Healthcare Services, Tel Aviv, Israel.

Objective: Self-reported studies estimated that as many as 50-75% of women experience symptoms during menopause; however, limited real-world clinical data are available to support this observation. The electronic databases of Maccabi Healthcare Services were used to describe the prevalence of menopause symptoms in Israel and to characterize patients with regard to socioeconomic status, comorbidities and use of healthcare services.

Methods: Females aged 45-54 years diagnosed with menopausal symptoms (N=17,046, cumulative incidence of 8% during the study period) were identified from the Maccabi Healthcare Services electronic database and matched to female members without menopause symptoms, one-to-one on birth year and enumeration area. Read More

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http://dx.doi.org/10.2147/IJWH.S246113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7293420PMC

High prevalence of musculoskeletal pain in individuals with severe obesity: sites, intensity, and associated factors.

Korean J Pain 2020 Jul;33(3):245-257

Programa de Pós-Graduação em Ciências da Saúde, Universidade Federal de Goiás, Brazil.

Background: Musculoskeletal pain is associated with obesity; however, information on factors associated with pain in adults with obesity and severe obesity is limited. The purpose of this study was to assess the prevalence of musculoskeletal pain by site and intensity of pain and associated factors in individuals with severe obesity (body mass index ≥ 35.0 kg/m). Read More

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http://dx.doi.org/10.3344/kjp.2020.33.3.245DOI Listing

Internet-based cognitive behavioural therapy for depression and anxiety among Arabic-speaking individuals in Sweden: a pilot randomized controlled trial.

Cogn Behav Ther 2020 Jun 30:1-20. Epub 2020 Jun 30.

Department of Behavioural Sciences and Learning, Linköping University , Linköping, Sweden.

Arabic-speaking immigrants and refugees constitute one of the largest immigrant groups in Sweden. Previous research on Arabic-speaking immigrants indicates elevated levels of psychological disorders, including depression and anxiety. The aim of the present pilot study was to examine the efficacy of an internet-delivered cognitive behavioural treatment (ICBT) in an Arabic-speaking immigrant population. Read More

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http://dx.doi.org/10.1080/16506073.2020.1771414DOI Listing

Psychiatric symptoms among patients with acute abdominal pain.

Scand J Gastroenterol 2020 Jun 30:1-8. Epub 2020 Jun 30.

Department of Clinical and Experimental Medicine, Psychiatry Section, Linköping University, Linkoping, Sweden.

Abdominal pain is a common cause of visits to emergency facilities. It is related to psychiatric disorders in primary care, but it is unclear if this also holds in emergency departments. Is to explore potential differences between diagnostic groups in patients with acute abdominal pain in an emergency ward regarding concurrent somatic-and psychiatric symptoms, 'Length of stay' (LOS) and perceived health. Read More

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http://dx.doi.org/10.1080/00365521.2020.1782464DOI Listing

Comparison of prevalence and associated factors of depressive disorder between patients with head and neck cancer and those with lung cancer at a tertiary hospital in Taiwan: a cross-sectional study.

BMJ Open 2020 Jun 29;10(6):e037918. Epub 2020 Jun 29.

Department of Child and Adolescent Psychiatry, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan

Objective: Depression is a common comorbidity in cancer patients. This study aimed to compare the prevalence and associated factors of depressive disorder between patients with head and neck cancer (HNC) and those with lung cancer (LC).

Design: This study used a cross-sectional design with consecutive sampling. Read More

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http://dx.doi.org/10.1136/bmjopen-2020-037918DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7328812PMC

Neuropsychological function is related to irritable bowel syndrome in women with premenstrual syndrome and dysmenorrhea.

Arch Gynecol Obstet 2020 Jun 27. Epub 2020 Jun 27.

Cellular and Molecular Research Center, Birjand University of Medical Sciences, Birjand, Iran.

Background: There is increasing evidence demonstrating the co-occurrence of primary dysmenorrhea (PD), premenstrual syndrome (PMS), and irritable bowel syndrome (IBS) in women. This study aimed to investigate whether women who have symptoms of IBS in addition to PD and PMS also report more severe or frequent menstruation-associated symptoms and psychological complications compared to women with PD and PMS alone.

Methods: The study group included 182 female University students aged 18-25 years. Read More

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http://dx.doi.org/10.1007/s00404-020-05659-3DOI Listing

The effect of the COVID-19 pandemic on healthcare workers' mental health.

