166,246 results match your criteria Primary Health Care Research & Development[Journal]


Socioeconomic inequality and determinants of postnatal home visits made by public health midwives: An analysis of the Sri Lanka Demographic and Health Survey.

PLoS One 2019 24;14(4):e0215816. Epub 2019 Apr 24.

Department of Public Health, Faculty of Medicine, University of Kelaniya, Ragama, Sri Lanka.

Introduction: The impact of socioeconomic inequalities on health outcomes and service delivery is increasingly researched globally. This study assessed the overall and sector-wise socioeconomic inequality in postnatal home visits made by Public Health Midwives (PHMs) in Sri Lanka and decomposed the observed socioeconomic inequality into potential determinants.

Methods: Data from the Sri Lanka Demographic and Health Survey (SLDHS) 2006-07 were used. Read More

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0215816PLOS

Satisfaction with Emergency Departments and Other Mental Health Services among Patients with Mental Disorders.

Healthc Policy 2019 Feb;14(3):43-54

Associate ProfessorDepartment of Health Administration, Policy and EvaluationSchool of Public Health, University of MontrealMontreal, QC.

Background: Few studies have investigated satisfaction with emergency departments (EDs) among patients with mental health (MH) issues. This study evaluated the use of and satisfaction with EDs and other MH services among 328 patients with MH disorders, as well as specific characteristics of patient satisfaction and dissatisfaction.

Methods: A mixed-methods study was conducted in four EDs located in different administrative healthcare regions of Quebec (Canada). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.12927/hcpol.2019.25793DOI Listing
February 2019

National Cancer Institute (NCI) state of the science: Targeted radiosensitizers in colorectal cancer.

Cancer 2019 Apr 24. Epub 2019 Apr 24.

Clinical Radiation Oncology Branch, Radiation Research Program, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.

Colorectal cancer (CRC) represents a major public health problem as the second leading cause of cancer-related mortality in the United States. Of an estimated 140,000 newly diagnosed CRC cases in 2018, roughly one-third of these patients will have a primary tumor located in the distal large bowel or rectum. The current standard-of-care approach includes curative-intent surgery, often after preoperative (neoadjuvant) radiotherapy (RT), to increase rates of tumor down-staging, clinical and pathologic response, as well as improving surgical resection quality. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/cncr.32150DOI Listing

Association of Rivaroxaban With Thromboembolic Events in Patients With Heart Failure, Coronary Disease, and Sinus Rhythm: A Post Hoc Analysis of the COMMANDER HF Trial.

JAMA Cardiol 2019 Apr 24. Epub 2019 Apr 24.

Universite de Lorraine, INSERM Unite 1116, Vandoeuvre les Nancy, France.

Importance: Whether anticoagulation benefits patients with heart failure (HF) in sinus rhythm is uncertain. The COMMANDER HF randomized clinical trial evaluated the effects of adding low-dose rivaroxaban to antiplatelet therapy in patients with recent worsening of chronic HF with reduced ejection fraction, coronary artery disease (CAD), and sinus rhythm. Although the primary end point of all-cause mortality, myocardial infarction, or stroke did not differ between rivaroxaban and placebo, there were numerical advantages favoring rivaroxaban for myocardial infarction and stroke. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1001/jamacardio.2019.1049DOI Listing

Validity of the CES-D for depression screening in military service members with a history of mild traumatic brain injury.

Brain Inj 2019 Apr 24:1-9. Epub 2019 Apr 24.

b Defense and Veterans Brain Injury Center (DVBIC) San Antonio VA Polytrauma Rehabilitation Center, South Texas Veterans Healthcare System , San Antonio , Texas , USA.

Primary Objective: To advance knowledge about the value of the Center for Epidemiologic Studies - Depression scale (CES-D) for depression screening in military service members with a history of mild traumatic brain injury (mTBI).

Research Design: Retrospective data from 336 military service members with a history of mTBI were extracted from a TBI Repository at a large military medical center. Participants included in this study screened positive for mTBI in a primary care clinic or soldier readiness processing center and were enrolled in the TBI repository from November 6, 2014 to May 31, 2017. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/02699052.2019.1610191DOI Listing

Secondary prevention after stroke/transient ischemic attack, a randomized audit&feedback trial.

Acta Neurol Scand 2019 Apr 24. Epub 2019 Apr 24.

Karolinska Institutet Stroke Research Network at Södersjukhuset, Sweden.

Objectives: The clinical benefits of use of secondary preventive pharmacotherapy in ischemic stroke/TIA have been previously demonstrated. A potential target for facilitating use of recommended medication is primary care physicians. Therefore, we carried out an audit&feedback intervention aimed at primary care centers. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/ane.13109DOI Listing

Evaluation of quality of the family health strategy in the Federal District.

Rev Bras Enferm 2019 Mar-Apr;72(2):367-374. Epub 2019 Apr 18.

Hospital Israelita Albert Einstein.

Aim: To evaluate quality of the Family Health Strategy (FHS) in the National Program for Improving Access and Quality of Primary Care in the Federal District (FD) from the perspective of users.

Methods: Evaluative research carried out in 25 basic health units of the Federal District through a validated questionnaire assessing the following dimensions: access, gateway, bond, service range, coordination, family focus, community orientation, and health professionals.

Results: Service provision, qualification of professionals, quality of professional-user relationship, and continuity of care were the best evaluated dimensions, while family approach, community approach, and access were the worst. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1590/0034-7167-2018-0130DOI Listing

Contributions of the nurse's clinical practice to Primary Care.

Rev Bras Enferm 2019 Mar-Apr;72(2):354-359. Epub 2019 Apr 18.

Universidade Federal de Santa Catarina. Florianópolis-SC, Brasil.

Objective: To understand the repercussions of the nurse's clinical practice on Primary Health Care.

Method: Qualitative research with the theoretical and methodological contribution of Grounded Theory. Data collection took place between May and October 2016 in Florianópolis' Primary Care service. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1590/0034-7167-2018-0348DOI Listing
April 2019
2 Reads

Recommendations of Active Surveillance for Intermediate-risk Prostate Cancer: Results from a National Survey of Radiation Oncologists and Urologists.

Eur Urol Oncol 2019 Mar 31;2(2):189-195. Epub 2018 Aug 31.

Cancer Outcomes and Public Policy Effectiveness Research Center, Yale University, New Haven, CT, USA; Department of Medicine, Yale University, New Haven, CT, USA.

Background: While active surveillance (AS) for intermediate-risk prostate cancer (PCa) remains controversial, perceptions of AS and treatment recommendations among PCa specialists are largely unknown. Thus, we performed a national survey of radiation oncologists (ROs) and urologists (UROs) to elicit attitudes and AS recommendations for intermediate-risk PCa.

Objective: To determine whether AS for PCa is becoming readily accepted by PCa specialists in the USA. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.euo.2018.08.004DOI Listing

Problem-solving intervention to prevent depression in non-professional caregivers: a randomized controlled trial with 8 years of follow-up.

Psychol Med 2019 Apr 24:1-8. Epub 2019 Apr 24.

Department of Clinical Psychology and Psychobiology,University of Santiago de Compostela,Santiago de Compostela,Spain.

Background: Studies of psychological interventions for the prevention of depression have found significant effects in the short-term, but the long-term efficacy has yet to be determined. This study evaluated the 8-year effect of a randomized controlled trial for indicated prevention of depression in female caregivers.

Methods: A total of 173 non-professional female caregivers with subclinical depressive symptoms not meeting criteria for a major depressive episode (MDE) were randomized to either a brief problem-solving intervention (n = 89) or usual-care control group (n = 84). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1017/S0033291719000916DOI Listing

Primary healthcare accreditation standards: a systematic review.

Int J Health Care Qual Assur 2019 Mar;32(2):310-320

School of Nutrition and Food Sciences, Semnan University of Medical Sciences , Semnan, Iran.

Purpose: Accreditation is an essential component in primary healthcare (PHC) systems. The purpose of this paper is to investigate the most suitable PHC accreditation models and standards, worldwide, and to prepare a comprehensive and unbiased summary from research on these models.

Design/methodology/approach: A systematic search was undertaken using Web of Science, Scopus, Science Direct, Springer, PubMed and ProQuest databases in August 2016 and updated in January 2018. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1108/IJHCQA-02-2018-0052DOI Listing

Changes in prescription routines for treating hypothyroidism between 2001 and 2015 - an observational study of 929,684 primary care patients in Copenhagen.

Thyroid 2019 Apr 24. Epub 2019 Apr 24.

University of Copenhagen, The Research Unit for General Practice, Copenhagen, Denmark.

Background Increased public attention towards health and quality of life issues has led to more intensified screening for various medical conditions including hypothyroidism. A falling serum thyroid stimulating hormone (s-TSH) at initiation of levothyroxine (L-T4) treatment has been reported in the UK between 2001- 2009 indicating a falling TSH threshold which may lead to less benefit from therapy and possibly overtreatment. Objective To investigate changes in s-TSH threshold used by the general practitioners to initiate L-T4 therapy between 2001-2015 in Copenhagen. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1089/thy.2018.0539DOI Listing

Primary health care: an opportunity for early identification of people living with undiagnosed HIV infection.

HIV Med 2019 Apr 24. Epub 2019 Apr 24.

Department of Infectious Diseases, Odense University Hospital, Odense C, Denmark.

Objectives: We aimed to determine the fraction of HIV-diagnosed individuals who had primary health care (PHC) contacts 3 years prior to HIV diagnosis and whether the risk of HIV diagnosis and degree of immunodeficiency were associated with the frequency of visits or procedures performed.