Authors:
Heather Hall

JAAPA 2020 Jul;33(7):45-48

Heather Hall worked at urgent care facilities in the metro-Detroit area in Michigan when this article was written. The author has disclosed no potential conflicts of interest, financial or otherwise.

The novel coronavirus (SARS-CoV-2) that emerged in late 2019 in Wuhan, China, commonly presents as a severe acute respiratory disease referred to as coronavirus disease-2019 (COVID-19). The rapid spread of the disease created challenges for healthcare systems and forced healthcare workers to grapple with clinical and nonclinical stressors, including shortages of personal protective equipment, mortality and morbidity associated with COVID-19, fear of bringing the virus home to family members, and the reality of losing colleagues to the disease. Evidence from previous outbreaks, along with early evidence from the COVID-19 pandemic, suggests that these events have significant short- and long-term effects on the mental health of healthcare workers. Read More

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http://dx.doi.org/10.1097/01.JAA.0000669772.78848.8cDOI Listing

Oral Administration of S-Adenosylmethionine (SAMe) and Lactobacillus Plantarum HEAL9 Improves the Mild-To-Moderate Symptoms of Depression: A Randomized, Double-Blind, Placebo-Controlled Study.

Prim Care Companion CNS Disord 2020 Jun 25;22(4). Epub 2020 Jun 25.

Nutrilinea SRL, Varese, Italy.

Objective: To assess the effects of the combination of SAMe (S-adenosylmethionine) 200 mg and Lactobacillus plantarum (L. plantarum) HEAL9 1 × 10⁹ CFU for the overall symptomatology of mild-to-moderate depression.

Methods: This 6-week randomized, double-blind, placebo-controlled study included subjects aged 18-60 years with mild-to-moderate depression (according to ICD-10 diagnostic criteria) recruited from September 17, 2018, to October 5, 2018. Read More

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http://dx.doi.org/10.4088/PCC.19m02578DOI Listing

Prevalence and management of chronic insomnia in Swiss primary care: Cross-sectional data from the "Sentinella" practice-based research network.

J Sleep Res 2020 Jun 25:e13121. Epub 2020 Jun 25.

Institute of Primary Health Care (BIHAM), University of Bern, Bern, Switzerland.

We investigated the prevalence and treatment of patients with chronic insomnia presenting to Swiss primary care physicians (PCPs) part of "Sentinella", a nationwide practice-based research network. Each PCP consecutively asked 40 patients if they had sleep complaints, documented frequency, duration, comorbidities, and reported ongoing treatment. We analysed data of 63% (83/132) of the PCPs invited. Read More

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http://dx.doi.org/10.1111/jsr.13121DOI Listing

Brief Behavioral Treatment for Insomnia vs. Cognitive Behavioral Therapy for Insomnia: Results of a Randomized Noninferiority Clinical Trial Among Veterans.

Behav Ther 2020 Jul 20;51(4):535-547. Epub 2020 Feb 20.

VA Pittsburgh Healthcare System; RAND Corporation.

The goal of this study was to compare a brief behavioral treatment for insomnia (BBTI), which has fewer sessions (4), shorter duration (<30-45 minutes), and delivers treatment in-person plus phone calls to cognitive behavioral therapy for insomnia (CBTI), which has 5 in-person sessions. The hypothesis was BBTI would be noninferior to CBTI. The Reliable Change Index was used to establish a noninferiority margin (NIM) of 3. Read More

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http://dx.doi.org/10.1016/j.beth.2020.02.002DOI Listing

"Truly holistic?" Differences in documenting physical and psychosocial needs and hope in Portuguese palliative patients.

Palliat Support Care 2020 Jun 25:1-6. Epub 2020 Jun 25.

Department of Palliative, Rehabilitation and Integrative Medicine, University of Texas MD Anderson Cancer Center, Houston, TX, USA.

Objective: Palliative care (PC) aims to improve patients' and families' quality of life through an approach that relieves physical, psychosocial, and spiritual suffering, although the latter continues to be under-assessed and under-treated. This study aimed to describe the prevalence of physical, psychosocial, and hope assessments documented by a PC team in the first PC consultation.