Methods: We used data from national registries to conduct a population-based nested case-control study. Cases were individuals diagnosed with HIV infection in Denmark from 1998 to 2016. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/hiv.12735DOI Listing

Three Years Down the Road: The Aftermath of the CDC Guideline for Prescribing Opioids for Chronic Pain.

Adv Ther 2019 Apr 23. Epub 2019 Apr 23.

NEMA Research, Inc., Naples, FL, USA.

The 2016 CDC guidelines for opioid prescribing by primary care physicians have exposed some shortfalls in our thinking about opioid use and stranded many chronic pain patients with inadequate analgesia. Opioid prescribing rates started to decline in 2012, but still remain high. The response from providers to the 2016 guidelines have led to unintended consequences. Read More

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s12325-019-00954-1
Publisher Site
http://dx.doi.org/10.1007/s12325-019-00954-1DOI Listing
April 2019
4 Reads

Integration of Traditional Birth Attendants into Mental Healthcare: A Multistakeholder Qualitative Study Exploration.

Biomed Res Int 2019 21;2019:8195267. Epub 2019 Mar 21.

Africa Mental Health Research and Training Foundation, Nairobi, Kenya.

Background: A significant number of people with common mental disorders are undiagnosed or undetected at primary healthcare facilities. The experience of traditional birth attendants (TBAs) in reassuring perinatal mothers could be utilized in maternal mental healthcare. The aim of this study was to gain insight into the feasibility of integrating TBAs into maternal mental healthcare using multiple stakeholder views. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1155/2019/8195267DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448332PMC

Variability in the prescription of drugs with uncertain effectiveness. The case of SYSADOA in the Basque Country.

GMS Health Technol Assess 2018 5;14:Doc01. Epub 2018 Nov 5.

Pharmaceutical Unit, Barrualde-Galdakao Integrated Health Services Setting, Osakidetza, Basque Health Service, Amorebieta, Spain.

The majority of clinical practice guidelines do not recommend the use of SYSADOA (Symptomatic Slow Action Drugs for Osteoarthritis) for the treatment of osteoarthritis because of the lack of evidence or uncertainty around their efficacy. Nevertheless, the Spanish Public Health Service continues funding these drugs. The aim of this study is to describe the prescription status of SYSADOA in the primary care units of the Basque Country during 2011; to determine if variability exists among them; and to examine if the variability could be explained by the health care region each PC unit belongs to. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3205/hta000130DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460939PMC
November 2018

The changing landscape of professional practice in podiatry, lessons to be learned from other professions about the barriers to change - a narrative review.

J Foot Ankle Res 2019 16;12:23. Epub 2019 Apr 16.

University of Salford, Salford, UK.

Background: The delivery of healthcare is changing and aligned with this, the podiatry profession continues to change with evidence informed practice and extending roles. As change is now a constant, this gives clinicians the opportunity to take ownership to drive that change forward. In some cases, practitioners and their teams have done so, where others have been reluctant to embrace change. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13047-019-0333-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6469120PMC

Vaccine safety surveillance in Canada: Reports to CAEFISS, 2013-2016.

Can Commun Dis Rep 2018 Sep 6;44(9):206-214. Epub 2018 Sep 6.

CAEFISS: Canadian Adverse Events Following Immunization Surveillance System, Centre for Immunization and Respiratory Infectious Diseases, Public Health Agency of Canada, Ottawa, ON.

Background: Canada has one of the strongest vaccine safety surveillance systems in the world. This system includes both passive surveillance of all vaccines administered and active surveillance of all childhood vaccines.

Objectives: To provide 1) a descriptive analysis of the adverse events following immunization (AEFI) reports for vaccines administered in Canada, 2) an analysis of serious adverse events (SAEs) and 3) a list of the top ten groups of vaccines with the highest reporting rates. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.14745/ccdr.v44i09a04DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449118PMC
September 2018

Obesity, kidney dysfunction and hypertension: mechanistic links.

Nat Rev Nephrol 2019 Apr 23. Epub 2019 Apr 23.

Department of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, MS, USA.

Excessive adiposity raises blood pressure and accounts for 65-75% of primary hypertension, which is a major driver of cardiovascular and kidney diseases. In obesity, abnormal kidney function and associated increases in tubular sodium reabsorption initiate hypertension, which is often mild before the development of target organ injury. Factors that contribute to increased sodium reabsorption in obesity include kidney compression by visceral, perirenal and renal sinus fat; increased renal sympathetic nerve activity (RSNA); increased levels of anti-natriuretic hormones, such as angiotensin II and aldosterone; and adipokines, particularly leptin. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41581-019-0145-4DOI Listing

Predictive value of inflammatory markers for cancer diagnosis in primary care: a prospective cohort study using electronic health records.

Br J Cancer 2019 Apr 24. Epub 2019 Apr 24.

University of Exeter Medical School, Bristol, UK.

Background: Early identification of cancer in primary care is important and challenging. This study examined the diagnostic utility of inflammatory markers (C-reactive protein, erythrocyte sedimentation rate and plasma viscosity) for cancer diagnosis in primary care.

Methods: Cohort study of 160,000 patients with inflammatory marker testing in 2014, plus 40,000 untested matched controls, using Clinical Practice Research Datalink (CPRD), with Cancer Registry linkage. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41416-019-0458-xDOI Listing

Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweight.

Authors:
Leanne K Küpers Claire Monnereau Gemma C Sharp Paul Yousefi Lucas A Salas Akram Ghantous Christian M Page Sarah E Reese Allen J Wilcox Darina Czamara Anne P Starling Alexei Novoloaca Samantha Lent Ritu Roy Cathrine Hoyo Carrie V Breton Catherine Allard Allan C Just Kelly M Bakulski John W Holloway Todd M Everson Cheng-Jian Xu Rae-Chi Huang Diana A van der Plaat Matthias Wielscher Simon Kebede Merid Vilhelmina Ullemar Faisal I Rezwan Jari Lahti Jenny van Dongen Sabine A S Langie Tom G Richardson Maria C Magnus Ellen A Nohr Zongli Xu Liesbeth Duijts Shanshan Zhao Weiming Zhang Michelle Plusquin Dawn L DeMeo Olivia Solomon Joosje H Heimovaara Dereje D Jima Lu Gao Mariona Bustamante Patrice Perron Robert O Wright Irva Hertz-Picciotto Hongmei Zhang Margaret R Karagas Ulrike Gehring Carmen J Marsit Lawrence J Beilin Judith M Vonk Marjo-Riitta Jarvelin Anna Bergström Anne K Örtqvist Susan Ewart Pia M Villa Sophie E Moore Gonneke Willemsen Arnout R L Standaert Siri E Håberg Thorkild I A Sørensen Jack A Taylor Katri Räikkönen Ivana V Yang Katerina Kechris Tim S Nawrot Matt J Silver Yun Yun Gong Lorenzo Richiardi Manolis Kogevinas Augusto A Litonjua Brenda Eskenazi Karen Huen Hamdi Mbarek Rachel L Maguire Terence Dwyer Martine Vrijheid Luigi Bouchard Andrea A Baccarelli Lisa A Croen Wilfried Karmaus Denise Anderson Maaike de Vries Sylvain Sebert Juha Kere Robert Karlsson Syed Hasan Arshad Esa Hämäläinen Michael N Routledge Dorret I Boomsma Andrew P Feinberg Craig J Newschaffer Eva Govarts Matthieu Moisse M Daniele Fallin Erik Melén Andrew M Prentice Eero Kajantie Catarina Almqvist Emily Oken Dana Dabelea H Marike Boezen Phillip E Melton Rosalind J Wright Gerard H Koppelman Letizia Trevisi Marie-France Hivert Jordi Sunyer Monica C Munthe-Kaas Susan K Murphy Eva Corpeleijn Joseph Wiemels Nina Holland Zdenko Herceg Elisabeth B Binder George Davey Smith Vincent W V Jaddoe Rolv T Lie Wenche Nystad Stephanie J London Debbie A Lawlor Caroline L Relton Harold Snieder Janine F Felix

Nat Commun 2019 Apr 23;10(1):1893. Epub 2019 Apr 23.

The Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.

Birthweight is associated with health outcomes across the life course, DNA methylation may be an underlying mechanism. In this meta-analysis of epigenome-wide association studies of 8,825 neonates from 24 birth cohorts in the Pregnancy And Childhood Epigenetics Consortium, we find that DNA methylation in neonatal blood is associated with birthweight at 914 sites, with a difference in birthweight ranging from -183 to 178 grams per 10% increase in methylation (P < 1.06 x 10). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41467-019-09671-3DOI Listing

Barriers to and facilitators of the identification, management and referral of childhood anxiety disorders in primary care: a survey of general practitioners in England.

BMJ Open 2019 Apr 23;9(4):e023876. Epub 2019 Apr 23.

School of Psychology & Clinical Language Sciences, University of Reading, Reading, UK.

Objectives: Although anxiety disorders are the most common emotional disorders in childhood and are associated with a broad range of negative outcomes, only a minority of affected children receive professional support. In the UK, general practitioners (GPs) are seen as 'gate-keepers' to mental health services. The aim of this study was to examine the extent to which GPs experience barriers to and facilitators of identifying, managing and accessing specialist services for these disorders, as well as factors associated with GPs' confidence. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/bmjopen-2018-023876DOI Listing

Chronic rhinosinusitis: a qualitative study of patient views and experiences of current management in primary and secondary care.

BMJ Open 2019 Apr 23;9(4):e022644. Epub 2019 Apr 23.

Norwich Medical School, University of East Anglia, Norwich, UK.

Objectives: To explore patient views and perspectives of current management of chronic rhinosinusitis (CRS) in primary and secondary care.

Design: Semistructured qualitative telephone interviews as part of the MACRO programme (Defining best Management for Adults with Chronic RhinOsinusitis).