Method: The retrospective descriptive analysis of all first PC consultations registered in our anonymized database (December 2018-January 2020), searching for written documentation regarding (1) Edmonton Symptom Assessment Scale (ESAS) physical subscale (pain, tiredness, nausea, drowsiness, appetite, shortness of breath, constipation, insomnia, and well-being), (2) the single question "Are you depressed?" (SQD), (3) the question "Do you feel anxious?" (SQA), (4) feeling a burden, (5) hope-related concerns, (6) the dignity question (DQ), and (7) will to live (WtL). Read More

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http://dx.doi.org/10.1017/S1478951520000413DOI Listing

A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials Evaluating the Evidence Base of Melatonin, Light Exposure, Exercise, and Complementary and Alternative Medicine for Patients with Insomnia Disorder.

J Clin Med 2020 Jun 22;9(6). Epub 2020 Jun 22.

Department of Psychiatry and Psychotherapy, Medical Center, Faculty of Medicine, University of Freiburg, 79104 Freiburg, Germany.

Insomnia is a prevalent disorder and it leads to relevant impairment in health-related quality of life. Recent clinical guidelines pointed out that Cognitive-Behavior Therapy for Insomnia (CBT-I) should be considered as first-line intervention. Nevertheless, many other interventions are commonly used by patients or have been proposed as effective for insomnia. Read More

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http://dx.doi.org/10.3390/jcm9061949DOI Listing

Symptoms of Daytime Sleepiness and Sleep Apnea among Pregnant Women.

Oman Med J 2020 May 21;35(3):e132. Epub 2020 Jun 21.

King Saud bin Abdulaziz University for Health Sciences, College of Medicine, Riyadh, Saudi Arabia.

Objectives: Despite the fact that sleep disturbances have been associated with poor maternal and neonatal health outcomes in pregnancy, no studies have assessed excessive daytime sleepiness or the risk for sleep apnea among pregnant Saudi Arabian women. We sought to estimate the prevalence of excessive daytime sleepiness (EDS) and the high risk for sleep apnea (OSA) in a sample of pregnant Saudi women.

Methods: An anonymous self-report questionnaire was completed by 517 pregnant women who attended obstetric outpatient clinics at King Abdulaziz Medical City, Riyadh, Saudi Arabia, for a routine pregnancy check. Read More

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http://dx.doi.org/10.5001/omj.2020.50DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7306166PMC

Effects of Open-Label, Adjunctive Ganaxolone on Persistent Depression Despite Adequate Antidepressant Treatment in Postmenopausal Women: A Pilot Study.

J Clin Psychiatry 2020 Jun 9;81(4). Epub 2020 Jun 9.

Neuroendocrine Unit, BUL 457B, Massachusetts General Hospital, Boston, MA 02114.

Objective: The neuroactive steroid metabolite of progesterone, allopregnanolone, is a positive allosteric modulator of γ-aminobutyric acid-A (GABAA) receptors and a putative treatment for mood disorders. This pilot study was performed to determine whether an oral allopregnanolone analog (ganaxolone) may be effective adjunctive therapy for persistent depression despite adequate antidepressant treatment in postmenopausal women.

Method: Ten postmenopausal women (mean ± SD age: 62. Read More

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http://dx.doi.org/10.4088/JCP.19m12887DOI Listing

A randomized controlled study of weighted chain blankets for insomnia in psychiatric disorders.

J Clin Sleep Med 2020 Jun 15. Epub 2020 Jun 15.

The Affective Disorder Outpatient Clinic at Psychiatry Southwest, Karolinska University Hospital Huddinge, Stockholm, Sweden.

Study Objectives: This study aimed to evaluate the effect of weighted chain blankets on insomnia and sleep-related daytime symptoms for patients with major depressive disorder, bipolar disorder, generalized anxiety disorder (GAD) and attention deficit hyperactivity disorder (ADHD).

Methods: One hundred twenty patients were randomized (1:1) to either a weighted metal chain blanket or a light plastic chain blanket for four weeks. The outcome was evaluated using the Insomnia Severity Index (ISI) as primary outcome measure and the Day and Night Diaries (DND), Fatigue Symptom Inventory (FSI), and Hospital Anxiety and Depression Scale (HADS) as secondary outcome measures. Read More

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http://dx.doi.org/10.5664/jcsm.8636DOI Listing

Lemborexant vs suvorexant for insomnia: A systematic review and network meta-analysis.

J Psychiatr Res 2020 May 28;128:68-74. Epub 2020 May 28.

Department of Psychiatry, Fujita Health University School of Medicine, Toyoake, Aichi, 470-1192, Japan.