Setting: Primary care and secondary care ear, nose and throat outpatient clinics in the UK. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/bmjopen-2018-022644DOI Listing

Statins for primary prevention of cardiovascular disease: modelling guidelines and patient preferences based on an Irish cohort.

Br J Gen Pract 2019 Apr 23. Epub 2019 Apr 23.

Department of General Practice, Royal College of Surgeons in Ireland, and Health Research Board Centre for Primary Care Research, Dublin, Ireland.

Background: Changes in clinical guidelines for primary prevention of cardiovascular disease (CVD) have widened eligibility for statin therapy.

Aim: To illustrate the potential impacts of changes in clinical guidelines.

Design And Setting: Modelling the impacts of seven consecutive European guidelines based on a cohort of people aged ≥50 years from the Irish Longitudinal Study on Ageing. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3399/bjgp19X702701DOI Listing

GPs' and practice staff's views of a telephone first approach to demand management: a qualitative study in primary care.

Br J Gen Pract 2019 Apr 23. Epub 2019 Apr 23.

Cambridge Centre for Health Services Research, Institute of Public Health, University of Cambridge, Cambridge.

Background: To better manage patient demand, some general practices have implemented a 'telephone first' approach in which all patients seeking a face-to-face appointment first have to speak to a GP on the telephone. Previous studies have suggested that there is considerable scope for this new approach, but there remain significant concerns.

Aim: To understand the views of GPs and practice staff of the telephone first approach, and to identify enablers and barriers to successful adoption of the approach. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3399/bjgp19X702401DOI Listing

Association of GP wellbeing and burnout with patient safety in UK primary care: a cross-sectional survey.

Br J Gen Pract 2019 Apr 23. Epub 2019 Apr 23.

School of Psychology, University of Leeds, Leeds.

Background: GPs have particularly high levels of burnout and poor wellbeing. Although both are associated with poorer safety outcomes within secondary care, there have been no quantitative studies investigating this within primary care. Furthermore, little is known about how occupational demands, burnout and wellbeing, and patient safety are all associated. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3399/bjgp19X702713DOI Listing

General medical services by non-medical health professionals: a systematic quantitative review of economic evaluations in primary care.

Br J Gen Pract 2019 Apr 23. Epub 2019 Apr 23.

Centre for Health Economics and Medicines Evaluation, Bangor University, Bangor.

Background: Previous systematic reviews have found that nurses and pharmacists can provide equivalent, or higher, quality of care for some tasks performed by GPs in primary care. There is a lack of economic evidence for this substitution.

Aim: To explore the costs and outcomes of role substitution between GPs and nurses, pharmacists, and allied health professionals in primary care. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3399/bjgp19X702425DOI Listing

Thromboembolic and haemorrhagic events in patients with atrial fibrillation: a prospective cohort study in UK primary and secondary care.

Br J Gen Pract 2019 Apr 23. Epub 2019 Apr 23.

Barts, and the London School of Medicine and Dentistry, Queen Mary University of London, London; research fellow, Department of Public Health and Primary Care, School of Clinical Medicine, University of Cambridge, Cambridge.

Background: Strong evidence on the long-term safety and efficacy of different types of anticoagulants would help clinicians to prevent thromboembolic events among patients with atrial fibrillation (AF) while minimising the risk of haemorrhages.

Aim: To estimate the risk of thromboembolic and haemorrhagic events for patients with AF on antiplatelets or anticoagulants.

Design And Setting: This was a cohort study using routinely collected UK primary and secondary care clinical data from patients with AF, aged ≥18 years, and with an indication to receive anticoagulation before April 2012. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3399/bjgp19X702269DOI Listing

The Patient-Held Active Record of Medication Status (PHARMS) study: a mixed-methods feasibility analysis.

Br J Gen Pract 2019 Apr 23. Epub 2019 Apr 23.

School of Public Health, University College Cork, Cork.

Background: Medication errors frequently occur as patients transition between hospital and the community, and may result in patient harm. Novel methods are required to address this issue.

Aim: To assess the feasibility of introducing an electronic patient-held active record of medication status device (PHARMS) at the primary-secondary care interface at the time of hospital discharge. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3399/bjgp19X702413DOI Listing

Manual or electroacupuncture as an add-on therapy to SSRIs for depression: A randomized controlled trial.

J Psychiatr Res 2019 Apr 9;114:24-33. Epub 2019 Apr 9.

Beijing University of Chinese Medicine, Centre for Evidence-Based Chinese Medicine, Beijing, 100029, China. Electronic address:

Selective serotonin reuptake inhibitors (SSRIs) are first-line antidepressants, however, only around 60% of patients could benefit from them. Acupuncture is supported by insufficient evidence to help with symptom relieving and SSRIs tolerance. This pragmatic randomized controlled trial compared SSRIs alone versus SSRIs together with manual acupuncture (MA) or electroacupuncture (EA) in moderate to severe depressed patients. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jpsychires.2019.04.005DOI Listing

Demographic, social and lifestyle risk factors for cancer registry-notified cancer of unknown primary site (CUP).

Cancer Epidemiol 2019 Apr 20;60:156-161. Epub 2019 Apr 20.

Centre for Big Data Research in Health, University of New South Wales Sydney, NSW, Australia.

Background: Little is known about the risk factors for cancer of unknown primary site (CUP). We examined the demographic, social and lifestyle risk factors for CUP in a prospective cohort of 266,724 people aged 45 years and over in New South Wales, Australia.

Methods: Baseline questionnaire data were linked to cancer registration, hospitalisation, emergency department admission, and mortality data. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.canep.2019.04.004DOI Listing

Implementation of a multicomponent intervention to prevent physical restraints in nursing homes (IMPRINT): A pragmatic cluster randomized controlled trial.

Int J Nurs Stud 2019 Apr 4. Epub 2019 Apr 4.

Institute of Health and Nursing Science, Medical Faculty, Martin Luther University Halle-Wittenberg, Magdeburger Str. 8, 06112 Halle (Saale), Germany; School of Nursing Science, Faculty of Health, Witten/Herdecke University, Stockumer Str. 12, 58453 Witten, Germany. Electronic address:

Background: Despite clear evidence for the lack of effectiveness and safety, physical restraints are frequently applied in nursing homes. Multicomponent interventions addressing nurses' attitudes and organizational culture have been effective in reducing physical restraints.

Objective: To evaluate the effectiveness of two versions of a guideline and theory-based multicomponent intervention to reduce physical restraints in nursing homes. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijnurstu.2019.03.017DOI Listing

Financial Support by Billionaires for Research and Policy Analysis Should Be Subject to Disclosure Rules.

J Stud Alcohol Drugs 2019 Mar;80(2):265-266

Department of Public Health & Primary Care, Trinity College Dublin, Dublin, Ireland.

View Article

Download full-text PDF

Source

Platelet-rich plasma versus lidocaine as tenotomy adjuvants in people with elbow epicondylopathy: a randomized controlled trial.

J Orthop Surg Res 2019 Apr 23;14(1):109. Epub 2019 Apr 23.

Regenerative Medicine, BioCruces Health Research Institute, Cruces University Hospital, 48903, Barakaldo, Spain.

Objectives: To determine the efficacy of platelet-rich plasma (PRP) compared to lidocaine as a tenotomy adjuvant for people with elbow tendinopathy.

Methods: Our study was a parallel-group, double-blind, randomized trial involving 71 patients with recalcitrant elbow tendinopathy who received two sessions of ultrasound-guided tenotomy with either PRP or lidocaine in a tertiary public hospital. The primary end point was the percentage of patients with an improvement exceeding 25% reduction in disability (Spanish version of the Disabilities of the Arm, Shoulder and Hand questionnaires-DASH-E) at 6 and 12 months; the secondary outcome was the percentage of patients exceeding 25% reduction in pain (VAS-P). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13018-019-1153-6DOI Listing

The value of international volunteers experience to the NHS.

Global Health 2019 Apr 23;15(1):31. Epub 2019 Apr 23.

Office of Health Economics, Southside 7th floor, 105 Victoria Street, London, SW1E 6QT, UK.

Background: Global Engagement works with health partnerships to establish workforce and educational translation on a global scale to support the National Health Service (NHS). There is growing evidence on how international experiences (through volunteering, exchanges and placements) benefit the NHS through an innovative workforce that develops international best practice and promotes lifelong learning. Most of this evidence has been captured though surveys to returned international volunteers. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12992-019-0473-yDOI Listing

Clinical performance comparators in audit and feedback: a review of theory and evidence.

Implement Sci 2019 Apr 24;14(1):39. Epub 2019 Apr 24.

NIHR Greater Manchester Primary Care Patient Safety Translational Research Centre, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK.

Background: Audit and feedback (A&F) is a common quality improvement strategy with highly variable effects on patient care. It is unclear how A&F effectiveness can be maximised. Since the core mechanism of action of A&F depends on drawing attention to a discrepancy between actual and desired performance, we aimed to understand current and best practices in the choice of performance comparator. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13012-019-0887-1DOI Listing

Expert panel process to optimise the design of a randomised controlled trial in chronic rhinosinusitis (the MACRO programme).

Trials 2019 Apr 23;20(1):230. Epub 2019 Apr 23.

Guy's and St. Thomas' NHS Foundation Trust, London, UK.

Background: MACRO (Defining best Management for Adults with Chronic RhinOsinusitis) is an NIHR-funded programme of work designed to establish best practice for adults with chronic rhinosinusitis (CRS). The 7-year programme comprises three consecutive workstreams, designed to explore NHS care pathways through analysis of primary and secondary data sources, and to undertake a randomised controlled trial to evaluate a longer-term course of macrolide antibiotics and endoscopic sinus surgery for patients with CRS. A number of outstanding elements still required clarification at the funding stage. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13063-019-3318-3DOI Listing

Reasons, perceived outcomes and characteristics of second-opinion seekers: are there differences in private vs. public settings?