We conducted a random-effects model network meta-analysis to examine differences between lemborexant and suvorexant in efficacy and safety outcomes for treating patients with insomnia. We searched Embase, MEDLINE, and CENTRAL from their inception until April/28/2020. Primary outcomes were subjective time to sleep onset (sTSO), subjective total sleep time (sTST), and subjective wake-after-sleep onset (sWASO) at week 1. Read More

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http://dx.doi.org/10.1016/j.jpsychires.2020.05.025DOI Listing

Longitudinal Relationships between Perceived Social Support and Symptom Outcomes: Findings from a sample of Adult Survivors of Childhood Sexual Abuse.

Child Abuse Negl 2020 Jun 8;107:104566. Epub 2020 Jun 8.

Department of Psychosocial Science, University of Bergen, Christiesgate 12, 5015 Bergen, Norway; Norwegian Competence Center of Sleep Disorders, Haukeland University Hospital, PO Box 1400, 5021 Bergen, Norway.

Introduction: Cross-sectional studies have consistently reported an inverse association between perceived social support and the severity of mental health symptoms among adult survivors of childhood sexual abuse (CSA). However, there is a lack of longitudinal studies investigating the bidirectional association between social support and the severity of symptoms among adult CSA-survivors, as well as the role of relational problems in predicting perceived social support and symptom levels over time. The present study addressed these questions in a sample of primarily female CSA-survivors. Read More

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http://dx.doi.org/10.1016/j.chiabu.2020.104566DOI Listing

Efficacy, acceptability, and tolerability of all available treatments for insomnia in the elderly: a systematic review and network meta-analysis.

Acta Psychiatr Scand 2020 Jun 10. Epub 2020 Jun 10.

Department of Psychiatry and Psychotherapy, School of Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.

Objectives: Symptoms of insomnia are highly prevalent in the elderly. A significant number of pharmacological and non-pharmacological interventions exist, but, up-to-date, their comparative efficacy and safety has not been sufficiently assessed.

Methods: We integrated the randomized evidence from every available treatment for insomnia in the elderly (>65 years) by performing a network meta-analysis. Read More

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http://dx.doi.org/10.1111/acps.13201DOI Listing

Doing More With Less: Review of Dolutegravir-Lamivudine, a Novel Single-Tablet Regimen for Antiretroviral-Naïve Adults With HIV-1 Infection.

Ann Pharmacother 2020 Jun 9:1060028020933772. Epub 2020 Jun 9.

University of Florida, Gainesville, FL, USA.

To review data on efficacy and safety of dolutegravir (DTG) and lamivudine (3TC) in treatment-naïve adults with HIV-1 infection. Phase III clinical trials and review articles were identified through PubMed (1996 to March 2020) and ClinicalTrials.gov (2000 to May 2020) using the keywords , and . Read More

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http://dx.doi.org/10.1177/1060028020933772DOI Listing

Treatment of somatic symptom disorder in childhood: evidence-based psychotherapy interventions

Orv Hetil 2020 06;161(25):1050-1058

Általános Orvostudományi Kar, Klinikai Pszichológia Tanszék,Semmelweis Egyetem Budapest, Üllői út 78., 1083.

Introduction: About 25-30% of patients present themselves in general practice and specialized healthcare with medically unexplained somatic symptoms. The prevalence of these symptoms is the highest among the elderly, children and adolescents. Approximately 20% of patients in primary care and 47% of them in specialized clinics are children between the age of 7-12 who seem to have somatic symptom disorder (SSD). Read More

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http://dx.doi.org/10.1556/650.2020.31740DOI Listing

Mental health outcomes of quarantine and isolation for infection prevention: A systematic umbrella review of the global evidence.

Epidemiol Health 2020 Jun 2:e2020038. Epub 2020 Jun 2.

The IIHMR University, Jaipur, India.

Objectives: Transmission of infectious diseases is often prevented by quarantine and isolation of the populations at risk. These approaches restrict the mobility, social interactions, and daily activities of the affected individuals. In recent novel coronavirus disease (COVID-19) pandemic, quarantine and isolation are being adopted in many contexts, which necessitates an evaluation of global evidence on how such measures impact the mental health outcomes among populations. Read More

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http://dx.doi.org/10.4178/epih.e2020038DOI Listing

Intra-Individual Variability in Sleep Schedule: Effects of an Internet-Based Cognitive-Behavioral Therapy for Insomnia Program and its Relation with Symptom Remission.