BMC Health Serv Res 2019 Apr 23;19(1):238. Epub 2019 Apr 23.

Department of Primary Care and Public Health, School of Public Health, Imperial College London, The Reynolds Building, St. Dunstan's Road, London, W6 8RP, UK.

Background: In most countries, patients can get a second opinion (SO) through public or private healthcare systems. There is lack of data on SO utilization in private vs. public settings. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12913-019-4067-4DOI Listing

Primary care provider perceptions and experiences of implementing hepatitis C virus birth cohort testing: a qualitative formative evaluation.

BMC Health Serv Res 2019 Apr 23;19(1):236. Epub 2019 Apr 23.

Center for Healthcare Organization and Implementation Research, VA Boston Healthcare System, Boston, MA, USA.

Background: In 2014, the Department of Veterans Affairs (VA) adopted a screening test policy for hepatitis C virus (HCV) in all "Baby Boomers" - those born between 1945 and 1965. About 1 in 12 Veterans were estimated to be infected with HCV yet approximately 34% of the birth cohort remained untested. Early HCV diagnosis and successful antiviral treatment decrease the risk of onward transmission, cirrhosis, hepatocellular carcinoma, liver transplant, and death. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12913-019-4043-zDOI Listing

Reliability of routinely collected anthropometric measurements in primary care.

BMC Med Res Methodol 2019 Apr 24;19(1):84. Epub 2019 Apr 24.

Institute of Health Policy, Management and Evaluation, Dalla Lana School of Public Health, University of Toronto, Toronto, Canada.

Background: Measuring body mass index (BMI) has been proposed as a method of screening for preventive primary care and population surveillance of childhood obesity. However, the accuracy of routinely collected measurements has been questioned. The purpose of this study was to assess the reliability of height, length and weight measurements collected during well-child visits in primary care relative to trained research personnel. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12874-019-0726-8DOI Listing

The role of informal carers in the diagnostic process of heart failure: a secondary qualitative analysis.

BMC Cardiovasc Disord 2019 Apr 23;19(1):92. Epub 2019 Apr 23.

Nuffield Department of Primary Care Health Sciences, University of Oxford, Radcliffe Primary Care building, Radcliffe Observatory Quarter, Woodstock Road, Oxford, OX2 6GG, UK.

Background: Heart failure (HF) is a common clinical syndrome, particularly in older people, and symptoms can develop gradually. The aim of this study was to explore the role of informal carers in the HF diagnostic process.

Methods: Secondary analysis of qualitative interviews with 16 participants with a new diagnosis of HF. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12872-019-1075-6DOI Listing

Everyday ethical challenges of nurse-physician collaboration.

Nurs Ethics 2019 Apr 23:969733019840753. Epub 2019 Apr 23.

University of Pennsylvania, USA.

Background: Collaboration between physicians and nurses is key to improving patient care. We know very little about collaboration and interdisciplinary practice in African healthcare settings.

Research Question/aim: The purpose of this study was to explore the ethical challenges of interdisciplinary collaboration in clinical practice and education in Botswana Participants and research context: This qualitative descriptive study was conducted with 39 participants (20 physicians and 19 nurses) who participated in semi-structured interviews at public hospitals purposely selected to represent the three levels of hospitals in Botswana (referral, district, and primary). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/0969733019840753DOI Listing

Feasibility and Acceptability of 'Opt-In' Referrals for Stop Smoking Support in Pregnancy.

Int J Environ Res Public Health 2019 Apr 16;16(8). Epub 2019 Apr 16.

Division of Primary Care, University of Nottingham, Tower Building, University Park, Nottingham NG7 2RD, UK.

Background: International guidelines recommend that following an early-pregnancy 'opt-out' referral for smoking cessation support, pregnant women who smoke should also be offered referrals at subsequent antenatal appointments ('opt-in' referrals). We assessed feasibility and acceptability of introducing 'opt-in' self-referral forms to stop smoking services (SSS) in antenatal clinics.

Method: A 'before-after' service evaluation and qualitative interviews. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/ijerph16081358DOI Listing

Natural Antioxidant Resveratrol Suppresses Uterine Fibroid Cell Growth and Extracellular Matrix Formation In Vitro and In Vivo.

Antioxidants (Basel) 2019 Apr 12;8(4). Epub 2019 Apr 12.

School of Nutrition and Health Sciences, College of Nutrition, Taipei Medical University, Taipei 11031, Taiwan.

Resveratrol (RSV) is a polyphenolic phytoalexin found in peanuts, grapes, and other plants. Uterine fibroids (UF) are benign growths that are enriched in extracellular matrix (ECM) proteins. In this study, we aimed to investigate the effects of RSV on UF using in vivo and in vitro approaches. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/antiox8040099DOI Listing

Health Literacy: Current Status and Challenges in the Work of Family Doctors in Bosnia and Herzegovina.