Sleep 2020 Jun 8. Epub 2020 Jun 8.

University of Virginia, Center for Behavioral Health and Technology, Charlottesville, VA, USA.

Study Objectives: Sleep schedule consistency is fundamental to cognitive behavioral therapy for insomnia (CBT-I), although there is limited evidence suggesting whether it predicts treatment response. This analysis tested whether: (1) an Internet-based CBT-I program affects intra-individual variability (IIV) in sleep schedule, and (2) sleep schedule IIV predicts insomnia symptom remission.

Methods: This secondary analysis compares participants (N=303) randomized to an Internet-based CBT-I program (SHUTi - Sleep Healthy Using the Internet) or Internet-based patient education (PE). Read More

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http://dx.doi.org/10.1093/sleep/zsaa115DOI Listing

Effectiveness of Auricular Acupuncture for Insomnia: An Overview of Systematic Reviews.

Evid Based Complement Alternat Med 2020 13;2020:6920902. Epub 2020 May 13.

School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, Guangdong Province 510515, China.

Objectives: The effectiveness of auricular acupuncture (AA) for insomnia is far from uniform. The aim of this overview was to summarize and critically evaluate the evidence from systematic reviews (SRs)/meta-analysis (MAs) and provide an overall verdict about the therapeutic value of AA for insomnia.

Methods: A search of relevant literature for SRs/MAs was performed on major medical databases. Read More

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http://dx.doi.org/10.1155/2020/6920902DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244956PMC
May 2020
1.880 Impact Factor

Effect of Acupuncture on Pregnancy-Related Insomnia and Melatonin: A Single-Blinded, Randomized, Placebo-Controlled Trial.

Nat Sci Sleep 2020 13;12:271-278. Epub 2020 May 13.

Maternal-Fetal Medicine Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.

Objective: The aim of the current study is to evaluate the efficacy and safety of acupuncture on sleep quality and overnight melatonin secretion, measured as urinary 6-sulfatoxymelatonin, in pregnant women.

Patients And Methods: This randomized, parallel, single-blinded (participant), controlled trial was conducted on 72 pregnant women with insomnia. Study participants were randomly assigned to either the intervention, 10 sessions of acupuncture treatment over a 3-week period, or control group by block randomization (1:1). Read More

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http://dx.doi.org/10.2147/NSS.S247628DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7231755PMC

[Recommendations on clinical application of Wuling Capsule in psychosomatic related disorders: an expert consensus].

Authors:

Zhonghua Nei Ke Za Zhi 2020 Jun;59(6):427-432

Psychosomatic related disorders are diseases closely related to psychosocial factors. Patients are often treated in the non-psychiatric department of general hospitals due to somatic symptoms, and physicians often fail to recognize psychological symptoms, and could not make a proper diagnosis. Therefore, the status of diagnosis and treatment of psychosomatic disorders needs to be improved urgently. Read More

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http://dx.doi.org/10.3760/cma.j.cn112138-20191223-00838DOI Listing

Comparison between acupuncture and cognitive behavioral therapy for primary insomnia: A protocol for systematic review and network meta-analysis.

Medicine (Baltimore) 2020 May;99(21):e20453

Rehabilitation and Health Preservation College, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China.

Background: Primary insomnia (PI) is a common disease affecting human health. As the side effects of drug therapy were revealed, people began to seek more safe and effective non-drug therapies. Cognitive behavioral therapy for insomnia (CBT-I) and acupuncture are 2 commonly used non-drug therapies. Read More

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http://dx.doi.org/10.1097/MD.0000000000020453DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7249967PMC

Impact of Oncological Therapy and Treatment on Cancer-Related Fatigue and Internal Coherence in Nonmetastasized Breast Cancer Patients.

Integr Cancer Ther 2020 Jan-Dec;19:1534735420917211

Research Institute Havelhöhe, Berlin, Germany.

L extracts (VA) are frequently used in integrative oncology. Aim of this study was to evaluate the impact of add-on VA applications on various patient-reported outcome measures. A longitudinal real-world study was conducted, using data from the Network Oncology clinical registry. Read More

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http://dx.doi.org/10.1177/1534735420917211DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7273755PMC

Down Syndrome Disintegrative Disorder: A Clinical Regression Syndrome of Increasing Importance.

Pediatrics 2020 Jun;145(6)

Department of Neurology, Children's Hospital Los Angeles, Los Angeles, California; and

Down syndrome disintegrative disorder (DSDD), a developmental regression in children with Down syndrome (DS), is a clinical entity that is characterized by a loss of previously acquired adaptive, cognitive, and social functioning in persons with DS usually in adolescence to early adulthood. Initially reported in 1946 as "catatonic psychosis," there has been an increasing interest among the DS community, primary care, and subspecialty providers in this clinical area over the past decade. This condition has a subacute onset and can include symptoms of mood lability, decreased participation in activities of daily living, new-onset insomnia, social withdrawal, autistic-like regression, mutism, and catatonia. Read More

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http://dx.doi.org/10.1542/peds.2019-2939DOI Listing

Cognitive behavioural therapy for insomnia in patients with rheumatoid arthritis: protocol for the randomised, single-blinded, parallel-group Sleep-RA trial.

Trials 2020 May 29;21(1):440. Epub 2020 May 29.

Copenhagen Center for Arthritis Research (COPECARE), Center for Rheumatology and Spine Diseases, Rigshospitalet, Glostrup, Denmark.

Background: More than half of patients with rheumatoid arthritis complain of insomnia, which is predominantly treated with hypnotic drugs. However, cognitive behavioural therapy for insomnia is recommended as the first-line treatment in international guidelines on sleep. Patients with rheumatoid arthritis suffer from debilitating symptoms, such as fatigue and pain, which can also be linked to sleep disturbance. Read More

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http://dx.doi.org/10.1186/s13063-020-04282-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7257190PMC

Mefloquine exposure as a cause of sleep disorders among US military personnel and veterans.

Sleep 2019 09;42(9)

Office of the Executive Director, The Quinism Foundation, White River Junction, VT.

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http://dx.doi.org/10.1093/sleep/zsz183DOI Listing
September 2019

Sleep disturbance and sleep insufficiency in primary caregivers and their children with cystic fibrosis.

J Cyst Fibros 2020 May 25. Epub 2020 May 25.

Division of Pulmonary Medicine, Cincinnati Children's Hospital Medical Center, United States; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, United States.

Background: Chronically ill children and their parents are at risk for sleep disorders and associated morbidity. Sleep disturbance prevalence and the relationships between parent and child sleep among children with CF are not well defined. Clarifying the presence and impact of sleep disturbances among pediatric CF patients and their parents could lead to improved health in this population. Read More

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http://dx.doi.org/10.1016/j.jcf.2020.04.003DOI Listing

The impact of social constraints on insomnia among African-American breast cancer survivors: The mediating role of fear of recurrence.

Psychooncology 2020 May 27. Epub 2020 May 27.

College of Medicine, Howard University, Washington, DC, USA.

Objective: Insomnia is a significant concern among African-American breast cancer survivors (BCS). Social constraints (SC)-receiving unsupportive or critical responses when expressing trauma-related emotions-and fear of recurrence (FOR) have been associated with insomnia. We examined FOR as a mediator in the relationship between SC and insomnia in African-American BCS. Read More

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http://dx.doi.org/10.1002/pon.5435DOI Listing

A brief sleep focused psychoeducation program for sleep-related outcomes in new mothers: A randomised controlled trial.

Sleep 2020 May 26. Epub 2020 May 26.

Sleep and Circadian Research Group (CIRUS) and NeuroSleep Centre of Research Excellence, Woolcock Institute of Medical Research, University of Sydney.

Study Objectives: Poor sleep is commonly problematic during pregnancy and postpartum and is associated with depression. This trial investigated the efficacy of prenatal brief, group sleep psychoeducation in improving postpartum maternal sleep and depression.

Methods: 215 healthy expectant first-time mothers were cluster randomised (1:1) to receive either a 2 x 1. Read More

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http://dx.doi.org/10.1093/sleep/zsaa101DOI Listing

Evidence Base of Clinical Studies on Qi Gong: A Bibliometric Analysis.

Complement Ther Med 2020 May 6;50:102392. Epub 2020 Apr 6.

Centre for Evidence Based Chinese Medicine, Beijing University of Chinese Medicine, Beijing, 100029, China; Institute of Integrated Traditional Chinese Medicine and Western Medicine, Guangzhou Medical University, Guangzhou, China. Electronic address:

Objective: This bibliometric study aimed to systematically and comprehensively summarize the volume, breadth and evidence for clinical research on Qigong. And this bibliometric analysis also can provide the evidence of this field.