Int J Environ Res Public Health 2019 Apr 12;16(8). Epub 2019 Apr 12.

Department for Primary Health Care, Faculty of Medicine, University of East Sarajevo, Studentska 5, 73300 Foca, Bosnia and Herzegovina.

Health literacy (HL) has become an important area of research. The aim of this study was to evaluate the HL of primary healthcare patients in the Republic of Srpska (RS), Bosnia and Herzegovina (B&H) and to identify socioeconomic and health factors associated with HL. This cross-sectional study among 768 patients was conducted in two healthcare centres between March and May 2017, using the Short Test of Functional Health Literacy in Adults (S-TOFHLA). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/ijerph16081324DOI Listing

Outcome of Robot-Assisted Bilateral Internal Mammary Artery Grafting via Left Pleura in Coronary Bypass Surgery.

J Clin Med 2019 Apr 12;8(4). Epub 2019 Apr 12.

Department of Cardiology, Kaohsiung Municipal United Hospital, Kaohsiung 804, Taiwan.

Studies are extremely limited for the investigation of the clinical outcome of da Vinci robot-assisted bilateral internal mammary artery (BIMA) grafting in coronary artery bypass grafting (CABG) surgery. This study aimed to explore the short-term outcome of da Vinci robot-assisted BIMA grafting through the left pleural space. Relevant data were collected from patients with multi-vessel coronary artery disease receiving two kinds of CABG: a group of patients receiving da Vinci robot-assisted CABG with BIMA grafting, and another group of patients receiving sternotomy CABG with BIMA grafting. Read More

View Article

Download full-text PDF

Source
https://www.mdpi.com/2077-0383/8/4/502
Publisher Site
http://dx.doi.org/10.3390/jcm8040502DOI Listing
April 2019
1 Read

Psychosocial Management Before, During, and After Emergencies and Disasters-Results from the Kobe Expert Meeting.

Int J Environ Res Public Health 2019 Apr 12;16(8). Epub 2019 Apr 12.

National Institute of Mental Health, National Center for Neurology and Psychiatry, Kodaira 187-0031, Japan.

Emergencies and disasters typically affect entire communities, cause substantial losses and disruption, and result in a significant and persistent mental health burden. There is currently a paucity of evidence on safe and effective individual- and community-level strategies for improving mental health before, during, and after such events. In October 2018, the World Health Organization (WHO) Centre for Health Development (WHO Kobe Centre) convened a meeting bringing together leading Asia Pacific and international disaster research experts. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/ijerph16081309DOI Listing

Determinants of Length of Stay Following Total Anterior Circulatory Stroke.

Geriatrics (Basel) 2017 Aug 4;2(3). Epub 2017 Aug 4.

Ageing Clinical & Experimental Research Team, Institute of Applied Health Sciences, School of Medicine, Medical Sciences & Nutrition, University of Aberdeen, Aberdeen AB25 2ZD, UK.

Identification of factors that determine length of stay (LOS) in total anterior circulatory stroke (TACS) has potential for targeted intervention to reduce the associated health care burden. This study aimed to determine which factors predict LOS following either ischaemic or haemorrhagic TACS. The study sample population was drawn from the Norfolk and Norwich Stroke and Transient Ischemic Attack (TIA) Register (1996⁻2012), a prospective registry. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/geriatrics2030026DOI Listing

Antipsychotic Adherence Intervention for Veterans over Forty with Schizophrenia: Results of a Pilot Study.

Clin Schizophr Relat Psychoses 2009 Jan;2(4):317-325

4 Veterans Administration San Diego Healthcare System and Advanced Center for Intervention and Services Research, University of California, San Diego.

This pilot study tested the feasibility, acceptability, and effect sizes of a multimodal, individual intervention designed to optimize antipsychotic medication use in patients ≥40 years of age with schizophrenia or schizoaffective disorder. We randomized forty patients into two groups: usual care (UC) versus a nine-session, manualized antipsychotic adherence intervention (AAI). The AAI attempted to improve adherence by combining three psychosocial techniques: 1) education; 2) skills training; and, 3) alliance building. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3371/CSRP.2.4.5DOI Listing
January 2009

The Association Between Telemedicine and Emergency Department (ED) Disposition: A Stepped Wedge Design of an ED-Based Telemedicine Program in Critical Access Hospitals.

J Rural Health 2019 Apr 23. Epub 2019 Apr 23.

Department of Health Management and Policy, University of Iowa College of Public Health, Iowa City, Iowa.

Purpose: To study the relationship between the availability and activation of emergency department-based telemedicine (teleED) and patient disposition in Critical Access Hospitals (CAHs).

Methods: A non randomized stepped wedge design examined 133,396 ED visits in 15 CAHs that subscribe to a single teleED provider. Data were available for at least 12 months prior to teleED implementation and at least 12 months of post-implementation. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/jrh.12370DOI Listing