Design: Bibliometric analysis. Read More

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http://dx.doi.org/10.1016/j.ctim.2020.102392DOI Listing

Insomnia Among Elderly Primary Care Patients in India.

Prim Care Companion CNS Disord 2020 May 21;22(3). Epub 2020 May 21.

Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore, India.

Objective: To assess insomnia and its health correlates among elderly primary care patients in India.

Methods: A multicenter, cross-sectional survey was administered to 1,770 elderly primary care patients from 71 government primary health centers in Kerala, India, from May to December 2016. Insomnia was evaluated using the Insomnia Severity Index. Read More

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http://dx.doi.org/10.4088/PCC.19m02581DOI Listing

Early Childhood Sleep Intervention in Urban Primary Care: Clinician and Caregiver Perspectives.

J Pediatr Psychol 2020 May 20. Epub 2020 May 20.

Perelman School of Medicine, University of Pennsylvania.

Background: Despite significant income-related disparities in pediatric sleep, few early childhood sleep interventions have been tailored for or tested with families of lower socio-economic status (SES). This qualitative study assessed caregiver and clinician perspectives to inform adaptation and implementation of evidence-based behavioral sleep interventions in urban primary care with families who are predominantly of lower SES.

Methods: Semi-structured interviews were conducted with (a) 23 caregivers (96% mothers; 83% Black; 65% ≤125% U. Read More

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http://dx.doi.org/10.1093/jpepsy/jsaa024DOI Listing

Cannabidiol (CBD) and Δ-tetrahydrocannabinol (THC) for chronic insomnia disorder ('CANSLEEP' trial): protocol for a randomised, placebo-controlled, double-blinded, proof-of-concept trial.

BMJ Open 2020 May 18;10(5):e034421. Epub 2020 May 18.

Woolcock Institute of Medical Research, Centre for Sleep and Chronobiology, Sydney, New South Wales, Australia

Introduction: Insomnia is a highly prevalent and costly condition that is associated with increased health risks and healthcare utilisation. Anecdotally, cannabis use is frequently reported by consumers to promote sleep. However, there is limited research on the effects of cannabis on sleep and daytime function in people with insomnia disorder using objective measures. Read More

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http://dx.doi.org/10.1136/bmjopen-2019-034421DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7239553PMC

Low-Intensity Cognitive Behavioral Therapy for Insomnia as the Entry of the Stepped-Care Model in the Community: A Randomized Controlled Trial.

Behav Sleep Med 2020 May 20:1-17. Epub 2020 May 20.

Department of Psychiatry, Queen Mary Hospital, Hong Kong, Hong Kong SAR.

: Diverse low-intensity interventions are available as the entry points in the stepped-care model for insomnia. The study aims to compare a single-session cognitive behavioral therapy for insomnia (CBTI) workshop, self-help CBTI and sleep hygiene education (SHE) workshop among adults with insomnia in the community, in terms of insomnia severity, anxiety and depressive symptoms, the quality of life, treatment adherence and credibility.: Two-hundred-and-ten Hong Kong adults with DSM-5 defined insomnia disorder for at least one month were recruited in the community. Read More

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http://dx.doi.org/10.1080/15402002.2020.1764000DOI Listing

Three steps to flatten the mental health need curve amid the COVID-19 pandemic.

Depress Anxiety 2020 05;37(5):405-406

Department of Psychiatry, Community Psychiatry Program for Research in Implementation and Dissemination of Evidence Based Treatments (Community Psychiatry PRIDE), Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1002/da.23031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7272919PMC

Isolating the role of time in bed restriction in the treatment of insomnia: a randomised, controlled, dismantling trial comparing sleep restriction therapy with time in bed regularisation.

Sleep 2020 May 18. Epub 2020 May 18.

Sleep and Circadian Neuroscience Institute, Nuffield Department of Clinical Neurosciences, University of Oxford, UK.

Study Objectives: Sleep restriction therapy (SRT) is one of the most effective treatments for insomnia. Restriction of time in bed (TIB) is assumed to be the central mechanism through which SRT improves sleep consolidation and reduces insomnia symptoms. This hypothesis has never been directly tested. Read More

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http://dx.doi.org/10.1093/sleep/zsaa096DOI Listing

Anxiety predicts dyadic sleep characteristics in couples experiencing insomnia but not in couples without sleep disorders.

J Affect Disord 2020 Aug 12;273:122-130. Epub 2020 May 12.

School of Psychological Sciences and Turner Institute for Brain and Mental Health, Monash University, 18 Innovation Walk, Melbourne, Victoria, 3800, Australia. Electronic address:

Background: Anxiety and depression are commonly comorbid with sleep problems. Despite growing acknowledgement that bedpartners are important determinants of sleep quality, few studies have explored mental health as a risk factor for disrupted sleep of the bedpartner. We examined whether anxiety or depression symptoms predicted an individual's sleep or their bedpartner's sleep, in couples where one partner experienced insomnia and in couples without sleep disorders. Read More

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http://dx.doi.org/10.1016/j.jad.2020.04.031DOI Listing

Letter to the Editor Regarding the Article: "Quality of Sleep among Portuguese Anaesthesiologists: A Cross-Sectional Study".

Acta Med Port 2020 May 4;33(5):352. Epub 2020 May 4.

Centro Hospitalar de Setúbal. Setúbal. Portugal.

N/a. Read More

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http://dx.doi.org/10.20344/amp.13669DOI Listing

Jiao-tai-wan for insomnia symptoms caused by the disharmony of the heart and kidney: a study protocol for a randomized, double-blind, placebo-controlled trial.

Trials 2020 May 15;21(1):408. Epub 2020 May 15.

Department of Traditional Chinese Medicine, The First Affiliated Hospital of Wenzhou Medical University, Nanbaixiang, Ouhai District, Wenzhou, 325035, Zhejiang, China.

Background: Insomnia seriously affects people's normal lives and work. However, effective treatment strategies are scarce. The purpose of this study is to explore the efficacy and safety of Jiao-tai-wan (JTW) for ameliorating insomnia symptoms caused by disharmony of the heart and kidney. Read More

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http://dx.doi.org/10.1186/s13063-020-04299-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7227231PMC

Melatonin and melatonin agonists as treatments for benzodiazepines and hypnotics withdrawal in patients with primary insomnia. A systematic review.

Drug Alcohol Depend 2020 Jul 25;212:107994. Epub 2020 Apr 25.

Departamento de Ciencias Médicas Básicas: Unidad de Fisiología. Facultad de Ciencias de la Salud. Universidad de la Laguna, la Laguna, Santa Cruz de Tenerife, Spain.

Background: Hypnotics (HYP) and benzodiazepines (BZD) are medicines prescribed for the insomnia treatment. Many patients present difficulties in discontinuing the treatment once established. Melatonin (MLT) has been prescribed as a treatment for BZD/HYP detoxification. Read More

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http://dx.doi.org/10.1016/j.drugalcdep.2020.107994DOI Listing

Who Is Seeking Help for Sleep? A Clinical Profile of Patients in a Sleep Psychology Clinic.

Int J Behav Med 2020 May 13. Epub 2020 May 13.

École de psychologie, Pavillon Félix-Antoine-Savard, Université Laval, 2325 rue des Bibliothèques, local 1044, Québec, Québec, G1V 0A6, Canada.

Background: The present study outlines a clinical profile of an ecologically valid population consulting for sleep difficulties at the Sleep Psychology Clinic of the Consultation service of the School of Psychology of Université Laval .

Method: Patients self-report to the sleep clinic. Following a phone screening interview, patients present to the clinic for a semi-structured clinical interview for sleep and psychopathology, which is conducted by psychologists and doctorate psychology students. Read More

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http://dx.doi.org/10.1007/s12529-020-09882-9DOI Listing

A prospective study on prevalence and causes of insomnia among end-stage renal failure patients on hemodialysis in selected dialysis centers in Qassim, Saudi Arabia.

Saudi J Kidney Dis Transpl 2020 Mar-Apr;31(2):454-459

Department of Pharmacy Practice, Unaizah College of Pharmacy, Qassim University, Qassim, Saudi Arabia.

Studies directed toward improving the life quality of hemodialysis (HD) patients revealed different etiologies for insomnia. We aimed to assess the prevalence of insomnia and determine associated etiologies in the AL Qassim region. This interview-based questionnaire study was conducted in HD centers for assessment of insomnia and its related causes using a validated screening questionnaire, developed by the JPS health network. Read More

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http://dx.doi.org/10.4103/1319-2442.284021DOI Listing